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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DHGKAPPL_00001	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DHGKAPPL_00002	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DHGKAPPL_00003	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DHGKAPPL_00004	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHGKAPPL_00005	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_00006	2.64e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
DHGKAPPL_00007	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DHGKAPPL_00008	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DHGKAPPL_00009	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DHGKAPPL_00010	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00011	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_00013	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_00014	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DHGKAPPL_00016	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DHGKAPPL_00017	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
DHGKAPPL_00018	4.69e-202	degV1	-	-	S	-	-	-	DegV family
DHGKAPPL_00019	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_00020	3.79e-181	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
DHGKAPPL_00021	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DHGKAPPL_00022	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
DHGKAPPL_00023	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
DHGKAPPL_00024	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DHGKAPPL_00025	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DHGKAPPL_00026	3.87e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHGKAPPL_00027	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DHGKAPPL_00028	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
DHGKAPPL_00029	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
DHGKAPPL_00030	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
DHGKAPPL_00031	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
DHGKAPPL_00032	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
DHGKAPPL_00033	2.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
DHGKAPPL_00034	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DHGKAPPL_00035	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
DHGKAPPL_00036	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
DHGKAPPL_00037	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00038	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DHGKAPPL_00039	9.5e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00040	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
DHGKAPPL_00041	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_00042	1.52e-211	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_00043	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
DHGKAPPL_00044	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
DHGKAPPL_00045	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
DHGKAPPL_00046	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHGKAPPL_00047	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00048	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DHGKAPPL_00049	1.09e-275	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DHGKAPPL_00050	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
DHGKAPPL_00051	1.54e-247	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00052	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
DHGKAPPL_00053	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
DHGKAPPL_00054	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DHGKAPPL_00055	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00056	6.56e-28	-	-	-	-	-	-	-	-
DHGKAPPL_00057	3.95e-92	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DHGKAPPL_00058	2.79e-16	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DHGKAPPL_00059	6.05e-126	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DHGKAPPL_00060	4.22e-08	-	-	-	V	-	-	-	Domain of unknown function (DUF5011)
DHGKAPPL_00061	2.73e-196	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DHGKAPPL_00062	9.07e-22	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_00063	2.12e-27	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_00065	3.22e-46	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00066	2.48e-09	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00068	3.07e-06	-	-	-	D	-	-	-	Mycoplasma protein of unknown function, DUF285
DHGKAPPL_00070	2.15e-17	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DHGKAPPL_00071	2.28e-22	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_00072	4.32e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
DHGKAPPL_00073	2.03e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
DHGKAPPL_00076	2.76e-28	-	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00077	1.08e-208	-	-	-	-	-	-	-	-
DHGKAPPL_00079	1.48e-111	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_00080	2.11e-207	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_00081	8.3e-39	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_00082	2.72e-126	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DHGKAPPL_00083	1.46e-60	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DHGKAPPL_00084	1.05e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
DHGKAPPL_00085	3.4e-229	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00086	4.67e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
DHGKAPPL_00087	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DHGKAPPL_00088	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
DHGKAPPL_00089	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
DHGKAPPL_00090	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
DHGKAPPL_00091	1.45e-162	-	-	-	S	-	-	-	Membrane
DHGKAPPL_00092	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DHGKAPPL_00093	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_00094	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00095	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_00096	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DHGKAPPL_00098	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
DHGKAPPL_00099	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
DHGKAPPL_00100	9.62e-19	-	-	-	-	-	-	-	-
DHGKAPPL_00101	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DHGKAPPL_00102	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DHGKAPPL_00103	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
DHGKAPPL_00104	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
DHGKAPPL_00105	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
DHGKAPPL_00106	1.06e-16	-	-	-	-	-	-	-	-
DHGKAPPL_00107	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
DHGKAPPL_00108	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
DHGKAPPL_00109	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
DHGKAPPL_00110	5.02e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DHGKAPPL_00111	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00112	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGKAPPL_00113	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
DHGKAPPL_00114	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
DHGKAPPL_00115	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
DHGKAPPL_00116	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DHGKAPPL_00117	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DHGKAPPL_00118	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DHGKAPPL_00119	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
DHGKAPPL_00120	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00121	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_00122	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DHGKAPPL_00123	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DHGKAPPL_00124	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DHGKAPPL_00125	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00126	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00127	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
DHGKAPPL_00128	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DHGKAPPL_00129	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DHGKAPPL_00130	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHGKAPPL_00131	2.58e-186	yxeH	-	-	S	-	-	-	hydrolase
DHGKAPPL_00132	8.95e-225	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHGKAPPL_00134	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
DHGKAPPL_00135	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DHGKAPPL_00136	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHGKAPPL_00137	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DHGKAPPL_00138	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DHGKAPPL_00139	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00140	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00141	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00142	3.25e-252	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
DHGKAPPL_00143	8.71e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DHGKAPPL_00144	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00145	1.73e-178	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DHGKAPPL_00146	1.48e-103	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DHGKAPPL_00147	1.17e-96	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00148	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_00149	4.72e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DHGKAPPL_00150	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00151	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DHGKAPPL_00152	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00153	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00154	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DHGKAPPL_00155	2.4e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
DHGKAPPL_00156	1.25e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DHGKAPPL_00157	1.21e-315	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_00158	1.5e-171	-	-	-	K	-	-	-	UTRA domain
DHGKAPPL_00159	3.59e-198	estA	-	-	S	-	-	-	Putative esterase
DHGKAPPL_00160	2.09e-83	-	-	-	-	-	-	-	-
DHGKAPPL_00161	2.25e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_00162	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
DHGKAPPL_00163	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
DHGKAPPL_00164	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DHGKAPPL_00165	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DHGKAPPL_00166	9.89e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DHGKAPPL_00167	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_00168	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
DHGKAPPL_00169	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DHGKAPPL_00170	2.2e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DHGKAPPL_00171	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DHGKAPPL_00172	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHGKAPPL_00173	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
DHGKAPPL_00174	5.16e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DHGKAPPL_00175	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00176	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DHGKAPPL_00177	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DHGKAPPL_00178	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DHGKAPPL_00179	6.68e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
DHGKAPPL_00180	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DHGKAPPL_00181	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DHGKAPPL_00182	1.04e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DHGKAPPL_00183	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DHGKAPPL_00184	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00185	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
DHGKAPPL_00186	3.9e-143	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DHGKAPPL_00187	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_00188	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
DHGKAPPL_00189	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
DHGKAPPL_00190	1.75e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
DHGKAPPL_00191	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
DHGKAPPL_00192	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00193	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
DHGKAPPL_00194	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DHGKAPPL_00195	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DHGKAPPL_00196	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DHGKAPPL_00197	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_00198	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
DHGKAPPL_00199	0.0	-	-	-	S	-	-	-	Putative metallopeptidase domain
DHGKAPPL_00200	1.03e-65	-	-	-	-	-	-	-	-
DHGKAPPL_00201	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
DHGKAPPL_00202	7.83e-60	-	-	-	-	-	-	-	-
DHGKAPPL_00203	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00204	2.48e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00205	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00206	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DHGKAPPL_00207	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DHGKAPPL_00208	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DHGKAPPL_00209	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DHGKAPPL_00210	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
DHGKAPPL_00211	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DHGKAPPL_00212	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DHGKAPPL_00213	1.01e-26	-	-	-	-	-	-	-	-
DHGKAPPL_00214	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
DHGKAPPL_00215	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
DHGKAPPL_00216	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_00217	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DHGKAPPL_00218	1.14e-231	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHGKAPPL_00219	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
DHGKAPPL_00220	2.41e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DHGKAPPL_00221	7.17e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DHGKAPPL_00222	1.72e-129	-	-	-	K	-	-	-	transcriptional regulator
DHGKAPPL_00223	3.79e-203	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
DHGKAPPL_00224	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
DHGKAPPL_00225	5.13e-138	-	-	-	-	-	-	-	-
DHGKAPPL_00227	5.77e-81	-	-	-	-	-	-	-	-
DHGKAPPL_00228	2.15e-71	-	-	-	-	-	-	-	-
DHGKAPPL_00229	1.44e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
DHGKAPPL_00230	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
DHGKAPPL_00231	4.45e-38	-	-	-	-	-	-	-	-
DHGKAPPL_00232	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
DHGKAPPL_00233	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00234	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DHGKAPPL_00235	4.66e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
DHGKAPPL_00236	3.86e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00237	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_00238	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_00239	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DHGKAPPL_00240	1.58e-66	-	-	-	-	-	-	-	-
DHGKAPPL_00241	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
DHGKAPPL_00242	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
DHGKAPPL_00243	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DHGKAPPL_00244	3.02e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DHGKAPPL_00245	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DHGKAPPL_00246	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
DHGKAPPL_00247	3.34e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
DHGKAPPL_00248	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DHGKAPPL_00249	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DHGKAPPL_00250	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
DHGKAPPL_00251	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DHGKAPPL_00252	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DHGKAPPL_00253	7.28e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHGKAPPL_00254	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DHGKAPPL_00255	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DHGKAPPL_00256	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
DHGKAPPL_00257	4.39e-66	-	-	-	-	-	-	-	-
DHGKAPPL_00258	7.21e-35	-	-	-	-	-	-	-	-
DHGKAPPL_00259	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DHGKAPPL_00260	2.07e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
DHGKAPPL_00261	4.26e-54	-	-	-	-	-	-	-	-
DHGKAPPL_00262	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DHGKAPPL_00263	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DHGKAPPL_00264	1.26e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
DHGKAPPL_00265	1.47e-144	-	-	-	S	-	-	-	VIT family
DHGKAPPL_00266	2.66e-155	-	-	-	S	-	-	-	membrane
DHGKAPPL_00267	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_00268	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
DHGKAPPL_00269	1.02e-149	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00270	4.79e-21	-	-	-	-	-	-	-	-
DHGKAPPL_00271	4.59e-74	-	-	-	-	-	-	-	-
DHGKAPPL_00272	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DHGKAPPL_00273	9.16e-111	-	-	-	-	-	-	-	-
DHGKAPPL_00274	2.11e-82	-	-	-	-	-	-	-	-
DHGKAPPL_00275	1.43e-274	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
DHGKAPPL_00276	1.7e-70	-	-	-	-	-	-	-	-
DHGKAPPL_00277	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DHGKAPPL_00278	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
DHGKAPPL_00279	4.31e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
DHGKAPPL_00280	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00281	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
DHGKAPPL_00282	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_00283	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHGKAPPL_00284	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DHGKAPPL_00285	1.5e-27	-	-	-	S	-	-	-	Belongs to the LOG family
DHGKAPPL_00286	1.01e-255	glmS2	-	-	M	-	-	-	SIS domain
DHGKAPPL_00287	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DHGKAPPL_00288	1.11e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DHGKAPPL_00289	2.82e-161	-	-	-	S	-	-	-	YjbR
DHGKAPPL_00291	0.0	cadA	-	-	P	-	-	-	P-type ATPase
DHGKAPPL_00292	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
DHGKAPPL_00293	1.46e-154	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHGKAPPL_00294	4.29e-101	-	-	-	-	-	-	-	-
DHGKAPPL_00295	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
DHGKAPPL_00296	2.42e-127	-	-	-	FG	-	-	-	HIT domain
DHGKAPPL_00297	7.39e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
DHGKAPPL_00298	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
DHGKAPPL_00299	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DHGKAPPL_00300	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
DHGKAPPL_00301	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
DHGKAPPL_00302	3.74e-125	-	-	-	V	-	-	-	VanZ like family
DHGKAPPL_00303	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DHGKAPPL_00304	4.54e-54	-	-	-	-	-	-	-	-
DHGKAPPL_00306	5.3e-316	-	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_00307	3.24e-215	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DHGKAPPL_00308	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
DHGKAPPL_00309	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DHGKAPPL_00310	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DHGKAPPL_00311	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
DHGKAPPL_00312	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DHGKAPPL_00313	4.4e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
DHGKAPPL_00314	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
DHGKAPPL_00315	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DHGKAPPL_00317	2.77e-30	-	-	-	-	-	-	-	-
DHGKAPPL_00319	1.63e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_00320	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DHGKAPPL_00321	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_00322	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DHGKAPPL_00323	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
DHGKAPPL_00324	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
DHGKAPPL_00325	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DHGKAPPL_00326	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
DHGKAPPL_00327	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHGKAPPL_00328	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DHGKAPPL_00330	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
DHGKAPPL_00331	1.88e-106	-	-	-	-	-	-	-	-
DHGKAPPL_00333	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHGKAPPL_00334	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DHGKAPPL_00335	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DHGKAPPL_00336	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DHGKAPPL_00337	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DHGKAPPL_00338	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
DHGKAPPL_00339	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DHGKAPPL_00340	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DHGKAPPL_00341	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHGKAPPL_00342	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
DHGKAPPL_00343	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
DHGKAPPL_00344	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
DHGKAPPL_00345	1.03e-34	-	-	-	-	-	-	-	-
DHGKAPPL_00346	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DHGKAPPL_00347	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
DHGKAPPL_00348	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
DHGKAPPL_00349	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_00350	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DHGKAPPL_00351	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
DHGKAPPL_00352	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
DHGKAPPL_00353	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DHGKAPPL_00354	3.32e-135	-	-	-	-	-	-	-	-
DHGKAPPL_00355	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
DHGKAPPL_00356	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHGKAPPL_00358	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
DHGKAPPL_00359	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00360	6.46e-201	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00361	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
DHGKAPPL_00362	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00363	1.03e-21	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
DHGKAPPL_00364	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_00365	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
DHGKAPPL_00366	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
DHGKAPPL_00367	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DHGKAPPL_00368	1.44e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DHGKAPPL_00369	1.14e-195	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
DHGKAPPL_00370	6.26e-101	-	-	-	-	-	-	-	-
DHGKAPPL_00371	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHGKAPPL_00372	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00373	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DHGKAPPL_00374	1.07e-262	-	-	-	S	-	-	-	DUF218 domain
DHGKAPPL_00375	6.39e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DHGKAPPL_00376	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DHGKAPPL_00377	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00378	2.48e-204	-	-	-	S	-	-	-	Putative adhesin
DHGKAPPL_00379	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
DHGKAPPL_00380	1.72e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00381	2.53e-126	-	-	-	KT	-	-	-	response to antibiotic
DHGKAPPL_00382	1.2e-175	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DHGKAPPL_00383	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00384	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00385	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DHGKAPPL_00386	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
DHGKAPPL_00387	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_00388	3.14e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_00389	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DHGKAPPL_00390	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
DHGKAPPL_00391	3.51e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DHGKAPPL_00392	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DHGKAPPL_00393	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
DHGKAPPL_00394	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DHGKAPPL_00395	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DHGKAPPL_00396	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DHGKAPPL_00397	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DHGKAPPL_00398	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DHGKAPPL_00399	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DHGKAPPL_00400	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DHGKAPPL_00401	1.14e-159	vanR	-	-	K	-	-	-	response regulator
DHGKAPPL_00402	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
DHGKAPPL_00403	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DHGKAPPL_00404	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DHGKAPPL_00405	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
DHGKAPPL_00406	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
DHGKAPPL_00407	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DHGKAPPL_00408	2.12e-72	-	-	-	-	-	-	-	-
DHGKAPPL_00409	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DHGKAPPL_00410	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
DHGKAPPL_00411	1.11e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
DHGKAPPL_00412	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
DHGKAPPL_00413	3.32e-210	-	-	-	-	-	-	-	-
DHGKAPPL_00414	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DHGKAPPL_00415	3.28e-147	-	-	-	-	-	-	-	-
DHGKAPPL_00416	2.66e-270	xylR	-	-	GK	-	-	-	ROK family
DHGKAPPL_00417	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
DHGKAPPL_00418	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DHGKAPPL_00419	6.79e-53	-	-	-	-	-	-	-	-
DHGKAPPL_00421	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
DHGKAPPL_00422	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
DHGKAPPL_00423	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00424	1.13e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
DHGKAPPL_00425	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
DHGKAPPL_00426	1.6e-103	-	-	-	GM	-	-	-	SnoaL-like domain
DHGKAPPL_00427	2.85e-141	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00428	4.71e-47	-	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
DHGKAPPL_00429	2.31e-132	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DHGKAPPL_00430	5.68e-155	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DHGKAPPL_00431	5.04e-92	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHGKAPPL_00432	3.2e-109	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHGKAPPL_00434	5.49e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DHGKAPPL_00435	1.68e-121	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
DHGKAPPL_00436	8.95e-53	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
DHGKAPPL_00437	1.4e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DHGKAPPL_00438	5.57e-141	yoaZ	-	-	S	-	-	-	intracellular protease amidase
DHGKAPPL_00439	7.29e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
DHGKAPPL_00440	2.73e-284	-	-	-	S	-	-	-	Membrane
DHGKAPPL_00441	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_00442	2.61e-64	sgaB	2.7.1.194, 2.7.1.200	-	G	ko:K02774,ko:K02822,ko:K03475	ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DHGKAPPL_00443	1.43e-307	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DHGKAPPL_00444	0.0	-	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHGKAPPL_00445	3.21e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DHGKAPPL_00446	0.0	-	-	-	G	ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757	ko00010,ko02060,map00010,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_00447	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00448	7.39e-189	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DHGKAPPL_00450	1.85e-41	-	-	-	-	-	-	-	-
DHGKAPPL_00451	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DHGKAPPL_00452	0.0	-	-	-	S	-	-	-	MucBP domain
DHGKAPPL_00453	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHGKAPPL_00454	9.5e-209	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_00455	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
DHGKAPPL_00456	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHGKAPPL_00457	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DHGKAPPL_00458	2.4e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00459	1.23e-268	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
DHGKAPPL_00460	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00461	4.88e-29	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_00462	3.51e-171	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_00463	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DHGKAPPL_00464	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_00465	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
DHGKAPPL_00466	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DHGKAPPL_00467	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00468	7.53e-208	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00469	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00470	1.35e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGKAPPL_00471	2.58e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGKAPPL_00472	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DHGKAPPL_00473	3.49e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
DHGKAPPL_00474	4.38e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00475	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
DHGKAPPL_00476	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
DHGKAPPL_00477	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DHGKAPPL_00478	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
DHGKAPPL_00479	6.76e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00480	3.27e-170	-	-	-	S	-	-	-	KR domain
DHGKAPPL_00481	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DHGKAPPL_00482	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
DHGKAPPL_00483	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DHGKAPPL_00484	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DHGKAPPL_00485	6.24e-215	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00486	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_00487	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DHGKAPPL_00488	8.01e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DHGKAPPL_00489	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DHGKAPPL_00490	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DHGKAPPL_00491	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_00492	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DHGKAPPL_00493	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DHGKAPPL_00494	4.13e-157	-	-	-	-	-	-	-	-
DHGKAPPL_00495	2.07e-311	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
DHGKAPPL_00496	1.47e-83	-	-	-	-	-	-	-	-
DHGKAPPL_00497	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00498	1.59e-243	ynjC	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00499	3.33e-149	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
DHGKAPPL_00500	1.22e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DHGKAPPL_00501	9.33e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
DHGKAPPL_00502	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00503	1.11e-240	-	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00504	1.56e-98	-	-	-	-	-	-	-	-
DHGKAPPL_00505	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_00506	4.34e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DHGKAPPL_00507	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
DHGKAPPL_00508	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_00509	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DHGKAPPL_00510	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
DHGKAPPL_00511	3.65e-59	-	-	-	S	-	-	-	Cupredoxin-like domain
DHGKAPPL_00512	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DHGKAPPL_00513	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
DHGKAPPL_00514	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
DHGKAPPL_00515	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
DHGKAPPL_00516	0.0	-	-	-	E	-	-	-	Amino Acid
DHGKAPPL_00517	1.74e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_00518	9.38e-91	-	-	-	-	-	-	-	-
DHGKAPPL_00520	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
DHGKAPPL_00521	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
DHGKAPPL_00522	1.3e-226	-	-	-	O	-	-	-	protein import
DHGKAPPL_00523	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00524	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00525	2.31e-277	-	-	-	-	-	-	-	-
DHGKAPPL_00526	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00527	4.19e-70	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
DHGKAPPL_00528	3.3e-87	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
DHGKAPPL_00529	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
DHGKAPPL_00530	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
DHGKAPPL_00531	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DHGKAPPL_00532	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00533	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
DHGKAPPL_00534	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00535	3.05e-95	-	-	-	-	-	-	-	-
DHGKAPPL_00536	2.02e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
DHGKAPPL_00537	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
DHGKAPPL_00538	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DHGKAPPL_00539	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
DHGKAPPL_00540	2.72e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
DHGKAPPL_00541	2.06e-119	-	-	-	-	-	-	-	-
DHGKAPPL_00542	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DHGKAPPL_00543	1.58e-72	nudA	-	-	S	-	-	-	ASCH
DHGKAPPL_00544	9.47e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
DHGKAPPL_00545	1.44e-128	-	-	-	M	-	-	-	Lysin motif
DHGKAPPL_00546	4.61e-101	-	-	-	M	-	-	-	LysM domain
DHGKAPPL_00547	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_00548	1.57e-237	-	-	-	GM	-	-	-	Male sterility protein
DHGKAPPL_00549	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00550	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_00551	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_00552	2.75e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DHGKAPPL_00553	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_00554	1.21e-73	-	-	-	-	-	-	-	-
DHGKAPPL_00555	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DHGKAPPL_00556	2.03e-84	-	-	-	-	-	-	-	-
DHGKAPPL_00557	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
DHGKAPPL_00558	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00559	2.26e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
DHGKAPPL_00560	3.36e-62	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DHGKAPPL_00561	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
DHGKAPPL_00562	7.03e-62	-	-	-	-	-	-	-	-
DHGKAPPL_00563	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHGKAPPL_00564	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DHGKAPPL_00565	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_00566	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
DHGKAPPL_00567	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
DHGKAPPL_00568	1.15e-43	-	-	-	-	-	-	-	-
DHGKAPPL_00570	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
DHGKAPPL_00571	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DHGKAPPL_00572	3.79e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
DHGKAPPL_00573	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
DHGKAPPL_00574	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00575	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
DHGKAPPL_00576	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_00577	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
DHGKAPPL_00578	3.08e-80	-	-	-	-	-	-	-	-
DHGKAPPL_00579	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_00580	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_00581	2.76e-196	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DHGKAPPL_00582	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DHGKAPPL_00583	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DHGKAPPL_00584	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
DHGKAPPL_00585	6.37e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DHGKAPPL_00586	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DHGKAPPL_00587	9.16e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DHGKAPPL_00588	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DHGKAPPL_00589	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
DHGKAPPL_00590	2.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
DHGKAPPL_00591	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DHGKAPPL_00592	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_00593	1.99e-297	-	-	-	M	-	-	-	Collagen binding domain
DHGKAPPL_00594	0.0	-	-	-	I	-	-	-	acetylesterase activity
DHGKAPPL_00595	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DHGKAPPL_00596	2.78e-176	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
DHGKAPPL_00597	4.29e-50	-	-	-	-	-	-	-	-
DHGKAPPL_00599	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
DHGKAPPL_00600	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DHGKAPPL_00601	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DHGKAPPL_00602	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
DHGKAPPL_00603	2.09e-211	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_00604	3.06e-62	-	-	-	-	-	-	-	-
DHGKAPPL_00605	3.33e-76	-	-	-	-	-	-	-	-
DHGKAPPL_00606	3.7e-30	-	-	-	-	-	-	-	-
DHGKAPPL_00607	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHGKAPPL_00608	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DHGKAPPL_00609	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DHGKAPPL_00610	1.56e-108	-	-	-	-	-	-	-	-
DHGKAPPL_00611	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DHGKAPPL_00612	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DHGKAPPL_00613	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DHGKAPPL_00614	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
DHGKAPPL_00615	3.54e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DHGKAPPL_00616	2e-52	-	-	-	S	-	-	-	Cytochrome B5
DHGKAPPL_00617	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_00618	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DHGKAPPL_00619	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHGKAPPL_00620	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
DHGKAPPL_00621	2.06e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
DHGKAPPL_00622	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_00623	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DHGKAPPL_00624	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
DHGKAPPL_00625	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
DHGKAPPL_00626	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DHGKAPPL_00627	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DHGKAPPL_00628	1.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_00629	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DHGKAPPL_00630	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_00631	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DHGKAPPL_00632	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_00633	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
DHGKAPPL_00634	1.58e-230	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DHGKAPPL_00637	9.09e-314	-	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_00638	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00639	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_00641	4.96e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
DHGKAPPL_00642	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
DHGKAPPL_00643	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DHGKAPPL_00644	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DHGKAPPL_00645	1.12e-105	-	-	-	-	-	-	-	-
DHGKAPPL_00646	1.19e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DHGKAPPL_00647	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DHGKAPPL_00648	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHGKAPPL_00649	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00650	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DHGKAPPL_00651	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DHGKAPPL_00652	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
DHGKAPPL_00653	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00654	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_00655	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
DHGKAPPL_00657	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00658	2.11e-132	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DHGKAPPL_00659	7.8e-113	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00660	1.43e-114	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DHGKAPPL_00661	2.78e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
DHGKAPPL_00662	3.71e-99	-	-	-	C	-	-	-	Flavodoxin
DHGKAPPL_00663	4.83e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DHGKAPPL_00664	1.4e-180	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DHGKAPPL_00665	5.85e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
DHGKAPPL_00666	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHGKAPPL_00667	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00668	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_00669	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
DHGKAPPL_00670	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
DHGKAPPL_00671	2.81e-64	-	-	-	-	-	-	-	-
DHGKAPPL_00672	2.8e-49	-	-	-	-	-	-	-	-
DHGKAPPL_00673	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
DHGKAPPL_00674	2.82e-110	-	-	-	-	-	-	-	-
DHGKAPPL_00675	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DHGKAPPL_00676	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHGKAPPL_00677	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DHGKAPPL_00679	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00680	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DHGKAPPL_00681	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DHGKAPPL_00682	7.37e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
DHGKAPPL_00683	7.92e-99	yphH	-	-	S	-	-	-	Cupin domain
DHGKAPPL_00684	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
DHGKAPPL_00685	2.53e-24	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00686	9.81e-127	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00687	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DHGKAPPL_00688	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00689	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
DHGKAPPL_00690	2.72e-90	-	-	-	M	-	-	-	LysM domain
DHGKAPPL_00692	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHGKAPPL_00693	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
DHGKAPPL_00694	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_00695	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DHGKAPPL_00696	7.69e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DHGKAPPL_00697	5.97e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DHGKAPPL_00698	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHGKAPPL_00699	4.35e-164	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DHGKAPPL_00700	3.46e-251	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_00701	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
DHGKAPPL_00702	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DHGKAPPL_00703	9.01e-155	-	-	-	S	-	-	-	Membrane
DHGKAPPL_00704	1.97e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DHGKAPPL_00705	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
DHGKAPPL_00706	4.7e-237	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
DHGKAPPL_00707	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
DHGKAPPL_00708	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00709	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DHGKAPPL_00710	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DHGKAPPL_00711	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHGKAPPL_00712	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_00713	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DHGKAPPL_00714	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DHGKAPPL_00715	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
DHGKAPPL_00716	2.94e-227	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DHGKAPPL_00717	1.54e-144	-	-	-	-	-	-	-	-
DHGKAPPL_00718	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DHGKAPPL_00719	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
DHGKAPPL_00720	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DHGKAPPL_00722	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00723	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DHGKAPPL_00724	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
DHGKAPPL_00725	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DHGKAPPL_00726	0.0	ycaM	-	-	E	-	-	-	amino acid
DHGKAPPL_00727	2.89e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
DHGKAPPL_00728	4.3e-44	-	-	-	-	-	-	-	-
DHGKAPPL_00729	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
DHGKAPPL_00730	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DHGKAPPL_00731	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DHGKAPPL_00732	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
DHGKAPPL_00733	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DHGKAPPL_00734	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DHGKAPPL_00735	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_00736	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHGKAPPL_00737	5.06e-196	-	-	-	S	-	-	-	hydrolase
DHGKAPPL_00738	7.63e-107	-	-	-	-	-	-	-	-
DHGKAPPL_00739	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
DHGKAPPL_00740	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
DHGKAPPL_00741	2.6e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DHGKAPPL_00742	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_00743	2.73e-73	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
DHGKAPPL_00744	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00745	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_00746	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
DHGKAPPL_00747	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DHGKAPPL_00748	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_00749	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00750	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHGKAPPL_00751	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
DHGKAPPL_00752	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
DHGKAPPL_00753	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DHGKAPPL_00754	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
DHGKAPPL_00755	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DHGKAPPL_00756	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
DHGKAPPL_00757	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
DHGKAPPL_00758	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHGKAPPL_00759	2.38e-37	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
DHGKAPPL_00760	1.1e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_00761	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DHGKAPPL_00762	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DHGKAPPL_00764	1.21e-69	-	-	-	-	-	-	-	-
DHGKAPPL_00765	1.52e-151	-	-	-	-	-	-	-	-
DHGKAPPL_00766	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
DHGKAPPL_00767	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DHGKAPPL_00768	4.79e-13	-	-	-	-	-	-	-	-
DHGKAPPL_00769	1.4e-65	-	-	-	-	-	-	-	-
DHGKAPPL_00770	1.76e-114	-	-	-	-	-	-	-	-
DHGKAPPL_00771	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
DHGKAPPL_00772	1.08e-47	-	-	-	-	-	-	-	-
DHGKAPPL_00773	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
DHGKAPPL_00774	5.66e-189	-	-	-	-	-	-	-	-
DHGKAPPL_00775	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00776	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
DHGKAPPL_00777	4.76e-56	-	-	-	-	-	-	-	-
DHGKAPPL_00778	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DHGKAPPL_00779	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00780	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
DHGKAPPL_00781	9.78e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_00782	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DHGKAPPL_00783	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DHGKAPPL_00784	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
DHGKAPPL_00785	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHGKAPPL_00786	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DHGKAPPL_00787	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DHGKAPPL_00788	5.8e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DHGKAPPL_00789	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DHGKAPPL_00790	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGKAPPL_00791	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGKAPPL_00792	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGKAPPL_00793	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DHGKAPPL_00794	1.04e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DHGKAPPL_00795	1.79e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DHGKAPPL_00796	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DHGKAPPL_00797	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DHGKAPPL_00798	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
DHGKAPPL_00799	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
DHGKAPPL_00800	1.85e-121	-	-	-	-	-	-	-	-
DHGKAPPL_00801	1.46e-198	-	-	-	T	-	-	-	EAL domain
DHGKAPPL_00802	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_00803	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
DHGKAPPL_00804	4.41e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DHGKAPPL_00805	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
DHGKAPPL_00806	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DHGKAPPL_00807	1.42e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DHGKAPPL_00808	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DHGKAPPL_00809	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DHGKAPPL_00810	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHGKAPPL_00811	4.24e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DHGKAPPL_00812	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DHGKAPPL_00813	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DHGKAPPL_00814	4.54e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
DHGKAPPL_00815	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DHGKAPPL_00816	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DHGKAPPL_00817	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DHGKAPPL_00818	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_00819	5.73e-208	mleR	-	-	K	-	-	-	LysR family
DHGKAPPL_00820	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DHGKAPPL_00821	3.59e-26	-	-	-	-	-	-	-	-
DHGKAPPL_00822	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHGKAPPL_00823	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHGKAPPL_00824	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
DHGKAPPL_00825	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DHGKAPPL_00826	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
DHGKAPPL_00827	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DHGKAPPL_00828	8.13e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_00829	3.36e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_00830	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHGKAPPL_00831	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DHGKAPPL_00832	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DHGKAPPL_00833	2.97e-76	-	-	-	-	-	-	-	-
DHGKAPPL_00834	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DHGKAPPL_00835	1.55e-79	-	-	-	-	-	-	-	-
DHGKAPPL_00836	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DHGKAPPL_00837	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
DHGKAPPL_00838	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHGKAPPL_00839	1.18e-176	-	-	-	-	-	-	-	-
DHGKAPPL_00840	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DHGKAPPL_00841	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00842	2.25e-206	-	-	-	S	-	-	-	Putative esterase
DHGKAPPL_00843	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DHGKAPPL_00844	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
DHGKAPPL_00845	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DHGKAPPL_00846	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DHGKAPPL_00847	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DHGKAPPL_00848	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
DHGKAPPL_00849	2.73e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00850	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DHGKAPPL_00851	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
DHGKAPPL_00852	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
DHGKAPPL_00853	2.46e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DHGKAPPL_00854	8.37e-78	-	-	-	-	-	-	-	-
DHGKAPPL_00855	4.05e-98	-	-	-	-	-	-	-	-
DHGKAPPL_00856	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
DHGKAPPL_00857	2.16e-63	-	-	-	-	-	-	-	-
DHGKAPPL_00858	3.89e-62	-	-	-	-	-	-	-	-
DHGKAPPL_00859	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DHGKAPPL_00860	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
DHGKAPPL_00861	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
DHGKAPPL_00862	1.17e-88	-	-	-	-	-	-	-	-
DHGKAPPL_00863	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_00864	4.83e-64	-	-	-	-	-	-	-	-
DHGKAPPL_00865	1.23e-75	-	-	-	-	-	-	-	-
DHGKAPPL_00866	1.86e-210	-	-	-	-	-	-	-	-
DHGKAPPL_00867	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_00868	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
DHGKAPPL_00869	2.29e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHGKAPPL_00870	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
DHGKAPPL_00871	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
DHGKAPPL_00872	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_00873	2.66e-172	-	-	-	-	-	-	-	-
DHGKAPPL_00874	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
DHGKAPPL_00875	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DHGKAPPL_00876	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHGKAPPL_00877	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
DHGKAPPL_00878	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DHGKAPPL_00879	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DHGKAPPL_00880	1.22e-200	ccpB	-	-	K	-	-	-	lacI family
DHGKAPPL_00881	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_00882	4.21e-210	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHGKAPPL_00883	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
DHGKAPPL_00884	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
DHGKAPPL_00885	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
DHGKAPPL_00886	8.69e-247	-	-	-	S	-	-	-	domain, Protein
DHGKAPPL_00887	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_00888	1.63e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DHGKAPPL_00889	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DHGKAPPL_00890	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DHGKAPPL_00891	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_00892	0.0	-	-	-	M	-	-	-	domain protein
DHGKAPPL_00893	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DHGKAPPL_00894	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DHGKAPPL_00895	1.45e-46	-	-	-	-	-	-	-	-
DHGKAPPL_00896	1.15e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHGKAPPL_00897	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DHGKAPPL_00898	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
DHGKAPPL_00899	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_00900	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
DHGKAPPL_00901	1.11e-72	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
DHGKAPPL_00902	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DHGKAPPL_00903	2.15e-282	ysaA	-	-	V	-	-	-	RDD family
DHGKAPPL_00904	1.12e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
DHGKAPPL_00905	3.81e-274	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DHGKAPPL_00906	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DHGKAPPL_00907	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DHGKAPPL_00908	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
DHGKAPPL_00909	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DHGKAPPL_00910	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DHGKAPPL_00911	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHGKAPPL_00912	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DHGKAPPL_00913	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
DHGKAPPL_00914	2.9e-253	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DHGKAPPL_00915	6.8e-123	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHGKAPPL_00916	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
DHGKAPPL_00917	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DHGKAPPL_00918	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DHGKAPPL_00919	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00920	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DHGKAPPL_00921	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_00922	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DHGKAPPL_00923	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
DHGKAPPL_00924	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DHGKAPPL_00925	5.97e-210	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DHGKAPPL_00926	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHGKAPPL_00927	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DHGKAPPL_00928	9.2e-62	-	-	-	-	-	-	-	-
DHGKAPPL_00929	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGKAPPL_00930	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
DHGKAPPL_00931	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DHGKAPPL_00932	2.12e-273	-	-	-	T	-	-	-	diguanylate cyclase
DHGKAPPL_00933	1.11e-45	-	-	-	-	-	-	-	-
DHGKAPPL_00934	2.29e-48	-	-	-	-	-	-	-	-
DHGKAPPL_00935	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
DHGKAPPL_00936	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
DHGKAPPL_00937	3.88e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_00939	2.68e-32	-	-	-	-	-	-	-	-
DHGKAPPL_00940	1.9e-176	-	-	-	F	-	-	-	NUDIX domain
DHGKAPPL_00941	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
DHGKAPPL_00942	7.59e-64	-	-	-	-	-	-	-	-
DHGKAPPL_00943	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DHGKAPPL_00945	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_00946	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DHGKAPPL_00947	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DHGKAPPL_00948	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DHGKAPPL_00949	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DHGKAPPL_00950	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
DHGKAPPL_00951	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DHGKAPPL_00952	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DHGKAPPL_00953	2.1e-33	-	-	-	-	-	-	-	-
DHGKAPPL_00954	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00955	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHGKAPPL_00956	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
DHGKAPPL_00957	4.63e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00958	2.16e-26	-	-	-	-	-	-	-	-
DHGKAPPL_00959	9.35e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00960	2.69e-23	-	-	-	-	-	-	-	-
DHGKAPPL_00961	9.35e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00962	1.07e-26	-	-	-	-	-	-	-	-
DHGKAPPL_00963	1.56e-22	-	-	-	-	-	-	-	-
DHGKAPPL_00964	3.26e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00965	6.58e-24	-	-	-	-	-	-	-	-
DHGKAPPL_00966	0.0	inlJ	-	-	M	-	-	-	MucBP domain
DHGKAPPL_00967	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
DHGKAPPL_00968	1.27e-109	-	-	-	K	-	-	-	MarR family
DHGKAPPL_00969	9.28e-58	-	-	-	-	-	-	-	-
DHGKAPPL_00970	1.28e-51	-	-	-	-	-	-	-	-
DHGKAPPL_00972	1.98e-40	-	-	-	-	-	-	-	-
DHGKAPPL_00975	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
DHGKAPPL_00976	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
DHGKAPPL_00977	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_00978	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DHGKAPPL_00979	5.37e-182	-	-	-	-	-	-	-	-
DHGKAPPL_00980	1.33e-77	-	-	-	-	-	-	-	-
DHGKAPPL_00981	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DHGKAPPL_00982	8.57e-41	-	-	-	-	-	-	-	-
DHGKAPPL_00983	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
DHGKAPPL_00984	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DHGKAPPL_00985	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
DHGKAPPL_00986	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
DHGKAPPL_00987	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DHGKAPPL_00988	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DHGKAPPL_00989	6.95e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DHGKAPPL_00990	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DHGKAPPL_00991	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DHGKAPPL_00992	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DHGKAPPL_00993	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DHGKAPPL_00994	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DHGKAPPL_00995	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHGKAPPL_00996	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DHGKAPPL_00997	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHGKAPPL_00998	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DHGKAPPL_00999	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DHGKAPPL_01000	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DHGKAPPL_01001	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DHGKAPPL_01002	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHGKAPPL_01003	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DHGKAPPL_01004	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DHGKAPPL_01005	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
DHGKAPPL_01006	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DHGKAPPL_01007	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DHGKAPPL_01008	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
DHGKAPPL_01009	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHGKAPPL_01010	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01011	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DHGKAPPL_01012	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHGKAPPL_01013	1.81e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DHGKAPPL_01014	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DHGKAPPL_01015	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DHGKAPPL_01016	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
DHGKAPPL_01017	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_01018	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DHGKAPPL_01019	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
DHGKAPPL_01020	1.34e-52	-	-	-	-	-	-	-	-
DHGKAPPL_01021	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DHGKAPPL_01022	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DHGKAPPL_01023	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
DHGKAPPL_01024	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DHGKAPPL_01025	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DHGKAPPL_01026	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
DHGKAPPL_01027	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DHGKAPPL_01028	3.95e-288	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
DHGKAPPL_01029	5.51e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_01030	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
DHGKAPPL_01031	1.2e-106	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DHGKAPPL_01032	3.73e-150	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
DHGKAPPL_01033	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DHGKAPPL_01034	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DHGKAPPL_01035	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DHGKAPPL_01036	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DHGKAPPL_01037	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DHGKAPPL_01038	5.71e-302	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
DHGKAPPL_01039	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DHGKAPPL_01040	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DHGKAPPL_01041	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DHGKAPPL_01042	1.35e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DHGKAPPL_01043	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DHGKAPPL_01044	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DHGKAPPL_01045	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DHGKAPPL_01046	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DHGKAPPL_01047	3.54e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
DHGKAPPL_01048	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01049	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01050	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DHGKAPPL_01051	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DHGKAPPL_01052	7.16e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DHGKAPPL_01053	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
DHGKAPPL_01054	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
DHGKAPPL_01055	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHGKAPPL_01056	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DHGKAPPL_01057	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DHGKAPPL_01058	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DHGKAPPL_01059	2.52e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
DHGKAPPL_01060	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DHGKAPPL_01061	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DHGKAPPL_01062	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_01063	7.81e-93	-	-	-	-	-	-	-	-
DHGKAPPL_01064	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DHGKAPPL_01065	1.25e-119	-	-	-	-	-	-	-	-
DHGKAPPL_01066	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DHGKAPPL_01067	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DHGKAPPL_01068	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DHGKAPPL_01069	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DHGKAPPL_01070	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DHGKAPPL_01071	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DHGKAPPL_01072	4.12e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DHGKAPPL_01073	1.86e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DHGKAPPL_01074	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DHGKAPPL_01075	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DHGKAPPL_01076	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DHGKAPPL_01077	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DHGKAPPL_01078	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DHGKAPPL_01079	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DHGKAPPL_01080	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DHGKAPPL_01081	2.57e-118	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DHGKAPPL_01082	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DHGKAPPL_01083	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DHGKAPPL_01084	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DHGKAPPL_01085	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
DHGKAPPL_01086	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DHGKAPPL_01087	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DHGKAPPL_01088	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DHGKAPPL_01089	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DHGKAPPL_01090	1.6e-96	-	-	-	-	-	-	-	-
DHGKAPPL_01091	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_01092	5.18e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DHGKAPPL_01093	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DHGKAPPL_01094	4.56e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DHGKAPPL_01095	2.34e-63	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
DHGKAPPL_01096	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DHGKAPPL_01097	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHGKAPPL_01098	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DHGKAPPL_01099	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DHGKAPPL_01100	5.66e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
DHGKAPPL_01101	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
DHGKAPPL_01102	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
DHGKAPPL_01103	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
DHGKAPPL_01105	2.22e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DHGKAPPL_01106	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHGKAPPL_01107	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHGKAPPL_01108	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DHGKAPPL_01109	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DHGKAPPL_01110	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DHGKAPPL_01111	2.92e-188	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DHGKAPPL_01112	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DHGKAPPL_01113	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_01114	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DHGKAPPL_01115	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHGKAPPL_01116	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
DHGKAPPL_01117	4.51e-84	-	-	-	-	-	-	-	-
DHGKAPPL_01118	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DHGKAPPL_01140	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
DHGKAPPL_01141	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DHGKAPPL_01142	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DHGKAPPL_01143	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DHGKAPPL_01144	3.19e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DHGKAPPL_01145	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DHGKAPPL_01146	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
DHGKAPPL_01147	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DHGKAPPL_01148	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DHGKAPPL_01149	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHGKAPPL_01150	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
DHGKAPPL_01151	6.5e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DHGKAPPL_01152	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DHGKAPPL_01153	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
DHGKAPPL_01154	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHGKAPPL_01155	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DHGKAPPL_01157	8.82e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DHGKAPPL_01158	1.76e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DHGKAPPL_01159	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DHGKAPPL_01160	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DHGKAPPL_01161	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DHGKAPPL_01162	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
DHGKAPPL_01163	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DHGKAPPL_01164	2.58e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DHGKAPPL_01165	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DHGKAPPL_01166	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DHGKAPPL_01167	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DHGKAPPL_01168	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DHGKAPPL_01169	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DHGKAPPL_01170	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DHGKAPPL_01171	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DHGKAPPL_01172	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DHGKAPPL_01173	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DHGKAPPL_01174	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DHGKAPPL_01175	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
DHGKAPPL_01176	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DHGKAPPL_01177	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DHGKAPPL_01178	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DHGKAPPL_01179	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DHGKAPPL_01180	7.74e-47	-	-	-	-	-	-	-	-
DHGKAPPL_01181	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DHGKAPPL_01182	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DHGKAPPL_01183	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DHGKAPPL_01184	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DHGKAPPL_01185	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
DHGKAPPL_01186	9.37e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
DHGKAPPL_01187	5.92e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_01188	2.25e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_01189	2.04e-139	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
DHGKAPPL_01190	0.0	-	-	-	N	-	-	-	domain, Protein
DHGKAPPL_01191	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DHGKAPPL_01192	1.02e-155	-	-	-	S	-	-	-	repeat protein
DHGKAPPL_01193	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DHGKAPPL_01194	1.6e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHGKAPPL_01195	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_01196	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DHGKAPPL_01197	1.21e-259	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DHGKAPPL_01198	6.21e-39	-	-	-	-	-	-	-	-
DHGKAPPL_01199	2.43e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DHGKAPPL_01200	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHGKAPPL_01201	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DHGKAPPL_01202	6.45e-111	-	-	-	-	-	-	-	-
DHGKAPPL_01203	2.29e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHGKAPPL_01204	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DHGKAPPL_01205	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DHGKAPPL_01206	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DHGKAPPL_01207	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DHGKAPPL_01208	1.24e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
DHGKAPPL_01209	6.24e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DHGKAPPL_01210	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DHGKAPPL_01211	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DHGKAPPL_01212	6.34e-257	-	-	-	-	-	-	-	-
DHGKAPPL_01213	3.18e-133	-	-	-	-	-	-	-	-
DHGKAPPL_01214	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
DHGKAPPL_01215	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_01216	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DHGKAPPL_01217	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DHGKAPPL_01218	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DHGKAPPL_01219	6.06e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DHGKAPPL_01220	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DHGKAPPL_01221	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DHGKAPPL_01222	3.85e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DHGKAPPL_01223	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DHGKAPPL_01224	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DHGKAPPL_01225	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DHGKAPPL_01226	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DHGKAPPL_01227	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DHGKAPPL_01228	1.82e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_01229	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHGKAPPL_01230	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHGKAPPL_01231	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
DHGKAPPL_01232	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DHGKAPPL_01233	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DHGKAPPL_01234	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DHGKAPPL_01235	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DHGKAPPL_01236	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DHGKAPPL_01237	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DHGKAPPL_01238	5.12e-31	-	-	-	-	-	-	-	-
DHGKAPPL_01239	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01240	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01241	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DHGKAPPL_01242	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
DHGKAPPL_01243	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DHGKAPPL_01244	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DHGKAPPL_01245	1.62e-228	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DHGKAPPL_01246	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
DHGKAPPL_01247	5.69e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
DHGKAPPL_01248	1.99e-237	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
DHGKAPPL_01249	3.68e-295	-	-	-	-	-	-	-	-
DHGKAPPL_01250	9.73e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
DHGKAPPL_01251	0.0	cps4J	-	-	S	-	-	-	MatE
DHGKAPPL_01252	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DHGKAPPL_01253	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
DHGKAPPL_01254	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DHGKAPPL_01255	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
DHGKAPPL_01256	1.81e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DHGKAPPL_01257	6.62e-62	-	-	-	-	-	-	-	-
DHGKAPPL_01258	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DHGKAPPL_01259	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_01260	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
DHGKAPPL_01261	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DHGKAPPL_01262	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DHGKAPPL_01263	7.9e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_01264	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DHGKAPPL_01265	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DHGKAPPL_01266	1.14e-180	-	-	-	Q	-	-	-	Methyltransferase
DHGKAPPL_01267	1.75e-43	-	-	-	-	-	-	-	-
DHGKAPPL_01270	1.54e-50	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHGKAPPL_01271	1.01e-42	-	-	-	L	ko:K07483	-	ko00000	transposase activity
DHGKAPPL_01272	2.14e-53	-	-	-	L	-	-	-	HTH-like domain
DHGKAPPL_01273	5.48e-05	-	-	-	S	-	-	-	Short C-terminal domain
DHGKAPPL_01274	5.59e-21	-	-	-	S	-	-	-	Short C-terminal domain
DHGKAPPL_01275	3.53e-09	-	-	-	S	-	-	-	Short C-terminal domain
DHGKAPPL_01278	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
DHGKAPPL_01279	2.68e-87	-	-	-	-	-	-	-	-
DHGKAPPL_01280	1.01e-100	-	-	-	-	-	-	-	-
DHGKAPPL_01281	6.62e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DHGKAPPL_01282	1.83e-121	-	-	-	-	-	-	-	-
DHGKAPPL_01283	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DHGKAPPL_01284	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
DHGKAPPL_01285	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DHGKAPPL_01286	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DHGKAPPL_01287	2.87e-169	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DHGKAPPL_01288	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DHGKAPPL_01289	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGKAPPL_01290	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
DHGKAPPL_01291	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DHGKAPPL_01292	1.55e-193	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DHGKAPPL_01293	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DHGKAPPL_01294	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DHGKAPPL_01295	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DHGKAPPL_01296	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DHGKAPPL_01297	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DHGKAPPL_01298	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DHGKAPPL_01299	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHGKAPPL_01300	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DHGKAPPL_01301	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DHGKAPPL_01302	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DHGKAPPL_01303	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
DHGKAPPL_01304	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DHGKAPPL_01305	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DHGKAPPL_01306	0.0	-	-	-	G	-	-	-	Major Facilitator
DHGKAPPL_01307	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DHGKAPPL_01308	6.65e-121	-	-	-	-	-	-	-	-
DHGKAPPL_01309	6.72e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DHGKAPPL_01310	5.99e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
DHGKAPPL_01311	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DHGKAPPL_01312	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DHGKAPPL_01313	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DHGKAPPL_01314	9.78e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
DHGKAPPL_01315	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DHGKAPPL_01316	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DHGKAPPL_01317	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DHGKAPPL_01318	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DHGKAPPL_01319	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
DHGKAPPL_01320	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DHGKAPPL_01321	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGKAPPL_01322	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DHGKAPPL_01323	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGKAPPL_01324	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DHGKAPPL_01325	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DHGKAPPL_01326	1.73e-67	-	-	-	-	-	-	-	-
DHGKAPPL_01327	4.78e-65	-	-	-	-	-	-	-	-
DHGKAPPL_01328	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DHGKAPPL_01329	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DHGKAPPL_01330	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DHGKAPPL_01331	2.56e-76	-	-	-	-	-	-	-	-
DHGKAPPL_01332	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DHGKAPPL_01333	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DHGKAPPL_01334	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
DHGKAPPL_01335	2.65e-213	-	-	-	G	-	-	-	Fructosamine kinase
DHGKAPPL_01336	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
DHGKAPPL_01337	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DHGKAPPL_01338	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DHGKAPPL_01339	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHGKAPPL_01340	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DHGKAPPL_01341	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DHGKAPPL_01342	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DHGKAPPL_01343	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
DHGKAPPL_01344	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DHGKAPPL_01345	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DHGKAPPL_01346	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DHGKAPPL_01347	9.71e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DHGKAPPL_01348	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DHGKAPPL_01349	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DHGKAPPL_01350	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DHGKAPPL_01351	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DHGKAPPL_01352	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DHGKAPPL_01353	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DHGKAPPL_01354	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DHGKAPPL_01355	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DHGKAPPL_01356	6.86e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DHGKAPPL_01357	2.01e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01358	5.01e-254	-	-	-	-	-	-	-	-
DHGKAPPL_01359	2.48e-252	-	-	-	-	-	-	-	-
DHGKAPPL_01360	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DHGKAPPL_01361	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01362	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DHGKAPPL_01363	4.27e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHGKAPPL_01364	3.89e-94	-	-	-	K	-	-	-	MarR family
DHGKAPPL_01365	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DHGKAPPL_01367	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_01368	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
DHGKAPPL_01369	2.08e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHGKAPPL_01370	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
DHGKAPPL_01371	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DHGKAPPL_01373	2.66e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DHGKAPPL_01374	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01375	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
DHGKAPPL_01376	3.55e-146	-	-	-	GM	-	-	-	NmrA-like family
DHGKAPPL_01377	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
DHGKAPPL_01378	3.69e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DHGKAPPL_01379	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DHGKAPPL_01380	7.51e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
DHGKAPPL_01381	8.34e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_01382	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_01383	1.55e-07	-	-	-	K	-	-	-	transcriptional regulator
DHGKAPPL_01384	1.12e-273	-	-	-	S	-	-	-	membrane
DHGKAPPL_01385	4.31e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_01386	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
DHGKAPPL_01387	5.7e-146	-	-	-	GM	-	-	-	epimerase
DHGKAPPL_01388	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
DHGKAPPL_01389	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
DHGKAPPL_01390	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DHGKAPPL_01391	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
DHGKAPPL_01392	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DHGKAPPL_01393	6.66e-235	tanA	-	-	S	-	-	-	alpha beta
DHGKAPPL_01394	6.46e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DHGKAPPL_01395	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01396	2.18e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
DHGKAPPL_01397	4.44e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHGKAPPL_01398	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DHGKAPPL_01399	5.25e-233	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DHGKAPPL_01400	6.08e-277	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DHGKAPPL_01401	1.07e-263	-	-	-	-	-	-	-	-
DHGKAPPL_01402	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_01403	1.94e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
DHGKAPPL_01404	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
DHGKAPPL_01405	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_01406	5.71e-211	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_01407	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
DHGKAPPL_01408	4.8e-293	-	-	-	M	-	-	-	O-Antigen ligase
DHGKAPPL_01409	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DHGKAPPL_01410	3.11e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DHGKAPPL_01411	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DHGKAPPL_01412	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DHGKAPPL_01414	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DHGKAPPL_01415	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DHGKAPPL_01416	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DHGKAPPL_01417	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DHGKAPPL_01418	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
DHGKAPPL_01419	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DHGKAPPL_01420	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DHGKAPPL_01421	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGKAPPL_01422	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DHGKAPPL_01423	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DHGKAPPL_01424	1.1e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DHGKAPPL_01425	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DHGKAPPL_01426	5.38e-249	-	-	-	S	-	-	-	Helix-turn-helix domain
DHGKAPPL_01427	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DHGKAPPL_01428	5.45e-38	-	-	-	M	-	-	-	Lysin motif
DHGKAPPL_01429	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DHGKAPPL_01430	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DHGKAPPL_01431	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DHGKAPPL_01432	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DHGKAPPL_01433	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DHGKAPPL_01434	3.71e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DHGKAPPL_01435	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DHGKAPPL_01436	1.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DHGKAPPL_01437	6.46e-109	-	-	-	-	-	-	-	-
DHGKAPPL_01438	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01439	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DHGKAPPL_01440	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DHGKAPPL_01441	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DHGKAPPL_01442	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DHGKAPPL_01443	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DHGKAPPL_01444	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DHGKAPPL_01445	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
DHGKAPPL_01446	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_01447	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
DHGKAPPL_01448	1.75e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DHGKAPPL_01449	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
DHGKAPPL_01450	1.22e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
DHGKAPPL_01451	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
DHGKAPPL_01452	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DHGKAPPL_01453	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHGKAPPL_01454	1.91e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DHGKAPPL_01455	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DHGKAPPL_01456	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DHGKAPPL_01457	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
DHGKAPPL_01458	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DHGKAPPL_01459	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DHGKAPPL_01460	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DHGKAPPL_01461	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DHGKAPPL_01462	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHGKAPPL_01463	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHGKAPPL_01464	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01465	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DHGKAPPL_01466	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DHGKAPPL_01467	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHGKAPPL_01468	1.26e-42	-	-	-	S	-	-	-	YozE SAM-like fold
DHGKAPPL_01469	5.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DHGKAPPL_01470	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHGKAPPL_01471	2.78e-309	-	-	-	M	-	-	-	Glycosyl transferase family group 2
DHGKAPPL_01472	3.81e-64	-	-	-	-	-	-	-	-
DHGKAPPL_01473	7.91e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DHGKAPPL_01474	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_01475	1.34e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DHGKAPPL_01476	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DHGKAPPL_01477	1.66e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DHGKAPPL_01478	1.47e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
DHGKAPPL_01479	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
DHGKAPPL_01480	7.87e-289	-	-	-	-	-	-	-	-
DHGKAPPL_01481	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
DHGKAPPL_01482	7.79e-78	-	-	-	-	-	-	-	-
DHGKAPPL_01483	2.79e-181	-	-	-	-	-	-	-	-
DHGKAPPL_01484	2.14e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHGKAPPL_01485	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
DHGKAPPL_01486	6.02e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
DHGKAPPL_01487	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
DHGKAPPL_01489	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_01490	2.82e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
DHGKAPPL_01491	2.37e-65	-	-	-	-	-	-	-	-
DHGKAPPL_01492	3.03e-40	-	-	-	-	-	-	-	-
DHGKAPPL_01493	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DHGKAPPL_01494	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
DHGKAPPL_01495	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
DHGKAPPL_01496	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01497	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DHGKAPPL_01498	2.42e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01499	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
DHGKAPPL_01501	2.31e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
DHGKAPPL_01502	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
DHGKAPPL_01503	7.51e-166	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
DHGKAPPL_01505	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
DHGKAPPL_01506	4.75e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
DHGKAPPL_01507	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DHGKAPPL_01508	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHGKAPPL_01509	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DHGKAPPL_01510	1.1e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DHGKAPPL_01511	1.96e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHGKAPPL_01512	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DHGKAPPL_01513	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DHGKAPPL_01514	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
DHGKAPPL_01515	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DHGKAPPL_01516	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
DHGKAPPL_01517	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
DHGKAPPL_01518	6.79e-249	-	-	-	-	-	-	-	-
DHGKAPPL_01519	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DHGKAPPL_01520	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DHGKAPPL_01521	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_01522	1.58e-85	-	-	-	V	-	-	-	LD-carboxypeptidase
DHGKAPPL_01523	3.4e-134	-	-	-	V	-	-	-	LD-carboxypeptidase
DHGKAPPL_01524	5.01e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
DHGKAPPL_01525	1.64e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_01526	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
DHGKAPPL_01527	1.59e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
DHGKAPPL_01528	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
DHGKAPPL_01529	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
DHGKAPPL_01530	3.1e-229	-	-	-	P	-	-	-	Major Facilitator Superfamily
DHGKAPPL_01531	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_01532	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DHGKAPPL_01534	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DHGKAPPL_01535	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DHGKAPPL_01536	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DHGKAPPL_01537	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DHGKAPPL_01538	8.37e-231	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DHGKAPPL_01539	4.86e-235	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DHGKAPPL_01540	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_01541	1.31e-109	-	-	-	T	-	-	-	Universal stress protein family
DHGKAPPL_01542	5.51e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DHGKAPPL_01543	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01544	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHGKAPPL_01546	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
DHGKAPPL_01547	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DHGKAPPL_01548	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
DHGKAPPL_01549	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
DHGKAPPL_01550	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DHGKAPPL_01551	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
DHGKAPPL_01552	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DHGKAPPL_01553	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DHGKAPPL_01554	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DHGKAPPL_01555	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DHGKAPPL_01556	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DHGKAPPL_01557	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DHGKAPPL_01558	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DHGKAPPL_01559	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DHGKAPPL_01560	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DHGKAPPL_01561	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DHGKAPPL_01562	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DHGKAPPL_01563	1.44e-55	-	-	-	-	-	-	-	-
DHGKAPPL_01564	1.52e-67	-	-	-	-	-	-	-	-
DHGKAPPL_01565	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
DHGKAPPL_01566	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
DHGKAPPL_01567	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DHGKAPPL_01568	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DHGKAPPL_01569	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHGKAPPL_01570	1.06e-53	-	-	-	-	-	-	-	-
DHGKAPPL_01571	4e-40	-	-	-	S	-	-	-	CsbD-like
DHGKAPPL_01572	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
DHGKAPPL_01573	5.79e-21	-	-	-	-	-	-	-	-
DHGKAPPL_01574	1.51e-48	-	-	-	-	-	-	-	-
DHGKAPPL_01575	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DHGKAPPL_01576	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
DHGKAPPL_01577	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHGKAPPL_01578	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
DHGKAPPL_01579	2.05e-55	-	-	-	-	-	-	-	-
DHGKAPPL_01580	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DHGKAPPL_01581	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
DHGKAPPL_01582	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DHGKAPPL_01583	1.42e-39	-	-	-	-	-	-	-	-
DHGKAPPL_01584	2.1e-71	-	-	-	-	-	-	-	-
DHGKAPPL_01586	1.19e-13	-	-	-	-	-	-	-	-
DHGKAPPL_01590	8.14e-47	-	-	-	L	-	-	-	Pfam:Integrase_AP2
DHGKAPPL_01591	1.24e-36	yafC	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_01592	4.15e-130	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
DHGKAPPL_01594	2.74e-05	-	-	-	-	-	-	-	-
DHGKAPPL_01595	5.67e-25	-	-	-	S	-	-	-	Bacteriophage holin
DHGKAPPL_01596	5.7e-35	-	-	-	S	-	-	-	Haemolysin XhlA
DHGKAPPL_01597	7.88e-160	-	-	-	M	-	-	-	hydrolase, family 25
DHGKAPPL_01598	1.05e-33	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
DHGKAPPL_01601	1.58e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
DHGKAPPL_01602	3.46e-241	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHGKAPPL_01603	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
DHGKAPPL_01604	9.8e-182	-	-	-	S	-	-	-	phage tail
DHGKAPPL_01605	0.0	-	-	-	D	-	-	-	domain protein
DHGKAPPL_01606	8.92e-112	-	-	-	D	-	-	-	domain protein
DHGKAPPL_01608	1.41e-115	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
DHGKAPPL_01609	5.14e-137	-	-	-	-	-	-	-	-
DHGKAPPL_01610	1.9e-86	-	-	-	-	-	-	-	-
DHGKAPPL_01611	1.21e-116	-	-	-	-	-	-	-	-
DHGKAPPL_01612	8.45e-62	-	-	-	-	-	-	-	-
DHGKAPPL_01613	2.36e-70	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DHGKAPPL_01614	2.44e-245	gpG	-	-	-	-	-	-	-
DHGKAPPL_01615	9.86e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
DHGKAPPL_01616	1.87e-221	-	-	-	S	-	-	-	Phage Mu protein F like protein
DHGKAPPL_01617	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DHGKAPPL_01618	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
DHGKAPPL_01619	7.13e-42	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
DHGKAPPL_01622	1.03e-74	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
DHGKAPPL_01623	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHGKAPPL_01624	1.49e-50	-	-	-	-	-	-	-	-
DHGKAPPL_01626	1.99e-199	-	-	-	S	-	-	-	IstB-like ATP binding protein
DHGKAPPL_01627	2.75e-41	-	-	-	L	-	-	-	DnaD domain protein
DHGKAPPL_01628	8.54e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
DHGKAPPL_01629	1.12e-121	-	-	-	S	-	-	-	AAA domain
DHGKAPPL_01630	3.3e-46	-	-	-	-	-	-	-	-
DHGKAPPL_01638	4.61e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DHGKAPPL_01639	5.68e-40	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DHGKAPPL_01642	2.06e-51	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
DHGKAPPL_01645	1.44e-31	-	-	-	-	-	-	-	-
DHGKAPPL_01649	6.02e-196	-	-	-	L	-	-	-	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DHGKAPPL_01650	4.19e-159	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
DHGKAPPL_01651	5.09e-104	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DHGKAPPL_01652	1.88e-192	-	-	-	O	-	-	-	Band 7 protein
DHGKAPPL_01653	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_01654	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
DHGKAPPL_01655	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DHGKAPPL_01656	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
DHGKAPPL_01657	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_01658	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DHGKAPPL_01659	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
DHGKAPPL_01660	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
DHGKAPPL_01661	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DHGKAPPL_01662	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DHGKAPPL_01663	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DHGKAPPL_01664	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
DHGKAPPL_01665	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DHGKAPPL_01666	3.11e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DHGKAPPL_01667	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DHGKAPPL_01668	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DHGKAPPL_01669	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DHGKAPPL_01670	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DHGKAPPL_01671	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DHGKAPPL_01672	4.64e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01673	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_01674	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
DHGKAPPL_01675	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHGKAPPL_01676	1.38e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
DHGKAPPL_01677	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
DHGKAPPL_01678	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DHGKAPPL_01679	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
DHGKAPPL_01680	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
DHGKAPPL_01681	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DHGKAPPL_01682	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DHGKAPPL_01683	6.14e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
DHGKAPPL_01684	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
DHGKAPPL_01685	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DHGKAPPL_01686	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
DHGKAPPL_01687	9.13e-21	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
DHGKAPPL_01688	3.58e-306	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
DHGKAPPL_01690	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DHGKAPPL_01691	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DHGKAPPL_01692	1.1e-112	-	-	-	-	-	-	-	-
DHGKAPPL_01693	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DHGKAPPL_01694	1.03e-66	-	-	-	-	-	-	-	-
DHGKAPPL_01695	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DHGKAPPL_01696	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DHGKAPPL_01697	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DHGKAPPL_01698	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DHGKAPPL_01699	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DHGKAPPL_01700	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DHGKAPPL_01701	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DHGKAPPL_01702	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DHGKAPPL_01703	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DHGKAPPL_01704	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DHGKAPPL_01705	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DHGKAPPL_01706	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DHGKAPPL_01707	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DHGKAPPL_01708	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DHGKAPPL_01709	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DHGKAPPL_01710	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DHGKAPPL_01711	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DHGKAPPL_01712	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DHGKAPPL_01713	9.9e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DHGKAPPL_01714	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DHGKAPPL_01715	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DHGKAPPL_01716	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DHGKAPPL_01717	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DHGKAPPL_01718	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DHGKAPPL_01719	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DHGKAPPL_01720	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DHGKAPPL_01721	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DHGKAPPL_01722	2.38e-72	-	-	-	-	-	-	-	-
DHGKAPPL_01723	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_01724	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DHGKAPPL_01725	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01726	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01727	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DHGKAPPL_01728	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DHGKAPPL_01729	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DHGKAPPL_01730	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DHGKAPPL_01731	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHGKAPPL_01732	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHGKAPPL_01733	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DHGKAPPL_01734	5.46e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DHGKAPPL_01735	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DHGKAPPL_01736	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DHGKAPPL_01737	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DHGKAPPL_01738	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DHGKAPPL_01739	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DHGKAPPL_01740	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DHGKAPPL_01741	6.69e-124	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_01742	9.81e-27	-	-	-	-	-	-	-	-
DHGKAPPL_01746	2.97e-41	-	-	-	-	-	-	-	-
DHGKAPPL_01747	5.37e-74	-	-	-	-	-	-	-	-
DHGKAPPL_01748	4.14e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
DHGKAPPL_01749	1.34e-232	-	-	-	-	-	-	-	-
DHGKAPPL_01750	1.77e-205	-	-	-	-	-	-	-	-
DHGKAPPL_01751	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DHGKAPPL_01752	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
DHGKAPPL_01753	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DHGKAPPL_01754	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DHGKAPPL_01755	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DHGKAPPL_01756	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DHGKAPPL_01757	6.61e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
DHGKAPPL_01758	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DHGKAPPL_01759	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DHGKAPPL_01760	2.47e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DHGKAPPL_01761	5.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DHGKAPPL_01762	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DHGKAPPL_01763	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DHGKAPPL_01764	0.0	-	-	-	S	-	-	-	membrane
DHGKAPPL_01765	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DHGKAPPL_01766	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
DHGKAPPL_01767	9.72e-146	-	-	-	S	-	-	-	membrane
DHGKAPPL_01768	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHGKAPPL_01769	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DHGKAPPL_01770	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DHGKAPPL_01771	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHGKAPPL_01772	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DHGKAPPL_01773	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DHGKAPPL_01774	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHGKAPPL_01775	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHGKAPPL_01776	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DHGKAPPL_01777	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHGKAPPL_01778	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
DHGKAPPL_01779	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DHGKAPPL_01780	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DHGKAPPL_01781	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DHGKAPPL_01782	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHGKAPPL_01783	1.38e-155	csrR	-	-	K	-	-	-	response regulator
DHGKAPPL_01784	8.27e-248	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DHGKAPPL_01785	3.2e-27	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DHGKAPPL_01786	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DHGKAPPL_01787	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHGKAPPL_01788	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DHGKAPPL_01789	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DHGKAPPL_01790	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DHGKAPPL_01791	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
DHGKAPPL_01792	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DHGKAPPL_01793	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DHGKAPPL_01794	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DHGKAPPL_01795	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DHGKAPPL_01796	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DHGKAPPL_01797	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DHGKAPPL_01798	1.81e-113	-	-	-	-	-	-	-	-
DHGKAPPL_01799	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
DHGKAPPL_01800	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DHGKAPPL_01801	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DHGKAPPL_01802	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DHGKAPPL_01803	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
DHGKAPPL_01804	2.76e-74	-	-	-	-	-	-	-	-
DHGKAPPL_01805	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DHGKAPPL_01806	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DHGKAPPL_01807	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DHGKAPPL_01808	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DHGKAPPL_01809	4.97e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DHGKAPPL_01810	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DHGKAPPL_01811	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DHGKAPPL_01812	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DHGKAPPL_01813	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DHGKAPPL_01814	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DHGKAPPL_01815	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DHGKAPPL_01816	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DHGKAPPL_01817	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DHGKAPPL_01818	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DHGKAPPL_01819	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DHGKAPPL_01820	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DHGKAPPL_01821	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DHGKAPPL_01822	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DHGKAPPL_01823	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
DHGKAPPL_01824	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DHGKAPPL_01825	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
DHGKAPPL_01826	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DHGKAPPL_01827	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DHGKAPPL_01828	1.69e-144	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHGKAPPL_01829	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DHGKAPPL_01830	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DHGKAPPL_01831	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
DHGKAPPL_01832	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_01833	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_01834	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DHGKAPPL_01835	7.9e-72	-	-	-	-	-	-	-	-
DHGKAPPL_01836	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DHGKAPPL_01837	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_01838	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
DHGKAPPL_01839	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
DHGKAPPL_01840	4.75e-80	-	-	-	-	-	-	-	-
DHGKAPPL_01841	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_01842	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DHGKAPPL_01843	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_01844	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DHGKAPPL_01845	3.39e-138	-	-	-	-	-	-	-	-
DHGKAPPL_01846	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
DHGKAPPL_01847	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DHGKAPPL_01848	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DHGKAPPL_01849	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
DHGKAPPL_01850	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DHGKAPPL_01851	0.0	-	-	-	S	-	-	-	membrane
DHGKAPPL_01852	2.24e-87	-	-	-	S	-	-	-	NUDIX domain
DHGKAPPL_01853	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHGKAPPL_01854	1.44e-231	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DHGKAPPL_01855	0.0	-	-	-	L	-	-	-	MutS domain V
DHGKAPPL_01856	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
DHGKAPPL_01857	4.09e-253	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHGKAPPL_01858	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DHGKAPPL_01859	1.4e-189	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DHGKAPPL_01860	7.13e-59	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DHGKAPPL_01862	3.33e-27	-	-	-	M	-	-	-	domain protein
DHGKAPPL_01863	4.04e-62	-	-	-	M	-	-	-	domain protein
DHGKAPPL_01864	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
DHGKAPPL_01865	7.43e-28	-	-	-	M	-	-	-	domain protein
DHGKAPPL_01866	2.68e-71	-	-	-	M	-	-	-	domain protein
DHGKAPPL_01867	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
DHGKAPPL_01868	4.43e-129	-	-	-	-	-	-	-	-
DHGKAPPL_01869	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHGKAPPL_01870	2.33e-142	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHGKAPPL_01871	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_01872	9.81e-233	-	-	-	M	-	-	-	Peptidase family S41
DHGKAPPL_01873	2.24e-277	-	-	-	-	-	-	-	-
DHGKAPPL_01874	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHGKAPPL_01875	0.0	yhaN	-	-	L	-	-	-	AAA domain
DHGKAPPL_01876	5e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
DHGKAPPL_01877	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DHGKAPPL_01878	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DHGKAPPL_01879	2.43e-18	-	-	-	-	-	-	-	-
DHGKAPPL_01880	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DHGKAPPL_01881	9.65e-272	arcT	-	-	E	-	-	-	Aminotransferase
DHGKAPPL_01882	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
DHGKAPPL_01883	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
DHGKAPPL_01884	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGKAPPL_01885	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DHGKAPPL_01886	1.1e-70	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
DHGKAPPL_01887	1.14e-191	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
DHGKAPPL_01888	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_01889	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_01890	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_01891	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DHGKAPPL_01892	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DHGKAPPL_01893	0.0	celR	-	-	K	-	-	-	PRD domain
DHGKAPPL_01894	6.25e-138	-	-	-	-	-	-	-	-
DHGKAPPL_01895	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DHGKAPPL_01896	3.81e-105	-	-	-	-	-	-	-	-
DHGKAPPL_01897	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DHGKAPPL_01898	7.02e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
DHGKAPPL_01901	1.79e-42	-	-	-	-	-	-	-	-
DHGKAPPL_01902	2.69e-316	dinF	-	-	V	-	-	-	MatE
DHGKAPPL_01903	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
DHGKAPPL_01904	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
DHGKAPPL_01905	5.68e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
DHGKAPPL_01906	2.24e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
DHGKAPPL_01907	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
DHGKAPPL_01908	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
DHGKAPPL_01909	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DHGKAPPL_01910	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DHGKAPPL_01911	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
DHGKAPPL_01912	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
DHGKAPPL_01913	3.89e-237	-	-	-	-	-	-	-	-
DHGKAPPL_01914	9.03e-16	-	-	-	-	-	-	-	-
DHGKAPPL_01915	4.29e-87	-	-	-	-	-	-	-	-
DHGKAPPL_01918	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
DHGKAPPL_01919	7.12e-62	-	-	-	-	-	-	-	-
DHGKAPPL_01920	8.82e-119	-	-	-	-	-	-	-	-
DHGKAPPL_01921	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_01922	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_01923	4.56e-78	-	-	-	-	-	-	-	-
DHGKAPPL_01924	5.37e-74	-	-	-	-	-	-	-	-
DHGKAPPL_01925	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DHGKAPPL_01926	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DHGKAPPL_01927	7.83e-140	-	-	-	-	-	-	-	-
DHGKAPPL_01928	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_01929	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DHGKAPPL_01930	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
DHGKAPPL_01931	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_01932	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHGKAPPL_01933	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
DHGKAPPL_01934	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_01935	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
DHGKAPPL_01937	7.61e-316	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
DHGKAPPL_01938	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DHGKAPPL_01939	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DHGKAPPL_01940	1.56e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
DHGKAPPL_01941	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DHGKAPPL_01942	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_01943	4.59e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_01944	4.15e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
DHGKAPPL_01945	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHGKAPPL_01946	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DHGKAPPL_01947	1.83e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DHGKAPPL_01948	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DHGKAPPL_01949	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DHGKAPPL_01950	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DHGKAPPL_01951	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DHGKAPPL_01952	3.54e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
DHGKAPPL_01953	9.32e-40	-	-	-	-	-	-	-	-
DHGKAPPL_01954	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHGKAPPL_01955	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHGKAPPL_01956	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
DHGKAPPL_01957	3.85e-300	-	-	-	N	-	-	-	Cell shape-determining protein MreB
DHGKAPPL_01958	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_01959	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DHGKAPPL_01960	5.79e-158	-	-	-	-	-	-	-	-
DHGKAPPL_01961	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHGKAPPL_01962	3.91e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
DHGKAPPL_01963	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
DHGKAPPL_01964	2.08e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
DHGKAPPL_01965	6.57e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DHGKAPPL_01967	1.7e-199	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DHGKAPPL_01968	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_01969	2.07e-123	-	-	-	-	-	-	-	-
DHGKAPPL_01970	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
DHGKAPPL_01971	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
DHGKAPPL_01983	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DHGKAPPL_01986	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DHGKAPPL_01987	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DHGKAPPL_01988	1.22e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHGKAPPL_01989	1.09e-290	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DHGKAPPL_01990	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DHGKAPPL_01991	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DHGKAPPL_01992	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DHGKAPPL_01993	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DHGKAPPL_01994	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DHGKAPPL_01995	5.6e-41	-	-	-	-	-	-	-	-
DHGKAPPL_01996	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DHGKAPPL_01997	2.5e-132	-	-	-	L	-	-	-	Integrase
DHGKAPPL_01998	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DHGKAPPL_01999	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DHGKAPPL_02000	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DHGKAPPL_02001	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGKAPPL_02002	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGKAPPL_02003	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_02004	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
DHGKAPPL_02005	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DHGKAPPL_02006	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_02007	1.49e-252	-	-	-	M	-	-	-	MucBP domain
DHGKAPPL_02008	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_02009	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DHGKAPPL_02010	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DHGKAPPL_02011	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
DHGKAPPL_02012	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DHGKAPPL_02013	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DHGKAPPL_02014	2.46e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
DHGKAPPL_02015	3.25e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
DHGKAPPL_02016	2.97e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHGKAPPL_02017	4.35e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
DHGKAPPL_02018	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
DHGKAPPL_02019	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
DHGKAPPL_02020	3.53e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
DHGKAPPL_02021	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
DHGKAPPL_02022	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DHGKAPPL_02023	1.9e-168	-	-	-	-	-	-	-	-
DHGKAPPL_02024	4.14e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DHGKAPPL_02025	1.64e-35	-	-	-	-	-	-	-	-
DHGKAPPL_02026	1.95e-41	-	-	-	-	-	-	-	-
DHGKAPPL_02027	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DHGKAPPL_02028	1.06e-68	-	-	-	-	-	-	-	-
DHGKAPPL_02029	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
DHGKAPPL_02030	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DHGKAPPL_02031	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_02032	0.0	-	-	-	M	-	-	-	domain protein
DHGKAPPL_02033	3.97e-174	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DHGKAPPL_02034	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DHGKAPPL_02035	3.82e-255	cps3I	-	-	G	-	-	-	Acyltransferase family
DHGKAPPL_02036	7.45e-258	cps3H	-	-	-	-	-	-	-
DHGKAPPL_02037	2.88e-208	cps3F	-	-	-	-	-	-	-
DHGKAPPL_02038	6.87e-144	cps3E	-	-	-	-	-	-	-
DHGKAPPL_02039	3.93e-260	cps3D	-	-	-	-	-	-	-
DHGKAPPL_02040	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DHGKAPPL_02041	4.65e-229	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DHGKAPPL_02042	1.41e-169	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DHGKAPPL_02043	1.37e-26	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
DHGKAPPL_02044	8.7e-116	-	-	-	S	-	-	-	Acyltransferase family
DHGKAPPL_02045	2.27e-304	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHGKAPPL_02046	1.72e-166	cps2G	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
DHGKAPPL_02047	9.38e-161	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
DHGKAPPL_02049	1.62e-191	-	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
DHGKAPPL_02050	6.41e-59	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DHGKAPPL_02051	5.9e-160	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
DHGKAPPL_02052	5.19e-224	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DHGKAPPL_02053	1.49e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DHGKAPPL_02054	1.43e-164	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DHGKAPPL_02055	1.94e-169	epsB	-	-	M	-	-	-	biosynthesis protein
DHGKAPPL_02056	5.1e-134	-	-	-	L	-	-	-	Integrase
DHGKAPPL_02057	4.36e-203	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DHGKAPPL_02058	1.39e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DHGKAPPL_02059	5.58e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DHGKAPPL_02060	6.5e-189	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DHGKAPPL_02061	5.98e-181	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHGKAPPL_02063	2.87e-14	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
DHGKAPPL_02066	8.64e-41	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DHGKAPPL_02067	1.57e-50	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
DHGKAPPL_02069	1.56e-75	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
DHGKAPPL_02070	5.64e-57	-	-	GT2,GT4	M	ko:K07011,ko:K20444	-	ko00000,ko01000,ko01005,ko02000	PFAM Glycosyl transferase family 2
DHGKAPPL_02071	8.4e-125	-	-	-	M	-	-	-	Parallel beta-helix repeats
DHGKAPPL_02072	4.34e-109	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DHGKAPPL_02073	9.45e-75	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
DHGKAPPL_02074	5.99e-102	-	-	-	G	-	-	-	Glycosyltransferase Family 4
DHGKAPPL_02075	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_02076	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DHGKAPPL_02077	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DHGKAPPL_02078	1.63e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
DHGKAPPL_02079	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
DHGKAPPL_02080	2.9e-139	-	-	-	-	-	-	-	-
DHGKAPPL_02081	7.62e-97	-	-	-	-	-	-	-	-
DHGKAPPL_02083	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_02084	5.73e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02085	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
DHGKAPPL_02087	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DHGKAPPL_02088	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
DHGKAPPL_02089	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DHGKAPPL_02090	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DHGKAPPL_02091	7.76e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DHGKAPPL_02092	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
DHGKAPPL_02093	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_02094	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02095	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DHGKAPPL_02096	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_02097	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHGKAPPL_02098	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DHGKAPPL_02099	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHGKAPPL_02100	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DHGKAPPL_02101	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHGKAPPL_02102	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
DHGKAPPL_02103	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DHGKAPPL_02104	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DHGKAPPL_02105	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DHGKAPPL_02106	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
DHGKAPPL_02107	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DHGKAPPL_02108	9.78e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DHGKAPPL_02109	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DHGKAPPL_02110	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DHGKAPPL_02111	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DHGKAPPL_02112	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DHGKAPPL_02113	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DHGKAPPL_02114	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DHGKAPPL_02115	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DHGKAPPL_02116	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DHGKAPPL_02117	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
DHGKAPPL_02118	2.56e-34	-	-	-	-	-	-	-	-
DHGKAPPL_02119	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DHGKAPPL_02120	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DHGKAPPL_02121	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
DHGKAPPL_02122	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DHGKAPPL_02123	6.5e-215	mleR	-	-	K	-	-	-	LysR family
DHGKAPPL_02124	2.62e-206	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
DHGKAPPL_02125	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DHGKAPPL_02126	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHGKAPPL_02127	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DHGKAPPL_02128	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DHGKAPPL_02129	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DHGKAPPL_02130	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DHGKAPPL_02131	3.35e-233	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DHGKAPPL_02132	3.88e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DHGKAPPL_02133	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
DHGKAPPL_02134	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DHGKAPPL_02135	3.75e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DHGKAPPL_02136	1.18e-66	-	-	-	-	-	-	-	-
DHGKAPPL_02137	1.22e-221	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DHGKAPPL_02138	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DHGKAPPL_02139	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DHGKAPPL_02140	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DHGKAPPL_02141	1.55e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_02142	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
DHGKAPPL_02143	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
DHGKAPPL_02144	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DHGKAPPL_02145	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DHGKAPPL_02146	3.51e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DHGKAPPL_02147	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
DHGKAPPL_02148	1.65e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DHGKAPPL_02149	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHGKAPPL_02150	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DHGKAPPL_02151	5.79e-234	-	-	-	S	-	-	-	Membrane
DHGKAPPL_02152	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DHGKAPPL_02153	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DHGKAPPL_02154	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DHGKAPPL_02155	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DHGKAPPL_02156	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGKAPPL_02157	3.47e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGKAPPL_02158	3.42e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGKAPPL_02159	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DHGKAPPL_02160	3.19e-194	-	-	-	S	-	-	-	FMN_bind
DHGKAPPL_02161	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DHGKAPPL_02162	5.37e-112	-	-	-	S	-	-	-	NusG domain II
DHGKAPPL_02163	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
DHGKAPPL_02164	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DHGKAPPL_02165	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DHGKAPPL_02166	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHGKAPPL_02167	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DHGKAPPL_02168	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DHGKAPPL_02169	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DHGKAPPL_02170	5.28e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DHGKAPPL_02171	1.99e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DHGKAPPL_02172	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DHGKAPPL_02173	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DHGKAPPL_02174	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DHGKAPPL_02175	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DHGKAPPL_02176	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DHGKAPPL_02177	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DHGKAPPL_02178	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DHGKAPPL_02179	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DHGKAPPL_02180	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DHGKAPPL_02181	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DHGKAPPL_02182	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DHGKAPPL_02183	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DHGKAPPL_02184	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DHGKAPPL_02185	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DHGKAPPL_02186	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DHGKAPPL_02187	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DHGKAPPL_02188	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DHGKAPPL_02189	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DHGKAPPL_02190	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DHGKAPPL_02191	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DHGKAPPL_02192	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DHGKAPPL_02193	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DHGKAPPL_02194	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DHGKAPPL_02195	1e-147	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
DHGKAPPL_02196	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHGKAPPL_02197	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHGKAPPL_02198	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_02199	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DHGKAPPL_02200	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DHGKAPPL_02208	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DHGKAPPL_02209	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DHGKAPPL_02210	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
DHGKAPPL_02211	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DHGKAPPL_02212	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_02213	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02214	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DHGKAPPL_02215	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHGKAPPL_02216	2.05e-153	-	-	-	I	-	-	-	phosphatase
DHGKAPPL_02217	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DHGKAPPL_02218	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DHGKAPPL_02219	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
DHGKAPPL_02220	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DHGKAPPL_02221	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DHGKAPPL_02222	1.36e-77	-	-	-	-	-	-	-	-
DHGKAPPL_02223	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DHGKAPPL_02224	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHGKAPPL_02225	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DHGKAPPL_02226	1.46e-170	-	-	-	-	-	-	-	-
DHGKAPPL_02227	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DHGKAPPL_02228	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
DHGKAPPL_02229	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
DHGKAPPL_02230	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DHGKAPPL_02231	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
DHGKAPPL_02232	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHGKAPPL_02233	0.0	xylP2	-	-	G	-	-	-	symporter
DHGKAPPL_02234	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHGKAPPL_02235	3.33e-64	-	-	-	-	-	-	-	-
DHGKAPPL_02236	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
DHGKAPPL_02237	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
DHGKAPPL_02238	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DHGKAPPL_02239	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DHGKAPPL_02240	1.12e-243	-	-	-	-	-	-	-	-
DHGKAPPL_02241	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHGKAPPL_02242	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_02243	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHGKAPPL_02244	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DHGKAPPL_02245	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
DHGKAPPL_02246	5.44e-56	-	-	-	-	-	-	-	-
DHGKAPPL_02247	3.79e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DHGKAPPL_02248	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHGKAPPL_02249	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DHGKAPPL_02250	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DHGKAPPL_02251	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DHGKAPPL_02252	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02254	0.0	-	-	-	C	-	-	-	FMN_bind
DHGKAPPL_02255	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02256	1.88e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_02257	1.06e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
DHGKAPPL_02258	2.87e-112	-	-	-	S	-	-	-	AAA domain
DHGKAPPL_02259	1.42e-08	-	-	-	-	-	-	-	-
DHGKAPPL_02260	0.0	-	-	-	M	-	-	-	MucBP domain
DHGKAPPL_02261	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
DHGKAPPL_02262	3.37e-60	-	-	-	S	-	-	-	MazG-like family
DHGKAPPL_02263	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DHGKAPPL_02264	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DHGKAPPL_02265	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
DHGKAPPL_02266	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DHGKAPPL_02267	1.73e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DHGKAPPL_02268	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
DHGKAPPL_02269	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DHGKAPPL_02270	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DHGKAPPL_02271	5.74e-32	-	-	-	-	-	-	-	-
DHGKAPPL_02272	1.95e-116	-	-	-	-	-	-	-	-
DHGKAPPL_02273	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
DHGKAPPL_02274	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
DHGKAPPL_02275	3.61e-61	-	-	-	S	-	-	-	MORN repeat
DHGKAPPL_02276	3.5e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
DHGKAPPL_02277	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
DHGKAPPL_02278	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DHGKAPPL_02279	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02280	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_02281	1.08e-71	-	-	-	-	-	-	-	-
DHGKAPPL_02282	8.81e-66	-	-	-	-	-	-	-	-
DHGKAPPL_02283	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHGKAPPL_02284	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHGKAPPL_02285	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHGKAPPL_02286	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
DHGKAPPL_02288	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
DHGKAPPL_02290	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DHGKAPPL_02291	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DHGKAPPL_02292	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DHGKAPPL_02293	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DHGKAPPL_02294	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DHGKAPPL_02295	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
DHGKAPPL_02296	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DHGKAPPL_02297	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
DHGKAPPL_02298	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
DHGKAPPL_02299	1.61e-36	-	-	-	-	-	-	-	-
DHGKAPPL_02300	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
DHGKAPPL_02301	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
DHGKAPPL_02302	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DHGKAPPL_02303	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_02304	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DHGKAPPL_02305	6.5e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHGKAPPL_02306	3.08e-93	-	-	-	K	-	-	-	MarR family
DHGKAPPL_02307	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
DHGKAPPL_02308	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_02309	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DHGKAPPL_02310	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
DHGKAPPL_02311	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DHGKAPPL_02312	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DHGKAPPL_02313	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DHGKAPPL_02314	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02315	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02316	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DHGKAPPL_02317	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_02319	1.28e-54	-	-	-	-	-	-	-	-
DHGKAPPL_02320	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGKAPPL_02321	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHGKAPPL_02322	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
DHGKAPPL_02323	1.01e-188	-	-	-	-	-	-	-	-
DHGKAPPL_02324	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DHGKAPPL_02325	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DHGKAPPL_02326	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DHGKAPPL_02327	1.48e-27	-	-	-	-	-	-	-	-
DHGKAPPL_02328	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
DHGKAPPL_02329	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DHGKAPPL_02330	6.12e-115	-	-	-	-	-	-	-	-
DHGKAPPL_02331	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DHGKAPPL_02332	1.09e-60	-	-	-	-	-	-	-	-
DHGKAPPL_02333	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
DHGKAPPL_02334	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DHGKAPPL_02335	0.0	oatA	-	-	I	-	-	-	Acyltransferase
DHGKAPPL_02336	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DHGKAPPL_02337	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DHGKAPPL_02338	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_02339	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DHGKAPPL_02340	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DHGKAPPL_02341	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DHGKAPPL_02342	1.36e-27	-	-	-	-	-	-	-	-
DHGKAPPL_02343	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02344	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
DHGKAPPL_02345	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHGKAPPL_02346	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DHGKAPPL_02347	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHGKAPPL_02348	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_02349	2.08e-117	-	-	-	V	-	-	-	VanZ like family
DHGKAPPL_02350	3.88e-46	-	-	-	-	-	-	-	-
DHGKAPPL_02351	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
DHGKAPPL_02353	4.13e-182	-	-	-	-	-	-	-	-
DHGKAPPL_02354	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DHGKAPPL_02355	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DHGKAPPL_02356	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
DHGKAPPL_02357	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DHGKAPPL_02358	2.49e-95	-	-	-	-	-	-	-	-
DHGKAPPL_02359	3.38e-70	-	-	-	-	-	-	-	-
DHGKAPPL_02360	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DHGKAPPL_02361	7.01e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_02362	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_02363	3.15e-158	-	-	-	T	-	-	-	EAL domain
DHGKAPPL_02364	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DHGKAPPL_02365	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DHGKAPPL_02366	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
DHGKAPPL_02367	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DHGKAPPL_02368	2.7e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
DHGKAPPL_02369	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHGKAPPL_02370	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHGKAPPL_02371	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DHGKAPPL_02372	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
DHGKAPPL_02373	1.46e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DHGKAPPL_02374	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DHGKAPPL_02375	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DHGKAPPL_02376	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DHGKAPPL_02377	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DHGKAPPL_02378	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DHGKAPPL_02379	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_02380	7.98e-137	-	-	-	-	-	-	-	-
DHGKAPPL_02381	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_02382	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_02383	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
DHGKAPPL_02384	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DHGKAPPL_02385	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DHGKAPPL_02386	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
DHGKAPPL_02387	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DHGKAPPL_02388	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DHGKAPPL_02389	5.11e-171	-	-	-	-	-	-	-	-
DHGKAPPL_02390	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHGKAPPL_02391	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DHGKAPPL_02392	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DHGKAPPL_02393	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DHGKAPPL_02394	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
DHGKAPPL_02395	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
DHGKAPPL_02397	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DHGKAPPL_02398	8.95e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGKAPPL_02399	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_02400	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DHGKAPPL_02401	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DHGKAPPL_02402	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DHGKAPPL_02403	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DHGKAPPL_02404	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DHGKAPPL_02405	4.34e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DHGKAPPL_02406	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DHGKAPPL_02407	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DHGKAPPL_02408	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DHGKAPPL_02409	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DHGKAPPL_02410	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
DHGKAPPL_02411	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DHGKAPPL_02412	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DHGKAPPL_02413	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DHGKAPPL_02414	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DHGKAPPL_02415	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DHGKAPPL_02416	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
DHGKAPPL_02417	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DHGKAPPL_02418	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
DHGKAPPL_02419	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
DHGKAPPL_02420	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
DHGKAPPL_02421	6.83e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
DHGKAPPL_02422	4.95e-310	-	-	-	-	-	-	-	-
DHGKAPPL_02423	1.06e-205	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DHGKAPPL_02424	0.0	nox	-	-	C	-	-	-	NADH oxidase
DHGKAPPL_02425	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
DHGKAPPL_02426	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DHGKAPPL_02427	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DHGKAPPL_02428	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DHGKAPPL_02429	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DHGKAPPL_02430	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DHGKAPPL_02431	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
DHGKAPPL_02432	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DHGKAPPL_02433	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHGKAPPL_02434	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHGKAPPL_02435	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DHGKAPPL_02436	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DHGKAPPL_02437	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DHGKAPPL_02438	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHGKAPPL_02439	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DHGKAPPL_02440	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DHGKAPPL_02441	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DHGKAPPL_02442	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DHGKAPPL_02443	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DHGKAPPL_02444	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DHGKAPPL_02445	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DHGKAPPL_02446	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DHGKAPPL_02447	7.67e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DHGKAPPL_02448	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
DHGKAPPL_02449	0.0	ydaO	-	-	E	-	-	-	amino acid
DHGKAPPL_02450	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DHGKAPPL_02451	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DHGKAPPL_02452	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02453	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DHGKAPPL_02454	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DHGKAPPL_02455	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DHGKAPPL_02456	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DHGKAPPL_02457	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DHGKAPPL_02458	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DHGKAPPL_02459	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DHGKAPPL_02460	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DHGKAPPL_02461	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
DHGKAPPL_02462	4.73e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02463	1.14e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
DHGKAPPL_02464	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
DHGKAPPL_02465	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DHGKAPPL_02466	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DHGKAPPL_02467	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DHGKAPPL_02468	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DHGKAPPL_02469	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DHGKAPPL_02470	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DHGKAPPL_02471	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DHGKAPPL_02472	1.16e-128	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
DHGKAPPL_02473	4.67e-280	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DHGKAPPL_02474	2.27e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_02475	4.97e-67	-	2.7.1.194	-	G	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_02476	7.75e-297	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DHGKAPPL_02477	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DHGKAPPL_02478	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DHGKAPPL_02479	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DHGKAPPL_02480	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHGKAPPL_02481	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DHGKAPPL_02482	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
DHGKAPPL_02483	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DHGKAPPL_02484	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHGKAPPL_02485	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHGKAPPL_02486	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DHGKAPPL_02487	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DHGKAPPL_02488	1.78e-88	-	-	-	L	-	-	-	nuclease
DHGKAPPL_02489	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DHGKAPPL_02490	1.85e-55	-	-	-	S	-	-	-	Bacteriophage holin
DHGKAPPL_02491	4.55e-64	-	-	-	-	-	-	-	-
DHGKAPPL_02492	2.33e-260	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DHGKAPPL_02494	1.22e-61	-	-	-	-	-	-	-	-
DHGKAPPL_02498	2.18e-86	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DHGKAPPL_02501	2.01e-123	-	-	-	S	-	-	-	Prophage endopeptidase tail
DHGKAPPL_02503	9.77e-180	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DHGKAPPL_02506	1.5e-56	-	-	-	N	-	-	-	domain, Protein
DHGKAPPL_02511	5.98e-06	-	-	-	-	-	-	-	-
DHGKAPPL_02512	1.73e-135	-	-	-	-	-	-	-	-
DHGKAPPL_02515	1.07e-53	-	-	-	S	-	-	-	Phage minor capsid protein 2
DHGKAPPL_02516	1.89e-137	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DHGKAPPL_02517	4.91e-235	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
DHGKAPPL_02518	3.18e-61	-	-	-	L	-	-	-	transposase activity
DHGKAPPL_02519	2.79e-35	-	-	-	-	-	-	-	-
DHGKAPPL_02520	2.32e-22	-	-	-	-	-	-	-	-
DHGKAPPL_02521	2.19e-16	-	-	-	-	-	-	-	-
DHGKAPPL_02527	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
DHGKAPPL_02530	5.21e-119	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
DHGKAPPL_02531	1.81e-06	-	-	-	-	-	-	-	-
DHGKAPPL_02532	1.64e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DHGKAPPL_02533	2.06e-109	-	-	-	-	-	-	-	-
DHGKAPPL_02534	2.2e-65	-	-	-	-	-	-	-	-
DHGKAPPL_02535	2.54e-198	-	-	-	L	-	-	-	DnaD domain protein
DHGKAPPL_02536	6.25e-173	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
DHGKAPPL_02537	4.31e-198	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
DHGKAPPL_02538	8.36e-90	-	-	-	-	-	-	-	-
DHGKAPPL_02541	6.53e-121	-	-	-	-	-	-	-	-
DHGKAPPL_02543	3.14e-70	-	-	-	-	-	-	-	-
DHGKAPPL_02547	5.94e-05	-	-	-	K	-	-	-	Transcriptional
DHGKAPPL_02548	3.03e-11	-	-	-	K	-	-	-	transcriptional
DHGKAPPL_02549	5.75e-14	-	-	-	E	-	-	-	Zn peptidase
DHGKAPPL_02551	1.27e-16	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DHGKAPPL_02556	3.86e-46	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DHGKAPPL_02558	9.51e-48	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DHGKAPPL_02561	1.33e-294	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHGKAPPL_02563	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DHGKAPPL_02564	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DHGKAPPL_02565	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DHGKAPPL_02566	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DHGKAPPL_02567	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHGKAPPL_02568	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DHGKAPPL_02569	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DHGKAPPL_02570	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DHGKAPPL_02571	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
DHGKAPPL_02572	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
DHGKAPPL_02573	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHGKAPPL_02574	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DHGKAPPL_02575	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DHGKAPPL_02576	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DHGKAPPL_02577	4.91e-265	yacL	-	-	S	-	-	-	domain protein
DHGKAPPL_02578	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DHGKAPPL_02579	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DHGKAPPL_02580	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DHGKAPPL_02581	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DHGKAPPL_02582	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DHGKAPPL_02583	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
DHGKAPPL_02584	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DHGKAPPL_02585	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_02586	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
DHGKAPPL_02587	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DHGKAPPL_02588	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DHGKAPPL_02589	2.58e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DHGKAPPL_02590	4.82e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
DHGKAPPL_02591	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
DHGKAPPL_02592	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DHGKAPPL_02593	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DHGKAPPL_02594	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DHGKAPPL_02595	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
DHGKAPPL_02596	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
DHGKAPPL_02597	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
DHGKAPPL_02598	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DHGKAPPL_02599	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DHGKAPPL_02600	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DHGKAPPL_02601	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
DHGKAPPL_02602	2.77e-95	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DHGKAPPL_02603	5.04e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
DHGKAPPL_02605	7.69e-45	-	-	-	-	-	-	-	-
DHGKAPPL_02608	1.44e-134	-	-	-	LM	-	-	-	DNA recombination
DHGKAPPL_02610	3.47e-210	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DHGKAPPL_02612	5.36e-44	-	-	-	S	-	-	-	Phage tail tube protein
DHGKAPPL_02613	6.47e-29	-	-	-	-	-	-	-	-
DHGKAPPL_02614	8.77e-43	-	-	-	-	-	-	-	-
DHGKAPPL_02615	3.5e-31	-	-	-	-	-	-	-	-
DHGKAPPL_02616	3.34e-23	-	-	-	-	-	-	-	-
DHGKAPPL_02617	1.48e-139	-	-	-	S	-	-	-	Phage capsid family
DHGKAPPL_02618	2.3e-70	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
DHGKAPPL_02619	6.16e-124	-	-	-	S	-	-	-	Phage portal protein
DHGKAPPL_02620	1.41e-212	-	-	-	S	-	-	-	Terminase
DHGKAPPL_02621	7.73e-13	-	-	-	-	-	-	-	-
DHGKAPPL_02626	5.96e-42	-	-	-	-	-	-	-	-
DHGKAPPL_02628	2.37e-105	-	-	-	S	-	-	-	methyltransferase activity
DHGKAPPL_02631	8.73e-52	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
DHGKAPPL_02632	5.21e-165	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
DHGKAPPL_02633	3.33e-97	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
DHGKAPPL_02634	1.6e-28	-	-	-	-	-	-	-	-
DHGKAPPL_02635	3.29e-92	-	-	-	L	-	-	-	AAA domain
DHGKAPPL_02636	1.17e-10	-	-	-	S	-	-	-	HNH endonuclease
DHGKAPPL_02637	1.42e-216	-	-	-	S	-	-	-	helicase activity
DHGKAPPL_02638	4.51e-53	-	-	-	S	-	-	-	Siphovirus Gp157
DHGKAPPL_02645	2.01e-13	-	-	-	-	-	-	-	-
DHGKAPPL_02648	1.53e-11	-	-	-	-	-	-	-	-
DHGKAPPL_02649	5.72e-27	-	-	-	-	-	-	-	-
DHGKAPPL_02650	1.08e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHGKAPPL_02656	4.49e-119	-	-	-	S	-	-	-	T5orf172
DHGKAPPL_02657	1.43e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHGKAPPL_02659	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DHGKAPPL_02660	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DHGKAPPL_02661	7.89e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DHGKAPPL_02662	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DHGKAPPL_02663	1.27e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
DHGKAPPL_02664	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DHGKAPPL_02665	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DHGKAPPL_02666	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHGKAPPL_02667	2.31e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DHGKAPPL_02668	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DHGKAPPL_02669	8.37e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DHGKAPPL_02670	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHGKAPPL_02671	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DHGKAPPL_02672	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
DHGKAPPL_02673	3.62e-211	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
DHGKAPPL_02674	1.38e-71	-	-	-	S	-	-	-	Cupin domain
DHGKAPPL_02675	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
DHGKAPPL_02679	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DHGKAPPL_02680	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DHGKAPPL_02683	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
DHGKAPPL_02686	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DHGKAPPL_02687	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHGKAPPL_02688	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DHGKAPPL_02689	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DHGKAPPL_02690	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DHGKAPPL_02691	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DHGKAPPL_02692	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DHGKAPPL_02693	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DHGKAPPL_02695	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
DHGKAPPL_02696	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DHGKAPPL_02697	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DHGKAPPL_02698	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DHGKAPPL_02699	7.99e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DHGKAPPL_02700	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DHGKAPPL_02701	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
DHGKAPPL_02702	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
DHGKAPPL_02703	1.85e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DHGKAPPL_02704	4.47e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
DHGKAPPL_02705	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
DHGKAPPL_02706	1.38e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DHGKAPPL_02707	1.72e-242	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DHGKAPPL_02708	3.04e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DHGKAPPL_02709	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHGKAPPL_02710	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DHGKAPPL_02711	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_02712	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_02713	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DHGKAPPL_02714	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DHGKAPPL_02715	1.18e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DHGKAPPL_02716	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DHGKAPPL_02717	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DHGKAPPL_02718	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DHGKAPPL_02719	1.84e-189	-	-	-	-	-	-	-	-
DHGKAPPL_02720	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DHGKAPPL_02721	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DHGKAPPL_02722	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DHGKAPPL_02723	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
DHGKAPPL_02724	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DHGKAPPL_02725	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DHGKAPPL_02726	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHGKAPPL_02727	2.41e-37	-	-	-	-	-	-	-	-
DHGKAPPL_02728	1.89e-169	-	-	-	S	-	-	-	YheO-like PAS domain
DHGKAPPL_02729	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DHGKAPPL_02730	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
DHGKAPPL_02731	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
DHGKAPPL_02732	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DHGKAPPL_02733	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DHGKAPPL_02734	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DHGKAPPL_02735	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DHGKAPPL_02736	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
DHGKAPPL_02737	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DHGKAPPL_02738	5.9e-191	yxeH	-	-	S	-	-	-	hydrolase
DHGKAPPL_02739	7.12e-178	-	-	-	-	-	-	-	-
DHGKAPPL_02740	9.43e-235	-	-	-	S	-	-	-	DUF218 domain
DHGKAPPL_02741	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHGKAPPL_02742	3.1e-113	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DHGKAPPL_02743	1.87e-56	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DHGKAPPL_02744	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DHGKAPPL_02745	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DHGKAPPL_02746	5.3e-49	-	-	-	-	-	-	-	-
DHGKAPPL_02747	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
DHGKAPPL_02748	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DHGKAPPL_02749	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DHGKAPPL_02750	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
DHGKAPPL_02751	1.86e-208	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DHGKAPPL_02752	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
DHGKAPPL_02753	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DHGKAPPL_02754	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DHGKAPPL_02755	6.64e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DHGKAPPL_02756	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
DHGKAPPL_02757	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DHGKAPPL_02758	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
DHGKAPPL_02759	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DHGKAPPL_02760	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DHGKAPPL_02761	4.65e-229	-	-	-	-	-	-	-	-
DHGKAPPL_02762	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DHGKAPPL_02763	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHGKAPPL_02764	4.17e-193	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DHGKAPPL_02765	1.23e-262	-	-	-	-	-	-	-	-
DHGKAPPL_02766	2.94e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHGKAPPL_02767	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DHGKAPPL_02768	6.97e-209	-	-	-	GK	-	-	-	ROK family
DHGKAPPL_02769	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DHGKAPPL_02770	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02771	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DHGKAPPL_02772	9.68e-34	-	-	-	-	-	-	-	-
DHGKAPPL_02773	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02774	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DHGKAPPL_02775	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DHGKAPPL_02776	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DHGKAPPL_02777	0.0	-	-	-	L	-	-	-	DNA helicase
DHGKAPPL_02778	1.85e-40	-	-	-	-	-	-	-	-
DHGKAPPL_02779	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02780	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02781	4.14e-154	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02782	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02783	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
DHGKAPPL_02784	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DHGKAPPL_02785	8.82e-32	-	-	-	-	-	-	-	-
DHGKAPPL_02786	1.93e-31	plnF	-	-	-	-	-	-	-
DHGKAPPL_02787	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02788	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DHGKAPPL_02789	2.48e-172	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DHGKAPPL_02790	2.08e-301	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DHGKAPPL_02791	1.9e-25	plnA	-	-	-	-	-	-	-
DHGKAPPL_02792	1.43e-35	-	-	-	-	-	-	-	-
DHGKAPPL_02793	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
DHGKAPPL_02794	5.58e-291	-	-	-	M	-	-	-	Glycosyl transferase family 2
DHGKAPPL_02796	4.08e-39	-	-	-	-	-	-	-	-
DHGKAPPL_02797	8.53e-34	plnJ	-	-	-	-	-	-	-
DHGKAPPL_02798	3.29e-32	plnK	-	-	-	-	-	-	-
DHGKAPPL_02799	9.76e-153	-	-	-	-	-	-	-	-
DHGKAPPL_02800	6.24e-25	plnR	-	-	-	-	-	-	-
DHGKAPPL_02801	1.15e-43	-	-	-	-	-	-	-	-
DHGKAPPL_02803	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DHGKAPPL_02804	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DHGKAPPL_02805	8.38e-192	-	-	-	S	-	-	-	hydrolase
DHGKAPPL_02806	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02807	4.15e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
DHGKAPPL_02808	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
DHGKAPPL_02809	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHGKAPPL_02810	5.32e-51	-	-	-	-	-	-	-	-
DHGKAPPL_02811	4.92e-90	-	-	-	S	-	-	-	Immunity protein 63
DHGKAPPL_02812	2.59e-84	-	-	-	-	-	-	-	-
DHGKAPPL_02813	2.35e-52	-	-	-	-	-	-	-	-
DHGKAPPL_02814	6.97e-45	-	-	-	-	-	-	-	-
DHGKAPPL_02815	7.12e-226	-	-	-	-	-	-	-	-
DHGKAPPL_02816	6.26e-75	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
DHGKAPPL_02817	0.0	-	-	-	M	-	-	-	domain protein
DHGKAPPL_02818	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_02819	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
DHGKAPPL_02820	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DHGKAPPL_02821	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
DHGKAPPL_02822	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_02823	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DHGKAPPL_02824	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
DHGKAPPL_02825	2.82e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGKAPPL_02826	4.27e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DHGKAPPL_02827	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DHGKAPPL_02828	2.16e-103	-	-	-	-	-	-	-	-
DHGKAPPL_02829	8.37e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
DHGKAPPL_02830	3.25e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DHGKAPPL_02831	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DHGKAPPL_02832	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DHGKAPPL_02833	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DHGKAPPL_02834	1.19e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DHGKAPPL_02835	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
DHGKAPPL_02836	8.95e-60	-	-	-	-	-	-	-	-
DHGKAPPL_02837	3.66e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHGKAPPL_02838	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DHGKAPPL_02839	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
DHGKAPPL_02840	1.18e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DHGKAPPL_02841	2.76e-59	-	-	-	-	-	-	-	-
DHGKAPPL_02842	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DHGKAPPL_02843	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
DHGKAPPL_02844	1.1e-280	-	-	-	-	-	-	-	-
DHGKAPPL_02845	2.25e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHGKAPPL_02846	5.67e-187	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHGKAPPL_02847	5.18e-115	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_02848	7.98e-158	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHGKAPPL_02849	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
DHGKAPPL_02850	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
DHGKAPPL_02851	2.03e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DHGKAPPL_02852	3.1e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DHGKAPPL_02853	6.4e-54	-	-	-	-	-	-	-	-
DHGKAPPL_02854	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHGKAPPL_02855	3.48e-40	-	-	-	-	-	-	-	-
DHGKAPPL_02856	4.09e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DHGKAPPL_02857	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
DHGKAPPL_02859	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
DHGKAPPL_02860	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
DHGKAPPL_02861	1.08e-243	-	-	-	-	-	-	-	-
DHGKAPPL_02862	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_02863	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DHGKAPPL_02864	2.06e-30	-	-	-	-	-	-	-	-
DHGKAPPL_02865	1.24e-116	-	-	-	K	-	-	-	acetyltransferase
DHGKAPPL_02866	1.88e-111	-	-	-	K	-	-	-	GNAT family
DHGKAPPL_02867	8.08e-110	-	-	-	S	-	-	-	ASCH
DHGKAPPL_02868	1.5e-124	-	-	-	K	-	-	-	Cupin domain
DHGKAPPL_02869	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DHGKAPPL_02870	9e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02871	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02872	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_02873	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
DHGKAPPL_02874	1.04e-35	-	-	-	-	-	-	-	-
DHGKAPPL_02876	9.97e-50	-	-	-	-	-	-	-	-
DHGKAPPL_02877	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DHGKAPPL_02878	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02879	7.61e-102	-	-	-	S	ko:K02348	-	ko00000	GNAT family
DHGKAPPL_02880	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHGKAPPL_02881	2.03e-75	-	-	-	-	-	-	-	-
DHGKAPPL_02882	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
DHGKAPPL_02883	6.88e-170	-	-	-	-	-	-	-	-
DHGKAPPL_02884	9.03e-229	-	-	-	-	-	-	-	-
DHGKAPPL_02885	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
DHGKAPPL_02886	1.31e-97	-	-	-	M	-	-	-	LysM domain protein
DHGKAPPL_02887	7.98e-80	-	-	-	M	-	-	-	Lysin motif
DHGKAPPL_02888	2.63e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02889	9.28e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DHGKAPPL_02890	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_02891	5.27e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DHGKAPPL_02892	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
DHGKAPPL_02893	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DHGKAPPL_02894	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DHGKAPPL_02895	6.79e-135	-	-	-	K	-	-	-	transcriptional regulator
DHGKAPPL_02896	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DHGKAPPL_02897	1.49e-63	-	-	-	-	-	-	-	-
DHGKAPPL_02898	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
DHGKAPPL_02899	2.92e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DHGKAPPL_02900	2.87e-56	-	-	-	-	-	-	-	-
DHGKAPPL_02901	3.35e-75	-	-	-	-	-	-	-	-
DHGKAPPL_02902	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02903	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DHGKAPPL_02904	2.42e-65	-	-	-	-	-	-	-	-
DHGKAPPL_02905	1.1e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
DHGKAPPL_02906	9.08e-317	hpk2	-	-	T	-	-	-	Histidine kinase
DHGKAPPL_02907	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHGKAPPL_02908	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_02909	1.55e-55	-	-	-	-	-	-	-	-
DHGKAPPL_02910	2.92e-57	-	-	-	-	-	-	-	-
DHGKAPPL_02911	1.15e-152	-	-	-	-	-	-	-	-
DHGKAPPL_02912	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DHGKAPPL_02913	1.05e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_02914	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_02915	3.2e-91	-	-	-	-	-	-	-	-
DHGKAPPL_02916	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DHGKAPPL_02917	2.6e-185	-	-	-	-	-	-	-	-
DHGKAPPL_02918	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DHGKAPPL_02919	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_02920	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DHGKAPPL_02921	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DHGKAPPL_02922	2.21e-56	-	-	-	-	-	-	-	-
DHGKAPPL_02923	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
DHGKAPPL_02924	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DHGKAPPL_02925	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DHGKAPPL_02926	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DHGKAPPL_02927	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DHGKAPPL_02928	5.02e-123	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
DHGKAPPL_02929	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
DHGKAPPL_02930	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DHGKAPPL_02931	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DHGKAPPL_02932	2.98e-90	-	-	-	-	-	-	-	-
DHGKAPPL_02933	1.22e-125	-	-	-	-	-	-	-	-
DHGKAPPL_02934	3.43e-66	-	-	-	-	-	-	-	-
DHGKAPPL_02935	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DHGKAPPL_02936	1.21e-111	-	-	-	-	-	-	-	-
DHGKAPPL_02937	2.15e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
DHGKAPPL_02938	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGKAPPL_02939	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
DHGKAPPL_02940	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DHGKAPPL_02941	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHGKAPPL_02942	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
DHGKAPPL_02943	7.88e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
DHGKAPPL_02944	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
DHGKAPPL_02945	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DHGKAPPL_02946	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
DHGKAPPL_02947	1.2e-91	-	-	-	-	-	-	-	-
DHGKAPPL_02948	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHGKAPPL_02949	2.16e-201	dkgB	-	-	S	-	-	-	reductase
DHGKAPPL_02950	5.84e-115	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
DHGKAPPL_02951	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02952	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DHGKAPPL_02953	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DHGKAPPL_02955	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
DHGKAPPL_02956	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHGKAPPL_02957	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHGKAPPL_02958	3.81e-18	-	-	-	-	-	-	-	-
DHGKAPPL_02959	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHGKAPPL_02960	8.83e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
DHGKAPPL_02961	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
DHGKAPPL_02962	6.33e-46	-	-	-	-	-	-	-	-
DHGKAPPL_02963	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DHGKAPPL_02964	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
DHGKAPPL_02965	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DHGKAPPL_02966	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGKAPPL_02967	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DHGKAPPL_02968	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_02969	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_02970	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DHGKAPPL_02972	0.0	-	-	-	M	-	-	-	domain protein
DHGKAPPL_02973	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
DHGKAPPL_02974	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DHGKAPPL_02975	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DHGKAPPL_02976	5.74e-211	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DHGKAPPL_02977	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DHGKAPPL_02978	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHGKAPPL_02979	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DHGKAPPL_02980	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHGKAPPL_02981	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DHGKAPPL_02982	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DHGKAPPL_02983	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
DHGKAPPL_02984	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DHGKAPPL_02985	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DHGKAPPL_02986	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
DHGKAPPL_02987	1.75e-191	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
DHGKAPPL_02988	9.48e-205	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHGKAPPL_02989	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHGKAPPL_02990	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DHGKAPPL_02991	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
DHGKAPPL_02992	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DHGKAPPL_02993	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHGKAPPL_02994	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_02995	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
DHGKAPPL_02996	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
DHGKAPPL_02997	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
DHGKAPPL_02998	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
DHGKAPPL_02999	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_03001	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
DHGKAPPL_03002	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
DHGKAPPL_03003	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
DHGKAPPL_03004	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
DHGKAPPL_03005	1.04e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DHGKAPPL_03006	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
DHGKAPPL_03007	3.37e-115	-	-	-	-	-	-	-	-
DHGKAPPL_03008	3.16e-191	-	-	-	-	-	-	-	-
DHGKAPPL_03009	7.71e-183	-	-	-	-	-	-	-	-
DHGKAPPL_03010	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DHGKAPPL_03011	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DHGKAPPL_03012	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
DHGKAPPL_03013	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHGKAPPL_03014	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DHGKAPPL_03015	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
DHGKAPPL_03016	0.0	-	-	-	-	-	-	-	-
DHGKAPPL_03017	4.03e-132	-	-	-	-	-	-	-	-
DHGKAPPL_03018	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DHGKAPPL_03019	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
DHGKAPPL_03020	6.75e-212	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
DHGKAPPL_03021	2.52e-203	morA	-	-	S	-	-	-	reductase
DHGKAPPL_03023	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DHGKAPPL_03024	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_03025	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DHGKAPPL_03026	3.73e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DHGKAPPL_03027	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DHGKAPPL_03028	4.45e-99	-	-	-	K	-	-	-	Transcriptional regulator
DHGKAPPL_03029	2.01e-141	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
DHGKAPPL_03030	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
DHGKAPPL_03031	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DHGKAPPL_03032	2.94e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DHGKAPPL_03033	1e-156	-	-	-	-	-	-	-	-
DHGKAPPL_03034	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DHGKAPPL_03035	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DHGKAPPL_03036	0.0	-	-	-	L	-	-	-	HIRAN domain
DHGKAPPL_03037	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DHGKAPPL_03038	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DHGKAPPL_03039	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DHGKAPPL_03040	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DHGKAPPL_03041	3.77e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DHGKAPPL_03042	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DHGKAPPL_03043	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
DHGKAPPL_03044	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHGKAPPL_03045	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
DHGKAPPL_03046	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DHGKAPPL_03047	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
DHGKAPPL_03048	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
DHGKAPPL_03049	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
DHGKAPPL_03050	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
DHGKAPPL_03051	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DHGKAPPL_03052	1.43e-164	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHGKAPPL_03053	1.67e-54	-	-	-	-	-	-	-	-
DHGKAPPL_03054	2.17e-141	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
DHGKAPPL_03055	4.07e-05	-	-	-	-	-	-	-	-
DHGKAPPL_03056	4.85e-180	-	-	-	-	-	-	-	-
DHGKAPPL_03057	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DHGKAPPL_03058	2.38e-99	-	-	-	-	-	-	-	-
DHGKAPPL_03059	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DHGKAPPL_03060	3.36e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DHGKAPPL_03061	1.71e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
DHGKAPPL_03062	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DHGKAPPL_03063	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
DHGKAPPL_03064	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
DHGKAPPL_03065	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
DHGKAPPL_03066	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
DHGKAPPL_03067	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
DHGKAPPL_03068	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
DHGKAPPL_03069	0.0	fusA1	-	-	J	-	-	-	elongation factor G
DHGKAPPL_03070	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DHGKAPPL_03071	1.67e-220	-	-	-	K	-	-	-	WYL domain
DHGKAPPL_03072	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
DHGKAPPL_03073	1.65e-106	-	-	-	S	-	-	-	ASCH
DHGKAPPL_03074	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
DHGKAPPL_03075	1.14e-173	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DHGKAPPL_03076	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DHGKAPPL_03077	1.27e-247	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHGKAPPL_03078	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DHGKAPPL_03079	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
DHGKAPPL_03080	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
DHGKAPPL_03081	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
DHGKAPPL_03082	4.06e-211	-	-	-	S	-	-	-	KR domain
DHGKAPPL_03083	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DHGKAPPL_03084	2.49e-95	-	-	-	C	-	-	-	FMN binding
DHGKAPPL_03085	9.82e-203	-	-	-	K	-	-	-	LysR family
DHGKAPPL_03086	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DHGKAPPL_03087	0.0	-	-	-	C	-	-	-	FMN_bind
DHGKAPPL_03088	5.25e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
DHGKAPPL_03089	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
DHGKAPPL_03090	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
DHGKAPPL_03091	3.46e-156	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
DHGKAPPL_03092	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
DHGKAPPL_03093	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHGKAPPL_03094	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DHGKAPPL_03095	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DHGKAPPL_03096	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DHGKAPPL_03097	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
DHGKAPPL_03098	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
DHGKAPPL_03099	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHGKAPPL_03100	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DHGKAPPL_03102	2.54e-50	-	-	-	-	-	-	-	-
DHGKAPPL_03103	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
DHGKAPPL_03104	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
DHGKAPPL_03105	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
DHGKAPPL_03106	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DHGKAPPL_03107	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DHGKAPPL_03109	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DHGKAPPL_03110	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DHGKAPPL_03111	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
DHGKAPPL_03112	4.07e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
DHGKAPPL_03113	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DHGKAPPL_03114	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DHGKAPPL_03116	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
DHGKAPPL_03117	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DHGKAPPL_03118	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DHGKAPPL_03119	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
DHGKAPPL_03120	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DHGKAPPL_03121	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DHGKAPPL_03122	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DHGKAPPL_03123	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DHGKAPPL_03124	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DHGKAPPL_03125	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DHGKAPPL_03126	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHGKAPPL_03127	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHGKAPPL_03128	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP