ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NLEFIACL_00001 3.28e-231 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NLEFIACL_00002 4.31e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
NLEFIACL_00003 8.41e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NLEFIACL_00004 5.05e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NLEFIACL_00005 1.72e-129 - - - K - - - transcriptional regulator
NLEFIACL_00006 4.61e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
NLEFIACL_00007 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
NLEFIACL_00008 5.13e-138 - - - - - - - -
NLEFIACL_00010 5.77e-81 - - - - - - - -
NLEFIACL_00011 8.78e-71 - - - - - - - -
NLEFIACL_00012 1.44e-107 - - - M - - - PFAM NLP P60 protein
NLEFIACL_00013 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
NLEFIACL_00014 4.45e-38 - - - - - - - -
NLEFIACL_00015 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NLEFIACL_00016 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00017 5.33e-114 - - - K - - - Winged helix DNA-binding domain
NLEFIACL_00018 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NLEFIACL_00019 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00020 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
NLEFIACL_00021 0.0 - - - - - - - -
NLEFIACL_00022 3.42e-212 - - - S - - - Protein of unknown function (DUF1002)
NLEFIACL_00023 1.58e-66 - - - - - - - -
NLEFIACL_00024 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
NLEFIACL_00025 6.94e-117 ymdB - - S - - - Macro domain protein
NLEFIACL_00026 5.43e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NLEFIACL_00027 3.68e-57 - - - S - - - Protein of unknown function (DUF1093)
NLEFIACL_00028 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
NLEFIACL_00029 2.57e-171 - - - S - - - Putative threonine/serine exporter
NLEFIACL_00030 1.36e-209 yvgN - - C - - - Aldo keto reductase
NLEFIACL_00031 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NLEFIACL_00032 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NLEFIACL_00033 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NLEFIACL_00034 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NLEFIACL_00035 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
NLEFIACL_00036 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
NLEFIACL_00037 2.52e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NLEFIACL_00038 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NLEFIACL_00039 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
NLEFIACL_00040 2.55e-65 - - - - - - - -
NLEFIACL_00041 7.21e-35 - - - - - - - -
NLEFIACL_00042 1.77e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NLEFIACL_00043 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
NLEFIACL_00044 4.26e-54 - - - - - - - -
NLEFIACL_00045 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NLEFIACL_00046 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NLEFIACL_00047 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NLEFIACL_00048 2.55e-145 - - - S - - - VIT family
NLEFIACL_00049 2.66e-155 - - - S - - - membrane
NLEFIACL_00050 1.63e-203 - - - EG - - - EamA-like transporter family
NLEFIACL_00051 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
NLEFIACL_00052 4.17e-149 - - - GM - - - NmrA-like family
NLEFIACL_00053 4.79e-21 - - - - - - - -
NLEFIACL_00054 9.27e-74 - - - - - - - -
NLEFIACL_00055 1.31e-102 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NLEFIACL_00056 1.11e-111 - - - - - - - -
NLEFIACL_00057 2.11e-82 - - - - - - - -
NLEFIACL_00058 7.08e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NLEFIACL_00059 1.7e-70 - - - - - - - -
NLEFIACL_00060 1.41e-86 yeaO - - S - - - Protein of unknown function, DUF488
NLEFIACL_00061 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
NLEFIACL_00062 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
NLEFIACL_00063 1.12e-208 - - - GM - - - NmrA-like family
NLEFIACL_00064 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
NLEFIACL_00065 2.48e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_00066 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NLEFIACL_00067 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NLEFIACL_00068 2.63e-36 - - - S - - - Belongs to the LOG family
NLEFIACL_00069 9.84e-281 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NLEFIACL_00071 4.38e-265 - - - L - - - Transposase DDE domain
NLEFIACL_00072 7.28e-96 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NLEFIACL_00073 1.65e-166 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLEFIACL_00074 3.97e-216 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLEFIACL_00075 2.01e-127 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLEFIACL_00076 2.1e-174 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLEFIACL_00077 1.74e-156 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NLEFIACL_00079 1.44e-92 - - - M - - - Glycosyl transferases group 1
NLEFIACL_00080 1.96e-63 - - - S - - - Glycosyltransferase like family 2
NLEFIACL_00081 1.59e-67 - - - S - - - Hexapeptide repeat of succinyl-transferase
NLEFIACL_00082 2.84e-162 - - - M - - - Glycosyltransferase, group 1 family protein
NLEFIACL_00083 4.13e-122 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 3-beta hydroxysteroid dehydrogenase/isomerase family
NLEFIACL_00084 3.04e-206 - - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 glycosyl transferase group 1
NLEFIACL_00085 1.31e-65 - - - L ko:K07487 - ko00000 Transposase
NLEFIACL_00086 5.25e-78 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLEFIACL_00087 4.75e-272 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
NLEFIACL_00088 3.32e-129 tnp1216 - - L ko:K07498 - ko00000 DDE domain
NLEFIACL_00089 1.26e-90 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NLEFIACL_00090 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLEFIACL_00091 4.64e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NLEFIACL_00092 2.28e-223 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NLEFIACL_00093 5.55e-59 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
NLEFIACL_00094 2.06e-125 - - - L - - - Resolvase, N terminal domain
NLEFIACL_00095 3.21e-87 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NLEFIACL_00096 3.52e-96 - - - L - - - Transposase DDE domain
NLEFIACL_00097 8.73e-208 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NLEFIACL_00099 3.09e-79 - - - EGP - - - Major Facilitator
NLEFIACL_00100 2.87e-76 - - - S - - - Family of unknown function (DUF5388)
NLEFIACL_00101 2.13e-188 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NLEFIACL_00103 4.73e-66 repA - - S - - - Replication initiator protein A
NLEFIACL_00104 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
NLEFIACL_00105 6.43e-103 - - - - - - - -
NLEFIACL_00106 1.03e-55 - - - - - - - -
NLEFIACL_00107 6.89e-37 - - - - - - - -
NLEFIACL_00108 0.0 - - - L - - - MobA MobL family protein
NLEFIACL_00109 2.43e-49 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLEFIACL_00110 2.56e-279 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLEFIACL_00111 3.19e-45 - - - - - - - -
NLEFIACL_00112 8.28e-253 - - - L - - - Psort location Cytoplasmic, score
NLEFIACL_00113 1.09e-178 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLEFIACL_00114 3.3e-43 - - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_00115 6.14e-226 arsB - - U ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NLEFIACL_00117 1.3e-209 - - - K - - - Transcriptional regulator
NLEFIACL_00118 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NLEFIACL_00119 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NLEFIACL_00120 2.45e-101 - - - K - - - Winged helix DNA-binding domain
NLEFIACL_00121 0.0 ycaM - - E - - - amino acid
NLEFIACL_00122 2.55e-166 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
NLEFIACL_00123 4.3e-44 - - - - - - - -
NLEFIACL_00124 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NLEFIACL_00125 0.0 - - - M - - - Domain of unknown function (DUF5011)
NLEFIACL_00126 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NLEFIACL_00127 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
NLEFIACL_00128 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NLEFIACL_00129 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NLEFIACL_00130 2.8e-204 - - - EG - - - EamA-like transporter family
NLEFIACL_00131 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLEFIACL_00132 5.06e-196 - - - S - - - hydrolase
NLEFIACL_00133 7.63e-107 - - - - - - - -
NLEFIACL_00134 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
NLEFIACL_00135 1.4e-181 epsV - - S - - - glycosyl transferase family 2
NLEFIACL_00136 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
NLEFIACL_00137 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_00138 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NLEFIACL_00139 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_00140 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_00141 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NLEFIACL_00142 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NLEFIACL_00143 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_00144 2.13e-152 - - - K - - - Transcriptional regulator
NLEFIACL_00145 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLEFIACL_00146 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
NLEFIACL_00147 4.43e-294 - - - S - - - Sterol carrier protein domain
NLEFIACL_00148 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NLEFIACL_00149 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NLEFIACL_00150 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NLEFIACL_00151 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
NLEFIACL_00152 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NLEFIACL_00153 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLEFIACL_00154 2.38e-37 - - - S - - - Pentapeptide repeats (8 copies)
NLEFIACL_00155 1.1e-184 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_00156 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NLEFIACL_00157 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NLEFIACL_00159 1.42e-68 - - - - - - - -
NLEFIACL_00160 1.52e-151 - - - - - - - -
NLEFIACL_00161 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
NLEFIACL_00162 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NLEFIACL_00163 4.79e-13 - - - - - - - -
NLEFIACL_00164 1.4e-65 - - - - - - - -
NLEFIACL_00165 1.76e-114 - - - - - - - -
NLEFIACL_00166 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
NLEFIACL_00167 1.08e-47 - - - - - - - -
NLEFIACL_00168 2.7e-104 usp5 - - T - - - universal stress protein
NLEFIACL_00169 5.66e-189 - - - - - - - -
NLEFIACL_00170 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_00171 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
NLEFIACL_00172 1.94e-55 - - - - - - - -
NLEFIACL_00173 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLEFIACL_00174 2.91e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_00175 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NLEFIACL_00176 9.78e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_00177 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NLEFIACL_00178 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NLEFIACL_00179 5.76e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
NLEFIACL_00180 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
NLEFIACL_00181 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NLEFIACL_00182 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLEFIACL_00183 5.8e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLEFIACL_00184 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NLEFIACL_00185 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLEFIACL_00186 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLEFIACL_00187 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLEFIACL_00188 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLEFIACL_00189 1.04e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NLEFIACL_00190 1.79e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLEFIACL_00191 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NLEFIACL_00192 6.66e-281 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NLEFIACL_00193 3.85e-159 - - - E - - - Methionine synthase
NLEFIACL_00194 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NLEFIACL_00195 1.85e-121 - - - - - - - -
NLEFIACL_00196 1.25e-199 - - - T - - - EAL domain
NLEFIACL_00197 4.71e-208 - - - GM - - - NmrA-like family
NLEFIACL_00198 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
NLEFIACL_00199 3.62e-304 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NLEFIACL_00200 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NLEFIACL_00201 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLEFIACL_00202 1.42e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NLEFIACL_00203 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLEFIACL_00204 4.77e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NLEFIACL_00205 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NLEFIACL_00206 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLEFIACL_00207 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLEFIACL_00208 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLEFIACL_00209 4.54e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NLEFIACL_00210 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NLEFIACL_00211 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NLEFIACL_00212 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
NLEFIACL_00213 1.29e-148 - - - GM - - - NAD(P)H-binding
NLEFIACL_00214 5.73e-208 mleR - - K - - - LysR family
NLEFIACL_00215 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
NLEFIACL_00216 3.59e-26 - - - - - - - -
NLEFIACL_00217 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLEFIACL_00218 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NLEFIACL_00219 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
NLEFIACL_00220 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLEFIACL_00221 4.71e-74 - - - S - - - SdpI/YhfL protein family
NLEFIACL_00222 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
NLEFIACL_00223 8.13e-82 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_00224 5.57e-269 yttB - - EGP - - - Major Facilitator
NLEFIACL_00225 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NLEFIACL_00226 3.95e-113 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NLEFIACL_00227 0.0 yhdP - - S - - - Transporter associated domain
NLEFIACL_00228 2.97e-76 - - - - - - - -
NLEFIACL_00229 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NLEFIACL_00230 1.55e-79 - - - - - - - -
NLEFIACL_00231 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
NLEFIACL_00232 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
NLEFIACL_00233 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NLEFIACL_00234 1.18e-176 - - - - - - - -
NLEFIACL_00235 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLEFIACL_00236 3.53e-169 - - - K - - - Transcriptional regulator
NLEFIACL_00237 2.25e-206 - - - S - - - Putative esterase
NLEFIACL_00238 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NLEFIACL_00239 3.07e-284 - - - M - - - Glycosyl transferases group 1
NLEFIACL_00240 3.96e-30 - - - S - - - Protein of unknown function (DUF2929)
NLEFIACL_00241 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NLEFIACL_00242 9.66e-97 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NLEFIACL_00243 1.09e-55 - - - S - - - zinc-ribbon domain
NLEFIACL_00244 2.73e-24 - - - - - - - -
NLEFIACL_00245 8.36e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NLEFIACL_00246 1.02e-102 uspA3 - - T - - - universal stress protein
NLEFIACL_00247 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NLEFIACL_00248 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NLEFIACL_00249 4.15e-78 - - - - - - - -
NLEFIACL_00250 9.54e-97 - - - - - - - -
NLEFIACL_00251 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
NLEFIACL_00252 2.16e-63 - - - - - - - -
NLEFIACL_00253 3.89e-62 - - - - - - - -
NLEFIACL_00254 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NLEFIACL_00255 9.89e-74 ytpP - - CO - - - Thioredoxin
NLEFIACL_00256 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
NLEFIACL_00257 4.27e-89 - - - - - - - -
NLEFIACL_00258 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NLEFIACL_00259 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLEFIACL_00260 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
NLEFIACL_00261 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NLEFIACL_00262 1.88e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NLEFIACL_00263 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLEFIACL_00264 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NLEFIACL_00265 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NLEFIACL_00266 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLEFIACL_00267 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NLEFIACL_00268 5.6e-41 - - - - - - - -
NLEFIACL_00269 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NLEFIACL_00270 1.45e-131 - - - L - - - Integrase
NLEFIACL_00271 3.4e-85 - - - K - - - Winged helix DNA-binding domain
NLEFIACL_00272 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NLEFIACL_00273 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NLEFIACL_00274 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLEFIACL_00275 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLEFIACL_00276 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_00277 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
NLEFIACL_00278 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
NLEFIACL_00279 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
NLEFIACL_00280 1.49e-252 - - - M - - - MucBP domain
NLEFIACL_00281 0.0 - - - - - - - -
NLEFIACL_00282 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLEFIACL_00283 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NLEFIACL_00284 1e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NLEFIACL_00285 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NLEFIACL_00286 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NLEFIACL_00287 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NLEFIACL_00288 1.13e-257 yueF - - S - - - AI-2E family transporter
NLEFIACL_00289 4.22e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NLEFIACL_00291 5.41e-163 pbpX - - V - - - Beta-lactamase
NLEFIACL_00292 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
NLEFIACL_00293 1.62e-63 - - - K - - - sequence-specific DNA binding
NLEFIACL_00294 9.26e-171 lytE - - M - - - NlpC/P60 family
NLEFIACL_00295 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NLEFIACL_00296 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NLEFIACL_00297 3.29e-169 - - - - - - - -
NLEFIACL_00298 4.14e-132 - - - K - - - DNA-templated transcription, initiation
NLEFIACL_00299 8.39e-38 - - - - - - - -
NLEFIACL_00300 1.95e-41 - - - - - - - -
NLEFIACL_00301 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
NLEFIACL_00302 9.02e-70 - - - - - - - -
NLEFIACL_00303 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NLEFIACL_00304 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NLEFIACL_00305 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_00306 0.0 - - - M - - - domain protein
NLEFIACL_00307 2.39e-175 - - - K - - - helix_turn_helix, arabinose operon control protein
NLEFIACL_00308 8.42e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
NLEFIACL_00309 5.06e-260 cps3I - - G - - - Acyltransferase family
NLEFIACL_00310 4.9e-263 cps3H - - - - - - -
NLEFIACL_00311 1.73e-207 cps3F - - - - - - -
NLEFIACL_00312 1.69e-144 cps3E - - - - - - -
NLEFIACL_00313 1.6e-259 cps3D - - - - - - -
NLEFIACL_00314 2.81e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NLEFIACL_00315 1.56e-227 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NLEFIACL_00316 1.72e-170 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NLEFIACL_00318 6.17e-71 - - - S - - - SMI1-KNR4 cell-wall
NLEFIACL_00320 2.05e-32 - - - S - - - Barstar (barnase inhibitor)
NLEFIACL_00322 2.69e-226 - - - L ko:K07482 - ko00000 Integrase core domain
NLEFIACL_00323 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_00324 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NLEFIACL_00325 1.12e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLEFIACL_00326 4.68e-281 pbpX - - V - - - Beta-lactamase
NLEFIACL_00327 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NLEFIACL_00328 2.9e-139 - - - - - - - -
NLEFIACL_00329 7.62e-97 - - - - - - - -
NLEFIACL_00331 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_00332 7.64e-316 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_00333 3.93e-99 - - - T - - - Universal stress protein family
NLEFIACL_00335 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
NLEFIACL_00336 1.59e-244 mocA - - S - - - Oxidoreductase
NLEFIACL_00337 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NLEFIACL_00338 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
NLEFIACL_00339 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NLEFIACL_00340 5.63e-196 gntR - - K - - - rpiR family
NLEFIACL_00341 3.35e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_00342 5.55e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_00343 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NLEFIACL_00344 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00345 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLEFIACL_00346 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NLEFIACL_00347 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLEFIACL_00348 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLEFIACL_00349 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLEFIACL_00350 3.86e-262 camS - - S - - - sex pheromone
NLEFIACL_00351 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLEFIACL_00352 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NLEFIACL_00353 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLEFIACL_00354 3.79e-119 yebE - - S - - - UPF0316 protein
NLEFIACL_00355 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLEFIACL_00356 2.92e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NLEFIACL_00357 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NLEFIACL_00358 4.04e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NLEFIACL_00359 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NLEFIACL_00360 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
NLEFIACL_00361 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NLEFIACL_00362 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NLEFIACL_00363 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NLEFIACL_00364 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NLEFIACL_00365 0.0 - - - S ko:K06889 - ko00000 Alpha beta
NLEFIACL_00366 7.11e-32 - - - - - - - -
NLEFIACL_00367 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
NLEFIACL_00368 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NLEFIACL_00369 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NLEFIACL_00370 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NLEFIACL_00371 6.5e-215 mleR - - K - - - LysR family
NLEFIACL_00372 1.07e-205 mleR2 - - K - - - LysR family transcriptional regulator
NLEFIACL_00373 8.08e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NLEFIACL_00374 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NLEFIACL_00375 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NLEFIACL_00376 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NLEFIACL_00377 2.79e-184 - - - S - - - zinc-ribbon domain
NLEFIACL_00379 4.29e-50 - - - - - - - -
NLEFIACL_00380 2.78e-176 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NLEFIACL_00381 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NLEFIACL_00382 0.0 - - - I - - - acetylesterase activity
NLEFIACL_00383 1.99e-297 - - - M - - - Collagen binding domain
NLEFIACL_00384 6.92e-206 yicL - - EG - - - EamA-like transporter family
NLEFIACL_00385 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
NLEFIACL_00386 2.39e-225 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
NLEFIACL_00387 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
NLEFIACL_00388 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
NLEFIACL_00389 9.16e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLEFIACL_00390 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NLEFIACL_00391 6.37e-125 - - - K - - - Transcriptional regulator, MarR family
NLEFIACL_00392 3.29e-153 ydgI3 - - C - - - Nitroreductase family
NLEFIACL_00393 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLEFIACL_00394 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLEFIACL_00395 2.76e-196 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NLEFIACL_00396 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_00397 0.0 - - - - - - - -
NLEFIACL_00398 3.08e-80 - - - - - - - -
NLEFIACL_00399 7.52e-240 - - - S - - - Cell surface protein
NLEFIACL_00400 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00401 1.04e-111 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NLEFIACL_00402 1.61e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_00403 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NLEFIACL_00404 3.79e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NLEFIACL_00405 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NLEFIACL_00406 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NLEFIACL_00408 1.15e-43 - - - - - - - -
NLEFIACL_00409 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
NLEFIACL_00410 2.88e-106 gtcA3 - - S - - - GtrA-like protein
NLEFIACL_00411 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_00412 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NLEFIACL_00413 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
NLEFIACL_00414 7.03e-62 - - - - - - - -
NLEFIACL_00415 1.81e-150 - - - S - - - SNARE associated Golgi protein
NLEFIACL_00416 3.36e-62 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NLEFIACL_00417 2.26e-123 - - - P - - - Cadmium resistance transporter
NLEFIACL_00418 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NLEFIACL_00419 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NLEFIACL_00420 6.07e-58 - - - S - - - Cupredoxin-like domain
NLEFIACL_00421 1.36e-84 - - - S - - - Cupredoxin-like domain
NLEFIACL_00422 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NLEFIACL_00423 1.9e-179 - - - K - - - Helix-turn-helix domain
NLEFIACL_00424 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
NLEFIACL_00425 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NLEFIACL_00426 0.0 - - - - - - - -
NLEFIACL_00427 1.56e-98 - - - - - - - -
NLEFIACL_00428 1.11e-240 - - - S - - - Cell surface protein
NLEFIACL_00429 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00430 9.33e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
NLEFIACL_00431 7.09e-88 - - - S - - - Iron-sulphur cluster biosynthesis
NLEFIACL_00432 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
NLEFIACL_00433 1.59e-243 ynjC - - S - - - Cell surface protein
NLEFIACL_00434 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00435 1.47e-83 - - - - - - - -
NLEFIACL_00436 5.61e-301 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NLEFIACL_00437 4.13e-157 - - - - - - - -
NLEFIACL_00438 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
NLEFIACL_00439 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
NLEFIACL_00440 3.64e-272 - - - EGP - - - Major Facilitator
NLEFIACL_00441 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
NLEFIACL_00442 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NLEFIACL_00443 8.01e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NLEFIACL_00444 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NLEFIACL_00445 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00446 5.35e-216 - - - GM - - - NmrA-like family
NLEFIACL_00447 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NLEFIACL_00448 0.0 - - - M - - - Glycosyl hydrolases family 25
NLEFIACL_00449 3.5e-30 - - - M - - - Glycosyl hydrolases family 25
NLEFIACL_00450 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
NLEFIACL_00451 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
NLEFIACL_00452 3.27e-170 - - - S - - - KR domain
NLEFIACL_00453 6.76e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00454 5.76e-243 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
NLEFIACL_00455 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
NLEFIACL_00456 1.97e-229 ydhF - - S - - - Aldo keto reductase
NLEFIACL_00457 0.0 yfjF - - U - - - Sugar (and other) transporter
NLEFIACL_00458 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00459 3.49e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NLEFIACL_00460 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLEFIACL_00461 2.58e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLEFIACL_00462 1.11e-217 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLEFIACL_00463 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00464 8.78e-207 - - - GM - - - NmrA-like family
NLEFIACL_00465 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_00466 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NLEFIACL_00467 1.83e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NLEFIACL_00468 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_00469 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NLEFIACL_00470 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
NLEFIACL_00471 2.22e-115 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00472 1.69e-195 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NLEFIACL_00473 8.63e-72 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NLEFIACL_00474 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00475 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLEFIACL_00476 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NLEFIACL_00477 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NLEFIACL_00478 1.16e-209 - - - K - - - LysR substrate binding domain
NLEFIACL_00479 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NLEFIACL_00480 0.0 - - - S - - - MucBP domain
NLEFIACL_00481 1.49e-36 - - - - - - - -
NLEFIACL_00482 0.0 traA - - L - - - MobA MobL family protein
NLEFIACL_00483 4.98e-225 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLEFIACL_00484 6.76e-170 epsB - - M - - - biosynthesis protein
NLEFIACL_00485 4.78e-163 ywqD - - D - - - Capsular exopolysaccharide family
NLEFIACL_00486 1.32e-172 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NLEFIACL_00487 6.38e-34 - - - L - - - Transposase and inactivated derivatives, IS30 family
NLEFIACL_00488 6.93e-166 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NLEFIACL_00489 7e-259 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NLEFIACL_00490 6.21e-39 - - - - - - - -
NLEFIACL_00491 2.43e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NLEFIACL_00492 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLEFIACL_00493 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
NLEFIACL_00494 6.45e-111 - - - - - - - -
NLEFIACL_00495 2.29e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLEFIACL_00496 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NLEFIACL_00497 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NLEFIACL_00498 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLEFIACL_00499 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NLEFIACL_00500 1.24e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NLEFIACL_00501 6.24e-61 yktA - - S - - - Belongs to the UPF0223 family
NLEFIACL_00502 1.43e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NLEFIACL_00503 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NLEFIACL_00504 4.74e-152 icaA - - M - - - Glycosyl transferase family group 2
NLEFIACL_00505 0.0 - - - - - - - -
NLEFIACL_00506 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NLEFIACL_00507 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NLEFIACL_00508 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NLEFIACL_00509 6.06e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NLEFIACL_00510 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLEFIACL_00511 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NLEFIACL_00512 3.85e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NLEFIACL_00513 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NLEFIACL_00514 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NLEFIACL_00515 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NLEFIACL_00516 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NLEFIACL_00517 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLEFIACL_00518 1.82e-260 - - - EGP - - - Major Facilitator Superfamily
NLEFIACL_00519 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLEFIACL_00520 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLEFIACL_00521 5.89e-204 - - - S - - - Tetratricopeptide repeat
NLEFIACL_00522 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLEFIACL_00523 6.48e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLEFIACL_00524 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLEFIACL_00525 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NLEFIACL_00526 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
NLEFIACL_00527 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
NLEFIACL_00528 5.12e-31 - - - - - - - -
NLEFIACL_00529 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NLEFIACL_00530 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_00531 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLEFIACL_00532 8.45e-162 epsB - - M - - - biosynthesis protein
NLEFIACL_00533 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
NLEFIACL_00534 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NLEFIACL_00535 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NLEFIACL_00536 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
NLEFIACL_00537 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
NLEFIACL_00538 1.99e-237 cps4G - - M - - - Glycosyltransferase Family 4
NLEFIACL_00539 3.68e-295 - - - - - - - -
NLEFIACL_00540 9.73e-228 cps4I - - M - - - Glycosyltransferase like family 2
NLEFIACL_00541 0.0 cps4J - - S - - - MatE
NLEFIACL_00542 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NLEFIACL_00543 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NLEFIACL_00544 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NLEFIACL_00545 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NLEFIACL_00546 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLEFIACL_00547 6.62e-62 - - - - - - - -
NLEFIACL_00548 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLEFIACL_00549 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_00550 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
NLEFIACL_00551 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NLEFIACL_00552 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLEFIACL_00553 7.9e-136 - - - K - - - Helix-turn-helix domain
NLEFIACL_00554 2.87e-270 - - - EGP - - - Major facilitator Superfamily
NLEFIACL_00555 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
NLEFIACL_00556 1.14e-180 - - - Q - - - Methyltransferase
NLEFIACL_00557 1.75e-43 - - - - - - - -
NLEFIACL_00560 1.54e-50 int2 - - L - - - Belongs to the 'phage' integrase family
NLEFIACL_00561 1.01e-42 - - - L ko:K07483 - ko00000 transposase activity
NLEFIACL_00562 2.14e-53 - - - L - - - HTH-like domain
NLEFIACL_00563 5.48e-05 - - - S - - - Short C-terminal domain
NLEFIACL_00564 4.86e-19 - - - S - - - Short C-terminal domain
NLEFIACL_00565 2.83e-46 - - - - - - - -
NLEFIACL_00566 9.63e-17 - - - - - - - -
NLEFIACL_00567 1.67e-139 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NLEFIACL_00568 5.57e-91 tnpR1 - - L - - - Resolvase, N terminal domain
NLEFIACL_00569 1.59e-57 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase type I activity
NLEFIACL_00570 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 C-terminal repeat of topoisomerase
NLEFIACL_00571 8.36e-64 - - - - - - - -
NLEFIACL_00572 2.47e-37 - - - - - - - -
NLEFIACL_00573 2.81e-284 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
NLEFIACL_00574 2.64e-45 - - - - - - - -
NLEFIACL_00575 6.54e-38 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NLEFIACL_00576 6.92e-68 - - - - - - - -
NLEFIACL_00577 3.56e-140 - - - M - - - CHAP domain
NLEFIACL_00578 1.53e-187 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
NLEFIACL_00579 0.0 - - - U - - - AAA-like domain
NLEFIACL_00580 1.08e-122 - - - - - - - -
NLEFIACL_00581 7.09e-36 - - - - - - - -
NLEFIACL_00582 4.92e-50 - - - S - - - Cag pathogenicity island, type IV secretory system
NLEFIACL_00583 2.98e-76 - - - - - - - -
NLEFIACL_00584 1.02e-26 - - - - - - - -
NLEFIACL_00585 1.36e-284 traA - - L - - - MobA MobL family protein
NLEFIACL_00587 1.16e-26 - - - - - - - -
NLEFIACL_00590 1.46e-170 - - - - - - - -
NLEFIACL_00591 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
NLEFIACL_00592 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NLEFIACL_00593 7.79e-112 - - - K - - - MerR HTH family regulatory protein
NLEFIACL_00594 1.36e-77 - - - - - - - -
NLEFIACL_00595 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NLEFIACL_00596 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NLEFIACL_00597 4.6e-169 - - - S - - - Putative threonine/serine exporter
NLEFIACL_00598 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
NLEFIACL_00599 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NLEFIACL_00600 2.05e-153 - - - I - - - phosphatase
NLEFIACL_00601 3.88e-198 - - - I - - - alpha/beta hydrolase fold
NLEFIACL_00602 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NLEFIACL_00603 1.7e-118 - - - K - - - Transcriptional regulator
NLEFIACL_00604 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NLEFIACL_00605 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NLEFIACL_00606 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NLEFIACL_00607 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
NLEFIACL_00608 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLEFIACL_00616 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NLEFIACL_00617 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLEFIACL_00618 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00619 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLEFIACL_00620 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLEFIACL_00621 1.66e-146 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NLEFIACL_00622 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLEFIACL_00623 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLEFIACL_00624 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLEFIACL_00625 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NLEFIACL_00626 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLEFIACL_00627 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NLEFIACL_00628 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLEFIACL_00629 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLEFIACL_00630 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLEFIACL_00631 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLEFIACL_00632 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLEFIACL_00633 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLEFIACL_00634 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NLEFIACL_00635 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLEFIACL_00636 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLEFIACL_00637 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLEFIACL_00638 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLEFIACL_00639 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLEFIACL_00640 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLEFIACL_00641 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLEFIACL_00642 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLEFIACL_00643 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NLEFIACL_00644 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NLEFIACL_00645 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLEFIACL_00646 5.28e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLEFIACL_00647 1.99e-44 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLEFIACL_00648 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLEFIACL_00649 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLEFIACL_00650 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLEFIACL_00651 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NLEFIACL_00652 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NLEFIACL_00653 1.65e-121 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NLEFIACL_00654 5.37e-112 - - - S - - - NusG domain II
NLEFIACL_00655 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NLEFIACL_00656 3.19e-194 - - - S - - - FMN_bind
NLEFIACL_00657 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLEFIACL_00658 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLEFIACL_00659 8.18e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLEFIACL_00660 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLEFIACL_00661 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLEFIACL_00662 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLEFIACL_00663 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NLEFIACL_00664 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NLEFIACL_00665 5.79e-234 - - - S - - - Membrane
NLEFIACL_00666 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NLEFIACL_00667 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLEFIACL_00668 6.73e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLEFIACL_00669 4.68e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
NLEFIACL_00670 2.03e-250 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLEFIACL_00671 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NLEFIACL_00672 6.15e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
NLEFIACL_00673 2.01e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
NLEFIACL_00674 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
NLEFIACL_00675 6.33e-254 - - - K - - - Helix-turn-helix domain
NLEFIACL_00676 5.24e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NLEFIACL_00677 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLEFIACL_00678 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NLEFIACL_00679 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NLEFIACL_00680 1.18e-66 - - - - - - - -
NLEFIACL_00681 1.07e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NLEFIACL_00682 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NLEFIACL_00683 8.69e-230 citR - - K - - - sugar-binding domain protein
NLEFIACL_00684 5.51e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NLEFIACL_00685 1.07e-241 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NLEFIACL_00686 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NLEFIACL_00687 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NLEFIACL_00688 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NLEFIACL_00689 5.69e-185 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NLEFIACL_00690 6.87e-33 - - - K - - - sequence-specific DNA binding
NLEFIACL_00694 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NLEFIACL_00695 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
NLEFIACL_00699 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
NLEFIACL_00700 1.38e-71 - - - S - - - Cupin domain
NLEFIACL_00701 3.62e-211 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
NLEFIACL_00702 1.59e-247 ysdE - - P - - - Citrate transporter
NLEFIACL_00703 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NLEFIACL_00704 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLEFIACL_00705 8.37e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLEFIACL_00706 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NLEFIACL_00707 2.31e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NLEFIACL_00708 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLEFIACL_00709 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLEFIACL_00710 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NLEFIACL_00711 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
NLEFIACL_00712 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NLEFIACL_00713 7.89e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NLEFIACL_00714 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NLEFIACL_00715 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLEFIACL_00717 1e-200 - - - G - - - Peptidase_C39 like family
NLEFIACL_00718 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NLEFIACL_00719 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NLEFIACL_00720 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NLEFIACL_00721 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
NLEFIACL_00722 0.0 levR - - K - - - Sigma-54 interaction domain
NLEFIACL_00723 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NLEFIACL_00724 1.83e-112 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NLEFIACL_00725 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLEFIACL_00726 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
NLEFIACL_00727 4.82e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
NLEFIACL_00728 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLEFIACL_00729 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NLEFIACL_00730 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NLEFIACL_00731 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NLEFIACL_00732 6.04e-227 - - - EG - - - EamA-like transporter family
NLEFIACL_00733 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLEFIACL_00734 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
NLEFIACL_00735 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NLEFIACL_00736 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLEFIACL_00737 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NLEFIACL_00738 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NLEFIACL_00739 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLEFIACL_00740 4.91e-265 yacL - - S - - - domain protein
NLEFIACL_00741 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLEFIACL_00742 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NLEFIACL_00743 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLEFIACL_00744 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLEFIACL_00745 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NLEFIACL_00746 3.22e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
NLEFIACL_00747 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NLEFIACL_00748 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLEFIACL_00749 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NLEFIACL_00750 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_00751 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLEFIACL_00752 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLEFIACL_00753 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLEFIACL_00754 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLEFIACL_00756 6.57e-295 - - - L - - - Belongs to the 'phage' integrase family
NLEFIACL_00761 5.43e-244 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NLEFIACL_00765 2.91e-08 - - - K - - - Cro/C1-type HTH DNA-binding domain
NLEFIACL_00769 9.27e-121 - - - - - - - -
NLEFIACL_00772 2.4e-89 - - - - - - - -
NLEFIACL_00773 7.14e-197 - - - L ko:K07455 - ko00000,ko03400 RecT family
NLEFIACL_00774 1.87e-174 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NLEFIACL_00775 9.96e-43 - - - L - - - Domain of unknown function (DUF4373)
NLEFIACL_00776 2.91e-192 - - - S - - - IstB-like ATP binding protein
NLEFIACL_00778 4.5e-113 - - - - - - - -
NLEFIACL_00779 5.91e-85 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NLEFIACL_00784 1.35e-13 - - - S - - - YopX protein
NLEFIACL_00785 2.15e-106 - - - S - - - Phage transcriptional regulator, ArpU family
NLEFIACL_00789 5.64e-25 - - - - - - - -
NLEFIACL_00791 9.87e-132 - - - L ko:K07474 - ko00000 Terminase small subunit
NLEFIACL_00792 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
NLEFIACL_00793 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NLEFIACL_00794 1.75e-226 - - - S - - - Phage Mu protein F like protein
NLEFIACL_00795 1.38e-112 - - - S - - - Domain of unknown function (DUF4355)
NLEFIACL_00796 1.1e-257 gpG - - - - - - -
NLEFIACL_00797 1.73e-81 - - - S - - - Phage gp6-like head-tail connector protein
NLEFIACL_00798 7.48e-74 - - - - - - - -
NLEFIACL_00799 2.57e-127 - - - - - - - -
NLEFIACL_00800 1.9e-86 - - - - - - - -
NLEFIACL_00801 2.55e-137 - - - - - - - -
NLEFIACL_00802 1.41e-115 - - - S - - - Phage tail assembly chaperone protein, TAC
NLEFIACL_00804 0.0 - - - D - - - domain protein
NLEFIACL_00805 1.19e-182 - - - S - - - phage tail
NLEFIACL_00806 0.0 - - - M - - - Prophage endopeptidase tail
NLEFIACL_00807 3.46e-241 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NLEFIACL_00808 1.92e-141 - - - S - - - Domain of unknown function (DUF2479)
NLEFIACL_00811 2.56e-34 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
NLEFIACL_00812 4.47e-230 - - - M - - - hydrolase, family 25
NLEFIACL_00813 5.96e-46 - - - S - - - Haemolysin XhlA
NLEFIACL_00814 3.7e-56 - - - S - - - Bacteriophage holin
NLEFIACL_00815 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NLEFIACL_00816 1.78e-88 - - - L - - - nuclease
NLEFIACL_00817 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLEFIACL_00818 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NLEFIACL_00819 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLEFIACL_00820 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLEFIACL_00821 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NLEFIACL_00822 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NLEFIACL_00823 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLEFIACL_00824 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLEFIACL_00825 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLEFIACL_00826 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLEFIACL_00827 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
NLEFIACL_00828 1.91e-297 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_00829 4.97e-67 - 2.7.1.194 - G ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_00830 2.27e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_00831 4.67e-280 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NLEFIACL_00832 1.16e-128 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NLEFIACL_00833 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLEFIACL_00834 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
NLEFIACL_00835 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NLEFIACL_00836 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
NLEFIACL_00837 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLEFIACL_00838 1.84e-190 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NLEFIACL_00839 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NLEFIACL_00840 5.35e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NLEFIACL_00841 1.14e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
NLEFIACL_00842 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_00843 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
NLEFIACL_00844 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NLEFIACL_00845 2.84e-241 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NLEFIACL_00846 3.95e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NLEFIACL_00847 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NLEFIACL_00848 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NLEFIACL_00849 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLEFIACL_00850 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLEFIACL_00851 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NLEFIACL_00852 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLEFIACL_00853 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLEFIACL_00854 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLEFIACL_00855 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
NLEFIACL_00856 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NLEFIACL_00857 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLEFIACL_00858 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NLEFIACL_00859 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLEFIACL_00860 1.21e-129 - - - S - - - SdpI/YhfL protein family
NLEFIACL_00861 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLEFIACL_00862 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NLEFIACL_00863 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NLEFIACL_00864 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NLEFIACL_00865 1.38e-155 csrR - - K - - - response regulator
NLEFIACL_00866 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NLEFIACL_00867 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLEFIACL_00868 8.93e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLEFIACL_00869 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
NLEFIACL_00870 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NLEFIACL_00871 3.55e-279 ylbM - - S - - - Belongs to the UPF0348 family
NLEFIACL_00872 1.57e-178 yqeM - - Q - - - Methyltransferase
NLEFIACL_00873 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLEFIACL_00874 1.71e-149 yqeK - - H - - - Hydrolase, HD family
NLEFIACL_00875 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLEFIACL_00876 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NLEFIACL_00877 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NLEFIACL_00878 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NLEFIACL_00879 1.81e-113 - - - - - - - -
NLEFIACL_00880 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NLEFIACL_00881 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NLEFIACL_00882 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
NLEFIACL_00883 6.92e-76 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NLEFIACL_00884 4.34e-156 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NLEFIACL_00885 8.2e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NLEFIACL_00886 2.76e-74 - - - - - - - -
NLEFIACL_00887 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLEFIACL_00888 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NLEFIACL_00889 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLEFIACL_00890 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLEFIACL_00891 4.97e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NLEFIACL_00892 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NLEFIACL_00893 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLEFIACL_00894 3.88e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLEFIACL_00895 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLEFIACL_00896 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLEFIACL_00897 3.46e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NLEFIACL_00898 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NLEFIACL_00899 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
NLEFIACL_00900 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NLEFIACL_00901 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NLEFIACL_00902 1.83e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLEFIACL_00903 8.63e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NLEFIACL_00904 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NLEFIACL_00905 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NLEFIACL_00906 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NLEFIACL_00907 3.04e-29 - - - S - - - Virus attachment protein p12 family
NLEFIACL_00908 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NLEFIACL_00909 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NLEFIACL_00910 1.69e-144 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLEFIACL_00911 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
NLEFIACL_00912 1.92e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLEFIACL_00913 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
NLEFIACL_00914 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_00915 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_00916 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NLEFIACL_00917 7.9e-72 - - - - - - - -
NLEFIACL_00918 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NLEFIACL_00919 1.35e-133 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00920 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_00921 3.36e-248 - - - S - - - Fn3-like domain
NLEFIACL_00922 4.75e-80 - - - - - - - -
NLEFIACL_00923 0.0 - - - - - - - -
NLEFIACL_00924 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NLEFIACL_00925 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_00926 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NLEFIACL_00927 3.39e-138 - - - - - - - -
NLEFIACL_00928 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
NLEFIACL_00929 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NLEFIACL_00930 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NLEFIACL_00931 2.5e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NLEFIACL_00932 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NLEFIACL_00933 0.0 - - - S - - - membrane
NLEFIACL_00934 2.24e-87 - - - S - - - NUDIX domain
NLEFIACL_00935 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLEFIACL_00936 3.85e-234 ykoT - - M - - - Glycosyl transferase family 2
NLEFIACL_00937 0.0 - - - L - - - MutS domain V
NLEFIACL_00938 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
NLEFIACL_00939 4.09e-253 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLEFIACL_00941 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NLEFIACL_00942 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NLEFIACL_00944 6.21e-121 repE - - K - - - Primase C terminal 1 (PriCT-1)
NLEFIACL_00945 2.7e-79 - - - D - - - AAA domain
NLEFIACL_00947 3.31e-148 - - - L ko:K07482 - ko00000 Integrase core domain
NLEFIACL_00948 1.89e-101 - - - - - - - -
NLEFIACL_00949 1.08e-138 - - - L - - - Integrase
NLEFIACL_00950 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
NLEFIACL_00951 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NLEFIACL_00952 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NLEFIACL_00954 3.14e-57 - - - M - - - LPXTG-motif cell wall anchor domain protein
NLEFIACL_00955 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NLEFIACL_00956 1.1e-112 - - - - - - - -
NLEFIACL_00957 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NLEFIACL_00958 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NLEFIACL_00960 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
NLEFIACL_00961 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
NLEFIACL_00962 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLEFIACL_00963 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NLEFIACL_00964 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NLEFIACL_00965 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NLEFIACL_00966 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NLEFIACL_00967 1.45e-126 entB - - Q - - - Isochorismatase family
NLEFIACL_00968 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
NLEFIACL_00969 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
NLEFIACL_00970 1.62e-276 - - - E - - - glutamate:sodium symporter activity
NLEFIACL_00971 1.38e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
NLEFIACL_00972 3.01e-249 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NLEFIACL_00973 2.47e-76 - - - S - - - Protein of unknown function (DUF1648)
NLEFIACL_00974 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_00975 8.02e-230 yneE - - K - - - Transcriptional regulator
NLEFIACL_00976 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLEFIACL_00977 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLEFIACL_00978 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLEFIACL_00979 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NLEFIACL_00980 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NLEFIACL_00981 3.11e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLEFIACL_00982 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLEFIACL_00983 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NLEFIACL_00984 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NLEFIACL_00985 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLEFIACL_00986 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NLEFIACL_00987 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NLEFIACL_00988 1.01e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NLEFIACL_00989 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NLEFIACL_00990 1.07e-206 - - - K - - - LysR substrate binding domain
NLEFIACL_00991 4.94e-114 ykhA - - I - - - Thioesterase superfamily
NLEFIACL_00992 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLEFIACL_00993 1e-119 - - - K - - - transcriptional regulator
NLEFIACL_00994 0.0 - - - EGP - - - Major Facilitator
NLEFIACL_00995 6.56e-193 - - - O - - - Band 7 protein
NLEFIACL_00996 8.14e-47 - - - L - - - Pfam:Integrase_AP2
NLEFIACL_01000 1.19e-13 - - - - - - - -
NLEFIACL_01002 2.1e-71 - - - - - - - -
NLEFIACL_01003 1.42e-39 - - - - - - - -
NLEFIACL_01004 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NLEFIACL_01005 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
NLEFIACL_01006 3.16e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NLEFIACL_01007 2.05e-55 - - - - - - - -
NLEFIACL_01008 4.98e-107 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
NLEFIACL_01009 3.05e-99 - - - T - - - Belongs to the universal stress protein A family
NLEFIACL_01010 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
NLEFIACL_01011 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
NLEFIACL_01012 1.51e-48 - - - - - - - -
NLEFIACL_01013 5.79e-21 - - - - - - - -
NLEFIACL_01014 2.22e-55 - - - S - - - transglycosylase associated protein
NLEFIACL_01015 4e-40 - - - S - - - CsbD-like
NLEFIACL_01016 1.06e-53 - - - - - - - -
NLEFIACL_01017 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NLEFIACL_01018 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NLEFIACL_01019 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLEFIACL_01020 1.22e-217 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NLEFIACL_01021 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
NLEFIACL_01022 1.65e-38 - - - - - - - -
NLEFIACL_01023 2.12e-57 - - - - - - - -
NLEFIACL_01024 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLEFIACL_01025 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NLEFIACL_01026 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NLEFIACL_01027 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NLEFIACL_01028 1.68e-157 - - - S - - - Domain of unknown function (DUF4767)
NLEFIACL_01029 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NLEFIACL_01030 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NLEFIACL_01031 3.76e-244 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NLEFIACL_01032 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLEFIACL_01033 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NLEFIACL_01034 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NLEFIACL_01035 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NLEFIACL_01036 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NLEFIACL_01037 2.53e-107 ypmB - - S - - - protein conserved in bacteria
NLEFIACL_01038 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NLEFIACL_01039 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NLEFIACL_01040 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
NLEFIACL_01042 9.85e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLEFIACL_01043 8.18e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_01044 5.51e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NLEFIACL_01045 1.31e-109 - - - T - - - Universal stress protein family
NLEFIACL_01046 2.81e-140 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_01047 7.35e-155 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_01048 4.86e-235 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLEFIACL_01049 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLEFIACL_01050 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NLEFIACL_01051 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLEFIACL_01052 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
NLEFIACL_01053 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLEFIACL_01055 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NLEFIACL_01056 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_01057 3.65e-308 - - - P - - - Major Facilitator Superfamily
NLEFIACL_01058 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NLEFIACL_01059 2.26e-95 - - - S - - - SnoaL-like domain
NLEFIACL_01060 1.59e-254 - - - M - - - Glycosyltransferase, group 2 family protein
NLEFIACL_01061 3.32e-265 mccF - - V - - - LD-carboxypeptidase
NLEFIACL_01062 1.66e-61 - - - K - - - Acetyltransferase (GNAT) domain
NLEFIACL_01063 5.01e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
NLEFIACL_01064 1.44e-234 - - - V - - - LD-carboxypeptidase
NLEFIACL_01065 8.41e-97 XK27_05710 - - K - - - Acetyltransferase (GNAT) domain
NLEFIACL_01066 5.46e-157 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NLEFIACL_01067 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLEFIACL_01068 6.79e-249 - - - - - - - -
NLEFIACL_01069 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
NLEFIACL_01070 9.95e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
NLEFIACL_01071 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NLEFIACL_01072 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
NLEFIACL_01073 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NLEFIACL_01074 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLEFIACL_01075 1.96e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NLEFIACL_01076 1.1e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLEFIACL_01077 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NLEFIACL_01078 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NLEFIACL_01079 0.0 - - - S - - - Bacterial membrane protein, YfhO
NLEFIACL_01080 4.75e-144 - - - G - - - Phosphoglycerate mutase family
NLEFIACL_01081 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NLEFIACL_01083 7.51e-166 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
NLEFIACL_01084 8.49e-92 - - - S - - - LuxR family transcriptional regulator
NLEFIACL_01085 2.31e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NLEFIACL_01087 5.37e-117 - - - F - - - NUDIX domain
NLEFIACL_01088 2.42e-71 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01089 0.0 FbpA - - K - - - Fibronectin-binding protein
NLEFIACL_01090 1.97e-87 - - - K - - - Transcriptional regulator
NLEFIACL_01091 1.11e-205 - - - S - - - EDD domain protein, DegV family
NLEFIACL_01092 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NLEFIACL_01093 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
NLEFIACL_01094 3.72e-38 - - - - - - - -
NLEFIACL_01095 2.37e-65 - - - - - - - -
NLEFIACL_01096 2.82e-190 - - - C - - - Domain of unknown function (DUF4931)
NLEFIACL_01097 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
NLEFIACL_01099 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NLEFIACL_01100 6.02e-166 yejC - - S - - - Protein of unknown function (DUF1003)
NLEFIACL_01101 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NLEFIACL_01102 2.14e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NLEFIACL_01103 2.79e-181 - - - - - - - -
NLEFIACL_01104 7.79e-78 - - - - - - - -
NLEFIACL_01105 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NLEFIACL_01106 7.87e-289 - - - - - - - -
NLEFIACL_01107 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NLEFIACL_01108 2.44e-242 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NLEFIACL_01109 1.66e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NLEFIACL_01110 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NLEFIACL_01111 1.34e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NLEFIACL_01112 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_01113 7.91e-305 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NLEFIACL_01114 3.81e-64 - - - - - - - -
NLEFIACL_01115 4.8e-310 - - - M - - - Glycosyl transferase family group 2
NLEFIACL_01116 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLEFIACL_01117 1.03e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
NLEFIACL_01118 1.07e-43 - - - S - - - YozE SAM-like fold
NLEFIACL_01119 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLEFIACL_01120 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NLEFIACL_01121 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NLEFIACL_01122 3.82e-228 - - - K - - - Transcriptional regulator
NLEFIACL_01123 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLEFIACL_01124 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLEFIACL_01125 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLEFIACL_01126 7.34e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NLEFIACL_01127 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NLEFIACL_01128 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NLEFIACL_01129 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NLEFIACL_01130 9.43e-317 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLEFIACL_01131 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLEFIACL_01132 5.03e-178 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NLEFIACL_01133 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLEFIACL_01134 1.07e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLEFIACL_01135 5.13e-292 XK27_05470 - - E - - - Methionine synthase
NLEFIACL_01136 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
NLEFIACL_01137 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
NLEFIACL_01138 1.75e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NLEFIACL_01139 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
NLEFIACL_01140 0.0 qacA - - EGP - - - Major Facilitator
NLEFIACL_01141 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NLEFIACL_01142 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
NLEFIACL_01143 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NLEFIACL_01144 1.19e-208 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NLEFIACL_01145 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
NLEFIACL_01146 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLEFIACL_01147 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLEFIACL_01148 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01149 6.46e-109 - - - - - - - -
NLEFIACL_01150 4.25e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLEFIACL_01151 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLEFIACL_01152 3.71e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NLEFIACL_01153 5.96e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NLEFIACL_01154 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLEFIACL_01155 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NLEFIACL_01156 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NLEFIACL_01157 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NLEFIACL_01158 1.25e-39 - - - M - - - Lysin motif
NLEFIACL_01159 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NLEFIACL_01160 5.38e-249 - - - S - - - Helix-turn-helix domain
NLEFIACL_01161 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLEFIACL_01162 4.62e-151 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NLEFIACL_01163 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLEFIACL_01164 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLEFIACL_01165 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLEFIACL_01166 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NLEFIACL_01167 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
NLEFIACL_01168 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
NLEFIACL_01169 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NLEFIACL_01170 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLEFIACL_01171 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NLEFIACL_01172 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
NLEFIACL_01174 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLEFIACL_01175 1.29e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NLEFIACL_01176 6.55e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLEFIACL_01177 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NLEFIACL_01178 4.8e-293 - - - M - - - O-Antigen ligase
NLEFIACL_01179 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NLEFIACL_01180 5.71e-211 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_01181 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_01182 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NLEFIACL_01183 1.94e-83 - - - P - - - Rhodanese Homology Domain
NLEFIACL_01184 2.13e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_01185 1.02e-261 - - - - - - - -
NLEFIACL_01186 6.08e-277 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NLEFIACL_01187 5.25e-233 - - - C - - - Zinc-binding dehydrogenase
NLEFIACL_01188 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NLEFIACL_01189 4.44e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLEFIACL_01190 2.18e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NLEFIACL_01191 4.38e-102 - - - K - - - Transcriptional regulator
NLEFIACL_01192 3.73e-264 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NLEFIACL_01193 2.69e-234 tanA - - S - - - alpha beta
NLEFIACL_01194 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLEFIACL_01195 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NLEFIACL_01196 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NLEFIACL_01197 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
NLEFIACL_01198 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
NLEFIACL_01199 5.7e-146 - - - GM - - - epimerase
NLEFIACL_01200 2.06e-164 - - - S - - - Zinc finger, swim domain protein
NLEFIACL_01201 2.6e-227 - - - S - - - Zinc finger, swim domain protein
NLEFIACL_01202 4.31e-105 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_01203 1.12e-273 - - - S - - - membrane
NLEFIACL_01204 1.55e-07 - - - K - - - transcriptional regulator
NLEFIACL_01205 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_01206 8.34e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_01207 4.35e-146 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NLEFIACL_01208 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NLEFIACL_01209 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
NLEFIACL_01210 2.63e-206 - - - S - - - Alpha beta hydrolase
NLEFIACL_01211 1.02e-145 - - - GM - - - NmrA-like family
NLEFIACL_01212 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
NLEFIACL_01213 5.72e-207 - - - K - - - Transcriptional regulator
NLEFIACL_01214 2.66e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NLEFIACL_01216 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLEFIACL_01217 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NLEFIACL_01218 2.08e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NLEFIACL_01219 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NLEFIACL_01220 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_01222 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NLEFIACL_01223 3.89e-94 - - - K - - - MarR family
NLEFIACL_01224 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
NLEFIACL_01225 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
NLEFIACL_01226 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01227 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NLEFIACL_01228 2.48e-252 - - - - - - - -
NLEFIACL_01229 5.01e-254 - - - - - - - -
NLEFIACL_01230 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01231 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NLEFIACL_01232 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLEFIACL_01233 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLEFIACL_01234 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NLEFIACL_01235 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NLEFIACL_01236 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NLEFIACL_01237 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLEFIACL_01238 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NLEFIACL_01239 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLEFIACL_01240 9.71e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NLEFIACL_01241 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NLEFIACL_01242 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NLEFIACL_01243 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NLEFIACL_01244 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
NLEFIACL_01245 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NLEFIACL_01246 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NLEFIACL_01247 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLEFIACL_01248 2.15e-131 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLEFIACL_01249 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NLEFIACL_01250 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NLEFIACL_01251 1.15e-199 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NLEFIACL_01252 2.65e-213 - - - G - - - Fructosamine kinase
NLEFIACL_01253 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
NLEFIACL_01254 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLEFIACL_01255 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLEFIACL_01256 2.56e-76 - - - - - - - -
NLEFIACL_01257 1.27e-171 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLEFIACL_01258 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NLEFIACL_01259 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NLEFIACL_01260 4.78e-65 - - - - - - - -
NLEFIACL_01261 1.73e-67 - - - - - - - -
NLEFIACL_01262 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLEFIACL_01263 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLEFIACL_01264 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLEFIACL_01265 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NLEFIACL_01266 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLEFIACL_01267 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NLEFIACL_01268 8.49e-266 pbpX2 - - V - - - Beta-lactamase
NLEFIACL_01269 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLEFIACL_01270 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NLEFIACL_01271 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLEFIACL_01272 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLEFIACL_01273 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NLEFIACL_01274 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NLEFIACL_01275 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLEFIACL_01276 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NLEFIACL_01277 5.99e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NLEFIACL_01278 6.72e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NLEFIACL_01279 3.56e-97 - - - - - - - -
NLEFIACL_01280 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLEFIACL_01281 0.0 - - - G - - - Major Facilitator
NLEFIACL_01282 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLEFIACL_01283 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLEFIACL_01284 3.28e-63 ylxQ - - J - - - ribosomal protein
NLEFIACL_01285 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NLEFIACL_01286 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NLEFIACL_01287 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NLEFIACL_01288 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLEFIACL_01289 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLEFIACL_01290 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NLEFIACL_01291 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NLEFIACL_01292 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLEFIACL_01293 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLEFIACL_01294 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NLEFIACL_01295 1.55e-193 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLEFIACL_01296 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NLEFIACL_01297 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NLEFIACL_01298 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLEFIACL_01299 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NLEFIACL_01300 3.65e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NLEFIACL_01301 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NLEFIACL_01302 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NLEFIACL_01303 7.68e-48 ynzC - - S - - - UPF0291 protein
NLEFIACL_01304 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLEFIACL_01305 1.83e-121 - - - - - - - -
NLEFIACL_01306 6.62e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NLEFIACL_01307 1.01e-100 - - - - - - - -
NLEFIACL_01308 3.26e-88 - - - - - - - -
NLEFIACL_01309 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
NLEFIACL_01312 5.32e-12 - - - S - - - Short C-terminal domain
NLEFIACL_01313 4.59e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLEFIACL_01314 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLEFIACL_01315 1.02e-155 - - - S - - - repeat protein
NLEFIACL_01316 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
NLEFIACL_01317 0.0 - - - N - - - domain, Protein
NLEFIACL_01318 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
NLEFIACL_01319 5.92e-153 - - - N - - - WxL domain surface cell wall-binding
NLEFIACL_01320 9.37e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NLEFIACL_01321 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NLEFIACL_01322 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLEFIACL_01323 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NLEFIACL_01324 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NLEFIACL_01325 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLEFIACL_01326 7.74e-47 - - - - - - - -
NLEFIACL_01327 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NLEFIACL_01328 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLEFIACL_01329 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLEFIACL_01330 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NLEFIACL_01331 2.06e-187 ylmH - - S - - - S4 domain protein
NLEFIACL_01332 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NLEFIACL_01333 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLEFIACL_01334 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLEFIACL_01335 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLEFIACL_01336 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLEFIACL_01337 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLEFIACL_01338 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLEFIACL_01339 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLEFIACL_01340 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NLEFIACL_01341 7.01e-76 ftsL - - D - - - Cell division protein FtsL
NLEFIACL_01342 2.58e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLEFIACL_01343 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NLEFIACL_01344 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
NLEFIACL_01345 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NLEFIACL_01346 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NLEFIACL_01347 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLEFIACL_01348 1.76e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NLEFIACL_01349 8.82e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NLEFIACL_01351 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NLEFIACL_01352 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLEFIACL_01353 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
NLEFIACL_01354 1.55e-74 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NLEFIACL_01355 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NLEFIACL_01356 1.45e-149 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NLEFIACL_01357 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NLEFIACL_01358 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLEFIACL_01359 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NLEFIACL_01360 2.24e-148 yjbH - - Q - - - Thioredoxin
NLEFIACL_01361 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NLEFIACL_01362 7.52e-263 coiA - - S ko:K06198 - ko00000 Competence protein
NLEFIACL_01363 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NLEFIACL_01364 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLEFIACL_01365 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
NLEFIACL_01366 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NLEFIACL_01386 4.5e-94 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_01387 2.55e-58 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_01388 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NLEFIACL_01389 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NLEFIACL_01390 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLEFIACL_01391 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
NLEFIACL_01392 0.0 - - - M - - - domain protein
NLEFIACL_01393 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NLEFIACL_01394 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
NLEFIACL_01395 1.45e-46 - - - - - - - -
NLEFIACL_01396 2.83e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLEFIACL_01397 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLEFIACL_01398 4.54e-126 - - - J - - - glyoxalase III activity
NLEFIACL_01399 8.33e-189 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_01400 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
NLEFIACL_01401 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
NLEFIACL_01402 1.03e-212 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NLEFIACL_01403 3.05e-282 ysaA - - V - - - RDD family
NLEFIACL_01404 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
NLEFIACL_01405 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NLEFIACL_01406 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NLEFIACL_01407 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLEFIACL_01408 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NLEFIACL_01409 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLEFIACL_01410 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NLEFIACL_01411 1.05e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLEFIACL_01412 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLEFIACL_01413 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NLEFIACL_01414 1.34e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLEFIACL_01415 1.74e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLEFIACL_01416 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
NLEFIACL_01417 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NLEFIACL_01418 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLEFIACL_01419 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLEFIACL_01420 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLEFIACL_01421 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLEFIACL_01422 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLEFIACL_01423 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NLEFIACL_01424 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NLEFIACL_01425 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NLEFIACL_01426 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NLEFIACL_01427 1.12e-246 ampC - - V - - - Beta-lactamase
NLEFIACL_01428 8.57e-41 - - - - - - - -
NLEFIACL_01429 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NLEFIACL_01430 1.33e-77 - - - - - - - -
NLEFIACL_01431 5.37e-182 - - - - - - - -
NLEFIACL_01432 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NLEFIACL_01433 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01434 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
NLEFIACL_01435 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
NLEFIACL_01438 1.98e-40 - - - - - - - -
NLEFIACL_01441 7.78e-76 - - - - - - - -
NLEFIACL_01442 1.62e-53 - - - S - - - Phage gp6-like head-tail connector protein
NLEFIACL_01445 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NLEFIACL_01446 5.65e-256 - - - S - - - Phage portal protein
NLEFIACL_01447 2.13e-05 - - - - - - - -
NLEFIACL_01448 0.0 terL - - S - - - overlaps another CDS with the same product name
NLEFIACL_01449 2.22e-108 - - - L - - - overlaps another CDS with the same product name
NLEFIACL_01450 7.42e-89 - - - L - - - HNH endonuclease
NLEFIACL_01451 1.08e-64 - - - S - - - Head-tail joining protein
NLEFIACL_01453 2.76e-95 - - - - - - - -
NLEFIACL_01454 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NLEFIACL_01455 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NLEFIACL_01456 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLEFIACL_01457 1.04e-224 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLEFIACL_01458 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NLEFIACL_01459 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
NLEFIACL_01460 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NLEFIACL_01461 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLEFIACL_01462 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLEFIACL_01463 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NLEFIACL_01464 4.48e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NLEFIACL_01465 1.19e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NLEFIACL_01466 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NLEFIACL_01467 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NLEFIACL_01468 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NLEFIACL_01469 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLEFIACL_01470 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLEFIACL_01471 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLEFIACL_01472 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NLEFIACL_01473 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NLEFIACL_01474 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NLEFIACL_01475 7.67e-198 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NLEFIACL_01476 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NLEFIACL_01477 0.0 ydaO - - E - - - amino acid
NLEFIACL_01478 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLEFIACL_01479 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLEFIACL_01480 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_01481 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLEFIACL_01482 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NLEFIACL_01483 2.9e-255 glmS2 - - M - - - SIS domain
NLEFIACL_01484 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NLEFIACL_01485 5.51e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NLEFIACL_01486 4.21e-158 - - - S - - - YjbR
NLEFIACL_01488 0.0 cadA - - P - - - P-type ATPase
NLEFIACL_01489 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
NLEFIACL_01490 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NLEFIACL_01491 4.29e-101 - - - - - - - -
NLEFIACL_01492 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NLEFIACL_01493 1.32e-72 - - - FG - - - HIT domain
NLEFIACL_01494 1.66e-40 - - - FG - - - HIT domain
NLEFIACL_01495 1.05e-223 ydhF - - S - - - Aldo keto reductase
NLEFIACL_01496 8.93e-71 - - - S - - - Pfam:DUF59
NLEFIACL_01497 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLEFIACL_01498 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NLEFIACL_01499 1.87e-249 - - - V - - - Beta-lactamase
NLEFIACL_01500 3.74e-125 - - - V - - - VanZ like family
NLEFIACL_01501 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01502 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_01503 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NLEFIACL_01504 2.07e-302 - - - EK - - - Aminotransferase, class I
NLEFIACL_01505 3.36e-216 - - - K - - - LysR substrate binding domain
NLEFIACL_01506 2.21e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_01507 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NLEFIACL_01508 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NLEFIACL_01509 3.51e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NLEFIACL_01510 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NLEFIACL_01511 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NLEFIACL_01512 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NLEFIACL_01513 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NLEFIACL_01514 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLEFIACL_01515 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
NLEFIACL_01516 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLEFIACL_01517 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NLEFIACL_01518 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
NLEFIACL_01519 1.14e-159 vanR - - K - - - response regulator
NLEFIACL_01520 5.61e-273 hpk31 - - T - - - Histidine kinase
NLEFIACL_01521 1.26e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NLEFIACL_01522 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NLEFIACL_01523 2.05e-167 - - - E - - - branched-chain amino acid
NLEFIACL_01524 5.93e-73 - - - S - - - branched-chain amino acid
NLEFIACL_01525 4.79e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
NLEFIACL_01526 2.12e-72 - - - - - - - -
NLEFIACL_01527 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
NLEFIACL_01528 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
NLEFIACL_01529 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
NLEFIACL_01530 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
NLEFIACL_01531 2.73e-209 - - - - - - - -
NLEFIACL_01532 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NLEFIACL_01533 3.28e-147 - - - - - - - -
NLEFIACL_01534 1.26e-268 xylR - - GK - - - ROK family
NLEFIACL_01535 1.87e-232 ydbI - - K - - - AI-2E family transporter
NLEFIACL_01536 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLEFIACL_01537 6.79e-53 - - - - - - - -
NLEFIACL_01539 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
NLEFIACL_01540 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
NLEFIACL_01541 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_01542 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
NLEFIACL_01543 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NLEFIACL_01544 1.6e-103 - - - GM - - - SnoaL-like domain
NLEFIACL_01545 2.85e-141 - - - GM - - - NAD(P)H-binding
NLEFIACL_01546 4.71e-47 - - - S - - - aldo-keto reductase (NADP) activity
NLEFIACL_01547 2.31e-132 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NLEFIACL_01548 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
NLEFIACL_01549 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLEFIACL_01550 3.2e-109 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLEFIACL_01552 5.49e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NLEFIACL_01553 1.68e-121 - - - C - - - Alcohol dehydrogenase GroES-like domain
NLEFIACL_01554 8.95e-53 - - - C - - - Alcohol dehydrogenase GroES-like domain
NLEFIACL_01555 1.4e-57 - - - K - - - HxlR-like helix-turn-helix
NLEFIACL_01556 5.57e-141 yoaZ - - S - - - intracellular protease amidase
NLEFIACL_01557 7.29e-60 - - - S - - - Protein of unknown function (DUF3781)
NLEFIACL_01558 2.73e-284 - - - S - - - Membrane
NLEFIACL_01559 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_01560 4.34e-63 sgaB 2.7.1.194, 2.7.1.200 - G ko:K02774,ko:K02822,ko:K03475 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NLEFIACL_01561 1.43e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NLEFIACL_01562 0.0 - 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLEFIACL_01563 5.33e-86 - - - S - - - Protein of unknown function (DUF1093)
NLEFIACL_01564 0.0 - - - G ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757 ko00010,ko02060,map00010,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_01565 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_01566 6.07e-188 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NLEFIACL_01568 1.85e-41 - - - - - - - -
NLEFIACL_01569 1.11e-84 - - - - - - - -
NLEFIACL_01570 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
NLEFIACL_01571 1.04e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLEFIACL_01572 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NLEFIACL_01573 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
NLEFIACL_01574 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLEFIACL_01575 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
NLEFIACL_01576 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NLEFIACL_01577 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
NLEFIACL_01578 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NLEFIACL_01579 1.91e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLEFIACL_01580 1.82e-235 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NLEFIACL_01582 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
NLEFIACL_01583 8.36e-25 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
NLEFIACL_01584 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
NLEFIACL_01585 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NLEFIACL_01586 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NLEFIACL_01587 1.27e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NLEFIACL_01588 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLEFIACL_01589 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
NLEFIACL_01590 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NLEFIACL_01591 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
NLEFIACL_01592 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NLEFIACL_01593 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NLEFIACL_01594 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_01595 1.6e-96 - - - - - - - -
NLEFIACL_01596 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NLEFIACL_01597 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NLEFIACL_01598 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLEFIACL_01599 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLEFIACL_01600 7.94e-114 ykuL - - S - - - (CBS) domain
NLEFIACL_01601 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NLEFIACL_01602 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLEFIACL_01603 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NLEFIACL_01604 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
NLEFIACL_01605 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NLEFIACL_01606 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLEFIACL_01607 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLEFIACL_01608 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
NLEFIACL_01609 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLEFIACL_01610 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
NLEFIACL_01611 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLEFIACL_01612 1.86e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLEFIACL_01613 5.62e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NLEFIACL_01614 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLEFIACL_01615 1.03e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NLEFIACL_01616 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLEFIACL_01617 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLEFIACL_01618 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLEFIACL_01619 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLEFIACL_01620 2.07e-118 - - - - - - - -
NLEFIACL_01621 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NLEFIACL_01622 1.35e-93 - - - - - - - -
NLEFIACL_01623 1.2e-175 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NLEFIACL_01624 2.08e-125 - - - KT - - - response to antibiotic
NLEFIACL_01625 1.72e-69 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_01626 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
NLEFIACL_01627 2.48e-204 - - - S - - - Putative adhesin
NLEFIACL_01628 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_01629 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLEFIACL_01630 6.39e-234 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NLEFIACL_01631 1.07e-262 - - - S - - - DUF218 domain
NLEFIACL_01632 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NLEFIACL_01633 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01634 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLEFIACL_01635 6.26e-101 - - - - - - - -
NLEFIACL_01636 1.14e-195 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NLEFIACL_01637 1.44e-189 - - - S - - - haloacid dehalogenase-like hydrolase
NLEFIACL_01638 7.41e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NLEFIACL_01639 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
NLEFIACL_01640 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
NLEFIACL_01641 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_01642 1.03e-21 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
NLEFIACL_01643 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_01644 4.08e-101 - - - K - - - MerR family regulatory protein
NLEFIACL_01645 6.46e-201 - - - GM - - - NmrA-like family
NLEFIACL_01646 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_01647 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NLEFIACL_01649 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
NLEFIACL_01650 8.44e-304 - - - S - - - module of peptide synthetase
NLEFIACL_01651 3.32e-135 - - - - - - - -
NLEFIACL_01652 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NLEFIACL_01653 1.28e-77 - - - S - - - Enterocin A Immunity
NLEFIACL_01654 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
NLEFIACL_01655 1.6e-216 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NLEFIACL_01656 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
NLEFIACL_01657 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NLEFIACL_01658 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NLEFIACL_01659 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
NLEFIACL_01660 1.03e-34 - - - - - - - -
NLEFIACL_01661 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
NLEFIACL_01662 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
NLEFIACL_01663 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
NLEFIACL_01664 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
NLEFIACL_01665 1.67e-250 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NLEFIACL_01666 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NLEFIACL_01667 1.02e-72 - - - S - - - Enterocin A Immunity
NLEFIACL_01668 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLEFIACL_01669 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLEFIACL_01670 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLEFIACL_01671 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NLEFIACL_01672 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLEFIACL_01674 1.88e-106 - - - - - - - -
NLEFIACL_01675 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
NLEFIACL_01677 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NLEFIACL_01678 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLEFIACL_01679 1.54e-228 ydbI - - K - - - AI-2E family transporter
NLEFIACL_01680 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NLEFIACL_01681 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NLEFIACL_01682 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NLEFIACL_01683 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NLEFIACL_01684 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_01685 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NLEFIACL_01686 1.63e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_01688 2.77e-30 - - - - - - - -
NLEFIACL_01690 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NLEFIACL_01691 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NLEFIACL_01692 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NLEFIACL_01693 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NLEFIACL_01694 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NLEFIACL_01695 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NLEFIACL_01696 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLEFIACL_01697 4.26e-109 cvpA - - S - - - Colicin V production protein
NLEFIACL_01698 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NLEFIACL_01699 4.41e-316 - - - EGP - - - Major Facilitator
NLEFIACL_01701 4.54e-54 - - - - - - - -
NLEFIACL_01702 2.35e-52 - - - - - - - -
NLEFIACL_01703 2.59e-84 - - - - - - - -
NLEFIACL_01704 4.92e-90 - - - S - - - Immunity protein 63
NLEFIACL_01705 0.0 - - - S - - - Virulence-associated protein E
NLEFIACL_01706 3.96e-183 - - - L - - - DNA replication protein
NLEFIACL_01707 4.2e-37 - - - - - - - -
NLEFIACL_01709 2.12e-17 ansR - - K - - - Transcriptional regulator
NLEFIACL_01710 3.87e-284 - - - L - - - Belongs to the 'phage' integrase family
NLEFIACL_01711 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01712 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
NLEFIACL_01713 2.03e-84 - - - - - - - -
NLEFIACL_01714 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NLEFIACL_01715 1.21e-73 - - - - - - - -
NLEFIACL_01716 1.24e-194 - - - K - - - Helix-turn-helix domain
NLEFIACL_01717 2.75e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLEFIACL_01718 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_01719 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_01720 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_01721 1.57e-237 - - - GM - - - Male sterility protein
NLEFIACL_01722 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_01723 4.61e-101 - - - M - - - LysM domain
NLEFIACL_01724 1.44e-128 - - - M - - - Lysin motif
NLEFIACL_01725 9.47e-137 - - - S - - - SdpI/YhfL protein family
NLEFIACL_01726 1.58e-72 nudA - - S - - - ASCH
NLEFIACL_01727 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NLEFIACL_01728 2.06e-119 - - - - - - - -
NLEFIACL_01729 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
NLEFIACL_01730 3.55e-281 - - - T - - - diguanylate cyclase
NLEFIACL_01731 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
NLEFIACL_01732 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NLEFIACL_01733 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NLEFIACL_01734 3.05e-95 - - - - - - - -
NLEFIACL_01735 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_01736 1.08e-221 - - - C - - - C4-dicarboxylate transmembrane transporter activity
NLEFIACL_01737 2.15e-151 - - - GM - - - NAD(P)H-binding
NLEFIACL_01738 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NLEFIACL_01739 6.7e-102 yphH - - S - - - Cupin domain
NLEFIACL_01740 3.55e-79 - - - I - - - sulfurtransferase activity
NLEFIACL_01741 3.3e-87 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
NLEFIACL_01742 4.19e-70 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
NLEFIACL_01743 8.38e-152 - - - GM - - - NAD(P)H-binding
NLEFIACL_01744 2.31e-277 - - - - - - - -
NLEFIACL_01745 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_01746 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01747 1.3e-226 - - - O - - - protein import
NLEFIACL_01748 9.66e-292 amd - - E - - - Peptidase family M20/M25/M40
NLEFIACL_01749 2.43e-208 yhxD - - IQ - - - KR domain
NLEFIACL_01751 9.38e-91 - - - - - - - -
NLEFIACL_01752 1.74e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_01753 0.0 - - - E - - - Amino Acid
NLEFIACL_01754 1.67e-86 lysM - - M - - - LysM domain
NLEFIACL_01755 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NLEFIACL_01758 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
NLEFIACL_01759 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLEFIACL_01760 9.2e-62 - - - - - - - -
NLEFIACL_01761 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLEFIACL_01762 1.46e-239 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLEFIACL_01763 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
NLEFIACL_01764 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NLEFIACL_01765 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NLEFIACL_01766 8.88e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NLEFIACL_01767 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_01768 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NLEFIACL_01769 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01770 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NLEFIACL_01771 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
NLEFIACL_01772 1.22e-126 - - - C - - - Nitroreductase family
NLEFIACL_01773 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NLEFIACL_01774 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLEFIACL_01775 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_01776 1.22e-200 ccpB - - K - - - lacI family
NLEFIACL_01777 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
NLEFIACL_01778 1.18e-225 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NLEFIACL_01779 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NLEFIACL_01780 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
NLEFIACL_01781 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLEFIACL_01782 9.38e-139 pncA - - Q - - - Isochorismatase family
NLEFIACL_01783 2.66e-172 - - - - - - - -
NLEFIACL_01784 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_01785 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NLEFIACL_01786 7.2e-61 - - - S - - - Enterocin A Immunity
NLEFIACL_01787 2.29e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
NLEFIACL_01788 0.0 pepF2 - - E - - - Oligopeptidase F
NLEFIACL_01789 1.4e-95 - - - K - - - Transcriptional regulator
NLEFIACL_01790 1.86e-210 - - - - - - - -
NLEFIACL_01791 1.23e-75 - - - - - - - -
NLEFIACL_01792 4.83e-64 - - - - - - - -
NLEFIACL_01793 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
NLEFIACL_01794 0.0 nox - - C - - - NADH oxidase
NLEFIACL_01795 2.6e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NLEFIACL_01796 4.95e-310 - - - - - - - -
NLEFIACL_01797 6.83e-256 - - - S - - - Protein conserved in bacteria
NLEFIACL_01798 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
NLEFIACL_01799 0.0 - - - S - - - Bacterial cellulose synthase subunit
NLEFIACL_01800 7.91e-172 - - - T - - - diguanylate cyclase activity
NLEFIACL_01801 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLEFIACL_01802 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
NLEFIACL_01803 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
NLEFIACL_01804 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NLEFIACL_01805 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
NLEFIACL_01806 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLEFIACL_01807 4.63e-135 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NLEFIACL_01808 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NLEFIACL_01809 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NLEFIACL_01810 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLEFIACL_01811 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLEFIACL_01812 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLEFIACL_01813 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLEFIACL_01814 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NLEFIACL_01815 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
NLEFIACL_01816 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NLEFIACL_01817 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NLEFIACL_01818 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NLEFIACL_01819 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_01820 8.95e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLEFIACL_01821 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLEFIACL_01823 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NLEFIACL_01824 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NLEFIACL_01825 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLEFIACL_01826 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NLEFIACL_01827 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLEFIACL_01828 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLEFIACL_01829 5.11e-171 - - - - - - - -
NLEFIACL_01830 0.0 eriC - - P ko:K03281 - ko00000 chloride
NLEFIACL_01831 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NLEFIACL_01832 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NLEFIACL_01833 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLEFIACL_01834 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLEFIACL_01835 0.0 - - - M - - - Domain of unknown function (DUF5011)
NLEFIACL_01836 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_01837 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01838 7.98e-137 - - - - - - - -
NLEFIACL_01839 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_01840 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLEFIACL_01841 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NLEFIACL_01842 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NLEFIACL_01843 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
NLEFIACL_01844 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NLEFIACL_01845 1.46e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NLEFIACL_01846 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NLEFIACL_01847 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NLEFIACL_01848 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NLEFIACL_01849 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_01850 2.7e-154 - - - S - - - Protein of unknown function (DUF1361)
NLEFIACL_01851 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLEFIACL_01852 1.03e-180 ybbR - - S - - - YbbR-like protein
NLEFIACL_01853 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLEFIACL_01854 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLEFIACL_01855 3.15e-158 - - - T - - - EAL domain
NLEFIACL_01856 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_01857 7.01e-135 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_01858 1.7e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NLEFIACL_01859 3.38e-70 - - - - - - - -
NLEFIACL_01860 2.05e-94 - - - - - - - -
NLEFIACL_01861 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NLEFIACL_01862 7.34e-180 - - - EGP - - - Transmembrane secretion effector
NLEFIACL_01863 1.15e-41 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NLEFIACL_01864 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLEFIACL_01865 4.13e-182 - - - - - - - -
NLEFIACL_01867 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
NLEFIACL_01868 3.88e-46 - - - - - - - -
NLEFIACL_01869 2.08e-117 - - - V - - - VanZ like family
NLEFIACL_01870 1.06e-314 - - - EGP - - - Major Facilitator
NLEFIACL_01871 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NLEFIACL_01872 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NLEFIACL_01873 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NLEFIACL_01874 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
NLEFIACL_01875 6.16e-107 - - - K - - - Transcriptional regulator
NLEFIACL_01876 1.36e-27 - - - - - - - -
NLEFIACL_01877 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NLEFIACL_01878 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NLEFIACL_01879 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NLEFIACL_01880 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NLEFIACL_01881 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NLEFIACL_01882 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLEFIACL_01883 0.0 oatA - - I - - - Acyltransferase
NLEFIACL_01884 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLEFIACL_01885 1.89e-90 - - - O - - - OsmC-like protein
NLEFIACL_01886 1.09e-60 - - - - - - - -
NLEFIACL_01887 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NLEFIACL_01888 6.12e-115 - - - - - - - -
NLEFIACL_01889 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NLEFIACL_01890 3.05e-95 - - - F - - - Nudix hydrolase
NLEFIACL_01891 1.48e-27 - - - - - - - -
NLEFIACL_01892 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NLEFIACL_01893 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NLEFIACL_01894 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NLEFIACL_01895 1.44e-188 - - - - - - - -
NLEFIACL_01897 2.83e-145 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
NLEFIACL_01898 3.08e-266 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NLEFIACL_01899 5.1e-218 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLEFIACL_01900 1.28e-54 - - - - - - - -
NLEFIACL_01901 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_01902 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NLEFIACL_01903 1.81e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_01904 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_01905 1e-107 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLEFIACL_01906 1.57e-196 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NLEFIACL_01907 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLEFIACL_01908 1.24e-179 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
NLEFIACL_01909 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
NLEFIACL_01910 2.55e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_01911 1.79e-190 - - - S - - - Sulfite exporter TauE/SafE
NLEFIACL_01912 3.08e-93 - - - K - - - MarR family
NLEFIACL_01913 6.5e-269 - - - EGP - - - Major Facilitator Superfamily
NLEFIACL_01914 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
NLEFIACL_01915 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_01916 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLEFIACL_01917 1.88e-101 rppH3 - - F - - - NUDIX domain
NLEFIACL_01918 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NLEFIACL_01919 1.61e-36 - - - - - - - -
NLEFIACL_01920 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
NLEFIACL_01921 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
NLEFIACL_01922 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NLEFIACL_01923 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NLEFIACL_01924 2.84e-146 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NLEFIACL_01925 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NLEFIACL_01926 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NLEFIACL_01927 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NLEFIACL_01928 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NLEFIACL_01930 3.56e-171 spoVK - - O ko:K06413 - ko00000 ATPase family associated with various cellular activities (AAA)
NLEFIACL_01932 3.07e-59 - - - L - - - Helix-turn-helix domain
NLEFIACL_01933 1.51e-22 - - - L ko:K07497 - ko00000 hmm pf00665
NLEFIACL_01934 1.37e-37 - - - L ko:K07497 - ko00000 hmm pf00665
NLEFIACL_01935 6.67e-30 - - - L ko:K07497 - ko00000 hmm pf00665
NLEFIACL_01936 4.16e-97 - - - - - - - -
NLEFIACL_01937 1.08e-71 - - - - - - - -
NLEFIACL_01938 1.37e-83 - - - K - - - Helix-turn-helix domain
NLEFIACL_01939 1.16e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_01940 3.08e-74 - - - K - - - HxlR-like helix-turn-helix
NLEFIACL_01941 1.92e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NLEFIACL_01942 3.5e-299 - - - S - - - Cysteine-rich secretory protein family
NLEFIACL_01943 3.61e-61 - - - S - - - MORN repeat
NLEFIACL_01944 0.0 XK27_09800 - - I - - - Acyltransferase family
NLEFIACL_01945 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
NLEFIACL_01946 1.95e-116 - - - - - - - -
NLEFIACL_01947 5.74e-32 - - - - - - - -
NLEFIACL_01948 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
NLEFIACL_01949 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
NLEFIACL_01950 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
NLEFIACL_01951 4.25e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
NLEFIACL_01952 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NLEFIACL_01953 2.19e-131 - - - G - - - Glycogen debranching enzyme
NLEFIACL_01954 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NLEFIACL_01955 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NLEFIACL_01956 3.37e-60 - - - S - - - MazG-like family
NLEFIACL_01957 2.31e-117 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NLEFIACL_01958 0.0 - - - M - - - MucBP domain
NLEFIACL_01959 1.42e-08 - - - - - - - -
NLEFIACL_01960 4.17e-95 - - - S - - - AAA domain
NLEFIACL_01961 1.06e-179 - - - K - - - sequence-specific DNA binding
NLEFIACL_01962 1.88e-124 - - - K - - - Helix-turn-helix domain
NLEFIACL_01963 1.37e-220 - - - K - - - Transcriptional regulator
NLEFIACL_01964 0.0 - - - C - - - FMN_bind
NLEFIACL_01966 4.3e-106 - - - K - - - Transcriptional regulator
NLEFIACL_01967 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLEFIACL_01968 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NLEFIACL_01969 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NLEFIACL_01970 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NLEFIACL_01971 3.79e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NLEFIACL_01972 5.44e-56 - - - - - - - -
NLEFIACL_01973 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
NLEFIACL_01974 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NLEFIACL_01975 1.36e-208 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NLEFIACL_01976 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_01977 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
NLEFIACL_01978 1.12e-243 - - - - - - - -
NLEFIACL_01979 3.28e-278 yibE - - S - - - overlaps another CDS with the same product name
NLEFIACL_01980 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
NLEFIACL_01981 1.31e-129 - - - K - - - FR47-like protein
NLEFIACL_01982 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
NLEFIACL_01983 3.33e-64 - - - - - - - -
NLEFIACL_01984 7.32e-247 - - - I - - - alpha/beta hydrolase fold
NLEFIACL_01985 0.0 xylP2 - - G - - - symporter
NLEFIACL_01986 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLEFIACL_01987 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NLEFIACL_01988 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NLEFIACL_01989 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NLEFIACL_01990 1.43e-155 azlC - - E - - - branched-chain amino acid
NLEFIACL_01991 1.75e-47 - - - K - - - MerR HTH family regulatory protein
NLEFIACL_01992 4.97e-96 cpsE - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NLEFIACL_01993 1.87e-48 - - - L - - - recombinase activity
NLEFIACL_01994 1.18e-59 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NLEFIACL_01995 4.04e-62 - - - M - - - domain protein
NLEFIACL_01996 3.33e-27 - - - M - - - domain protein
NLEFIACL_01998 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NLEFIACL_01999 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NLEFIACL_02000 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLEFIACL_02001 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLEFIACL_02002 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLEFIACL_02003 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLEFIACL_02004 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLEFIACL_02005 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLEFIACL_02006 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NLEFIACL_02007 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLEFIACL_02008 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NLEFIACL_02009 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NLEFIACL_02010 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NLEFIACL_02011 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
NLEFIACL_02012 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NLEFIACL_02013 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NLEFIACL_02014 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLEFIACL_02015 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02016 1.23e-190 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NLEFIACL_02017 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NLEFIACL_02018 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
NLEFIACL_02019 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NLEFIACL_02020 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NLEFIACL_02021 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NLEFIACL_02022 1.81e-99 - - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_02023 3.65e-70 - - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_02024 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NLEFIACL_02025 2.37e-107 uspA - - T - - - universal stress protein
NLEFIACL_02026 1.34e-52 - - - - - - - -
NLEFIACL_02027 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NLEFIACL_02028 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NLEFIACL_02029 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
NLEFIACL_02030 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NLEFIACL_02031 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NLEFIACL_02032 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NLEFIACL_02033 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NLEFIACL_02034 3.95e-288 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NLEFIACL_02035 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_02036 6.4e-142 - - - S - - - Protein of unknown function (DUF1648)
NLEFIACL_02037 2.82e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NLEFIACL_02038 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
NLEFIACL_02039 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLEFIACL_02040 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NLEFIACL_02041 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLEFIACL_02042 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NLEFIACL_02043 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLEFIACL_02044 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NLEFIACL_02045 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLEFIACL_02046 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLEFIACL_02047 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NLEFIACL_02048 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
NLEFIACL_02049 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NLEFIACL_02050 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NLEFIACL_02051 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NLEFIACL_02052 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NLEFIACL_02053 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NLEFIACL_02054 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NLEFIACL_02055 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02056 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NLEFIACL_02057 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NLEFIACL_02058 3.55e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
NLEFIACL_02059 0.0 ymfH - - S - - - Peptidase M16
NLEFIACL_02060 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NLEFIACL_02061 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLEFIACL_02062 2.21e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NLEFIACL_02063 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLEFIACL_02064 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NLEFIACL_02065 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
NLEFIACL_02066 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLEFIACL_02067 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLEFIACL_02068 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NLEFIACL_02069 2.01e-141 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NLEFIACL_02070 4.45e-99 - - - K - - - Transcriptional regulator
NLEFIACL_02071 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NLEFIACL_02072 3.73e-104 - - - S - - - Protein of unknown function (DUF3021)
NLEFIACL_02073 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NLEFIACL_02074 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_02075 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NLEFIACL_02077 2.52e-203 morA - - S - - - reductase
NLEFIACL_02078 6.75e-212 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
NLEFIACL_02079 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
NLEFIACL_02080 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NLEFIACL_02081 4.03e-132 - - - - - - - -
NLEFIACL_02082 0.0 - - - - - - - -
NLEFIACL_02083 6.49e-268 - - - C - - - Oxidoreductase
NLEFIACL_02084 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NLEFIACL_02085 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02086 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NLEFIACL_02087 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NLEFIACL_02088 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
NLEFIACL_02089 7.71e-183 - - - - - - - -
NLEFIACL_02090 3.16e-191 - - - - - - - -
NLEFIACL_02091 3.37e-115 - - - - - - - -
NLEFIACL_02092 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NLEFIACL_02093 1.04e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_02094 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NLEFIACL_02095 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02096 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
NLEFIACL_02097 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
NLEFIACL_02099 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_02100 1.93e-242 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NLEFIACL_02101 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NLEFIACL_02102 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NLEFIACL_02103 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NLEFIACL_02104 8.08e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_02105 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NLEFIACL_02106 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
NLEFIACL_02107 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NLEFIACL_02108 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLEFIACL_02109 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_02110 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02111 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
NLEFIACL_02112 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
NLEFIACL_02113 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NLEFIACL_02114 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NLEFIACL_02115 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
NLEFIACL_02116 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NLEFIACL_02117 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NLEFIACL_02118 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_02119 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NLEFIACL_02120 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NLEFIACL_02121 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLEFIACL_02122 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NLEFIACL_02123 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NLEFIACL_02124 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLEFIACL_02125 5.99e-213 mleR - - K - - - LysR substrate binding domain
NLEFIACL_02126 0.0 - - - M - - - domain protein
NLEFIACL_02128 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NLEFIACL_02129 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_02130 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_02131 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NLEFIACL_02132 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLEFIACL_02133 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLEFIACL_02134 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
NLEFIACL_02135 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NLEFIACL_02136 6.33e-46 - - - - - - - -
NLEFIACL_02137 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
NLEFIACL_02138 8.83e-208 fbpA - - K - - - Domain of unknown function (DUF814)
NLEFIACL_02139 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLEFIACL_02140 3.81e-18 - - - - - - - -
NLEFIACL_02141 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLEFIACL_02142 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLEFIACL_02143 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
NLEFIACL_02145 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NLEFIACL_02146 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLEFIACL_02147 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
NLEFIACL_02148 5.84e-115 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NLEFIACL_02149 2.16e-201 dkgB - - S - - - reductase
NLEFIACL_02150 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLEFIACL_02151 1.57e-89 - - - - - - - -
NLEFIACL_02152 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
NLEFIACL_02153 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLEFIACL_02154 2.22e-221 - - - P - - - Major Facilitator Superfamily
NLEFIACL_02155 7.88e-283 - - - C - - - FAD dependent oxidoreductase
NLEFIACL_02156 7.02e-126 - - - K - - - Helix-turn-helix domain
NLEFIACL_02157 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NLEFIACL_02158 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_02159 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NLEFIACL_02160 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02161 2.15e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NLEFIACL_02162 1.21e-111 - - - - - - - -
NLEFIACL_02163 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NLEFIACL_02164 3.43e-66 - - - - - - - -
NLEFIACL_02165 1.22e-125 - - - - - - - -
NLEFIACL_02166 2.98e-90 - - - - - - - -
NLEFIACL_02167 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NLEFIACL_02168 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NLEFIACL_02169 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NLEFIACL_02170 4.3e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NLEFIACL_02171 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NLEFIACL_02172 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NLEFIACL_02173 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NLEFIACL_02174 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NLEFIACL_02175 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
NLEFIACL_02176 2.21e-56 - - - - - - - -
NLEFIACL_02177 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NLEFIACL_02178 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLEFIACL_02179 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_02180 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLEFIACL_02181 2.6e-185 - - - - - - - -
NLEFIACL_02182 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NLEFIACL_02183 3.2e-91 - - - - - - - -
NLEFIACL_02184 8.9e-96 ywnA - - K - - - Transcriptional regulator
NLEFIACL_02185 1.05e-155 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_02186 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NLEFIACL_02187 1.15e-152 - - - - - - - -
NLEFIACL_02188 2.92e-57 - - - - - - - -
NLEFIACL_02189 1.55e-55 - - - - - - - -
NLEFIACL_02190 0.0 ydiC - - EGP - - - Major Facilitator
NLEFIACL_02191 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_02192 9.08e-317 hpk2 - - T - - - Histidine kinase
NLEFIACL_02193 1.1e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
NLEFIACL_02194 2.42e-65 - - - - - - - -
NLEFIACL_02195 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
NLEFIACL_02196 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02197 3.35e-75 - - - - - - - -
NLEFIACL_02198 2.87e-56 - - - - - - - -
NLEFIACL_02199 2.92e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NLEFIACL_02200 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NLEFIACL_02201 1.49e-63 - - - - - - - -
NLEFIACL_02202 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NLEFIACL_02203 6.79e-135 - - - K - - - transcriptional regulator
NLEFIACL_02204 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NLEFIACL_02205 1.96e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NLEFIACL_02206 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NLEFIACL_02207 5.88e-285 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NLEFIACL_02208 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_02209 9.28e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02210 2.63e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02211 7.98e-80 - - - M - - - Lysin motif
NLEFIACL_02212 1.31e-97 - - - M - - - LysM domain protein
NLEFIACL_02213 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
NLEFIACL_02214 9.03e-229 - - - - - - - -
NLEFIACL_02215 6.88e-170 - - - - - - - -
NLEFIACL_02216 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NLEFIACL_02217 2.03e-75 - - - - - - - -
NLEFIACL_02218 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLEFIACL_02219 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
NLEFIACL_02220 1.24e-99 - - - K - - - Transcriptional regulator
NLEFIACL_02221 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NLEFIACL_02222 9.97e-50 - - - - - - - -
NLEFIACL_02224 1.04e-35 - - - - - - - -
NLEFIACL_02225 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
NLEFIACL_02226 7.53e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_02227 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02228 9e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02229 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLEFIACL_02230 6.1e-124 - - - K - - - Cupin domain
NLEFIACL_02231 8.08e-110 - - - S - - - ASCH
NLEFIACL_02232 1.88e-111 - - - K - - - GNAT family
NLEFIACL_02233 1.24e-116 - - - K - - - acetyltransferase
NLEFIACL_02234 2.06e-30 - - - - - - - -
NLEFIACL_02235 4.16e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NLEFIACL_02236 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_02237 1.08e-243 - - - - - - - -
NLEFIACL_02238 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
NLEFIACL_02239 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NLEFIACL_02241 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
NLEFIACL_02242 4.09e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NLEFIACL_02243 3.48e-40 - - - - - - - -
NLEFIACL_02244 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NLEFIACL_02245 6.4e-54 - - - - - - - -
NLEFIACL_02246 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NLEFIACL_02247 2.03e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLEFIACL_02248 1.45e-79 - - - S - - - CHY zinc finger
NLEFIACL_02249 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NLEFIACL_02250 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLEFIACL_02251 5.18e-115 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_02252 5.67e-187 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLEFIACL_02253 6.46e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NLEFIACL_02254 1.1e-280 - - - - - - - -
NLEFIACL_02255 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NLEFIACL_02256 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLEFIACL_02257 2.76e-59 - - - - - - - -
NLEFIACL_02258 1.18e-121 - - - K - - - Transcriptional regulator PadR-like family
NLEFIACL_02259 0.0 - - - P - - - Major Facilitator Superfamily
NLEFIACL_02260 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NLEFIACL_02261 3.66e-226 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NLEFIACL_02262 8.95e-60 - - - - - - - -
NLEFIACL_02263 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
NLEFIACL_02264 1.19e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NLEFIACL_02265 0.0 sufI - - Q - - - Multicopper oxidase
NLEFIACL_02266 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NLEFIACL_02267 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NLEFIACL_02268 3.25e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NLEFIACL_02269 8.37e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NLEFIACL_02270 2.16e-103 - - - - - - - -
NLEFIACL_02271 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLEFIACL_02272 4.27e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NLEFIACL_02273 2.82e-206 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_02274 1.17e-101 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
NLEFIACL_02275 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NLEFIACL_02276 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02277 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NLEFIACL_02278 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLEFIACL_02279 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NLEFIACL_02280 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_02281 0.0 - - - M - - - domain protein
NLEFIACL_02282 6.26e-75 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
NLEFIACL_02283 2.9e-225 - - - - - - - -
NLEFIACL_02284 6.97e-45 - - - - - - - -
NLEFIACL_02285 3.22e-213 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NLEFIACL_02286 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NLEFIACL_02287 2.38e-99 - - - - - - - -
NLEFIACL_02288 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NLEFIACL_02289 4.85e-180 - - - - - - - -
NLEFIACL_02290 4.07e-05 - - - - - - - -
NLEFIACL_02291 2.17e-141 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NLEFIACL_02292 1.67e-54 - - - - - - - -
NLEFIACL_02293 5.84e-164 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_02294 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NLEFIACL_02295 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NLEFIACL_02296 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
NLEFIACL_02297 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
NLEFIACL_02298 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
NLEFIACL_02299 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NLEFIACL_02300 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
NLEFIACL_02301 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_02302 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
NLEFIACL_02303 1.04e-79 - - - C - - - Zinc-binding dehydrogenase
NLEFIACL_02304 9.36e-120 - - - C - - - Zinc-binding dehydrogenase
NLEFIACL_02305 3.77e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NLEFIACL_02306 3.03e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NLEFIACL_02307 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NLEFIACL_02308 1.97e-259 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NLEFIACL_02309 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NLEFIACL_02310 0.0 - - - L - - - HIRAN domain
NLEFIACL_02311 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NLEFIACL_02312 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NLEFIACL_02313 1e-156 - - - - - - - -
NLEFIACL_02314 2.94e-191 - - - I - - - Alpha/beta hydrolase family
NLEFIACL_02315 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NLEFIACL_02316 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLEFIACL_02317 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLEFIACL_02318 1.84e-189 - - - - - - - -
NLEFIACL_02319 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NLEFIACL_02320 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
NLEFIACL_02321 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NLEFIACL_02322 1.49e-273 - - - J - - - translation release factor activity
NLEFIACL_02323 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NLEFIACL_02324 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NLEFIACL_02325 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLEFIACL_02326 2.41e-37 - - - - - - - -
NLEFIACL_02327 1.89e-169 - - - S - - - YheO-like PAS domain
NLEFIACL_02328 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NLEFIACL_02329 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NLEFIACL_02330 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
NLEFIACL_02331 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLEFIACL_02332 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLEFIACL_02333 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLEFIACL_02334 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
NLEFIACL_02335 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NLEFIACL_02336 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NLEFIACL_02337 4.15e-191 yxeH - - S - - - hydrolase
NLEFIACL_02338 7.12e-178 - - - - - - - -
NLEFIACL_02339 1.15e-235 - - - S - - - DUF218 domain
NLEFIACL_02340 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLEFIACL_02341 1.1e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NLEFIACL_02342 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLEFIACL_02343 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NLEFIACL_02344 5.3e-49 - - - - - - - -
NLEFIACL_02345 2.4e-56 - - - S - - - ankyrin repeats
NLEFIACL_02346 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NLEFIACL_02347 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLEFIACL_02348 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
NLEFIACL_02349 1.86e-208 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLEFIACL_02350 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
NLEFIACL_02351 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLEFIACL_02352 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLEFIACL_02353 6.64e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NLEFIACL_02354 1.17e-269 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
NLEFIACL_02355 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLEFIACL_02356 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
NLEFIACL_02357 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
NLEFIACL_02358 8.73e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NLEFIACL_02359 4.65e-229 - - - - - - - -
NLEFIACL_02360 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NLEFIACL_02361 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NLEFIACL_02362 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
NLEFIACL_02363 4.99e-262 - - - - - - - -
NLEFIACL_02364 2.94e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLEFIACL_02365 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
NLEFIACL_02366 6.97e-209 - - - GK - - - ROK family
NLEFIACL_02367 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_02368 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02369 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
NLEFIACL_02370 9.68e-34 - - - - - - - -
NLEFIACL_02371 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02372 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
NLEFIACL_02373 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NLEFIACL_02374 1.38e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NLEFIACL_02375 0.0 - - - L - - - DNA helicase
NLEFIACL_02376 1.85e-40 - - - - - - - -
NLEFIACL_02377 3.34e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02378 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02379 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02380 3.26e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02381 1.49e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NLEFIACL_02382 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLEFIACL_02383 8.82e-32 - - - - - - - -
NLEFIACL_02384 1.93e-31 plnF - - - - - - -
NLEFIACL_02385 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02386 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NLEFIACL_02387 2.48e-172 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NLEFIACL_02388 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NLEFIACL_02389 1.9e-25 plnA - - - - - - -
NLEFIACL_02390 1.22e-36 - - - - - - - -
NLEFIACL_02391 2.08e-160 plnP - - S - - - CAAX protease self-immunity
NLEFIACL_02392 5.58e-291 - - - M - - - Glycosyl transferase family 2
NLEFIACL_02394 4.08e-39 - - - - - - - -
NLEFIACL_02395 8.53e-34 plnJ - - - - - - -
NLEFIACL_02396 3.29e-32 plnK - - - - - - -
NLEFIACL_02397 9.76e-153 - - - - - - - -
NLEFIACL_02398 6.24e-25 plnR - - - - - - -
NLEFIACL_02399 1.15e-43 - - - - - - - -
NLEFIACL_02401 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLEFIACL_02402 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NLEFIACL_02403 8.38e-192 - - - S - - - hydrolase
NLEFIACL_02404 2.35e-212 - - - K - - - Transcriptional regulator
NLEFIACL_02405 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_02406 7.81e-263 - - - EGP - - - Transporter, major facilitator family protein
NLEFIACL_02407 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLEFIACL_02408 5.32e-51 - - - - - - - -
NLEFIACL_02409 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NLEFIACL_02410 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_02411 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
NLEFIACL_02412 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
NLEFIACL_02413 1.01e-26 - - - - - - - -
NLEFIACL_02414 7.94e-124 dpsB - - P - - - Belongs to the Dps family
NLEFIACL_02415 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
NLEFIACL_02416 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NLEFIACL_02417 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NLEFIACL_02418 2.45e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02419 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NLEFIACL_02420 3.63e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_02421 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NLEFIACL_02422 7.92e-99 yphH - - S - - - Cupin domain
NLEFIACL_02423 7.37e-103 - - - K - - - transcriptional regulator, MerR family
NLEFIACL_02424 2.1e-19 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NLEFIACL_02425 1.7e-246 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NLEFIACL_02426 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NLEFIACL_02427 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02429 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLEFIACL_02430 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLEFIACL_02431 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NLEFIACL_02432 2.82e-110 - - - - - - - -
NLEFIACL_02433 5.14e-111 yvbK - - K - - - GNAT family
NLEFIACL_02434 2.8e-49 - - - - - - - -
NLEFIACL_02435 2.81e-64 - - - - - - - -
NLEFIACL_02436 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
NLEFIACL_02437 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
NLEFIACL_02438 1.57e-202 - - - K - - - LysR substrate binding domain
NLEFIACL_02439 2.53e-134 - - - GM - - - NAD(P)H-binding
NLEFIACL_02440 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NLEFIACL_02441 5.85e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NLEFIACL_02442 1.2e-181 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NLEFIACL_02443 5.63e-104 - - - S - - - Protein of unknown function (DUF1211)
NLEFIACL_02444 2.14e-98 - - - C - - - Flavodoxin
NLEFIACL_02445 2.78e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
NLEFIACL_02446 1.43e-114 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NLEFIACL_02447 7.8e-113 - - - GM - - - NAD(P)H-binding
NLEFIACL_02448 2.11e-132 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NLEFIACL_02449 5.63e-98 - - - K - - - Transcriptional regulator
NLEFIACL_02451 3.64e-32 - - - C - - - Flavodoxin
NLEFIACL_02452 1.69e-08 adhR - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_02453 8.2e-146 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NLEFIACL_02454 2.41e-165 - - - C - - - Aldo keto reductase
NLEFIACL_02455 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NLEFIACL_02456 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NLEFIACL_02457 5.55e-106 - - - GM - - - NAD(P)H-binding
NLEFIACL_02458 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
NLEFIACL_02459 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NLEFIACL_02460 1.19e-160 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NLEFIACL_02461 1.12e-105 - - - - - - - -
NLEFIACL_02462 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NLEFIACL_02463 3.45e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NLEFIACL_02464 1.52e-131 - - - M - - - Protein of unknown function (DUF3737)
NLEFIACL_02465 4.96e-247 - - - C - - - Aldo/keto reductase family
NLEFIACL_02467 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_02468 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLEFIACL_02469 1.95e-89 - - - EGP - - - Major Facilitator
NLEFIACL_02470 2.68e-144 - - - EGP - - - Major Facilitator
NLEFIACL_02473 1.58e-230 yhgE - - V ko:K01421 - ko00000 domain protein
NLEFIACL_02474 1.74e-123 - - - K - - - Transcriptional regulator (TetR family)
NLEFIACL_02475 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_02476 3.34e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NLEFIACL_02477 1.06e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NLEFIACL_02478 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NLEFIACL_02479 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02480 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NLEFIACL_02481 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NLEFIACL_02482 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NLEFIACL_02483 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NLEFIACL_02484 2.33e-265 - - - EGP - - - Major facilitator Superfamily
NLEFIACL_02485 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
NLEFIACL_02486 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NLEFIACL_02487 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NLEFIACL_02488 2.85e-206 - - - I - - - alpha/beta hydrolase fold
NLEFIACL_02489 1.01e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NLEFIACL_02490 0.0 - - - - - - - -
NLEFIACL_02491 2e-52 - - - S - - - Cytochrome B5
NLEFIACL_02492 3.54e-117 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLEFIACL_02493 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
NLEFIACL_02494 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
NLEFIACL_02495 8.59e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLEFIACL_02496 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NLEFIACL_02497 1.56e-108 - - - - - - - -
NLEFIACL_02498 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLEFIACL_02499 1.59e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLEFIACL_02500 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLEFIACL_02501 3.7e-30 - - - - - - - -
NLEFIACL_02502 1.84e-134 - - - - - - - -
NLEFIACL_02503 5.12e-212 - - - K - - - LysR substrate binding domain
NLEFIACL_02504 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
NLEFIACL_02505 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NLEFIACL_02506 1.71e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NLEFIACL_02507 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_02508 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NLEFIACL_02509 1.4e-162 - - - S - - - DJ-1/PfpI family
NLEFIACL_02510 7.65e-121 yfbM - - K - - - FR47-like protein
NLEFIACL_02511 4.28e-195 - - - EG - - - EamA-like transporter family
NLEFIACL_02512 1.9e-79 - - - S - - - Protein of unknown function
NLEFIACL_02513 7.44e-51 - - - S - - - Protein of unknown function
NLEFIACL_02514 0.0 fusA1 - - J - - - elongation factor G
NLEFIACL_02515 1.34e-151 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLEFIACL_02516 1.67e-220 - - - K - - - WYL domain
NLEFIACL_02517 3.06e-165 - - - F - - - glutamine amidotransferase
NLEFIACL_02518 1.65e-106 - - - S - - - ASCH
NLEFIACL_02519 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
NLEFIACL_02520 3.97e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NLEFIACL_02521 0.0 - - - S - - - Putative threonine/serine exporter
NLEFIACL_02522 2.95e-125 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLEFIACL_02523 4.47e-73 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLEFIACL_02524 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NLEFIACL_02525 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
NLEFIACL_02526 5.07e-157 ydgI - - C - - - Nitroreductase family
NLEFIACL_02527 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NLEFIACL_02528 4.06e-211 - - - S - - - KR domain
NLEFIACL_02529 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLEFIACL_02530 2.49e-95 - - - C - - - FMN binding
NLEFIACL_02531 1.46e-204 - - - K - - - LysR family
NLEFIACL_02532 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NLEFIACL_02533 0.0 - - - C - - - FMN_bind
NLEFIACL_02534 5.25e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
NLEFIACL_02535 2.02e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NLEFIACL_02536 2.24e-155 pnb - - C - - - nitroreductase
NLEFIACL_02537 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
NLEFIACL_02538 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
NLEFIACL_02539 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
NLEFIACL_02540 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLEFIACL_02541 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NLEFIACL_02542 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NLEFIACL_02543 3.54e-195 yycI - - S - - - YycH protein
NLEFIACL_02544 5.04e-313 yycH - - S - - - YycH protein
NLEFIACL_02545 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NLEFIACL_02546 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NLEFIACL_02548 2.54e-50 - - - - - - - -
NLEFIACL_02549 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
NLEFIACL_02550 5.33e-103 - - - S - - - Pyridoxamine 5'-phosphate oxidase
NLEFIACL_02551 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
NLEFIACL_02552 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NLEFIACL_02553 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
NLEFIACL_02555 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NLEFIACL_02556 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLEFIACL_02557 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NLEFIACL_02558 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NLEFIACL_02559 2.98e-269 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLEFIACL_02560 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLEFIACL_02562 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_02564 9.32e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLEFIACL_02565 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLEFIACL_02566 4.96e-289 yttB - - EGP - - - Major Facilitator
NLEFIACL_02567 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NLEFIACL_02568 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NLEFIACL_02569 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NLEFIACL_02570 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLEFIACL_02571 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLEFIACL_02572 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NLEFIACL_02573 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLEFIACL_02574 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLEFIACL_02575 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLEFIACL_02576 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NLEFIACL_02577 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLEFIACL_02578 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLEFIACL_02579 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLEFIACL_02580 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLEFIACL_02581 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_02582 2.64e-305 - - - Q - - - Imidazolonepropionase and related amidohydrolases
NLEFIACL_02583 5.56e-172 jag - - S ko:K06346 - ko00000 R3H domain protein
NLEFIACL_02584 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLEFIACL_02585 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLEFIACL_02586 1.31e-143 - - - S - - - Cell surface protein
NLEFIACL_02587 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
NLEFIACL_02589 0.0 - - - - - - - -
NLEFIACL_02590 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NLEFIACL_02592 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NLEFIACL_02593 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NLEFIACL_02594 4.02e-203 degV1 - - S - - - DegV family
NLEFIACL_02595 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
NLEFIACL_02596 3.79e-181 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NLEFIACL_02597 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NLEFIACL_02598 7.43e-130 padR - - K - - - Virulence activator alpha C-term
NLEFIACL_02599 2.51e-103 - - - T - - - Universal stress protein family
NLEFIACL_02600 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NLEFIACL_02601 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLEFIACL_02602 3.87e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLEFIACL_02603 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NLEFIACL_02604 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
NLEFIACL_02605 3.14e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NLEFIACL_02606 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NLEFIACL_02607 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NLEFIACL_02608 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NLEFIACL_02609 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NLEFIACL_02610 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NLEFIACL_02611 1.9e-85 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
NLEFIACL_02612 4.67e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NLEFIACL_02613 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NLEFIACL_02614 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NLEFIACL_02615 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NLEFIACL_02616 3.09e-209 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NLEFIACL_02617 1.45e-162 - - - S - - - Membrane
NLEFIACL_02618 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
NLEFIACL_02619 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NLEFIACL_02620 5.03e-95 - - - K - - - Transcriptional regulator
NLEFIACL_02621 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NLEFIACL_02622 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NLEFIACL_02624 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NLEFIACL_02625 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NLEFIACL_02626 9.62e-19 - - - - - - - -
NLEFIACL_02627 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NLEFIACL_02628 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NLEFIACL_02629 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
NLEFIACL_02630 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
NLEFIACL_02631 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
NLEFIACL_02632 1.06e-16 - - - - - - - -
NLEFIACL_02633 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
NLEFIACL_02634 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
NLEFIACL_02635 7.62e-290 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
NLEFIACL_02636 5.02e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NLEFIACL_02637 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02638 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NLEFIACL_02639 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NLEFIACL_02640 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NLEFIACL_02641 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NLEFIACL_02642 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NLEFIACL_02643 7.06e-93 - - - S - - - Protein of unknown function (DUF1694)
NLEFIACL_02644 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NLEFIACL_02645 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
NLEFIACL_02646 1.62e-105 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_02647 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_02648 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NLEFIACL_02649 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NLEFIACL_02650 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
NLEFIACL_02651 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_02652 2.62e-100 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_02653 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
NLEFIACL_02654 1.17e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NLEFIACL_02655 1.18e-146 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLEFIACL_02656 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLEFIACL_02657 2.58e-186 yxeH - - S - - - hydrolase
NLEFIACL_02658 8.95e-225 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLEFIACL_02660 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NLEFIACL_02661 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NLEFIACL_02662 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NLEFIACL_02663 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NLEFIACL_02664 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NLEFIACL_02665 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_02666 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_02667 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_02668 3.25e-252 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
NLEFIACL_02669 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NLEFIACL_02670 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_02671 1.73e-178 yleF - - K - - - Helix-turn-helix domain, rpiR family
NLEFIACL_02672 1.48e-103 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLEFIACL_02673 1.17e-96 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_02674 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_02675 4.72e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NLEFIACL_02676 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLEFIACL_02677 1.07e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NLEFIACL_02678 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NLEFIACL_02679 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_02680 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NLEFIACL_02681 2.05e-203 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NLEFIACL_02682 1.25e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NLEFIACL_02683 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02684 5.44e-174 - - - K - - - UTRA domain
NLEFIACL_02685 2.63e-200 estA - - S - - - Putative esterase
NLEFIACL_02686 2.09e-83 - - - - - - - -
NLEFIACL_02687 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
NLEFIACL_02688 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
NLEFIACL_02689 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
NLEFIACL_02690 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NLEFIACL_02691 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLEFIACL_02692 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLEFIACL_02693 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
NLEFIACL_02694 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
NLEFIACL_02695 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLEFIACL_02696 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLEFIACL_02697 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLEFIACL_02698 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NLEFIACL_02699 4.07e-85 - - - S - - - pyridoxamine 5-phosphate
NLEFIACL_02700 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NLEFIACL_02701 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02702 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NLEFIACL_02703 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NLEFIACL_02704 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NLEFIACL_02705 2.72e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NLEFIACL_02706 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NLEFIACL_02707 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLEFIACL_02708 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NLEFIACL_02709 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NLEFIACL_02710 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02711 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NLEFIACL_02712 1.31e-128 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NLEFIACL_02713 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
NLEFIACL_02714 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
NLEFIACL_02715 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NLEFIACL_02716 2.49e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NLEFIACL_02717 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NLEFIACL_02718 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02719 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NLEFIACL_02720 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NLEFIACL_02721 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NLEFIACL_02722 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NLEFIACL_02723 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLEFIACL_02724 1.15e-282 - - - S - - - associated with various cellular activities
NLEFIACL_02725 9.34e-317 - - - S - - - Putative metallopeptidase domain
NLEFIACL_02726 1.03e-65 - - - - - - - -
NLEFIACL_02727 9.96e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
NLEFIACL_02728 7.83e-60 - - - - - - - -
NLEFIACL_02729 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_02730 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
NLEFIACL_02731 7.47e-235 - - - S - - - Cell surface protein
NLEFIACL_02732 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NLEFIACL_02733 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NLEFIACL_02734 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLEFIACL_02735 8.1e-82 - - - L - - - IS30 family
NLEFIACL_02736 2.26e-41 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
NLEFIACL_02737 6.22e-169 - - - L - - - Transposase and inactivated derivatives, IS30 family
NLEFIACL_02738 4.49e-74 - - - L - - - Transposase DDE domain
NLEFIACL_02739 1.43e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NLEFIACL_02740 0.0 - 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 Cadmium transporter
NLEFIACL_02741 2.06e-70 cadC - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NLEFIACL_02742 2.35e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
NLEFIACL_02744 1.87e-48 - - - L - - - recombinase activity
NLEFIACL_02745 9.72e-146 - - - S - - - membrane
NLEFIACL_02746 5.72e-99 - - - K - - - LytTr DNA-binding domain
NLEFIACL_02747 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
NLEFIACL_02748 0.0 - - - S - - - membrane
NLEFIACL_02749 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NLEFIACL_02750 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NLEFIACL_02751 3.24e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLEFIACL_02752 2.47e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NLEFIACL_02753 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NLEFIACL_02754 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NLEFIACL_02755 6.61e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NLEFIACL_02756 1.15e-89 yqhL - - P - - - Rhodanese-like protein
NLEFIACL_02757 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NLEFIACL_02758 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NLEFIACL_02759 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLEFIACL_02760 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NLEFIACL_02761 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NLEFIACL_02762 1.77e-205 - - - - - - - -
NLEFIACL_02763 1.34e-232 - - - - - - - -
NLEFIACL_02764 4.14e-126 - - - S - - - Protein conserved in bacteria
NLEFIACL_02765 5.37e-74 - - - - - - - -
NLEFIACL_02766 2.97e-41 - - - - - - - -
NLEFIACL_02770 9.81e-27 - - - - - - - -
NLEFIACL_02771 6.69e-124 - - - K - - - Transcriptional regulator
NLEFIACL_02772 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NLEFIACL_02773 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NLEFIACL_02774 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NLEFIACL_02775 1e-247 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NLEFIACL_02776 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLEFIACL_02777 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NLEFIACL_02778 5.46e-89 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLEFIACL_02779 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLEFIACL_02780 3.99e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLEFIACL_02781 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLEFIACL_02782 5.49e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NLEFIACL_02783 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NLEFIACL_02784 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NLEFIACL_02785 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NLEFIACL_02786 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02787 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02788 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NLEFIACL_02789 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_02790 2.38e-72 - - - - - - - -
NLEFIACL_02791 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NLEFIACL_02792 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLEFIACL_02793 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLEFIACL_02794 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLEFIACL_02795 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLEFIACL_02796 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLEFIACL_02797 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NLEFIACL_02798 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NLEFIACL_02799 9.9e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLEFIACL_02800 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NLEFIACL_02801 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NLEFIACL_02802 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NLEFIACL_02803 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
NLEFIACL_02804 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NLEFIACL_02805 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLEFIACL_02806 1.79e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLEFIACL_02807 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLEFIACL_02808 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLEFIACL_02809 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NLEFIACL_02810 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLEFIACL_02811 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLEFIACL_02812 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLEFIACL_02813 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NLEFIACL_02814 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NLEFIACL_02815 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLEFIACL_02816 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NLEFIACL_02817 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLEFIACL_02818 1.03e-66 - - - - - - - -
NLEFIACL_02820 1.28e-51 - - - - - - - -
NLEFIACL_02821 9.28e-58 - - - - - - - -
NLEFIACL_02822 1.27e-109 - - - K - - - MarR family
NLEFIACL_02823 0.0 - - - D - - - nuclear chromosome segregation
NLEFIACL_02824 0.0 inlJ - - M - - - MucBP domain
NLEFIACL_02825 6.58e-24 - - - - - - - -
NLEFIACL_02826 3.26e-24 - - - - - - - -
NLEFIACL_02827 1.56e-22 - - - - - - - -
NLEFIACL_02828 1.07e-26 - - - - - - - -
NLEFIACL_02829 9.35e-24 - - - - - - - -
NLEFIACL_02830 2.16e-26 - - - - - - - -
NLEFIACL_02831 4.63e-24 - - - - - - - -
NLEFIACL_02832 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
NLEFIACL_02833 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02834 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_02835 2.1e-33 - - - - - - - -
NLEFIACL_02836 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NLEFIACL_02837 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NLEFIACL_02838 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
NLEFIACL_02839 0.0 yclK - - T - - - Histidine kinase
NLEFIACL_02840 1.39e-171 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NLEFIACL_02841 8.61e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NLEFIACL_02842 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NLEFIACL_02843 2.55e-218 - - - EG - - - EamA-like transporter family
NLEFIACL_02845 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
NLEFIACL_02846 5.34e-64 - - - - - - - -
NLEFIACL_02847 6.55e-272 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
NLEFIACL_02848 8.05e-178 - - - F - - - NUDIX domain
NLEFIACL_02849 2.68e-32 - - - - - - - -
NLEFIACL_02851 8.16e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NLEFIACL_02852 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
NLEFIACL_02853 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NLEFIACL_02854 2.29e-48 - - - - - - - -
NLEFIACL_02855 1.11e-45 - - - - - - - -
NLEFIACL_02856 4.86e-279 - - - T - - - diguanylate cyclase
NLEFIACL_02857 0.0 - - - S - - - ABC transporter, ATP-binding protein
NLEFIACL_02858 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
NLEFIACL_02859 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
NLEFIACL_02860 3.84e-185 - - - S - - - Peptidase_C39 like family
NLEFIACL_02861 2.94e-227 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NLEFIACL_02862 1.54e-144 - - - - - - - -
NLEFIACL_02863 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLEFIACL_02864 1.97e-110 - - - S - - - Pfam:DUF3816
NLEFIACL_02865 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NLEFIACL_02866 2.72e-90 - - - M - - - LysM domain
NLEFIACL_02867 1.14e-79 - - - M - - - LysM domain protein
NLEFIACL_02868 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02869 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NLEFIACL_02870 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NLEFIACL_02871 2.17e-222 - - - S - - - Conserved hypothetical protein 698
NLEFIACL_02872 7.69e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NLEFIACL_02873 5.97e-106 - - - S - - - Domain of unknown function (DUF4811)
NLEFIACL_02874 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NLEFIACL_02875 4.35e-164 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NLEFIACL_02876 3.46e-251 - - - EGP - - - Major Facilitator Superfamily
NLEFIACL_02877 7.43e-28 - - - M - - - domain protein
NLEFIACL_02878 2.68e-71 - - - M - - - domain protein
NLEFIACL_02879 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
NLEFIACL_02880 4.43e-129 - - - - - - - -
NLEFIACL_02881 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NLEFIACL_02882 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
NLEFIACL_02883 6.59e-227 - - - K - - - LysR substrate binding domain
NLEFIACL_02884 5.67e-232 - - - M - - - Peptidase family S41
NLEFIACL_02885 2.24e-277 - - - - - - - -
NLEFIACL_02886 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NLEFIACL_02887 0.0 yhaN - - L - - - AAA domain
NLEFIACL_02888 5e-293 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NLEFIACL_02889 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
NLEFIACL_02890 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NLEFIACL_02891 2.43e-18 - - - - - - - -
NLEFIACL_02892 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NLEFIACL_02893 9.65e-272 arcT - - E - - - Aminotransferase
NLEFIACL_02894 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NLEFIACL_02895 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NLEFIACL_02896 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLEFIACL_02897 1.41e-147 yciB - - M - - - ErfK YbiS YcfS YnhG
NLEFIACL_02898 1.1e-70 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NLEFIACL_02899 1.14e-191 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NLEFIACL_02900 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NLEFIACL_02901 1.02e-285 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLEFIACL_02902 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLEFIACL_02903 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NLEFIACL_02904 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
NLEFIACL_02905 0.0 celR - - K - - - PRD domain
NLEFIACL_02906 6.25e-138 - - - - - - - -
NLEFIACL_02907 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NLEFIACL_02908 3.81e-105 - - - - - - - -
NLEFIACL_02909 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NLEFIACL_02910 5.77e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
NLEFIACL_02913 1.79e-42 - - - - - - - -
NLEFIACL_02914 2.69e-316 dinF - - V - - - MatE
NLEFIACL_02915 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
NLEFIACL_02916 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NLEFIACL_02917 5.68e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
NLEFIACL_02918 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NLEFIACL_02919 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NLEFIACL_02920 0.0 - - - S - - - Protein conserved in bacteria
NLEFIACL_02921 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLEFIACL_02922 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NLEFIACL_02923 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
NLEFIACL_02924 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
NLEFIACL_02925 3.89e-237 - - - - - - - -
NLEFIACL_02926 5.24e-15 - - - - - - - -
NLEFIACL_02927 4.29e-87 - - - - - - - -
NLEFIACL_02930 0.0 uvrA2 - - L - - - ABC transporter
NLEFIACL_02931 7.12e-62 - - - - - - - -
NLEFIACL_02932 8.82e-119 - - - - - - - -
NLEFIACL_02933 1.34e-33 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_02934 2.44e-51 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NLEFIACL_02935 4.31e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NLEFIACL_02936 4.56e-78 - - - - - - - -
NLEFIACL_02937 5.37e-74 - - - - - - - -
NLEFIACL_02938 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NLEFIACL_02939 5.95e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NLEFIACL_02940 7.83e-140 - - - - - - - -
NLEFIACL_02941 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLEFIACL_02942 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NLEFIACL_02943 1.64e-151 - - - GM - - - NAD(P)H-binding
NLEFIACL_02944 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
NLEFIACL_02945 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLEFIACL_02946 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
NLEFIACL_02947 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLEFIACL_02948 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NLEFIACL_02950 8.5e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NLEFIACL_02951 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLEFIACL_02952 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
NLEFIACL_02953 1.56e-161 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NLEFIACL_02954 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLEFIACL_02955 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLEFIACL_02956 4.59e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_02957 4.15e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NLEFIACL_02958 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
NLEFIACL_02959 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NLEFIACL_02960 1.83e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLEFIACL_02961 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NLEFIACL_02962 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NLEFIACL_02963 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NLEFIACL_02964 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NLEFIACL_02965 3.54e-121 mraW1 - - J - - - Putative rRNA methylase
NLEFIACL_02966 9.32e-40 - - - - - - - -
NLEFIACL_02967 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02968 8.82e-125 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02969 1.25e-207 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02970 0.0 - - - S - - - Pfam Methyltransferase
NLEFIACL_02971 7.05e-304 - - - N - - - Cell shape-determining protein MreB
NLEFIACL_02972 0.0 mdr - - EGP - - - Major Facilitator
NLEFIACL_02973 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLEFIACL_02974 5.79e-158 - - - - - - - -
NLEFIACL_02975 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NLEFIACL_02976 3.91e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NLEFIACL_02977 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NLEFIACL_02978 2.08e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NLEFIACL_02979 8.01e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NLEFIACL_02981 1.7e-199 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NLEFIACL_02982 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
NLEFIACL_02983 2.07e-123 - - - - - - - -
NLEFIACL_02984 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
NLEFIACL_02985 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
NLEFIACL_02997 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLEFIACL_02998 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLEFIACL_02999 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NLEFIACL_03000 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NLEFIACL_03001 7.93e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
NLEFIACL_03002 7.11e-201 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLEFIACL_03003 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLEFIACL_03004 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NLEFIACL_03005 1.51e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NLEFIACL_03006 1.72e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLEFIACL_03007 9.73e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLEFIACL_03008 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NLEFIACL_03009 4.47e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
NLEFIACL_03010 1.85e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLEFIACL_03011 1.3e-110 queT - - S - - - QueT transporter
NLEFIACL_03012 4.87e-148 - - - S - - - (CBS) domain
NLEFIACL_03013 0.0 - - - S - - - Putative peptidoglycan binding domain
NLEFIACL_03014 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NLEFIACL_03015 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLEFIACL_03016 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLEFIACL_03017 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NLEFIACL_03018 7.72e-57 yabO - - J - - - S4 domain protein
NLEFIACL_03020 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NLEFIACL_03021 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
NLEFIACL_03022 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLEFIACL_03023 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NLEFIACL_03024 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLEFIACL_03025 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLEFIACL_03026 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLEFIACL_03027 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NLEFIACL_03028 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NLEFIACL_03029 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
NLEFIACL_03030 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLEFIACL_03031 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NLEFIACL_03032 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NLEFIACL_03033 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLEFIACL_03034 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NLEFIACL_03035 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NLEFIACL_03036 3.55e-127 ywjB - - H - - - RibD C-terminal domain
NLEFIACL_03037 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLEFIACL_03038 1.05e-153 - - - S - - - Membrane
NLEFIACL_03039 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
NLEFIACL_03040 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)