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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IANEGIEI_00001	3.02e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IANEGIEI_00002	1.73e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IANEGIEI_00003	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANEGIEI_00004	3.13e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IANEGIEI_00005	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
IANEGIEI_00006	1.18e-163	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
IANEGIEI_00007	3.15e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IANEGIEI_00008	1.26e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IANEGIEI_00009	1.46e-135	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IANEGIEI_00010	1.49e-253	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IANEGIEI_00011	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IANEGIEI_00012	5.44e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IANEGIEI_00013	8.11e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IANEGIEI_00014	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IANEGIEI_00015	0.0	ydaO	-	-	E	-	-	-	amino acid
IANEGIEI_00016	4.12e-50	-	-	-	-	-	-	-	-
IANEGIEI_00017	4e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IANEGIEI_00018	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IANEGIEI_00019	1.25e-165	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IANEGIEI_00020	3.26e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IANEGIEI_00021	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IANEGIEI_00022	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IANEGIEI_00023	2.31e-69	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
IANEGIEI_00024	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IANEGIEI_00025	6.84e-227	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IANEGIEI_00026	2.26e-210	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IANEGIEI_00027	5.26e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IANEGIEI_00028	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IANEGIEI_00029	1.06e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IANEGIEI_00030	2.73e-283	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IANEGIEI_00031	4.89e-238	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IANEGIEI_00032	1.06e-99	yphH	-	-	S	-	-	-	Cupin domain
IANEGIEI_00033	6.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IANEGIEI_00034	2.21e-42	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IANEGIEI_00035	1.64e-98	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IANEGIEI_00036	5.26e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00037	6.26e-170	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IANEGIEI_00038	1.47e-116	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
IANEGIEI_00039	2.72e-52	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IANEGIEI_00040	6.04e-37	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IANEGIEI_00041	8.68e-97	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IANEGIEI_00042	7.09e-70	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
IANEGIEI_00045	2.57e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IANEGIEI_00046	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IANEGIEI_00047	1.07e-281	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
IANEGIEI_00048	5.86e-32	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_00050	9.45e-109	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_00051	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IANEGIEI_00052	6.52e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IANEGIEI_00053	3.32e-42	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IANEGIEI_00054	6.4e-140	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IANEGIEI_00055	2.22e-67	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IANEGIEI_00056	1.08e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IANEGIEI_00058	1.32e-170	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00059	3.09e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IANEGIEI_00060	6.6e-230	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IANEGIEI_00061	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IANEGIEI_00062	7.78e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
IANEGIEI_00064	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IANEGIEI_00065	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
IANEGIEI_00066	4.8e-208	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANEGIEI_00067	1.05e-44	ydzE	-	-	EG	-	-	-	spore germination
IANEGIEI_00068	2.99e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IANEGIEI_00069	7.94e-113	-	-	-	-	-	-	-	-
IANEGIEI_00070	0.0	-	-	-	M	-	-	-	Iron Transport-associated domain
IANEGIEI_00071	8.47e-128	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
IANEGIEI_00072	7.66e-194	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IANEGIEI_00073	1.14e-187	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANEGIEI_00074	7.38e-180	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00075	3.89e-302	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IANEGIEI_00076	1.35e-201	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IANEGIEI_00077	5.65e-135	-	-	-	K	-	-	-	acetyltransferase
IANEGIEI_00078	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IANEGIEI_00079	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IANEGIEI_00080	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IANEGIEI_00081	5.64e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IANEGIEI_00082	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IANEGIEI_00083	2.67e-75	-	-	-	K	-	-	-	transcriptional regulator
IANEGIEI_00084	4.68e-36	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IANEGIEI_00085	3.52e-108	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IANEGIEI_00086	2.87e-223	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IANEGIEI_00087	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IANEGIEI_00088	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IANEGIEI_00089	1.04e-209	-	-	-	C	-	-	-	Aldo keto reductase
IANEGIEI_00090	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IANEGIEI_00091	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IANEGIEI_00092	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IANEGIEI_00093	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
IANEGIEI_00094	1.11e-45	-	-	-	-	-	-	-	-
IANEGIEI_00095	3.13e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IANEGIEI_00096	8.6e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_00097	6.12e-230	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IANEGIEI_00098	5.75e-242	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IANEGIEI_00099	3.89e-36	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00100	1.6e-14	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00102	2.79e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IANEGIEI_00103	3.27e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
IANEGIEI_00104	1.91e-09	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IANEGIEI_00106	2.8e-150	pnb	-	-	C	-	-	-	nitroreductase
IANEGIEI_00107	2.33e-106	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
IANEGIEI_00109	8.67e-43	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IANEGIEI_00110	3.01e-81	-	-	-	C	-	-	-	Aldo keto reductase
IANEGIEI_00111	5.11e-06	-	-	-	S	-	-	-	CsbD-like
IANEGIEI_00113	2.12e-36	-	-	-	C	-	-	-	Aldo/keto reductase family
IANEGIEI_00114	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
IANEGIEI_00115	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
IANEGIEI_00116	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
IANEGIEI_00117	3.9e-197	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_00118	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IANEGIEI_00119	1.82e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
IANEGIEI_00120	1.77e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
IANEGIEI_00122	2.54e-18	-	-	-	S	-	-	-	Homeodomain-like domain
IANEGIEI_00123	5.29e-155	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IANEGIEI_00124	1.77e-201	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
IANEGIEI_00125	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IANEGIEI_00126	5.74e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IANEGIEI_00127	5.57e-224	-	-	-	-	-	-	-	-
IANEGIEI_00128	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
IANEGIEI_00129	1.53e-19	-	-	-	-	-	-	-	-
IANEGIEI_00130	9.34e-274	-	-	-	L	ko:K07485	-	ko00000	Transposase
IANEGIEI_00131	7.99e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IANEGIEI_00132	3.03e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IANEGIEI_00133	6.24e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IANEGIEI_00134	3.89e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IANEGIEI_00135	4.82e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IANEGIEI_00136	1.76e-199	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IANEGIEI_00137	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IANEGIEI_00138	4.62e-92	-	-	-	-	-	-	-	-
IANEGIEI_00139	6.27e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IANEGIEI_00140	1.4e-236	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IANEGIEI_00141	4.68e-180	-	-	-	-	-	-	-	-
IANEGIEI_00142	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IANEGIEI_00143	2.65e-108	-	-	-	M	-	-	-	PFAM NLP P60 protein
IANEGIEI_00144	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IANEGIEI_00145	1.28e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IANEGIEI_00146	1.01e-210	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IANEGIEI_00147	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IANEGIEI_00152	2.93e-201	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IANEGIEI_00153	1.59e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IANEGIEI_00154	3.72e-145	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IANEGIEI_00155	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IANEGIEI_00156	4.82e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IANEGIEI_00157	1.35e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IANEGIEI_00158	7.62e-138	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IANEGIEI_00159	4.05e-136	-	-	-	S	-	-	-	polysaccharide biosynthetic process
IANEGIEI_00160	3.76e-43	wcaB	2.3.1.30	-	E	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
IANEGIEI_00162	4.66e-37	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IANEGIEI_00163	2.3e-79	-	-	-	-	-	-	-	-
IANEGIEI_00164	5.13e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
IANEGIEI_00165	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IANEGIEI_00166	7.54e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IANEGIEI_00167	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IANEGIEI_00168	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IANEGIEI_00169	2.94e-152	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IANEGIEI_00170	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IANEGIEI_00171	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IANEGIEI_00172	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IANEGIEI_00173	9.75e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IANEGIEI_00174	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IANEGIEI_00175	1.52e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IANEGIEI_00176	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IANEGIEI_00178	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IANEGIEI_00179	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IANEGIEI_00180	4.1e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IANEGIEI_00181	2.27e-191	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IANEGIEI_00182	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IANEGIEI_00183	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IANEGIEI_00184	7.22e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IANEGIEI_00185	2.06e-282	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IANEGIEI_00186	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IANEGIEI_00187	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IANEGIEI_00188	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IANEGIEI_00189	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IANEGIEI_00190	3.6e-208	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IANEGIEI_00191	1.07e-108	-	-	-	L	-	-	-	nuclease
IANEGIEI_00192	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IANEGIEI_00193	4.42e-62	-	-	-	-	-	-	-	-
IANEGIEI_00194	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IANEGIEI_00195	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
IANEGIEI_00196	5.3e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IANEGIEI_00197	8.16e-209	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IANEGIEI_00198	2.9e-158	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00199	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IANEGIEI_00200	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IANEGIEI_00201	1.58e-280	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IANEGIEI_00202	4.28e-29	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_00203	1.23e-170	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_00204	9.16e-35	-	-	-	-	-	-	-	-
IANEGIEI_00205	3.8e-135	-	-	-	-	-	-	-	-
IANEGIEI_00206	9.3e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IANEGIEI_00207	1.76e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IANEGIEI_00208	3.05e-73	-	-	-	-	-	-	-	-
IANEGIEI_00209	3.69e-158	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IANEGIEI_00211	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IANEGIEI_00212	8.13e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IANEGIEI_00213	2.14e-258	-	-	-	S	-	-	-	associated with various cellular activities
IANEGIEI_00214	4.63e-266	-	-	-	S	-	-	-	Putative metallopeptidase domain
IANEGIEI_00215	5.76e-59	-	-	-	-	-	-	-	-
IANEGIEI_00216	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IANEGIEI_00217	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IANEGIEI_00218	4.73e-118	ymdB	-	-	S	-	-	-	Macro domain protein
IANEGIEI_00219	1.02e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IANEGIEI_00220	4.77e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IANEGIEI_00221	2.44e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_00222	9.08e-71	-	-	-	-	-	-	-	-
IANEGIEI_00223	1.8e-179	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IANEGIEI_00224	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IANEGIEI_00225	9.76e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00226	1.21e-48	-	-	-	-	-	-	-	-
IANEGIEI_00227	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IANEGIEI_00228	1.8e-180	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IANEGIEI_00229	2.22e-230	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IANEGIEI_00230	8.51e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IANEGIEI_00231	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IANEGIEI_00232	1.1e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IANEGIEI_00233	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IANEGIEI_00234	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IANEGIEI_00235	6.79e-304	dinF	-	-	V	-	-	-	MatE
IANEGIEI_00236	6.01e-42	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
IANEGIEI_00237	2.89e-56	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
IANEGIEI_00238	2.66e-95	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
IANEGIEI_00239	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IANEGIEI_00240	1.02e-297	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IANEGIEI_00241	2.71e-200	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IANEGIEI_00242	9.87e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IANEGIEI_00243	2.8e-116	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IANEGIEI_00244	3.56e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IANEGIEI_00245	4.42e-166	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IANEGIEI_00246	8.01e-129	-	-	-	-	-	-	-	-
IANEGIEI_00247	2.33e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
IANEGIEI_00248	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IANEGIEI_00250	2.05e-100	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
IANEGIEI_00251	2.06e-39	-	-	-	C	-	-	-	Flavodoxin
IANEGIEI_00252	9.92e-56	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
IANEGIEI_00253	1.62e-43	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IANEGIEI_00254	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
IANEGIEI_00255	1.42e-66	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IANEGIEI_00256	3.34e-158	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IANEGIEI_00257	3.32e-145	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
IANEGIEI_00258	1.09e-271	msmK2	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IANEGIEI_00259	1.75e-313	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IANEGIEI_00260	8.34e-194	-	-	-	U	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IANEGIEI_00261	1.37e-181	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IANEGIEI_00262	3.58e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IANEGIEI_00263	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IANEGIEI_00264	1.89e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IANEGIEI_00272	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
IANEGIEI_00273	1.61e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IANEGIEI_00274	7.55e-167	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IANEGIEI_00275	4.98e-19	ysnF	-	-	S	-	-	-	Heat induced stress protein YflT
IANEGIEI_00276	1.11e-150	-	-	-	-	-	-	-	-
IANEGIEI_00277	3.66e-237	ysdE	-	-	P	-	-	-	Citrate transporter
IANEGIEI_00278	1.06e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IANEGIEI_00279	5.74e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IANEGIEI_00280	6.25e-26	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IANEGIEI_00281	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IANEGIEI_00282	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IANEGIEI_00283	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IANEGIEI_00285	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
IANEGIEI_00286	1.2e-31	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IANEGIEI_00287	4.32e-71	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
IANEGIEI_00288	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IANEGIEI_00289	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IANEGIEI_00290	6.56e-273	-	-	-	G	-	-	-	Transporter, major facilitator family protein
IANEGIEI_00291	2.41e-280	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IANEGIEI_00292	1.4e-207	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IANEGIEI_00293	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IANEGIEI_00294	2.43e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IANEGIEI_00295	1.89e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IANEGIEI_00296	6.61e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IANEGIEI_00297	1.66e-40	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
IANEGIEI_00298	7.02e-87	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
IANEGIEI_00299	1.85e-78	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANEGIEI_00300	5.09e-36	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IANEGIEI_00301	1.09e-195	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
IANEGIEI_00302	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IANEGIEI_00303	6.29e-25	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IANEGIEI_00304	2.01e-77	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IANEGIEI_00305	7.92e-30	-	-	-	S	-	-	-	cog cog1302
IANEGIEI_00306	4.68e-198	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
IANEGIEI_00307	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
IANEGIEI_00312	3.45e-201	yueF	-	-	S	-	-	-	AI-2E family transporter
IANEGIEI_00313	1.48e-200	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IANEGIEI_00314	2.93e-10	-	-	-	-	-	-	-	-
IANEGIEI_00315	5.36e-66	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
IANEGIEI_00318	8.34e-101	-	-	-	-	-	-	-	-
IANEGIEI_00330	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IANEGIEI_00331	1.25e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IANEGIEI_00332	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IANEGIEI_00333	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IANEGIEI_00334	1.71e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IANEGIEI_00335	7.88e-233	camS	-	-	S	-	-	-	sex pheromone
IANEGIEI_00336	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IANEGIEI_00337	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IANEGIEI_00338	4.32e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IANEGIEI_00339	3.74e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IANEGIEI_00340	1.58e-140	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IANEGIEI_00341	2.48e-177	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IANEGIEI_00342	2.03e-24	-	-	-	S	-	-	-	interspecies interaction between organisms
IANEGIEI_00343	1.6e-17	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IANEGIEI_00353	3.24e-10	-	-	-	-	-	-	-	-
IANEGIEI_00355	1.55e-74	-	-	-	-	-	-	-	-
IANEGIEI_00357	8.69e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IANEGIEI_00358	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IANEGIEI_00359	7.54e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
IANEGIEI_00360	3.36e-154	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IANEGIEI_00361	1.68e-109	-	-	-	K	-	-	-	GNAT family
IANEGIEI_00363	9.76e-12	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IANEGIEI_00364	5.84e-194	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_00365	2.47e-113	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IANEGIEI_00366	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IANEGIEI_00367	4.76e-45	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
IANEGIEI_00368	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
IANEGIEI_00369	1.07e-300	-	-	-	F	ko:K03458	-	ko00000	Permease
IANEGIEI_00370	1.44e-197	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
IANEGIEI_00371	1.04e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IANEGIEI_00372	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IANEGIEI_00373	1.3e-144	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IANEGIEI_00374	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IANEGIEI_00375	1.97e-30	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IANEGIEI_00376	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IANEGIEI_00377	5.08e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IANEGIEI_00378	2.05e-10	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IANEGIEI_00379	5.57e-55	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IANEGIEI_00380	3.82e-160	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	Transporter
IANEGIEI_00381	8.77e-178	-	-	-	L	-	-	-	PFAM Integrase catalytic region
IANEGIEI_00382	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IANEGIEI_00383	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IANEGIEI_00384	2.87e-250	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
IANEGIEI_00385	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IANEGIEI_00386	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IANEGIEI_00387	5.56e-76	-	-	-	GM	-	-	-	NmrA-like family
IANEGIEI_00388	5.73e-210	-	-	-	K	-	-	-	LysR substrate binding domain
IANEGIEI_00389	2.78e-204	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IANEGIEI_00390	1.52e-141	-	-	-	-	-	-	-	-
IANEGIEI_00392	0.0	potE	-	-	E	-	-	-	Amino Acid
IANEGIEI_00393	9.69e-175	-	-	-	V	-	-	-	Beta-lactamase enzyme family
IANEGIEI_00394	6.4e-281	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IANEGIEI_00395	9.69e-122	-	-	-	-	-	-	-	-
IANEGIEI_00396	4.79e-250	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IANEGIEI_00397	1.72e-135	-	-	-	I	-	-	-	PAP2 superfamily
IANEGIEI_00398	5.37e-72	-	-	-	S	-	-	-	MazG-like family
IANEGIEI_00399	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IANEGIEI_00400	9.11e-92	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IANEGIEI_00401	3.13e-122	-	-	-	K	-	-	-	transcriptional regulator
IANEGIEI_00402	7.07e-286	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IANEGIEI_00405	4.7e-51	-	-	-	S	-	-	-	Cytochrome B5
IANEGIEI_00406	2.41e-54	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
IANEGIEI_00407	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
IANEGIEI_00410	6.02e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF998)
IANEGIEI_00411	9.4e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IANEGIEI_00412	6.35e-208	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IANEGIEI_00413	2.09e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IANEGIEI_00414	9.99e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IANEGIEI_00415	1.36e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IANEGIEI_00416	6.33e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IANEGIEI_00417	1.04e-227	-	-	-	K	-	-	-	WYL domain
IANEGIEI_00418	9.34e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IANEGIEI_00419	6.75e-42	-	-	-	-	-	-	-	-
IANEGIEI_00420	1.21e-80	-	-	-	-	-	-	-	-
IANEGIEI_00421	1.93e-142	yicL	-	-	EG	-	-	-	EamA-like transporter family
IANEGIEI_00422	7.21e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IANEGIEI_00423	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IANEGIEI_00424	3.05e-211	-	-	-	K	-	-	-	LysR substrate binding domain
IANEGIEI_00425	1.73e-59	rssA	-	-	S	-	-	-	Phospholipase, patatin family
IANEGIEI_00426	1.83e-109	rssA	-	-	S	-	-	-	Phospholipase, patatin family
IANEGIEI_00427	5.17e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IANEGIEI_00428	1.66e-232	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
IANEGIEI_00429	2.69e-28	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IANEGIEI_00430	4.77e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
IANEGIEI_00431	1.53e-245	flp	-	-	V	-	-	-	Beta-lactamase
IANEGIEI_00432	5.35e-289	-	-	-	-	-	-	-	-
IANEGIEI_00434	1.4e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IANEGIEI_00435	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IANEGIEI_00436	2.25e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IANEGIEI_00437	7.21e-205	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IANEGIEI_00438	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IANEGIEI_00440	2.26e-91	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IANEGIEI_00441	1.9e-99	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IANEGIEI_00442	7.35e-63	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IANEGIEI_00443	6.34e-40	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IANEGIEI_00444	2.23e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IANEGIEI_00445	1.69e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
IANEGIEI_00446	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
IANEGIEI_00447	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
IANEGIEI_00449	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IANEGIEI_00450	7.99e-135	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IANEGIEI_00451	9.67e-309	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_00453	4.89e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IANEGIEI_00454	9.61e-62	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IANEGIEI_00455	1.47e-58	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IANEGIEI_00456	3.59e-11	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IANEGIEI_00457	3.48e-32	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IANEGIEI_00458	1.03e-67	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IANEGIEI_00459	2.34e-42	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
IANEGIEI_00460	1.18e-152	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
IANEGIEI_00461	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
IANEGIEI_00462	4.46e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IANEGIEI_00463	1.27e-123	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IANEGIEI_00464	3.07e-51	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IANEGIEI_00465	1.43e-66	-	-	-	S	-	-	-	Fic/DOC family
IANEGIEI_00466	3.49e-41	-	-	-	S	-	-	-	Fic/DOC family
IANEGIEI_00467	6.37e-101	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
IANEGIEI_00468	1.51e-313	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
IANEGIEI_00469	1.09e-225	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
IANEGIEI_00470	4.98e-272	-	-	-	E	-	-	-	Aminotransferase
IANEGIEI_00473	3.71e-150	-	-	-	S	-	-	-	Phage minor capsid protein 2
IANEGIEI_00474	1.09e-71	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IANEGIEI_00475	1.37e-120	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IANEGIEI_00476	3.04e-80	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IANEGIEI_00477	1.41e-06	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
IANEGIEI_00479	7.68e-202	-	-	-	S	-	-	-	DUF218 domain
IANEGIEI_00480	1.14e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
IANEGIEI_00481	3.07e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IANEGIEI_00482	3.53e-165	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IANEGIEI_00483	4.02e-300	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
IANEGIEI_00484	2.53e-115	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IANEGIEI_00485	7.19e-260	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IANEGIEI_00486	2.3e-228	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IANEGIEI_00487	1.35e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IANEGIEI_00488	4.78e-249	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IANEGIEI_00489	4.62e-150	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
IANEGIEI_00490	2.28e-131	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IANEGIEI_00491	6.34e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00492	6.02e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IANEGIEI_00493	5.49e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
IANEGIEI_00494	5.75e-98	ywnA	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_00495	3.54e-95	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
IANEGIEI_00496	2.36e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IANEGIEI_00497	4.25e-77	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_00498	4.94e-32	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_00499	6e-59	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IANEGIEI_00500	2.01e-34	-	-	-	C	-	-	-	Flavodoxin
IANEGIEI_00501	4.29e-94	-	-	-	GM	-	-	-	NmrA-like family
IANEGIEI_00502	3.74e-58	-	-	-	K	-	-	-	transcriptional regulator
IANEGIEI_00503	1.54e-138	-	-	-	L	-	-	-	Integrase
IANEGIEI_00504	6.11e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IANEGIEI_00505	1.22e-92	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IANEGIEI_00507	1.98e-46	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IANEGIEI_00514	2.36e-120	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
IANEGIEI_00515	2.13e-191	-	-	-	L	-	-	-	DNA replication protein
IANEGIEI_00518	5.96e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
IANEGIEI_00519	1.82e-215	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IANEGIEI_00520	2.42e-262	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IANEGIEI_00523	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
IANEGIEI_00524	5.12e-206	-	-	-	S	-	-	-	Phage tail protein
IANEGIEI_00525	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IANEGIEI_00526	3.55e-64	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
IANEGIEI_00527	6.19e-123	-	-	-	S	-	-	-	Phage tail tube protein
IANEGIEI_00529	3.29e-09	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IANEGIEI_00531	3.05e-63	-	-	-	-	-	-	-	-
IANEGIEI_00532	2.05e-228	-	-	-	G	ko:K06904	-	ko00000	Phage capsid family
IANEGIEI_00533	1.22e-230	-	-	-	S	-	-	-	Phage portal protein
IANEGIEI_00535	0.0	-	-	-	S	-	-	-	Phage Terminase
IANEGIEI_00536	4.64e-98	-	-	-	L	-	-	-	Phage terminase, small subunit
IANEGIEI_00537	1.04e-55	-	-	-	-	-	-	-	-
IANEGIEI_00541	1.16e-195	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
IANEGIEI_00542	5.01e-64	-	-	-	S	-	-	-	Domain of unknown function (DUF4298)
IANEGIEI_00543	6.8e-111	-	-	-	-	-	-	-	-
IANEGIEI_00544	6.13e-53	-	-	-	L	-	-	-	MULE transposase domain
IANEGIEI_00545	1.19e-163	sptS	-	-	T	-	-	-	Histidine kinase
IANEGIEI_00546	1.65e-101	dltr	-	-	K	-	-	-	response regulator
IANEGIEI_00547	3.33e-146	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IANEGIEI_00548	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IANEGIEI_00549	4.84e-159	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IANEGIEI_00551	7.2e-49	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IANEGIEI_00552	0.000109	-	-	-	L	-	-	-	Integrase core domain
IANEGIEI_00553	3.05e-99	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
IANEGIEI_00554	6.72e-16	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IANEGIEI_00555	9.92e-96	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IANEGIEI_00556	2.75e-89	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
IANEGIEI_00557	5.72e-82	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
IANEGIEI_00558	1.91e-164	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
IANEGIEI_00559	2.07e-35	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
IANEGIEI_00560	1.55e-176	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
IANEGIEI_00561	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
IANEGIEI_00562	2.68e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IANEGIEI_00563	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IANEGIEI_00564	1.29e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IANEGIEI_00565	3.07e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IANEGIEI_00566	2.82e-280	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_00567	2.8e-256	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IANEGIEI_00568	5.5e-133	-	-	-	C	-	-	-	aldo keto reductase
IANEGIEI_00569	7.75e-138	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IANEGIEI_00571	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IANEGIEI_00572	1.82e-254	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IANEGIEI_00573	5.98e-66	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
IANEGIEI_00574	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IANEGIEI_00575	3.49e-145	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IANEGIEI_00576	4.35e-84	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IANEGIEI_00577	1.41e-24	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IANEGIEI_00578	3.29e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IANEGIEI_00579	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IANEGIEI_00580	1.39e-86	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IANEGIEI_00581	7.79e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IANEGIEI_00582	1.92e-80	-	-	-	-	-	-	-	-
IANEGIEI_00583	4.6e-55	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IANEGIEI_00584	5.5e-179	-	-	-	S	-	-	-	interspecies interaction between organisms
IANEGIEI_00585	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IANEGIEI_00586	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IANEGIEI_00587	6.64e-187	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IANEGIEI_00588	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANEGIEI_00589	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANEGIEI_00590	5.62e-189	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANEGIEI_00591	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IANEGIEI_00592	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANEGIEI_00593	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IANEGIEI_00594	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IANEGIEI_00595	2.6e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IANEGIEI_00596	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IANEGIEI_00597	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IANEGIEI_00598	7.83e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IANEGIEI_00599	4.09e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IANEGIEI_00600	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IANEGIEI_00601	2.08e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IANEGIEI_00602	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IANEGIEI_00603	1.19e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IANEGIEI_00604	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IANEGIEI_00605	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IANEGIEI_00606	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IANEGIEI_00607	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IANEGIEI_00608	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IANEGIEI_00609	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IANEGIEI_00610	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IANEGIEI_00611	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IANEGIEI_00612	2.49e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IANEGIEI_00613	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IANEGIEI_00614	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IANEGIEI_00615	1.35e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IANEGIEI_00616	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IANEGIEI_00617	9.04e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IANEGIEI_00618	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IANEGIEI_00619	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IANEGIEI_00620	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IANEGIEI_00621	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IANEGIEI_00622	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IANEGIEI_00623	1.41e-39	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
IANEGIEI_00624	6.09e-275	-	-	-	-	-	-	-	-
IANEGIEI_00625	4.84e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IANEGIEI_00626	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANEGIEI_00627	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANEGIEI_00628	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IANEGIEI_00629	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IANEGIEI_00630	5.23e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IANEGIEI_00631	1.86e-24	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
IANEGIEI_00632	1.87e-230	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IANEGIEI_00634	1.6e-182	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IANEGIEI_00636	8.36e-245	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IANEGIEI_00638	3.25e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
IANEGIEI_00639	6.19e-113	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
IANEGIEI_00640	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
IANEGIEI_00641	7.65e-39	-	-	-	S	ko:K08987	-	ko00000	membrane
IANEGIEI_00642	3.68e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
IANEGIEI_00643	1.01e-59	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IANEGIEI_00644	2.65e-149	-	-	-	Q	-	-	-	Methyltransferase domain
IANEGIEI_00646	4.53e-132	-	-	-	S	-	-	-	CAAX protease self-immunity
IANEGIEI_00647	2.34e-124	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IANEGIEI_00648	1.33e-55	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IANEGIEI_00649	7.68e-63	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IANEGIEI_00651	3.97e-18	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_00652	7.77e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IANEGIEI_00653	2.09e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IANEGIEI_00654	1.01e-132	-	-	-	-	-	-	-	-
IANEGIEI_00655	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IANEGIEI_00656	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IANEGIEI_00657	1.43e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IANEGIEI_00658	1.67e-176	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IANEGIEI_00659	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_00660	3.71e-205	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IANEGIEI_00661	1.8e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IANEGIEI_00662	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IANEGIEI_00663	3.61e-242	mocA	-	-	S	-	-	-	Oxidoreductase
IANEGIEI_00664	8.28e-308	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IANEGIEI_00667	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IANEGIEI_00668	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IANEGIEI_00669	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IANEGIEI_00670	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
IANEGIEI_00671	1.61e-189	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IANEGIEI_00672	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IANEGIEI_00674	4.24e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IANEGIEI_00675	1.66e-150	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IANEGIEI_00676	1.15e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IANEGIEI_00677	5.55e-48	-	-	-	M	-	-	-	biosynthesis protein
IANEGIEI_00678	8.2e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IANEGIEI_00679	3.42e-90	-	-	-	-	-	-	-	-
IANEGIEI_00680	1.2e-112	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IANEGIEI_00681	2.3e-56	cps3I	-	-	G	-	-	-	Acyltransferase family
IANEGIEI_00682	3.07e-100	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
IANEGIEI_00683	6e-268	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IANEGIEI_00684	4.09e-277	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IANEGIEI_00685	6.68e-90	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
IANEGIEI_00686	1.93e-117	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IANEGIEI_00687	2.42e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IANEGIEI_00688	5.32e-130	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IANEGIEI_00689	5.62e-120	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IANEGIEI_00690	1.39e-258	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IANEGIEI_00691	9.62e-270	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IANEGIEI_00692	7.43e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IANEGIEI_00693	1.53e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IANEGIEI_00694	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IANEGIEI_00695	1.34e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IANEGIEI_00696	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IANEGIEI_00697	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IANEGIEI_00698	4.24e-187	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IANEGIEI_00699	3.33e-243	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IANEGIEI_00700	7.74e-204	-	-	-	EG	-	-	-	EamA-like transporter family
IANEGIEI_00701	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IANEGIEI_00702	6.95e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IANEGIEI_00703	6e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IANEGIEI_00704	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IANEGIEI_00705	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IANEGIEI_00706	3.52e-270	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
IANEGIEI_00707	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
IANEGIEI_00708	4.48e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IANEGIEI_00709	5.38e-243	arcT	-	-	E	-	-	-	Dipeptidase
IANEGIEI_00710	2.13e-254	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IANEGIEI_00711	9.1e-227	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IANEGIEI_00712	5.49e-86	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IANEGIEI_00713	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IANEGIEI_00715	2.27e-77	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
IANEGIEI_00716	2.76e-82	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IANEGIEI_00717	1.2e-89	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
IANEGIEI_00718	4.18e-114	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
IANEGIEI_00719	7.67e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IANEGIEI_00720	7.93e-147	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IANEGIEI_00721	4.37e-166	epsB	-	-	M	-	-	-	biosynthesis protein
IANEGIEI_00722	1.4e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IANEGIEI_00723	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IANEGIEI_00724	2.66e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IANEGIEI_00725	1.01e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IANEGIEI_00726	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IANEGIEI_00727	5.91e-186	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IANEGIEI_00728	2.71e-208	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IANEGIEI_00729	6.1e-172	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IANEGIEI_00730	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IANEGIEI_00731	8.55e-270	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
IANEGIEI_00732	9.05e-22	-	-	-	-	-	-	-	-
IANEGIEI_00733	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IANEGIEI_00734	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IANEGIEI_00735	8.38e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IANEGIEI_00736	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IANEGIEI_00737	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IANEGIEI_00738	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IANEGIEI_00739	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IANEGIEI_00740	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IANEGIEI_00741	5.23e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IANEGIEI_00742	9.6e-139	-	-	-	-	-	-	-	-
IANEGIEI_00743	1.07e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IANEGIEI_00744	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IANEGIEI_00745	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IANEGIEI_00746	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IANEGIEI_00747	1.1e-130	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IANEGIEI_00748	5.51e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IANEGIEI_00749	2.67e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IANEGIEI_00750	8e-150	ybbR	-	-	S	-	-	-	YbbR-like protein
IANEGIEI_00751	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IANEGIEI_00752	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IANEGIEI_00753	2.55e-68	-	-	-	-	-	-	-	-
IANEGIEI_00754	1.44e-263	oatA	-	-	I	-	-	-	Acyltransferase
IANEGIEI_00755	8.31e-191	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IANEGIEI_00756	1.15e-106	lytE	-	-	M	-	-	-	Lysin motif
IANEGIEI_00757	9.46e-220	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IANEGIEI_00758	1.16e-213	-	-	-	K	-	-	-	LysR substrate binding domain
IANEGIEI_00759	3.31e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IANEGIEI_00760	1.82e-190	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IANEGIEI_00761	1.46e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IANEGIEI_00762	3.59e-64	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IANEGIEI_00763	9.4e-119	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IANEGIEI_00764	1.28e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IANEGIEI_00765	3.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IANEGIEI_00766	3.23e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IANEGIEI_00767	7.33e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
IANEGIEI_00769	1.14e-169	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IANEGIEI_00770	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IANEGIEI_00771	7.15e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IANEGIEI_00772	4.99e-273	xylR	-	-	GK	-	-	-	ROK family
IANEGIEI_00773	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANEGIEI_00774	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IANEGIEI_00775	3.4e-23	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
IANEGIEI_00776	5.13e-313	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
IANEGIEI_00777	3.4e-92	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IANEGIEI_00778	3.8e-99	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IANEGIEI_00779	1.58e-143	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IANEGIEI_00780	3.74e-100	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IANEGIEI_00781	3.14e-276	-	-	-	G	-	-	-	Major Facilitator
IANEGIEI_00782	6.5e-38	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IANEGIEI_00783	1.03e-154	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IANEGIEI_00784	4.12e-60	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IANEGIEI_00785	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
IANEGIEI_00786	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IANEGIEI_00787	1.39e-127	-	-	-	S	-	-	-	Plasmid replication protein
IANEGIEI_00789	1.37e-14	-	-	-	-	-	-	-	-
IANEGIEI_00790	3.14e-116	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IANEGIEI_00791	1.46e-270	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IANEGIEI_00792	5.57e-103	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IANEGIEI_00793	2.45e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IANEGIEI_00794	2.82e-39	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IANEGIEI_00795	2.11e-37	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IANEGIEI_00796	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IANEGIEI_00797	1.25e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IANEGIEI_00798	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IANEGIEI_00799	1.86e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IANEGIEI_00800	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IANEGIEI_00801	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IANEGIEI_00802	1.37e-182	yidA	-	-	S	-	-	-	hydrolase
IANEGIEI_00803	1.13e-64	-	-	-	-	-	-	-	-
IANEGIEI_00804	1.73e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IANEGIEI_00805	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IANEGIEI_00806	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IANEGIEI_00807	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IANEGIEI_00808	1.29e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IANEGIEI_00809	8.16e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IANEGIEI_00810	7.82e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IANEGIEI_00811	2.94e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IANEGIEI_00812	1.53e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IANEGIEI_00813	7.76e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IANEGIEI_00814	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IANEGIEI_00815	3.89e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IANEGIEI_00816	1.95e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
IANEGIEI_00817	3.83e-164	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IANEGIEI_00818	7.22e-237	-	-	-	-	-	-	-	-
IANEGIEI_00819	4.16e-281	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IANEGIEI_00820	2.19e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IANEGIEI_00821	0.0	-	-	-	L	-	-	-	DNA helicase
IANEGIEI_00822	8.65e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IANEGIEI_00823	2.6e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IANEGIEI_00825	1.23e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IANEGIEI_00827	7.41e-115	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_00828	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IANEGIEI_00829	1.74e-249	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IANEGIEI_00830	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
IANEGIEI_00831	8.06e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IANEGIEI_00832	2.52e-156	-	-	-	C	-	-	-	nitroreductase
IANEGIEI_00833	1.58e-111	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
IANEGIEI_00834	2.79e-254	-	-	-	C	ko:K02381	-	ko00000	COG0074 Succinyl-CoA synthetase, alpha subunit
IANEGIEI_00835	1.09e-57	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
IANEGIEI_00836	1.24e-24	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
IANEGIEI_00837	4.47e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_00838	8.56e-236	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IANEGIEI_00839	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IANEGIEI_00840	2e-142	-	-	-	-	-	-	-	-
IANEGIEI_00841	1.06e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IANEGIEI_00842	9.66e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IANEGIEI_00843	7.01e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IANEGIEI_00844	4.35e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IANEGIEI_00845	3.1e-131	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
IANEGIEI_00846	1.2e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IANEGIEI_00847	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
IANEGIEI_00848	1.42e-255	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
IANEGIEI_00850	2.68e-50	-	-	-	-	-	-	-	-
IANEGIEI_00852	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IANEGIEI_00853	6.15e-161	-	-	-	S	-	-	-	Membrane
IANEGIEI_00854	1.84e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IANEGIEI_00855	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IANEGIEI_00856	2.19e-225	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IANEGIEI_00857	3.38e-112	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_00859	7.4e-178	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANEGIEI_00860	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IANEGIEI_00861	7.14e-105	usp5	-	-	T	-	-	-	universal stress protein
IANEGIEI_00862	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IANEGIEI_00863	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IANEGIEI_00864	5.97e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IANEGIEI_00865	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
IANEGIEI_00866	1.7e-106	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IANEGIEI_00867	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IANEGIEI_00868	3.4e-116	-	-	-	GM	-	-	-	epimerase
IANEGIEI_00869	6.93e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IANEGIEI_00870	1.46e-105	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
IANEGIEI_00871	7.15e-122	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
IANEGIEI_00872	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IANEGIEI_00873	7.07e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IANEGIEI_00874	1.14e-294	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IANEGIEI_00875	1.41e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IANEGIEI_00876	1.06e-34	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IANEGIEI_00877	0.00031	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IANEGIEI_00878	3.52e-235	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IANEGIEI_00879	2.53e-134	-	-	-	NU	-	-	-	mannosyl-glycoprotein
IANEGIEI_00880	5.71e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IANEGIEI_00881	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
IANEGIEI_00882	3.06e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IANEGIEI_00883	1.55e-59	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IANEGIEI_00884	3.88e-22	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IANEGIEI_00885	1.04e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IANEGIEI_00886	9.56e-243	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IANEGIEI_00887	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IANEGIEI_00888	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IANEGIEI_00889	8.18e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
IANEGIEI_00890	4.07e-270	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
IANEGIEI_00891	2.89e-228	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_00892	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
IANEGIEI_00893	1.08e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IANEGIEI_00894	3.72e-193	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IANEGIEI_00896	3.69e-316	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IANEGIEI_00897	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
IANEGIEI_00898	6.73e-80	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IANEGIEI_00899	2.74e-09	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IANEGIEI_00900	1.03e-199	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IANEGIEI_00901	5.24e-36	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
IANEGIEI_00902	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IANEGIEI_00903	4.13e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IANEGIEI_00904	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANEGIEI_00905	7.62e-132	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_00906	4.95e-24	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IANEGIEI_00907	9.08e-215	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
IANEGIEI_00908	3.45e-74	-	-	-	S	-	-	-	FMN_bind
IANEGIEI_00909	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_00910	1.29e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IANEGIEI_00911	8.89e-253	-	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
IANEGIEI_00912	4.36e-67	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IANEGIEI_00913	7.03e-65	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
IANEGIEI_00914	1.1e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
IANEGIEI_00915	3.63e-220	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
IANEGIEI_00916	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
IANEGIEI_00917	4.09e-136	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IANEGIEI_00918	2.13e-89	-	-	-	-	-	-	-	-
IANEGIEI_00919	6.18e-85	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IANEGIEI_00920	9.85e-270	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IANEGIEI_00921	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
IANEGIEI_00922	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IANEGIEI_00923	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IANEGIEI_00924	1.32e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IANEGIEI_00925	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IANEGIEI_00926	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IANEGIEI_00927	3.23e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IANEGIEI_00928	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IANEGIEI_00929	1.24e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
IANEGIEI_00930	3.15e-134	-	-	-	-	-	-	-	-
IANEGIEI_00932	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IANEGIEI_00933	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IANEGIEI_00934	3.67e-246	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IANEGIEI_00935	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IANEGIEI_00936	5.67e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IANEGIEI_00937	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IANEGIEI_00938	7.34e-214	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IANEGIEI_00939	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IANEGIEI_00940	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IANEGIEI_00941	1.18e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IANEGIEI_00942	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IANEGIEI_00943	1.51e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IANEGIEI_00944	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IANEGIEI_00945	1.53e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IANEGIEI_00946	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IANEGIEI_00947	7.64e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IANEGIEI_00948	4.32e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IANEGIEI_00949	7.64e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IANEGIEI_00950	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IANEGIEI_00951	1.7e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IANEGIEI_00952	3.16e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IANEGIEI_00953	4.19e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IANEGIEI_00955	4.76e-203	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IANEGIEI_00956	1.99e-88	-	-	-	M	-	-	-	LysM domain protein
IANEGIEI_00957	2.96e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IANEGIEI_00958	2.29e-101	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IANEGIEI_00959	1.33e-153	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IANEGIEI_00962	3.91e-31	-	-	-	-	-	-	-	-
IANEGIEI_00963	7.46e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IANEGIEI_00964	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IANEGIEI_00965	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_00966	7.03e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IANEGIEI_00967	3.23e-64	-	-	-	-	-	-	-	-
IANEGIEI_00968	6e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IANEGIEI_00969	4.23e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IANEGIEI_00970	5.97e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IANEGIEI_00971	6.62e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IANEGIEI_00972	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IANEGIEI_00973	4.03e-56	-	-	-	-	-	-	-	-
IANEGIEI_00974	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IANEGIEI_00975	9.22e-37	-	-	-	S	-	-	-	Domain of unknown function DUF302
IANEGIEI_00976	3.25e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IANEGIEI_00977	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IANEGIEI_00978	3.34e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IANEGIEI_00979	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IANEGIEI_00980	7.09e-97	-	-	-	L	-	-	-	PFAM Integrase catalytic region
IANEGIEI_00981	4.58e-150	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IANEGIEI_00982	5.91e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IANEGIEI_00983	2.34e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IANEGIEI_00984	5.36e-93	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IANEGIEI_00985	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IANEGIEI_00986	5.81e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IANEGIEI_00987	4.27e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IANEGIEI_00988	8.46e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IANEGIEI_00989	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IANEGIEI_00990	2.06e-150	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IANEGIEI_00991	1.35e-209	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IANEGIEI_00992	2.82e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_00993	3.7e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IANEGIEI_00994	9.52e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IANEGIEI_00995	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IANEGIEI_00996	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
IANEGIEI_00997	6.22e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IANEGIEI_00998	4.59e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IANEGIEI_00999	4.34e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IANEGIEI_01000	1.18e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IANEGIEI_01001	1.35e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
IANEGIEI_01002	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IANEGIEI_01003	6.07e-40	-	-	-	-	-	-	-	-
IANEGIEI_01004	3.13e-141	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
IANEGIEI_01005	5.42e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IANEGIEI_01006	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IANEGIEI_01007	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IANEGIEI_01008	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IANEGIEI_01009	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
IANEGIEI_01010	1.37e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IANEGIEI_01011	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01012	1.96e-145	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IANEGIEI_01013	3.57e-22	-	-	-	-	-	-	-	-
IANEGIEI_01014	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IANEGIEI_01015	1.31e-244	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
IANEGIEI_01016	1.34e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IANEGIEI_01017	1.5e-96	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_01018	1.07e-200	-	-	-	-	-	-	-	-
IANEGIEI_01019	4.83e-10	-	-	-	-	-	-	-	-
IANEGIEI_01020	1.79e-77	-	-	-	-	-	-	-	-
IANEGIEI_01021	7.24e-97	uspA3	-	-	T	-	-	-	universal stress protein
IANEGIEI_01023	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IANEGIEI_01024	1.06e-311	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_01025	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IANEGIEI_01026	6.58e-173	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
IANEGIEI_01027	9.05e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IANEGIEI_01028	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IANEGIEI_01029	1.58e-244	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IANEGIEI_01030	2.65e-54	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
IANEGIEI_01031	4.66e-57	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IANEGIEI_01032	7.75e-163	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IANEGIEI_01033	4.93e-138	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
IANEGIEI_01034	2.27e-183	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IANEGIEI_01035	1.55e-53	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IANEGIEI_01036	9.93e-69	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IANEGIEI_01037	1.65e-19	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IANEGIEI_01038	5.62e-166	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
IANEGIEI_01039	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IANEGIEI_01040	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_01041	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IANEGIEI_01042	1.85e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IANEGIEI_01043	9.59e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
IANEGIEI_01044	2.79e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IANEGIEI_01045	3.38e-252	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
IANEGIEI_01046	4.27e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IANEGIEI_01047	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
IANEGIEI_01048	4.53e-239	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IANEGIEI_01049	0.0	potE	-	-	E	-	-	-	Amino Acid
IANEGIEI_01050	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IANEGIEI_01051	1.62e-186	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IANEGIEI_01052	3.13e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IANEGIEI_01053	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IANEGIEI_01054	3.11e-166	-	-	-	-	-	-	-	-
IANEGIEI_01055	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IANEGIEI_01056	1.25e-197	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IANEGIEI_01057	4.25e-68	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IANEGIEI_01059	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANEGIEI_01060	4.28e-180	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IANEGIEI_01061	9e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IANEGIEI_01062	8.03e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IANEGIEI_01063	1.32e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IANEGIEI_01064	4.18e-89	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IANEGIEI_01065	9.02e-48	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IANEGIEI_01067	5.86e-87	-	-	-	K	-	-	-	LysR substrate binding domain
IANEGIEI_01068	1.35e-206	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IANEGIEI_01072	6.19e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IANEGIEI_01073	1.2e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IANEGIEI_01074	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IANEGIEI_01075	3.12e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IANEGIEI_01076	1.1e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
IANEGIEI_01077	5.15e-90	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IANEGIEI_01078	3.62e-36	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IANEGIEI_01079	7.36e-83	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IANEGIEI_01080	5.26e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IANEGIEI_01081	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IANEGIEI_01082	3.43e-101	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
IANEGIEI_01083	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01084	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IANEGIEI_01085	2.18e-244	ampC	-	-	V	-	-	-	Beta-lactamase
IANEGIEI_01086	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IANEGIEI_01087	2.31e-63	-	-	-	-	-	-	-	-
IANEGIEI_01088	2.15e-180	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IANEGIEI_01089	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IANEGIEI_01090	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IANEGIEI_01091	4.39e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IANEGIEI_01092	5.28e-201	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IANEGIEI_01093	2.66e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IANEGIEI_01094	1.05e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IANEGIEI_01095	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IANEGIEI_01096	1.65e-251	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IANEGIEI_01097	4.51e-164	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IANEGIEI_01098	9.03e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IANEGIEI_01099	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IANEGIEI_01100	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IANEGIEI_01101	1.31e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IANEGIEI_01102	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IANEGIEI_01103	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IANEGIEI_01104	7.25e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IANEGIEI_01105	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IANEGIEI_01106	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IANEGIEI_01107	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IANEGIEI_01108	6.3e-274	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
IANEGIEI_01109	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IANEGIEI_01110	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IANEGIEI_01111	2.82e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IANEGIEI_01113	1.56e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IANEGIEI_01114	3.95e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IANEGIEI_01115	2.22e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IANEGIEI_01116	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
IANEGIEI_01118	4.34e-299	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IANEGIEI_01119	3.15e-108	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IANEGIEI_01120	5.1e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
IANEGIEI_01121	2.3e-173	-	-	-	S	-	-	-	Membrane
IANEGIEI_01122	2.47e-189	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IANEGIEI_01123	1.66e-68	-	-	-	V	-	-	-	Abi-like protein
IANEGIEI_01124	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IANEGIEI_01125	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IANEGIEI_01126	2.77e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IANEGIEI_01127	6.8e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IANEGIEI_01128	3.95e-278	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IANEGIEI_01129	1.11e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IANEGIEI_01130	1.34e-43	-	-	-	M	-	-	-	LysM domain
IANEGIEI_01132	2.33e-19	-	-	-	S	-	-	-	zinc-ribbon domain
IANEGIEI_01135	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IANEGIEI_01136	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IANEGIEI_01137	1.9e-312	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IANEGIEI_01138	1.08e-146	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IANEGIEI_01139	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IANEGIEI_01140	1.95e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IANEGIEI_01141	3.68e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IANEGIEI_01142	1.09e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IANEGIEI_01143	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01144	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IANEGIEI_01145	6.37e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IANEGIEI_01146	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
IANEGIEI_01147	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
IANEGIEI_01148	2.34e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IANEGIEI_01149	5.4e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IANEGIEI_01150	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IANEGIEI_01151	4.61e-298	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IANEGIEI_01152	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IANEGIEI_01153	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IANEGIEI_01154	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IANEGIEI_01155	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IANEGIEI_01156	2.44e-223	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
IANEGIEI_01157	3.17e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IANEGIEI_01158	4.44e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IANEGIEI_01159	1.9e-297	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IANEGIEI_01160	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IANEGIEI_01161	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IANEGIEI_01162	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IANEGIEI_01163	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IANEGIEI_01164	2.07e-207	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IANEGIEI_01165	9.07e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
IANEGIEI_01166	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IANEGIEI_01167	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IANEGIEI_01168	2.08e-283	-	-	-	P	-	-	-	Chloride transporter, ClC family
IANEGIEI_01169	3.4e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IANEGIEI_01170	3.23e-10	-	-	-	K	-	-	-	transcriptional regulator
IANEGIEI_01171	7.71e-210	ydbI	-	-	K	-	-	-	AI-2E family transporter
IANEGIEI_01172	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IANEGIEI_01173	3.36e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IANEGIEI_01174	1.61e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IANEGIEI_01175	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IANEGIEI_01176	7.67e-219	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
IANEGIEI_01177	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IANEGIEI_01178	7.16e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IANEGIEI_01179	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANEGIEI_01180	9.43e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANEGIEI_01181	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANEGIEI_01182	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IANEGIEI_01183	7.63e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IANEGIEI_01184	1.54e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IANEGIEI_01185	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IANEGIEI_01186	1.73e-305	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IANEGIEI_01187	2.24e-98	mleR	-	-	K	-	-	-	LysR family
IANEGIEI_01188	3.78e-290	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IANEGIEI_01189	4.29e-235	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IANEGIEI_01190	3.53e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IANEGIEI_01191	5.36e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IANEGIEI_01192	1.88e-315	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IANEGIEI_01193	2.31e-210	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IANEGIEI_01194	3.17e-314	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IANEGIEI_01195	8.61e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
IANEGIEI_01196	1.79e-268	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
IANEGIEI_01197	6.55e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IANEGIEI_01198	3.36e-61	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
IANEGIEI_01199	7.54e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
IANEGIEI_01200	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IANEGIEI_01201	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IANEGIEI_01202	8.07e-186	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IANEGIEI_01203	1.2e-204	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
IANEGIEI_01204	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IANEGIEI_01205	2.42e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
IANEGIEI_01206	2.83e-284	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANEGIEI_01207	2.54e-215	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
IANEGIEI_01208	1.15e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
IANEGIEI_01209	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IANEGIEI_01210	1.63e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IANEGIEI_01211	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IANEGIEI_01212	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IANEGIEI_01213	5.72e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IANEGIEI_01214	8.63e-93	-	-	-	F	-	-	-	Nudix hydrolase
IANEGIEI_01215	3.22e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IANEGIEI_01216	1.03e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IANEGIEI_01217	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IANEGIEI_01218	1.52e-211	-	-	-	-	-	-	-	-
IANEGIEI_01219	1.61e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IANEGIEI_01220	2.35e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
IANEGIEI_01221	1.44e-310	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
IANEGIEI_01222	4.06e-100	-	-	-	-	-	-	-	-
IANEGIEI_01224	1.36e-206	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IANEGIEI_01225	4.98e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_01226	1.02e-31	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IANEGIEI_01227	5.23e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IANEGIEI_01228	0.0	-	-	-	E	-	-	-	amino acid
IANEGIEI_01229	7.16e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IANEGIEI_01230	5.11e-251	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IANEGIEI_01231	1.89e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IANEGIEI_01232	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IANEGIEI_01233	3.27e-149	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IANEGIEI_01234	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IANEGIEI_01235	1.11e-203	-	-	-	EG	-	-	-	EamA-like transporter family
IANEGIEI_01236	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IANEGIEI_01237	1.75e-173	-	-	-	IQ	-	-	-	dehydrogenase reductase
IANEGIEI_01238	2.61e-193	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IANEGIEI_01239	1.4e-90	-	-	-	S	-	-	-	Nuclease-related domain
IANEGIEI_01242	3.8e-17	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
IANEGIEI_01250	9.24e-33	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
IANEGIEI_01251	1.53e-258	-	-	-	S	-	-	-	peptidoglycan catabolic process
IANEGIEI_01252	7.89e-38	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Anion-transporting ATPase
IANEGIEI_01254	1.12e-23	-	-	-	-	-	-	-	-
IANEGIEI_01257	1.02e-107	-	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
IANEGIEI_01258	1.93e-112	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_01261	8.3e-39	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IANEGIEI_01262	7.62e-142	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IANEGIEI_01263	2.35e-33	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IANEGIEI_01264	9.76e-22	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
IANEGIEI_01265	3.37e-271	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IANEGIEI_01266	5.09e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IANEGIEI_01267	1.62e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
IANEGIEI_01268	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IANEGIEI_01269	3.43e-147	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IANEGIEI_01270	2.68e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IANEGIEI_01271	8.95e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IANEGIEI_01272	1.28e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IANEGIEI_01273	5.39e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IANEGIEI_01274	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IANEGIEI_01275	1.08e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IANEGIEI_01276	2.38e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IANEGIEI_01277	2.87e-174	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IANEGIEI_01278	6.58e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IANEGIEI_01279	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IANEGIEI_01280	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IANEGIEI_01281	1.23e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IANEGIEI_01282	1.11e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IANEGIEI_01283	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IANEGIEI_01284	3.19e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
IANEGIEI_01285	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IANEGIEI_01286	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IANEGIEI_01287	1.08e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IANEGIEI_01288	1.62e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IANEGIEI_01289	5.24e-312	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IANEGIEI_01290	6.98e-105	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_01292	1.44e-188	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
IANEGIEI_01293	2.93e-100	-	-	-	S	-	-	-	Phage tail protein
IANEGIEI_01294	3.23e-302	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IANEGIEI_01296	3.95e-47	-	-	-	S	-	-	-	Phage tail tube protein
IANEGIEI_01297	5.5e-31	-	-	-	-	-	-	-	-
IANEGIEI_01298	9.15e-25	-	-	-	-	-	-	-	-
IANEGIEI_01299	7.26e-43	-	-	-	S	-	-	-	Phage head-tail joining protein
IANEGIEI_01300	2.49e-39	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IANEGIEI_01301	3.88e-151	-	-	-	S	-	-	-	Phage capsid family
IANEGIEI_01302	3.48e-99	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IANEGIEI_01303	1.47e-180	-	-	-	S	-	-	-	portal protein
IANEGIEI_01305	0.0	-	-	-	S	-	-	-	Phage Terminase
IANEGIEI_01306	2.69e-52	-	-	-	L	-	-	-	Phage terminase, small subunit
IANEGIEI_01307	1.23e-42	-	-	-	L	-	-	-	HNH nucleases
IANEGIEI_01308	2.3e-48	parB3	-	-	L	-	-	-	DNA methylase
IANEGIEI_01309	4.76e-305	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANEGIEI_01310	2.1e-218	-	-	-	GK	-	-	-	ROK family
IANEGIEI_01311	4.58e-54	-	-	-	-	-	-	-	-
IANEGIEI_01312	1.71e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IANEGIEI_01314	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IANEGIEI_01315	4.2e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IANEGIEI_01316	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IANEGIEI_01317	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IANEGIEI_01318	1.76e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IANEGIEI_01319	2.56e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IANEGIEI_01320	1.84e-197	-	-	-	D	-	-	-	DNA integration
IANEGIEI_01321	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IANEGIEI_01322	2.97e-211	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IANEGIEI_01323	4.13e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IANEGIEI_01324	1.64e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IANEGIEI_01325	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IANEGIEI_01326	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IANEGIEI_01327	1.66e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IANEGIEI_01328	1.99e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IANEGIEI_01329	2.92e-278	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
IANEGIEI_01330	5.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IANEGIEI_01331	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IANEGIEI_01332	3.62e-121	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IANEGIEI_01333	1.78e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IANEGIEI_01334	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01335	9.85e-281	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IANEGIEI_01336	1.81e-202	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IANEGIEI_01337	4e-297	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IANEGIEI_01338	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IANEGIEI_01339	1.23e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IANEGIEI_01340	1.09e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IANEGIEI_01341	3.8e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IANEGIEI_01342	1.54e-72	-	-	-	M	-	-	-	Lysin motif
IANEGIEI_01343	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IANEGIEI_01344	1.34e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
IANEGIEI_01345	3.93e-110	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IANEGIEI_01346	4.81e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IANEGIEI_01347	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IANEGIEI_01348	4.62e-180	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IANEGIEI_01349	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANEGIEI_01350	1.24e-183	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IANEGIEI_01351	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IANEGIEI_01352	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IANEGIEI_01353	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IANEGIEI_01355	3.28e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IANEGIEI_01356	3.31e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IANEGIEI_01357	3.26e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IANEGIEI_01358	6.86e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
IANEGIEI_01359	2.78e-292	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IANEGIEI_01360	8.27e-250	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IANEGIEI_01361	6.6e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IANEGIEI_01362	1.82e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IANEGIEI_01363	5.18e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IANEGIEI_01364	1.9e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IANEGIEI_01365	7.79e-109	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IANEGIEI_01366	5.46e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IANEGIEI_01367	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IANEGIEI_01368	2.91e-231	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IANEGIEI_01369	5.78e-215	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IANEGIEI_01370	2.41e-42	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_01371	3.07e-74	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_01373	3.93e-58	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_01374	1.5e-56	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_01375	2.23e-260	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IANEGIEI_01376	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IANEGIEI_01377	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IANEGIEI_01378	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IANEGIEI_01379	1.25e-198	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IANEGIEI_01380	3.63e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IANEGIEI_01381	5.17e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IANEGIEI_01382	3.97e-102	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IANEGIEI_01383	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IANEGIEI_01384	7.45e-85	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IANEGIEI_01385	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IANEGIEI_01386	7.47e-164	-	-	-	F	-	-	-	glutamine amidotransferase
IANEGIEI_01387	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IANEGIEI_01388	2.3e-313	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IANEGIEI_01389	3.49e-247	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IANEGIEI_01390	8.77e-190	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
IANEGIEI_01391	8.53e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
IANEGIEI_01392	4.55e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IANEGIEI_01393	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IANEGIEI_01394	3.89e-203	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IANEGIEI_01395	1.05e-16	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IANEGIEI_01396	6.07e-165	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IANEGIEI_01397	6.83e-173	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IANEGIEI_01400	4.57e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IANEGIEI_01401	2.07e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IANEGIEI_01402	1.01e-254	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IANEGIEI_01403	5.95e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
IANEGIEI_01404	1.75e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IANEGIEI_01405	2.61e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IANEGIEI_01406	1.09e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IANEGIEI_01407	2.11e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IANEGIEI_01408	2.95e-203	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IANEGIEI_01409	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IANEGIEI_01410	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IANEGIEI_01411	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IANEGIEI_01412	1.63e-74	-	-	-	-	-	-	-	-
IANEGIEI_01413	7.65e-104	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IANEGIEI_01414	2.01e-216	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IANEGIEI_01415	5.28e-31	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IANEGIEI_01416	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IANEGIEI_01417	1.56e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IANEGIEI_01418	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IANEGIEI_01419	8.4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IANEGIEI_01420	1.37e-186	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IANEGIEI_01421	1.49e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IANEGIEI_01422	7.08e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IANEGIEI_01423	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IANEGIEI_01424	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IANEGIEI_01425	1.02e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IANEGIEI_01426	3.58e-142	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IANEGIEI_01428	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IANEGIEI_01429	4.07e-43	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IANEGIEI_01430	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IANEGIEI_01431	2.68e-08	-	-	-	-	-	-	-	-
IANEGIEI_01432	6.58e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IANEGIEI_01433	3.74e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IANEGIEI_01434	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IANEGIEI_01435	0.0	-	-	-	S	-	-	-	amidohydrolase
IANEGIEI_01436	3.62e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IANEGIEI_01437	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IANEGIEI_01438	9.37e-159	-	-	-	S	-	-	-	repeat protein
IANEGIEI_01439	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IANEGIEI_01440	1.55e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IANEGIEI_01441	2.39e-98	-	-	-	P	-	-	-	ArsC family
IANEGIEI_01442	1.71e-238	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
IANEGIEI_01443	1.47e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IANEGIEI_01444	6.12e-98	-	-	-	-	-	-	-	-
IANEGIEI_01445	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IANEGIEI_01446	4.44e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IANEGIEI_01447	8e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IANEGIEI_01448	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IANEGIEI_01449	6.05e-262	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IANEGIEI_01450	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IANEGIEI_01451	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IANEGIEI_01452	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IANEGIEI_01453	5.62e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IANEGIEI_01454	1.21e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IANEGIEI_01455	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IANEGIEI_01456	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IANEGIEI_01457	2.71e-235	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IANEGIEI_01458	3.39e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IANEGIEI_01459	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IANEGIEI_01460	3.56e-65	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_01461	5.19e-223	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_01462	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IANEGIEI_01463	9.05e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
IANEGIEI_01464	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IANEGIEI_01465	9.07e-297	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IANEGIEI_01466	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IANEGIEI_01467	4.39e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IANEGIEI_01468	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IANEGIEI_01470	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01471	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IANEGIEI_01472	1.34e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IANEGIEI_01473	2.04e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IANEGIEI_01474	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IANEGIEI_01475	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IANEGIEI_01476	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IANEGIEI_01477	3.45e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
IANEGIEI_01478	3.19e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_01479	8.74e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
IANEGIEI_01480	2.49e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IANEGIEI_01481	9.06e-125	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
IANEGIEI_01482	1.14e-56	-	-	-	S	-	-	-	Protein conserved in bacteria
IANEGIEI_01483	2.01e-50	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IANEGIEI_01484	1.73e-67	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IANEGIEI_01485	1.59e-181	-	-	-	EG	-	-	-	EamA-like transporter family
IANEGIEI_01486	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IANEGIEI_01487	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
IANEGIEI_01488	1e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IANEGIEI_01489	4.44e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IANEGIEI_01490	6.94e-148	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IANEGIEI_01491	7.04e-168	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANEGIEI_01492	5.44e-255	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
IANEGIEI_01493	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IANEGIEI_01494	1.11e-208	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IANEGIEI_01495	3.55e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IANEGIEI_01497	4.55e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
IANEGIEI_01498	1.17e-39	-	-	-	-	-	-	-	-
IANEGIEI_01499	2.86e-90	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IANEGIEI_01500	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IANEGIEI_01501	6.63e-122	-	-	-	V	-	-	-	VanZ like family
IANEGIEI_01502	6.95e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IANEGIEI_01503	4.88e-76	-	-	-	-	-	-	-	-
IANEGIEI_01504	1.98e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_01505	6.7e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IANEGIEI_01506	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IANEGIEI_01507	2.76e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
IANEGIEI_01508	1.9e-258	-	-	-	M	-	-	-	domain protein
IANEGIEI_01510	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IANEGIEI_01511	6.67e-77	-	-	-	-	-	-	-	-
IANEGIEI_01512	7.38e-92	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IANEGIEI_01513	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IANEGIEI_01514	1.58e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IANEGIEI_01515	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IANEGIEI_01516	1.29e-313	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANEGIEI_01517	5.92e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
IANEGIEI_01518	3.16e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IANEGIEI_01519	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
IANEGIEI_01520	1.42e-215	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IANEGIEI_01522	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IANEGIEI_01523	3.35e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IANEGIEI_01524	6.44e-240	-	-	-	I	-	-	-	Alpha beta
IANEGIEI_01529	4.1e-76	-	-	-	S	-	-	-	VRR_NUC
IANEGIEI_01530	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
IANEGIEI_01531	2.9e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IANEGIEI_01532	2.14e-313	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IANEGIEI_01533	1.38e-154	-	-	-	S	-	-	-	AAA domain
IANEGIEI_01536	7.77e-20	-	-	-	S	-	-	-	HNH endonuclease
IANEGIEI_01539	1.14e-09	-	-	-	-	-	-	-	-
IANEGIEI_01542	2.67e-147	-	-	-	S	-	-	-	DNA binding
IANEGIEI_01543	2.91e-79	-	-	-	K	-	-	-	Peptidase S24-like
IANEGIEI_01544	1.17e-49	-	-	-	-	-	-	-	-
IANEGIEI_01545	3.46e-246	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IANEGIEI_01547	1.38e-120	-	-	-	-	-	-	-	-
IANEGIEI_01548	1.94e-100	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IANEGIEI_01549	4.48e-232	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_01551	2.12e-145	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IANEGIEI_01554	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IANEGIEI_01556	1.96e-237	-	-	-	EGP	-	-	-	Major Facilitator
IANEGIEI_01558	2.29e-140	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IANEGIEI_01560	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IANEGIEI_01561	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IANEGIEI_01562	6.72e-302	yycH	-	-	S	-	-	-	YycH protein
IANEGIEI_01563	3.79e-181	yycI	-	-	S	-	-	-	YycH protein
IANEGIEI_01564	4.51e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IANEGIEI_01565	2.9e-264	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IANEGIEI_01566	1.43e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IANEGIEI_01567	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_01568	9.34e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_01569	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IANEGIEI_01570	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IANEGIEI_01571	4.45e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IANEGIEI_01572	4.5e-138	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
IANEGIEI_01573	1.15e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IANEGIEI_01574	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IANEGIEI_01575	3.34e-273	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IANEGIEI_01576	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IANEGIEI_01577	1.37e-247	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IANEGIEI_01578	5.82e-273	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IANEGIEI_01579	3.21e-45	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
IANEGIEI_01580	2.85e-58	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
IANEGIEI_01581	4.42e-272	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IANEGIEI_01582	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IANEGIEI_01583	7e-269	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IANEGIEI_01584	1.19e-34	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_01585	6.67e-153	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
IANEGIEI_01586	6.98e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IANEGIEI_01587	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IANEGIEI_01588	3.58e-299	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IANEGIEI_01589	3.02e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IANEGIEI_01590	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IANEGIEI_01591	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IANEGIEI_01592	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IANEGIEI_01593	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IANEGIEI_01595	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IANEGIEI_01596	8.79e-42	-	-	-	-	-	-	-	-
IANEGIEI_01597	8.62e-05	-	-	-	-	-	-	-	-
IANEGIEI_01598	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IANEGIEI_01600	2.66e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IANEGIEI_01601	3.16e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
IANEGIEI_01602	2.88e-158	-	-	-	GM	-	-	-	NAD(P)H-binding
IANEGIEI_01603	5.66e-190	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IANEGIEI_01605	7.29e-112	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IANEGIEI_01606	1.04e-130	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IANEGIEI_01607	5.39e-46	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IANEGIEI_01609	5.95e-265	-	-	-	G	-	-	-	Major Facilitator Superfamily
IANEGIEI_01610	2.15e-14	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
IANEGIEI_01611	2.74e-72	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IANEGIEI_01612	2.01e-181	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IANEGIEI_01613	6.36e-131	-	-	-	-	-	-	-	-
IANEGIEI_01614	1.31e-203	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IANEGIEI_01615	5.33e-79	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IANEGIEI_01616	1.95e-99	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IANEGIEI_01617	4.33e-116	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IANEGIEI_01618	2.78e-273	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
IANEGIEI_01619	3.29e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANEGIEI_01620	4.97e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IANEGIEI_01621	3.15e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IANEGIEI_01622	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
IANEGIEI_01623	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IANEGIEI_01624	1.65e-44	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
IANEGIEI_01625	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IANEGIEI_01626	9.85e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IANEGIEI_01627	2.56e-289	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IANEGIEI_01628	5.04e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IANEGIEI_01629	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IANEGIEI_01630	1.69e-235	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IANEGIEI_01631	5.2e-276	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IANEGIEI_01632	2.02e-92	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IANEGIEI_01633	4.39e-40	-	-	-	S	-	-	-	Acyltransferase family
IANEGIEI_01634	1.12e-118	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
IANEGIEI_01635	5.87e-156	vanR	-	-	K	-	-	-	response regulator
IANEGIEI_01636	2.18e-267	hpk31	-	-	T	-	-	-	Histidine kinase
IANEGIEI_01637	3.45e-262	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IANEGIEI_01638	2.8e-176	-	-	-	E	-	-	-	AzlC protein
IANEGIEI_01639	4.31e-76	-	-	-	S	-	-	-	branched-chain amino acid
IANEGIEI_01644	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IANEGIEI_01645	2.71e-151	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IANEGIEI_01646	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IANEGIEI_01647	3.31e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IANEGIEI_01648	3.06e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IANEGIEI_01649	1.9e-256	-	-	-	-	-	-	-	-
IANEGIEI_01650	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IANEGIEI_01651	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IANEGIEI_01653	7.18e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IANEGIEI_01654	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IANEGIEI_01655	1.34e-172	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IANEGIEI_01656	3.22e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IANEGIEI_01657	4.82e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IANEGIEI_01659	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IANEGIEI_01660	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IANEGIEI_01661	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IANEGIEI_01662	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IANEGIEI_01663	3.01e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IANEGIEI_01664	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IANEGIEI_01665	2.74e-112	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IANEGIEI_01666	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IANEGIEI_01667	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
IANEGIEI_01668	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IANEGIEI_01669	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IANEGIEI_01670	2.61e-147	-	-	-	S	-	-	-	(CBS) domain
IANEGIEI_01671	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IANEGIEI_01672	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IANEGIEI_01673	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IANEGIEI_01674	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IANEGIEI_01675	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IANEGIEI_01676	5.22e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IANEGIEI_01677	1.94e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IANEGIEI_01678	4.28e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IANEGIEI_01679	5e-10	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
IANEGIEI_01680	7.48e-31	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
IANEGIEI_01681	8.02e-62	-	-	-	-	-	-	-	-
IANEGIEI_01682	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IANEGIEI_01683	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
IANEGIEI_01684	1.5e-194	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IANEGIEI_01685	2.73e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IANEGIEI_01686	3.68e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IANEGIEI_01687	1.56e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IANEGIEI_01688	7.99e-312	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IANEGIEI_01689	1.62e-249	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IANEGIEI_01690	1.08e-154	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IANEGIEI_01691	8.66e-313	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IANEGIEI_01692	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANEGIEI_01693	2.63e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IANEGIEI_01694	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANEGIEI_01695	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IANEGIEI_01696	1.75e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IANEGIEI_01697	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IANEGIEI_01698	3.66e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IANEGIEI_01700	2.18e-213	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IANEGIEI_01701	7.27e-86	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANEGIEI_01702	1.24e-111	-	-	-	S	-	-	-	integral membrane protein
IANEGIEI_01703	3.42e-279	-	-	-	L	-	-	-	Probable transposase
IANEGIEI_01704	6.78e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IANEGIEI_01706	4.82e-72	-	-	-	-	-	-	-	-
IANEGIEI_01707	3.03e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IANEGIEI_01708	1.43e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IANEGIEI_01709	1.72e-75	-	-	-	-	-	-	-	-
IANEGIEI_01710	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IANEGIEI_01711	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IANEGIEI_01712	5.86e-108	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_01713	4.1e-272	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IANEGIEI_01714	2.73e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IANEGIEI_01715	7.23e-77	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IANEGIEI_01716	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
IANEGIEI_01717	3.97e-97	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IANEGIEI_01718	2.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IANEGIEI_01719	1.21e-184	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
IANEGIEI_01720	3.62e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
IANEGIEI_01721	4.88e-107	-	-	-	S	-	-	-	MmgE/PrpD family
IANEGIEI_01723	2.67e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IANEGIEI_01724	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IANEGIEI_01725	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01726	5.25e-197	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IANEGIEI_01728	1.65e-222	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IANEGIEI_01729	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IANEGIEI_01730	4.61e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IANEGIEI_01731	5.02e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IANEGIEI_01732	3.29e-191	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IANEGIEI_01734	1.23e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IANEGIEI_01735	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01736	1.17e-269	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IANEGIEI_01737	4.53e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IANEGIEI_01738	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
IANEGIEI_01739	8.85e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IANEGIEI_01740	1.58e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IANEGIEI_01741	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IANEGIEI_01742	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IANEGIEI_01743	3.15e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
IANEGIEI_01744	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IANEGIEI_01745	1.26e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IANEGIEI_01746	1.62e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IANEGIEI_01747	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IANEGIEI_01748	6.96e-315	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IANEGIEI_01749	5.15e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IANEGIEI_01750	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IANEGIEI_01751	2.49e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IANEGIEI_01752	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IANEGIEI_01753	5.52e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IANEGIEI_01754	1.89e-122	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IANEGIEI_01755	1.73e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IANEGIEI_01756	1.09e-49	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IANEGIEI_01757	1.27e-117	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IANEGIEI_01758	1.85e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IANEGIEI_01759	5.63e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IANEGIEI_01760	2.47e-173	yqeM	-	-	Q	-	-	-	Methyltransferase
IANEGIEI_01761	4.41e-269	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IANEGIEI_01762	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IANEGIEI_01763	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IANEGIEI_01764	5.62e-155	csrR	-	-	K	-	-	-	response regulator
IANEGIEI_01765	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IANEGIEI_01766	2.1e-295	-	-	-	V	-	-	-	MatE
IANEGIEI_01767	3.2e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IANEGIEI_01768	9.66e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IANEGIEI_01769	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IANEGIEI_01770	5.9e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IANEGIEI_01771	5.12e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IANEGIEI_01772	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IANEGIEI_01773	2.58e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IANEGIEI_01774	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IANEGIEI_01775	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IANEGIEI_01776	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IANEGIEI_01777	0.0	-	-	-	S	-	-	-	membrane
IANEGIEI_01778	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IANEGIEI_01779	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IANEGIEI_01780	5.19e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IANEGIEI_01781	8.19e-133	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IANEGIEI_01782	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IANEGIEI_01783	8.69e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IANEGIEI_01784	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IANEGIEI_01785	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IANEGIEI_01786	1.48e-219	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IANEGIEI_01787	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IANEGIEI_01788	2.76e-18	-	-	-	-	-	-	-	-
IANEGIEI_01789	1.34e-201	-	-	-	-	-	-	-	-
IANEGIEI_01790	2.24e-224	-	-	-	-	-	-	-	-
IANEGIEI_01791	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
IANEGIEI_01792	6.86e-255	-	-	-	S	-	-	-	Phage integrase family
IANEGIEI_01794	9.35e-59	-	-	-	D	-	-	-	Anion-transporting ATPase
IANEGIEI_01796	6.64e-10	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IANEGIEI_01797	1.08e-81	-	-	-	K	-	-	-	Peptidase S24-like
IANEGIEI_01798	1.75e-11	-	-	-	K	-	-	-	sequence-specific DNA binding
IANEGIEI_01799	3.75e-158	-	-	-	S	-	-	-	DNA binding
IANEGIEI_01806	2.6e-05	-	-	-	L	-	-	-	Protein of unknown function (DUF968)
IANEGIEI_01807	1.13e-97	-	-	-	S	-	-	-	Single-strand binding protein family
IANEGIEI_01808	1.28e-175	-	-	-	S	-	-	-	calcium ion binding
IANEGIEI_01809	3.32e-55	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
IANEGIEI_01811	3.37e-14	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IANEGIEI_01812	1.03e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IANEGIEI_01816	1.07e-148	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
IANEGIEI_01817	1.76e-50	-	-	-	S	-	-	-	RloB-like protein
IANEGIEI_01818	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IANEGIEI_01819	2.16e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
IANEGIEI_01820	8.4e-211	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IANEGIEI_01821	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IANEGIEI_01822	3.62e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IANEGIEI_01823	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IANEGIEI_01824	6.69e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IANEGIEI_01825	1.67e-71	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IANEGIEI_01826	1.58e-61	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IANEGIEI_01827	3.78e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IANEGIEI_01828	1.33e-122	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IANEGIEI_01829	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IANEGIEI_01830	4.53e-263	yacL	-	-	S	-	-	-	domain protein
IANEGIEI_01831	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IANEGIEI_01832	7.92e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IANEGIEI_01833	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IANEGIEI_01834	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IANEGIEI_01835	1.01e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IANEGIEI_01836	1.31e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IANEGIEI_01837	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IANEGIEI_01838	1.01e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IANEGIEI_01839	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IANEGIEI_01840	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IANEGIEI_01841	2.78e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IANEGIEI_01842	4.1e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IANEGIEI_01843	6.43e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IANEGIEI_01844	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IANEGIEI_01845	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IANEGIEI_01846	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IANEGIEI_01847	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IANEGIEI_01848	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IANEGIEI_01849	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IANEGIEI_01851	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IANEGIEI_01852	1.48e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANEGIEI_01853	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANEGIEI_01854	1.28e-45	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IANEGIEI_01855	6.57e-107	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IANEGIEI_01857	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IANEGIEI_01858	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IANEGIEI_01859	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IANEGIEI_01860	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IANEGIEI_01861	6.36e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IANEGIEI_01862	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IANEGIEI_01863	1.12e-245	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IANEGIEI_01864	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IANEGIEI_01865	2.32e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IANEGIEI_01866	6.67e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IANEGIEI_01867	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IANEGIEI_01868	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IANEGIEI_01869	2.27e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IANEGIEI_01870	1.66e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IANEGIEI_01871	6.16e-200	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
IANEGIEI_01872	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IANEGIEI_01873	6.76e-217	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
IANEGIEI_01874	4.7e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
IANEGIEI_01875	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IANEGIEI_01876	2.27e-270	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IANEGIEI_01877	2.56e-271	arcT	-	-	E	-	-	-	Aminotransferase
IANEGIEI_01878	6.55e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IANEGIEI_01879	9.21e-142	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IANEGIEI_01880	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IANEGIEI_01882	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IANEGIEI_01883	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IANEGIEI_01884	4.21e-216	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IANEGIEI_01885	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IANEGIEI_01886	7.58e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IANEGIEI_01887	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IANEGIEI_01888	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IANEGIEI_01889	3.33e-92	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IANEGIEI_01890	6.55e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IANEGIEI_01891	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IANEGIEI_01892	1.3e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IANEGIEI_01893	1.1e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IANEGIEI_01894	3.12e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IANEGIEI_01895	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IANEGIEI_01896	4.74e-221	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IANEGIEI_01897	5.35e-148	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IANEGIEI_01898	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IANEGIEI_01899	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IANEGIEI_01900	5.8e-223	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
IANEGIEI_01901	4.93e-85	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IANEGIEI_01903	2.17e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
IANEGIEI_01904	1.1e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01905	6.29e-285	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IANEGIEI_01906	2.53e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IANEGIEI_01907	1.2e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IANEGIEI_01908	3.27e-108	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IANEGIEI_01909	1.24e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IANEGIEI_01911	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IANEGIEI_01913	1.91e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IANEGIEI_01914	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IANEGIEI_01915	1.15e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IANEGIEI_01916	1.11e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IANEGIEI_01917	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IANEGIEI_01918	1.34e-24	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IANEGIEI_01919	9.81e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IANEGIEI_01920	1.33e-188	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IANEGIEI_01921	5.75e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IANEGIEI_01922	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IANEGIEI_01923	9.65e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IANEGIEI_01924	7.95e-53	-	-	-	L	-	-	-	Transposase
IANEGIEI_01925	6.77e-216	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IANEGIEI_01926	1.57e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IANEGIEI_01927	4.43e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IANEGIEI_01928	3.13e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IANEGIEI_01929	1.27e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IANEGIEI_01930	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IANEGIEI_01931	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IANEGIEI_01933	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IANEGIEI_01934	2.68e-161	-	-	-	F	-	-	-	NUDIX domain
IANEGIEI_01935	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
IANEGIEI_01936	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IANEGIEI_01937	2.31e-125	-	-	-	S	-	-	-	Pfam:DUF3816
IANEGIEI_01938	7.8e-181	-	-	-	G	-	-	-	MucBP domain
IANEGIEI_01939	7.22e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IANEGIEI_01940	3.65e-207	-	-	-	EG	-	-	-	EamA-like transporter family
IANEGIEI_01941	1.95e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IANEGIEI_01944	7.78e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IANEGIEI_01945	6.96e-83	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
IANEGIEI_01946	3.47e-215	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IANEGIEI_01947	2e-30	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
IANEGIEI_01948	7.34e-50	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IANEGIEI_01950	2.84e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IANEGIEI_01951	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IANEGIEI_01952	2.71e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IANEGIEI_01953	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IANEGIEI_01954	5.03e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IANEGIEI_01955	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IANEGIEI_01956	3.15e-147	-	-	-	-	-	-	-	-
IANEGIEI_01959	3.09e-208	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IANEGIEI_01960	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IANEGIEI_01961	2.05e-201	-	-	-	D	-	-	-	nuclear chromosome segregation
IANEGIEI_01962	1.79e-281	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IANEGIEI_01963	8.34e-29	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
IANEGIEI_01964	1.44e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IANEGIEI_01965	2.24e-140	-	-	-	S	-	-	-	VIT family
IANEGIEI_01966	9.24e-151	-	-	-	S	-	-	-	membrane
IANEGIEI_01967	1.25e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IANEGIEI_01968	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IANEGIEI_01969	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IANEGIEI_01970	7.5e-159	-	-	-	S	-	-	-	Putative threonine/serine exporter
IANEGIEI_01971	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IANEGIEI_01972	2.47e-146	-	-	-	I	-	-	-	phosphatase
IANEGIEI_01973	4.2e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IANEGIEI_01975	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IANEGIEI_01976	6.66e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IANEGIEI_01982	1.48e-12	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANEGIEI_01983	7.2e-92	-	-	-	IQ	-	-	-	reductase
IANEGIEI_01984	8.33e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IANEGIEI_01985	1.37e-68	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IANEGIEI_01986	1.95e-92	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
IANEGIEI_01987	1.34e-70	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
IANEGIEI_01988	8.45e-27	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
IANEGIEI_01989	8.62e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
IANEGIEI_01990	2.8e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
IANEGIEI_01991	2.65e-245	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IANEGIEI_01993	3.66e-277	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IANEGIEI_01995	5.15e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IANEGIEI_01996	6.9e-126	-	-	-	K	-	-	-	Virulence activator alpha C-term
IANEGIEI_01997	1.37e-103	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IANEGIEI_01998	3.23e-21	-	-	-	S	-	-	-	SNARE associated Golgi protein
IANEGIEI_01999	3.72e-302	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IANEGIEI_02000	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IANEGIEI_02002	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IANEGIEI_02003	2.8e-232	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
IANEGIEI_02004	2.69e-190	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
IANEGIEI_02005	1.56e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IANEGIEI_02006	1.39e-296	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IANEGIEI_02007	2.75e-167	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
IANEGIEI_02008	4.13e-304	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
IANEGIEI_02009	8.05e-157	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
IANEGIEI_02010	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IANEGIEI_02011	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IANEGIEI_02012	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IANEGIEI_02013	2.14e-147	-	-	-	K	-	-	-	Transcriptional regulator
IANEGIEI_02015	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
IANEGIEI_02016	4.09e-269	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
IANEGIEI_02018	2.33e-269	-	-	-	S	-	-	-	peptidoglycan catabolic process
IANEGIEI_02019	8.39e-37	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
IANEGIEI_02024	9.37e-34	-	-	-	S	-	-	-	GDSL-like Lipase/Acylhydrolase
IANEGIEI_02027	4.38e-109	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	Intracellular protease