ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NKIHKOBL_00001 1.11e-114 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_00002 2.38e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_00003 1.67e-49 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_00004 4.04e-86 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKIHKOBL_00005 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NKIHKOBL_00006 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
NKIHKOBL_00007 5.7e-124 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKIHKOBL_00008 1.46e-120 - - - S - - - ECF transporter, substrate-specific component
NKIHKOBL_00009 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NKIHKOBL_00010 4.64e-159 blpT - - - - - - -
NKIHKOBL_00011 9.35e-36 blpT - - - - - - -
NKIHKOBL_00012 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
NKIHKOBL_00015 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NKIHKOBL_00016 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NKIHKOBL_00017 2.69e-56 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NKIHKOBL_00018 6.61e-179 cppA - - E - - - CppA N-terminal
NKIHKOBL_00019 4.14e-235 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
NKIHKOBL_00020 2.51e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00021 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NKIHKOBL_00022 1.96e-113 - - - D - - - nuclear chromosome segregation
NKIHKOBL_00023 5.58e-60 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NKIHKOBL_00024 9.32e-112 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKIHKOBL_00025 1.98e-189 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
NKIHKOBL_00026 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
NKIHKOBL_00027 2.53e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKIHKOBL_00029 1.04e-194 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NKIHKOBL_00030 2.53e-208 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_00031 1.61e-168 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00032 1.48e-13 - - - S - - - Protein of unknown function (DUF4059)
NKIHKOBL_00033 4.78e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NKIHKOBL_00034 9.01e-121 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NKIHKOBL_00035 7.91e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKIHKOBL_00036 7.98e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NKIHKOBL_00037 1.51e-236 ytqA - - S ko:K07139 - ko00000 radical SAM protein
NKIHKOBL_00038 9e-127 mraW1 - - J - - - (SAM)-dependent
NKIHKOBL_00040 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
NKIHKOBL_00041 1.29e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00042 2.02e-304 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
NKIHKOBL_00043 6.98e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NKIHKOBL_00046 7.54e-99 XK27_03180 - - T - - - universal stress protein
NKIHKOBL_00047 2.61e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NKIHKOBL_00048 6.34e-182 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NKIHKOBL_00049 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
NKIHKOBL_00050 3.85e-198 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NKIHKOBL_00051 1.38e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKIHKOBL_00052 5.44e-98 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKIHKOBL_00053 1.06e-187 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKIHKOBL_00054 6.32e-42 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
NKIHKOBL_00055 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKIHKOBL_00056 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NKIHKOBL_00057 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKIHKOBL_00058 1.94e-76 - - - - - - - -
NKIHKOBL_00059 3.34e-194 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKIHKOBL_00060 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NKIHKOBL_00061 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NKIHKOBL_00062 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NKIHKOBL_00063 5.51e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKIHKOBL_00064 8.21e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NKIHKOBL_00065 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NKIHKOBL_00066 2.78e-179 XK27_06665 - - Q - - - Methyltransferase domain protein
NKIHKOBL_00067 4.36e-263 ylbM - - S - - - Belongs to the UPF0348 family
NKIHKOBL_00068 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
NKIHKOBL_00069 3.82e-140 - - - - - - - -
NKIHKOBL_00070 1.93e-67 - - - S - - - CD20-like family
NKIHKOBL_00071 4.47e-13 - - - - - - - -
NKIHKOBL_00072 6.15e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NKIHKOBL_00073 1.5e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00074 7.69e-232 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NKIHKOBL_00075 8.46e-197 ytmP - - M - - - Phosphotransferase
NKIHKOBL_00076 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NKIHKOBL_00078 9.59e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
NKIHKOBL_00079 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
NKIHKOBL_00080 8.66e-83 XK27_02560 - - S - - - cog cog2151
NKIHKOBL_00081 8.12e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
NKIHKOBL_00082 2.17e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NKIHKOBL_00083 6.01e-167 - - - K - - - transcriptional regulator, MerR family
NKIHKOBL_00084 6.16e-38 - - - L - - - transposase activity
NKIHKOBL_00085 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKIHKOBL_00087 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NKIHKOBL_00088 1.25e-74 - - - - - - - -
NKIHKOBL_00089 9.49e-57 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
NKIHKOBL_00090 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKIHKOBL_00091 2.03e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
NKIHKOBL_00092 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKIHKOBL_00093 2.28e-172 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NKIHKOBL_00094 1.25e-127 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
NKIHKOBL_00095 1.66e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NKIHKOBL_00096 6.12e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NKIHKOBL_00097 4.28e-97 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
NKIHKOBL_00098 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NKIHKOBL_00099 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
NKIHKOBL_00100 9.64e-248 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NKIHKOBL_00101 8.58e-149 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_00102 3.24e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_00103 2.74e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00104 9.46e-200 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NKIHKOBL_00108 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NKIHKOBL_00109 1.63e-155 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
NKIHKOBL_00110 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NKIHKOBL_00111 1.09e-257 yjbB - - G - - - Permeases of the major facilitator superfamily
NKIHKOBL_00112 5.28e-203 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
NKIHKOBL_00113 4.57e-129 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
NKIHKOBL_00114 7.5e-83 yjqA - - S - - - Bacterial PH domain
NKIHKOBL_00115 6.14e-205 corA - - P - - - CorA-like protein
NKIHKOBL_00116 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NKIHKOBL_00117 4.12e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NKIHKOBL_00118 2.91e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
NKIHKOBL_00119 6.52e-31 nodB3 - - G - - - polysaccharide deacetylase
NKIHKOBL_00120 1.33e-112 nodB3 - - G - - - polysaccharide deacetylase
NKIHKOBL_00121 1.76e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NKIHKOBL_00122 1.38e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NKIHKOBL_00123 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NKIHKOBL_00124 2.13e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKIHKOBL_00125 2.39e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
NKIHKOBL_00126 1.06e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
NKIHKOBL_00127 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NKIHKOBL_00128 2.38e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
NKIHKOBL_00129 3.26e-110 ccl - - S - - - cog cog4708
NKIHKOBL_00130 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NKIHKOBL_00131 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKIHKOBL_00132 2.2e-68 - - - L - - - Transposase
NKIHKOBL_00133 1.22e-97 - - - S - - - QueT transporter
NKIHKOBL_00134 5.11e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NKIHKOBL_00136 5.38e-219 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
NKIHKOBL_00137 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NKIHKOBL_00138 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
NKIHKOBL_00139 2.35e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NKIHKOBL_00140 0.0 ydaO - - E - - - amino acid
NKIHKOBL_00141 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
NKIHKOBL_00142 1.29e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKIHKOBL_00143 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00144 1.05e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKIHKOBL_00145 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NKIHKOBL_00146 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NKIHKOBL_00147 1.38e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NKIHKOBL_00148 2e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
NKIHKOBL_00149 1.79e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
NKIHKOBL_00150 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
NKIHKOBL_00151 1.85e-05 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
NKIHKOBL_00152 9.3e-29 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
NKIHKOBL_00153 8.98e-71 XK27_08050 - - O - - - stress-induced mitochondrial fusion
NKIHKOBL_00154 9.31e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
NKIHKOBL_00155 7.31e-125 - - - GK - - - ROK family
NKIHKOBL_00156 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKIHKOBL_00157 5.63e-136 - - - M - - - Acetyltransferase (GNAT) domain
NKIHKOBL_00158 2.15e-280 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKIHKOBL_00159 7.41e-68 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
NKIHKOBL_00160 2.92e-78 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NKIHKOBL_00162 5.26e-77 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
NKIHKOBL_00163 4.46e-151 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
NKIHKOBL_00164 1.07e-141 - - - S - - - IA, variant 1
NKIHKOBL_00165 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKIHKOBL_00166 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NKIHKOBL_00167 7.46e-149 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
NKIHKOBL_00168 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NKIHKOBL_00169 1.72e-209 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_00170 7.78e-69 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_00171 1.22e-140 csn2 - - S ko:K19137 - ko00000,ko02048 CRISPR-associated protein (Cas_Csn2)
NKIHKOBL_00173 1.61e-197 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
NKIHKOBL_00175 1.17e-40 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
NKIHKOBL_00176 1.25e-85 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
NKIHKOBL_00179 2.22e-173 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NKIHKOBL_00180 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
NKIHKOBL_00181 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NKIHKOBL_00182 5.28e-24 XK27_00735 - - - - - - -
NKIHKOBL_00183 1.44e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00184 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
NKIHKOBL_00185 5.12e-42 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NKIHKOBL_00186 5.75e-99 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NKIHKOBL_00187 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NKIHKOBL_00188 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
NKIHKOBL_00189 6.76e-185 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NKIHKOBL_00190 9.25e-177 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
NKIHKOBL_00191 3.22e-268 arcT - - E - - - Aminotransferase
NKIHKOBL_00192 6.03e-177 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NKIHKOBL_00193 1.9e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NKIHKOBL_00194 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NKIHKOBL_00195 3.03e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NKIHKOBL_00196 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
NKIHKOBL_00197 0.0 - - - M - - - Psort location CytoplasmicMembrane, score
NKIHKOBL_00198 8.57e-218 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
NKIHKOBL_00199 2.59e-313 - - - - - - - -
NKIHKOBL_00200 7.75e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NKIHKOBL_00201 2.92e-162 - - - S - - - Glycosyl transferase family 2
NKIHKOBL_00202 3.81e-64 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
NKIHKOBL_00203 4.01e-281 rgpX3 - - S - - - polysaccharide biosynthetic process
NKIHKOBL_00204 1.13e-249 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
NKIHKOBL_00205 5.93e-288 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
NKIHKOBL_00206 3.16e-231 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NKIHKOBL_00207 3.89e-184 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NKIHKOBL_00208 2.09e-287 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NKIHKOBL_00209 5.39e-251 rgpE - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 COG0463 Glycosyltransferases involved in cell wall biogenesis
NKIHKOBL_00210 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
NKIHKOBL_00211 1.61e-154 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NKIHKOBL_00212 1.83e-166 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
NKIHKOBL_00213 1.35e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NKIHKOBL_00214 1.46e-77 XK27_04120 - - S - - - Putative amino acid metabolism
NKIHKOBL_00215 4.54e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NKIHKOBL_00216 2.07e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKIHKOBL_00217 5.5e-134 yjbK - - S - - - Adenylate cyclase
NKIHKOBL_00218 1.24e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
NKIHKOBL_00219 1.56e-193 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKIHKOBL_00220 4.44e-221 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NKIHKOBL_00221 1.15e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NKIHKOBL_00222 6.82e-25 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_00223 5.73e-33 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_00224 5.98e-47 - - - K - - - sequence-specific DNA binding
NKIHKOBL_00226 0.0 - - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
NKIHKOBL_00227 1.97e-295 spaC2 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
NKIHKOBL_00228 9.08e-237 - - - EGP - - - Major Facilitator Superfamily
NKIHKOBL_00229 4.95e-33 - 3.6.4.12 - - ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 -
NKIHKOBL_00230 4.37e-119 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Divergent AAA domain protein
NKIHKOBL_00231 4.74e-286 int - - L - - - Belongs to the 'phage' integrase family
NKIHKOBL_00232 1.67e-51 - - - S - - - Helix-turn-helix domain
NKIHKOBL_00233 4.77e-220 - - - - - - - -
NKIHKOBL_00235 4.04e-95 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
NKIHKOBL_00236 6.53e-118 - - - L ko:K07498 - ko00000 Transposase
NKIHKOBL_00237 3.89e-285 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
NKIHKOBL_00238 1.76e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
NKIHKOBL_00239 1.6e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NKIHKOBL_00240 4.76e-50 ais - - G - - - alpha-ribazole phosphatase activity
NKIHKOBL_00241 4.65e-186 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NKIHKOBL_00242 5.34e-134 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
NKIHKOBL_00243 4.82e-254 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NKIHKOBL_00244 2.93e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKIHKOBL_00245 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NKIHKOBL_00246 4.85e-258 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NKIHKOBL_00247 1.02e-176 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NKIHKOBL_00248 3.02e-176 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
NKIHKOBL_00249 7.01e-81 hmpT - - S - - - membrane
NKIHKOBL_00255 9.95e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NKIHKOBL_00256 9.03e-141 - - - S - - - Domain of unknown function (DUF1803)
NKIHKOBL_00257 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NKIHKOBL_00258 4.96e-173 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NKIHKOBL_00259 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKIHKOBL_00260 9.23e-246 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NKIHKOBL_00261 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NKIHKOBL_00262 5.93e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
NKIHKOBL_00263 4.99e-180 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
NKIHKOBL_00264 4.43e-95 XK27_02735 - - K - - - Transcriptional regulator, MarR family
NKIHKOBL_00265 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKIHKOBL_00266 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKIHKOBL_00267 1.31e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
NKIHKOBL_00268 1.35e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NKIHKOBL_00269 8.26e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NKIHKOBL_00270 2.6e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKIHKOBL_00271 2.48e-87 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NKIHKOBL_00272 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NKIHKOBL_00273 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NKIHKOBL_00274 1.4e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NKIHKOBL_00275 3.26e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NKIHKOBL_00276 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NKIHKOBL_00277 4.67e-162 - - - L ko:K07498 - ko00000 Transposase
NKIHKOBL_00279 0.0 - - - S - - - Protein of unknown function (DUF3114)
NKIHKOBL_00280 1.78e-68 - - - K - - - Acetyltransferase GNAT Family
NKIHKOBL_00281 1.23e-249 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 (ABC) transporter
NKIHKOBL_00282 5.01e-93 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
NKIHKOBL_00283 1.44e-106 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
NKIHKOBL_00284 1.71e-143 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NKIHKOBL_00285 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKIHKOBL_00286 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NKIHKOBL_00287 1.76e-164 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
NKIHKOBL_00288 1.24e-121 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKIHKOBL_00289 3.14e-177 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00290 2.63e-212 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
NKIHKOBL_00291 1.46e-132 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_00292 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NKIHKOBL_00293 1.2e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
NKIHKOBL_00294 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NKIHKOBL_00295 6.62e-157 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NKIHKOBL_00296 1.03e-38 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NKIHKOBL_00297 2.23e-131 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NKIHKOBL_00299 8.38e-188 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NKIHKOBL_00300 4.06e-127 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
NKIHKOBL_00301 1.4e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKIHKOBL_00302 1.2e-245 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_00303 2.48e-171 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NKIHKOBL_00304 2.94e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00307 3.05e-210 yocS - - S ko:K03453 - ko00000 Transporter
NKIHKOBL_00308 9.95e-108 - - - F - - - cytidine deaminase activity
NKIHKOBL_00309 3.95e-147 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
NKIHKOBL_00310 2.89e-194 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00313 7.82e-128 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
NKIHKOBL_00314 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NKIHKOBL_00315 6.05e-171 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NKIHKOBL_00316 1.2e-215 - - - T - - - Histidine kinase
NKIHKOBL_00317 2.13e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKIHKOBL_00318 2.47e-100 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NKIHKOBL_00319 4.96e-86 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
NKIHKOBL_00320 1.48e-153 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NKIHKOBL_00321 0.0 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NKIHKOBL_00322 5.51e-239 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKIHKOBL_00323 4.2e-301 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NKIHKOBL_00324 2.22e-85 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKIHKOBL_00325 3.23e-75 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKIHKOBL_00326 5.5e-34 csbD - - K - - - CsbD-like
NKIHKOBL_00327 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
NKIHKOBL_00328 3.47e-142 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
NKIHKOBL_00329 1.37e-192 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NKIHKOBL_00330 2.96e-100 ywnA_2 - - K - - - Transcriptional regulator
NKIHKOBL_00331 1.07e-202 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
NKIHKOBL_00332 1.19e-294 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKIHKOBL_00333 2.35e-142 ydgI - - C - - - Nitroreductase
NKIHKOBL_00334 1.33e-136 - - - S - - - Protein of unknown function (DUF1275)
NKIHKOBL_00335 1.23e-06 - - - S - - - Protein of unknown function (DUF1275)
NKIHKOBL_00336 2.73e-204 yvgN - - C - - - reductase
NKIHKOBL_00337 7.53e-229 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NKIHKOBL_00338 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
NKIHKOBL_00340 1.58e-50 BP1961 - - P - - - nitric oxide dioxygenase activity
NKIHKOBL_00341 1.79e-70 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NKIHKOBL_00342 4.2e-86 - - - S - - - Signal peptide protein, YSIRK family
NKIHKOBL_00343 8.65e-81 - - - - - - - -
NKIHKOBL_00344 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKIHKOBL_00345 1.14e-217 - - - - - - - -
NKIHKOBL_00346 1.08e-14 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
NKIHKOBL_00348 4.88e-140 - - - E - - - LysE type translocator
NKIHKOBL_00349 6.23e-11 - - - - - - - -
NKIHKOBL_00350 1.96e-12 - - - - - - - -
NKIHKOBL_00351 0.0 - - - M - - - family 8
NKIHKOBL_00352 9.49e-223 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NKIHKOBL_00353 3.81e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00354 1.31e-195 - - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MatE
NKIHKOBL_00355 2.93e-10 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
NKIHKOBL_00356 9.95e-138 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
NKIHKOBL_00357 6.25e-227 - - - EGP - - - Major Facilitator Superfamily
NKIHKOBL_00358 0.0 - - - I - - - radical SAM domain protein
NKIHKOBL_00360 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
NKIHKOBL_00361 1.88e-194 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00362 8.81e-114 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_00364 2.36e-110 - - - - - - - -
NKIHKOBL_00365 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
NKIHKOBL_00366 2.27e-293 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NKIHKOBL_00367 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
NKIHKOBL_00368 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
NKIHKOBL_00369 2.8e-256 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NKIHKOBL_00370 6.03e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NKIHKOBL_00371 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
NKIHKOBL_00372 1.15e-282 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKIHKOBL_00373 1.4e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NKIHKOBL_00374 6.92e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00375 1.18e-34 - - - L ko:K07497 - ko00000 transposition
NKIHKOBL_00376 1.38e-276 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
NKIHKOBL_00377 8.99e-24 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
NKIHKOBL_00378 4.19e-124 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00379 1.91e-47 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00380 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NKIHKOBL_00381 1.03e-80 - - - L - - - Transposase
NKIHKOBL_00382 2.67e-186 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00383 1.58e-39 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00384 1.17e-147 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00385 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NKIHKOBL_00386 8.16e-241 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NKIHKOBL_00387 5.68e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NKIHKOBL_00388 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKIHKOBL_00391 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKIHKOBL_00392 4.58e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_00393 6.28e-154 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
NKIHKOBL_00394 6.62e-137 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NKIHKOBL_00395 1.07e-226 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NKIHKOBL_00396 1.05e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NKIHKOBL_00397 1.1e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKIHKOBL_00398 4.26e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKIHKOBL_00399 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKIHKOBL_00400 2.77e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
NKIHKOBL_00401 8.75e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NKIHKOBL_00402 3.65e-308 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NKIHKOBL_00403 6.12e-192 XK27_02985 - - S - - - overlaps another CDS with the same product name
NKIHKOBL_00404 7.63e-185 - - - S - - - overlaps another CDS with the same product name
NKIHKOBL_00405 3.45e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
NKIHKOBL_00406 5.01e-160 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00407 6.44e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
NKIHKOBL_00408 6.58e-213 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
NKIHKOBL_00409 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
NKIHKOBL_00410 1.67e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
NKIHKOBL_00411 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NKIHKOBL_00412 1.38e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NKIHKOBL_00413 1.53e-100 sptS - - T - - - Histidine kinase
NKIHKOBL_00414 6.54e-58 - - - K - - - Acetyltransferase (GNAT) family
NKIHKOBL_00415 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00416 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00417 4.4e-101 - - - K - - - DNA-binding transcription factor activity
NKIHKOBL_00418 3.88e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NKIHKOBL_00419 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NKIHKOBL_00420 1.29e-73 nadR - - H - - - adenylyltransferase
NKIHKOBL_00421 1.16e-175 nadR - - H - - - adenylyltransferase
NKIHKOBL_00422 1.44e-177 - - - F - - - AdP-ribose pyrophosphatase
NKIHKOBL_00423 2.24e-27 - - - S - - - Short repeat of unknown function (DUF308)
NKIHKOBL_00424 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00425 7.9e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NKIHKOBL_00426 6.34e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NKIHKOBL_00427 4.81e-96 - - - S - - - EDD domain protein, DegV family
NKIHKOBL_00428 3.86e-78 - - - S - - - EDD domain protein, DegV family
NKIHKOBL_00429 2.74e-84 WQ51_03320 - - S - - - cog cog4835
NKIHKOBL_00430 5.47e-168 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NKIHKOBL_00431 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NKIHKOBL_00432 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NKIHKOBL_00433 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
NKIHKOBL_00434 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NKIHKOBL_00435 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NKIHKOBL_00436 6.04e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKIHKOBL_00437 1.8e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NKIHKOBL_00438 3.47e-06 - - - - - - - -
NKIHKOBL_00439 9.28e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NKIHKOBL_00440 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKIHKOBL_00441 7.12e-302 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKIHKOBL_00442 3.88e-101 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NKIHKOBL_00443 7.23e-209 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NKIHKOBL_00444 7.9e-165 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
NKIHKOBL_00445 8.72e-111 - - - L ko:K07485 - ko00000 Transposase
NKIHKOBL_00446 3.13e-311 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NKIHKOBL_00447 1.97e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
NKIHKOBL_00448 5.61e-228 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
NKIHKOBL_00449 4.63e-236 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
NKIHKOBL_00450 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NKIHKOBL_00451 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NKIHKOBL_00452 5.32e-209 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NKIHKOBL_00454 1.06e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NKIHKOBL_00455 1.81e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NKIHKOBL_00456 2.13e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
NKIHKOBL_00457 9.39e-98 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NKIHKOBL_00458 5.36e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NKIHKOBL_00459 5.03e-183 - - - S - - - Macro domain protein
NKIHKOBL_00460 1.78e-10 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
NKIHKOBL_00461 3.38e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
NKIHKOBL_00463 5.82e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NKIHKOBL_00464 7.8e-38 yqgQ - - S - - - protein conserved in bacteria
NKIHKOBL_00465 1.76e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NKIHKOBL_00466 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NKIHKOBL_00467 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
NKIHKOBL_00468 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NKIHKOBL_00469 3.84e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKIHKOBL_00470 1.94e-235 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NKIHKOBL_00471 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NKIHKOBL_00472 2.64e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKIHKOBL_00473 9.77e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NKIHKOBL_00474 1.79e-125 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
NKIHKOBL_00475 1.8e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
NKIHKOBL_00476 4.13e-185 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
NKIHKOBL_00477 2.95e-186 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
NKIHKOBL_00478 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NKIHKOBL_00479 1.93e-12 - - - - - - - -
NKIHKOBL_00481 4.37e-119 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
NKIHKOBL_00482 2.9e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NKIHKOBL_00483 6.31e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKIHKOBL_00484 1.69e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NKIHKOBL_00485 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NKIHKOBL_00486 1.96e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NKIHKOBL_00487 1.07e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKIHKOBL_00488 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKIHKOBL_00491 2.66e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
NKIHKOBL_00492 1.03e-304 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKIHKOBL_00494 1.46e-112 - - - S - - - ECF-type riboflavin transporter, S component
NKIHKOBL_00495 4.85e-56 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
NKIHKOBL_00496 4.44e-108 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
NKIHKOBL_00497 3.43e-107 - - - S - - - ECF-type riboflavin transporter, S component
NKIHKOBL_00498 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
NKIHKOBL_00499 0.0 noxE - - P - - - NADH oxidase
NKIHKOBL_00500 2.06e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NKIHKOBL_00501 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKIHKOBL_00502 4.41e-169 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
NKIHKOBL_00503 1.88e-67 ywkD - - E ko:K08234 - ko00000 COG0346 LactoylglutaTHIone lyase and related lyases
NKIHKOBL_00504 1.39e-211 ypuA - - S - - - secreted protein
NKIHKOBL_00505 1.1e-36 - - - L - - - Transposase (IS116 IS110 IS902 family)
NKIHKOBL_00506 2.35e-50 - - - L - - - Transposase (IS116 IS110 IS902 family)
NKIHKOBL_00508 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKIHKOBL_00509 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKIHKOBL_00510 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NKIHKOBL_00511 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKIHKOBL_00512 4.25e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NKIHKOBL_00513 7.22e-283 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
NKIHKOBL_00514 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
NKIHKOBL_00515 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NKIHKOBL_00518 1.17e-122 ywlG - - S - - - Belongs to the UPF0340 family
NKIHKOBL_00519 6.51e-114 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
NKIHKOBL_00520 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
NKIHKOBL_00521 3.49e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
NKIHKOBL_00522 4.14e-87 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKIHKOBL_00523 4.39e-90 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKIHKOBL_00524 3.67e-49 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKIHKOBL_00525 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NKIHKOBL_00526 9.31e-84 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
NKIHKOBL_00527 9.16e-161 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NKIHKOBL_00528 5.74e-86 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NKIHKOBL_00529 3.04e-48 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
NKIHKOBL_00530 4.79e-77 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NKIHKOBL_00531 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NKIHKOBL_00532 1.31e-286 norN - - V - - - Mate efflux family protein
NKIHKOBL_00533 1.87e-76 asp - - S - - - cog cog1302
NKIHKOBL_00534 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NKIHKOBL_00535 1.57e-11 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NKIHKOBL_00536 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NKIHKOBL_00537 1.83e-10 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NKIHKOBL_00538 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NKIHKOBL_00539 2.89e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NKIHKOBL_00540 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKIHKOBL_00541 2.34e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKIHKOBL_00542 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKIHKOBL_00543 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKIHKOBL_00544 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKIHKOBL_00545 3.93e-91 - - - S - - - cog cog4699
NKIHKOBL_00546 3.13e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKIHKOBL_00547 3.69e-195 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NKIHKOBL_00548 1.06e-60 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NKIHKOBL_00549 1.03e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
NKIHKOBL_00550 1.28e-21 - - - NU - - - Type II secretory pathway pseudopilin
NKIHKOBL_00551 2.56e-94 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
NKIHKOBL_00552 5.13e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NKIHKOBL_00553 2.04e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NKIHKOBL_00554 1.89e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKIHKOBL_00555 4.3e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NKIHKOBL_00556 1.2e-85 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NKIHKOBL_00558 1.6e-141 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
NKIHKOBL_00559 4.76e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKIHKOBL_00560 3.7e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NKIHKOBL_00562 3.48e-73 ytpP - - CO - - - Thioredoxin
NKIHKOBL_00563 5.51e-147 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKIHKOBL_00564 3.62e-245 yeeE - - S ko:K07112 - ko00000 Sulphur transport
NKIHKOBL_00565 2.25e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
NKIHKOBL_00566 3.13e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKIHKOBL_00567 1.7e-117 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NKIHKOBL_00570 4.03e-202 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
NKIHKOBL_00571 1.53e-85 - - - S ko:K07025 - ko00000 phosphatase activity
NKIHKOBL_00572 9.35e-64 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
NKIHKOBL_00573 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NKIHKOBL_00574 1.34e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NKIHKOBL_00575 2.82e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKIHKOBL_00576 2.39e-154 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NKIHKOBL_00577 7.92e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NKIHKOBL_00578 5.94e-238 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NKIHKOBL_00579 9.39e-83 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NKIHKOBL_00580 4.96e-82 nirC_1 - - P - - - Formate nitrite transporter
NKIHKOBL_00581 3.86e-182 XK27_09615 - - C ko:K19784 - ko00000 reductase
NKIHKOBL_00582 4.64e-77 XK27_09615 - - C ko:K19784 - ko00000 reductase
NKIHKOBL_00583 2.97e-100 - - - S - - - reductase
NKIHKOBL_00584 1.24e-26 XK27_09620 - - S - - - FMN reductase (NADPH) activity
NKIHKOBL_00585 2.98e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NKIHKOBL_00586 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NKIHKOBL_00587 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
NKIHKOBL_00588 7.36e-75 - - - S - - - Mitochondrial biogenesis AIM24
NKIHKOBL_00589 9.62e-116 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NKIHKOBL_00590 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
NKIHKOBL_00591 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NKIHKOBL_00592 1.66e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NKIHKOBL_00593 1.82e-97 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
NKIHKOBL_00594 3.66e-83 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
NKIHKOBL_00595 1.75e-24 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NKIHKOBL_00596 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKIHKOBL_00597 3.19e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NKIHKOBL_00598 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
NKIHKOBL_00599 8.28e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NKIHKOBL_00600 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKIHKOBL_00601 7.21e-239 jag - - S ko:K06346 - ko00000 RNA-binding protein
NKIHKOBL_00602 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
NKIHKOBL_00603 1.4e-44 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00604 1.09e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NKIHKOBL_00605 4.98e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKIHKOBL_00606 2.07e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
NKIHKOBL_00607 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKIHKOBL_00608 3.08e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NKIHKOBL_00609 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00610 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00611 1.1e-128 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
NKIHKOBL_00612 4.29e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
NKIHKOBL_00613 1.45e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKIHKOBL_00614 1.2e-140 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NKIHKOBL_00615 3.18e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NKIHKOBL_00616 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKIHKOBL_00617 1.16e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NKIHKOBL_00618 1.3e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NKIHKOBL_00619 7.83e-197 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
NKIHKOBL_00620 2.51e-236 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
NKIHKOBL_00621 5.61e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NKIHKOBL_00622 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
NKIHKOBL_00623 4.66e-296 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
NKIHKOBL_00624 2.32e-43 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00625 3.46e-204 - - - S - - - CHAP domain
NKIHKOBL_00626 8.2e-306 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NKIHKOBL_00627 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKIHKOBL_00628 1.03e-261 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NKIHKOBL_00629 1.69e-181 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
NKIHKOBL_00630 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NKIHKOBL_00631 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NKIHKOBL_00632 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NKIHKOBL_00633 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NKIHKOBL_00634 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NKIHKOBL_00635 1.06e-43 - - - S - - - Protein of unknown function (DUF3021)
NKIHKOBL_00636 2.17e-81 - - - KT - - - phosphorelay signal transduction system
NKIHKOBL_00638 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKIHKOBL_00640 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NKIHKOBL_00641 1.89e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
NKIHKOBL_00642 2.06e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NKIHKOBL_00643 4.62e-255 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKIHKOBL_00644 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NKIHKOBL_00645 1.15e-12 - - - L ko:K07497 - ko00000 transposition
NKIHKOBL_00646 3.94e-35 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00647 1.99e-45 - - - - - - - -
NKIHKOBL_00649 5.05e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NKIHKOBL_00650 1.26e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NKIHKOBL_00651 4.48e-277 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
NKIHKOBL_00652 1.74e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKIHKOBL_00653 0.0 covS - - T - - - Histidine kinase
NKIHKOBL_00654 3.82e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKIHKOBL_00655 1.14e-118 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NKIHKOBL_00656 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
NKIHKOBL_00657 1e-309 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
NKIHKOBL_00658 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NKIHKOBL_00659 1.65e-14 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
NKIHKOBL_00660 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKIHKOBL_00661 2.29e-187 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NKIHKOBL_00662 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00663 5.41e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NKIHKOBL_00664 5.95e-202 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
NKIHKOBL_00665 7.28e-268 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NKIHKOBL_00666 1.77e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_00667 2.17e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NKIHKOBL_00668 1.96e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
NKIHKOBL_00669 1.48e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
NKIHKOBL_00670 6.08e-112 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NKIHKOBL_00671 1.26e-212 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NKIHKOBL_00672 3.16e-186 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
NKIHKOBL_00673 4.24e-30 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 carboxypeptidase activity
NKIHKOBL_00674 2.86e-127 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NKIHKOBL_00676 5e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NKIHKOBL_00677 1.73e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKIHKOBL_00678 3.55e-109 - - - S - - - Putative small multi-drug export protein
NKIHKOBL_00679 2.83e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NKIHKOBL_00680 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NKIHKOBL_00681 1.71e-193 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKIHKOBL_00682 3.96e-40 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKIHKOBL_00683 1.38e-295 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKIHKOBL_00684 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NKIHKOBL_00685 9.44e-186 - - - S - - - SseB protein N-terminal domain
NKIHKOBL_00686 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
NKIHKOBL_00687 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NKIHKOBL_00688 2.1e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NKIHKOBL_00691 1.23e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKIHKOBL_00692 8.14e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NKIHKOBL_00693 1.1e-199 yitS - - S - - - DegV family
NKIHKOBL_00694 1.22e-42 - - - K - - - helix-turn-helix
NKIHKOBL_00695 4e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKIHKOBL_00696 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKIHKOBL_00697 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NKIHKOBL_00698 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NKIHKOBL_00699 1.04e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NKIHKOBL_00700 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NKIHKOBL_00701 1.99e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
NKIHKOBL_00702 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKIHKOBL_00703 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKIHKOBL_00704 2.72e-56 ysdA - - L - - - Membrane
NKIHKOBL_00705 7.51e-242 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NKIHKOBL_00706 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKIHKOBL_00707 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NKIHKOBL_00708 3.83e-229 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
NKIHKOBL_00710 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKIHKOBL_00711 2.85e-122 ypmS - - S - - - Protein conserved in bacteria
NKIHKOBL_00712 4.24e-185 ypmR - - E - - - lipolytic protein G-D-S-L family
NKIHKOBL_00713 1.18e-190 WQ51_01275 - - S - - - DegV family
NKIHKOBL_00714 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NKIHKOBL_00715 1.72e-94 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NKIHKOBL_00716 2.83e-203 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NKIHKOBL_00717 8.12e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NKIHKOBL_00718 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
NKIHKOBL_00719 9.08e-314 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKIHKOBL_00722 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKIHKOBL_00723 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
NKIHKOBL_00724 5.91e-234 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKIHKOBL_00725 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKIHKOBL_00726 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
NKIHKOBL_00727 4.46e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKIHKOBL_00728 4.43e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NKIHKOBL_00729 1.15e-152 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
NKIHKOBL_00730 5.77e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKIHKOBL_00731 0.0 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NKIHKOBL_00732 1.48e-65 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NKIHKOBL_00733 7.31e-81 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NKIHKOBL_00734 8.59e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NKIHKOBL_00735 9.32e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NKIHKOBL_00736 3.32e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NKIHKOBL_00737 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NKIHKOBL_00738 2.16e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NKIHKOBL_00739 1.98e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NKIHKOBL_00740 5.26e-234 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NKIHKOBL_00741 1.23e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKIHKOBL_00745 1.16e-57 - - - - - - - -
NKIHKOBL_00746 5.62e-75 WQ51_06355 - - S - - - TM2 domain
NKIHKOBL_00747 1.17e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NKIHKOBL_00748 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKIHKOBL_00749 6.28e-35 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
NKIHKOBL_00750 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NKIHKOBL_00751 1.17e-110 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
NKIHKOBL_00752 6.76e-73 cof - - Q - - - phosphatase activity
NKIHKOBL_00753 1.89e-47 cof - - Q - - - phosphatase activity
NKIHKOBL_00754 6.57e-176 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
NKIHKOBL_00755 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NKIHKOBL_00756 1.73e-53 napB - - K - - - transcriptional
NKIHKOBL_00757 4.06e-116 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
NKIHKOBL_00758 1.83e-177 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NKIHKOBL_00759 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NKIHKOBL_00760 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NKIHKOBL_00761 1.37e-99 yhaI - - L - - - Membrane
NKIHKOBL_00762 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NKIHKOBL_00763 1.39e-33 - - - L ko:K07491 - ko00000 Transposase
NKIHKOBL_00764 5.58e-62 XK27_03610 - - K - - - Gnat family
NKIHKOBL_00765 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NKIHKOBL_00766 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
NKIHKOBL_00767 1.32e-143 ung2 - - L - - - Uracil-DNA glycosylase
NKIHKOBL_00770 7.14e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NKIHKOBL_00771 1.28e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NKIHKOBL_00772 1.19e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NKIHKOBL_00773 6.39e-151 clcA2 - - P - - - chloride
NKIHKOBL_00774 3.81e-13 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
NKIHKOBL_00775 4.28e-105 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
NKIHKOBL_00776 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
NKIHKOBL_00777 1.51e-314 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NKIHKOBL_00778 2.22e-173 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
NKIHKOBL_00779 2.31e-139 capA - - M - - - biosynthesis protein
NKIHKOBL_00780 1.23e-151 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
NKIHKOBL_00781 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NKIHKOBL_00782 6.25e-74 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
NKIHKOBL_00783 1.13e-100 lspL 5.1.3.6 - M ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 epimerase dehydratase
NKIHKOBL_00784 2.96e-45 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKIHKOBL_00785 9.79e-254 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NKIHKOBL_00786 3.64e-191 - - - M - - - Glycosyl transferases group 1
NKIHKOBL_00787 2.2e-47 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NKIHKOBL_00788 1.16e-38 - - - M - - - Psort location Cytoplasmic, score 8.87
NKIHKOBL_00789 1.12e-43 cps4F - - M - - - Glycosyl transferases group 1
NKIHKOBL_00790 9.97e-129 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NKIHKOBL_00791 4.44e-74 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NKIHKOBL_00792 1.58e-22 rfbF - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
NKIHKOBL_00793 3.19e-76 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
NKIHKOBL_00794 1.21e-25 - - - - - - - -
NKIHKOBL_00795 8.49e-29 - - - M - - - Glycosyltransferase WbsX
NKIHKOBL_00796 1.09e-101 - - - M - - - Glycosyl transferase, family 2
NKIHKOBL_00798 1.95e-44 - - - L - - - Transposase DDE domain
NKIHKOBL_00799 8.67e-202 - - - G - - - Phosphodiester glycosidase
NKIHKOBL_00800 1.19e-185 - - - K - - - Cell envelope-related transcriptional attenuator domain
NKIHKOBL_00801 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00802 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00804 1.63e-121 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
NKIHKOBL_00805 3.19e-285 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NKIHKOBL_00806 6.98e-139 yutD - - J - - - protein conserved in bacteria
NKIHKOBL_00807 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_00809 5.56e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NKIHKOBL_00810 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKIHKOBL_00811 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
NKIHKOBL_00812 2.25e-61 ftsL - - D - - - cell division protein FtsL
NKIHKOBL_00813 4.73e-244 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NKIHKOBL_00814 3.08e-118 - - - - - - - -
NKIHKOBL_00815 1.08e-54 - - - - - - - -
NKIHKOBL_00817 1.58e-42 - - - J - - - Protein of unknown function (DUF805)
NKIHKOBL_00818 1.79e-11 - - - D - - - nuclear chromosome segregation
NKIHKOBL_00819 1.22e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKIHKOBL_00820 4.99e-182 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKIHKOBL_00821 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NKIHKOBL_00822 3.02e-171 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00823 1.22e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NKIHKOBL_00824 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NKIHKOBL_00825 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NKIHKOBL_00826 2.47e-155 - - - S - - - membrane
NKIHKOBL_00827 1.31e-98 - - - K - - - LytTr DNA-binding domain
NKIHKOBL_00828 2.92e-81 - - - KT - - - response to antibiotic
NKIHKOBL_00829 2.76e-20 - - - KT - - - response to antibiotic
NKIHKOBL_00830 5.56e-93 yebC - - M - - - Membrane
NKIHKOBL_00831 1.77e-24 yebC - - M - - - Membrane
NKIHKOBL_00832 0.0 - - - S - - - hydrolases of the HAD superfamily
NKIHKOBL_00833 8.08e-223 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NKIHKOBL_00834 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKIHKOBL_00835 1.16e-244 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKIHKOBL_00836 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NKIHKOBL_00837 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKIHKOBL_00838 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKIHKOBL_00839 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NKIHKOBL_00841 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKIHKOBL_00842 2.37e-220 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
NKIHKOBL_00843 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_00844 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NKIHKOBL_00845 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NKIHKOBL_00846 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NKIHKOBL_00849 2.63e-240 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NKIHKOBL_00850 1.88e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NKIHKOBL_00851 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NKIHKOBL_00852 1.1e-147 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NKIHKOBL_00853 1.24e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKIHKOBL_00854 5.27e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKIHKOBL_00855 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
NKIHKOBL_00856 4.63e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NKIHKOBL_00857 2.07e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
NKIHKOBL_00858 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NKIHKOBL_00859 8.38e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NKIHKOBL_00860 1.99e-58 yktA - - S - - - Belongs to the UPF0223 family
NKIHKOBL_00861 7.52e-95 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NKIHKOBL_00862 1.28e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NKIHKOBL_00863 5.24e-195 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKIHKOBL_00864 5.47e-61 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
NKIHKOBL_00865 1.02e-124 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
NKIHKOBL_00866 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
NKIHKOBL_00867 1.48e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NKIHKOBL_00868 5.48e-79 - - - S - - - haloacid dehalogenase-like hydrolase
NKIHKOBL_00869 6.24e-78 - - - Q - - - phosphatase activity
NKIHKOBL_00870 2.95e-307 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
NKIHKOBL_00871 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NKIHKOBL_00872 7.07e-307 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
NKIHKOBL_00873 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKIHKOBL_00874 2.76e-45 - - - L ko:K07491 - ko00000 Transposase
NKIHKOBL_00875 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NKIHKOBL_00877 1.94e-32 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_00878 2.39e-50 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
NKIHKOBL_00879 1.24e-279 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKIHKOBL_00880 8.16e-111 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_00881 3.22e-156 - - - L - - - Transposase
NKIHKOBL_00882 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
NKIHKOBL_00884 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
NKIHKOBL_00885 1.83e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKIHKOBL_00886 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NKIHKOBL_00887 7.41e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
NKIHKOBL_00888 3.04e-200 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NKIHKOBL_00889 4.39e-42 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00890 4.24e-111 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00891 5.89e-70 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00892 7.09e-84 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00893 2.64e-159 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
NKIHKOBL_00894 2.13e-44 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
NKIHKOBL_00895 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
NKIHKOBL_00896 1.43e-97 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
NKIHKOBL_00897 1.17e-26 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
NKIHKOBL_00898 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NKIHKOBL_00900 1.82e-17 - - - - - - - -
NKIHKOBL_00901 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
NKIHKOBL_00902 2.15e-158 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NKIHKOBL_00903 2.87e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NKIHKOBL_00904 2.6e-174 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NKIHKOBL_00905 4.7e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NKIHKOBL_00906 1.25e-23 - - - D - - - nuclear chromosome segregation
NKIHKOBL_00907 1.88e-176 yejC - - S - - - cyclic nucleotide-binding protein
NKIHKOBL_00908 2.08e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NKIHKOBL_00909 3.04e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NKIHKOBL_00910 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NKIHKOBL_00911 2.45e-211 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NKIHKOBL_00912 2.63e-44 - - - K - - - Cold shock protein domain
NKIHKOBL_00913 8.77e-56 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
NKIHKOBL_00914 7.28e-268 - - - EGP - - - Transmembrane secretion effector
NKIHKOBL_00915 0.0 - - - F - - - NUDIX domain
NKIHKOBL_00916 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKIHKOBL_00917 4.48e-186 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
NKIHKOBL_00919 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00920 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_00921 4.12e-253 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKIHKOBL_00922 7.37e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NKIHKOBL_00923 3.52e-292 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
NKIHKOBL_00924 4.15e-170 rr02 - - KT - - - response regulator
NKIHKOBL_00925 6.56e-279 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKIHKOBL_00926 2.86e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NKIHKOBL_00927 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NKIHKOBL_00928 6.51e-249 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NKIHKOBL_00929 2.68e-39 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
NKIHKOBL_00931 2.6e-183 - - - F - - - Phosphorylase superfamily
NKIHKOBL_00932 4.5e-73 - - - S - - - VIT family
NKIHKOBL_00933 1.2e-55 - - - S - - - VIT family
NKIHKOBL_00934 3.68e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NKIHKOBL_00935 1.83e-280 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NKIHKOBL_00936 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
NKIHKOBL_00937 2.16e-57 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NKIHKOBL_00938 1.9e-316 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKIHKOBL_00939 3.96e-137 - - - J ko:K09962 - ko00000 protein conserved in bacteria
NKIHKOBL_00940 2.99e-191 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NKIHKOBL_00941 6.82e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NKIHKOBL_00942 1.5e-231 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
NKIHKOBL_00943 9.21e-244 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NKIHKOBL_00944 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKIHKOBL_00945 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
NKIHKOBL_00946 1.47e-41 - - - - - - - -
NKIHKOBL_00947 3.48e-150 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NKIHKOBL_00949 9.15e-10 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
NKIHKOBL_00950 4.12e-59 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
NKIHKOBL_00951 7.8e-06 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
NKIHKOBL_00952 2.09e-244 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NKIHKOBL_00953 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NKIHKOBL_00954 5.47e-29 - - - - - - - -
NKIHKOBL_00955 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKIHKOBL_00956 1.35e-60 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKIHKOBL_00957 6.04e-89 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKIHKOBL_00958 2.35e-211 - - - S - - - Protein of unknown function (DUF3114)
NKIHKOBL_00959 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
NKIHKOBL_00960 1.01e-151 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NKIHKOBL_00961 3.81e-35 - - - K - - - hmm pf08876
NKIHKOBL_00962 1.76e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NKIHKOBL_00963 3.65e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
NKIHKOBL_00964 5.15e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKIHKOBL_00965 7.02e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKIHKOBL_00966 2.97e-30 - - - - - - - -
NKIHKOBL_00967 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKIHKOBL_00968 1.93e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NKIHKOBL_00969 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NKIHKOBL_00970 8.67e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
NKIHKOBL_00971 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
NKIHKOBL_00972 1.1e-20 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
NKIHKOBL_00973 3.01e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NKIHKOBL_00974 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKIHKOBL_00975 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKIHKOBL_00976 4.29e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NKIHKOBL_00977 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
NKIHKOBL_00980 1.44e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
NKIHKOBL_00983 6.33e-132 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
NKIHKOBL_00984 2.5e-90 - - - M - - - Pfam SNARE associated Golgi protein
NKIHKOBL_00985 3.82e-295 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
NKIHKOBL_00986 1.83e-74 - - - S - - - oxidoreductase
NKIHKOBL_00987 2.73e-84 - - - S - - - oxidoreductase
NKIHKOBL_00988 1.29e-64 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NKIHKOBL_00989 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NKIHKOBL_00990 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NKIHKOBL_00991 1.06e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKIHKOBL_00992 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
NKIHKOBL_00993 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKIHKOBL_00994 4.45e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_00995 7.39e-103 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
NKIHKOBL_00996 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NKIHKOBL_00997 9.87e-12 - - - - - - - -
NKIHKOBL_00998 1.27e-135 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NKIHKOBL_00999 7.29e-61 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NKIHKOBL_01000 2.87e-47 yugF - - I - - - carboxylic ester hydrolase activity
NKIHKOBL_01001 5.04e-29 - - - I - - - Alpha/beta hydrolase family
NKIHKOBL_01002 8.45e-203 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKIHKOBL_01003 2.91e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NKIHKOBL_01004 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
NKIHKOBL_01005 7.55e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKIHKOBL_01006 3.61e-84 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NKIHKOBL_01007 1.21e-69 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NKIHKOBL_01008 2.18e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NKIHKOBL_01009 9.96e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NKIHKOBL_01010 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKIHKOBL_01011 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NKIHKOBL_01012 4.45e-136 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NKIHKOBL_01013 2.94e-281 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
NKIHKOBL_01014 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NKIHKOBL_01015 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NKIHKOBL_01016 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NKIHKOBL_01017 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKIHKOBL_01018 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
NKIHKOBL_01019 7e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
NKIHKOBL_01020 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
NKIHKOBL_01021 2.03e-35 XK27_07735 - - S - - - YjbR
NKIHKOBL_01022 6.38e-130 yyaQ - - V - - - Protein conserved in bacteria
NKIHKOBL_01023 6.29e-117 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NKIHKOBL_01024 4.6e-136 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NKIHKOBL_01025 1.03e-101 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NKIHKOBL_01026 1.75e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NKIHKOBL_01027 2.22e-34 WQ51_00785 - - - - - - -
NKIHKOBL_01028 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NKIHKOBL_01029 1.45e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NKIHKOBL_01030 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NKIHKOBL_01031 4.21e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKIHKOBL_01032 1.24e-258 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKIHKOBL_01033 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKIHKOBL_01034 1.92e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NKIHKOBL_01035 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
NKIHKOBL_01036 6.06e-223 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NKIHKOBL_01037 1.77e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NKIHKOBL_01038 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKIHKOBL_01039 3.43e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NKIHKOBL_01040 0.0 msrR - - K - - - Transcriptional regulator
NKIHKOBL_01041 7.66e-191 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
NKIHKOBL_01042 3.83e-257 - - - I - - - acyl-CoA dehydrogenase
NKIHKOBL_01043 5.21e-126 mip - - S - - - hydroperoxide reductase activity
NKIHKOBL_01044 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKIHKOBL_01045 9.57e-132 - - - - - - - -
NKIHKOBL_01046 2.13e-44 - - - K - - - Cro/C1-type HTH DNA-binding domain
NKIHKOBL_01047 4.96e-59 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
NKIHKOBL_01049 4.59e-124 - - - - - - - -
NKIHKOBL_01050 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NKIHKOBL_01051 1.61e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_01052 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_01053 6.13e-236 - - - S - - - CRISPR-associated protein Csn2 subfamily St
NKIHKOBL_01054 4.65e-189 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
NKIHKOBL_01055 4.63e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
NKIHKOBL_01057 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
NKIHKOBL_01058 1.45e-55 WQ51_05770 - - KT - - - PspC domain
NKIHKOBL_01059 2.36e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NKIHKOBL_01060 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKIHKOBL_01061 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKIHKOBL_01062 1.66e-91 ytxH - - S - - - General stress protein
NKIHKOBL_01064 1.23e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NKIHKOBL_01065 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NKIHKOBL_01066 3.62e-60 - - - S - - - CHY zinc finger
NKIHKOBL_01067 2.67e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
NKIHKOBL_01069 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
NKIHKOBL_01070 3.16e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NKIHKOBL_01071 2.07e-18 - - - - - - - -
NKIHKOBL_01072 1.97e-264 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NKIHKOBL_01073 8.02e-285 - - - L - - - DNA mismatch repair enzyme MutH
NKIHKOBL_01074 7.82e-40 - - - S - - - SIR2-like domain
NKIHKOBL_01075 1.34e-39 - - - S - - - SIR2-like domain
NKIHKOBL_01076 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NKIHKOBL_01077 2.07e-211 - - - M - - - LysM domain
NKIHKOBL_01078 2.16e-29 - - - - - - - -
NKIHKOBL_01079 3.26e-224 - - - S ko:K07025 - ko00000 hydrolase
NKIHKOBL_01080 1.02e-149 pgm - - G - - - Phosphoglycerate mutase
NKIHKOBL_01081 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NKIHKOBL_01082 9.89e-197 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
NKIHKOBL_01083 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
NKIHKOBL_01084 2.83e-145 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKIHKOBL_01085 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
NKIHKOBL_01086 1.03e-27 - - - S - - - Protein of unknown function (DUF2974)
NKIHKOBL_01087 3.06e-21 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NKIHKOBL_01088 3.33e-121 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NKIHKOBL_01089 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NKIHKOBL_01090 1.79e-199 - - - S - - - Bacteriophage abortive infection AbiH
NKIHKOBL_01092 4.02e-164 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NKIHKOBL_01093 8.71e-75 - - - S - - - Phage derived protein Gp49-like (DUF891)
NKIHKOBL_01094 1.8e-56 - - - K - - - Helix-turn-helix domain
NKIHKOBL_01095 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NKIHKOBL_01096 7.65e-61 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
NKIHKOBL_01097 1.77e-26 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NKIHKOBL_01098 3.34e-175 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NKIHKOBL_01099 1.04e-118 lemA - - S ko:K03744 - ko00000 LemA family
NKIHKOBL_01100 3.15e-185 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NKIHKOBL_01101 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NKIHKOBL_01102 2.18e-73 - - - S - - - Domain of unknown function (DUF4430)
NKIHKOBL_01103 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NKIHKOBL_01104 2.71e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NKIHKOBL_01105 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NKIHKOBL_01107 6.67e-123 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NKIHKOBL_01108 8.39e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NKIHKOBL_01109 1.8e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NKIHKOBL_01110 2.37e-249 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NKIHKOBL_01111 5.03e-17 - - - L ko:K07497 - ko00000 transposition
NKIHKOBL_01112 1.52e-52 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_01113 7.37e-60 - - - L ko:K07483 - ko00000 Transposase
NKIHKOBL_01114 2.84e-203 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
NKIHKOBL_01115 2.46e-24 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_01116 8.12e-24 - - - L ko:K07483 - ko00000 Transposase
NKIHKOBL_01117 3.19e-25 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_01118 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
NKIHKOBL_01119 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
NKIHKOBL_01123 1.88e-69 - - - S - - - Virulence-associated protein E
NKIHKOBL_01124 1.18e-164 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
NKIHKOBL_01125 1.9e-30 - - - - - - - -
NKIHKOBL_01130 1.52e-27 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NKIHKOBL_01131 1.55e-24 - - - K - - - transcriptional
NKIHKOBL_01132 1.57e-280 - - - L - - - Belongs to the 'phage' integrase family
NKIHKOBL_01134 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKIHKOBL_01135 2.2e-212 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
NKIHKOBL_01136 2.56e-166 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
NKIHKOBL_01137 2.67e-184 - - - - - - - -
NKIHKOBL_01138 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
NKIHKOBL_01139 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
NKIHKOBL_01140 1.15e-244 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
NKIHKOBL_01141 6.04e-272 - - - M ko:K06330 - ko00000 CotH kinase protein
NKIHKOBL_01142 2.46e-68 - - - G - - - Domain of unknown function (DUF4832)
NKIHKOBL_01143 3.55e-12 - - - G - - - Domain of unknown function (DUF4832)
NKIHKOBL_01144 6.05e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NKIHKOBL_01146 3.41e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKIHKOBL_01147 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
NKIHKOBL_01148 6.78e-177 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NKIHKOBL_01149 4.11e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NKIHKOBL_01150 7.97e-157 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01151 2.31e-192 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NKIHKOBL_01152 5.43e-180 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_01153 2.49e-166 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKIHKOBL_01154 9.32e-316 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKIHKOBL_01155 1.77e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
NKIHKOBL_01156 2.58e-294 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
NKIHKOBL_01157 5.66e-189 XK27_00835 - - S - - - hydrolases of the HAD superfamily
NKIHKOBL_01158 9.96e-69 XK27_00115 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
NKIHKOBL_01159 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
NKIHKOBL_01160 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
NKIHKOBL_01161 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NKIHKOBL_01162 2.04e-229 - - - S - - - Calcineurin-like phosphoesterase
NKIHKOBL_01163 2.13e-263 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NKIHKOBL_01164 6.25e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NKIHKOBL_01165 7.31e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NKIHKOBL_01166 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NKIHKOBL_01167 3.52e-120 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NKIHKOBL_01168 4.97e-231 XK27_05220 - - S - - - permease
NKIHKOBL_01169 1.34e-285 XK27_05225 - - G - - - COG0457 FOG TPR repeat
NKIHKOBL_01170 1.95e-127 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NKIHKOBL_01171 5.04e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NKIHKOBL_01172 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
NKIHKOBL_01173 6.79e-48 XK27_09115 - - M - - - LysM domain
NKIHKOBL_01174 8.33e-156 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NKIHKOBL_01175 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NKIHKOBL_01176 5.79e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NKIHKOBL_01177 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NKIHKOBL_01178 1.02e-43 - - - S - - - Glycosyltransferase like family 2
NKIHKOBL_01179 9.51e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NKIHKOBL_01180 1.29e-54 - - - L ko:K07497 - ko00000 transposition
NKIHKOBL_01181 6.81e-238 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKIHKOBL_01194 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKIHKOBL_01195 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKIHKOBL_01196 8.82e-124 ypsA - - S - - - Belongs to the UPF0398 family
NKIHKOBL_01197 3.39e-67 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NKIHKOBL_01198 6.16e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NKIHKOBL_01199 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NKIHKOBL_01200 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
NKIHKOBL_01201 3.69e-27 XK27_11680 - - - - - - -
NKIHKOBL_01202 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NKIHKOBL_01203 1.24e-104 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
NKIHKOBL_01204 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKIHKOBL_01205 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NKIHKOBL_01206 2.91e-79 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_01207 1.52e-211 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKIHKOBL_01208 3.32e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NKIHKOBL_01209 6.83e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKIHKOBL_01210 8.25e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
NKIHKOBL_01211 2.43e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NKIHKOBL_01214 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NKIHKOBL_01215 2.12e-119 - - - K - - - transcriptional regulator
NKIHKOBL_01216 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
NKIHKOBL_01217 1.89e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NKIHKOBL_01218 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NKIHKOBL_01219 7.82e-128 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NKIHKOBL_01220 1.74e-111 ykuL - - S - - - CBS domain
NKIHKOBL_01221 3.26e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NKIHKOBL_01222 5.32e-153 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKIHKOBL_01223 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKIHKOBL_01224 1.82e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NKIHKOBL_01225 1.23e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NKIHKOBL_01226 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
NKIHKOBL_01227 1.15e-313 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
NKIHKOBL_01228 2.22e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NKIHKOBL_01229 4.83e-118 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NKIHKOBL_01230 6.62e-148 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
NKIHKOBL_01231 1.03e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NKIHKOBL_01232 5.6e-45 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
NKIHKOBL_01233 1.05e-45 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NKIHKOBL_01234 3.47e-78 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NKIHKOBL_01235 5.3e-35 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
NKIHKOBL_01236 2.72e-36 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
NKIHKOBL_01237 1.34e-89 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NKIHKOBL_01238 5.77e-68 yhaI - - L - - - Membrane
NKIHKOBL_01239 1.76e-43 - - - S - - - Domain of unknown function (DUF4173)
NKIHKOBL_01240 8.35e-163 - - - S - - - Domain of unknown function (DUF4173)
NKIHKOBL_01241 2.16e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
NKIHKOBL_01242 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NKIHKOBL_01243 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NKIHKOBL_01244 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NKIHKOBL_01245 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
NKIHKOBL_01246 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NKIHKOBL_01247 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NKIHKOBL_01248 9.91e-204 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NKIHKOBL_01249 5.71e-21 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NKIHKOBL_01250 2e-192 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NKIHKOBL_01251 6.8e-176 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
NKIHKOBL_01252 4.48e-170 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NKIHKOBL_01254 4.5e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NKIHKOBL_01255 7.2e-27 - - - V - - - D-alanyl-D-alanine carboxypeptidase
NKIHKOBL_01256 4.19e-101 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NKIHKOBL_01257 1.5e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKIHKOBL_01258 7.69e-103 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01259 6.06e-99 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01260 3.5e-92 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01262 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
NKIHKOBL_01263 4.07e-52 ynzC - - S - - - UPF0291 protein
NKIHKOBL_01264 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NKIHKOBL_01265 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NKIHKOBL_01266 2.41e-79 - - - S - - - membrane
NKIHKOBL_01267 8.89e-80 - - - - - - - -
NKIHKOBL_01268 2.36e-35 - - - - - - - -
NKIHKOBL_01269 2.07e-71 - - - - - - - -
NKIHKOBL_01270 8.41e-282 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NKIHKOBL_01271 3.54e-88 phoU_1 - - P ko:K03324 - ko00000,ko02000 sodium-dependent phosphate transmembrane transporter activity
NKIHKOBL_01272 3.41e-192 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
NKIHKOBL_01273 7.94e-141 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
NKIHKOBL_01274 3.22e-71 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NKIHKOBL_01275 1.39e-297 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
NKIHKOBL_01276 2.42e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NKIHKOBL_01277 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
NKIHKOBL_01278 3.89e-175 yaaT - - S - - - stage 0 sporulation protein
NKIHKOBL_01279 7.84e-207 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
NKIHKOBL_01280 1.19e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKIHKOBL_01281 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NKIHKOBL_01282 7.86e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKIHKOBL_01283 3.51e-293 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NKIHKOBL_01284 6.23e-97 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NKIHKOBL_01285 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKIHKOBL_01286 9.48e-204 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKIHKOBL_01287 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKIHKOBL_01288 3.66e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKIHKOBL_01289 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
NKIHKOBL_01290 4.44e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NKIHKOBL_01291 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKIHKOBL_01292 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NKIHKOBL_01293 7.34e-63 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NKIHKOBL_01294 4.13e-143 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NKIHKOBL_01295 2.62e-17 coiA - - S ko:K06198 - ko00000 Competence protein
NKIHKOBL_01297 1.32e-195 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
NKIHKOBL_01298 3.69e-198 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NKIHKOBL_01299 7.29e-304 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NKIHKOBL_01300 6.7e-189 icaB - - G - - - deacetylase
NKIHKOBL_01301 9.21e-267 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NKIHKOBL_01302 2.56e-164 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NKIHKOBL_01303 4.21e-285 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NKIHKOBL_01304 1.12e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NKIHKOBL_01305 1.17e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
NKIHKOBL_01306 1.29e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKIHKOBL_01307 2.79e-158 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
NKIHKOBL_01308 1.94e-186 - - - M - - - GBS Bsp-like repeat
NKIHKOBL_01309 1.67e-29 - - - M - - - GBS Bsp-like repeat
NKIHKOBL_01310 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKIHKOBL_01311 6.55e-237 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
NKIHKOBL_01312 2.39e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
NKIHKOBL_01313 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NKIHKOBL_01314 3.31e-238 coiA - - S ko:K06198 - ko00000 Competence protein
NKIHKOBL_01315 2.54e-211 - - - K - - - transcriptional regulator (lysR family)
NKIHKOBL_01316 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKIHKOBL_01320 6.47e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NKIHKOBL_01321 3.19e-90 sip - - M - - - LysM domain protein
NKIHKOBL_01322 1.92e-38 - - - L ko:K07483 - ko00000 transposase activity
NKIHKOBL_01323 4.64e-135 yfiF3 - - K - - - sequence-specific DNA binding
NKIHKOBL_01324 1.56e-45 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
NKIHKOBL_01325 4.78e-142 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_01326 1.07e-09 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_01327 2.39e-86 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01328 1.06e-170 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NKIHKOBL_01329 3.65e-134 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NKIHKOBL_01330 0.0 dtpT - - E ko:K03305 - ko00000 transporter
NKIHKOBL_01332 2.1e-78 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
NKIHKOBL_01333 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NKIHKOBL_01334 5.04e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NKIHKOBL_01335 4.55e-95 - - - S - - - Psort location Cytoplasmic, score
NKIHKOBL_01336 7.98e-18 - - - S - - - Psort location Cytoplasmic, score
NKIHKOBL_01337 6.42e-262 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
NKIHKOBL_01338 2.45e-214 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
NKIHKOBL_01339 1.62e-150 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
NKIHKOBL_01340 7.5e-83 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
NKIHKOBL_01341 0.0 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
NKIHKOBL_01342 7.74e-174 - - - S - - - Pfam:DUF2276
NKIHKOBL_01343 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_01344 1.56e-230 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NKIHKOBL_01345 1.17e-223 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NKIHKOBL_01346 8.38e-190 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NKIHKOBL_01347 4.28e-125 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
NKIHKOBL_01348 9.76e-153 - - - S - - - TraX protein
NKIHKOBL_01350 5.51e-38 - 3.4.13.21 - I ko:K05995,ko:K06888 - ko00000,ko01000,ko01002 Protein conserved in bacteria
NKIHKOBL_01351 1.01e-115 - - - F - - - Belongs to the Nudix hydrolase family
NKIHKOBL_01352 1.86e-243 - - - - - - - -
NKIHKOBL_01353 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NKIHKOBL_01355 2.17e-51 dinF - - V - - - Mate efflux family protein
NKIHKOBL_01356 1.34e-92 dinF - - V - - - Mate efflux family protein
NKIHKOBL_01357 9.2e-25 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
NKIHKOBL_01358 6.66e-19 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
NKIHKOBL_01359 6.95e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
NKIHKOBL_01360 9.83e-187 - - - F - - - Phosphorylase superfamily
NKIHKOBL_01363 2.84e-102 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NKIHKOBL_01364 3.95e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NKIHKOBL_01365 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
NKIHKOBL_01366 2.78e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
NKIHKOBL_01367 2.72e-184 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NKIHKOBL_01368 2.11e-69 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NKIHKOBL_01369 3.17e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NKIHKOBL_01370 1.09e-126 - - - K - - - Transcriptional regulator, TetR family
NKIHKOBL_01371 9.28e-15 - - - - - - - -
NKIHKOBL_01372 3.51e-146 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NKIHKOBL_01373 4e-141 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01374 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NKIHKOBL_01375 2.02e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
NKIHKOBL_01376 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NKIHKOBL_01377 9.61e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
NKIHKOBL_01378 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
NKIHKOBL_01379 4.44e-173 - - - S - - - Putative SAM-dependent methyltransferase
NKIHKOBL_01380 1.04e-46 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKIHKOBL_01381 1.1e-46 - - - V - - - efflux transmembrane transporter activity
NKIHKOBL_01382 3.93e-47 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
NKIHKOBL_01383 3.74e-34 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
NKIHKOBL_01384 3.14e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKIHKOBL_01385 2.46e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NKIHKOBL_01386 2.31e-306 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NKIHKOBL_01387 1.52e-81 manO - - S - - - protein conserved in bacteria
NKIHKOBL_01388 8.21e-215 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NKIHKOBL_01389 4.19e-162 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
NKIHKOBL_01390 6.6e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01391 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
NKIHKOBL_01392 1.46e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NKIHKOBL_01393 4.39e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
NKIHKOBL_01394 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
NKIHKOBL_01395 6.67e-120 - - - M - - - Acetyltransferase GNAT Family
NKIHKOBL_01396 1.29e-280 brpA - - K - - - Transcriptional
NKIHKOBL_01397 3.06e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NKIHKOBL_01398 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NKIHKOBL_01399 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
NKIHKOBL_01400 2.19e-56 ylxQ - - J - - - ribosomal protein
NKIHKOBL_01401 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKIHKOBL_01402 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKIHKOBL_01403 1.44e-29 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NKIHKOBL_01404 2.68e-49 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NKIHKOBL_01405 5.54e-273 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
NKIHKOBL_01406 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKIHKOBL_01407 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NKIHKOBL_01408 4.89e-115 pacL - - P - - - cation transport ATPase
NKIHKOBL_01409 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NKIHKOBL_01410 5.65e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NKIHKOBL_01412 3.28e-06 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
NKIHKOBL_01413 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKIHKOBL_01414 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NKIHKOBL_01415 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
NKIHKOBL_01416 4.33e-62 ylbG - - S - - - UPF0298 protein
NKIHKOBL_01417 3.09e-268 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NKIHKOBL_01418 8.19e-190 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKIHKOBL_01419 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKIHKOBL_01420 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NKIHKOBL_01421 5.36e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NKIHKOBL_01422 6.64e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
NKIHKOBL_01423 2.44e-54 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
NKIHKOBL_01424 1.85e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NKIHKOBL_01425 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NKIHKOBL_01426 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NKIHKOBL_01427 1.19e-157 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NKIHKOBL_01428 1.18e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NKIHKOBL_01429 2.3e-15 - - - H - - - gamma-glutamylcysteine synthetase
NKIHKOBL_01430 8e-24 - - - H - - - gamma-glutamylcysteine synthetase
NKIHKOBL_01431 7.55e-142 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
NKIHKOBL_01433 2.85e-210 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
NKIHKOBL_01434 0.0 - - - H - - - C-5 cytosine-specific DNA methylase
NKIHKOBL_01435 5.73e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
NKIHKOBL_01436 1.14e-277 - - - S - - - MvaI/BcnI restriction endonuclease family
NKIHKOBL_01438 0.000346 - - - - - - - -
NKIHKOBL_01439 4.65e-42 - - - S - - - Hypothetical protein (DUF2513)
NKIHKOBL_01440 4.01e-41 - - - - - - - -
NKIHKOBL_01441 2.03e-53 - - - - - - - -
NKIHKOBL_01446 5.34e-176 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01447 5.45e-159 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKIHKOBL_01448 3.75e-18 - - - M - - - Acetyltransferase GNAT Family
NKIHKOBL_01449 2.79e-55 - - - K - - - Putative DNA-binding domain
NKIHKOBL_01452 2.35e-180 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NKIHKOBL_01453 4.35e-116 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NKIHKOBL_01454 2.35e-185 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
NKIHKOBL_01455 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NKIHKOBL_01456 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NKIHKOBL_01457 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKIHKOBL_01458 3.89e-241 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKIHKOBL_01459 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
NKIHKOBL_01460 5.37e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKIHKOBL_01461 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NKIHKOBL_01462 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKIHKOBL_01463 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NKIHKOBL_01464 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKIHKOBL_01465 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NKIHKOBL_01466 2.12e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NKIHKOBL_01467 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NKIHKOBL_01468 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
NKIHKOBL_01469 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKIHKOBL_01470 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKIHKOBL_01471 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKIHKOBL_01472 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKIHKOBL_01473 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKIHKOBL_01474 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKIHKOBL_01475 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKIHKOBL_01476 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKIHKOBL_01477 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKIHKOBL_01478 4.36e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NKIHKOBL_01479 3.58e-93 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKIHKOBL_01480 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKIHKOBL_01481 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKIHKOBL_01482 1.99e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKIHKOBL_01483 7.19e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKIHKOBL_01484 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NKIHKOBL_01485 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NKIHKOBL_01486 7.78e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKIHKOBL_01487 7.41e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NKIHKOBL_01488 1.78e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NKIHKOBL_01489 0.0 XK27_09800 - - I - - - Acyltransferase
NKIHKOBL_01490 2.43e-47 - - - S - - - MORN repeat protein
NKIHKOBL_01491 2.29e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKIHKOBL_01492 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NKIHKOBL_01493 3.91e-109 flaR - - F - - - topology modulation protein
NKIHKOBL_01494 3.14e-244 - - - EGP - - - Major Facilitator Superfamily
NKIHKOBL_01495 3.96e-253 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
NKIHKOBL_01496 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
NKIHKOBL_01497 1.44e-192 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NKIHKOBL_01498 6.47e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NKIHKOBL_01499 3.71e-119 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NKIHKOBL_01500 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NKIHKOBL_01501 3.04e-110 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NKIHKOBL_01502 1.08e-106 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NKIHKOBL_01503 4.45e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NKIHKOBL_01504 7.42e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NKIHKOBL_01505 9.67e-76 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
NKIHKOBL_01506 1.47e-178 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_01507 2.06e-181 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_01508 1.5e-61 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKIHKOBL_01509 8.28e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NKIHKOBL_01510 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKIHKOBL_01511 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NKIHKOBL_01512 3.09e-13 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NKIHKOBL_01513 1.69e-32 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NKIHKOBL_01514 2.5e-68 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NKIHKOBL_01515 3.02e-65 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NKIHKOBL_01516 9.52e-303 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKIHKOBL_01517 2.96e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKIHKOBL_01518 1.63e-146 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NKIHKOBL_01519 2.59e-258 XK27_00055 - - P - - - Major Facilitator
NKIHKOBL_01520 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKIHKOBL_01521 8.47e-126 - - - V - - - VanZ like family
NKIHKOBL_01523 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_01524 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NKIHKOBL_01525 5.83e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NKIHKOBL_01526 8.3e-172 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NKIHKOBL_01527 7.24e-248 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NKIHKOBL_01528 1.82e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NKIHKOBL_01529 5.93e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NKIHKOBL_01530 2.82e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKIHKOBL_01531 4.61e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NKIHKOBL_01532 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NKIHKOBL_01533 5.77e-13 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NKIHKOBL_01534 1.34e-178 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NKIHKOBL_01535 9e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKIHKOBL_01536 4.03e-14 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKIHKOBL_01537 4.52e-54 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKIHKOBL_01538 3.42e-50 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKIHKOBL_01539 9.63e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01540 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01541 1.53e-82 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01542 3.49e-54 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01543 4.99e-78 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01544 2.62e-85 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01545 1.87e-29 - - - - - - - -
NKIHKOBL_01546 2.23e-200 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NKIHKOBL_01547 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKIHKOBL_01548 1.03e-284 - - - EGP - - - Major facilitator Superfamily
NKIHKOBL_01549 7.43e-94 adcR - - K - - - transcriptional
NKIHKOBL_01550 1.02e-174 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKIHKOBL_01551 1.09e-166 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01552 9.78e-207 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NKIHKOBL_01553 3.56e-86 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01554 1.42e-197 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
NKIHKOBL_01555 1.13e-136 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NKIHKOBL_01556 2e-201 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
NKIHKOBL_01557 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NKIHKOBL_01558 3.92e-163 yeeN - - K - - - transcriptional regulatory protein
NKIHKOBL_01559 9.27e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
NKIHKOBL_01560 1.76e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKIHKOBL_01561 1.83e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NKIHKOBL_01562 7.72e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NKIHKOBL_01563 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NKIHKOBL_01564 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
NKIHKOBL_01565 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_01566 6.35e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NKIHKOBL_01567 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NKIHKOBL_01568 1.08e-113 - - - S - - - Fusaric acid resistance protein-like
NKIHKOBL_01569 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NKIHKOBL_01570 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NKIHKOBL_01571 4.75e-53 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
NKIHKOBL_01572 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKIHKOBL_01573 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
NKIHKOBL_01574 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
NKIHKOBL_01575 4.41e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NKIHKOBL_01576 1.64e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKIHKOBL_01577 7.27e-148 XK27_12120 - - E - - - AzlC protein
NKIHKOBL_01578 3.85e-63 azlD - - E - - - branched-chain amino acid
NKIHKOBL_01579 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NKIHKOBL_01580 3.19e-146 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NKIHKOBL_01581 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKIHKOBL_01582 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NKIHKOBL_01583 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
NKIHKOBL_01584 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NKIHKOBL_01585 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKIHKOBL_01589 5.55e-292 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NKIHKOBL_01590 1.39e-50 XK27_05745 - - - - - - -
NKIHKOBL_01591 3.11e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NKIHKOBL_01592 1.2e-117 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKIHKOBL_01593 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKIHKOBL_01595 5.91e-159 - - - S - - - Pfam PF06570
NKIHKOBL_01596 8.18e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
NKIHKOBL_01597 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NKIHKOBL_01600 3.94e-75 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
NKIHKOBL_01601 6.03e-55 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
NKIHKOBL_01603 2.5e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
NKIHKOBL_01604 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NKIHKOBL_01605 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKIHKOBL_01606 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
NKIHKOBL_01607 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKIHKOBL_01608 3.28e-199 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
NKIHKOBL_01609 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
NKIHKOBL_01610 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NKIHKOBL_01611 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NKIHKOBL_01612 3.15e-175 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NKIHKOBL_01613 3.68e-271 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
NKIHKOBL_01616 5.91e-199 - - - K - - - Transcriptional activator, Rgg GadR MutR family
NKIHKOBL_01617 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NKIHKOBL_01618 1.01e-24 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
NKIHKOBL_01619 8.3e-67 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
NKIHKOBL_01620 4.95e-63 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKIHKOBL_01621 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NKIHKOBL_01622 3.66e-28 XK27_05470 - - E - - - Methionine synthase
NKIHKOBL_01623 6.2e-195 XK27_05470 - - E - - - Methionine synthase
NKIHKOBL_01624 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NKIHKOBL_01625 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NKIHKOBL_01626 2.93e-157 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKIHKOBL_01627 7.22e-199 - - - S - - - TraX protein
NKIHKOBL_01628 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKIHKOBL_01629 9.91e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NKIHKOBL_01630 1.79e-215 - - - GK - - - ROK family
NKIHKOBL_01631 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKIHKOBL_01632 1.46e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKIHKOBL_01633 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
NKIHKOBL_01634 1.3e-116 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NKIHKOBL_01635 8e-113 niaX - - - ko:K16788 - ko00000,ko02000 -
NKIHKOBL_01636 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKIHKOBL_01637 9e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NKIHKOBL_01638 3.67e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
NKIHKOBL_01639 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NKIHKOBL_01640 9.23e-59 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
NKIHKOBL_01641 1.07e-133 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NKIHKOBL_01642 7.7e-42 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NKIHKOBL_01643 1.53e-179 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKIHKOBL_01644 1.04e-48 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKIHKOBL_01645 1.35e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NKIHKOBL_01646 5.28e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
NKIHKOBL_01647 3.92e-134 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01648 4.47e-76 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
NKIHKOBL_01649 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NKIHKOBL_01650 2.18e-214 cpsY - - K - - - Transcriptional regulator
NKIHKOBL_01651 4.7e-107 - - - L ko:K07497 - ko00000 transposition
NKIHKOBL_01652 1.86e-153 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
NKIHKOBL_01653 4.73e-221 yeiH - - S - - - Membrane
NKIHKOBL_01655 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NKIHKOBL_01656 1.69e-128 XK27_10720 - - D - - - peptidase activity
NKIHKOBL_01657 8.54e-98 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
NKIHKOBL_01658 1.33e-07 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
NKIHKOBL_01659 9.82e-203 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NKIHKOBL_01660 1.1e-143 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NKIHKOBL_01661 3.85e-72 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NKIHKOBL_01662 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NKIHKOBL_01663 5.03e-311 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NKIHKOBL_01665 2.23e-298 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
NKIHKOBL_01666 1.56e-174 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
NKIHKOBL_01669 2.55e-33 - - - S - - - Bacteriocin class II with double-glycine leader peptide
NKIHKOBL_01670 0.000703 - - - - - - - -
NKIHKOBL_01674 5.99e-50 - - - L ko:K07483 - ko00000 transposase helper protein for IS981
NKIHKOBL_01675 1e-40 - - - M - - - transferase activity, transferring glycosyl groups
NKIHKOBL_01676 3.03e-09 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NKIHKOBL_01677 3.49e-149 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NKIHKOBL_01678 1.95e-48 - - - G - - - alpha-ribazole phosphatase activity
NKIHKOBL_01679 5.13e-39 - - - G - - - Belongs to the phosphoglycerate mutase family
NKIHKOBL_01680 1.68e-254 XK27_12525 - - S - - - hmm pf01594
NKIHKOBL_01681 2.27e-37 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
NKIHKOBL_01682 2.14e-123 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKIHKOBL_01683 1.15e-56 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
NKIHKOBL_01684 3.34e-52 - - - S - - - granule-associated protein
NKIHKOBL_01685 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
NKIHKOBL_01686 2.96e-20 - - - E - - - Lysophospholipase L1 and related esterases
NKIHKOBL_01687 1.35e-102 - - - E - - - GDSL-like protein
NKIHKOBL_01688 1.3e-201 - - - S - - - Phospholipase, patatin family
NKIHKOBL_01689 3.83e-277 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKIHKOBL_01690 6.69e-162 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NKIHKOBL_01691 2.94e-300 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NKIHKOBL_01692 1.27e-77 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01693 4.19e-53 - - - P - - - membrane protein (DUF2207)
NKIHKOBL_01694 1.07e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NKIHKOBL_01695 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKIHKOBL_01696 1.5e-30 XK27_08085 - - - - - - -
NKIHKOBL_01697 1.5e-119 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
NKIHKOBL_01698 2.04e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
NKIHKOBL_01699 2.41e-181 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
NKIHKOBL_01700 1.2e-158 - - - S - - - tigr01906
NKIHKOBL_01701 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NKIHKOBL_01702 5.49e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NKIHKOBL_01703 3.27e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NKIHKOBL_01705 6.86e-11 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01707 5.28e-34 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01708 1.43e-35 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01710 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
NKIHKOBL_01711 1.68e-229 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
NKIHKOBL_01712 3.93e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKIHKOBL_01713 5.4e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
NKIHKOBL_01714 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKIHKOBL_01715 3.72e-194 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
NKIHKOBL_01716 2.2e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
NKIHKOBL_01718 1.42e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NKIHKOBL_01719 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
NKIHKOBL_01720 1.27e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
NKIHKOBL_01721 2.5e-278 - - - P - - - chloride
NKIHKOBL_01722 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NKIHKOBL_01724 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NKIHKOBL_01725 1.75e-208 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKIHKOBL_01726 1.12e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NKIHKOBL_01727 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKIHKOBL_01728 2.38e-223 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NKIHKOBL_01729 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKIHKOBL_01730 2.75e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKIHKOBL_01731 1.06e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NKIHKOBL_01732 5.05e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NKIHKOBL_01733 2.58e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NKIHKOBL_01734 3.89e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKIHKOBL_01735 1.75e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NKIHKOBL_01736 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKIHKOBL_01737 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NKIHKOBL_01738 4.91e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NKIHKOBL_01739 6.85e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKIHKOBL_01740 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NKIHKOBL_01741 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01742 2.01e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
NKIHKOBL_01743 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKIHKOBL_01744 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NKIHKOBL_01746 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NKIHKOBL_01747 1.83e-277 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NKIHKOBL_01748 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
NKIHKOBL_01749 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NKIHKOBL_01750 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NKIHKOBL_01751 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKIHKOBL_01752 9.61e-247 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKIHKOBL_01753 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKIHKOBL_01754 6.01e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NKIHKOBL_01755 6.79e-91 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NKIHKOBL_01756 4.43e-82 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NKIHKOBL_01757 7.07e-40 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NKIHKOBL_01758 1.69e-117 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NKIHKOBL_01759 2.16e-32 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
NKIHKOBL_01760 2.18e-32 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NKIHKOBL_01761 1.86e-135 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
NKIHKOBL_01762 7.99e-283 - - - L ko:K07485 - ko00000 Transposase
NKIHKOBL_01763 1.92e-36 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKIHKOBL_01764 1.37e-49 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
NKIHKOBL_01765 2.99e-185 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
NKIHKOBL_01766 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
NKIHKOBL_01767 0.0 vpr 3.4.21.96 - O ko:K01361,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKIHKOBL_01768 1.5e-28 - - - L - - - Helix-turn-helix domain
NKIHKOBL_01769 1.68e-106 - - - L - - - Helix-turn-helix domain
NKIHKOBL_01770 1.21e-209 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_01771 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
NKIHKOBL_01772 1.01e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NKIHKOBL_01773 3.67e-215 - - - L ko:K07481 - ko00000 transposase, IS4 family
NKIHKOBL_01774 3.42e-119 - - - V - - - VanZ like family
NKIHKOBL_01775 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NKIHKOBL_01776 4.07e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NKIHKOBL_01777 1.92e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKIHKOBL_01778 5.91e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
NKIHKOBL_01779 1.28e-131 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
NKIHKOBL_01780 1.15e-189 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NKIHKOBL_01781 9.04e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NKIHKOBL_01782 2.86e-92 mesH - - S - - - GtrA-like protein
NKIHKOBL_01783 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKIHKOBL_01784 1.47e-217 ybbR - - S - - - Protein conserved in bacteria
NKIHKOBL_01785 1.15e-160 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKIHKOBL_01786 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
NKIHKOBL_01787 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NKIHKOBL_01788 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NKIHKOBL_01789 4.3e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
NKIHKOBL_01790 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
NKIHKOBL_01791 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NKIHKOBL_01792 6.73e-245 yfmL - - L - - - DEAD DEAH box helicase
NKIHKOBL_01793 5.79e-39 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NKIHKOBL_01794 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NKIHKOBL_01795 1.71e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NKIHKOBL_01796 1.4e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NKIHKOBL_01797 1.36e-215 lysR - - K - - - transcriptional regulator (lysR family)
NKIHKOBL_01808 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKIHKOBL_01809 4.87e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NKIHKOBL_01810 1.99e-48 XK27_02060 - - S - - - Transglycosylase associated protein
NKIHKOBL_01811 1.44e-72 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NKIHKOBL_01812 1.13e-125 XK27_03570 - - S ko:K19784 - ko00000 reductase
NKIHKOBL_01813 5.74e-41 - - - L ko:K07497 - ko00000 Integrase core domain protein
NKIHKOBL_01814 6.5e-306 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NKIHKOBL_01815 0.0 copB 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NKIHKOBL_01816 1e-74 amd - - E - - - COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NKIHKOBL_01817 1.5e-298 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NKIHKOBL_01818 5.43e-45 - - - - - - - -
NKIHKOBL_01819 6.44e-65 - - - L - - - Transposase
NKIHKOBL_01820 3.61e-132 - - - L ko:K07485 - ko00000 Transposase
NKIHKOBL_01821 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKIHKOBL_01822 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NKIHKOBL_01823 3.77e-307 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NKIHKOBL_01824 2.66e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
NKIHKOBL_01825 1.94e-05 - - - - - - - -
NKIHKOBL_01826 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NKIHKOBL_01827 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NKIHKOBL_01828 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKIHKOBL_01829 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NKIHKOBL_01830 3.04e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NKIHKOBL_01831 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
NKIHKOBL_01832 1.1e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NKIHKOBL_01833 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKIHKOBL_01834 9.27e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NKIHKOBL_01835 2.58e-261 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NKIHKOBL_01836 1.79e-111 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKIHKOBL_01837 3.66e-155 yveI - - S - - - Psort location CytoplasmicMembrane, score
NKIHKOBL_01841 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
NKIHKOBL_01842 0.0 ykpA - - S - - - abc transporter atp-binding protein
NKIHKOBL_01843 3.96e-195 XK27_10395 - - S - - - membrane
NKIHKOBL_01844 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NKIHKOBL_01845 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NKIHKOBL_01846 2.24e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NKIHKOBL_01847 3.7e-69 yaaA - - S - - - S4 domain protein YaaA
NKIHKOBL_01848 9.12e-301 albE - - S - - - Peptidase M16
NKIHKOBL_01849 7.64e-309 ymfH - - S - - - Peptidase M16
NKIHKOBL_01850 8.84e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
NKIHKOBL_01851 5.4e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKIHKOBL_01852 4.68e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKIHKOBL_01853 2.6e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKIHKOBL_01854 2.56e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKIHKOBL_01855 1.87e-120 lytE - - M - - - LysM domain protein
NKIHKOBL_01856 5.49e-123 isaA - - M - - - Immunodominant staphylococcal antigen A
NKIHKOBL_01857 0.0 - - - S - - - Bacterial membrane protein, YfhO
NKIHKOBL_01858 1.62e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NKIHKOBL_01859 1.46e-101 - - - F - - - NUDIX domain
NKIHKOBL_01860 1.53e-152 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NKIHKOBL_01861 1.71e-284 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NKIHKOBL_01862 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NKIHKOBL_01863 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NKIHKOBL_01864 1.29e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NKIHKOBL_01865 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
NKIHKOBL_01866 5.92e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKIHKOBL_01867 2.05e-09 - - - - - - - -
NKIHKOBL_01868 7.97e-73 XK27_04840 - - M ko:K08987 - ko00000 Membrane
NKIHKOBL_01869 3.98e-124 XK27_06935 - - K - - - transcriptional regulator
NKIHKOBL_01870 5.13e-270 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NKIHKOBL_01871 7.22e-121 - - - S - - - Putative adhesin
NKIHKOBL_01872 5.59e-29 - - - S - - - Protein of unknown function (DUF1700)
NKIHKOBL_01873 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
NKIHKOBL_01874 4.32e-33 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
NKIHKOBL_01875 1.3e-26 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
NKIHKOBL_01876 2.9e-18 XK27_06885 - - L - - - hydrolase
NKIHKOBL_01877 1.17e-34 - - - K - - - CsbD-like
NKIHKOBL_01878 7.56e-116 - - - M - - - Protein conserved in bacteria
NKIHKOBL_01879 7.53e-33 - - - S - - - Small integral membrane protein
NKIHKOBL_01880 4.42e-130 - - - - - - - -
NKIHKOBL_01881 7.98e-45 ytgB - - S - - - Membrane
NKIHKOBL_01883 8.43e-124 - - - S - - - Hydrophobic domain protein
NKIHKOBL_01884 1.04e-103 yegS - - I - - - Diacylglycerol kinase
NKIHKOBL_01885 1.68e-55 yegS - - I - - - Diacylglycerol kinase
NKIHKOBL_01888 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NKIHKOBL_01889 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NKIHKOBL_01890 2.42e-45 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NKIHKOBL_01891 9.64e-171 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NKIHKOBL_01892 6.78e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NKIHKOBL_01894 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NKIHKOBL_01895 5.96e-213 XK27_01785 - - S - - - cog cog1284
NKIHKOBL_01896 4.85e-189 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NKIHKOBL_01897 1.26e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NKIHKOBL_01898 1.31e-118 - - - K - - - acetyltransferase
NKIHKOBL_01899 7.68e-20 - - - - - - - -
NKIHKOBL_01900 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NKIHKOBL_01901 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
NKIHKOBL_01902 2.7e-62 yrzB - - S - - - Belongs to the UPF0473 family
NKIHKOBL_01903 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKIHKOBL_01904 3.4e-59 yrzL - - S - - - Belongs to the UPF0297 family
NKIHKOBL_01905 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NKIHKOBL_01906 3.74e-303 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
NKIHKOBL_01908 1.74e-169 - - - L - - - Belongs to the 'phage' integrase family
NKIHKOBL_01909 1.59e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
NKIHKOBL_01910 5.53e-79 - - - K - - - sequence-specific DNA binding
NKIHKOBL_01911 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
NKIHKOBL_01912 5.44e-199 - - - C ko:K06871 - ko00000 Radical SAM
NKIHKOBL_01913 6.96e-67 - - - C ko:K06871 - ko00000 Radical SAM
NKIHKOBL_01915 2.7e-164 Z012_04635 - - K - - - sequence-specific DNA binding
NKIHKOBL_01916 1.98e-17 - - - K - - - Transcriptional activator, Rgg GadR MutR family
NKIHKOBL_01917 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
NKIHKOBL_01918 0.0 - - - KLT - - - serine threonine protein kinase
NKIHKOBL_01919 7.46e-200 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)