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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKFGBFPE_00001	6.17e-202	-	-	-	-	-	-	-	-
HKFGBFPE_00002	9.03e-313	-	-	-	M	-	-	-	Glycosyl transferase
HKFGBFPE_00003	1.85e-288	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HKFGBFPE_00004	6.61e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKFGBFPE_00005	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKFGBFPE_00006	4.98e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HKFGBFPE_00007	2.68e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HKFGBFPE_00008	3.1e-113	-	-	-	Q	-	-	-	Methyltransferase
HKFGBFPE_00009	5.41e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKFGBFPE_00010	1.1e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKFGBFPE_00011	1.13e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKFGBFPE_00012	1.44e-121	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKFGBFPE_00013	1.67e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKFGBFPE_00014	6.66e-177	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKFGBFPE_00015	1.03e-209	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKFGBFPE_00016	2.08e-50	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKFGBFPE_00017	1.26e-64	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKFGBFPE_00018	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKFGBFPE_00019	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HKFGBFPE_00020	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HKFGBFPE_00021	1.05e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HKFGBFPE_00022	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HKFGBFPE_00023	1.95e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HKFGBFPE_00024	7.04e-288	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKFGBFPE_00025	5.36e-97	-	-	-	-	-	-	-	-
HKFGBFPE_00026	1.75e-31	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKFGBFPE_00027	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKFGBFPE_00029	9.91e-219	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HKFGBFPE_00030	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HKFGBFPE_00031	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKFGBFPE_00032	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKFGBFPE_00033	2.95e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKFGBFPE_00034	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKFGBFPE_00035	2.31e-131	-	-	-	-	-	-	-	-
HKFGBFPE_00036	4.46e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKFGBFPE_00038	3.62e-308	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKFGBFPE_00039	4.72e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HKFGBFPE_00040	8.71e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKFGBFPE_00041	5.46e-315	-	-	-	E	-	-	-	amino acid
HKFGBFPE_00042	1.64e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HKFGBFPE_00043	4.39e-94	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HKFGBFPE_00044	7.48e-69	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HKFGBFPE_00045	1.1e-06	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HKFGBFPE_00046	5.12e-126	-	-	-	-	-	-	-	-
HKFGBFPE_00047	2.97e-105	-	-	-	L	-	-	-	AAA domain
HKFGBFPE_00048	3.27e-125	-	-	-	L	-	-	-	AAA ATPase domain
HKFGBFPE_00049	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKFGBFPE_00050	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKFGBFPE_00051	4.83e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKFGBFPE_00052	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKFGBFPE_00053	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKFGBFPE_00054	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKFGBFPE_00055	1.27e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKFGBFPE_00056	1.3e-99	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKFGBFPE_00057	1.38e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKFGBFPE_00058	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKFGBFPE_00059	7.2e-185	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKFGBFPE_00060	9.73e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKFGBFPE_00061	4.25e-172	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKFGBFPE_00068	7.11e-57	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HKFGBFPE_00069	5.07e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKFGBFPE_00070	2.7e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKFGBFPE_00071	3.57e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKFGBFPE_00072	5.57e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKFGBFPE_00073	5.02e-29	-	-	-	-	-	-	-	-
HKFGBFPE_00074	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HKFGBFPE_00075	2.16e-202	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKFGBFPE_00076	1.37e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKFGBFPE_00078	3.01e-63	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_00079	3.83e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKFGBFPE_00080	3.7e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKFGBFPE_00081	2.96e-115	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HKFGBFPE_00082	1.42e-126	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKFGBFPE_00083	5.13e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKFGBFPE_00084	8.37e-231	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKFGBFPE_00085	3.06e-28	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKFGBFPE_00086	6.88e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HKFGBFPE_00087	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKFGBFPE_00088	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKFGBFPE_00089	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKFGBFPE_00090	7.79e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKFGBFPE_00091	2.62e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKFGBFPE_00092	1.11e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKFGBFPE_00093	6.66e-151	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKFGBFPE_00094	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKFGBFPE_00095	2.77e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKFGBFPE_00096	3.19e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKFGBFPE_00097	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKFGBFPE_00098	1.56e-20	-	-	-	K	-	-	-	LysR substrate binding domain
HKFGBFPE_00099	1.3e-156	-	-	-	K	ko:K09681	-	ko00000,ko03000	DNA-binding transcription factor activity
HKFGBFPE_00100	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HKFGBFPE_00101	6.03e-196	-	-	-	E	-	-	-	AzlC protein
HKFGBFPE_00102	1.36e-266	hpk31	-	-	T	-	-	-	Histidine kinase
HKFGBFPE_00103	9.76e-161	vanR	-	-	K	-	-	-	response regulator
HKFGBFPE_00104	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKFGBFPE_00105	2.28e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HKFGBFPE_00106	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HKFGBFPE_00107	4.23e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HKFGBFPE_00108	9.76e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKFGBFPE_00109	6.58e-152	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKFGBFPE_00110	6.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKFGBFPE_00111	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKFGBFPE_00112	8.24e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKFGBFPE_00113	3.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKFGBFPE_00114	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKFGBFPE_00115	3.57e-198	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKFGBFPE_00116	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKFGBFPE_00117	1.08e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HKFGBFPE_00118	2.47e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKFGBFPE_00119	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HKFGBFPE_00120	2.25e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKFGBFPE_00121	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKFGBFPE_00123	8.77e-282	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HKFGBFPE_00124	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKFGBFPE_00125	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKFGBFPE_00126	6.44e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HKFGBFPE_00128	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKFGBFPE_00129	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKFGBFPE_00130	9.4e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKFGBFPE_00131	3.9e-40	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKFGBFPE_00132	1.25e-142	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKFGBFPE_00133	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKFGBFPE_00134	2.51e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
HKFGBFPE_00135	9.06e-151	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKFGBFPE_00136	1.52e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKFGBFPE_00137	4.28e-225	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKFGBFPE_00138	2.24e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKFGBFPE_00139	2.23e-150	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HKFGBFPE_00140	6.39e-73	-	-	-	-	-	-	-	-
HKFGBFPE_00144	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKFGBFPE_00146	9.88e-239	-	-	-	-	-	-	-	-
HKFGBFPE_00147	7.82e-37	-	-	-	-	-	-	-	-
HKFGBFPE_00148	7.77e-196	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HKFGBFPE_00149	2.66e-156	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKFGBFPE_00150	5.83e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKFGBFPE_00151	5.2e-89	-	-	-	-	-	-	-	-
HKFGBFPE_00152	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKFGBFPE_00153	1.24e-136	-	-	-	L	-	-	-	nuclease
HKFGBFPE_00154	8.53e-95	-	-	-	-	-	-	-	-
HKFGBFPE_00155	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKFGBFPE_00156	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKFGBFPE_00157	0.0	-	-	-	M	-	-	-	domain protein
HKFGBFPE_00158	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKFGBFPE_00159	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKFGBFPE_00160	5.09e-162	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKFGBFPE_00161	3.84e-60	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HKFGBFPE_00162	2.4e-231	-	-	-	-	-	-	-	-
HKFGBFPE_00163	7.69e-100	-	-	-	-	-	-	-	-
HKFGBFPE_00164	5.16e-115	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKFGBFPE_00166	9.17e-59	-	-	-	-	-	-	-	-
HKFGBFPE_00168	5.67e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKFGBFPE_00169	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKFGBFPE_00170	1.08e-221	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKFGBFPE_00171	2.08e-208	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HKFGBFPE_00172	3.15e-113	-	-	-	C	-	-	-	Flavodoxin
HKFGBFPE_00173	9.07e-106	-	-	-	S	-	-	-	Cupin domain
HKFGBFPE_00174	1.35e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
HKFGBFPE_00175	5.01e-310	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKFGBFPE_00176	6.86e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HKFGBFPE_00177	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HKFGBFPE_00178	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HKFGBFPE_00179	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKFGBFPE_00180	3.82e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKFGBFPE_00181	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKFGBFPE_00182	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HKFGBFPE_00183	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKFGBFPE_00184	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HKFGBFPE_00185	2.28e-137	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKFGBFPE_00186	3.74e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
HKFGBFPE_00187	1.3e-265	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HKFGBFPE_00188	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HKFGBFPE_00189	3.61e-61	-	-	-	-	-	-	-	-
HKFGBFPE_00190	4.83e-312	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKFGBFPE_00191	3.65e-114	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKFGBFPE_00192	1.14e-27	-	-	-	-	-	-	-	-
HKFGBFPE_00193	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HKFGBFPE_00194	4.16e-180	-	-	-	S	-	-	-	Membrane
HKFGBFPE_00195	1.24e-182	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKFGBFPE_00196	2.19e-116	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKFGBFPE_00197	1.66e-286	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKFGBFPE_00198	1.93e-208	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKFGBFPE_00199	2.83e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKFGBFPE_00200	4.87e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKFGBFPE_00201	2.29e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HKFGBFPE_00202	2.42e-201	yeaE	-	-	S	-	-	-	Aldo keto
HKFGBFPE_00203	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKFGBFPE_00204	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HKFGBFPE_00205	7.91e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKFGBFPE_00206	2.05e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKFGBFPE_00207	7.03e-33	-	-	-	-	-	-	-	-
HKFGBFPE_00208	2.01e-134	-	-	-	V	-	-	-	VanZ like family
HKFGBFPE_00209	8.53e-304	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKFGBFPE_00210	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKFGBFPE_00211	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_00212	1.48e-31	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HKFGBFPE_00213	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKFGBFPE_00214	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKFGBFPE_00215	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKFGBFPE_00216	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKFGBFPE_00217	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKFGBFPE_00218	6.71e-102	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKFGBFPE_00219	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKFGBFPE_00220	3.59e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKFGBFPE_00221	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKFGBFPE_00222	2.05e-282	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKFGBFPE_00223	2.71e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKFGBFPE_00224	9.11e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKFGBFPE_00225	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKFGBFPE_00226	6.38e-159	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HKFGBFPE_00227	3.85e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKFGBFPE_00228	5.46e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKFGBFPE_00229	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKFGBFPE_00230	8.76e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKFGBFPE_00231	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKFGBFPE_00232	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_00235	3.61e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
HKFGBFPE_00236	6.94e-238	-	-	-	-	-	-	-	-
HKFGBFPE_00237	8.42e-204	-	-	-	-	-	-	-	-
HKFGBFPE_00238	7.62e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKFGBFPE_00239	6.94e-132	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKFGBFPE_00240	1.51e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKFGBFPE_00241	1.28e-18	-	-	-	-	-	-	-	-
HKFGBFPE_00242	1.31e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKFGBFPE_00243	1.14e-158	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKFGBFPE_00244	1.02e-196	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKFGBFPE_00245	2.23e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKFGBFPE_00246	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKFGBFPE_00247	2.73e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKFGBFPE_00248	2.62e-67	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKFGBFPE_00249	4.05e-124	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKFGBFPE_00250	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKFGBFPE_00251	1.14e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKFGBFPE_00253	2.58e-154	-	-	-	H	-	-	-	RibD C-terminal domain
HKFGBFPE_00254	5.46e-207	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKFGBFPE_00255	5.77e-291	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKFGBFPE_00256	6.2e-155	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKFGBFPE_00257	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HKFGBFPE_00258	1.15e-15	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HKFGBFPE_00259	1.24e-83	-	-	-	C	-	-	-	Flavodoxin
HKFGBFPE_00260	2.39e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HKFGBFPE_00261	9.91e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKFGBFPE_00262	7.57e-206	-	-	-	-	-	-	-	-
HKFGBFPE_00263	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HKFGBFPE_00264	3.99e-109	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKFGBFPE_00265	5.63e-198	-	-	-	EG	-	-	-	EamA-like transporter family
HKFGBFPE_00266	1.15e-152	-	-	-	L	-	-	-	Integrase
HKFGBFPE_00267	2.95e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HKFGBFPE_00268	1.26e-55	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKFGBFPE_00269	2.45e-110	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKFGBFPE_00270	2.98e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HKFGBFPE_00271	4.7e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKFGBFPE_00272	7.96e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKFGBFPE_00273	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKFGBFPE_00274	7.7e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKFGBFPE_00275	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HKFGBFPE_00276	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HKFGBFPE_00277	3.34e-55	-	-	-	O	-	-	-	Bacterial dnaA protein
HKFGBFPE_00278	1.4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKFGBFPE_00279	5.43e-191	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
HKFGBFPE_00280	4.42e-216	-	-	-	C	-	-	-	Aldo keto reductase
HKFGBFPE_00281	1.29e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKFGBFPE_00282	9.94e-176	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKFGBFPE_00283	1.94e-49	-	-	-	S	-	-	-	Double zinc ribbon
HKFGBFPE_00284	1.19e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKFGBFPE_00285	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HKFGBFPE_00286	3.14e-177	-	-	-	IQ	-	-	-	KR domain
HKFGBFPE_00287	7.29e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKFGBFPE_00288	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKFGBFPE_00289	1.91e-313	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_00290	2.39e-146	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKFGBFPE_00291	6.5e-71	-	-	-	-	-	-	-	-
HKFGBFPE_00292	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKFGBFPE_00293	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKFGBFPE_00294	1.25e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKFGBFPE_00295	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_00296	7.82e-204	-	-	-	-	-	-	-	-
HKFGBFPE_00297	1.76e-233	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKFGBFPE_00298	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HKFGBFPE_00299	2.77e-270	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_00300	1.97e-99	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKFGBFPE_00301	5.65e-19	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKFGBFPE_00302	7.21e-88	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKFGBFPE_00303	1.48e-18	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKFGBFPE_00304	2.52e-65	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKFGBFPE_00307	9e-72	-	-	-	-	-	-	-	-
HKFGBFPE_00308	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKFGBFPE_00309	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKFGBFPE_00310	1.14e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKFGBFPE_00311	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKFGBFPE_00312	1.81e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKFGBFPE_00313	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKFGBFPE_00314	5.19e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKFGBFPE_00315	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKFGBFPE_00316	1.59e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKFGBFPE_00317	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKFGBFPE_00318	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKFGBFPE_00319	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKFGBFPE_00320	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKFGBFPE_00321	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKFGBFPE_00322	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKFGBFPE_00323	1.41e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKFGBFPE_00324	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKFGBFPE_00325	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKFGBFPE_00326	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKFGBFPE_00327	4.22e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKFGBFPE_00328	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKFGBFPE_00329	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKFGBFPE_00330	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKFGBFPE_00331	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKFGBFPE_00332	1.86e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKFGBFPE_00333	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKFGBFPE_00334	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HKFGBFPE_00335	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKFGBFPE_00336	1.51e-94	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_00337	2.26e-65	-	-	-	-	-	-	-	-
HKFGBFPE_00338	7.15e-121	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HKFGBFPE_00339	1.33e-74	-	-	-	S	-	-	-	AAA ATPase domain
HKFGBFPE_00340	3.03e-13	-	-	-	M	-	-	-	LysM domain
HKFGBFPE_00344	3.01e-42	-	-	-	-	-	-	-	-
HKFGBFPE_00345	8.01e-08	-	-	-	E	-	-	-	Pfam:DUF955
HKFGBFPE_00346	6.11e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKFGBFPE_00347	9.3e-35	-	-	-	-	-	-	-	-
HKFGBFPE_00349	1.14e-82	-	-	-	S	-	-	-	DNA binding
HKFGBFPE_00350	1.25e-10	-	-	-	-	-	-	-	-
HKFGBFPE_00354	2.5e-99	-	-	-	L	-	-	-	DnaD domain protein
HKFGBFPE_00355	1.65e-46	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKFGBFPE_00357	4.17e-30	-	-	-	-	-	-	-	-
HKFGBFPE_00358	1.47e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HKFGBFPE_00363	2.08e-11	-	-	-	-	-	-	-	-
HKFGBFPE_00365	1.77e-91	-	-	-	L	-	-	-	HNH nucleases
HKFGBFPE_00366	1.49e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
HKFGBFPE_00367	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKFGBFPE_00369	1.22e-272	-	-	-	S	-	-	-	Phage portal protein
HKFGBFPE_00370	2.29e-146	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKFGBFPE_00371	2.83e-248	-	-	-	S	-	-	-	Phage capsid family
HKFGBFPE_00372	8.72e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKFGBFPE_00376	1.9e-97	-	-	-	S	-	-	-	Phage tail tube protein
HKFGBFPE_00377	2.92e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HKFGBFPE_00379	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HKFGBFPE_00380	5.59e-104	-	-	-	S	-	-	-	Phage tail protein
HKFGBFPE_00381	2.78e-174	-	-	-	M	-	-	-	Prophage endopeptidase tail
HKFGBFPE_00385	0.0	-	-	-	L	-	-	-	Transposase
HKFGBFPE_00386	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKFGBFPE_00387	4.04e-283	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HKFGBFPE_00388	1.83e-21	-	-	-	-	-	-	-	-
HKFGBFPE_00390	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKFGBFPE_00391	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKFGBFPE_00392	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKFGBFPE_00393	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKFGBFPE_00394	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKFGBFPE_00395	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKFGBFPE_00396	2.12e-19	-	-	-	-	-	-	-	-
HKFGBFPE_00397	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKFGBFPE_00398	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKFGBFPE_00399	5.98e-116	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HKFGBFPE_00400	5.33e-211	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HKFGBFPE_00401	3.83e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKFGBFPE_00402	2.04e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKFGBFPE_00403	1.12e-214	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HKFGBFPE_00404	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HKFGBFPE_00405	4.49e-178	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HKFGBFPE_00406	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKFGBFPE_00407	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKFGBFPE_00408	4.38e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKFGBFPE_00409	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKFGBFPE_00410	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKFGBFPE_00411	3.65e-67	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HKFGBFPE_00412	2.62e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKFGBFPE_00413	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKFGBFPE_00414	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKFGBFPE_00415	8.07e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKFGBFPE_00416	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKFGBFPE_00417	1.4e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKFGBFPE_00418	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_00419	3.07e-89	-	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_00421	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKFGBFPE_00422	3.29e-183	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKFGBFPE_00423	3e-111	-	-	-	-	-	-	-	-
HKFGBFPE_00424	1.6e-36	-	-	-	-	-	-	-	-
HKFGBFPE_00426	1.39e-142	-	-	-	-	-	-	-	-
HKFGBFPE_00427	1.36e-83	cps3I	-	-	G	-	-	-	Acyltransferase family
HKFGBFPE_00428	1.37e-95	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKFGBFPE_00429	9.95e-58	-	-	-	M	-	-	-	biosynthesis protein
HKFGBFPE_00430	4.63e-119	cps3F	-	-	-	-	-	-	-
HKFGBFPE_00431	1.58e-124	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKFGBFPE_00432	2.56e-140	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKFGBFPE_00433	1.22e-93	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HKFGBFPE_00434	8.02e-271	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKFGBFPE_00435	4.3e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKFGBFPE_00436	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HKFGBFPE_00437	6.98e-40	-	-	-	-	-	-	-	-
HKFGBFPE_00438	2.86e-224	-	-	-	G	-	-	-	Peptidase_C39 like family
HKFGBFPE_00439	6.92e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKFGBFPE_00440	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKFGBFPE_00441	9.87e-300	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKFGBFPE_00442	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKFGBFPE_00443	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKFGBFPE_00444	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKFGBFPE_00445	3.54e-276	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKFGBFPE_00446	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKFGBFPE_00447	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HKFGBFPE_00448	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKFGBFPE_00449	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKFGBFPE_00450	1.48e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKFGBFPE_00451	4.14e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKFGBFPE_00452	3.61e-84	-	-	-	-	-	-	-	-
HKFGBFPE_00453	2.27e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKFGBFPE_00454	2.83e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKFGBFPE_00455	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKFGBFPE_00456	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKFGBFPE_00457	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKFGBFPE_00458	4.55e-288	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_00459	1.7e-182	-	-	-	-	-	-	-	-
HKFGBFPE_00460	4.29e-18	-	-	-	-	-	-	-	-
HKFGBFPE_00461	2.44e-99	-	-	-	-	-	-	-	-
HKFGBFPE_00462	5.09e-107	-	-	-	-	-	-	-	-
HKFGBFPE_00463	2.6e-14	-	-	-	K	-	-	-	Peptidase S24-like
HKFGBFPE_00464	1.21e-30	-	-	-	K	-	-	-	Peptidase S24-like
HKFGBFPE_00465	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKFGBFPE_00466	3.16e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKFGBFPE_00467	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKFGBFPE_00469	3.36e-77	-	-	-	-	-	-	-	-
HKFGBFPE_00470	2.15e-234	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKFGBFPE_00471	1.05e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKFGBFPE_00472	2.38e-72	-	-	-	-	-	-	-	-
HKFGBFPE_00473	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKFGBFPE_00474	2.19e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKFGBFPE_00475	1.54e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HKFGBFPE_00476	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKFGBFPE_00477	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_00478	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKFGBFPE_00479	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKFGBFPE_00480	1.58e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKFGBFPE_00481	9.82e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKFGBFPE_00482	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKFGBFPE_00483	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKFGBFPE_00484	7.24e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKFGBFPE_00485	1.49e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKFGBFPE_00486	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKFGBFPE_00487	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKFGBFPE_00488	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKFGBFPE_00489	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKFGBFPE_00490	1.24e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKFGBFPE_00491	7.41e-180	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKFGBFPE_00492	3.31e-206	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKFGBFPE_00493	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKFGBFPE_00494	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKFGBFPE_00495	5.28e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKFGBFPE_00496	3.86e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKFGBFPE_00497	4.96e-307	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKFGBFPE_00498	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKFGBFPE_00499	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HKFGBFPE_00500	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKFGBFPE_00501	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKFGBFPE_00502	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKFGBFPE_00503	9.18e-83	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HKFGBFPE_00504	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HKFGBFPE_00505	2.07e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HKFGBFPE_00506	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKFGBFPE_00507	1.81e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HKFGBFPE_00508	4.12e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKFGBFPE_00510	0.0	-	-	-	L	-	-	-	PLD-like domain
HKFGBFPE_00511	1.27e-82	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HKFGBFPE_00512	1.31e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKFGBFPE_00513	5.41e-73	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HKFGBFPE_00514	4.45e-47	-	-	-	-	-	-	-	-
HKFGBFPE_00515	3.46e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKFGBFPE_00516	7.32e-124	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKFGBFPE_00517	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKFGBFPE_00518	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKFGBFPE_00519	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKFGBFPE_00520	8.74e-235	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFGBFPE_00521	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HKFGBFPE_00522	2.92e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKFGBFPE_00523	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKFGBFPE_00524	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKFGBFPE_00525	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HKFGBFPE_00526	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKFGBFPE_00527	1.49e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKFGBFPE_00528	3.18e-167	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKFGBFPE_00530	1.15e-21	-	-	-	-	-	-	-	-
HKFGBFPE_00531	8.38e-26	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKFGBFPE_00532	4.17e-282	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HKFGBFPE_00533	3.06e-179	-	-	-	S	-	-	-	Phage portal protein
HKFGBFPE_00534	5.53e-253	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKFGBFPE_00535	5.12e-30	terS	-	-	L	-	-	-	Phage terminase, small subunit
HKFGBFPE_00536	3.27e-30	-	-	-	L	-	-	-	HNH endonuclease
HKFGBFPE_00539	5.36e-108	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HKFGBFPE_00540	2.28e-45	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HKFGBFPE_00544	7.1e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
HKFGBFPE_00545	8.09e-09	-	-	-	S	-	-	-	Helix-turn-helix domain
HKFGBFPE_00547	1.68e-65	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_00548	7.41e-130	-	-	-	-	-	-	-	-
HKFGBFPE_00549	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKFGBFPE_00550	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKFGBFPE_00551	1.75e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFGBFPE_00552	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKFGBFPE_00553	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKFGBFPE_00554	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKFGBFPE_00555	2.44e-20	-	-	-	-	-	-	-	-
HKFGBFPE_00556	1.41e-84	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKFGBFPE_00557	1.24e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKFGBFPE_00558	5.03e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKFGBFPE_00559	1.25e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKFGBFPE_00560	2.15e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKFGBFPE_00561	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKFGBFPE_00562	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKFGBFPE_00563	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKFGBFPE_00564	2.27e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKFGBFPE_00565	4.23e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKFGBFPE_00566	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKFGBFPE_00567	2.37e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKFGBFPE_00568	1.57e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKFGBFPE_00569	1.18e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKFGBFPE_00570	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKFGBFPE_00571	1.6e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
HKFGBFPE_00572	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKFGBFPE_00573	2.15e-83	-	-	-	M	-	-	-	Lysin motif
HKFGBFPE_00574	5.39e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKFGBFPE_00575	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKFGBFPE_00576	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKFGBFPE_00577	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKFGBFPE_00578	1.16e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKFGBFPE_00579	2.55e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKFGBFPE_00580	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_00581	1.26e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKFGBFPE_00582	4.1e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKFGBFPE_00583	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKFGBFPE_00584	4.49e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKFGBFPE_00585	4.59e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKFGBFPE_00586	2.85e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HKFGBFPE_00587	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKFGBFPE_00588	1.46e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKFGBFPE_00589	9.06e-184	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKFGBFPE_00590	6.71e-208	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKFGBFPE_00591	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKFGBFPE_00592	1.66e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKFGBFPE_00593	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKFGBFPE_00594	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKFGBFPE_00595	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKFGBFPE_00596	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
HKFGBFPE_00597	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKFGBFPE_00598	2.59e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HKFGBFPE_00599	9.14e-66	-	-	-	-	-	-	-	-
HKFGBFPE_00601	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKFGBFPE_00602	8.08e-83	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKFGBFPE_00603	1.04e-33	-	-	-	-	-	-	-	-
HKFGBFPE_00604	1.89e-123	-	-	-	-	-	-	-	-
HKFGBFPE_00605	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKFGBFPE_00606	2.04e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKFGBFPE_00607	3.78e-215	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HKFGBFPE_00609	1.78e-210	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HKFGBFPE_00610	1.04e-149	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
HKFGBFPE_00611	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_00612	2.49e-82	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKFGBFPE_00613	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKFGBFPE_00614	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKFGBFPE_00615	1.48e-178	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HKFGBFPE_00616	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKFGBFPE_00617	1.26e-60	-	-	-	-	-	-	-	-
HKFGBFPE_00618	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HKFGBFPE_00619	2.58e-41	-	-	-	-	-	-	-	-
HKFGBFPE_00620	3.8e-63	-	-	-	-	-	-	-	-
HKFGBFPE_00621	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKFGBFPE_00622	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKFGBFPE_00623	3.2e-57	-	-	-	L	-	-	-	Integrase core domain
HKFGBFPE_00624	1.37e-243	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HKFGBFPE_00625	1.77e-230	yueF	-	-	S	-	-	-	AI-2E family transporter
HKFGBFPE_00626	2.57e-32	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HKFGBFPE_00628	7.53e-191	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HKFGBFPE_00629	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKFGBFPE_00630	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKFGBFPE_00631	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKFGBFPE_00632	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKFGBFPE_00633	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFGBFPE_00634	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFGBFPE_00635	3.31e-263	-	-	-	-	-	-	-	-
HKFGBFPE_00636	1.44e-155	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKFGBFPE_00637	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKFGBFPE_00638	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKFGBFPE_00639	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKFGBFPE_00640	2.58e-254	-	-	-	L	-	-	-	Transposase
HKFGBFPE_00641	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKFGBFPE_00642	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKFGBFPE_00643	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKFGBFPE_00644	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKFGBFPE_00645	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKFGBFPE_00646	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKFGBFPE_00647	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKFGBFPE_00648	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKFGBFPE_00649	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKFGBFPE_00650	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKFGBFPE_00651	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKFGBFPE_00652	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKFGBFPE_00653	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKFGBFPE_00654	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKFGBFPE_00655	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKFGBFPE_00656	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKFGBFPE_00657	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKFGBFPE_00658	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKFGBFPE_00659	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKFGBFPE_00660	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKFGBFPE_00661	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKFGBFPE_00662	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKFGBFPE_00663	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKFGBFPE_00664	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKFGBFPE_00665	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKFGBFPE_00666	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKFGBFPE_00667	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFGBFPE_00668	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKFGBFPE_00669	2.21e-189	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFGBFPE_00670	2.14e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFGBFPE_00671	5.82e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFGBFPE_00672	1.23e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKFGBFPE_00673	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKFGBFPE_00674	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKFGBFPE_00675	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HKFGBFPE_00676	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKFGBFPE_00677	4.76e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKFGBFPE_00678	3.24e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKFGBFPE_00679	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKFGBFPE_00680	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKFGBFPE_00681	9.09e-260	camS	-	-	S	-	-	-	sex pheromone
HKFGBFPE_00682	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKFGBFPE_00683	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKFGBFPE_00684	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKFGBFPE_00685	2.72e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKFGBFPE_00687	5.1e-45	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HKFGBFPE_00688	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKFGBFPE_00689	2.79e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKFGBFPE_00690	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKFGBFPE_00691	3.24e-16	-	-	-	-	-	-	-	-
HKFGBFPE_00694	9.72e-77	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKFGBFPE_00695	4.51e-285	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKFGBFPE_00696	1.62e-66	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKFGBFPE_00697	7.66e-255	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_00698	8.53e-120	ymdB	-	-	S	-	-	-	Macro domain protein
HKFGBFPE_00699	1.03e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKFGBFPE_00700	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKFGBFPE_00701	4.23e-64	-	-	-	-	-	-	-	-
HKFGBFPE_00702	2.59e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
HKFGBFPE_00703	3.49e-269	-	-	-	S	-	-	-	associated with various cellular activities
HKFGBFPE_00704	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKFGBFPE_00705	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKFGBFPE_00707	2.8e-159	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HKFGBFPE_00708	8.14e-73	-	-	-	-	-	-	-	-
HKFGBFPE_00710	3.19e-182	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKFGBFPE_00711	2.48e-66	-	-	-	-	-	-	-	-
HKFGBFPE_00712	5.51e-264	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HKFGBFPE_00713	2.81e-297	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKFGBFPE_00714	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKFGBFPE_00715	1.79e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HKFGBFPE_00716	1.57e-190	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKFGBFPE_00717	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKFGBFPE_00720	1.15e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HKFGBFPE_00721	3.01e-19	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKFGBFPE_00723	5.43e-179	-	-	-	M	-	-	-	PFAM NLP P60 protein
HKFGBFPE_00724	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKFGBFPE_00725	6.8e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKFGBFPE_00726	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_00727	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
HKFGBFPE_00728	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKFGBFPE_00729	1.94e-305	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKFGBFPE_00730	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKFGBFPE_00731	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HKFGBFPE_00732	4.92e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKFGBFPE_00733	6.47e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKFGBFPE_00734	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKFGBFPE_00735	2.77e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKFGBFPE_00738	2.88e-229	-	-	-	-	-	-	-	-
HKFGBFPE_00739	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKFGBFPE_00740	2.88e-310	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKFGBFPE_00741	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKFGBFPE_00742	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKFGBFPE_00743	3.24e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKFGBFPE_00744	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKFGBFPE_00745	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFGBFPE_00746	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFGBFPE_00747	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFGBFPE_00748	2.04e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKFGBFPE_00749	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKFGBFPE_00750	1.18e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKFGBFPE_00751	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKFGBFPE_00752	2.87e-96	-	-	-	-	-	-	-	-
HKFGBFPE_00753	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKFGBFPE_00754	4.57e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKFGBFPE_00755	3.47e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKFGBFPE_00756	5.02e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HKFGBFPE_00757	3.28e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKFGBFPE_00758	8.21e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKFGBFPE_00759	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKFGBFPE_00760	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKFGBFPE_00761	3.58e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKFGBFPE_00762	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKFGBFPE_00763	1.77e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKFGBFPE_00764	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKFGBFPE_00765	9.18e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HKFGBFPE_00767	1.51e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKFGBFPE_00768	1.33e-228	-	-	-	-	-	-	-	-
HKFGBFPE_00769	3.28e-296	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKFGBFPE_00770	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKFGBFPE_00771	1.3e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKFGBFPE_00772	6.68e-238	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HKFGBFPE_00773	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HKFGBFPE_00774	0.0	-	-	-	L	-	-	-	DNA helicase
HKFGBFPE_00775	1.57e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKFGBFPE_00777	8.93e-31	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKFGBFPE_00778	1.09e-244	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKFGBFPE_00779	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HKFGBFPE_00780	8.11e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKFGBFPE_00781	9.57e-52	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HKFGBFPE_00782	1.63e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HKFGBFPE_00783	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKFGBFPE_00784	1.45e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKFGBFPE_00785	1.04e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKFGBFPE_00786	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_00787	6.12e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKFGBFPE_00788	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKFGBFPE_00789	1.05e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKFGBFPE_00790	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HKFGBFPE_00791	4.13e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_00792	4.69e-136	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_00793	5.3e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HKFGBFPE_00794	1.11e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_00795	6.39e-198	-	-	-	GM	-	-	-	NAD(P)H-binding
HKFGBFPE_00796	4.44e-11	-	-	-	-	-	-	-	-
HKFGBFPE_00797	6.49e-288	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HKFGBFPE_00798	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKFGBFPE_00799	8.61e-167	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HKFGBFPE_00800	1.11e-131	-	-	-	-	-	-	-	-
HKFGBFPE_00801	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKFGBFPE_00802	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HKFGBFPE_00804	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKFGBFPE_00805	3.6e-107	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HKFGBFPE_00806	5.05e-232	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKFGBFPE_00808	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKFGBFPE_00809	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HKFGBFPE_00810	2.5e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HKFGBFPE_00812	9.76e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKFGBFPE_00813	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKFGBFPE_00814	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HKFGBFPE_00815	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKFGBFPE_00816	2.33e-51	-	-	-	-	-	-	-	-
HKFGBFPE_00817	1.89e-171	-	-	-	IQ	-	-	-	dehydrogenase reductase
HKFGBFPE_00818	1.64e-142	-	-	-	-	-	-	-	-
HKFGBFPE_00819	2e-67	isp	-	-	L	-	-	-	Transposase
HKFGBFPE_00820	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HKFGBFPE_00821	4.91e-171	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKFGBFPE_00822	9.81e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKFGBFPE_00823	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HKFGBFPE_00824	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKFGBFPE_00825	8.49e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKFGBFPE_00826	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKFGBFPE_00827	2.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKFGBFPE_00828	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKFGBFPE_00829	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKFGBFPE_00830	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKFGBFPE_00831	1.03e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKFGBFPE_00832	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKFGBFPE_00833	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKFGBFPE_00834	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKFGBFPE_00835	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKFGBFPE_00836	6.8e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_00837	1.56e-80	-	-	-	-	-	-	-	-
HKFGBFPE_00838	1.36e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HKFGBFPE_00839	9.45e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HKFGBFPE_00840	1.21e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HKFGBFPE_00841	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HKFGBFPE_00842	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKFGBFPE_00843	2.54e-243	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HKFGBFPE_00844	4.94e-109	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HKFGBFPE_00845	1.27e-290	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HKFGBFPE_00846	1.17e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HKFGBFPE_00847	2.03e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKFGBFPE_00848	1.56e-60	-	-	-	-	-	-	-	-
HKFGBFPE_00849	5.31e-242	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HKFGBFPE_00850	7.45e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HKFGBFPE_00851	2.45e-26	-	-	-	-	-	-	-	-
HKFGBFPE_00852	2.71e-234	-	-	-	-	-	-	-	-
HKFGBFPE_00853	3.34e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
HKFGBFPE_00854	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HKFGBFPE_00855	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HKFGBFPE_00856	8.67e-85	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HKFGBFPE_00857	1.21e-99	-	-	-	S	-	-	-	Flavodoxin
HKFGBFPE_00858	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKFGBFPE_00859	3.12e-176	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKFGBFPE_00860	2.74e-222	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKFGBFPE_00861	1.65e-151	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKFGBFPE_00862	1.77e-93	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKFGBFPE_00863	6.83e-101	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKFGBFPE_00864	6.85e-115	-	-	-	-	-	-	-	-
HKFGBFPE_00865	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKFGBFPE_00866	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKFGBFPE_00867	2.77e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKFGBFPE_00868	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKFGBFPE_00869	5.23e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKFGBFPE_00870	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKFGBFPE_00871	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HKFGBFPE_00872	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKFGBFPE_00873	4.11e-52	yabO	-	-	J	-	-	-	S4 domain protein
HKFGBFPE_00874	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKFGBFPE_00875	1.38e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKFGBFPE_00876	8.08e-147	-	-	-	S	-	-	-	(CBS) domain
HKFGBFPE_00877	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKFGBFPE_00878	9.6e-310	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HKFGBFPE_00879	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKFGBFPE_00880	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKFGBFPE_00881	2.28e-271	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKFGBFPE_00882	2.29e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKFGBFPE_00883	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKFGBFPE_00884	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKFGBFPE_00885	1.91e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKFGBFPE_00886	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKFGBFPE_00887	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKFGBFPE_00888	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HKFGBFPE_00889	5.47e-55	-	-	-	S	-	-	-	Cytochrome B5
HKFGBFPE_00890	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HKFGBFPE_00891	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HKFGBFPE_00892	7.65e-101	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HKFGBFPE_00893	6.67e-158	-	-	-	GM	-	-	-	NmrA-like family
HKFGBFPE_00894	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKFGBFPE_00895	1.41e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HKFGBFPE_00896	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKFGBFPE_00897	2.05e-294	-	-	-	-	-	-	-	-
HKFGBFPE_00898	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKFGBFPE_00899	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKFGBFPE_00900	3.31e-137	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HKFGBFPE_00901	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKFGBFPE_00902	7.58e-63	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_00903	4.39e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKFGBFPE_00904	2.03e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKFGBFPE_00905	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKFGBFPE_00906	2.64e-169	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKFGBFPE_00907	5.29e-170	-	-	-	-	-	-	-	-
HKFGBFPE_00909	3.64e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HKFGBFPE_00911	9.68e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKFGBFPE_00912	7.17e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKFGBFPE_00914	3.99e-196	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKFGBFPE_00915	1.53e-38	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKFGBFPE_00916	1.57e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HKFGBFPE_00917	0.0	yagE	-	-	E	-	-	-	amino acid
HKFGBFPE_00918	4.86e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKFGBFPE_00919	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKFGBFPE_00920	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HKFGBFPE_00921	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKFGBFPE_00922	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKFGBFPE_00923	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKFGBFPE_00924	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKFGBFPE_00925	1.52e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKFGBFPE_00926	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKFGBFPE_00927	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKFGBFPE_00928	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKFGBFPE_00929	5.84e-203	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKFGBFPE_00930	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKFGBFPE_00931	5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKFGBFPE_00932	8.7e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKFGBFPE_00933	5.59e-54	-	-	-	H	-	-	-	RibD C-terminal domain
HKFGBFPE_00934	1.15e-26	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKFGBFPE_00935	3.43e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HKFGBFPE_00936	6.53e-118	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HKFGBFPE_00937	9.8e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKFGBFPE_00938	5.85e-254	flp	-	-	V	-	-	-	Beta-lactamase
HKFGBFPE_00939	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKFGBFPE_00940	2.81e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HKFGBFPE_00941	4.91e-156	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKFGBFPE_00943	3.18e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HKFGBFPE_00944	1.52e-64	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HKFGBFPE_00945	4.61e-155	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HKFGBFPE_00946	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HKFGBFPE_00947	0.0	-	-	-	S	-	-	-	amidohydrolase
HKFGBFPE_00948	1.86e-212	-	-	-	S	-	-	-	reductase
HKFGBFPE_00949	2.55e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HKFGBFPE_00950	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKFGBFPE_00951	1.49e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKFGBFPE_00952	7.74e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKFGBFPE_00953	4.96e-152	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKFGBFPE_00954	5.6e-70	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKFGBFPE_00955	5.88e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKFGBFPE_00956	2.57e-272	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKFGBFPE_00957	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKFGBFPE_00958	5e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKFGBFPE_00959	1.49e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HKFGBFPE_00960	4.84e-233	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKFGBFPE_00963	1.29e-156	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKFGBFPE_00964	2.76e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKFGBFPE_00965	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HKFGBFPE_00966	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HKFGBFPE_00967	1.42e-190	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKFGBFPE_00968	8.88e-48	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKFGBFPE_00969	1.06e-100	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HKFGBFPE_00970	4.34e-200	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_00971	2.48e-58	-	-	-	-	-	-	-	-
HKFGBFPE_00972	3.48e-121	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKFGBFPE_00973	6.12e-71	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKFGBFPE_00974	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HKFGBFPE_00975	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HKFGBFPE_00976	2.13e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKFGBFPE_00977	3.39e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKFGBFPE_00978	4.84e-21	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKFGBFPE_00979	4.43e-13	-	-	-	L	-	-	-	Winged helix-turn helix
HKFGBFPE_00981	3.62e-268	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKFGBFPE_00982	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HKFGBFPE_00983	2.89e-110	yvbK	-	-	K	-	-	-	GNAT family
HKFGBFPE_00984	5.22e-120	-	-	-	-	-	-	-	-
HKFGBFPE_00985	2.24e-160	pnb	-	-	C	-	-	-	nitroreductase
HKFGBFPE_00986	5.29e-109	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HKFGBFPE_00987	2.35e-165	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HKFGBFPE_00988	4.43e-100	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKFGBFPE_00989	1.22e-218	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HKFGBFPE_00990	4.56e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKFGBFPE_00991	2.57e-103	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKFGBFPE_00992	2.44e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKFGBFPE_00993	7.31e-27	-	-	-	-	-	-	-	-
HKFGBFPE_00994	1.59e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKFGBFPE_00995	3.32e-107	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HKFGBFPE_00996	1.32e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HKFGBFPE_00997	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKFGBFPE_00998	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKFGBFPE_00999	1.66e-142	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKFGBFPE_01000	7.97e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HKFGBFPE_01001	1.31e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HKFGBFPE_01002	2.32e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKFGBFPE_01004	8.5e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKFGBFPE_01005	4.96e-73	-	-	-	-	-	-	-	-
HKFGBFPE_01006	2.03e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKFGBFPE_01007	3e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKFGBFPE_01008	8.1e-153	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKFGBFPE_01009	6.12e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
HKFGBFPE_01010	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKFGBFPE_01011	1.37e-147	-	-	-	I	-	-	-	Acid phosphatase homologues
HKFGBFPE_01012	2.61e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKFGBFPE_01013	1.34e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HKFGBFPE_01014	2.33e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKFGBFPE_01016	1.46e-236	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKFGBFPE_01017	9.08e-317	-	-	-	E	ko:K03294	-	ko00000	amino acid
HKFGBFPE_01018	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HKFGBFPE_01019	2.99e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKFGBFPE_01021	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKFGBFPE_01022	2.09e-86	-	-	-	-	-	-	-	-
HKFGBFPE_01023	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKFGBFPE_01024	9.96e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HKFGBFPE_01025	5.75e-117	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HKFGBFPE_01026	2.5e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01027	2.58e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01028	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01029	9.71e-50	-	-	-	-	-	-	-	-
HKFGBFPE_01030	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKFGBFPE_01031	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKFGBFPE_01032	7.96e-223	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKFGBFPE_01033	2.6e-33	-	-	-	-	-	-	-	-
HKFGBFPE_01034	1.03e-146	-	-	-	-	-	-	-	-
HKFGBFPE_01035	5.21e-275	yttB	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_01036	1.61e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKFGBFPE_01037	1.04e-114	-	-	-	-	-	-	-	-
HKFGBFPE_01038	2.13e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HKFGBFPE_01039	1.25e-54	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKFGBFPE_01040	2.75e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKFGBFPE_01041	1.78e-204	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKFGBFPE_01042	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKFGBFPE_01043	5.22e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01044	7.79e-236	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HKFGBFPE_01045	6.91e-164	XK27_10500	-	-	K	-	-	-	response regulator
HKFGBFPE_01046	1.3e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
HKFGBFPE_01047	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKFGBFPE_01048	8.19e-108	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKFGBFPE_01049	2.72e-262	-	-	-	-	-	-	-	-
HKFGBFPE_01050	4.33e-69	-	-	-	-	-	-	-	-
HKFGBFPE_01051	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HKFGBFPE_01052	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
HKFGBFPE_01053	7.67e-223	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HKFGBFPE_01054	1.29e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKFGBFPE_01055	6.03e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKFGBFPE_01056	6.21e-43	-	-	-	-	-	-	-	-
HKFGBFPE_01057	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKFGBFPE_01058	2.14e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKFGBFPE_01059	0.0	potE	-	-	E	-	-	-	Amino Acid
HKFGBFPE_01060	9.04e-90	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HKFGBFPE_01061	1.24e-201	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HKFGBFPE_01062	4.15e-282	arcT	-	-	E	-	-	-	Aminotransferase
HKFGBFPE_01063	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKFGBFPE_01064	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKFGBFPE_01065	1.17e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKFGBFPE_01066	2.15e-121	-	-	-	-	-	-	-	-
HKFGBFPE_01067	8.92e-87	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKFGBFPE_01068	4.05e-221	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKFGBFPE_01069	1.53e-188	epsB	-	-	M	-	-	-	biosynthesis protein
HKFGBFPE_01070	9.45e-158	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKFGBFPE_01071	5.28e-133	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKFGBFPE_01072	3.73e-94	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HKFGBFPE_01073	9.76e-66	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HKFGBFPE_01075	3.87e-32	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKFGBFPE_01076	1.53e-55	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKFGBFPE_01077	4.89e-50	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKFGBFPE_01078	1.7e-26	-	2.4.1.56	GT4,GT9	M	ko:K03280	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HKFGBFPE_01079	2.15e-75	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKFGBFPE_01080	3.38e-106	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKFGBFPE_01081	8.06e-111	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKFGBFPE_01082	1.16e-120	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HKFGBFPE_01083	5.35e-69	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HKFGBFPE_01084	2.13e-142	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HKFGBFPE_01085	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKFGBFPE_01086	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HKFGBFPE_01087	8.22e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKFGBFPE_01088	1.31e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKFGBFPE_01089	8.29e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKFGBFPE_01090	7.1e-226	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKFGBFPE_01091	1.09e-221	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKFGBFPE_01092	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKFGBFPE_01093	8.07e-64	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKFGBFPE_01094	2.91e-33	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKFGBFPE_01095	5e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HKFGBFPE_01096	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
HKFGBFPE_01097	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKFGBFPE_01098	1.21e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKFGBFPE_01099	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKFGBFPE_01100	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKFGBFPE_01101	6.11e-111	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKFGBFPE_01102	1.2e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKFGBFPE_01103	7.66e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HKFGBFPE_01104	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKFGBFPE_01105	8.85e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKFGBFPE_01106	7.11e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKFGBFPE_01107	5.52e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKFGBFPE_01108	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKFGBFPE_01110	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_01111	2.91e-53	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HKFGBFPE_01112	2.27e-228	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HKFGBFPE_01113	1.73e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKFGBFPE_01114	5.28e-76	-	-	-	-	-	-	-	-
HKFGBFPE_01116	2.97e-249	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKFGBFPE_01117	4.37e-39	-	-	-	-	-	-	-	-
HKFGBFPE_01118	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HKFGBFPE_01119	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKFGBFPE_01120	1.16e-47	-	-	-	-	-	-	-	-
HKFGBFPE_01121	8.3e-134	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKFGBFPE_01122	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKFGBFPE_01123	2.31e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HKFGBFPE_01124	1.34e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKFGBFPE_01125	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKFGBFPE_01126	2.87e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKFGBFPE_01127	2.12e-178	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKFGBFPE_01128	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKFGBFPE_01129	2.75e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKFGBFPE_01130	1.83e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKFGBFPE_01131	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKFGBFPE_01132	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKFGBFPE_01133	2.58e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKFGBFPE_01134	7.55e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKFGBFPE_01135	1.41e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKFGBFPE_01136	3.18e-11	-	-	-	-	-	-	-	-
HKFGBFPE_01137	1.78e-83	-	-	-	-	-	-	-	-
HKFGBFPE_01138	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKFGBFPE_01139	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HKFGBFPE_01140	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKFGBFPE_01141	5.98e-211	-	-	-	GK	-	-	-	ROK family
HKFGBFPE_01142	6.87e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKFGBFPE_01143	1.76e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HKFGBFPE_01144	3.37e-307	-	-	-	E	-	-	-	amino acid
HKFGBFPE_01145	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKFGBFPE_01146	2.44e-36	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKFGBFPE_01147	2.53e-83	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKFGBFPE_01148	6.1e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKFGBFPE_01149	4.73e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKFGBFPE_01150	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKFGBFPE_01151	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKFGBFPE_01152	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01153	9.54e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFGBFPE_01154	2.79e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKFGBFPE_01155	3.61e-209	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HKFGBFPE_01156	2.64e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKFGBFPE_01157	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKFGBFPE_01158	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HKFGBFPE_01159	1.6e-77	-	-	-	-	-	-	-	-
HKFGBFPE_01161	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKFGBFPE_01162	4.61e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKFGBFPE_01163	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKFGBFPE_01164	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKFGBFPE_01165	5.44e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKFGBFPE_01166	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKFGBFPE_01167	2.16e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKFGBFPE_01168	6.38e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKFGBFPE_01169	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKFGBFPE_01170	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKFGBFPE_01171	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKFGBFPE_01172	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKFGBFPE_01173	8.73e-189	ylmH	-	-	S	-	-	-	S4 domain protein
HKFGBFPE_01174	4.08e-106	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKFGBFPE_01175	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKFGBFPE_01176	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKFGBFPE_01177	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKFGBFPE_01178	1.54e-33	-	-	-	-	-	-	-	-
HKFGBFPE_01179	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKFGBFPE_01180	9.43e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKFGBFPE_01181	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKFGBFPE_01182	4.35e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKFGBFPE_01183	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HKFGBFPE_01184	1.1e-156	-	-	-	S	-	-	-	repeat protein
HKFGBFPE_01185	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKFGBFPE_01186	1.04e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKFGBFPE_01187	1.53e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKFGBFPE_01188	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKFGBFPE_01189	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKFGBFPE_01190	1.2e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKFGBFPE_01191	4.19e-286	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKFGBFPE_01192	5.62e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKFGBFPE_01193	1.62e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKFGBFPE_01194	1.84e-282	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKFGBFPE_01195	1.56e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKFGBFPE_01196	5.53e-05	cdaR_3	-	-	QT	ko:K02647	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
HKFGBFPE_01199	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKFGBFPE_01200	2.34e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKFGBFPE_01203	5.92e-150	-	-	-	-	-	-	-	-
HKFGBFPE_01204	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_01205	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HKFGBFPE_01206	5.9e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKFGBFPE_01207	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKFGBFPE_01208	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKFGBFPE_01209	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKFGBFPE_01210	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKFGBFPE_01211	2e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKFGBFPE_01213	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKFGBFPE_01214	5.72e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HKFGBFPE_01215	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HKFGBFPE_01216	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKFGBFPE_01217	1.27e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKFGBFPE_01218	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKFGBFPE_01219	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_01220	1.75e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01221	3.01e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKFGBFPE_01222	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKFGBFPE_01223	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKFGBFPE_01224	1.65e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HKFGBFPE_01225	1.02e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKFGBFPE_01226	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKFGBFPE_01227	2.09e-265	yacL	-	-	S	-	-	-	domain protein
HKFGBFPE_01228	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKFGBFPE_01229	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKFGBFPE_01230	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKFGBFPE_01231	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKFGBFPE_01232	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKFGBFPE_01233	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKFGBFPE_01234	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKFGBFPE_01235	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKFGBFPE_01236	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HKFGBFPE_01238	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKFGBFPE_01239	3.1e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKFGBFPE_01240	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKFGBFPE_01241	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKFGBFPE_01242	2.39e-64	-	-	-	-	-	-	-	-
HKFGBFPE_01244	1.9e-61	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKFGBFPE_01245	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HKFGBFPE_01246	1.09e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKFGBFPE_01247	6.81e-172	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKFGBFPE_01248	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKFGBFPE_01249	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKFGBFPE_01250	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKFGBFPE_01251	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKFGBFPE_01252	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKFGBFPE_01253	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKFGBFPE_01254	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKFGBFPE_01255	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKFGBFPE_01256	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKFGBFPE_01257	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKFGBFPE_01258	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKFGBFPE_01259	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKFGBFPE_01260	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKFGBFPE_01261	5.48e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKFGBFPE_01262	1.82e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKFGBFPE_01263	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKFGBFPE_01264	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKFGBFPE_01265	5.83e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKFGBFPE_01266	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKFGBFPE_01267	1.19e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HKFGBFPE_01268	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HKFGBFPE_01269	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKFGBFPE_01270	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKFGBFPE_01271	7.63e-217	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKFGBFPE_01272	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKFGBFPE_01273	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKFGBFPE_01274	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKFGBFPE_01275	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKFGBFPE_01276	1.46e-08	-	-	-	S	-	-	-	CsbD-like
HKFGBFPE_01277	1.9e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HKFGBFPE_01278	9.15e-301	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKFGBFPE_01279	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HKFGBFPE_01280	1.56e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKFGBFPE_01281	2.86e-74	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HKFGBFPE_01283	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HKFGBFPE_01284	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKFGBFPE_01286	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKFGBFPE_01287	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKFGBFPE_01288	0.0	yycH	-	-	S	-	-	-	YycH protein
HKFGBFPE_01289	6.38e-196	yycI	-	-	S	-	-	-	YycH protein
HKFGBFPE_01290	3.06e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKFGBFPE_01291	6.24e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKFGBFPE_01292	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HKFGBFPE_01293	1.02e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKFGBFPE_01294	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKFGBFPE_01296	1.56e-125	-	-	-	S	-	-	-	reductase
HKFGBFPE_01297	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HKFGBFPE_01298	1.39e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKFGBFPE_01299	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
HKFGBFPE_01300	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKFGBFPE_01301	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKFGBFPE_01302	1.06e-202	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKFGBFPE_01303	1.69e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKFGBFPE_01304	3.16e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKFGBFPE_01306	7.63e-64	-	-	-	-	-	-	-	-
HKFGBFPE_01307	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKFGBFPE_01310	1.37e-35	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKFGBFPE_01311	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HKFGBFPE_01312	5.24e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFGBFPE_01313	2.83e-282	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKFGBFPE_01314	8.68e-44	-	-	-	-	-	-	-	-
HKFGBFPE_01315	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HKFGBFPE_01317	1.22e-139	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HKFGBFPE_01318	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKFGBFPE_01319	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKFGBFPE_01320	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKFGBFPE_01321	9.34e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKFGBFPE_01322	4.84e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKFGBFPE_01323	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKFGBFPE_01324	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKFGBFPE_01325	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKFGBFPE_01326	2.46e-93	-	-	-	-	-	-	-	-
HKFGBFPE_01327	1.68e-110	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HKFGBFPE_01328	1.1e-153	dltr	-	-	K	-	-	-	response regulator
HKFGBFPE_01329	5.59e-290	sptS	-	-	T	-	-	-	Histidine kinase
HKFGBFPE_01330	1.2e-268	-	-	-	P	-	-	-	Voltage gated chloride channel
HKFGBFPE_01331	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKFGBFPE_01332	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKFGBFPE_01333	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKFGBFPE_01334	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKFGBFPE_01335	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKFGBFPE_01336	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKFGBFPE_01337	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKFGBFPE_01338	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKFGBFPE_01339	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKFGBFPE_01340	5.64e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKFGBFPE_01341	4.22e-169	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKFGBFPE_01342	4.24e-249	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKFGBFPE_01343	9.45e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
HKFGBFPE_01344	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKFGBFPE_01345	4.15e-192	-	-	-	S	-	-	-	DUF218 domain
HKFGBFPE_01346	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKFGBFPE_01347	7.82e-80	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFGBFPE_01348	1.27e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFGBFPE_01349	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HKFGBFPE_01350	2.9e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKFGBFPE_01351	6.88e-296	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKFGBFPE_01352	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKFGBFPE_01355	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKFGBFPE_01356	1.78e-204	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKFGBFPE_01357	9.13e-232	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFGBFPE_01358	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HKFGBFPE_01359	1.76e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HKFGBFPE_01360	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HKFGBFPE_01361	8.05e-194	-	-	-	-	-	-	-	-
HKFGBFPE_01362	8.66e-37	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HKFGBFPE_01363	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKFGBFPE_01364	9.27e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKFGBFPE_01365	1.46e-96	-	-	-	F	-	-	-	Nudix hydrolase
HKFGBFPE_01366	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKFGBFPE_01367	4.84e-293	-	-	-	-	-	-	-	-
HKFGBFPE_01368	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_01369	7.65e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01370	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01371	7.22e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKFGBFPE_01372	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKFGBFPE_01373	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKFGBFPE_01374	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
HKFGBFPE_01375	6.45e-155	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKFGBFPE_01376	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HKFGBFPE_01377	1.7e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKFGBFPE_01378	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKFGBFPE_01379	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
HKFGBFPE_01380	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HKFGBFPE_01381	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HKFGBFPE_01382	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HKFGBFPE_01383	6.23e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HKFGBFPE_01384	1.19e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKFGBFPE_01385	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKFGBFPE_01386	4.39e-244	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HKFGBFPE_01387	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKFGBFPE_01388	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKFGBFPE_01389	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HKFGBFPE_01390	9.13e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HKFGBFPE_01391	1.77e-56	-	-	-	-	-	-	-	-
HKFGBFPE_01392	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKFGBFPE_01393	5.74e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HKFGBFPE_01394	1.48e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
HKFGBFPE_01395	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKFGBFPE_01396	5.74e-62	-	-	-	-	-	-	-	-
HKFGBFPE_01398	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKFGBFPE_01399	2.76e-277	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKFGBFPE_01400	1.43e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKFGBFPE_01401	3.53e-297	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
HKFGBFPE_01402	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HKFGBFPE_01403	1.41e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HKFGBFPE_01404	1.51e-199	-	-	-	J	-	-	-	Methyltransferase
HKFGBFPE_01405	1.73e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HKFGBFPE_01406	1.74e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKFGBFPE_01407	7.81e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HKFGBFPE_01409	0.0	-	-	-	-	-	-	-	-
HKFGBFPE_01410	7.75e-164	-	-	-	-	-	-	-	-
HKFGBFPE_01411	3.65e-100	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKFGBFPE_01419	1.12e-49	-	-	-	IQ	-	-	-	dehydrogenase reductase
HKFGBFPE_01420	2.64e-244	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKFGBFPE_01421	1e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKFGBFPE_01422	0.0	-	-	-	L	-	-	-	PLD-like domain
HKFGBFPE_01423	3.62e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
HKFGBFPE_01424	4.63e-174	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKFGBFPE_01425	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HKFGBFPE_01426	6.9e-134	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKFGBFPE_01427	1.37e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKFGBFPE_01428	2.26e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKFGBFPE_01429	2.47e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKFGBFPE_01430	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HKFGBFPE_01431	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKFGBFPE_01432	1.99e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HKFGBFPE_01433	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKFGBFPE_01434	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKFGBFPE_01435	5.17e-70	-	-	-	-	-	-	-	-
HKFGBFPE_01436	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HKFGBFPE_01437	7.53e-104	-	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_01438	4.88e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HKFGBFPE_01439	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HKFGBFPE_01441	2.06e-176	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKFGBFPE_01442	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKFGBFPE_01443	7.78e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKFGBFPE_01444	2.09e-154	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKFGBFPE_01445	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKFGBFPE_01446	2.69e-36	-	-	-	-	-	-	-	-
HKFGBFPE_01448	6.11e-44	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HKFGBFPE_01449	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKFGBFPE_01450	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKFGBFPE_01451	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKFGBFPE_01452	1.95e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKFGBFPE_01453	1.71e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKFGBFPE_01454	2.8e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HKFGBFPE_01455	9.42e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_01456	4.06e-184	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKFGBFPE_01457	2.33e-238	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HKFGBFPE_01458	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFGBFPE_01459	2e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFGBFPE_01460	9.18e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKFGBFPE_01461	3.3e-144	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HKFGBFPE_01462	4.15e-170	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKFGBFPE_01463	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HKFGBFPE_01464	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
HKFGBFPE_01465	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
HKFGBFPE_01466	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
HKFGBFPE_01467	3.59e-128	-	-	-	S	-	-	-	AmiS/UreI family transporter
HKFGBFPE_01468	1.31e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKFGBFPE_01469	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKFGBFPE_01470	4.48e-55	-	-	-	-	-	-	-	-
HKFGBFPE_01471	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKFGBFPE_01472	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKFGBFPE_01473	1.07e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HKFGBFPE_01474	2.59e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HKFGBFPE_01475	1.15e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKFGBFPE_01476	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
HKFGBFPE_01477	4.66e-197	-	-	-	V	-	-	-	(ABC) transporter
HKFGBFPE_01478	1.9e-115	-	-	-	GM	-	-	-	epimerase
HKFGBFPE_01479	1.51e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKFGBFPE_01480	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_01481	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HKFGBFPE_01482	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HKFGBFPE_01483	2.62e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01484	1.27e-151	-	-	-	-	-	-	-	-
HKFGBFPE_01485	1.57e-181	-	-	-	G	-	-	-	MucBP domain
HKFGBFPE_01486	6.36e-130	-	-	-	S	-	-	-	Pfam:DUF3816
HKFGBFPE_01487	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKFGBFPE_01488	9.69e-38	-	-	-	-	-	-	-	-
HKFGBFPE_01489	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKFGBFPE_01490	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKFGBFPE_01491	1.88e-292	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKFGBFPE_01492	4.82e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKFGBFPE_01493	1.8e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKFGBFPE_01494	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HKFGBFPE_01495	5.81e-295	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HKFGBFPE_01496	1.07e-52	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
HKFGBFPE_01497	1.72e-212	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HKFGBFPE_01498	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HKFGBFPE_01499	2.34e-266	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HKFGBFPE_01500	3.53e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
HKFGBFPE_01501	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKFGBFPE_01502	1.39e-169	-	-	-	F	-	-	-	NUDIX domain
HKFGBFPE_01504	1.04e-115	-	-	-	-	-	-	-	-
HKFGBFPE_01506	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKFGBFPE_01507	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKFGBFPE_01508	1.06e-228	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKFGBFPE_01509	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKFGBFPE_01510	2.67e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKFGBFPE_01511	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKFGBFPE_01512	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKFGBFPE_01513	2.39e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKFGBFPE_01514	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKFGBFPE_01515	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKFGBFPE_01516	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKFGBFPE_01517	0.0	-	-	-	S	-	-	-	membrane
HKFGBFPE_01518	4.64e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKFGBFPE_01519	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKFGBFPE_01520	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKFGBFPE_01521	3.57e-150	-	-	-	M	-	-	-	PFAM NLP P60 protein
HKFGBFPE_01522	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKFGBFPE_01523	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKFGBFPE_01524	4.77e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKFGBFPE_01525	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFGBFPE_01526	9.44e-187	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKFGBFPE_01527	1.07e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKFGBFPE_01528	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKFGBFPE_01529	5.74e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKFGBFPE_01530	1.84e-298	-	-	-	V	-	-	-	MatE
HKFGBFPE_01531	0.0	potE	-	-	E	-	-	-	Amino Acid
HKFGBFPE_01532	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKFGBFPE_01533	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HKFGBFPE_01534	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKFGBFPE_01535	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKFGBFPE_01536	1.75e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKFGBFPE_01537	9.84e-183	yqeM	-	-	Q	-	-	-	Methyltransferase
HKFGBFPE_01538	2.3e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKFGBFPE_01539	6.21e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKFGBFPE_01540	4.36e-161	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKFGBFPE_01541	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKFGBFPE_01542	1.9e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKFGBFPE_01543	1.91e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKFGBFPE_01544	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKFGBFPE_01545	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKFGBFPE_01546	2.15e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKFGBFPE_01547	7.37e-223	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKFGBFPE_01548	2.83e-299	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HKFGBFPE_01549	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKFGBFPE_01550	5.5e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKFGBFPE_01551	3.89e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKFGBFPE_01552	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKFGBFPE_01553	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKFGBFPE_01554	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKFGBFPE_01555	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKFGBFPE_01556	3.43e-154	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKFGBFPE_01557	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HKFGBFPE_01558	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
HKFGBFPE_01559	6.25e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HKFGBFPE_01560	5.08e-237	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HKFGBFPE_01561	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKFGBFPE_01562	0.0	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
HKFGBFPE_01563	3.3e-174	-	-	-	S	-	-	-	YSIRK type signal peptide
HKFGBFPE_01564	2.82e-34	-	-	-	S	-	-	-	YSIRK type signal peptide
HKFGBFPE_01565	9.15e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKFGBFPE_01566	3.44e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKFGBFPE_01567	1.39e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01568	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HKFGBFPE_01570	1e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKFGBFPE_01571	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKFGBFPE_01572	3.37e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKFGBFPE_01573	3.9e-79	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKFGBFPE_01574	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKFGBFPE_01575	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKFGBFPE_01576	1.51e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKFGBFPE_01577	4.93e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKFGBFPE_01579	1.49e-54	-	-	-	-	-	-	-	-
HKFGBFPE_01580	5.38e-60	-	-	-	-	-	-	-	-
HKFGBFPE_01582	1.05e-305	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKFGBFPE_01583	1.28e-75	-	-	-	-	-	-	-	-
HKFGBFPE_01585	2.8e-116	-	-	-	-	-	-	-	-
HKFGBFPE_01586	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKFGBFPE_01587	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HKFGBFPE_01588	1.53e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
HKFGBFPE_01589	1.04e-135	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HKFGBFPE_01590	1.92e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HKFGBFPE_01591	6.53e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HKFGBFPE_01592	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKFGBFPE_01593	2.24e-200	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HKFGBFPE_01594	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKFGBFPE_01595	3.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKFGBFPE_01596	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKFGBFPE_01597	2.07e-236	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKFGBFPE_01598	7.36e-110	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HKFGBFPE_01599	0.0	-	-	-	M	-	-	-	domain protein
HKFGBFPE_01600	2.51e-83	-	-	-	-	-	-	-	-
HKFGBFPE_01601	3e-251	ampC	-	-	V	-	-	-	Beta-lactamase
HKFGBFPE_01602	7.24e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HKFGBFPE_01603	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKFGBFPE_01604	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HKFGBFPE_01605	6.17e-301	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HKFGBFPE_01606	3.89e-67	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKFGBFPE_01607	5.53e-24	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKFGBFPE_01608	1.06e-48	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKFGBFPE_01609	9.78e-148	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKFGBFPE_01610	1.76e-162	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKFGBFPE_01611	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKFGBFPE_01612	3.49e-192	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKFGBFPE_01613	1.56e-59	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HKFGBFPE_01614	8.13e-153	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HKFGBFPE_01616	7.84e-126	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKFGBFPE_01617	4.46e-199	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKFGBFPE_01618	1.81e-43	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKFGBFPE_01622	2.78e-111	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HKFGBFPE_01624	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_01625	3.99e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01626	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKFGBFPE_01628	3.34e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKFGBFPE_01629	6.51e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKFGBFPE_01630	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKFGBFPE_01631	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKFGBFPE_01632	8.46e-77	-	-	-	-	-	-	-	-
HKFGBFPE_01633	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKFGBFPE_01634	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKFGBFPE_01635	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01636	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01637	9.45e-196	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKFGBFPE_01638	4.64e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01639	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKFGBFPE_01640	4.71e-142	-	-	-	S	-	-	-	VIT family
HKFGBFPE_01641	3.63e-152	-	-	-	S	-	-	-	membrane
HKFGBFPE_01642	4.04e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKFGBFPE_01643	2.32e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKFGBFPE_01644	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKFGBFPE_01645	7.95e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKFGBFPE_01646	2.59e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKFGBFPE_01647	2.79e-153	-	-	-	I	-	-	-	phosphatase
HKFGBFPE_01648	8.71e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKFGBFPE_01649	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HKFGBFPE_01650	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKFGBFPE_01656	4.02e-53	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKFGBFPE_01657	2.57e-23	-	-	-	S	-	-	-	sequence-specific DNA binding
HKFGBFPE_01658	2.41e-20	-	-	-	-	-	-	-	-
HKFGBFPE_01659	5.75e-37	-	-	-	-	-	-	-	-
HKFGBFPE_01661	1.24e-56	-	-	-	S	-	-	-	calcium ion binding
HKFGBFPE_01664	3.68e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKFGBFPE_01665	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HKFGBFPE_01666	8.39e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HKFGBFPE_01667	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKFGBFPE_01668	1.28e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKFGBFPE_01669	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKFGBFPE_01670	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKFGBFPE_01671	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKFGBFPE_01672	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKFGBFPE_01673	4.52e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKFGBFPE_01674	9.97e-245	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKFGBFPE_01675	1.11e-260	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKFGBFPE_01676	1.86e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKFGBFPE_01677	2.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKFGBFPE_01678	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKFGBFPE_01679	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKFGBFPE_01680	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKFGBFPE_01681	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKFGBFPE_01682	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKFGBFPE_01683	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
HKFGBFPE_01684	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKFGBFPE_01685	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKFGBFPE_01686	3.01e-126	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKFGBFPE_01687	3.41e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKFGBFPE_01688	5.35e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKFGBFPE_01689	1.16e-124	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKFGBFPE_01690	1.79e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HKFGBFPE_01691	1.4e-198	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKFGBFPE_01692	1.6e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKFGBFPE_01693	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKFGBFPE_01694	2.93e-58	-	-	-	-	-	-	-	-
HKFGBFPE_01695	6.25e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKFGBFPE_01696	1.7e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKFGBFPE_01697	5.96e-181	-	-	-	-	-	-	-	-
HKFGBFPE_01698	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKFGBFPE_01699	8.77e-237	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKFGBFPE_01700	2.95e-240	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKFGBFPE_01701	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HKFGBFPE_01702	3.65e-103	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HKFGBFPE_01703	3.65e-60	-	-	-	-	-	-	-	-
HKFGBFPE_01704	1.01e-95	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HKFGBFPE_01706	5.09e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKFGBFPE_01707	1.36e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKFGBFPE_01708	6.01e-153	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKFGBFPE_01709	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKFGBFPE_01710	1.44e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKFGBFPE_01711	7.15e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKFGBFPE_01712	1.29e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKFGBFPE_01713	3.51e-103	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKFGBFPE_01714	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKFGBFPE_01715	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKFGBFPE_01716	2.59e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKFGBFPE_01717	4.1e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKFGBFPE_01718	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKFGBFPE_01719	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKFGBFPE_01720	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKFGBFPE_01721	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKFGBFPE_01722	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKFGBFPE_01723	1.09e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKFGBFPE_01724	1.9e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKFGBFPE_01725	5.97e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKFGBFPE_01726	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKFGBFPE_01727	7.72e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKFGBFPE_01728	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HKFGBFPE_01729	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKFGBFPE_01730	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKFGBFPE_01731	2.84e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKFGBFPE_01732	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKFGBFPE_01733	1.52e-263	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKFGBFPE_01734	4.93e-24	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKFGBFPE_01735	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKFGBFPE_01736	0.0	snf	-	-	KL	-	-	-	domain protein
HKFGBFPE_01738	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HKFGBFPE_01739	1.25e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HKFGBFPE_01740	1.91e-142	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKFGBFPE_01741	2.4e-315	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKFGBFPE_01742	5.14e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKFGBFPE_01744	7.28e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HKFGBFPE_01745	1.62e-29	-	-	-	S	-	-	-	Region found in RelA / SpoT proteins
HKFGBFPE_01746	2.63e-53	-	-	-	-	-	-	-	-
HKFGBFPE_01747	0.0	ydaO	-	-	E	-	-	-	amino acid
HKFGBFPE_01748	0.0	-	-	-	E	-	-	-	amino acid
HKFGBFPE_01749	3.5e-112	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HKFGBFPE_01750	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKFGBFPE_01751	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKFGBFPE_01753	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKFGBFPE_01754	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKFGBFPE_01755	2.61e-236	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKFGBFPE_01756	1.37e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKFGBFPE_01757	3.05e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKFGBFPE_01758	2.29e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKFGBFPE_01759	3.8e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKFGBFPE_01760	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKFGBFPE_01761	1.74e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKFGBFPE_01762	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKFGBFPE_01763	1.18e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKFGBFPE_01764	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKFGBFPE_01765	4.39e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKFGBFPE_01766	8.12e-46	-	-	-	LM	-	-	-	gp58-like protein
HKFGBFPE_01773	7.69e-45	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HKFGBFPE_01774	1.03e-185	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKFGBFPE_01776	1.48e-72	lysR	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_01777	1.64e-105	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKFGBFPE_01778	8.13e-182	-	-	-	S	-	-	-	Alpha beta hydrolase
HKFGBFPE_01779	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKFGBFPE_01780	3.79e-222	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKFGBFPE_01781	6.78e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HKFGBFPE_01782	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKFGBFPE_01783	2.82e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HKFGBFPE_01784	2.62e-184	-	-	-	K	-	-	-	Transcriptional regulator
HKFGBFPE_01785	9.48e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKFGBFPE_01786	1.28e-125	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HKFGBFPE_01787	8.96e-79	-	-	-	-	-	-	-	-
HKFGBFPE_01788	8.44e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HKFGBFPE_01789	9.34e-59	-	-	-	T	-	-	-	EAL domain
HKFGBFPE_01790	8.79e-107	-	-	-	T	-	-	-	EAL domain
HKFGBFPE_01791	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKFGBFPE_01792	3.34e-107	-	-	-	-	-	-	-	-
HKFGBFPE_01793	1.64e-252	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HKFGBFPE_01794	3.83e-153	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKFGBFPE_01795	8.54e-34	-	-	-	-	-	-	-	-
HKFGBFPE_01796	1.53e-127	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKFGBFPE_01797	3.82e-47	-	-	-	-	-	-	-	-
HKFGBFPE_01798	2.26e-115	-	-	-	-	-	-	-	-
HKFGBFPE_01799	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKFGBFPE_01800	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKFGBFPE_01801	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKFGBFPE_01802	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKFGBFPE_01803	2.29e-130	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKFGBFPE_01804	4.87e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HKFGBFPE_01805	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKFGBFPE_01806	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKFGBFPE_01807	7.9e-214	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HKFGBFPE_01808	6.73e-149	-	-	-	M	-	-	-	LysM domain protein
HKFGBFPE_01809	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HKFGBFPE_01810	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
HKFGBFPE_01811	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKFGBFPE_01812	1.14e-312	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKFGBFPE_01813	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKFGBFPE_01814	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HKFGBFPE_01815	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKFGBFPE_01816	2.94e-110	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKFGBFPE_01817	2.24e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKFGBFPE_01818	1.81e-108	-	-	-	-	-	-	-	-
HKFGBFPE_01819	2.4e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKFGBFPE_01820	3e-274	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKFGBFPE_01821	6e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKFGBFPE_01823	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKFGBFPE_01824	4.49e-130	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKFGBFPE_01825	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKFGBFPE_01826	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKFGBFPE_01827	8.74e-57	-	-	-	-	-	-	-	-
HKFGBFPE_01828	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKFGBFPE_01829	9.07e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKFGBFPE_01830	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKFGBFPE_01831	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKFGBFPE_01832	7.5e-13	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKFGBFPE_01833	4.93e-216	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKFGBFPE_01834	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKFGBFPE_01835	5.33e-147	-	-	-	-	-	-	-	-
HKFGBFPE_01836	3.07e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKFGBFPE_01837	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKFGBFPE_01838	1.52e-43	-	-	-	-	-	-	-	-
HKFGBFPE_01839	2.21e-155	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKFGBFPE_01841	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKFGBFPE_01842	3.1e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKFGBFPE_01843	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKFGBFPE_01844	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKFGBFPE_01845	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKFGBFPE_01846	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKFGBFPE_01847	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKFGBFPE_01848	6.17e-192	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HKFGBFPE_01849	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKFGBFPE_01850	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKFGBFPE_01852	6.68e-238	-	-	-	-	-	-	-	-
HKFGBFPE_01853	9.45e-126	-	-	-	K	-	-	-	acetyltransferase
HKFGBFPE_01854	5.67e-178	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKFGBFPE_01855	1.93e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HKFGBFPE_01856	1.11e-263	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HKFGBFPE_01857	5.53e-52	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKFGBFPE_01858	2.96e-225	-	-	-	-	-	-	-	-
HKFGBFPE_01859	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKFGBFPE_01860	7.01e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKFGBFPE_01862	2.51e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKFGBFPE_01863	3.82e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKFGBFPE_01864	1.1e-161	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKFGBFPE_01865	2.26e-149	-	-	-	S	-	-	-	Membrane
HKFGBFPE_01866	3.39e-254	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKFGBFPE_01867	1.26e-113	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKFGBFPE_01868	3.7e-19	-	-	-	-	-	-	-	-
HKFGBFPE_01869	3.69e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKFGBFPE_01870	7.98e-114	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKFGBFPE_01871	2.42e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HKFGBFPE_01872	5.69e-105	-	-	-	-	-	-	-	-
HKFGBFPE_01873	6.75e-164	-	-	-	M	-	-	-	Lysin motif
HKFGBFPE_01874	3.92e-163	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_01875	4.63e-70	-	-	-	EGP	-	-	-	Major Facilitator
HKFGBFPE_01876	1.21e-48	-	-	-	-	-	-	-	-
HKFGBFPE_01877	1.65e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKFGBFPE_01878	4.87e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKFGBFPE_01879	7.24e-239	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKFGBFPE_01880	1.08e-289	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKFGBFPE_01881	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKFGBFPE_01882	2.92e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKFGBFPE_01883	1.09e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HKFGBFPE_01884	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKFGBFPE_01885	3.83e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HKFGBFPE_01886	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HKFGBFPE_01887	5.13e-46	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKFGBFPE_01888	1.36e-99	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKFGBFPE_01889	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKFGBFPE_01890	5.11e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKFGBFPE_01891	7.18e-126	-	-	-	-	-	-	-	-
HKFGBFPE_01892	7.48e-155	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFGBFPE_01893	9.18e-206	gspA	-	-	M	-	-	-	family 8
HKFGBFPE_01894	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HKFGBFPE_01895	1.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKFGBFPE_01896	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKFGBFPE_01897	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKFGBFPE_01898	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKFGBFPE_01899	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKFGBFPE_01900	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HKFGBFPE_01901	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKFGBFPE_01902	1.2e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKFGBFPE_01903	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKFGBFPE_01904	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKFGBFPE_01905	1.36e-136	-	-	-	-	-	-	-	-
HKFGBFPE_01906	2.84e-27	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HKFGBFPE_01907	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKFGBFPE_01908	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKFGBFPE_01909	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKFGBFPE_01910	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKFGBFPE_01911	1.91e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKFGBFPE_01912	1.45e-152	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HKFGBFPE_01913	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKFGBFPE_01914	3.01e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKFGBFPE_01915	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKFGBFPE_01916	8.23e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKFGBFPE_01917	2.02e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFGBFPE_01918	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKFGBFPE_01919	6.72e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKFGBFPE_01920	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKFGBFPE_01921	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKFGBFPE_01922	6.79e-91	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKFGBFPE_01923	3.43e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HKFGBFPE_01924	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HKFGBFPE_01925	1.14e-190	yidA	-	-	S	-	-	-	hydrolase