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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HPMAHIPH_00003	1.23e-124	-	-	-	S	-	-	-	Prophage endopeptidase tail
HPMAHIPH_00005	2.12e-181	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HPMAHIPH_00008	1.31e-58	-	-	-	N	-	-	-	domain, Protein
HPMAHIPH_00012	2.68e-20	-	-	-	-	-	-	-	-
HPMAHIPH_00014	4.94e-135	-	-	-	-	-	-	-	-
HPMAHIPH_00017	4.82e-54	-	-	-	S	-	-	-	Phage minor capsid protein 2
HPMAHIPH_00018	1.89e-137	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPMAHIPH_00019	6.16e-227	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
HPMAHIPH_00020	1.45e-49	-	-	-	-	-	-	-	-
HPMAHIPH_00022	6.63e-34	-	-	-	-	-	-	-	-
HPMAHIPH_00023	1.48e-29	-	-	-	-	-	-	-	-
HPMAHIPH_00024	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
HPMAHIPH_00025	7.55e-35	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HPMAHIPH_00026	3.75e-07	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HPMAHIPH_00027	2.85e-103	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HPMAHIPH_00028	1.37e-174	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HPMAHIPH_00029	4.02e-179	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HPMAHIPH_00030	5.14e-41	-	-	-	-	-	-	-	-
HPMAHIPH_00031	6.11e-53	-	-	-	K	-	-	-	Transcriptional regulator (AraC family)
HPMAHIPH_00032	2.24e-159	-	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	Sugar (and other) transporter
HPMAHIPH_00033	6.51e-139	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HPMAHIPH_00034	1.39e-20	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HPMAHIPH_00035	1.52e-12	-	-	-	K	-	-	-	Sensory domain found in PocR
HPMAHIPH_00036	9.47e-105	icaA	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
HPMAHIPH_00038	1.08e-81	icaB	-	-	G	ko:K21478	-	ko00000,ko01000	deacetylase
HPMAHIPH_00039	7.26e-67	-	-	-	-	-	-	-	-
HPMAHIPH_00040	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPMAHIPH_00041	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPMAHIPH_00042	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPMAHIPH_00043	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPMAHIPH_00044	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPMAHIPH_00045	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HPMAHIPH_00046	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HPMAHIPH_00047	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HPMAHIPH_00048	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HPMAHIPH_00049	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_00050	8.57e-41	-	-	-	-	-	-	-	-
HPMAHIPH_00051	7.74e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HPMAHIPH_00052	1.33e-77	-	-	-	-	-	-	-	-
HPMAHIPH_00053	5.37e-182	-	-	-	-	-	-	-	-
HPMAHIPH_00054	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HPMAHIPH_00055	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00056	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HPMAHIPH_00057	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HPMAHIPH_00059	1.03e-57	-	-	-	S	-	-	-	Bacteriophage holin
HPMAHIPH_00060	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HPMAHIPH_00061	4.95e-118	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HPMAHIPH_00062	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HPMAHIPH_00063	3.73e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPMAHIPH_00064	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPMAHIPH_00065	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HPMAHIPH_00066	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HPMAHIPH_00067	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HPMAHIPH_00068	2.82e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_00069	1.68e-299	-	-	-	M	-	-	-	Collagen binding domain
HPMAHIPH_00070	0.0	-	-	-	I	-	-	-	acetylesterase activity
HPMAHIPH_00071	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HPMAHIPH_00072	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HPMAHIPH_00073	4.29e-50	-	-	-	-	-	-	-	-
HPMAHIPH_00075	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
HPMAHIPH_00076	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HPMAHIPH_00077	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPMAHIPH_00078	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPMAHIPH_00079	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HPMAHIPH_00080	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HPMAHIPH_00081	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HPMAHIPH_00082	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPMAHIPH_00083	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HPMAHIPH_00084	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_00085	1.14e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HPMAHIPH_00086	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HPMAHIPH_00087	4.31e-39	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HPMAHIPH_00088	5.48e-05	-	-	-	S	-	-	-	Short C-terminal domain
HPMAHIPH_00089	1.66e-22	-	-	-	S	-	-	-	Short C-terminal domain
HPMAHIPH_00090	1.28e-06	-	-	-	-	-	-	-	-
HPMAHIPH_00093	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HPMAHIPH_00094	1.75e-51	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_00095	9.04e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_00097	5.68e-106	-	-	-	-	-	-	-	-
HPMAHIPH_00098	1.35e-34	-	-	-	L	-	-	-	HTH-like domain
HPMAHIPH_00099	1.32e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_00100	2.73e-46	-	-	-	K	-	-	-	Helix-turn-helix
HPMAHIPH_00104	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HPMAHIPH_00105	2.62e-08	-	-	-	K	-	-	-	Transcriptional regulator, XRE family
HPMAHIPH_00108	7.71e-71	-	-	-	-	-	-	-	-
HPMAHIPH_00109	1.56e-103	-	-	-	-	-	-	-	-
HPMAHIPH_00114	8.76e-74	-	-	-	S	-	-	-	YopX protein
HPMAHIPH_00116	1.61e-11	-	-	-	-	-	-	-	-
HPMAHIPH_00117	2.82e-06	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
HPMAHIPH_00122	8.28e-87	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HPMAHIPH_00123	1.63e-105	-	-	-	-	-	-	-	-
HPMAHIPH_00128	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HPMAHIPH_00129	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HPMAHIPH_00130	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HPMAHIPH_00131	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HPMAHIPH_00132	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMAHIPH_00133	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_00134	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HPMAHIPH_00135	2.51e-288	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HPMAHIPH_00136	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_00137	1.56e-98	-	-	-	-	-	-	-	-
HPMAHIPH_00138	1.11e-240	-	-	-	S	-	-	-	Cell surface protein
HPMAHIPH_00139	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_00140	9.33e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HPMAHIPH_00141	1.22e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HPMAHIPH_00142	3.33e-149	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HPMAHIPH_00143	1.59e-243	ynjC	-	-	S	-	-	-	Cell surface protein
HPMAHIPH_00144	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_00145	1.47e-83	-	-	-	-	-	-	-	-
HPMAHIPH_00146	1.65e-306	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HPMAHIPH_00147	4.13e-157	-	-	-	-	-	-	-	-
HPMAHIPH_00148	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPMAHIPH_00149	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HPMAHIPH_00150	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_00151	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HPMAHIPH_00152	4.61e-103	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HPMAHIPH_00153	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HPMAHIPH_00154	3.26e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HPMAHIPH_00155	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HPMAHIPH_00156	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00157	2.18e-215	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00158	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HPMAHIPH_00159	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPMAHIPH_00160	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HPMAHIPH_00161	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPMAHIPH_00162	3.27e-170	-	-	-	S	-	-	-	KR domain
HPMAHIPH_00163	6.76e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00164	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HPMAHIPH_00165	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HPMAHIPH_00166	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
HPMAHIPH_00167	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HPMAHIPH_00168	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00169	3.49e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HPMAHIPH_00170	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HPMAHIPH_00171	2.58e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPMAHIPH_00172	1.35e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPMAHIPH_00173	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00174	2.03e-201	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00175	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_00176	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HPMAHIPH_00177	4.31e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPMAHIPH_00178	4.51e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_00179	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HPMAHIPH_00180	3.51e-232	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HPMAHIPH_00181	1.87e-107	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_00182	8.05e-267	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HPMAHIPH_00183	1.97e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00184	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPMAHIPH_00185	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HPMAHIPH_00186	3.73e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HPMAHIPH_00187	4.71e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_00188	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPMAHIPH_00189	0.0	-	-	-	S	-	-	-	MucBP domain
HPMAHIPH_00191	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HPMAHIPH_00192	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HPMAHIPH_00193	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_00194	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_00195	4.9e-84	-	-	-	-	-	-	-	-
HPMAHIPH_00196	5.15e-16	-	-	-	-	-	-	-	-
HPMAHIPH_00197	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HPMAHIPH_00198	2.32e-29	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00199	2.08e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HPMAHIPH_00200	3.49e-272	-	-	-	S	-	-	-	Membrane
HPMAHIPH_00201	3.48e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HPMAHIPH_00202	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HPMAHIPH_00203	1.4e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPMAHIPH_00204	8.95e-53	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HPMAHIPH_00205	1.68e-121	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HPMAHIPH_00206	1.83e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HPMAHIPH_00207	6.27e-104	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPMAHIPH_00208	5.04e-92	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPMAHIPH_00209	5.68e-155	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HPMAHIPH_00210	2.31e-132	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HPMAHIPH_00211	4.71e-47	-	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HPMAHIPH_00212	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_00213	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
HPMAHIPH_00214	2.52e-304	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HPMAHIPH_00215	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HPMAHIPH_00216	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00217	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HPMAHIPH_00218	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HPMAHIPH_00219	9.3e-144	-	-	-	S	-	-	-	membrane
HPMAHIPH_00220	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HPMAHIPH_00221	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HPMAHIPH_00222	0.0	-	-	-	S	-	-	-	membrane
HPMAHIPH_00223	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HPMAHIPH_00224	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HPMAHIPH_00225	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPMAHIPH_00226	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HPMAHIPH_00227	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HPMAHIPH_00228	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HPMAHIPH_00229	5.43e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HPMAHIPH_00230	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HPMAHIPH_00231	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HPMAHIPH_00232	6.38e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HPMAHIPH_00233	9.34e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPMAHIPH_00234	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HPMAHIPH_00235	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HPMAHIPH_00236	1.77e-205	-	-	-	-	-	-	-	-
HPMAHIPH_00237	1.34e-232	-	-	-	-	-	-	-	-
HPMAHIPH_00238	7.16e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
HPMAHIPH_00239	3.11e-73	-	-	-	-	-	-	-	-
HPMAHIPH_00240	2.97e-41	-	-	-	-	-	-	-	-
HPMAHIPH_00241	3.77e-141	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_00244	2.44e-36	-	-	-	-	-	-	-	-
HPMAHIPH_00245	8.97e-47	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HPMAHIPH_00246	1.52e-34	-	-	-	CE	-	-	-	IrrE N-terminal-like domain
HPMAHIPH_00247	1.05e-16	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HPMAHIPH_00249	1.21e-145	-	-	-	K	-	-	-	ORF6N domain
HPMAHIPH_00250	8.39e-85	-	-	-	S	-	-	-	ORF6C domain
HPMAHIPH_00251	1.1e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HPMAHIPH_00253	6.14e-29	-	-	-	-	-	-	-	-
HPMAHIPH_00256	2.31e-98	-	-	-	L	-	-	-	DnaD domain protein
HPMAHIPH_00257	3.47e-210	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HPMAHIPH_00259	1.42e-45	-	-	-	-	-	-	-	-
HPMAHIPH_00260	2.2e-24	-	-	-	-	-	-	-	-
HPMAHIPH_00262	2.44e-22	-	-	-	S	-	-	-	YopX protein
HPMAHIPH_00265	2.28e-25	-	-	-	-	-	-	-	-
HPMAHIPH_00266	9.31e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HPMAHIPH_00268	3.39e-15	-	-	-	V	-	-	-	HNH nucleases
HPMAHIPH_00270	2.43e-116	-	-	-	L	-	-	-	HNH nucleases
HPMAHIPH_00271	4.02e-104	-	-	-	S	-	-	-	Phage terminase, small subunit
HPMAHIPH_00272	0.0	-	-	-	S	-	-	-	Phage Terminase
HPMAHIPH_00273	1.64e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HPMAHIPH_00274	8.48e-285	-	-	-	S	-	-	-	Phage portal protein
HPMAHIPH_00275	1.82e-162	-	-	-	S	-	-	-	Clp protease
HPMAHIPH_00276	3.05e-280	-	-	-	S	-	-	-	Phage capsid family
HPMAHIPH_00277	5.21e-71	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HPMAHIPH_00278	1.64e-74	-	-	-	S	-	-	-	Phage head-tail joining protein
HPMAHIPH_00279	9.94e-90	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HPMAHIPH_00280	4.69e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HPMAHIPH_00281	3.85e-128	-	-	-	S	-	-	-	Phage tail tube protein
HPMAHIPH_00282	1.85e-73	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HPMAHIPH_00283	1.47e-26	-	-	-	-	-	-	-	-
HPMAHIPH_00284	0.0	-	-	-	D	-	-	-	domain protein
HPMAHIPH_00285	6.39e-283	-	-	-	S	-	-	-	Phage tail protein
HPMAHIPH_00286	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HPMAHIPH_00290	7.11e-71	-	-	-	-	-	-	-	-
HPMAHIPH_00291	4.95e-225	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPMAHIPH_00292	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HPMAHIPH_00296	9.81e-27	-	-	-	-	-	-	-	-
HPMAHIPH_00297	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00298	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HPMAHIPH_00299	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HPMAHIPH_00300	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HPMAHIPH_00301	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HPMAHIPH_00302	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPMAHIPH_00303	2.82e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HPMAHIPH_00304	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPMAHIPH_00305	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPMAHIPH_00306	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPMAHIPH_00307	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPMAHIPH_00308	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPMAHIPH_00309	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HPMAHIPH_00310	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HPMAHIPH_00311	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HPMAHIPH_00312	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00313	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_00314	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPMAHIPH_00315	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_00316	2.38e-72	-	-	-	-	-	-	-	-
HPMAHIPH_00317	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HPMAHIPH_00318	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPMAHIPH_00319	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPMAHIPH_00320	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPMAHIPH_00321	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPMAHIPH_00322	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPMAHIPH_00323	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HPMAHIPH_00324	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HPMAHIPH_00325	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPMAHIPH_00326	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HPMAHIPH_00327	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HPMAHIPH_00328	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HPMAHIPH_00329	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HPMAHIPH_00330	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HPMAHIPH_00331	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPMAHIPH_00332	2.96e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPMAHIPH_00333	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPMAHIPH_00334	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPMAHIPH_00335	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HPMAHIPH_00336	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPMAHIPH_00337	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPMAHIPH_00338	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPMAHIPH_00339	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HPMAHIPH_00340	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HPMAHIPH_00341	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPMAHIPH_00342	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HPMAHIPH_00343	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPMAHIPH_00344	1.03e-66	-	-	-	-	-	-	-	-
HPMAHIPH_00346	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HPMAHIPH_00347	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HPMAHIPH_00348	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPMAHIPH_00349	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPMAHIPH_00350	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HPMAHIPH_00351	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HPMAHIPH_00352	2.2e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HPMAHIPH_00353	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPMAHIPH_00354	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPMAHIPH_00355	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HPMAHIPH_00356	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HPMAHIPH_00357	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HPMAHIPH_00358	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HPMAHIPH_00359	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HPMAHIPH_00360	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HPMAHIPH_00361	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPMAHIPH_00362	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPMAHIPH_00363	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPMAHIPH_00364	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HPMAHIPH_00365	8.04e-144	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HPMAHIPH_00366	6.54e-169	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HPMAHIPH_00367	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HPMAHIPH_00368	7.67e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HPMAHIPH_00369	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HPMAHIPH_00370	0.0	ydaO	-	-	E	-	-	-	amino acid
HPMAHIPH_00371	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPMAHIPH_00372	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPMAHIPH_00373	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_00374	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPMAHIPH_00375	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HPMAHIPH_00376	8.22e-264	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HPMAHIPH_00377	6.71e-191	-	4.1.1.74	-	GH	ko:K04103	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_00379	1.66e-27	-	-	-	K	ko:K07729	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HPMAHIPH_00382	5.98e-31	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HPMAHIPH_00383	4.81e-253	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HPMAHIPH_00384	2.57e-199	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HPMAHIPH_00385	1.51e-150	-	-	-	M	-	-	-	domain protein
HPMAHIPH_00386	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HPMAHIPH_00389	7.02e-113	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HPMAHIPH_00390	4.04e-50	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Shikimate / quinate 5-dehydrogenase
HPMAHIPH_00391	1.14e-115	-	-	-	-	-	-	-	-
HPMAHIPH_00392	8.46e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMAHIPH_00393	2.8e-40	-	-	-	K	-	-	-	MarR family
HPMAHIPH_00396	5.85e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HPMAHIPH_00397	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HPMAHIPH_00398	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPMAHIPH_00399	5.89e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMAHIPH_00400	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HPMAHIPH_00401	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_00402	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_00403	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HPMAHIPH_00405	0.0	-	-	-	M	-	-	-	domain protein
HPMAHIPH_00406	1.72e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_00407	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HPMAHIPH_00408	8.92e-317	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HPMAHIPH_00409	2e-211	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HPMAHIPH_00410	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HPMAHIPH_00411	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HPMAHIPH_00412	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HPMAHIPH_00413	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_00414	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMAHIPH_00415	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HPMAHIPH_00416	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HPMAHIPH_00417	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HPMAHIPH_00418	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HPMAHIPH_00419	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPMAHIPH_00420	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HPMAHIPH_00421	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HPMAHIPH_00422	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_00423	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_00424	5.47e-298	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPMAHIPH_00425	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HPMAHIPH_00426	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HPMAHIPH_00427	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HPMAHIPH_00428	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_00429	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HPMAHIPH_00430	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HPMAHIPH_00431	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HPMAHIPH_00432	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HPMAHIPH_00433	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00435	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HPMAHIPH_00436	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HPMAHIPH_00437	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_00438	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HPMAHIPH_00439	4.24e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_00440	1.44e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMAHIPH_00441	3.37e-115	-	-	-	-	-	-	-	-
HPMAHIPH_00442	1.57e-191	-	-	-	-	-	-	-	-
HPMAHIPH_00443	3.52e-179	-	-	-	-	-	-	-	-
HPMAHIPH_00444	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HPMAHIPH_00445	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HPMAHIPH_00447	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HPMAHIPH_00448	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00449	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HPMAHIPH_00450	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HPMAHIPH_00451	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_00452	4.03e-132	-	-	-	-	-	-	-	-
HPMAHIPH_00453	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HPMAHIPH_00454	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HPMAHIPH_00455	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HPMAHIPH_00456	4.36e-204	morA	-	-	S	-	-	-	reductase
HPMAHIPH_00458	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HPMAHIPH_00459	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_00460	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HPMAHIPH_00461	6.2e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HPMAHIPH_00462	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HPMAHIPH_00463	4.45e-99	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00464	2.01e-141	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HPMAHIPH_00465	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HPMAHIPH_00466	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HPMAHIPH_00467	2.94e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HPMAHIPH_00468	4.26e-158	-	-	-	-	-	-	-	-
HPMAHIPH_00469	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HPMAHIPH_00470	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HPMAHIPH_00471	0.0	-	-	-	L	-	-	-	HIRAN domain
HPMAHIPH_00472	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HPMAHIPH_00473	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HPMAHIPH_00474	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPMAHIPH_00475	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HPMAHIPH_00476	3.77e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPMAHIPH_00478	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPMAHIPH_00479	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HPMAHIPH_00480	4.84e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_00481	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HPMAHIPH_00482	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPMAHIPH_00483	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HPMAHIPH_00484	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HPMAHIPH_00485	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HPMAHIPH_00486	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HPMAHIPH_00487	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HPMAHIPH_00488	7.11e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_00489	1.67e-54	-	-	-	-	-	-	-	-
HPMAHIPH_00490	7.9e-142	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HPMAHIPH_00491	4.07e-05	-	-	-	-	-	-	-	-
HPMAHIPH_00492	4.85e-180	-	-	-	-	-	-	-	-
HPMAHIPH_00493	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HPMAHIPH_00494	2.38e-99	-	-	-	-	-	-	-	-
HPMAHIPH_00495	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HPMAHIPH_00496	3.36e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HPMAHIPH_00497	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HPMAHIPH_00498	1.1e-112	-	-	-	-	-	-	-	-
HPMAHIPH_00499	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPMAHIPH_00500	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HPMAHIPH_00502	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HPMAHIPH_00503	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HPMAHIPH_00504	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPMAHIPH_00505	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HPMAHIPH_00506	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HPMAHIPH_00507	2.97e-286	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPMAHIPH_00508	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPMAHIPH_00509	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HPMAHIPH_00510	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HPMAHIPH_00511	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HPMAHIPH_00512	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HPMAHIPH_00513	1.38e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HPMAHIPH_00514	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HPMAHIPH_00515	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HPMAHIPH_00516	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_00517	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00518	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPMAHIPH_00519	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPMAHIPH_00520	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPMAHIPH_00521	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HPMAHIPH_00522	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HPMAHIPH_00523	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPMAHIPH_00524	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPMAHIPH_00525	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HPMAHIPH_00526	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HPMAHIPH_00527	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPMAHIPH_00528	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HPMAHIPH_00529	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HPMAHIPH_00530	5.85e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HPMAHIPH_00531	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HPMAHIPH_00532	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_00533	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HPMAHIPH_00534	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPMAHIPH_00535	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
HPMAHIPH_00536	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_00537	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
HPMAHIPH_00538	8.14e-47	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HPMAHIPH_00542	1.19e-13	-	-	-	-	-	-	-	-
HPMAHIPH_00544	2.1e-71	-	-	-	-	-	-	-	-
HPMAHIPH_00545	1.42e-39	-	-	-	-	-	-	-	-
HPMAHIPH_00546	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HPMAHIPH_00547	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HPMAHIPH_00548	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HPMAHIPH_00549	2.05e-55	-	-	-	-	-	-	-	-
HPMAHIPH_00550	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HPMAHIPH_00551	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPMAHIPH_00552	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HPMAHIPH_00553	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HPMAHIPH_00554	1.51e-48	-	-	-	-	-	-	-	-
HPMAHIPH_00555	5.79e-21	-	-	-	-	-	-	-	-
HPMAHIPH_00556	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HPMAHIPH_00557	4e-40	-	-	-	S	-	-	-	CsbD-like
HPMAHIPH_00558	1.06e-53	-	-	-	-	-	-	-	-
HPMAHIPH_00559	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HPMAHIPH_00560	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HPMAHIPH_00561	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPMAHIPH_00562	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HPMAHIPH_00563	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HPMAHIPH_00564	1.52e-67	-	-	-	-	-	-	-	-
HPMAHIPH_00565	2.12e-57	-	-	-	-	-	-	-	-
HPMAHIPH_00566	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPMAHIPH_00567	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HPMAHIPH_00568	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HPMAHIPH_00569	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HPMAHIPH_00570	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HPMAHIPH_00571	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HPMAHIPH_00572	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HPMAHIPH_00573	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HPMAHIPH_00574	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPMAHIPH_00575	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HPMAHIPH_00576	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HPMAHIPH_00577	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HPMAHIPH_00578	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HPMAHIPH_00579	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HPMAHIPH_00580	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HPMAHIPH_00581	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HPMAHIPH_00582	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HPMAHIPH_00584	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPMAHIPH_00585	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_00586	5.51e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HPMAHIPH_00587	1.31e-109	-	-	-	T	-	-	-	Universal stress protein family
HPMAHIPH_00588	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_00589	4.86e-235	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPMAHIPH_00590	4.84e-230	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_00591	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HPMAHIPH_00592	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPMAHIPH_00593	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HPMAHIPH_00594	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPMAHIPH_00596	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HPMAHIPH_00597	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_00598	3.65e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
HPMAHIPH_00599	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HPMAHIPH_00600	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
HPMAHIPH_00601	1.59e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMAHIPH_00602	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HPMAHIPH_00603	1.66e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_00604	8.67e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HPMAHIPH_00605	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HPMAHIPH_00606	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_00607	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HPMAHIPH_00608	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_00609	6.79e-249	-	-	-	-	-	-	-	-
HPMAHIPH_00610	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HPMAHIPH_00611	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HPMAHIPH_00612	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HPMAHIPH_00613	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HPMAHIPH_00614	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HPMAHIPH_00615	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPMAHIPH_00616	1.13e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPMAHIPH_00617	1.1e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPMAHIPH_00618	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HPMAHIPH_00619	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HPMAHIPH_00620	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HPMAHIPH_00621	1.66e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HPMAHIPH_00622	9.07e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HPMAHIPH_00624	3.51e-59	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HPMAHIPH_00625	2.9e-94	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HPMAHIPH_00626	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HPMAHIPH_00627	2.31e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HPMAHIPH_00628	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
HPMAHIPH_00629	2.42e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00630	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HPMAHIPH_00631	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00632	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HPMAHIPH_00633	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HPMAHIPH_00634	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HPMAHIPH_00635	3.03e-40	-	-	-	-	-	-	-	-
HPMAHIPH_00636	2.37e-65	-	-	-	-	-	-	-	-
HPMAHIPH_00637	1.15e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HPMAHIPH_00638	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_00640	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HPMAHIPH_00641	6.02e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HPMAHIPH_00642	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HPMAHIPH_00643	2.14e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HPMAHIPH_00644	2.79e-181	-	-	-	-	-	-	-	-
HPMAHIPH_00645	7.79e-78	-	-	-	-	-	-	-	-
HPMAHIPH_00646	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HPMAHIPH_00647	7.87e-289	-	-	-	-	-	-	-	-
HPMAHIPH_00648	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HPMAHIPH_00649	1.47e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HPMAHIPH_00650	1.66e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPMAHIPH_00651	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPMAHIPH_00652	1.34e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HPMAHIPH_00653	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_00654	7.91e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HPMAHIPH_00655	3.69e-44	-	-	-	-	-	-	-	-
HPMAHIPH_00656	4.68e-11	-	-	-	-	-	-	-	-
HPMAHIPH_00657	4.8e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HPMAHIPH_00658	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPMAHIPH_00659	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMAHIPH_00660	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HPMAHIPH_00661	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPMAHIPH_00662	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HPMAHIPH_00663	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HPMAHIPH_00664	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00665	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPMAHIPH_00666	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPMAHIPH_00667	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPMAHIPH_00668	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HPMAHIPH_00669	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPMAHIPH_00670	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPMAHIPH_00671	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HPMAHIPH_00672	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPMAHIPH_00673	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPMAHIPH_00674	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HPMAHIPH_00675	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPMAHIPH_00676	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPMAHIPH_00677	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HPMAHIPH_00678	1.22e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HPMAHIPH_00679	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HPMAHIPH_00680	1.75e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HPMAHIPH_00681	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HPMAHIPH_00682	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_00683	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HPMAHIPH_00684	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HPMAHIPH_00685	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HPMAHIPH_00686	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMAHIPH_00687	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HPMAHIPH_00688	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPMAHIPH_00689	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPMAHIPH_00690	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00691	6.46e-109	-	-	-	-	-	-	-	-
HPMAHIPH_00692	1.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPMAHIPH_00693	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPMAHIPH_00694	3.71e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HPMAHIPH_00695	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMAHIPH_00696	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPMAHIPH_00697	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HPMAHIPH_00698	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HPMAHIPH_00699	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HPMAHIPH_00700	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HPMAHIPH_00701	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPMAHIPH_00702	3.11e-248	-	-	-	S	-	-	-	Helix-turn-helix domain
HPMAHIPH_00703	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPMAHIPH_00704	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HPMAHIPH_00705	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPMAHIPH_00706	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPMAHIPH_00707	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPMAHIPH_00708	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HPMAHIPH_00709	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HPMAHIPH_00710	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HPMAHIPH_00711	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HPMAHIPH_00712	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPMAHIPH_00713	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HPMAHIPH_00714	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HPMAHIPH_00716	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPMAHIPH_00717	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HPMAHIPH_00718	6.55e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPMAHIPH_00719	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HPMAHIPH_00720	1.13e-291	-	-	-	M	-	-	-	O-Antigen ligase
HPMAHIPH_00721	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HPMAHIPH_00722	5.71e-211	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_00723	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_00724	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HPMAHIPH_00725	1.94e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
HPMAHIPH_00726	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_00727	4.36e-263	-	-	-	-	-	-	-	-
HPMAHIPH_00728	6.08e-277	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HPMAHIPH_00729	5.25e-233	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPMAHIPH_00730	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HPMAHIPH_00731	4.44e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPMAHIPH_00732	8.87e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HPMAHIPH_00733	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00734	6.46e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HPMAHIPH_00735	6.66e-235	tanA	-	-	S	-	-	-	alpha beta
HPMAHIPH_00736	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPMAHIPH_00737	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HPMAHIPH_00738	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HPMAHIPH_00739	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HPMAHIPH_00740	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HPMAHIPH_00741	5.7e-146	-	-	-	GM	-	-	-	epimerase
HPMAHIPH_00742	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HPMAHIPH_00743	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00744	1.12e-273	-	-	-	S	-	-	-	membrane
HPMAHIPH_00745	1.55e-07	-	-	-	K	-	-	-	transcriptional regulator
HPMAHIPH_00746	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_00747	8.34e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_00748	7.51e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HPMAHIPH_00749	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HPMAHIPH_00750	3.69e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPMAHIPH_00751	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HPMAHIPH_00752	3.55e-146	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00753	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HPMAHIPH_00754	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_00755	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HPMAHIPH_00757	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPMAHIPH_00758	3.34e-165	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HPMAHIPH_00759	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_00761	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HPMAHIPH_00762	3.89e-94	-	-	-	K	-	-	-	MarR family
HPMAHIPH_00763	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMAHIPH_00764	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00765	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPMAHIPH_00766	5.21e-254	-	-	-	-	-	-	-	-
HPMAHIPH_00767	2.13e-255	-	-	-	-	-	-	-	-
HPMAHIPH_00768	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00769	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HPMAHIPH_00770	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPMAHIPH_00771	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPMAHIPH_00772	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HPMAHIPH_00773	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HPMAHIPH_00774	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HPMAHIPH_00775	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPMAHIPH_00776	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HPMAHIPH_00777	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPMAHIPH_00778	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HPMAHIPH_00779	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HPMAHIPH_00780	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HPMAHIPH_00781	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPMAHIPH_00782	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPMAHIPH_00783	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPMAHIPH_00784	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPMAHIPH_00785	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPMAHIPH_00786	3.57e-130	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPMAHIPH_00787	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPMAHIPH_00788	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HPMAHIPH_00789	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HPMAHIPH_00790	2.65e-213	-	-	-	G	-	-	-	Fructosamine kinase
HPMAHIPH_00791	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HPMAHIPH_00792	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPMAHIPH_00793	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPMAHIPH_00794	2.56e-76	-	-	-	-	-	-	-	-
HPMAHIPH_00795	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPMAHIPH_00796	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HPMAHIPH_00797	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HPMAHIPH_00798	4.78e-65	-	-	-	-	-	-	-	-
HPMAHIPH_00799	1.73e-67	-	-	-	-	-	-	-	-
HPMAHIPH_00800	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPMAHIPH_00801	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPMAHIPH_00802	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPMAHIPH_00803	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HPMAHIPH_00804	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPMAHIPH_00805	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HPMAHIPH_00806	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_00807	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPMAHIPH_00808	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HPMAHIPH_00809	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPMAHIPH_00810	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPMAHIPH_00811	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HPMAHIPH_00812	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HPMAHIPH_00813	2.56e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPMAHIPH_00814	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPMAHIPH_00815	5.99e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HPMAHIPH_00816	6.72e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPMAHIPH_00817	6.65e-121	-	-	-	-	-	-	-	-
HPMAHIPH_00818	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPMAHIPH_00819	0.0	-	-	-	G	-	-	-	Major Facilitator
HPMAHIPH_00820	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPMAHIPH_00821	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPMAHIPH_00822	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HPMAHIPH_00823	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HPMAHIPH_00824	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HPMAHIPH_00825	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HPMAHIPH_00826	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPMAHIPH_00827	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPMAHIPH_00828	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HPMAHIPH_00829	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HPMAHIPH_00830	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPMAHIPH_00831	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPMAHIPH_00832	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HPMAHIPH_00833	1.55e-193	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPMAHIPH_00834	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HPMAHIPH_00835	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HPMAHIPH_00836	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMAHIPH_00837	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HPMAHIPH_00838	3.65e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HPMAHIPH_00839	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HPMAHIPH_00840	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HPMAHIPH_00841	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HPMAHIPH_00842	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPMAHIPH_00843	1.83e-121	-	-	-	-	-	-	-	-
HPMAHIPH_00844	6.62e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HPMAHIPH_00845	1.01e-100	-	-	-	-	-	-	-	-
HPMAHIPH_00846	3.26e-88	-	-	-	-	-	-	-	-
HPMAHIPH_00847	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HPMAHIPH_00850	5.32e-12	-	-	-	S	-	-	-	Short C-terminal domain
HPMAHIPH_00851	6.67e-21	-	-	-	S	-	-	-	Belongs to the LOG family
HPMAHIPH_00852	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HPMAHIPH_00853	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HPMAHIPH_00854	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_00855	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HPMAHIPH_00856	1.12e-208	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00857	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HPMAHIPH_00858	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HPMAHIPH_00859	1.41e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HPMAHIPH_00860	1.7e-70	-	-	-	-	-	-	-	-
HPMAHIPH_00861	7.08e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HPMAHIPH_00862	2.11e-82	-	-	-	-	-	-	-	-
HPMAHIPH_00863	1.11e-111	-	-	-	-	-	-	-	-
HPMAHIPH_00864	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HPMAHIPH_00865	9.27e-74	-	-	-	-	-	-	-	-
HPMAHIPH_00866	4.79e-21	-	-	-	-	-	-	-	-
HPMAHIPH_00867	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00868	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HPMAHIPH_00869	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_00870	2.66e-155	-	-	-	S	-	-	-	membrane
HPMAHIPH_00871	2.55e-145	-	-	-	S	-	-	-	VIT family
HPMAHIPH_00872	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HPMAHIPH_00873	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HPMAHIPH_00874	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HPMAHIPH_00875	4.26e-54	-	-	-	-	-	-	-	-
HPMAHIPH_00876	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HPMAHIPH_00877	1.77e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HPMAHIPH_00878	2.07e-34	-	-	-	-	-	-	-	-
HPMAHIPH_00879	2.55e-65	-	-	-	-	-	-	-	-
HPMAHIPH_00880	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HPMAHIPH_00881	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HPMAHIPH_00882	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HPMAHIPH_00883	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HPMAHIPH_00884	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HPMAHIPH_00885	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HPMAHIPH_00886	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HPMAHIPH_00887	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HPMAHIPH_00888	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HPMAHIPH_00889	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HPMAHIPH_00890	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HPMAHIPH_00891	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPMAHIPH_00892	3.68e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HPMAHIPH_00893	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPMAHIPH_00894	6.94e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HPMAHIPH_00895	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HPMAHIPH_00896	1.58e-66	-	-	-	-	-	-	-	-
HPMAHIPH_00897	3.42e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HPMAHIPH_00898	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_00899	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HPMAHIPH_00900	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_00901	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPMAHIPH_00902	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HPMAHIPH_00903	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_00904	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HPMAHIPH_00905	4.45e-38	-	-	-	-	-	-	-	-
HPMAHIPH_00906	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HPMAHIPH_00907	1.44e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HPMAHIPH_00908	2.15e-71	-	-	-	-	-	-	-	-
HPMAHIPH_00909	5.77e-81	-	-	-	-	-	-	-	-
HPMAHIPH_00911	5.13e-138	-	-	-	-	-	-	-	-
HPMAHIPH_00912	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HPMAHIPH_00913	4.61e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HPMAHIPH_00914	2.85e-128	-	-	-	K	-	-	-	transcriptional regulator
HPMAHIPH_00915	5.05e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HPMAHIPH_00916	8.41e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPMAHIPH_00917	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HPMAHIPH_00918	3.28e-231	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPMAHIPH_00919	4.54e-54	-	-	-	-	-	-	-	-
HPMAHIPH_00921	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_00922	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HPMAHIPH_00923	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HPMAHIPH_00924	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPMAHIPH_00925	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPMAHIPH_00926	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HPMAHIPH_00927	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HPMAHIPH_00928	4.4e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HPMAHIPH_00929	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HPMAHIPH_00930	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HPMAHIPH_00932	2.77e-30	-	-	-	-	-	-	-	-
HPMAHIPH_00934	1.63e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_00935	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HPMAHIPH_00936	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_00937	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HPMAHIPH_00938	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HPMAHIPH_00939	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HPMAHIPH_00940	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HPMAHIPH_00941	2.55e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
HPMAHIPH_00942	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPMAHIPH_00943	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HPMAHIPH_00945	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HPMAHIPH_00946	1.88e-106	-	-	-	-	-	-	-	-
HPMAHIPH_00948	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPMAHIPH_00949	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HPMAHIPH_00950	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPMAHIPH_00951	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPMAHIPH_00952	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPMAHIPH_00953	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HPMAHIPH_00954	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HPMAHIPH_00955	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HPMAHIPH_00956	6.66e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HPMAHIPH_00957	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HPMAHIPH_00958	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HPMAHIPH_00959	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HPMAHIPH_00960	1.03e-34	-	-	-	-	-	-	-	-
HPMAHIPH_00961	5.45e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HPMAHIPH_00962	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HPMAHIPH_00963	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HPMAHIPH_00964	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_00965	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HPMAHIPH_00966	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HPMAHIPH_00967	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HPMAHIPH_00968	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HPMAHIPH_00969	3.32e-135	-	-	-	-	-	-	-	-
HPMAHIPH_00970	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HPMAHIPH_00971	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HPMAHIPH_00973	1.46e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HPMAHIPH_00974	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_00975	2.16e-199	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_00976	2.36e-100	-	-	-	K	-	-	-	MerR family regulatory protein
HPMAHIPH_00977	2.28e-103	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_00978	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HPMAHIPH_00979	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_00980	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HPMAHIPH_00981	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HPMAHIPH_00982	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HPMAHIPH_00983	3.03e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HPMAHIPH_00984	6.9e-197	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HPMAHIPH_00985	6.26e-101	-	-	-	-	-	-	-	-
HPMAHIPH_00986	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPMAHIPH_00987	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00988	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HPMAHIPH_00989	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HPMAHIPH_00990	2.6e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HPMAHIPH_00991	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HPMAHIPH_00992	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_00993	1.53e-198	-	-	-	S	-	-	-	Putative adhesin
HPMAHIPH_00994	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HPMAHIPH_00995	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_00996	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
HPMAHIPH_00997	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HPMAHIPH_00998	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_00999	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_01000	1.11e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HPMAHIPH_01001	1.2e-301	-	-	-	EK	-	-	-	Aminotransferase, class I
HPMAHIPH_01002	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_01003	1.74e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_01004	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HPMAHIPH_01005	3.35e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HPMAHIPH_01006	2.88e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HPMAHIPH_01007	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HPMAHIPH_01008	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HPMAHIPH_01009	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HPMAHIPH_01010	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HPMAHIPH_01011	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPMAHIPH_01012	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HPMAHIPH_01013	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPMAHIPH_01014	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPMAHIPH_01015	8.03e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HPMAHIPH_01016	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HPMAHIPH_01017	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HPMAHIPH_01018	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HPMAHIPH_01019	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HPMAHIPH_01020	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HPMAHIPH_01021	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HPMAHIPH_01022	9.65e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HPMAHIPH_01023	2.12e-72	-	-	-	-	-	-	-	-
HPMAHIPH_01024	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMAHIPH_01025	2.89e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HPMAHIPH_01026	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HPMAHIPH_01027	2.27e-257	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HPMAHIPH_01028	5.74e-211	-	-	-	-	-	-	-	-
HPMAHIPH_01029	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HPMAHIPH_01030	1.15e-147	-	-	-	-	-	-	-	-
HPMAHIPH_01031	7.62e-270	xylR	-	-	GK	-	-	-	ROK family
HPMAHIPH_01032	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HPMAHIPH_01033	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPMAHIPH_01034	6.79e-53	-	-	-	-	-	-	-	-
HPMAHIPH_01036	3.82e-206	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPMAHIPH_01037	6.2e-107	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMAHIPH_01039	2.31e-118	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPMAHIPH_01040	5.35e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HPMAHIPH_01042	8.42e-82	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase family
HPMAHIPH_01043	2.09e-94	-	-	-	S	-	-	-	Fic/DOC family
HPMAHIPH_01044	5.99e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HPMAHIPH_01046	1.51e-42	xerD_2	-	-	L	-	-	-	Phage integrase family
HPMAHIPH_01047	2.71e-209	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HPMAHIPH_01048	1.62e-30	-	-	-	-	-	-	-	-
HPMAHIPH_01051	1.04e-178	ydbD	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
HPMAHIPH_01055	5.14e-44	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HPMAHIPH_01056	3.25e-96	-	-	-	L	-	-	-	Transposase DDE domain
HPMAHIPH_01057	2.19e-27	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HPMAHIPH_01058	2.28e-61	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPMAHIPH_01059	1.57e-99	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_01062	5.83e-87	repB	-	-	L	-	-	-	Initiator Replication protein
HPMAHIPH_01064	1.41e-63	-	-	-	O	-	-	-	OsmC-like protein
HPMAHIPH_01065	9.72e-73	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HPMAHIPH_01069	1.73e-63	-	-	-	S	-	-	-	Fic/DOC family
HPMAHIPH_01070	1.35e-93	-	-	-	-	-	-	-	-
HPMAHIPH_01071	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HPMAHIPH_01072	2.07e-118	-	-	-	-	-	-	-	-
HPMAHIPH_01073	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPMAHIPH_01074	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPMAHIPH_01075	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPMAHIPH_01076	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPMAHIPH_01077	1.03e-60	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HPMAHIPH_01078	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPMAHIPH_01079	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HPMAHIPH_01080	1.86e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPMAHIPH_01081	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPMAHIPH_01082	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HPMAHIPH_01083	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPMAHIPH_01084	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HPMAHIPH_01085	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPMAHIPH_01086	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPMAHIPH_01087	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HPMAHIPH_01088	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HPMAHIPH_01089	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HPMAHIPH_01090	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPMAHIPH_01091	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HPMAHIPH_01092	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HPMAHIPH_01093	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPMAHIPH_01094	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPMAHIPH_01095	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HPMAHIPH_01096	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPMAHIPH_01097	1.6e-96	-	-	-	-	-	-	-	-
HPMAHIPH_01098	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_01099	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HPMAHIPH_01100	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HPMAHIPH_01101	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HPMAHIPH_01102	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HPMAHIPH_01103	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HPMAHIPH_01104	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPMAHIPH_01105	1.27e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HPMAHIPH_01106	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HPMAHIPH_01107	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HPMAHIPH_01108	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HPMAHIPH_01109	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HPMAHIPH_01110	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HPMAHIPH_01112	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HPMAHIPH_01113	1.91e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPMAHIPH_01114	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HPMAHIPH_01115	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HPMAHIPH_01116	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HPMAHIPH_01117	2.54e-112	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HPMAHIPH_01118	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPMAHIPH_01119	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HPMAHIPH_01120	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HPMAHIPH_01121	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPMAHIPH_01122	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HPMAHIPH_01123	1.11e-84	-	-	-	-	-	-	-	-
HPMAHIPH_01124	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HPMAHIPH_01125	1.6e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPMAHIPH_01126	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPMAHIPH_01127	1.02e-155	-	-	-	S	-	-	-	repeat protein
HPMAHIPH_01128	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HPMAHIPH_01129	0.0	-	-	-	N	-	-	-	domain, Protein
HPMAHIPH_01130	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HPMAHIPH_01131	5.92e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_01132	9.37e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HPMAHIPH_01133	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HPMAHIPH_01134	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPMAHIPH_01135	5.78e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HPMAHIPH_01136	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HPMAHIPH_01137	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPMAHIPH_01138	7.74e-47	-	-	-	-	-	-	-	-
HPMAHIPH_01139	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HPMAHIPH_01140	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPMAHIPH_01141	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPMAHIPH_01142	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HPMAHIPH_01143	8.38e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HPMAHIPH_01144	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HPMAHIPH_01145	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPMAHIPH_01146	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPMAHIPH_01147	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPMAHIPH_01148	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPMAHIPH_01149	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPMAHIPH_01150	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPMAHIPH_01151	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPMAHIPH_01152	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HPMAHIPH_01153	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HPMAHIPH_01154	2.58e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPMAHIPH_01155	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HPMAHIPH_01156	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HPMAHIPH_01157	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HPMAHIPH_01158	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HPMAHIPH_01159	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPMAHIPH_01160	1.76e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HPMAHIPH_01161	8.82e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HPMAHIPH_01163	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HPMAHIPH_01164	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPMAHIPH_01165	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HPMAHIPH_01166	1.55e-74	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HPMAHIPH_01167	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HPMAHIPH_01168	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HPMAHIPH_01169	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPMAHIPH_01170	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPMAHIPH_01171	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HPMAHIPH_01172	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HPMAHIPH_01173	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HPMAHIPH_01174	7.52e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HPMAHIPH_01175	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPMAHIPH_01176	5.37e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPMAHIPH_01177	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HPMAHIPH_01178	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HPMAHIPH_01197	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPMAHIPH_01198	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HPMAHIPH_01199	1.86e-287	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HPMAHIPH_01200	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HPMAHIPH_01201	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPMAHIPH_01202	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HPMAHIPH_01203	2.34e-284	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HPMAHIPH_01204	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPMAHIPH_01205	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HPMAHIPH_01206	5.6e-41	-	-	-	-	-	-	-	-
HPMAHIPH_01207	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HPMAHIPH_01208	2.5e-132	-	-	-	L	-	-	-	Integrase
HPMAHIPH_01209	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HPMAHIPH_01211	2.44e-202	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HPMAHIPH_01212	5.83e-182	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HPMAHIPH_01213	1.91e-57	-	-	-	-	-	-	-	-
HPMAHIPH_01214	4.65e-78	-	-	-	-	-	-	-	-
HPMAHIPH_01215	2.63e-69	-	-	-	-	-	-	-	-
HPMAHIPH_01216	2.73e-232	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HPMAHIPH_01217	3.15e-17	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
HPMAHIPH_01218	9.39e-191	-	-	-	-	-	-	-	-
HPMAHIPH_01219	1.41e-61	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HPMAHIPH_01221	6.36e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HPMAHIPH_01222	8.77e-98	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HPMAHIPH_01224	1.95e-122	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HPMAHIPH_01225	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HPMAHIPH_01226	0.0	nox	-	-	C	-	-	-	NADH oxidase
HPMAHIPH_01227	2.6e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HPMAHIPH_01228	4.95e-310	-	-	-	-	-	-	-	-
HPMAHIPH_01229	3.39e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HPMAHIPH_01230	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HPMAHIPH_01231	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HPMAHIPH_01232	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
HPMAHIPH_01233	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPMAHIPH_01234	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HPMAHIPH_01235	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HPMAHIPH_01236	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPMAHIPH_01237	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HPMAHIPH_01238	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPMAHIPH_01239	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPMAHIPH_01240	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HPMAHIPH_01241	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HPMAHIPH_01242	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPMAHIPH_01243	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPMAHIPH_01244	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPMAHIPH_01245	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPMAHIPH_01246	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HPMAHIPH_01247	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HPMAHIPH_01248	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HPMAHIPH_01249	1.86e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HPMAHIPH_01250	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HPMAHIPH_01251	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_01252	3.64e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMAHIPH_01253	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPMAHIPH_01255	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HPMAHIPH_01256	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HPMAHIPH_01257	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPMAHIPH_01258	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HPMAHIPH_01259	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPMAHIPH_01260	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPMAHIPH_01261	5.11e-171	-	-	-	-	-	-	-	-
HPMAHIPH_01262	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HPMAHIPH_01263	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HPMAHIPH_01264	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HPMAHIPH_01265	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPMAHIPH_01266	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPMAHIPH_01267	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HPMAHIPH_01268	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_01269	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_01270	7.98e-137	-	-	-	-	-	-	-	-
HPMAHIPH_01271	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_01272	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPMAHIPH_01273	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HPMAHIPH_01274	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HPMAHIPH_01275	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_01276	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HPMAHIPH_01277	1.46e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HPMAHIPH_01278	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HPMAHIPH_01279	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HPMAHIPH_01280	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HPMAHIPH_01281	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_01282	2.31e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HPMAHIPH_01283	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPMAHIPH_01284	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HPMAHIPH_01285	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPMAHIPH_01286	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPMAHIPH_01287	3.15e-158	-	-	-	T	-	-	-	EAL domain
HPMAHIPH_01288	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_01289	7.01e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_01290	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HPMAHIPH_01291	3.38e-70	-	-	-	-	-	-	-	-
HPMAHIPH_01292	2.05e-94	-	-	-	-	-	-	-	-
HPMAHIPH_01293	7.06e-169	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HPMAHIPH_01294	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HPMAHIPH_01295	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HPMAHIPH_01296	1.06e-95	-	-	-	-	-	-	-	-
HPMAHIPH_01298	7.69e-98	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HPMAHIPH_01301	2.51e-116	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMAHIPH_01302	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HPMAHIPH_01303	2.06e-199	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HPMAHIPH_01304	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HPMAHIPH_01305	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HPMAHIPH_01306	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HPMAHIPH_01307	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HPMAHIPH_01308	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HPMAHIPH_01309	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_01311	1.79e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HPMAHIPH_01312	1.31e-64	-	-	-	-	-	-	-	-
HPMAHIPH_01313	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HPMAHIPH_01314	1.9e-176	-	-	-	F	-	-	-	NUDIX domain
HPMAHIPH_01315	2.68e-32	-	-	-	-	-	-	-	-
HPMAHIPH_01317	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_01318	1.05e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HPMAHIPH_01319	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HPMAHIPH_01320	2.29e-48	-	-	-	-	-	-	-	-
HPMAHIPH_01321	1.11e-45	-	-	-	-	-	-	-	-
HPMAHIPH_01322	4.98e-173	-	-	-	T	-	-	-	diguanylate cyclase
HPMAHIPH_01323	1.46e-38	-	-	-	T	-	-	-	diguanylate cyclase
HPMAHIPH_01324	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HPMAHIPH_01325	5.35e-139	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HPMAHIPH_01326	1.01e-42	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HPMAHIPH_01327	8.56e-74	-	-	-	S	-	-	-	Phage integrase family
HPMAHIPH_01330	1.75e-43	-	-	-	-	-	-	-	-
HPMAHIPH_01331	1.14e-180	-	-	-	Q	-	-	-	Methyltransferase
HPMAHIPH_01332	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HPMAHIPH_01333	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPMAHIPH_01334	7.9e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_01335	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPMAHIPH_01336	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HPMAHIPH_01337	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HPMAHIPH_01338	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_01339	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPMAHIPH_01340	6.62e-62	-	-	-	-	-	-	-	-
HPMAHIPH_01341	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPMAHIPH_01342	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HPMAHIPH_01343	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPMAHIPH_01344	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HPMAHIPH_01345	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HPMAHIPH_01346	0.0	cps4J	-	-	S	-	-	-	MatE
HPMAHIPH_01347	9.73e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMAHIPH_01348	5.09e-238	-	-	-	-	-	-	-	-
HPMAHIPH_01349	1.99e-237	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HPMAHIPH_01350	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HPMAHIPH_01351	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HPMAHIPH_01352	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HPMAHIPH_01353	9.18e-188	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HPMAHIPH_01354	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HPMAHIPH_01355	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HPMAHIPH_01356	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPMAHIPH_01357	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_01358	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_01359	5.12e-31	-	-	-	-	-	-	-	-
HPMAHIPH_01360	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HPMAHIPH_01361	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HPMAHIPH_01362	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HPMAHIPH_01363	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPMAHIPH_01364	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPMAHIPH_01365	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPMAHIPH_01366	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMAHIPH_01367	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPMAHIPH_01368	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPMAHIPH_01369	1.82e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_01370	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPMAHIPH_01371	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HPMAHIPH_01372	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HPMAHIPH_01373	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HPMAHIPH_01374	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HPMAHIPH_01375	3.85e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HPMAHIPH_01376	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HPMAHIPH_01377	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPMAHIPH_01378	6.06e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HPMAHIPH_01379	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HPMAHIPH_01380	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HPMAHIPH_01381	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HPMAHIPH_01382	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_01383	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HPMAHIPH_01384	9.51e-135	-	-	-	-	-	-	-	-
HPMAHIPH_01388	5.7e-109	-	-	-	L	-	-	-	Resolvase, N terminal domain
HPMAHIPH_01389	1.18e-211	-	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HPMAHIPH_01390	1.2e-117	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HPMAHIPH_01391	1.29e-227	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HPMAHIPH_01392	9.24e-56	-	-	-	-	-	-	-	-
HPMAHIPH_01393	1.5e-226	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HPMAHIPH_01394	6.83e-60	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_01395	5.6e-121	degV	-	-	S	-	-	-	EDD domain protein, DegV family
HPMAHIPH_01396	5.31e-119	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPMAHIPH_01397	3.05e-225	-	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HPMAHIPH_01398	1.42e-65	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_01401	4.33e-60	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HPMAHIPH_01402	3.14e-316	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HPMAHIPH_01403	5.25e-73	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPMAHIPH_01404	8.64e-67	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
HPMAHIPH_01405	1.58e-16	-	-	-	-	-	-	-	-
HPMAHIPH_01406	1.23e-75	-	-	-	-	-	-	-	-
HPMAHIPH_01407	1.86e-210	-	-	-	-	-	-	-	-
HPMAHIPH_01408	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_01409	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HPMAHIPH_01410	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HPMAHIPH_01411	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HPMAHIPH_01412	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HPMAHIPH_01413	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_01414	2.66e-172	-	-	-	-	-	-	-	-
HPMAHIPH_01415	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HPMAHIPH_01416	2.82e-105	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPMAHIPH_01417	1.16e-294	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPMAHIPH_01418	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HPMAHIPH_01419	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HPMAHIPH_01420	1.18e-225	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPMAHIPH_01421	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPMAHIPH_01422	1.22e-200	ccpB	-	-	K	-	-	-	lacI family
HPMAHIPH_01423	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_01424	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPMAHIPH_01425	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HPMAHIPH_01426	1.81e-126	-	-	-	C	-	-	-	Nitroreductase family
HPMAHIPH_01427	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HPMAHIPH_01428	5.49e-249	-	-	-	S	-	-	-	domain, Protein
HPMAHIPH_01429	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_01430	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HPMAHIPH_01431	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HPMAHIPH_01432	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPMAHIPH_01433	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_01434	0.0	-	-	-	M	-	-	-	domain protein
HPMAHIPH_01437	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HPMAHIPH_01438	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HPMAHIPH_01442	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HPMAHIPH_01443	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HPMAHIPH_01444	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HPMAHIPH_01445	1.2e-242	ysdE	-	-	P	-	-	-	Citrate transporter
HPMAHIPH_01446	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HPMAHIPH_01447	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPMAHIPH_01448	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPMAHIPH_01449	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HPMAHIPH_01450	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPMAHIPH_01451	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPMAHIPH_01452	4.33e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPMAHIPH_01453	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HPMAHIPH_01454	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HPMAHIPH_01455	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HPMAHIPH_01456	6.25e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HPMAHIPH_01457	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HPMAHIPH_01458	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPMAHIPH_01460	2.19e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_01461	3.38e-33	-	-	-	-	-	-	-	-
HPMAHIPH_01462	5e-42	-	-	-	S	-	-	-	Short C-terminal domain
HPMAHIPH_01463	4.48e-64	-	-	-	E	-	-	-	Zn peptidase
HPMAHIPH_01464	3.31e-22	-	-	-	K	-	-	-	Peptidase S24-like
HPMAHIPH_01466	1.48e-109	-	-	-	S	-	-	-	DNA binding
HPMAHIPH_01468	1.7e-05	-	-	-	-	-	-	-	-
HPMAHIPH_01470	4.56e-71	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPMAHIPH_01471	2.01e-36	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HPMAHIPH_01472	3.23e-75	-	-	-	S	-	-	-	Putative HNHc nuclease
HPMAHIPH_01474	3.59e-44	-	-	-	-	-	-	-	-
HPMAHIPH_01475	3.9e-50	-	-	-	-	-	-	-	-
HPMAHIPH_01480	8.32e-107	-	-	-	S	-	-	-	methyltransferase activity
HPMAHIPH_01485	2.79e-138	-	-	-	D	-	-	-	AAA domain
HPMAHIPH_01487	3.75e-22	-	-	-	M	-	-	-	Lysin motif
HPMAHIPH_01488	2.84e-25	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HPMAHIPH_01495	1.94e-297	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
HPMAHIPH_01496	9.04e-43	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPMAHIPH_01497	9.91e-63	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPMAHIPH_01498	1.95e-05	-	-	-	M	-	-	-	domain protein
HPMAHIPH_01500	7.22e-92	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HPMAHIPH_01501	1.26e-207	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HPMAHIPH_01502	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HPMAHIPH_01503	1.75e-05	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPMAHIPH_01505	9.76e-245	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HPMAHIPH_01506	6.15e-30	-	-	-	-	-	-	-	-
HPMAHIPH_01507	3.94e-78	-	-	-	-	-	-	-	-
HPMAHIPH_01511	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HPMAHIPH_01512	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_01513	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPMAHIPH_01514	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HPMAHIPH_01515	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_01516	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_01517	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HPMAHIPH_01518	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HPMAHIPH_01519	5.04e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HPMAHIPH_01520	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPMAHIPH_01521	9.01e-155	-	-	-	S	-	-	-	Membrane
HPMAHIPH_01522	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HPMAHIPH_01523	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HPMAHIPH_01524	1.05e-142	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_01525	5.94e-162	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HPMAHIPH_01526	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HPMAHIPH_01527	7.8e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HPMAHIPH_01528	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HPMAHIPH_01529	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HPMAHIPH_01530	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_01531	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HPMAHIPH_01532	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HPMAHIPH_01534	4.96e-88	-	-	-	M	-	-	-	LysM domain
HPMAHIPH_01535	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HPMAHIPH_01536	6.21e-39	-	-	-	-	-	-	-	-
HPMAHIPH_01537	2.43e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HPMAHIPH_01538	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPMAHIPH_01539	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HPMAHIPH_01540	6.45e-111	-	-	-	-	-	-	-	-
HPMAHIPH_01541	2.29e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPMAHIPH_01542	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HPMAHIPH_01543	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HPMAHIPH_01544	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPMAHIPH_01545	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HPMAHIPH_01546	1.24e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HPMAHIPH_01547	6.24e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HPMAHIPH_01548	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HPMAHIPH_01549	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HPMAHIPH_01550	6.34e-257	-	-	-	-	-	-	-	-
HPMAHIPH_01551	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HPMAHIPH_01552	3.36e-62	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HPMAHIPH_01553	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HPMAHIPH_01554	7.03e-62	-	-	-	-	-	-	-	-
HPMAHIPH_01555	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPMAHIPH_01556	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HPMAHIPH_01557	9.8e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_01558	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HPMAHIPH_01559	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HPMAHIPH_01560	1.15e-43	-	-	-	-	-	-	-	-
HPMAHIPH_01562	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HPMAHIPH_01563	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HPMAHIPH_01564	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HPMAHIPH_01565	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HPMAHIPH_01566	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_01567	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HPMAHIPH_01568	2.56e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_01569	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
HPMAHIPH_01570	1.4e-82	-	-	-	-	-	-	-	-
HPMAHIPH_01571	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_01572	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_01573	2.76e-196	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HPMAHIPH_01574	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_01575	7.99e-292	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HPMAHIPH_01576	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPMAHIPH_01577	1.54e-144	-	-	-	-	-	-	-	-
HPMAHIPH_01578	2.39e-247	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HPMAHIPH_01579	1.29e-183	-	-	-	S	-	-	-	Peptidase_C39 like family
HPMAHIPH_01580	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HPMAHIPH_01581	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HPMAHIPH_01582	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HPMAHIPH_01583	1.32e-120	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPMAHIPH_01584	2.9e-253	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPMAHIPH_01585	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HPMAHIPH_01586	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPMAHIPH_01587	4.26e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPMAHIPH_01588	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPMAHIPH_01589	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPMAHIPH_01590	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HPMAHIPH_01591	3.86e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPMAHIPH_01592	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPMAHIPH_01593	1.09e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPMAHIPH_01594	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HPMAHIPH_01595	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HPMAHIPH_01596	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HPMAHIPH_01597	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HPMAHIPH_01598	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HPMAHIPH_01599	2.05e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_01600	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HPMAHIPH_01601	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPMAHIPH_01602	4.89e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPMAHIPH_01603	1.45e-46	-	-	-	-	-	-	-	-
HPMAHIPH_01604	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HPMAHIPH_01605	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HPMAHIPH_01606	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPMAHIPH_01607	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPMAHIPH_01608	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPMAHIPH_01609	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPMAHIPH_01610	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_01611	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HPMAHIPH_01612	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HPMAHIPH_01613	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_01614	1.43e-250	-	-	-	M	-	-	-	MucBP domain
HPMAHIPH_01615	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_01617	1.75e-91	-	-	-	-	-	-	-	-
HPMAHIPH_01618	1.98e-202	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HPMAHIPH_01619	1.02e-177	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HPMAHIPH_01620	7.48e-206	-	-	-	L	-	-	-	DnaD domain protein
HPMAHIPH_01623	3.27e-24	-	-	-	-	-	-	-	-
HPMAHIPH_01625	2.08e-99	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HPMAHIPH_01626	1.78e-305	-	-	-	S	-	-	-	Terminase-like family
HPMAHIPH_01627	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPMAHIPH_01628	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
HPMAHIPH_01629	3.05e-41	-	-	-	-	-	-	-	-
HPMAHIPH_01632	4.9e-65	-	-	-	-	-	-	-	-
HPMAHIPH_01633	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
HPMAHIPH_01635	5.01e-69	-	-	-	-	-	-	-	-
HPMAHIPH_01636	9.63e-68	-	-	-	-	-	-	-	-
HPMAHIPH_01637	8.86e-114	-	-	-	-	-	-	-	-
HPMAHIPH_01638	4.96e-72	-	-	-	-	-	-	-	-
HPMAHIPH_01639	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HPMAHIPH_01640	1.42e-83	-	-	-	-	-	-	-	-
HPMAHIPH_01641	3.76e-32	-	-	-	-	-	-	-	-
HPMAHIPH_01642	0.0	-	-	-	D	-	-	-	domain protein
HPMAHIPH_01643	2.29e-81	-	-	-	-	-	-	-	-
HPMAHIPH_01644	0.0	-	-	-	LM	-	-	-	DNA recombination
HPMAHIPH_01645	6.19e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HPMAHIPH_01647	7.37e-231	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HPMAHIPH_01651	6.67e-109	-	-	-	-	-	-	-	-
HPMAHIPH_01652	2.53e-122	-	-	-	S	-	-	-	AAA domain
HPMAHIPH_01653	2.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HPMAHIPH_01654	1.51e-65	-	-	-	L	-	-	-	DnaD domain protein
HPMAHIPH_01655	1.41e-86	-	-	-	S	-	-	-	DNA helicase activity
HPMAHIPH_01657	5.37e-06	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPMAHIPH_01658	4.28e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HPMAHIPH_01659	1.57e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HPMAHIPH_01662	2.49e-21	-	-	-	-	-	-	-	-
HPMAHIPH_01664	2.59e-56	-	-	-	-	-	-	-	-
HPMAHIPH_01666	1.76e-24	-	-	-	-	-	-	-	-
HPMAHIPH_01668	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPMAHIPH_01669	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HPMAHIPH_01670	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPMAHIPH_01671	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPMAHIPH_01672	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPMAHIPH_01673	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HPMAHIPH_01674	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPMAHIPH_01675	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPMAHIPH_01676	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HPMAHIPH_01677	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPMAHIPH_01678	4.35e-123	-	-	-	S	-	-	-	SdpI/YhfL protein family
HPMAHIPH_01679	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPMAHIPH_01680	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HPMAHIPH_01681	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HPMAHIPH_01682	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HPMAHIPH_01683	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HPMAHIPH_01684	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HPMAHIPH_01685	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPMAHIPH_01686	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPMAHIPH_01687	2.62e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HPMAHIPH_01688	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HPMAHIPH_01689	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HPMAHIPH_01690	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HPMAHIPH_01691	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPMAHIPH_01692	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HPMAHIPH_01693	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPMAHIPH_01694	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HPMAHIPH_01695	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HPMAHIPH_01696	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HPMAHIPH_01697	1.81e-113	-	-	-	-	-	-	-	-
HPMAHIPH_01698	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HPMAHIPH_01699	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HPMAHIPH_01700	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HPMAHIPH_01701	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPMAHIPH_01702	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HPMAHIPH_01703	2.76e-74	-	-	-	-	-	-	-	-
HPMAHIPH_01704	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPMAHIPH_01705	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HPMAHIPH_01706	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPMAHIPH_01707	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPMAHIPH_01708	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HPMAHIPH_01709	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HPMAHIPH_01710	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPMAHIPH_01711	2.25e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPMAHIPH_01712	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPMAHIPH_01713	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPMAHIPH_01714	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HPMAHIPH_01715	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HPMAHIPH_01716	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HPMAHIPH_01717	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HPMAHIPH_01718	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HPMAHIPH_01719	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPMAHIPH_01720	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HPMAHIPH_01721	6.34e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HPMAHIPH_01722	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HPMAHIPH_01723	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HPMAHIPH_01724	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HPMAHIPH_01725	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HPMAHIPH_01726	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HPMAHIPH_01727	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPMAHIPH_01728	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HPMAHIPH_01729	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPMAHIPH_01730	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HPMAHIPH_01731	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_01732	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_01733	2.08e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HPMAHIPH_01734	7.9e-72	-	-	-	-	-	-	-	-
HPMAHIPH_01735	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPMAHIPH_01736	1e-14	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_01737	8.12e-104	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_01738	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_01739	1.94e-247	-	-	-	S	-	-	-	Fn3-like domain
HPMAHIPH_01740	1.65e-80	-	-	-	-	-	-	-	-
HPMAHIPH_01741	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_01742	4.97e-307	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HPMAHIPH_01743	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_01744	1.35e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HPMAHIPH_01745	3.39e-138	-	-	-	-	-	-	-	-
HPMAHIPH_01746	3.01e-136	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HPMAHIPH_01747	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPMAHIPH_01748	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPMAHIPH_01749	5.86e-109	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HPMAHIPH_01750	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPMAHIPH_01751	0.0	-	-	-	S	-	-	-	membrane
HPMAHIPH_01752	1.22e-25	-	-	-	S	-	-	-	NUDIX domain
HPMAHIPH_01753	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPMAHIPH_01754	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HPMAHIPH_01755	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HPMAHIPH_01756	1.05e-127	-	-	-	-	-	-	-	-
HPMAHIPH_01757	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPMAHIPH_01758	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HPMAHIPH_01759	9.36e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_01760	2.81e-232	-	-	-	M	-	-	-	Peptidase family S41
HPMAHIPH_01761	6.35e-274	-	-	-	-	-	-	-	-
HPMAHIPH_01762	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPMAHIPH_01763	0.0	yhaN	-	-	L	-	-	-	AAA domain
HPMAHIPH_01764	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HPMAHIPH_01765	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HPMAHIPH_01766	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HPMAHIPH_01767	2.43e-18	-	-	-	-	-	-	-	-
HPMAHIPH_01768	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HPMAHIPH_01769	4.59e-270	arcT	-	-	E	-	-	-	Aminotransferase
HPMAHIPH_01770	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HPMAHIPH_01771	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HPMAHIPH_01772	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPMAHIPH_01773	8.15e-52	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HPMAHIPH_01774	1.36e-70	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HPMAHIPH_01775	1.28e-273	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HPMAHIPH_01776	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_01777	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_01778	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_01779	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HPMAHIPH_01780	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HPMAHIPH_01781	0.0	celR	-	-	K	-	-	-	PRD domain
HPMAHIPH_01782	6.25e-138	-	-	-	-	-	-	-	-
HPMAHIPH_01783	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPMAHIPH_01784	3.81e-105	-	-	-	-	-	-	-	-
HPMAHIPH_01785	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HPMAHIPH_01786	7.02e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HPMAHIPH_01789	1.79e-42	-	-	-	-	-	-	-	-
HPMAHIPH_01790	1.8e-315	dinF	-	-	V	-	-	-	MatE
HPMAHIPH_01791	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HPMAHIPH_01792	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HPMAHIPH_01793	5.68e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HPMAHIPH_01794	2.24e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HPMAHIPH_01795	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HPMAHIPH_01796	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HPMAHIPH_01797	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPMAHIPH_01798	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HPMAHIPH_01799	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HPMAHIPH_01800	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HPMAHIPH_01801	3.89e-237	-	-	-	-	-	-	-	-
HPMAHIPH_01802	9.03e-16	-	-	-	-	-	-	-	-
HPMAHIPH_01803	4.29e-87	-	-	-	-	-	-	-	-
HPMAHIPH_01806	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HPMAHIPH_01807	7.12e-62	-	-	-	-	-	-	-	-
HPMAHIPH_01808	8.82e-119	-	-	-	-	-	-	-	-
HPMAHIPH_01809	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_01810	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_01811	4.56e-78	-	-	-	-	-	-	-	-
HPMAHIPH_01812	5.37e-74	-	-	-	-	-	-	-	-
HPMAHIPH_01813	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HPMAHIPH_01814	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HPMAHIPH_01815	7.83e-140	-	-	-	-	-	-	-	-
HPMAHIPH_01816	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_01817	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPMAHIPH_01818	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_01819	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_01820	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPMAHIPH_01821	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HPMAHIPH_01822	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_01823	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HPMAHIPH_01825	7.61e-316	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HPMAHIPH_01826	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPMAHIPH_01827	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HPMAHIPH_01828	1.56e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HPMAHIPH_01829	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HPMAHIPH_01830	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_01831	4.59e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_01832	4.15e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HPMAHIPH_01833	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPMAHIPH_01834	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HPMAHIPH_01835	1.83e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPMAHIPH_01836	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HPMAHIPH_01837	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HPMAHIPH_01838	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMAHIPH_01839	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HPMAHIPH_01840	3.54e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HPMAHIPH_01841	9.32e-40	-	-	-	-	-	-	-	-
HPMAHIPH_01842	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HPMAHIPH_01843	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HPMAHIPH_01844	3.82e-172	-	-	-	S	-	-	-	Pfam Methyltransferase
HPMAHIPH_01845	1.74e-197	-	-	-	S	-	-	-	Pfam Methyltransferase
HPMAHIPH_01846	2.87e-308	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HPMAHIPH_01847	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_01848	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPMAHIPH_01849	5.79e-158	-	-	-	-	-	-	-	-
HPMAHIPH_01850	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HPMAHIPH_01851	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HPMAHIPH_01852	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HPMAHIPH_01853	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HPMAHIPH_01854	6.28e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HPMAHIPH_01856	2.52e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HPMAHIPH_01857	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_01858	1.25e-124	-	-	-	-	-	-	-	-
HPMAHIPH_01859	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HPMAHIPH_01860	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HPMAHIPH_01872	3.46e-07	-	-	-	L	ko:K07487	-	ko00000	Transposase
HPMAHIPH_01873	1.67e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_01874	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HPMAHIPH_01875	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HPMAHIPH_01876	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HPMAHIPH_01877	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HPMAHIPH_01878	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HPMAHIPH_01879	2.7e-168	-	-	-	-	-	-	-	-
HPMAHIPH_01880	2.39e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HPMAHIPH_01881	3.31e-35	-	-	-	-	-	-	-	-
HPMAHIPH_01882	1.13e-40	-	-	-	-	-	-	-	-
HPMAHIPH_01883	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HPMAHIPH_01884	3.68e-69	-	-	-	-	-	-	-	-
HPMAHIPH_01885	2.5e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HPMAHIPH_01886	0.0	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HPMAHIPH_01887	1.36e-90	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_01888	7.71e-39	-	-	-	M	-	-	-	domain protein
HPMAHIPH_01889	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HPMAHIPH_01890	8.08e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_01891	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HPMAHIPH_01892	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HPMAHIPH_01893	1.01e-26	-	-	-	-	-	-	-	-
HPMAHIPH_01894	7.94e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HPMAHIPH_01895	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HPMAHIPH_01896	2.59e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HPMAHIPH_01897	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HPMAHIPH_01898	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HPMAHIPH_01899	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPMAHIPH_01900	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HPMAHIPH_01901	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HPMAHIPH_01902	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HPMAHIPH_01903	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HPMAHIPH_01904	1.73e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HPMAHIPH_01905	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HPMAHIPH_01906	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HPMAHIPH_01907	7.37e-08	-	-	-	-	-	-	-	-
HPMAHIPH_01910	2.5e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HPMAHIPH_01911	1.58e-81	-	-	-	-	-	-	-	-
HPMAHIPH_01912	6.14e-122	-	-	-	-	-	-	-	-
HPMAHIPH_01913	3.51e-72	-	-	-	L	-	-	-	Helix-turn-helix domain
HPMAHIPH_01914	2.47e-109	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HPMAHIPH_01915	9.29e-62	-	-	-	L	-	-	-	DnaD domain protein
HPMAHIPH_01916	9.12e-80	-	-	-	-	-	-	-	-
HPMAHIPH_01917	4.61e-69	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HPMAHIPH_01919	4.42e-51	-	-	-	S	-	-	-	Bacteriophage holin
HPMAHIPH_01920	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HPMAHIPH_01921	1.78e-88	-	-	-	L	-	-	-	nuclease
HPMAHIPH_01922	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPMAHIPH_01923	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HPMAHIPH_01924	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPMAHIPH_01925	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPMAHIPH_01926	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HPMAHIPH_01927	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HPMAHIPH_01928	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPMAHIPH_01929	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPMAHIPH_01930	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPMAHIPH_01931	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPMAHIPH_01932	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HPMAHIPH_01933	1.91e-297	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_01934	4.97e-67	-	2.7.1.194	-	G	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_01935	1.87e-53	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_01936	4.67e-280	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HPMAHIPH_01937	1.16e-128	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HPMAHIPH_01938	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPMAHIPH_01939	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HPMAHIPH_01940	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HPMAHIPH_01941	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HPMAHIPH_01942	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPMAHIPH_01943	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HPMAHIPH_01944	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPMAHIPH_01945	4.41e-59	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HPMAHIPH_01946	5.61e-27	-	-	-	S	-	-	-	ABC-2 family transporter protein
HPMAHIPH_01947	3.49e-66	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_01954	1.67e-221	-	-	-	S	-	-	-	AAA-like domain
HPMAHIPH_01957	2.45e-20	-	-	-	S	-	-	-	maturation of SSU-rRNA
HPMAHIPH_01958	2.85e-47	yddH	-	-	M	-	-	-	Lysozyme-like
HPMAHIPH_01964	2.39e-71	-	-	-	S	ko:K12063	-	ko00000,ko02044	helicase activity
HPMAHIPH_01967	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HPMAHIPH_01968	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPMAHIPH_01969	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPMAHIPH_01970	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPMAHIPH_01971	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HPMAHIPH_01972	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPMAHIPH_01973	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HPMAHIPH_01974	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HPMAHIPH_01976	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HPMAHIPH_01977	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HPMAHIPH_01978	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPMAHIPH_01979	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPMAHIPH_01980	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HPMAHIPH_01981	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HPMAHIPH_01982	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HPMAHIPH_01983	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HPMAHIPH_01984	1.85e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPMAHIPH_01985	4.47e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HPMAHIPH_01986	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HPMAHIPH_01987	1.38e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPMAHIPH_01988	1.72e-242	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPMAHIPH_01989	1.51e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HPMAHIPH_01990	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HPMAHIPH_01991	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_01992	4.3e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_01993	5.58e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_01994	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HPMAHIPH_01995	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HPMAHIPH_01996	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPMAHIPH_01997	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPMAHIPH_01998	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPMAHIPH_01999	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPMAHIPH_02000	1.84e-189	-	-	-	-	-	-	-	-
HPMAHIPH_02001	4.58e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HPMAHIPH_02002	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HPMAHIPH_02003	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HPMAHIPH_02004	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HPMAHIPH_02005	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HPMAHIPH_02006	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPMAHIPH_02007	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPMAHIPH_02008	4.01e-36	-	-	-	-	-	-	-	-
HPMAHIPH_02009	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HPMAHIPH_02010	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPMAHIPH_02011	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HPMAHIPH_02012	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HPMAHIPH_02013	2.66e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPMAHIPH_02014	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPMAHIPH_02015	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPMAHIPH_02016	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HPMAHIPH_02017	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HPMAHIPH_02018	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HPMAHIPH_02019	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HPMAHIPH_02020	8.69e-179	-	-	-	-	-	-	-	-
HPMAHIPH_02021	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HPMAHIPH_02022	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPMAHIPH_02023	3.16e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HPMAHIPH_02024	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPMAHIPH_02025	1.13e-188	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HPMAHIPH_02026	5.3e-49	-	-	-	-	-	-	-	-
HPMAHIPH_02027	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
HPMAHIPH_02028	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HPMAHIPH_02029	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HPMAHIPH_02030	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HPMAHIPH_02031	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPMAHIPH_02032	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HPMAHIPH_02033	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPMAHIPH_02034	2.66e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPMAHIPH_02035	6.64e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HPMAHIPH_02036	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HPMAHIPH_02037	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPMAHIPH_02038	5.43e-91	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HPMAHIPH_02039	6.46e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HPMAHIPH_02040	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HPMAHIPH_02041	4.65e-229	-	-	-	-	-	-	-	-
HPMAHIPH_02042	5.59e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HPMAHIPH_02043	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HPMAHIPH_02044	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMAHIPH_02045	1.23e-262	-	-	-	-	-	-	-	-
HPMAHIPH_02046	1.2e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPMAHIPH_02047	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPMAHIPH_02048	6.97e-209	-	-	-	GK	-	-	-	ROK family
HPMAHIPH_02049	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02050	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02051	2.06e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HPMAHIPH_02052	9.68e-34	-	-	-	-	-	-	-	-
HPMAHIPH_02053	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02054	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HPMAHIPH_02055	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMAHIPH_02056	9.73e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HPMAHIPH_02057	0.0	-	-	-	L	-	-	-	DNA helicase
HPMAHIPH_02058	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HPMAHIPH_02059	2.99e-150	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02060	5.09e-141	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02061	1.89e-150	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02062	1.11e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02063	2.88e-307	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HPMAHIPH_02064	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPMAHIPH_02067	6.54e-168	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HPMAHIPH_02068	6.82e-170	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HPMAHIPH_02069	2.27e-289	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HPMAHIPH_02070	1.9e-25	plnA	-	-	-	-	-	-	-
HPMAHIPH_02071	1.22e-36	-	-	-	-	-	-	-	-
HPMAHIPH_02072	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
HPMAHIPH_02073	1.87e-289	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPMAHIPH_02075	4.08e-39	-	-	-	-	-	-	-	-
HPMAHIPH_02076	8.53e-34	plnJ	-	-	-	-	-	-	-
HPMAHIPH_02077	3.29e-32	plnK	-	-	-	-	-	-	-
HPMAHIPH_02078	9.76e-153	-	-	-	-	-	-	-	-
HPMAHIPH_02079	6.24e-25	plnR	-	-	-	-	-	-	-
HPMAHIPH_02080	1.15e-43	-	-	-	-	-	-	-	-
HPMAHIPH_02082	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPMAHIPH_02083	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HPMAHIPH_02085	8.38e-192	-	-	-	S	-	-	-	hydrolase
HPMAHIPH_02086	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02087	4.15e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_02088	1.95e-255	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HPMAHIPH_02089	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPMAHIPH_02091	3.27e-81	-	-	-	-	-	-	-	-
HPMAHIPH_02092	8.72e-24	-	-	-	-	-	-	-	-
HPMAHIPH_02095	6.97e-45	-	-	-	-	-	-	-	-
HPMAHIPH_02096	2.45e-162	-	-	-	-	-	-	-	-
HPMAHIPH_02098	5.76e-53	-	-	-	-	-	-	-	-
HPMAHIPH_02099	5.96e-46	-	-	-	-	-	-	-	-
HPMAHIPH_02101	1.17e-76	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HPMAHIPH_02102	0.0	-	-	-	M	-	-	-	domain protein
HPMAHIPH_02103	4.32e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_02104	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HPMAHIPH_02105	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPMAHIPH_02106	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HPMAHIPH_02107	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02108	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPMAHIPH_02109	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HPMAHIPH_02110	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_02111	3.66e-224	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HPMAHIPH_02112	4.02e-102	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPMAHIPH_02113	1.52e-103	-	-	-	-	-	-	-	-
HPMAHIPH_02114	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HPMAHIPH_02115	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HPMAHIPH_02116	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HPMAHIPH_02117	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HPMAHIPH_02118	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HPMAHIPH_02119	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPMAHIPH_02120	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HPMAHIPH_02121	8.95e-60	-	-	-	-	-	-	-	-
HPMAHIPH_02122	6.6e-229	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HPMAHIPH_02123	1.05e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HPMAHIPH_02124	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HPMAHIPH_02125	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HPMAHIPH_02126	3.93e-59	-	-	-	-	-	-	-	-
HPMAHIPH_02127	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPMAHIPH_02128	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HPMAHIPH_02129	1.29e-279	-	-	-	-	-	-	-	-
HPMAHIPH_02130	1.85e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HPMAHIPH_02131	9.36e-186	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPMAHIPH_02132	4.45e-116	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_02133	1.13e-157	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPMAHIPH_02134	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HPMAHIPH_02135	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
HPMAHIPH_02136	1.74e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPMAHIPH_02137	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HPMAHIPH_02138	6.4e-54	-	-	-	-	-	-	-	-
HPMAHIPH_02139	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HPMAHIPH_02140	7.28e-42	-	-	-	-	-	-	-	-
HPMAHIPH_02141	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HPMAHIPH_02142	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HPMAHIPH_02144	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HPMAHIPH_02145	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HPMAHIPH_02146	1.08e-243	-	-	-	-	-	-	-	-
HPMAHIPH_02147	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02148	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HPMAHIPH_02149	2.06e-30	-	-	-	-	-	-	-	-
HPMAHIPH_02150	3.04e-117	-	-	-	K	-	-	-	acetyltransferase
HPMAHIPH_02151	1.88e-111	-	-	-	K	-	-	-	GNAT family
HPMAHIPH_02152	8.08e-110	-	-	-	S	-	-	-	ASCH
HPMAHIPH_02153	4.3e-124	-	-	-	K	-	-	-	Cupin domain
HPMAHIPH_02154	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPMAHIPH_02155	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02156	7.92e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02157	4.36e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02158	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HPMAHIPH_02159	1.04e-35	-	-	-	-	-	-	-	-
HPMAHIPH_02161	6.01e-51	-	-	-	-	-	-	-	-
HPMAHIPH_02162	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HPMAHIPH_02163	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02164	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HPMAHIPH_02165	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPMAHIPH_02166	2.89e-75	-	-	-	-	-	-	-	-
HPMAHIPH_02167	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HPMAHIPH_02168	2.8e-169	-	-	-	-	-	-	-	-
HPMAHIPH_02169	4.29e-227	-	-	-	-	-	-	-	-
HPMAHIPH_02170	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HPMAHIPH_02171	1.43e-82	-	-	-	M	-	-	-	LysM domain protein
HPMAHIPH_02172	7.98e-80	-	-	-	M	-	-	-	Lysin motif
HPMAHIPH_02173	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02174	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02175	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_02176	1.76e-293	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HPMAHIPH_02177	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HPMAHIPH_02178	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HPMAHIPH_02179	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HPMAHIPH_02180	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HPMAHIPH_02181	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HPMAHIPH_02182	1.49e-63	-	-	-	-	-	-	-	-
HPMAHIPH_02183	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HPMAHIPH_02184	1.02e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HPMAHIPH_02185	2.87e-56	-	-	-	-	-	-	-	-
HPMAHIPH_02186	3.92e-74	-	-	-	-	-	-	-	-
HPMAHIPH_02187	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02188	1.13e-166	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPMAHIPH_02189	2.42e-65	-	-	-	-	-	-	-	-
HPMAHIPH_02190	3.28e-166	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HPMAHIPH_02191	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HPMAHIPH_02192	8.98e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_02193	2.34e-154	ydiC	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_02194	5.98e-103	ydiC	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_02195	1.55e-55	-	-	-	-	-	-	-	-
HPMAHIPH_02196	2.41e-56	-	-	-	-	-	-	-	-
HPMAHIPH_02197	1.15e-152	-	-	-	-	-	-	-	-
HPMAHIPH_02198	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HPMAHIPH_02199	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_02200	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02201	9.53e-93	-	-	-	-	-	-	-	-
HPMAHIPH_02202	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HPMAHIPH_02203	6.12e-184	-	-	-	-	-	-	-	-
HPMAHIPH_02204	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HPMAHIPH_02205	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_02206	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HPMAHIPH_02207	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HPMAHIPH_02208	2.21e-56	-	-	-	-	-	-	-	-
HPMAHIPH_02209	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HPMAHIPH_02210	1.41e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HPMAHIPH_02211	7.85e-202	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HPMAHIPH_02212	6.2e-210	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HPMAHIPH_02213	2.35e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HPMAHIPH_02214	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HPMAHIPH_02215	1.93e-243	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HPMAHIPH_02216	1.65e-125	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HPMAHIPH_02217	2.49e-25	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HPMAHIPH_02218	2.92e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HPMAHIPH_02219	5.16e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HPMAHIPH_02220	9.23e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HPMAHIPH_02221	6.14e-53	-	-	-	-	-	-	-	-
HPMAHIPH_02222	1.66e-290	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02223	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HPMAHIPH_02224	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HPMAHIPH_02225	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HPMAHIPH_02226	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HPMAHIPH_02227	2.98e-90	-	-	-	-	-	-	-	-
HPMAHIPH_02228	3.51e-125	-	-	-	-	-	-	-	-
HPMAHIPH_02229	2.23e-62	-	-	-	-	-	-	-	-
HPMAHIPH_02230	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HPMAHIPH_02231	2.23e-107	-	-	-	-	-	-	-	-
HPMAHIPH_02232	4.33e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HPMAHIPH_02233	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02234	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HPMAHIPH_02235	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02236	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HPMAHIPH_02237	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_02238	9.17e-282	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HPMAHIPH_02239	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HPMAHIPH_02240	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPMAHIPH_02241	1.2e-91	-	-	-	-	-	-	-	-
HPMAHIPH_02242	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPMAHIPH_02243	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HPMAHIPH_02244	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HPMAHIPH_02245	8.25e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02246	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HPMAHIPH_02247	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HPMAHIPH_02248	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HPMAHIPH_02249	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPMAHIPH_02250	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPMAHIPH_02251	3.81e-18	-	-	-	-	-	-	-	-
HPMAHIPH_02252	5.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPMAHIPH_02253	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HPMAHIPH_02254	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HPMAHIPH_02255	6.33e-46	-	-	-	-	-	-	-	-
HPMAHIPH_02257	1.89e-112	-	-	-	S	-	-	-	Prophage endopeptidase tail
HPMAHIPH_02258	4.86e-110	-	-	-	S	-	-	-	Phage tail protein
HPMAHIPH_02259	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HPMAHIPH_02260	2.11e-06	-	-	-	-	-	-	-	-
HPMAHIPH_02262	3.4e-89	-	-	-	S	-	-	-	Phage tail tube protein
HPMAHIPH_02264	1.26e-48	-	-	-	-	-	-	-	-
HPMAHIPH_02267	2.58e-203	-	-	-	S	-	-	-	Phage capsid family
HPMAHIPH_02268	1.06e-101	-	-	-	S	-	-	-	Clp protease
HPMAHIPH_02269	1.04e-195	-	-	-	S	-	-	-	Phage portal protein
HPMAHIPH_02270	1.8e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HPMAHIPH_02271	0.0	-	-	-	S	-	-	-	Phage Terminase
HPMAHIPH_02272	6.91e-66	-	-	-	L	-	-	-	Phage terminase, small subunit
HPMAHIPH_02274	6.97e-90	-	-	-	L	-	-	-	HNH nucleases
HPMAHIPH_02279	8.86e-26	-	-	-	-	-	-	-	-
HPMAHIPH_02281	1.02e-40	-	-	-	-	-	-	-	-
HPMAHIPH_02283	5.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02284	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HPMAHIPH_02285	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HPMAHIPH_02286	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HPMAHIPH_02287	0.0	ycaM	-	-	E	-	-	-	amino acid
HPMAHIPH_02288	2.89e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HPMAHIPH_02289	4.3e-44	-	-	-	-	-	-	-	-
HPMAHIPH_02290	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HPMAHIPH_02291	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HPMAHIPH_02292	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HPMAHIPH_02293	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HPMAHIPH_02294	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HPMAHIPH_02295	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPMAHIPH_02296	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_02297	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPMAHIPH_02298	5.06e-196	-	-	-	S	-	-	-	hydrolase
HPMAHIPH_02299	7.63e-107	-	-	-	-	-	-	-	-
HPMAHIPH_02300	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HPMAHIPH_02301	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HPMAHIPH_02302	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HPMAHIPH_02303	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02304	2.73e-73	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HPMAHIPH_02305	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02306	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02307	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HPMAHIPH_02308	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HPMAHIPH_02309	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_02310	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02311	1.15e-190	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPMAHIPH_02312	3.34e-101	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPMAHIPH_02313	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HPMAHIPH_02314	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HPMAHIPH_02315	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HPMAHIPH_02316	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HPMAHIPH_02317	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HPMAHIPH_02318	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HPMAHIPH_02319	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HPMAHIPH_02320	7.16e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPMAHIPH_02321	2.38e-37	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HPMAHIPH_02322	1.1e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HPMAHIPH_02323	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HPMAHIPH_02324	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HPMAHIPH_02326	1.21e-69	-	-	-	-	-	-	-	-
HPMAHIPH_02327	1.52e-151	-	-	-	-	-	-	-	-
HPMAHIPH_02328	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HPMAHIPH_02329	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HPMAHIPH_02330	4.79e-13	-	-	-	-	-	-	-	-
HPMAHIPH_02331	1.4e-65	-	-	-	-	-	-	-	-
HPMAHIPH_02332	1.76e-114	-	-	-	-	-	-	-	-
HPMAHIPH_02333	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HPMAHIPH_02334	1.08e-47	-	-	-	-	-	-	-	-
HPMAHIPH_02335	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HPMAHIPH_02336	5.66e-189	-	-	-	-	-	-	-	-
HPMAHIPH_02337	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02338	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HPMAHIPH_02339	4.76e-56	-	-	-	-	-	-	-	-
HPMAHIPH_02340	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPMAHIPH_02341	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02342	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HPMAHIPH_02343	2.4e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_02344	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HPMAHIPH_02345	1.68e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HPMAHIPH_02346	1.65e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HPMAHIPH_02347	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HPMAHIPH_02348	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HPMAHIPH_02349	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPMAHIPH_02350	3.35e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPMAHIPH_02351	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HPMAHIPH_02352	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPMAHIPH_02353	2.82e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPMAHIPH_02354	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPMAHIPH_02355	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPMAHIPH_02356	1.04e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HPMAHIPH_02357	1.79e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPMAHIPH_02358	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HPMAHIPH_02359	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HPMAHIPH_02360	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
HPMAHIPH_02361	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HPMAHIPH_02362	1.85e-121	-	-	-	-	-	-	-	-
HPMAHIPH_02363	4.18e-198	-	-	-	T	-	-	-	EAL domain
HPMAHIPH_02364	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HPMAHIPH_02365	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HPMAHIPH_02366	4.41e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HPMAHIPH_02367	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HPMAHIPH_02368	1.01e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPMAHIPH_02369	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HPMAHIPH_02370	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPMAHIPH_02371	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HPMAHIPH_02372	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HPMAHIPH_02373	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPMAHIPH_02374	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPMAHIPH_02375	2.7e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPMAHIPH_02376	4.54e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HPMAHIPH_02377	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPMAHIPH_02378	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HPMAHIPH_02379	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HPMAHIPH_02380	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02381	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HPMAHIPH_02382	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HPMAHIPH_02383	3.59e-26	-	-	-	-	-	-	-	-
HPMAHIPH_02384	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPMAHIPH_02385	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HPMAHIPH_02386	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HPMAHIPH_02387	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPMAHIPH_02388	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HPMAHIPH_02389	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPMAHIPH_02390	8.13e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_02391	3.36e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_02392	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HPMAHIPH_02393	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HPMAHIPH_02394	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HPMAHIPH_02395	2.97e-76	-	-	-	-	-	-	-	-
HPMAHIPH_02396	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HPMAHIPH_02397	1.55e-79	-	-	-	-	-	-	-	-
HPMAHIPH_02398	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HPMAHIPH_02399	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HPMAHIPH_02400	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HPMAHIPH_02401	1.18e-176	-	-	-	-	-	-	-	-
HPMAHIPH_02402	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPMAHIPH_02403	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02404	2.25e-206	-	-	-	S	-	-	-	Putative esterase
HPMAHIPH_02405	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HPMAHIPH_02406	7.54e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMAHIPH_02407	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HPMAHIPH_02408	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HPMAHIPH_02411	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HPMAHIPH_02412	2.73e-24	-	-	-	-	-	-	-	-
HPMAHIPH_02413	9.75e-201	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HPMAHIPH_02414	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HPMAHIPH_02415	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HPMAHIPH_02416	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HPMAHIPH_02417	4.15e-78	-	-	-	-	-	-	-	-
HPMAHIPH_02418	4.05e-98	-	-	-	-	-	-	-	-
HPMAHIPH_02419	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HPMAHIPH_02420	1.57e-71	-	-	-	-	-	-	-	-
HPMAHIPH_02421	3.74e-60	-	-	-	-	-	-	-	-
HPMAHIPH_02422	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HPMAHIPH_02423	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HPMAHIPH_02424	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HPMAHIPH_02425	1.17e-88	-	-	-	-	-	-	-	-
HPMAHIPH_02426	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_02427	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPMAHIPH_02428	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HPMAHIPH_02429	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HPMAHIPH_02430	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HPMAHIPH_02431	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_02432	1.21e-128	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HPMAHIPH_02433	2.25e-59	-	-	-	-	-	-	-	-
HPMAHIPH_02434	9.96e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HPMAHIPH_02435	1.03e-65	-	-	-	-	-	-	-	-
HPMAHIPH_02436	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HPMAHIPH_02437	1.15e-282	-	-	-	S	-	-	-	associated with various cellular activities
HPMAHIPH_02438	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_02439	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HPMAHIPH_02440	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HPMAHIPH_02441	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HPMAHIPH_02442	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HPMAHIPH_02443	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_02444	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPMAHIPH_02445	2.49e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HPMAHIPH_02446	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPMAHIPH_02447	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HPMAHIPH_02448	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMAHIPH_02449	1.31e-128	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HPMAHIPH_02450	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HPMAHIPH_02451	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_02452	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HPMAHIPH_02453	5.14e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPMAHIPH_02454	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPMAHIPH_02455	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMAHIPH_02456	1.11e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HPMAHIPH_02457	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMAHIPH_02458	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HPMAHIPH_02459	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HPMAHIPH_02460	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_02461	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HPMAHIPH_02462	4.07e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HPMAHIPH_02463	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPMAHIPH_02464	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMAHIPH_02465	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HPMAHIPH_02466	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPMAHIPH_02467	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HPMAHIPH_02468	4.02e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_02469	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPMAHIPH_02470	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPMAHIPH_02471	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HPMAHIPH_02472	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HPMAHIPH_02473	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HPMAHIPH_02474	2.62e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_02475	2.09e-83	-	-	-	-	-	-	-	-
HPMAHIPH_02476	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HPMAHIPH_02477	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HPMAHIPH_02478	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02479	1.25e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPMAHIPH_02480	1.76e-204	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HPMAHIPH_02481	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HPMAHIPH_02482	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02483	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_02484	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HPMAHIPH_02485	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02486	4.72e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HPMAHIPH_02487	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02488	1.17e-96	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02489	1.48e-103	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPMAHIPH_02490	1.73e-178	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HPMAHIPH_02491	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_02492	8.71e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPMAHIPH_02493	3.25e-252	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HPMAHIPH_02494	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02495	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02496	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HPMAHIPH_02497	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HPMAHIPH_02498	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HPMAHIPH_02499	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HPMAHIPH_02500	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HPMAHIPH_02501	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HPMAHIPH_02503	8.95e-225	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPMAHIPH_02504	2.58e-186	yxeH	-	-	S	-	-	-	hydrolase
HPMAHIPH_02505	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPMAHIPH_02506	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPMAHIPH_02507	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HPMAHIPH_02508	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HPMAHIPH_02509	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02510	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02511	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HPMAHIPH_02512	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HPMAHIPH_02513	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HPMAHIPH_02514	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02515	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02516	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HPMAHIPH_02517	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HPMAHIPH_02518	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HPMAHIPH_02519	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HPMAHIPH_02520	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HPMAHIPH_02521	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HPMAHIPH_02522	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HPMAHIPH_02523	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPMAHIPH_02524	1.4e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HPMAHIPH_02525	5.02e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPMAHIPH_02526	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HPMAHIPH_02527	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HPMAHIPH_02528	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HPMAHIPH_02529	1.06e-16	-	-	-	-	-	-	-	-
HPMAHIPH_02530	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HPMAHIPH_02531	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HPMAHIPH_02532	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HPMAHIPH_02533	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HPMAHIPH_02534	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HPMAHIPH_02535	9.62e-19	-	-	-	-	-	-	-	-
HPMAHIPH_02536	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HPMAHIPH_02537	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HPMAHIPH_02539	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPMAHIPH_02540	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_02541	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02542	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_02543	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HPMAHIPH_02544	1.45e-162	-	-	-	S	-	-	-	Membrane
HPMAHIPH_02545	3.76e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HPMAHIPH_02546	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HPMAHIPH_02547	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HPMAHIPH_02548	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HPMAHIPH_02549	2.67e-310	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HPMAHIPH_02550	8.35e-230	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMAHIPH_02551	1.28e-180	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HPMAHIPH_02552	3.05e-104	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPMAHIPH_02553	2.47e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02554	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HPMAHIPH_02556	4.32e-174	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HPMAHIPH_02557	0.0	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPMAHIPH_02558	1.01e-252	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HPMAHIPH_02559	2.4e-258	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HPMAHIPH_02560	3.39e-226	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HPMAHIPH_02561	6.56e-252	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HPMAHIPH_02562	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPMAHIPH_02563	1.87e-246	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HPMAHIPH_02564	7.45e-108	-	-	-	S	-	-	-	Haem-degrading
HPMAHIPH_02565	1.6e-220	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HPMAHIPH_02566	1.44e-228	-	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HPMAHIPH_02567	2.88e-153	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HPMAHIPH_02568	5.31e-82	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HPMAHIPH_02569	5.39e-228	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HPMAHIPH_02570	1.88e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HPMAHIPH_02571	4.71e-119	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HPMAHIPH_02572	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HPMAHIPH_02573	3.5e-184	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HPMAHIPH_02574	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02575	2.43e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPMAHIPH_02576	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
HPMAHIPH_02577	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HPMAHIPH_02578	1.54e-247	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02579	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMAHIPH_02580	1.09e-275	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HPMAHIPH_02581	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HPMAHIPH_02582	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HPMAHIPH_02583	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HPMAHIPH_02584	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
HPMAHIPH_02585	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HPMAHIPH_02586	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
HPMAHIPH_02587	6.47e-213	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_02588	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HPMAHIPH_02589	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMAHIPH_02590	9.5e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMAHIPH_02591	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HPMAHIPH_02592	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02593	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HPMAHIPH_02594	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HPMAHIPH_02595	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HPMAHIPH_02596	2.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HPMAHIPH_02597	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HPMAHIPH_02598	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HPMAHIPH_02599	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HPMAHIPH_02600	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HPMAHIPH_02601	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HPMAHIPH_02602	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPMAHIPH_02603	3.87e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPMAHIPH_02604	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HPMAHIPH_02605	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HPMAHIPH_02606	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HPMAHIPH_02607	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HPMAHIPH_02608	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HPMAHIPH_02609	3.79e-181	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HPMAHIPH_02610	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_02611	4.02e-203	degV1	-	-	S	-	-	-	DegV family
HPMAHIPH_02612	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HPMAHIPH_02613	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HPMAHIPH_02615	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPMAHIPH_02616	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_02618	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HPMAHIPH_02619	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HPMAHIPH_02620	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPMAHIPH_02621	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPMAHIPH_02622	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HPMAHIPH_02623	1.53e-304	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HPMAHIPH_02624	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_02625	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPMAHIPH_02626	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPMAHIPH_02627	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPMAHIPH_02628	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPMAHIPH_02629	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HPMAHIPH_02630	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPMAHIPH_02631	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPMAHIPH_02632	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPMAHIPH_02633	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HPMAHIPH_02634	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPMAHIPH_02635	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPMAHIPH_02636	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HPMAHIPH_02637	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HPMAHIPH_02638	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HPMAHIPH_02639	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_02640	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPMAHIPH_02641	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPMAHIPH_02643	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HPMAHIPH_02645	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPMAHIPH_02646	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPMAHIPH_02647	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HPMAHIPH_02648	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HPMAHIPH_02649	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPMAHIPH_02650	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HPMAHIPH_02651	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HPMAHIPH_02652	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HPMAHIPH_02653	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HPMAHIPH_02654	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HPMAHIPH_02655	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HPMAHIPH_02656	2.54e-50	-	-	-	-	-	-	-	-
HPMAHIPH_02658	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HPMAHIPH_02659	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HPMAHIPH_02660	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
HPMAHIPH_02661	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HPMAHIPH_02662	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HPMAHIPH_02663	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HPMAHIPH_02664	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPMAHIPH_02665	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_02666	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HPMAHIPH_02667	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HPMAHIPH_02668	1.35e-156	pnb	-	-	C	-	-	-	nitroreductase
HPMAHIPH_02669	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HPMAHIPH_02670	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HPMAHIPH_02671	1.16e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HPMAHIPH_02672	0.0	-	-	-	C	-	-	-	FMN_bind
HPMAHIPH_02673	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HPMAHIPH_02674	1.46e-204	-	-	-	K	-	-	-	LysR family
HPMAHIPH_02675	1.69e-93	-	-	-	C	-	-	-	FMN binding
HPMAHIPH_02676	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPMAHIPH_02677	1.66e-210	-	-	-	S	-	-	-	KR domain
HPMAHIPH_02678	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HPMAHIPH_02679	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HPMAHIPH_02680	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HPMAHIPH_02681	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HPMAHIPH_02682	1.54e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPMAHIPH_02683	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HPMAHIPH_02684	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HPMAHIPH_02685	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HPMAHIPH_02686	1.65e-106	-	-	-	S	-	-	-	ASCH
HPMAHIPH_02687	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HPMAHIPH_02688	1.67e-220	-	-	-	K	-	-	-	WYL domain
HPMAHIPH_02689	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPMAHIPH_02690	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HPMAHIPH_02691	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HPMAHIPH_02692	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
HPMAHIPH_02693	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_02694	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HPMAHIPH_02695	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HPMAHIPH_02696	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HPMAHIPH_02697	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_02698	2e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HPMAHIPH_02699	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HPMAHIPH_02700	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HPMAHIPH_02701	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPMAHIPH_02702	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPMAHIPH_02703	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPMAHIPH_02704	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPMAHIPH_02705	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPMAHIPH_02706	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPMAHIPH_02707	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HPMAHIPH_02708	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPMAHIPH_02709	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HPMAHIPH_02710	8.33e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HPMAHIPH_02711	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HPMAHIPH_02712	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HPMAHIPH_02713	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HPMAHIPH_02714	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HPMAHIPH_02715	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPMAHIPH_02716	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02717	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HPMAHIPH_02718	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HPMAHIPH_02719	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HPMAHIPH_02720	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPMAHIPH_02721	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HPMAHIPH_02722	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HPMAHIPH_02723	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_02724	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HPMAHIPH_02725	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HPMAHIPH_02726	1.34e-52	-	-	-	-	-	-	-	-
HPMAHIPH_02727	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HPMAHIPH_02728	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HPMAHIPH_02729	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HPMAHIPH_02730	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HPMAHIPH_02731	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HPMAHIPH_02732	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HPMAHIPH_02733	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HPMAHIPH_02734	4.84e-289	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HPMAHIPH_02735	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_02736	6.4e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HPMAHIPH_02737	2.82e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HPMAHIPH_02738	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HPMAHIPH_02739	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPMAHIPH_02740	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HPMAHIPH_02741	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPMAHIPH_02742	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HPMAHIPH_02743	6.29e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPMAHIPH_02744	4.5e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HPMAHIPH_02745	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPMAHIPH_02746	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPMAHIPH_02747	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HPMAHIPH_02748	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HPMAHIPH_02749	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HPMAHIPH_02750	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HPMAHIPH_02751	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HPMAHIPH_02752	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HPMAHIPH_02753	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HPMAHIPH_02754	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02755	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02756	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HPMAHIPH_02757	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HPMAHIPH_02758	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HPMAHIPH_02759	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HPMAHIPH_02760	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HPMAHIPH_02761	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPMAHIPH_02762	2.21e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HPMAHIPH_02763	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPMAHIPH_02764	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HPMAHIPH_02765	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HPMAHIPH_02766	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPMAHIPH_02767	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPMAHIPH_02768	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HPMAHIPH_02769	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_02770	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HPMAHIPH_02771	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPMAHIPH_02772	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HPMAHIPH_02773	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HPMAHIPH_02774	1.66e-40	-	-	-	FG	-	-	-	HIT domain
HPMAHIPH_02775	3.23e-73	-	-	-	FG	-	-	-	HIT domain
HPMAHIPH_02776	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPMAHIPH_02777	4.29e-101	-	-	-	-	-	-	-	-
HPMAHIPH_02778	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPMAHIPH_02779	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02780	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMAHIPH_02781	2.03e-84	-	-	-	-	-	-	-	-
HPMAHIPH_02782	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HPMAHIPH_02783	2.86e-72	-	-	-	-	-	-	-	-
HPMAHIPH_02784	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_02785	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPMAHIPH_02786	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HPMAHIPH_02787	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02788	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HPMAHIPH_02789	7.48e-236	-	-	-	GM	-	-	-	Male sterility protein
HPMAHIPH_02790	4.4e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_02791	4.61e-101	-	-	-	M	-	-	-	LysM domain
HPMAHIPH_02792	3.03e-130	-	-	-	M	-	-	-	Lysin motif
HPMAHIPH_02793	4.02e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HPMAHIPH_02794	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HPMAHIPH_02795	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HPMAHIPH_02796	3.57e-120	-	-	-	-	-	-	-	-
HPMAHIPH_02797	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HPMAHIPH_02798	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HPMAHIPH_02799	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMAHIPH_02800	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HPMAHIPH_02801	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HPMAHIPH_02802	5.26e-96	-	-	-	-	-	-	-	-
HPMAHIPH_02803	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_02804	5.37e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HPMAHIPH_02805	2.51e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02806	1.6e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HPMAHIPH_02807	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
HPMAHIPH_02808	2.06e-78	-	-	-	I	-	-	-	sulfurtransferase activity
HPMAHIPH_02809	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HPMAHIPH_02810	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02811	2.31e-277	-	-	-	-	-	-	-	-
HPMAHIPH_02812	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02813	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02814	1.65e-21	-	-	-	-	-	-	-	-
HPMAHIPH_02815	1.87e-289	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HPMAHIPH_02816	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HPMAHIPH_02818	6.6e-91	-	-	-	-	-	-	-	-
HPMAHIPH_02819	8.63e-186	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_02820	0.0	-	-	-	E	-	-	-	Amino Acid
HPMAHIPH_02821	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HPMAHIPH_02822	1.71e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HPMAHIPH_02823	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02824	1.59e-268	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPMAHIPH_02825	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_02826	2e-73	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HPMAHIPH_02827	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HPMAHIPH_02828	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HPMAHIPH_02829	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HPMAHIPH_02830	1.59e-137	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02831	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HPMAHIPH_02832	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_02834	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPMAHIPH_02835	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPMAHIPH_02836	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPMAHIPH_02837	2.82e-110	-	-	-	-	-	-	-	-
HPMAHIPH_02838	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
HPMAHIPH_02839	3.98e-49	-	-	-	-	-	-	-	-
HPMAHIPH_02840	2.81e-64	-	-	-	-	-	-	-	-
HPMAHIPH_02841	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HPMAHIPH_02842	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HPMAHIPH_02843	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_02844	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02845	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HPMAHIPH_02846	5.85e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPMAHIPH_02847	1.2e-181	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HPMAHIPH_02848	4.83e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HPMAHIPH_02849	2.14e-98	-	-	-	C	-	-	-	Flavodoxin
HPMAHIPH_02850	2.78e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HPMAHIPH_02851	1.43e-114	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HPMAHIPH_02852	7.8e-113	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02853	2.11e-132	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HPMAHIPH_02854	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_02856	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
HPMAHIPH_02857	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HPMAHIPH_02858	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMAHIPH_02859	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
HPMAHIPH_02860	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HPMAHIPH_02861	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HPMAHIPH_02862	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMAHIPH_02863	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HPMAHIPH_02864	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HPMAHIPH_02865	1.19e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HPMAHIPH_02866	1.12e-105	-	-	-	-	-	-	-	-
HPMAHIPH_02867	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HPMAHIPH_02868	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HPMAHIPH_02869	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HPMAHIPH_02870	4.96e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
HPMAHIPH_02872	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02873	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HPMAHIPH_02874	9.09e-314	-	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_02877	1.58e-230	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HPMAHIPH_02878	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HPMAHIPH_02879	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_02880	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HPMAHIPH_02881	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPMAHIPH_02882	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HPMAHIPH_02883	6.26e-289	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_02884	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HPMAHIPH_02885	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HPMAHIPH_02886	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HPMAHIPH_02887	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HPMAHIPH_02888	1.15e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HPMAHIPH_02889	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMAHIPH_02890	2.51e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HPMAHIPH_02891	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HPMAHIPH_02892	3.02e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPMAHIPH_02893	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HPMAHIPH_02894	0.0	-	-	-	-	-	-	-	-
HPMAHIPH_02895	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HPMAHIPH_02896	5.02e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPMAHIPH_02897	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HPMAHIPH_02898	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HPMAHIPH_02899	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPMAHIPH_02900	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HPMAHIPH_02901	1.56e-108	-	-	-	-	-	-	-	-
HPMAHIPH_02902	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPMAHIPH_02903	5.32e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMAHIPH_02904	2.09e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPMAHIPH_02905	3.7e-30	-	-	-	-	-	-	-	-
HPMAHIPH_02906	1.84e-134	-	-	-	-	-	-	-	-
HPMAHIPH_02907	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HPMAHIPH_02908	4.15e-312	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HPMAHIPH_02909	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPMAHIPH_02910	7.68e-172	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMAHIPH_02911	8.42e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HPMAHIPH_02912	1.82e-253	cps3I	-	-	G	-	-	-	Acyltransferase family
HPMAHIPH_02913	1.79e-35	cps3H	-	-	-	-	-	-	-
HPMAHIPH_02914	2.85e-204	cps3H	-	-	-	-	-	-	-
HPMAHIPH_02915	2.03e-208	cps3F	-	-	-	-	-	-	-
HPMAHIPH_02916	6.87e-144	cps3E	-	-	-	-	-	-	-
HPMAHIPH_02917	3.93e-260	cps3D	-	-	-	-	-	-	-
HPMAHIPH_02918	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HPMAHIPH_02919	5.21e-226	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPMAHIPH_02920	1.54e-219	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HPMAHIPH_02921	1.55e-34	-	-	-	S	-	-	-	Barstar (barnase inhibitor)
HPMAHIPH_02922	8.72e-73	-	-	-	S	-	-	-	Immunity protein 63
HPMAHIPH_02924	1.63e-145	-	-	-	-	-	-	-	-
HPMAHIPH_02926	4.82e-56	-	-	-	S	-	-	-	ankyrin repeats
HPMAHIPH_02928	3.34e-191	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HPMAHIPH_02929	0.000143	-	-	-	U	ko:K15125	ko05133,map05133	ko00000,ko00001,ko00536	Large exoproteins involved in heme utilization or adhesion
HPMAHIPH_02930	4.25e-143	-	-	-	-	-	-	-	-
HPMAHIPH_02931	9.31e-174	-	-	-	-	-	-	-	-
HPMAHIPH_02932	9.17e-41	-	-	-	-	-	-	-	-
HPMAHIPH_02933	3.07e-48	-	-	-	-	-	-	-	-
HPMAHIPH_02934	4.52e-153	-	-	-	-	-	-	-	-
HPMAHIPH_02936	3.23e-58	-	-	-	-	-	-	-	-
HPMAHIPH_02937	1.51e-119	-	-	-	M	ko:K21493	-	ko00000,ko01000,ko02048	self proteolysis
HPMAHIPH_02938	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HPMAHIPH_02939	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPMAHIPH_02940	5.51e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HPMAHIPH_02941	4.21e-158	-	-	-	S	-	-	-	YjbR
HPMAHIPH_02943	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HPMAHIPH_02944	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HPMAHIPH_02945	1.86e-175	-	-	-	M	-	-	-	domain protein
HPMAHIPH_02946	1e-28	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HPMAHIPH_02947	2.34e-105	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HPMAHIPH_02948	5.71e-57	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HPMAHIPH_02949	1.26e-168	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMAHIPH_02950	2.55e-219	-	-	-	-	-	-	-	-
HPMAHIPH_02951	1.54e-159	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HPMAHIPH_02952	1.47e-166	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HPMAHIPH_02953	8.38e-160	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HPMAHIPH_02954	1.33e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HPMAHIPH_02955	8.15e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HPMAHIPH_02956	6.79e-163	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HPMAHIPH_02957	2.18e-168	epsB	-	-	M	-	-	-	biosynthesis protein
HPMAHIPH_02958	3.69e-130	-	-	-	L	-	-	-	Integrase
HPMAHIPH_02959	2.94e-237	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPMAHIPH_02960	2.89e-129	-	-	-	M	-	-	-	Parallel beta-helix repeats
HPMAHIPH_02961	1.33e-82	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HPMAHIPH_02962	4.99e-215	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HPMAHIPH_02963	6.89e-68	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HPMAHIPH_02964	1.4e-62	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPMAHIPH_02965	2e-117	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HPMAHIPH_02966	5.78e-100	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HPMAHIPH_02967	1.43e-28	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HPMAHIPH_02968	7.12e-09	-	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_02969	2.23e-10	cap5B	-	-	D	-	-	-	NUBPL iron-transfer P-loop NTPase
HPMAHIPH_02971	6.08e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HPMAHIPH_02972	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HPMAHIPH_02973	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HPMAHIPH_02974	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPMAHIPH_02975	1.63e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HPMAHIPH_02976	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HPMAHIPH_02977	2.9e-139	-	-	-	-	-	-	-	-
HPMAHIPH_02978	7.62e-97	-	-	-	-	-	-	-	-
HPMAHIPH_02980	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_02981	3.25e-315	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02982	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HPMAHIPH_02984	9.46e-315	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HPMAHIPH_02985	1.59e-244	mocA	-	-	S	-	-	-	Oxidoreductase
HPMAHIPH_02986	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HPMAHIPH_02987	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HPMAHIPH_02988	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HPMAHIPH_02989	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HPMAHIPH_02990	3.35e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_02991	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPMAHIPH_02992	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HPMAHIPH_02993	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_02994	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPMAHIPH_02995	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HPMAHIPH_02996	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPMAHIPH_02997	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPMAHIPH_02998	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPMAHIPH_02999	7.78e-262	camS	-	-	S	-	-	-	sex pheromone
HPMAHIPH_03000	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPMAHIPH_03001	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HPMAHIPH_03002	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPMAHIPH_03003	2.67e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HPMAHIPH_03004	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPMAHIPH_03005	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HPMAHIPH_03006	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPMAHIPH_03007	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HPMAHIPH_03008	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPMAHIPH_03009	4.44e-207	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPMAHIPH_03010	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPMAHIPH_03011	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPMAHIPH_03012	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HPMAHIPH_03013	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HPMAHIPH_03014	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HPMAHIPH_03015	6.07e-33	-	-	-	-	-	-	-	-
HPMAHIPH_03016	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HPMAHIPH_03017	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HPMAHIPH_03018	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HPMAHIPH_03019	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HPMAHIPH_03020	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HPMAHIPH_03021	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HPMAHIPH_03022	1.24e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HPMAHIPH_03023	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HPMAHIPH_03024	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPMAHIPH_03025	6.03e-246	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HPMAHIPH_03026	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HPMAHIPH_03028	2.28e-59	-	-	-	K	-	-	-	sequence-specific DNA binding
HPMAHIPH_03029	1.4e-185	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HPMAHIPH_03030	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HPMAHIPH_03031	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HPMAHIPH_03032	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HPMAHIPH_03033	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPMAHIPH_03034	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HPMAHIPH_03035	1.68e-227	citR	-	-	K	-	-	-	sugar-binding domain protein
HPMAHIPH_03036	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HPMAHIPH_03037	7.56e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HPMAHIPH_03038	1.18e-66	-	-	-	-	-	-	-	-
HPMAHIPH_03039	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HPMAHIPH_03040	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HPMAHIPH_03041	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HPMAHIPH_03042	7.77e-197	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPMAHIPH_03043	1.55e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_03044	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HPMAHIPH_03045	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HPMAHIPH_03046	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HPMAHIPH_03047	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HPMAHIPH_03048	2.12e-252	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPMAHIPH_03049	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HPMAHIPH_03050	2.86e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPMAHIPH_03051	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPMAHIPH_03052	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HPMAHIPH_03053	7e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HPMAHIPH_03054	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HPMAHIPH_03055	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPMAHIPH_03056	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPMAHIPH_03057	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPMAHIPH_03058	3.47e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPMAHIPH_03059	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPMAHIPH_03060	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMAHIPH_03061	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HPMAHIPH_03062	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HPMAHIPH_03063	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HPMAHIPH_03064	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HPMAHIPH_03065	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPMAHIPH_03066	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HPMAHIPH_03067	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPMAHIPH_03068	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPMAHIPH_03069	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPMAHIPH_03070	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPMAHIPH_03071	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPMAHIPH_03072	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPMAHIPH_03073	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HPMAHIPH_03074	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HPMAHIPH_03075	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPMAHIPH_03076	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPMAHIPH_03077	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPMAHIPH_03078	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPMAHIPH_03079	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPMAHIPH_03080	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPMAHIPH_03081	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPMAHIPH_03082	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPMAHIPH_03083	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HPMAHIPH_03084	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPMAHIPH_03085	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPMAHIPH_03086	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPMAHIPH_03087	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPMAHIPH_03088	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPMAHIPH_03089	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPMAHIPH_03090	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HPMAHIPH_03091	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPMAHIPH_03092	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HPMAHIPH_03093	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPMAHIPH_03094	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPMAHIPH_03095	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPMAHIPH_03096	1e-147	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HPMAHIPH_03097	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPMAHIPH_03098	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPMAHIPH_03099	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_03100	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPMAHIPH_03101	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HPMAHIPH_03109	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPMAHIPH_03110	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HPMAHIPH_03111	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HPMAHIPH_03112	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HPMAHIPH_03113	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_03114	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_03115	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HPMAHIPH_03116	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPMAHIPH_03117	2.05e-153	-	-	-	I	-	-	-	phosphatase
HPMAHIPH_03118	3.33e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HPMAHIPH_03119	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPMAHIPH_03120	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HPMAHIPH_03121	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HPMAHIPH_03122	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HPMAHIPH_03123	1.36e-77	-	-	-	-	-	-	-	-
HPMAHIPH_03124	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HPMAHIPH_03125	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HPMAHIPH_03126	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HPMAHIPH_03127	1.46e-170	-	-	-	-	-	-	-	-
HPMAHIPH_03128	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HPMAHIPH_03129	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_03130	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HPMAHIPH_03131	4.08e-216	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HPMAHIPH_03132	4.4e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HPMAHIPH_03133	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HPMAHIPH_03134	2.13e-295	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HPMAHIPH_03135	5.97e-210	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HPMAHIPH_03136	5.54e-244	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPMAHIPH_03137	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HPMAHIPH_03138	9.2e-62	-	-	-	-	-	-	-	-
HPMAHIPH_03139	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPMAHIPH_03141	3.07e-18	-	-	-	V	-	-	-	HNH nucleases
HPMAHIPH_03142	9.36e-36	-	-	-	-	-	-	-	-
HPMAHIPH_03143	1.26e-55	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
HPMAHIPH_03144	4.32e-258	-	-	-	S	-	-	-	Phage terminase large subunit
HPMAHIPH_03145	2.34e-249	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPMAHIPH_03146	4.32e-124	-	-	-	S	-	-	-	Phage Mu protein F like protein
HPMAHIPH_03148	3.72e-40	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
HPMAHIPH_03149	2.62e-182	-	-	-	-	-	-	-	-
HPMAHIPH_03150	2.22e-60	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HPMAHIPH_03151	3.2e-41	-	-	-	-	-	-	-	-
HPMAHIPH_03152	9.29e-49	-	-	-	S	-	-	-	exonuclease activity
HPMAHIPH_03154	6.58e-108	-	-	-	S	-	-	-	Phage major tail protein 2
HPMAHIPH_03155	5.41e-39	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
HPMAHIPH_03157	6.62e-180	-	-	-	S	-	-	-	peptidoglycan catabolic process
HPMAHIPH_03158	1.99e-134	-	-	-	S	-	-	-	Phage tail protein
HPMAHIPH_03159	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HPMAHIPH_03160	1.95e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HPMAHIPH_03161	1.02e-53	-	-	-	-	-	-	-	-
HPMAHIPH_03162	5.04e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HPMAHIPH_03163	7.74e-158	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HPMAHIPH_03164	2.75e-81	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
HPMAHIPH_03165	2.1e-33	-	-	-	-	-	-	-	-
HPMAHIPH_03166	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_03167	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HPMAHIPH_03168	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HPMAHIPH_03169	4.63e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03170	2.16e-26	-	-	-	-	-	-	-	-
HPMAHIPH_03171	9.35e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03172	9.35e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03173	9.35e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03174	1.07e-26	-	-	-	-	-	-	-	-
HPMAHIPH_03175	1.56e-22	-	-	-	-	-	-	-	-
HPMAHIPH_03176	3.26e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03177	6.58e-24	-	-	-	-	-	-	-	-
HPMAHIPH_03178	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HPMAHIPH_03179	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HPMAHIPH_03180	1.27e-109	-	-	-	K	-	-	-	MarR family
HPMAHIPH_03181	9.28e-58	-	-	-	-	-	-	-	-
HPMAHIPH_03182	5.21e-51	-	-	-	-	-	-	-	-
HPMAHIPH_03183	2.08e-288	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_03187	2.16e-39	-	-	-	-	-	-	-	-
HPMAHIPH_03188	1.13e-180	-	-	-	L	-	-	-	DNA replication protein
HPMAHIPH_03189	1.09e-63	-	-	-	S	-	-	-	Phage plasmid primase P4 family
HPMAHIPH_03191	1e-31	-	-	-	-	-	-	-	-
HPMAHIPH_03192	7.63e-65	-	-	-	S	-	-	-	Head-tail joining protein
HPMAHIPH_03193	1.52e-83	-	-	-	L	-	-	-	HNH endonuclease
HPMAHIPH_03194	9.03e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HPMAHIPH_03195	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HPMAHIPH_03196	0.000495	-	-	-	-	-	-	-	-
HPMAHIPH_03197	8.75e-260	-	-	-	S	-	-	-	Phage portal protein
HPMAHIPH_03198	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HPMAHIPH_03199	5.85e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HPMAHIPH_03200	1.88e-75	-	-	-	-	-	-	-	-
HPMAHIPH_03201	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HPMAHIPH_03202	9.99e-44	-	-	-	-	-	-	-	-
HPMAHIPH_03204	1.98e-40	-	-	-	-	-	-	-	-
HPMAHIPH_03206	3.66e-276	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_03207	2.61e-16	-	-	-	-	-	-	-	-
HPMAHIPH_03210	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HPMAHIPH_03212	1.77e-163	-	-	-	-	-	-	-	-
HPMAHIPH_03214	1.74e-125	-	-	-	-	-	-	-	-
HPMAHIPH_03219	2.83e-25	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
HPMAHIPH_03224	9.75e-16	-	-	-	-	-	-	-	-
HPMAHIPH_03225	5.34e-11	-	-	-	-	-	-	-	-
HPMAHIPH_03226	6.3e-293	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_03228	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPMAHIPH_03229	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPMAHIPH_03230	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPMAHIPH_03231	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPMAHIPH_03232	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HPMAHIPH_03233	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HPMAHIPH_03234	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPMAHIPH_03235	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HPMAHIPH_03236	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HPMAHIPH_03237	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HPMAHIPH_03238	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPMAHIPH_03239	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPMAHIPH_03240	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMAHIPH_03241	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPMAHIPH_03242	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HPMAHIPH_03243	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPMAHIPH_03244	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HPMAHIPH_03245	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HPMAHIPH_03246	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPMAHIPH_03247	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HPMAHIPH_03248	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HPMAHIPH_03249	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPMAHIPH_03250	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HPMAHIPH_03251	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HPMAHIPH_03252	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HPMAHIPH_03253	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HPMAHIPH_03254	3.66e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPMAHIPH_03255	4.82e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HPMAHIPH_03256	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HPMAHIPH_03257	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPMAHIPH_03258	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HPMAHIPH_03259	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HPMAHIPH_03260	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HPMAHIPH_03261	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HPMAHIPH_03262	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HPMAHIPH_03263	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HPMAHIPH_03264	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HPMAHIPH_03265	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
HPMAHIPH_03267	2.4e-80	-	-	-	S	-	-	-	Glycosyl hydrolases family 25
HPMAHIPH_03270	6.4e-50	-	-	-	-	-	-	-	-
HPMAHIPH_03274	0.000165	-	-	-	-	-	-	-	-
HPMAHIPH_03275	4.26e-37	-	-	-	-	-	-	-	-
HPMAHIPH_03276	9.55e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HPMAHIPH_03277	6.85e-178	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_03279	9.48e-36	-	-	-	-	-	-	-	-
HPMAHIPH_03282	9.03e-46	repB	-	-	L	-	-	-	Initiator Replication protein
HPMAHIPH_03286	2.42e-247	-	-	-	S	-	-	-	MobA/MobL family
HPMAHIPH_03287	4.74e-148	-	-	-	-	-	-	-	-
HPMAHIPH_03288	2.5e-70	-	-	-	L	-	-	-	Integrase
HPMAHIPH_03289	1.02e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HPMAHIPH_03290	2.84e-75	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPMAHIPH_03291	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPMAHIPH_03292	1.01e-182	-	-	-	-	-	-	-	-
HPMAHIPH_03294	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HPMAHIPH_03295	3.88e-46	-	-	-	-	-	-	-	-
HPMAHIPH_03296	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HPMAHIPH_03297	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
HPMAHIPH_03298	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HPMAHIPH_03299	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPMAHIPH_03300	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HPMAHIPH_03301	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HPMAHIPH_03302	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_03303	1.36e-27	-	-	-	-	-	-	-	-
HPMAHIPH_03304	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HPMAHIPH_03305	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_03306	3.3e-199	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HPMAHIPH_03307	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HPMAHIPH_03308	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HPMAHIPH_03309	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPMAHIPH_03310	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HPMAHIPH_03311	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPMAHIPH_03312	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HPMAHIPH_03313	1.21e-63	-	-	-	-	-	-	-	-
HPMAHIPH_03314	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HPMAHIPH_03315	6.12e-115	-	-	-	-	-	-	-	-
HPMAHIPH_03316	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HPMAHIPH_03317	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HPMAHIPH_03318	1.48e-27	-	-	-	-	-	-	-	-
HPMAHIPH_03319	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HPMAHIPH_03320	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HPMAHIPH_03321	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HPMAHIPH_03322	1.01e-188	-	-	-	-	-	-	-	-
HPMAHIPH_03323	9.86e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HPMAHIPH_03324	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HPMAHIPH_03325	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMAHIPH_03326	1.23e-52	-	-	-	-	-	-	-	-
HPMAHIPH_03328	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMAHIPH_03329	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HPMAHIPH_03330	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_03331	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HPMAHIPH_03332	1.66e-106	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPMAHIPH_03333	3.85e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HPMAHIPH_03334	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HPMAHIPH_03335	1.83e-181	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HPMAHIPH_03336	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HPMAHIPH_03337	3.1e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMAHIPH_03338	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HPMAHIPH_03339	3.08e-93	-	-	-	K	-	-	-	MarR family
HPMAHIPH_03340	2.27e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HPMAHIPH_03341	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HPMAHIPH_03342	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMAHIPH_03343	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPMAHIPH_03344	1.13e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HPMAHIPH_03345	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HPMAHIPH_03346	1.61e-36	-	-	-	-	-	-	-	-
HPMAHIPH_03347	2.61e-163	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HPMAHIPH_03348	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HPMAHIPH_03349	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HPMAHIPH_03350	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HPMAHIPH_03351	5.26e-142	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HPMAHIPH_03352	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HPMAHIPH_03353	5.95e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HPMAHIPH_03354	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HPMAHIPH_03355	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HPMAHIPH_03356	1.08e-71	-	-	-	-	-	-	-	-
HPMAHIPH_03357	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_03358	0.0	-	-	-	L	-	-	-	AAA domain
HPMAHIPH_03359	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HPMAHIPH_03360	1.85e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPMAHIPH_03361	4.73e-302	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HPMAHIPH_03362	7.04e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HPMAHIPH_03363	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HPMAHIPH_03364	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HPMAHIPH_03365	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HPMAHIPH_03366	1.95e-116	-	-	-	-	-	-	-	-
HPMAHIPH_03367	5.74e-32	-	-	-	-	-	-	-	-
HPMAHIPH_03368	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HPMAHIPH_03369	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HPMAHIPH_03370	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HPMAHIPH_03371	4.25e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HPMAHIPH_03372	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HPMAHIPH_03373	6.27e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HPMAHIPH_03374	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HPMAHIPH_03375	2.88e-48	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
HPMAHIPH_03376	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HPMAHIPH_03377	5.79e-293	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	PFAM N-6 DNA methylase
HPMAHIPH_03378	9.44e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HPMAHIPH_03379	3.64e-219	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMAHIPH_03380	8.86e-28	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HPMAHIPH_03381	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HPMAHIPH_03382	0.0	-	-	-	M	-	-	-	MucBP domain
HPMAHIPH_03383	1.42e-08	-	-	-	-	-	-	-	-
HPMAHIPH_03384	2.36e-111	-	-	-	S	-	-	-	AAA domain
HPMAHIPH_03385	1.06e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
HPMAHIPH_03386	1.88e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMAHIPH_03387	4.4e-217	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_03388	0.0	-	-	-	C	-	-	-	FMN_bind
HPMAHIPH_03390	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HPMAHIPH_03391	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPMAHIPH_03392	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HPMAHIPH_03393	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HPMAHIPH_03394	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HPMAHIPH_03395	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HPMAHIPH_03396	5.44e-56	-	-	-	-	-	-	-	-
HPMAHIPH_03397	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HPMAHIPH_03398	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPMAHIPH_03399	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPMAHIPH_03400	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HPMAHIPH_03401	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HPMAHIPH_03402	1.12e-243	-	-	-	-	-	-	-	-
HPMAHIPH_03403	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HPMAHIPH_03404	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HPMAHIPH_03405	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
HPMAHIPH_03406	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HPMAHIPH_03407	3.33e-64	-	-	-	-	-	-	-	-
HPMAHIPH_03408	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPMAHIPH_03409	0.0	xylP2	-	-	G	-	-	-	symporter
HPMAHIPH_03410	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPMAHIPH_03411	1.7e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HPMAHIPH_03412	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HPMAHIPH_03413	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HPMAHIPH_03414	2.36e-154	azlC	-	-	E	-	-	-	branched-chain amino acid
HPMAHIPH_03415	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein