ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LEPMCGDO_00001 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEPMCGDO_00002 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEPMCGDO_00003 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
LEPMCGDO_00004 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LEPMCGDO_00005 9.9e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEPMCGDO_00006 2.7e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LEPMCGDO_00007 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEPMCGDO_00008 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LEPMCGDO_00009 0.0 ymfH - - S - - - Peptidase M16
LEPMCGDO_00010 7.16e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
LEPMCGDO_00011 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LEPMCGDO_00012 1.51e-198 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LEPMCGDO_00013 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00014 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00015 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LEPMCGDO_00016 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEPMCGDO_00017 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LEPMCGDO_00018 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LEPMCGDO_00019 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LEPMCGDO_00020 1.35e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
LEPMCGDO_00021 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LEPMCGDO_00022 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEPMCGDO_00023 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEPMCGDO_00024 5.71e-302 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
LEPMCGDO_00025 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEPMCGDO_00026 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LEPMCGDO_00027 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEPMCGDO_00028 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LEPMCGDO_00029 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEPMCGDO_00030 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
LEPMCGDO_00031 1.15e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LEPMCGDO_00032 1.06e-140 - - - S - - - Protein of unknown function (DUF1648)
LEPMCGDO_00033 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_00034 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LEPMCGDO_00035 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LEPMCGDO_00036 1.34e-52 - - - - - - - -
LEPMCGDO_00037 2.37e-107 uspA - - T - - - universal stress protein
LEPMCGDO_00038 1.2e-262 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LEPMCGDO_00039 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_00040 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
LEPMCGDO_00041 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LEPMCGDO_00042 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEPMCGDO_00043 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
LEPMCGDO_00044 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LEPMCGDO_00045 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LEPMCGDO_00046 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00047 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEPMCGDO_00048 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
LEPMCGDO_00049 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LEPMCGDO_00050 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
LEPMCGDO_00051 5.3e-58 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LEPMCGDO_00052 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LEPMCGDO_00053 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LEPMCGDO_00054 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEPMCGDO_00055 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LEPMCGDO_00056 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEPMCGDO_00057 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEPMCGDO_00058 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEPMCGDO_00059 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEPMCGDO_00060 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEPMCGDO_00061 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEPMCGDO_00062 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LEPMCGDO_00063 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LEPMCGDO_00064 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LEPMCGDO_00065 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
LEPMCGDO_00066 5.12e-212 - - - K - - - LysR substrate binding domain
LEPMCGDO_00067 1.84e-134 - - - - - - - -
LEPMCGDO_00068 3.7e-30 - - - - - - - -
LEPMCGDO_00069 7.3e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEPMCGDO_00070 3.21e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEPMCGDO_00071 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEPMCGDO_00072 1.56e-108 - - - - - - - -
LEPMCGDO_00073 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LEPMCGDO_00074 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEPMCGDO_00075 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
LEPMCGDO_00076 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
LEPMCGDO_00077 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEPMCGDO_00078 2e-52 - - - S - - - Cytochrome B5
LEPMCGDO_00079 0.0 - - - - - - - -
LEPMCGDO_00080 5.86e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LEPMCGDO_00081 3.2e-203 - - - I - - - alpha/beta hydrolase fold
LEPMCGDO_00082 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
LEPMCGDO_00083 1.15e-296 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
LEPMCGDO_00084 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_00085 2.84e-266 - - - EGP - - - Major facilitator Superfamily
LEPMCGDO_00086 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
LEPMCGDO_00087 0.0 - - - S - - - Predicted membrane protein (DUF2207)
LEPMCGDO_00088 5.69e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LEPMCGDO_00089 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LEPMCGDO_00090 4.05e-285 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_00091 6.3e-169 - - - M - - - Phosphotransferase enzyme family
LEPMCGDO_00092 7.2e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LEPMCGDO_00093 3.99e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
LEPMCGDO_00094 2.15e-195 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LEPMCGDO_00095 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_00096 8.85e-141 - - - K - - - Transcriptional regulator (TetR family)
LEPMCGDO_00097 7.21e-232 yhgE - - V ko:K01421 - ko00000 domain protein
LEPMCGDO_00100 8.96e-317 - - - EGP - - - Major Facilitator
LEPMCGDO_00101 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_00102 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_00104 5.17e-249 - - - C - - - Aldo/keto reductase family
LEPMCGDO_00105 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
LEPMCGDO_00106 9.49e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LEPMCGDO_00107 9.15e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LEPMCGDO_00108 3.88e-41 - - - - - - - -
LEPMCGDO_00109 7.47e-164 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LEPMCGDO_00110 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LEPMCGDO_00111 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
LEPMCGDO_00112 2.21e-46 - - - - - - - -
LEPMCGDO_00113 4.8e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LEPMCGDO_00114 6.77e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LEPMCGDO_00115 1.64e-130 - - - GM - - - NAD(P)H-binding
LEPMCGDO_00116 5.48e-203 - - - K - - - LysR substrate binding domain
LEPMCGDO_00117 1.49e-83 - - - S - - - Domain of unknown function (DUF4440)
LEPMCGDO_00118 1.29e-143 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
LEPMCGDO_00119 2.81e-64 - - - - - - - -
LEPMCGDO_00120 2.8e-49 - - - - - - - -
LEPMCGDO_00121 4.4e-112 yvbK - - K - - - GNAT family
LEPMCGDO_00122 9.82e-111 - - - - - - - -
LEPMCGDO_00123 1.58e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LEPMCGDO_00124 2.44e-149 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LEPMCGDO_00125 5.27e-140 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LEPMCGDO_00126 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEPMCGDO_00128 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00129 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00130 6.13e-298 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LEPMCGDO_00131 1.27e-103 - - - K - - - transcriptional regulator, MerR family
LEPMCGDO_00132 4.77e-100 yphH - - S - - - Cupin domain
LEPMCGDO_00133 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LEPMCGDO_00134 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPMCGDO_00135 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LEPMCGDO_00136 2.45e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00137 5.88e-214 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LEPMCGDO_00138 2.11e-200 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LEPMCGDO_00139 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEPMCGDO_00140 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_00141 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEPMCGDO_00142 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEPMCGDO_00143 0.0 ydaO - - E - - - amino acid
LEPMCGDO_00144 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LEPMCGDO_00145 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LEPMCGDO_00146 2.14e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LEPMCGDO_00147 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LEPMCGDO_00148 5.69e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LEPMCGDO_00149 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEPMCGDO_00150 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEPMCGDO_00151 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEPMCGDO_00152 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
LEPMCGDO_00153 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LEPMCGDO_00154 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEPMCGDO_00155 1.19e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LEPMCGDO_00156 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LEPMCGDO_00157 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LEPMCGDO_00158 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEPMCGDO_00159 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEPMCGDO_00160 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LEPMCGDO_00161 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
LEPMCGDO_00162 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LEPMCGDO_00163 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEPMCGDO_00164 1.42e-209 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEPMCGDO_00165 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LEPMCGDO_00166 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LEPMCGDO_00167 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
LEPMCGDO_00168 0.0 nox - - C - - - NADH oxidase
LEPMCGDO_00169 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEPMCGDO_00170 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
LEPMCGDO_00171 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
LEPMCGDO_00172 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEPMCGDO_00173 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
LEPMCGDO_00174 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPMCGDO_00175 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LEPMCGDO_00176 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
LEPMCGDO_00177 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LEPMCGDO_00178 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEPMCGDO_00179 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEPMCGDO_00180 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEPMCGDO_00181 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEPMCGDO_00182 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LEPMCGDO_00183 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
LEPMCGDO_00184 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LEPMCGDO_00185 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LEPMCGDO_00186 7e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LEPMCGDO_00187 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_00188 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPMCGDO_00189 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEPMCGDO_00191 3.81e-310 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
LEPMCGDO_00192 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LEPMCGDO_00193 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEPMCGDO_00194 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LEPMCGDO_00195 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEPMCGDO_00196 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEPMCGDO_00197 8.51e-163 - - - - - - - -
LEPMCGDO_00198 0.0 eriC - - P ko:K03281 - ko00000 chloride
LEPMCGDO_00199 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LEPMCGDO_00200 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
LEPMCGDO_00201 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEPMCGDO_00202 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEPMCGDO_00203 0.0 - - - M - - - Domain of unknown function (DUF5011)
LEPMCGDO_00204 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_00205 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00206 6.57e-136 - - - - - - - -
LEPMCGDO_00207 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_00208 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEPMCGDO_00209 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LEPMCGDO_00210 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LEPMCGDO_00211 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
LEPMCGDO_00212 9.81e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LEPMCGDO_00213 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LEPMCGDO_00214 1.47e-211 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
LEPMCGDO_00215 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LEPMCGDO_00216 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
LEPMCGDO_00217 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_00218 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
LEPMCGDO_00219 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEPMCGDO_00220 2.18e-182 ybbR - - S - - - YbbR-like protein
LEPMCGDO_00221 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEPMCGDO_00222 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEPMCGDO_00223 9.03e-158 - - - T - - - EAL domain
LEPMCGDO_00224 3.24e-184 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_00225 1.41e-134 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_00226 1.2e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LEPMCGDO_00227 3.38e-70 - - - - - - - -
LEPMCGDO_00228 2.49e-95 - - - - - - - -
LEPMCGDO_00229 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LEPMCGDO_00230 7.34e-180 - - - EGP - - - Transmembrane secretion effector
LEPMCGDO_00231 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LEPMCGDO_00232 2.44e-59 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_00233 4.31e-147 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_00234 4.35e-164 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LEPMCGDO_00235 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LEPMCGDO_00236 9.9e-105 - - - S - - - Domain of unknown function (DUF4811)
LEPMCGDO_00237 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LEPMCGDO_00238 4.38e-222 - - - S - - - Conserved hypothetical protein 698
LEPMCGDO_00239 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_00240 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
LEPMCGDO_00241 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LEPMCGDO_00243 1.12e-86 - - - M - - - LysM domain
LEPMCGDO_00244 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
LEPMCGDO_00245 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEPMCGDO_00246 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEPMCGDO_00247 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEPMCGDO_00248 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEPMCGDO_00249 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEPMCGDO_00250 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LEPMCGDO_00251 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LEPMCGDO_00252 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LEPMCGDO_00253 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LEPMCGDO_00254 6.5e-246 ampC - - V - - - Beta-lactamase
LEPMCGDO_00255 8.57e-41 - - - - - - - -
LEPMCGDO_00256 2.22e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LEPMCGDO_00257 1.33e-77 - - - - - - - -
LEPMCGDO_00258 6.55e-183 - - - - - - - -
LEPMCGDO_00259 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LEPMCGDO_00260 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00261 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
LEPMCGDO_00262 3.45e-181 icaB - - G - - - Polysaccharide deacetylase
LEPMCGDO_00265 1.98e-40 - - - - - - - -
LEPMCGDO_00267 1.28e-51 - - - - - - - -
LEPMCGDO_00268 9.28e-58 - - - - - - - -
LEPMCGDO_00269 1.27e-109 - - - K - - - MarR family
LEPMCGDO_00270 0.0 - - - D - - - nuclear chromosome segregation
LEPMCGDO_00271 0.0 inlJ - - M - - - MucBP domain
LEPMCGDO_00272 6.58e-24 - - - - - - - -
LEPMCGDO_00273 3.26e-24 - - - - - - - -
LEPMCGDO_00274 1.56e-22 - - - - - - - -
LEPMCGDO_00275 1.07e-26 - - - - - - - -
LEPMCGDO_00276 9.35e-24 - - - - - - - -
LEPMCGDO_00277 9.35e-24 - - - - - - - -
LEPMCGDO_00278 9.35e-24 - - - - - - - -
LEPMCGDO_00279 2.16e-26 - - - - - - - -
LEPMCGDO_00280 4.63e-24 - - - - - - - -
LEPMCGDO_00281 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
LEPMCGDO_00282 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LEPMCGDO_00283 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00284 2.1e-33 - - - - - - - -
LEPMCGDO_00285 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LEPMCGDO_00286 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
LEPMCGDO_00287 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
LEPMCGDO_00288 0.0 yclK - - T - - - Histidine kinase
LEPMCGDO_00289 3.41e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LEPMCGDO_00290 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LEPMCGDO_00291 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LEPMCGDO_00292 1.26e-218 - - - EG - - - EamA-like transporter family
LEPMCGDO_00294 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
LEPMCGDO_00295 1.31e-64 - - - - - - - -
LEPMCGDO_00296 1.96e-273 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
LEPMCGDO_00297 1.9e-176 - - - F - - - NUDIX domain
LEPMCGDO_00298 2.68e-32 - - - - - - - -
LEPMCGDO_00300 1.92e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_00301 5.59e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
LEPMCGDO_00302 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
LEPMCGDO_00303 2.29e-48 - - - - - - - -
LEPMCGDO_00304 1.11e-45 - - - - - - - -
LEPMCGDO_00305 4.86e-279 - - - T - - - diguanylate cyclase
LEPMCGDO_00306 0.0 - - - S - - - ABC transporter, ATP-binding protein
LEPMCGDO_00307 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
LEPMCGDO_00308 3.4e-85 - - - K - - - Winged helix DNA-binding domain
LEPMCGDO_00309 2.5e-132 - - - L - - - Integrase
LEPMCGDO_00310 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LEPMCGDO_00311 5.6e-41 - - - - - - - -
LEPMCGDO_00312 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LEPMCGDO_00313 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEPMCGDO_00314 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LEPMCGDO_00315 8.31e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LEPMCGDO_00316 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEPMCGDO_00317 2.19e-290 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LEPMCGDO_00318 1.94e-289 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEPMCGDO_00319 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
LEPMCGDO_00320 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEPMCGDO_00323 0.0 mdr - - EGP - - - Major Facilitator
LEPMCGDO_00324 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEPMCGDO_00325 1.17e-157 - - - - - - - -
LEPMCGDO_00326 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LEPMCGDO_00327 3.91e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
LEPMCGDO_00328 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LEPMCGDO_00329 1.52e-241 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LEPMCGDO_00330 8.01e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LEPMCGDO_00332 1.25e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LEPMCGDO_00333 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
LEPMCGDO_00334 1.25e-124 - - - - - - - -
LEPMCGDO_00335 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
LEPMCGDO_00336 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
LEPMCGDO_00348 1.05e-54 - - - - - - - -
LEPMCGDO_00349 3.31e-30 - - - - - - - -
LEPMCGDO_00350 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LEPMCGDO_00351 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
LEPMCGDO_00352 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
LEPMCGDO_00353 1.74e-125 dpsB - - P - - - Belongs to the Dps family
LEPMCGDO_00354 1.01e-26 - - - - - - - -
LEPMCGDO_00355 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
LEPMCGDO_00356 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
LEPMCGDO_00357 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_00358 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LEPMCGDO_00359 1.77e-235 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LEPMCGDO_00360 7.76e-168 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
LEPMCGDO_00361 5.92e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEPMCGDO_00362 2.92e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LEPMCGDO_00363 2.36e-136 - - - K - - - transcriptional regulator
LEPMCGDO_00364 3.39e-206 - - - S ko:K07045 - ko00000 Amidohydrolase
LEPMCGDO_00365 2.56e-70 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
LEPMCGDO_00366 1.53e-139 - - - - - - - -
LEPMCGDO_00368 5.77e-81 - - - - - - - -
LEPMCGDO_00369 2.15e-71 - - - - - - - -
LEPMCGDO_00370 5.07e-108 - - - M - - - PFAM NLP P60 protein
LEPMCGDO_00371 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
LEPMCGDO_00372 4.45e-38 - - - - - - - -
LEPMCGDO_00373 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LEPMCGDO_00374 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_00375 1.31e-114 - - - K - - - Winged helix DNA-binding domain
LEPMCGDO_00376 2.7e-175 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
LEPMCGDO_00377 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_00378 3.21e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
LEPMCGDO_00379 0.0 - - - - - - - -
LEPMCGDO_00380 9.81e-212 - - - S - - - Protein of unknown function (DUF1002)
LEPMCGDO_00381 1.58e-66 - - - - - - - -
LEPMCGDO_00382 3.74e-123 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
LEPMCGDO_00383 5.94e-118 ymdB - - S - - - Macro domain protein
LEPMCGDO_00384 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEPMCGDO_00385 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
LEPMCGDO_00386 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
LEPMCGDO_00387 2.57e-171 - - - S - - - Putative threonine/serine exporter
LEPMCGDO_00388 3.34e-210 yvgN - - C - - - Aldo keto reductase
LEPMCGDO_00389 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LEPMCGDO_00390 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LEPMCGDO_00391 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
LEPMCGDO_00392 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LEPMCGDO_00393 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LEPMCGDO_00394 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LEPMCGDO_00395 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEPMCGDO_00396 5.08e-122 - - - S - - - SdpI/YhfL protein family
LEPMCGDO_00397 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEPMCGDO_00398 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LEPMCGDO_00399 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEPMCGDO_00400 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPMCGDO_00401 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
LEPMCGDO_00402 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEPMCGDO_00403 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEPMCGDO_00404 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEPMCGDO_00405 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LEPMCGDO_00406 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEPMCGDO_00407 2.79e-145 - - - S - - - membrane
LEPMCGDO_00408 5.72e-99 - - - K - - - LytTr DNA-binding domain
LEPMCGDO_00409 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
LEPMCGDO_00410 0.0 - - - S - - - membrane
LEPMCGDO_00411 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LEPMCGDO_00412 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LEPMCGDO_00413 3.24e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEPMCGDO_00414 2.47e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LEPMCGDO_00415 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LEPMCGDO_00416 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LEPMCGDO_00417 3.99e-142 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LEPMCGDO_00418 1.15e-89 yqhL - - P - - - Rhodanese-like protein
LEPMCGDO_00419 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
LEPMCGDO_00420 1.57e-178 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
LEPMCGDO_00421 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEPMCGDO_00422 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
LEPMCGDO_00423 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LEPMCGDO_00424 2.07e-204 - - - - - - - -
LEPMCGDO_00425 1.56e-231 - - - - - - - -
LEPMCGDO_00426 3.55e-127 - - - S - - - Protein conserved in bacteria
LEPMCGDO_00427 1.87e-74 - - - - - - - -
LEPMCGDO_00428 2.97e-41 - - - - - - - -
LEPMCGDO_00431 9.81e-27 - - - - - - - -
LEPMCGDO_00432 8.15e-125 - - - K - - - Transcriptional regulator
LEPMCGDO_00433 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LEPMCGDO_00434 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LEPMCGDO_00435 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LEPMCGDO_00436 6.04e-249 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LEPMCGDO_00437 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEPMCGDO_00438 2.82e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LEPMCGDO_00439 9.43e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEPMCGDO_00440 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEPMCGDO_00441 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEPMCGDO_00442 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEPMCGDO_00443 2.5e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LEPMCGDO_00444 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LEPMCGDO_00445 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LEPMCGDO_00446 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LEPMCGDO_00447 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00448 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00449 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEPMCGDO_00450 2.75e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_00451 8.28e-73 - - - - - - - -
LEPMCGDO_00452 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LEPMCGDO_00453 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEPMCGDO_00454 5.88e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEPMCGDO_00455 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEPMCGDO_00456 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEPMCGDO_00457 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEPMCGDO_00458 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LEPMCGDO_00459 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LEPMCGDO_00460 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEPMCGDO_00461 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LEPMCGDO_00462 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LEPMCGDO_00463 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LEPMCGDO_00464 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
LEPMCGDO_00465 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LEPMCGDO_00466 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEPMCGDO_00467 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEPMCGDO_00468 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEPMCGDO_00469 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEPMCGDO_00470 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LEPMCGDO_00471 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEPMCGDO_00472 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEPMCGDO_00473 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEPMCGDO_00474 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LEPMCGDO_00475 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LEPMCGDO_00476 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEPMCGDO_00477 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LEPMCGDO_00478 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEPMCGDO_00479 1.03e-66 - - - - - - - -
LEPMCGDO_00480 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LEPMCGDO_00481 2.14e-110 - - - - - - - -
LEPMCGDO_00482 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LEPMCGDO_00483 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
LEPMCGDO_00485 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
LEPMCGDO_00486 4.68e-134 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
LEPMCGDO_00487 2.45e-225 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEPMCGDO_00488 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LEPMCGDO_00489 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LEPMCGDO_00490 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEPMCGDO_00491 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEPMCGDO_00492 1.02e-126 entB - - Q - - - Isochorismatase family
LEPMCGDO_00493 2.13e-228 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
LEPMCGDO_00494 3.14e-251 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LEPMCGDO_00495 1.49e-77 - - - S - - - Protein of unknown function (DUF1648)
LEPMCGDO_00496 1.13e-184 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPMCGDO_00497 1.62e-229 yneE - - K - - - Transcriptional regulator
LEPMCGDO_00498 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEPMCGDO_00499 8.02e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEPMCGDO_00500 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEPMCGDO_00501 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LEPMCGDO_00502 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LEPMCGDO_00503 1.54e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEPMCGDO_00504 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEPMCGDO_00505 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LEPMCGDO_00506 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LEPMCGDO_00507 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEPMCGDO_00508 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LEPMCGDO_00509 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LEPMCGDO_00510 1.75e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LEPMCGDO_00511 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LEPMCGDO_00512 4.35e-206 - - - K - - - LysR substrate binding domain
LEPMCGDO_00513 4.94e-114 ykhA - - I - - - Thioesterase superfamily
LEPMCGDO_00514 2.18e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEPMCGDO_00515 8.6e-121 - - - K - - - transcriptional regulator
LEPMCGDO_00516 0.0 - - - EGP - - - Major Facilitator
LEPMCGDO_00517 1.14e-193 - - - O - - - Band 7 protein
LEPMCGDO_00518 1.48e-71 - - - - - - - -
LEPMCGDO_00519 2.02e-39 - - - - - - - -
LEPMCGDO_00520 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LEPMCGDO_00521 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
LEPMCGDO_00522 6.15e-62 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
LEPMCGDO_00523 2.05e-55 - - - - - - - -
LEPMCGDO_00524 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
LEPMCGDO_00525 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
LEPMCGDO_00526 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
LEPMCGDO_00527 7.27e-211 - - - I - - - Diacylglycerol kinase catalytic domain
LEPMCGDO_00528 1.51e-48 - - - - - - - -
LEPMCGDO_00529 5.79e-21 - - - - - - - -
LEPMCGDO_00530 2.22e-55 - - - S - - - transglycosylase associated protein
LEPMCGDO_00531 4e-40 - - - S - - - CsbD-like
LEPMCGDO_00532 1.06e-53 - - - - - - - -
LEPMCGDO_00533 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LEPMCGDO_00534 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LEPMCGDO_00535 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEPMCGDO_00536 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
LEPMCGDO_00537 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
LEPMCGDO_00538 1.25e-66 - - - - - - - -
LEPMCGDO_00539 3.23e-58 - - - - - - - -
LEPMCGDO_00540 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEPMCGDO_00541 0.0 - - - E ko:K03294 - ko00000 Amino Acid
LEPMCGDO_00542 9.09e-191 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LEPMCGDO_00543 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LEPMCGDO_00544 3.24e-155 - - - S - - - Domain of unknown function (DUF4767)
LEPMCGDO_00545 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LEPMCGDO_00546 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LEPMCGDO_00547 2.27e-245 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LEPMCGDO_00548 3.51e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEPMCGDO_00549 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LEPMCGDO_00550 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LEPMCGDO_00551 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LEPMCGDO_00552 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LEPMCGDO_00553 2.53e-107 ypmB - - S - - - protein conserved in bacteria
LEPMCGDO_00554 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LEPMCGDO_00555 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LEPMCGDO_00556 3.25e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
LEPMCGDO_00558 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEPMCGDO_00559 1.41e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00560 3.19e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LEPMCGDO_00561 7.56e-109 - - - T - - - Universal stress protein family
LEPMCGDO_00562 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_00563 4.86e-235 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LEPMCGDO_00564 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_00565 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LEPMCGDO_00566 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEPMCGDO_00567 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
LEPMCGDO_00568 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEPMCGDO_00570 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LEPMCGDO_00571 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_00572 7.37e-308 - - - P - - - Major Facilitator Superfamily
LEPMCGDO_00573 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LEPMCGDO_00574 7.86e-96 - - - S - - - SnoaL-like domain
LEPMCGDO_00575 7.08e-309 - - - M - - - Glycosyltransferase, group 2 family protein
LEPMCGDO_00576 3.46e-267 mccF - - V - - - LD-carboxypeptidase
LEPMCGDO_00577 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
LEPMCGDO_00578 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
LEPMCGDO_00579 1.68e-233 - - - V - - - LD-carboxypeptidase
LEPMCGDO_00580 4.02e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LEPMCGDO_00581 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_00582 6.79e-249 - - - - - - - -
LEPMCGDO_00583 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
LEPMCGDO_00584 6e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
LEPMCGDO_00585 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LEPMCGDO_00586 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
LEPMCGDO_00587 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LEPMCGDO_00588 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEPMCGDO_00589 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LEPMCGDO_00590 1.1e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEPMCGDO_00591 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
LEPMCGDO_00592 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LEPMCGDO_00593 0.0 - - - S - - - Bacterial membrane protein, YfhO
LEPMCGDO_00594 2.01e-145 - - - G - - - Phosphoglycerate mutase family
LEPMCGDO_00595 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LEPMCGDO_00597 3.06e-165 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
LEPMCGDO_00598 8.49e-92 - - - S - - - LuxR family transcriptional regulator
LEPMCGDO_00599 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
LEPMCGDO_00601 1.87e-117 - - - F - - - NUDIX domain
LEPMCGDO_00602 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00603 5.36e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LEPMCGDO_00604 0.0 FbpA - - K - - - Fibronectin-binding protein
LEPMCGDO_00605 1.97e-87 - - - K - - - Transcriptional regulator
LEPMCGDO_00606 4.53e-205 - - - S - - - EDD domain protein, DegV family
LEPMCGDO_00607 2.03e-100 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
LEPMCGDO_00608 1.96e-168 - - - S - - - Protein of unknown function (DUF975)
LEPMCGDO_00609 2.38e-39 - - - - - - - -
LEPMCGDO_00610 2.37e-65 - - - - - - - -
LEPMCGDO_00611 6.64e-189 - - - C - - - Domain of unknown function (DUF4931)
LEPMCGDO_00612 3.18e-263 pmrB - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_00614 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
LEPMCGDO_00615 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
LEPMCGDO_00616 3.02e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
LEPMCGDO_00617 7.13e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LEPMCGDO_00618 6.68e-173 - - - - - - - -
LEPMCGDO_00619 7.79e-78 - - - - - - - -
LEPMCGDO_00620 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LEPMCGDO_00621 6.75e-290 - - - - - - - -
LEPMCGDO_00622 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LEPMCGDO_00623 3.61e-244 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
LEPMCGDO_00624 3.5e-251 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEPMCGDO_00625 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEPMCGDO_00626 4.87e-123 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LEPMCGDO_00627 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_00628 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LEPMCGDO_00629 7.59e-86 - - - - - - - -
LEPMCGDO_00630 3.03e-313 - - - M - - - Glycosyl transferase family group 2
LEPMCGDO_00631 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEPMCGDO_00632 5.1e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
LEPMCGDO_00633 1.07e-43 - - - S - - - YozE SAM-like fold
LEPMCGDO_00634 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEPMCGDO_00635 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LEPMCGDO_00636 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LEPMCGDO_00637 1.56e-227 - - - K - - - Transcriptional regulator
LEPMCGDO_00638 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEPMCGDO_00639 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEPMCGDO_00640 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEPMCGDO_00641 1.04e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LEPMCGDO_00642 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEPMCGDO_00643 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEPMCGDO_00644 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
LEPMCGDO_00645 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEPMCGDO_00646 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEPMCGDO_00647 4.69e-202 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LEPMCGDO_00648 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEPMCGDO_00649 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEPMCGDO_00650 5.13e-292 XK27_05470 - - E - - - Methionine synthase
LEPMCGDO_00651 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
LEPMCGDO_00652 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
LEPMCGDO_00653 5.01e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LEPMCGDO_00654 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
LEPMCGDO_00655 0.0 qacA - - EGP - - - Major Facilitator
LEPMCGDO_00656 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LEPMCGDO_00657 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
LEPMCGDO_00658 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LEPMCGDO_00659 1.02e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
LEPMCGDO_00660 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
LEPMCGDO_00661 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEPMCGDO_00662 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEPMCGDO_00663 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00664 6.46e-109 - - - - - - - -
LEPMCGDO_00665 1.27e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEPMCGDO_00666 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEPMCGDO_00667 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LEPMCGDO_00668 5.83e-291 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LEPMCGDO_00669 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEPMCGDO_00670 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LEPMCGDO_00671 8.06e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LEPMCGDO_00672 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LEPMCGDO_00673 1.25e-39 - - - M - - - Lysin motif
LEPMCGDO_00674 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LEPMCGDO_00675 3.38e-252 - - - S - - - Helix-turn-helix domain
LEPMCGDO_00676 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEPMCGDO_00677 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LEPMCGDO_00678 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEPMCGDO_00679 1.18e-174 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEPMCGDO_00680 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPMCGDO_00681 2.57e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LEPMCGDO_00682 3.23e-217 yitL - - S ko:K00243 - ko00000 S1 domain
LEPMCGDO_00683 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
LEPMCGDO_00684 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LEPMCGDO_00685 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEPMCGDO_00686 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LEPMCGDO_00687 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
LEPMCGDO_00689 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEPMCGDO_00690 2.6e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LEPMCGDO_00691 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEPMCGDO_00692 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LEPMCGDO_00693 1.75e-295 - - - M - - - O-Antigen ligase
LEPMCGDO_00694 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LEPMCGDO_00695 3.45e-212 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_00696 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_00697 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LEPMCGDO_00698 2.27e-82 - - - P - - - Rhodanese Homology Domain
LEPMCGDO_00699 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_00700 1.93e-266 - - - - - - - -
LEPMCGDO_00701 1.05e-277 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
LEPMCGDO_00702 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
LEPMCGDO_00703 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
LEPMCGDO_00704 1.09e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEPMCGDO_00705 2.28e-307 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
LEPMCGDO_00706 4.38e-102 - - - K - - - Transcriptional regulator
LEPMCGDO_00707 8.57e-270 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LEPMCGDO_00708 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPMCGDO_00709 4.14e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LEPMCGDO_00710 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LEPMCGDO_00711 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
LEPMCGDO_00712 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
LEPMCGDO_00713 4.88e-147 - - - GM - - - epimerase
LEPMCGDO_00714 0.0 - - - S - - - Zinc finger, swim domain protein
LEPMCGDO_00715 9.07e-158 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
LEPMCGDO_00716 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LEPMCGDO_00717 1.44e-166 - - - K - - - Helix-turn-helix domain, rpiR family
LEPMCGDO_00718 2.63e-206 - - - S - - - Alpha beta hydrolase
LEPMCGDO_00719 1.76e-146 - - - GM - - - NmrA-like family
LEPMCGDO_00720 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
LEPMCGDO_00721 5.72e-207 - - - K - - - Transcriptional regulator
LEPMCGDO_00722 6.54e-222 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LEPMCGDO_00724 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPMCGDO_00725 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LEPMCGDO_00726 4.7e-262 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEPMCGDO_00727 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LEPMCGDO_00728 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_00730 1.34e-108 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LEPMCGDO_00731 5.9e-103 - - - K - - - MarR family
LEPMCGDO_00732 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
LEPMCGDO_00733 0.000523 yjdF - - S - - - Protein of unknown function (DUF2992)
LEPMCGDO_00734 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00735 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LEPMCGDO_00736 5.21e-254 - - - - - - - -
LEPMCGDO_00737 3.53e-254 - - - - - - - -
LEPMCGDO_00738 1.42e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00739 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LEPMCGDO_00740 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEPMCGDO_00741 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEPMCGDO_00742 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LEPMCGDO_00743 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LEPMCGDO_00744 4.71e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LEPMCGDO_00745 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEPMCGDO_00746 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LEPMCGDO_00747 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEPMCGDO_00748 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LEPMCGDO_00749 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LEPMCGDO_00750 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LEPMCGDO_00751 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEPMCGDO_00752 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
LEPMCGDO_00753 1.17e-216 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEPMCGDO_00754 7.48e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEPMCGDO_00755 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEPMCGDO_00756 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEPMCGDO_00757 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEPMCGDO_00758 8.26e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LEPMCGDO_00759 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
LEPMCGDO_00760 1.87e-213 - - - G - - - Fructosamine kinase
LEPMCGDO_00761 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
LEPMCGDO_00762 1.17e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEPMCGDO_00763 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEPMCGDO_00764 6.06e-75 - - - - - - - -
LEPMCGDO_00765 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEPMCGDO_00766 1.44e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LEPMCGDO_00767 1.06e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LEPMCGDO_00768 4.78e-65 - - - - - - - -
LEPMCGDO_00769 1.73e-67 - - - - - - - -
LEPMCGDO_00770 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEPMCGDO_00771 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEPMCGDO_00772 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEPMCGDO_00773 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LEPMCGDO_00774 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEPMCGDO_00775 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
LEPMCGDO_00776 8.49e-266 pbpX2 - - V - - - Beta-lactamase
LEPMCGDO_00777 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEPMCGDO_00778 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LEPMCGDO_00779 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEPMCGDO_00780 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEPMCGDO_00781 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LEPMCGDO_00782 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LEPMCGDO_00783 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEPMCGDO_00784 3.99e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEPMCGDO_00785 2.44e-245 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LEPMCGDO_00786 1.92e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEPMCGDO_00787 9.84e-123 - - - - - - - -
LEPMCGDO_00788 9.01e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEPMCGDO_00789 0.0 - - - G - - - Major Facilitator
LEPMCGDO_00790 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEPMCGDO_00791 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEPMCGDO_00792 3.28e-63 ylxQ - - J - - - ribosomal protein
LEPMCGDO_00793 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LEPMCGDO_00794 2.31e-277 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LEPMCGDO_00795 1.97e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LEPMCGDO_00796 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEPMCGDO_00797 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEPMCGDO_00798 1.55e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LEPMCGDO_00799 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LEPMCGDO_00800 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEPMCGDO_00801 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEPMCGDO_00802 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LEPMCGDO_00803 2.67e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEPMCGDO_00804 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LEPMCGDO_00805 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
LEPMCGDO_00806 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPMCGDO_00807 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LEPMCGDO_00808 3.4e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LEPMCGDO_00809 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LEPMCGDO_00810 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
LEPMCGDO_00811 7.68e-48 ynzC - - S - - - UPF0291 protein
LEPMCGDO_00812 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEPMCGDO_00813 6.4e-122 - - - - - - - -
LEPMCGDO_00814 1.1e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LEPMCGDO_00815 1.94e-97 - - - - - - - -
LEPMCGDO_00816 3.81e-87 - - - - - - - -
LEPMCGDO_00817 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
LEPMCGDO_00818 6.27e-131 - - - L - - - Helix-turn-helix domain
LEPMCGDO_00819 3.91e-276 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
LEPMCGDO_00820 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_00821 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_00822 3.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
LEPMCGDO_00825 3.19e-50 - - - S - - - Haemolysin XhlA
LEPMCGDO_00826 3.43e-259 - - - M - - - Glycosyl hydrolases family 25
LEPMCGDO_00827 3.02e-72 - - - - - - - -
LEPMCGDO_00831 0.0 - - - S - - - Phage minor structural protein
LEPMCGDO_00832 9.23e-290 - - - S - - - Phage tail protein
LEPMCGDO_00833 7.6e-104 - - - D - - - domain protein
LEPMCGDO_00834 0.0 - - - D - - - domain protein
LEPMCGDO_00835 2.09e-26 - - - - - - - -
LEPMCGDO_00836 3.88e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
LEPMCGDO_00837 1.42e-138 - - - S - - - Phage tail tube protein
LEPMCGDO_00838 6.66e-77 - - - S - - - Protein of unknown function (DUF806)
LEPMCGDO_00839 1.65e-88 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LEPMCGDO_00840 6.96e-76 - - - S - - - Phage head-tail joining protein
LEPMCGDO_00841 5.42e-64 - - - S - - - Phage gp6-like head-tail connector protein
LEPMCGDO_00842 2.01e-269 - - - S - - - Phage capsid family
LEPMCGDO_00843 5.74e-162 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LEPMCGDO_00844 2.43e-284 - - - S - - - Phage portal protein
LEPMCGDO_00845 1.64e-35 - - - S - - - Protein of unknown function (DUF1056)
LEPMCGDO_00846 0.0 - - - S - - - Phage Terminase
LEPMCGDO_00847 7.49e-102 - - - S - - - Phage terminase, small subunit
LEPMCGDO_00850 2.72e-113 - - - L - - - HNH nucleases
LEPMCGDO_00851 1.01e-17 - - - V - - - HNH nucleases
LEPMCGDO_00852 3.02e-112 - - - - - - - -
LEPMCGDO_00853 4.28e-80 - - - S - - - Transcriptional regulator, RinA family
LEPMCGDO_00854 1.19e-61 - - - - - - - -
LEPMCGDO_00856 4.21e-171 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LEPMCGDO_00857 2.23e-94 - - - L - - - DnaD domain protein
LEPMCGDO_00860 4.56e-12 - - - - - - - -
LEPMCGDO_00866 1.22e-33 - - - - - - - -
LEPMCGDO_00868 1.31e-117 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
LEPMCGDO_00870 3.49e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_00871 6.22e-48 - - - S - - - Pfam:Peptidase_M78
LEPMCGDO_00876 3.53e-32 - - - - - - - -
LEPMCGDO_00881 1.55e-75 int3 - - L - - - Belongs to the 'phage' integrase family
LEPMCGDO_00882 1.75e-43 - - - - - - - -
LEPMCGDO_00883 4.15e-183 - - - Q - - - Methyltransferase
LEPMCGDO_00884 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
LEPMCGDO_00885 2.35e-269 - - - EGP - - - Major facilitator Superfamily
LEPMCGDO_00886 4.57e-135 - - - K - - - Helix-turn-helix domain
LEPMCGDO_00887 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEPMCGDO_00888 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LEPMCGDO_00889 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
LEPMCGDO_00890 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPMCGDO_00891 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEPMCGDO_00892 6.62e-62 - - - - - - - -
LEPMCGDO_00893 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEPMCGDO_00894 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LEPMCGDO_00895 7.34e-219 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LEPMCGDO_00896 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LEPMCGDO_00897 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
LEPMCGDO_00898 0.0 cps4J - - S - - - MatE
LEPMCGDO_00899 8.34e-229 cps4I - - M - - - Glycosyltransferase like family 2
LEPMCGDO_00900 3.38e-291 - - - - - - - -
LEPMCGDO_00901 7.75e-235 cps4G - - M - - - Glycosyltransferase Family 4
LEPMCGDO_00902 1.63e-258 cps4F - - M - - - Glycosyl transferases group 1
LEPMCGDO_00903 5.71e-165 tuaA - - M - - - Bacterial sugar transferase
LEPMCGDO_00904 6.86e-228 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LEPMCGDO_00905 4.18e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LEPMCGDO_00906 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
LEPMCGDO_00907 8.45e-162 epsB - - M - - - biosynthesis protein
LEPMCGDO_00908 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEPMCGDO_00909 1.62e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_00910 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LEPMCGDO_00911 5.12e-31 - - - - - - - -
LEPMCGDO_00912 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
LEPMCGDO_00913 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
LEPMCGDO_00914 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LEPMCGDO_00915 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEPMCGDO_00916 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEPMCGDO_00917 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEPMCGDO_00918 1.97e-202 - - - S - - - Tetratricopeptide repeat
LEPMCGDO_00919 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEPMCGDO_00920 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEPMCGDO_00921 4.48e-261 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_00922 2.39e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEPMCGDO_00923 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LEPMCGDO_00924 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LEPMCGDO_00925 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LEPMCGDO_00926 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LEPMCGDO_00927 3.85e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LEPMCGDO_00928 3.01e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LEPMCGDO_00929 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEPMCGDO_00930 2.03e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LEPMCGDO_00931 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LEPMCGDO_00932 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEPMCGDO_00933 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LEPMCGDO_00934 0.0 - - - - - - - -
LEPMCGDO_00935 0.0 icaA - - M - - - Glycosyl transferase family group 2
LEPMCGDO_00936 9.51e-135 - - - - - - - -
LEPMCGDO_00937 1.75e-47 - - - K - - - MerR HTH family regulatory protein
LEPMCGDO_00938 2.03e-155 azlC - - E - - - branched-chain amino acid
LEPMCGDO_00939 9.83e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LEPMCGDO_00940 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LEPMCGDO_00941 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
LEPMCGDO_00942 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEPMCGDO_00943 0.0 xylP2 - - G - - - symporter
LEPMCGDO_00944 3.48e-245 - - - I - - - alpha/beta hydrolase fold
LEPMCGDO_00945 3.33e-64 - - - - - - - -
LEPMCGDO_00946 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
LEPMCGDO_00947 1.22e-132 - - - K - - - FR47-like protein
LEPMCGDO_00948 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
LEPMCGDO_00949 1.46e-281 yibE - - S - - - overlaps another CDS with the same product name
LEPMCGDO_00950 1.94e-244 - - - - - - - -
LEPMCGDO_00951 5.03e-180 - - - S - - - NADPH-dependent FMN reductase
LEPMCGDO_00952 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_00953 1.65e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LEPMCGDO_00954 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LEPMCGDO_00955 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
LEPMCGDO_00956 9.05e-55 - - - - - - - -
LEPMCGDO_00957 5.38e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEPMCGDO_00958 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LEPMCGDO_00959 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LEPMCGDO_00960 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LEPMCGDO_00961 1.41e-150 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEPMCGDO_00962 3.54e-105 - - - K - - - Transcriptional regulator
LEPMCGDO_00964 0.0 - - - C - - - FMN_bind
LEPMCGDO_00965 2.28e-219 - - - K - - - Transcriptional regulator
LEPMCGDO_00966 1.88e-124 - - - K - - - Helix-turn-helix domain
LEPMCGDO_00967 1.83e-180 - - - K - - - sequence-specific DNA binding
LEPMCGDO_00968 1.27e-115 - - - S - - - AAA domain
LEPMCGDO_00969 1.42e-08 - - - - - - - -
LEPMCGDO_00970 0.0 - - - M - - - MucBP domain
LEPMCGDO_00971 1.28e-31 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
LEPMCGDO_00972 1.15e-69 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
LEPMCGDO_00974 9.97e-108 - - - L - - - PFAM Integrase catalytic region
LEPMCGDO_00975 4.92e-69 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
LEPMCGDO_00976 1.55e-61 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LEPMCGDO_00977 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LEPMCGDO_00978 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LEPMCGDO_00979 4.1e-281 - - - S - - - PglZ domain
LEPMCGDO_00980 4.68e-201 - - - V - - - Eco57I restriction-modification methylase
LEPMCGDO_00981 2.15e-189 - - - L - - - Belongs to the 'phage' integrase family
LEPMCGDO_00982 0.0 - - - LV - - - Eco57I restriction-modification methylase
LEPMCGDO_00983 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LEPMCGDO_00984 1.15e-93 - - - S - - - Domain of unknown function (DUF1788)
LEPMCGDO_00985 1.77e-83 - - - S - - - Putative inner membrane protein (DUF1819)
LEPMCGDO_00986 5.69e-182 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
LEPMCGDO_00987 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LEPMCGDO_00988 3.27e-215 yjdB - - S - - - Domain of unknown function (DUF4767)
LEPMCGDO_00989 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
LEPMCGDO_00990 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
LEPMCGDO_00991 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
LEPMCGDO_00992 5.74e-32 - - - - - - - -
LEPMCGDO_00993 1.95e-116 - - - - - - - -
LEPMCGDO_00994 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
LEPMCGDO_00995 0.0 XK27_09800 - - I - - - Acyltransferase family
LEPMCGDO_00996 3.61e-61 - - - S - - - MORN repeat
LEPMCGDO_00997 4.65e-307 - - - S - - - Cysteine-rich secretory protein family
LEPMCGDO_00998 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
LEPMCGDO_00999 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
LEPMCGDO_01000 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_01001 0.0 - - - L - - - AAA domain
LEPMCGDO_01002 1.37e-83 - - - K - - - Helix-turn-helix domain
LEPMCGDO_01003 1.08e-71 - - - - - - - -
LEPMCGDO_01004 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LEPMCGDO_01005 1.5e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LEPMCGDO_01006 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
LEPMCGDO_01007 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LEPMCGDO_01008 2.84e-146 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
LEPMCGDO_01009 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LEPMCGDO_01010 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LEPMCGDO_01011 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
LEPMCGDO_01012 2.23e-164 pgm3 - - G - - - Phosphoglycerate mutase family
LEPMCGDO_01013 1.61e-36 - - - - - - - -
LEPMCGDO_01014 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
LEPMCGDO_01015 4.6e-102 rppH3 - - F - - - NUDIX domain
LEPMCGDO_01016 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEPMCGDO_01017 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01018 1.19e-108 - - - S ko:K07090 - ko00000 membrane transporter protein
LEPMCGDO_01019 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_01020 3.08e-93 - - - K - - - MarR family
LEPMCGDO_01021 1.47e-189 - - - S - - - Sulfite exporter TauE/SafE
LEPMCGDO_01022 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_01023 0.0 steT - - E ko:K03294 - ko00000 amino acid
LEPMCGDO_01024 2.22e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
LEPMCGDO_01025 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LEPMCGDO_01026 4.68e-198 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LEPMCGDO_01027 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEPMCGDO_01028 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_01029 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_01030 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LEPMCGDO_01031 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_01033 1.28e-54 - - - - - - - -
LEPMCGDO_01034 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPMCGDO_01035 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEPMCGDO_01036 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
LEPMCGDO_01037 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_01038 1.76e-293 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LEPMCGDO_01039 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LEPMCGDO_01040 3.8e-135 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LEPMCGDO_01041 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LEPMCGDO_01042 1.17e-135 - - - K - - - transcriptional regulator
LEPMCGDO_01043 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LEPMCGDO_01044 1.49e-63 - - - - - - - -
LEPMCGDO_01045 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LEPMCGDO_01046 7.18e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LEPMCGDO_01047 2.87e-56 - - - - - - - -
LEPMCGDO_01048 3.35e-75 - - - - - - - -
LEPMCGDO_01049 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_01050 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
LEPMCGDO_01051 2.42e-65 - - - - - - - -
LEPMCGDO_01052 1.56e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
LEPMCGDO_01053 1.18e-315 hpk2 - - T - - - Histidine kinase
LEPMCGDO_01054 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_01055 0.0 ydiC - - EGP - - - Major Facilitator
LEPMCGDO_01056 1.55e-55 - - - - - - - -
LEPMCGDO_01057 2.92e-57 - - - - - - - -
LEPMCGDO_01058 1.15e-152 - - - - - - - -
LEPMCGDO_01059 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LEPMCGDO_01060 1.05e-155 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01061 8.9e-96 ywnA - - K - - - Transcriptional regulator
LEPMCGDO_01062 9.53e-93 - - - - - - - -
LEPMCGDO_01063 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LEPMCGDO_01064 2.6e-185 - - - - - - - -
LEPMCGDO_01065 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LEPMCGDO_01066 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_01067 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LEPMCGDO_01068 6.84e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LEPMCGDO_01069 2.21e-56 - - - - - - - -
LEPMCGDO_01070 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
LEPMCGDO_01071 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LEPMCGDO_01072 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LEPMCGDO_01073 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LEPMCGDO_01074 8.21e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LEPMCGDO_01075 2.13e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
LEPMCGDO_01076 5.78e-245 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
LEPMCGDO_01077 4.98e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
LEPMCGDO_01078 2.92e-258 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
LEPMCGDO_01079 1.73e-269 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
LEPMCGDO_01080 7.59e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LEPMCGDO_01081 3.56e-52 - - - - - - - -
LEPMCGDO_01082 4.08e-291 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_01083 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LEPMCGDO_01084 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LEPMCGDO_01085 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
LEPMCGDO_01086 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LEPMCGDO_01087 1.22e-89 - - - - - - - -
LEPMCGDO_01088 2.03e-124 - - - - - - - -
LEPMCGDO_01089 5.92e-67 - - - - - - - -
LEPMCGDO_01090 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LEPMCGDO_01091 2.43e-111 - - - - - - - -
LEPMCGDO_01092 2.5e-280 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LEPMCGDO_01093 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_01094 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LEPMCGDO_01095 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_01096 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LEPMCGDO_01097 2.46e-126 - - - K - - - Helix-turn-helix domain
LEPMCGDO_01098 1.3e-281 - - - C - - - FAD dependent oxidoreductase
LEPMCGDO_01099 2.22e-221 - - - P - - - Major Facilitator Superfamily
LEPMCGDO_01100 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEPMCGDO_01101 1.11e-87 - - - - - - - -
LEPMCGDO_01102 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEPMCGDO_01103 5.3e-202 dkgB - - S - - - reductase
LEPMCGDO_01104 3.52e-116 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LEPMCGDO_01105 8.25e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
LEPMCGDO_01106 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEPMCGDO_01107 4.3e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LEPMCGDO_01108 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_01109 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEPMCGDO_01110 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEPMCGDO_01111 3.81e-18 - - - - - - - -
LEPMCGDO_01112 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEPMCGDO_01113 3.91e-211 fbpA - - K - - - Domain of unknown function (DUF814)
LEPMCGDO_01114 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
LEPMCGDO_01115 6.33e-46 - - - - - - - -
LEPMCGDO_01116 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LEPMCGDO_01117 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
LEPMCGDO_01118 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEPMCGDO_01119 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPMCGDO_01120 1.54e-101 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LEPMCGDO_01121 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_01122 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_01123 1.7e-200 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LEPMCGDO_01125 0.0 - - - M - - - domain protein
LEPMCGDO_01126 0.0 - - - N - - - domain, Protein
LEPMCGDO_01127 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
LEPMCGDO_01128 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
LEPMCGDO_01129 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LEPMCGDO_01130 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LEPMCGDO_01131 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEPMCGDO_01132 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
LEPMCGDO_01133 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LEPMCGDO_01134 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEPMCGDO_01135 7.74e-47 - - - - - - - -
LEPMCGDO_01136 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LEPMCGDO_01137 1.41e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEPMCGDO_01138 2.05e-20 - - - S - - - Protein of unknown function (DUF3021)
LEPMCGDO_01139 2.57e-47 - - - K - - - LytTr DNA-binding domain
LEPMCGDO_01140 1.47e-100 - - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LEPMCGDO_01141 3.64e-101 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
LEPMCGDO_01142 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEPMCGDO_01143 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LEPMCGDO_01144 2.06e-187 ylmH - - S - - - S4 domain protein
LEPMCGDO_01145 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
LEPMCGDO_01146 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEPMCGDO_01147 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEPMCGDO_01148 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEPMCGDO_01149 4.05e-209 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEPMCGDO_01150 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEPMCGDO_01151 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEPMCGDO_01152 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEPMCGDO_01153 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LEPMCGDO_01154 7.01e-76 ftsL - - D - - - Cell division protein FtsL
LEPMCGDO_01155 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEPMCGDO_01156 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LEPMCGDO_01157 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
LEPMCGDO_01158 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LEPMCGDO_01159 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LEPMCGDO_01160 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEPMCGDO_01161 5.88e-146 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LEPMCGDO_01162 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LEPMCGDO_01164 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LEPMCGDO_01165 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEPMCGDO_01166 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
LEPMCGDO_01167 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LEPMCGDO_01168 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LEPMCGDO_01169 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
LEPMCGDO_01170 1.27e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LEPMCGDO_01171 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEPMCGDO_01172 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LEPMCGDO_01173 2.24e-148 yjbH - - Q - - - Thioredoxin
LEPMCGDO_01174 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LEPMCGDO_01175 6.44e-264 coiA - - S ko:K06198 - ko00000 Competence protein
LEPMCGDO_01176 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEPMCGDO_01177 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEPMCGDO_01178 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
LEPMCGDO_01179 4.4e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LEPMCGDO_01199 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEPMCGDO_01200 3.69e-185 - - - - - - - -
LEPMCGDO_01202 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
LEPMCGDO_01203 3.88e-46 - - - - - - - -
LEPMCGDO_01204 4.2e-117 - - - V - - - VanZ like family
LEPMCGDO_01205 1.02e-312 - - - EGP - - - Major Facilitator
LEPMCGDO_01206 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LEPMCGDO_01207 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LEPMCGDO_01208 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LEPMCGDO_01209 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
LEPMCGDO_01210 6.16e-107 - - - K - - - Transcriptional regulator
LEPMCGDO_01211 1.36e-27 - - - - - - - -
LEPMCGDO_01212 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LEPMCGDO_01213 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_01214 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LEPMCGDO_01215 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_01216 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LEPMCGDO_01217 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEPMCGDO_01218 0.0 oatA - - I - - - Acyltransferase
LEPMCGDO_01219 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEPMCGDO_01220 1.89e-90 - - - O - - - OsmC-like protein
LEPMCGDO_01221 1.09e-60 - - - - - - - -
LEPMCGDO_01222 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
LEPMCGDO_01223 6.12e-115 - - - - - - - -
LEPMCGDO_01224 5.24e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LEPMCGDO_01225 7.48e-96 - - - F - - - Nudix hydrolase
LEPMCGDO_01226 1.48e-27 - - - - - - - -
LEPMCGDO_01227 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
LEPMCGDO_01228 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LEPMCGDO_01229 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
LEPMCGDO_01230 1.01e-188 - - - - - - - -
LEPMCGDO_01231 1.11e-84 - - - - - - - -
LEPMCGDO_01232 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
LEPMCGDO_01233 7.33e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEPMCGDO_01234 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LEPMCGDO_01235 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
LEPMCGDO_01236 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEPMCGDO_01237 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
LEPMCGDO_01238 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LEPMCGDO_01239 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
LEPMCGDO_01240 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LEPMCGDO_01241 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEPMCGDO_01242 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LEPMCGDO_01244 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
LEPMCGDO_01245 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
LEPMCGDO_01246 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
LEPMCGDO_01247 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LEPMCGDO_01248 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LEPMCGDO_01249 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LEPMCGDO_01250 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEPMCGDO_01251 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
LEPMCGDO_01252 8.49e-66 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
LEPMCGDO_01253 6.48e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
LEPMCGDO_01254 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LEPMCGDO_01255 2.57e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LEPMCGDO_01256 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_01257 1.6e-96 - - - - - - - -
LEPMCGDO_01258 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEPMCGDO_01259 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LEPMCGDO_01260 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEPMCGDO_01261 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEPMCGDO_01262 7.94e-114 ykuL - - S - - - (CBS) domain
LEPMCGDO_01263 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LEPMCGDO_01264 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEPMCGDO_01265 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LEPMCGDO_01266 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
LEPMCGDO_01267 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LEPMCGDO_01268 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEPMCGDO_01269 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEPMCGDO_01270 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
LEPMCGDO_01271 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEPMCGDO_01272 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
LEPMCGDO_01273 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEPMCGDO_01274 2.05e-315 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEPMCGDO_01275 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LEPMCGDO_01276 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEPMCGDO_01277 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LEPMCGDO_01278 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEPMCGDO_01279 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEPMCGDO_01280 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEPMCGDO_01281 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEPMCGDO_01282 2.42e-117 - - - - - - - -
LEPMCGDO_01283 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LEPMCGDO_01284 1.35e-93 - - - - - - - -
LEPMCGDO_01285 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEPMCGDO_01286 1.38e-155 csrR - - K - - - response regulator
LEPMCGDO_01287 7.66e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LEPMCGDO_01288 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEPMCGDO_01289 6.29e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEPMCGDO_01290 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
LEPMCGDO_01291 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LEPMCGDO_01292 2.05e-278 ylbM - - S - - - Belongs to the UPF0348 family
LEPMCGDO_01293 3.3e-180 yqeM - - Q - - - Methyltransferase
LEPMCGDO_01294 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEPMCGDO_01295 1.71e-149 yqeK - - H - - - Hydrolase, HD family
LEPMCGDO_01296 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEPMCGDO_01297 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LEPMCGDO_01298 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LEPMCGDO_01299 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LEPMCGDO_01300 6.32e-114 - - - - - - - -
LEPMCGDO_01301 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
LEPMCGDO_01302 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LEPMCGDO_01303 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
LEPMCGDO_01304 1.49e-253 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEPMCGDO_01305 6.02e-308 - - - L ko:K07478 - ko00000 AAA C-terminal domain
LEPMCGDO_01306 9.27e-73 - - - - - - - -
LEPMCGDO_01307 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEPMCGDO_01308 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LEPMCGDO_01309 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEPMCGDO_01310 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEPMCGDO_01311 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LEPMCGDO_01312 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LEPMCGDO_01313 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEPMCGDO_01314 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEPMCGDO_01315 5.3e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEPMCGDO_01316 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEPMCGDO_01317 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LEPMCGDO_01318 6.66e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_01319 1.79e-125 - - - S - - - Protein of unknown function (DUF2975)
LEPMCGDO_01320 4.4e-97 - - - - - - - -
LEPMCGDO_01321 1.1e-228 - - - - - - - -
LEPMCGDO_01322 1.89e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
LEPMCGDO_01323 2.1e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
LEPMCGDO_01324 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
LEPMCGDO_01325 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEPMCGDO_01326 3.91e-245 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
LEPMCGDO_01327 1.57e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LEPMCGDO_01328 5.2e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
LEPMCGDO_01329 9.62e-116 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LEPMCGDO_01330 4.24e-109 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEPMCGDO_01331 2.33e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEPMCGDO_01332 8.84e-52 - - - - - - - -
LEPMCGDO_01333 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
LEPMCGDO_01334 1.21e-243 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
LEPMCGDO_01335 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
LEPMCGDO_01336 3.67e-65 - - - - - - - -
LEPMCGDO_01337 6.4e-235 - - - - - - - -
LEPMCGDO_01338 2.16e-208 - - - H - - - geranyltranstransferase activity
LEPMCGDO_01339 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LEPMCGDO_01340 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
LEPMCGDO_01341 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
LEPMCGDO_01342 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEPMCGDO_01343 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
LEPMCGDO_01344 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
LEPMCGDO_01345 6.7e-107 - - - C - - - Flavodoxin
LEPMCGDO_01346 2.79e-212 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPMCGDO_01347 1.14e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LEPMCGDO_01348 7.63e-249 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LEPMCGDO_01349 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LEPMCGDO_01350 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LEPMCGDO_01351 9.08e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEPMCGDO_01352 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LEPMCGDO_01353 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LEPMCGDO_01354 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
LEPMCGDO_01355 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LEPMCGDO_01356 3.04e-29 - - - S - - - Virus attachment protein p12 family
LEPMCGDO_01357 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LEPMCGDO_01358 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LEPMCGDO_01359 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEPMCGDO_01360 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
LEPMCGDO_01361 2.8e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEPMCGDO_01362 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
LEPMCGDO_01363 3.32e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_01364 4.47e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_01365 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LEPMCGDO_01366 6.76e-73 - - - - - - - -
LEPMCGDO_01367 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEPMCGDO_01368 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_01369 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_01370 9.24e-246 - - - S - - - Fn3-like domain
LEPMCGDO_01371 1.65e-80 - - - - - - - -
LEPMCGDO_01372 0.0 - - - - - - - -
LEPMCGDO_01373 3e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LEPMCGDO_01374 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01375 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
LEPMCGDO_01376 3.39e-138 - - - - - - - -
LEPMCGDO_01377 6.08e-136 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
LEPMCGDO_01378 3.01e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEPMCGDO_01379 1.86e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LEPMCGDO_01380 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LEPMCGDO_01381 3.49e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEPMCGDO_01382 0.0 - - - S - - - membrane
LEPMCGDO_01383 1.4e-90 - - - S - - - NUDIX domain
LEPMCGDO_01384 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEPMCGDO_01385 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
LEPMCGDO_01386 1.18e-100 - - - S ko:K03975 - ko00000 SNARE-like domain protein
LEPMCGDO_01387 5.57e-168 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LEPMCGDO_01388 7.93e-79 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
LEPMCGDO_01389 1.73e-134 llrE - - K - - - Transcriptional regulatory protein, C terminal
LEPMCGDO_01390 3.72e-203 - - - T - - - Histidine kinase
LEPMCGDO_01391 2.27e-98 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
LEPMCGDO_01392 2.57e-128 - - - - - - - -
LEPMCGDO_01393 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LEPMCGDO_01394 8.14e-143 - - - S - - - NADPH-dependent FMN reductase
LEPMCGDO_01395 6.59e-227 - - - K - - - LysR substrate binding domain
LEPMCGDO_01396 1.45e-234 - - - M - - - Peptidase family S41
LEPMCGDO_01397 1.58e-277 - - - - - - - -
LEPMCGDO_01398 4.2e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPMCGDO_01399 0.0 yhaN - - L - - - AAA domain
LEPMCGDO_01400 1.05e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
LEPMCGDO_01401 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
LEPMCGDO_01402 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LEPMCGDO_01403 2.43e-18 - - - - - - - -
LEPMCGDO_01404 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LEPMCGDO_01405 1.31e-269 arcT - - E - - - Aminotransferase
LEPMCGDO_01406 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
LEPMCGDO_01407 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
LEPMCGDO_01408 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEPMCGDO_01409 3.47e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
LEPMCGDO_01410 2.57e-273 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
LEPMCGDO_01411 3.61e-137 - - - - - - - -
LEPMCGDO_01412 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LEPMCGDO_01413 3.81e-105 - - - - - - - -
LEPMCGDO_01414 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LEPMCGDO_01415 1.21e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
LEPMCGDO_01418 1.79e-42 - - - - - - - -
LEPMCGDO_01419 2.51e-315 dinF - - V - - - MatE
LEPMCGDO_01420 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
LEPMCGDO_01421 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
LEPMCGDO_01422 4.22e-224 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
LEPMCGDO_01423 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LEPMCGDO_01424 1.8e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
LEPMCGDO_01425 0.0 - - - S - - - Protein conserved in bacteria
LEPMCGDO_01426 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEPMCGDO_01427 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEPMCGDO_01428 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
LEPMCGDO_01429 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
LEPMCGDO_01430 3.89e-237 - - - - - - - -
LEPMCGDO_01431 9.03e-16 - - - - - - - -
LEPMCGDO_01432 4.29e-87 - - - - - - - -
LEPMCGDO_01434 1.14e-135 - - - M - - - Glycosyl hydrolases family 25
LEPMCGDO_01435 5.04e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
LEPMCGDO_01437 4.34e-55 - - - - - - - -
LEPMCGDO_01440 6.98e-143 - - - LM - - - DNA recombination
LEPMCGDO_01442 1.14e-213 - - - L - - - Phage tail tape measure protein TP901
LEPMCGDO_01444 3.79e-44 - - - S - - - Phage tail tube protein
LEPMCGDO_01445 1.3e-28 - - - - - - - -
LEPMCGDO_01446 1.32e-44 - - - - - - - -
LEPMCGDO_01447 4.96e-31 - - - - - - - -
LEPMCGDO_01448 1.01e-24 - - - - - - - -
LEPMCGDO_01449 2.59e-140 - - - S - - - Phage capsid family
LEPMCGDO_01450 5.71e-71 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
LEPMCGDO_01451 4.07e-127 - - - S - - - Phage portal protein
LEPMCGDO_01452 9.32e-224 - - - S - - - Phage Terminase
LEPMCGDO_01453 1.51e-18 - - - - - - - -
LEPMCGDO_01459 2.02e-43 - - - - - - - -
LEPMCGDO_01463 7.72e-51 - - - S - - - hydrolase activity, acting on ester bonds
LEPMCGDO_01464 6.4e-166 - - - S ko:K06919 - ko00000 Virulence-associated protein E
LEPMCGDO_01465 2.31e-95 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
LEPMCGDO_01466 3.52e-28 - - - - - - - -
LEPMCGDO_01467 3.29e-92 - - - L - - - AAA domain
LEPMCGDO_01468 1.64e-10 - - - S - - - HNH endonuclease
LEPMCGDO_01469 5.54e-221 - - - S - - - helicase activity
LEPMCGDO_01470 3.18e-53 - - - S - - - Siphovirus Gp157
LEPMCGDO_01477 3.08e-36 - - - S - - - Domain of unknown function (DUF771)
LEPMCGDO_01478 3.08e-11 - - - - - - - -
LEPMCGDO_01479 9.87e-28 - - - - - - - -
LEPMCGDO_01480 1.08e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_01485 1.34e-86 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
LEPMCGDO_01486 4.52e-120 int3 - - L - - - Belongs to the 'phage' integrase family
LEPMCGDO_01488 0.0 uvrA2 - - L - - - ABC transporter
LEPMCGDO_01489 7.12e-62 - - - - - - - -
LEPMCGDO_01490 8.82e-119 - - - - - - - -
LEPMCGDO_01491 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
LEPMCGDO_01492 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_01493 4.56e-78 - - - - - - - -
LEPMCGDO_01494 5.37e-74 - - - - - - - -
LEPMCGDO_01495 3.14e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LEPMCGDO_01496 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LEPMCGDO_01497 7.83e-140 - - - - - - - -
LEPMCGDO_01498 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_01499 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEPMCGDO_01500 3.86e-150 - - - GM - - - NAD(P)H-binding
LEPMCGDO_01501 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_01502 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEPMCGDO_01504 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
LEPMCGDO_01505 1.77e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_01506 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
LEPMCGDO_01508 0.0 XK27_06930 - - V ko:K01421 - ko00000 domain protein
LEPMCGDO_01509 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEPMCGDO_01510 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
LEPMCGDO_01511 7.43e-160 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LEPMCGDO_01512 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LEPMCGDO_01513 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_01514 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_01515 1.19e-257 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
LEPMCGDO_01516 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
LEPMCGDO_01517 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LEPMCGDO_01518 3.03e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEPMCGDO_01519 2.05e-175 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LEPMCGDO_01520 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LEPMCGDO_01521 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LEPMCGDO_01522 6.19e-162 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LEPMCGDO_01523 5.13e-138 mraW1 - - J - - - Putative rRNA methylase
LEPMCGDO_01524 9.32e-40 - - - - - - - -
LEPMCGDO_01525 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LEPMCGDO_01526 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LEPMCGDO_01527 0.0 - - - S - - - Pfam Methyltransferase
LEPMCGDO_01528 3.21e-26 - - - N - - - Cell shape-determining protein MreB
LEPMCGDO_01530 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
LEPMCGDO_01531 1.57e-184 - - - S - - - Peptidase_C39 like family
LEPMCGDO_01532 6.23e-236 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LEPMCGDO_01533 1.27e-143 - - - - - - - -
LEPMCGDO_01534 4.93e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEPMCGDO_01535 1.97e-110 - - - S - - - Pfam:DUF3816
LEPMCGDO_01536 4.11e-61 - - - V - - - HNH nucleases
LEPMCGDO_01537 3.79e-84 - - - S - - - AAA ATPase domain
LEPMCGDO_01538 1.92e-18 - - - S - - - Transcriptional regulator, RinA family
LEPMCGDO_01542 1.75e-47 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LEPMCGDO_01543 3.68e-105 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LEPMCGDO_01544 7.03e-33 - - - L - - - DnaD domain protein
LEPMCGDO_01549 1.07e-08 - - - - - - - -
LEPMCGDO_01552 5.85e-16 kilA - - L - - - Phage regulatory protein
LEPMCGDO_01553 3.54e-22 - - - S - - - AntA/AntB antirepressor
LEPMCGDO_01554 1.25e-13 - - - K - - - ORF6N domain
LEPMCGDO_01555 3.15e-63 - - - K - - - ORF6N domain
LEPMCGDO_01557 2.14e-27 - - - K - - - Transcriptional regulator, Cro CI family
LEPMCGDO_01559 4.15e-11 - - - - - - - -
LEPMCGDO_01560 1.13e-75 - - - L - - - Transposase and inactivated derivatives, IS30 family
LEPMCGDO_01561 1.01e-37 - - - L - - - Transposase and inactivated derivatives, IS30 family
LEPMCGDO_01565 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
LEPMCGDO_01566 1.94e-245 mocA - - S - - - Oxidoreductase
LEPMCGDO_01567 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LEPMCGDO_01568 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
LEPMCGDO_01569 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LEPMCGDO_01570 5.63e-196 gntR - - K - - - rpiR family
LEPMCGDO_01571 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_01572 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_01573 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
LEPMCGDO_01574 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01575 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEPMCGDO_01576 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LEPMCGDO_01577 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEPMCGDO_01578 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEPMCGDO_01579 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEPMCGDO_01580 9.48e-263 camS - - S - - - sex pheromone
LEPMCGDO_01581 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEPMCGDO_01582 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LEPMCGDO_01583 5.68e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEPMCGDO_01584 1.13e-120 yebE - - S - - - UPF0316 protein
LEPMCGDO_01585 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEPMCGDO_01586 9.78e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LEPMCGDO_01587 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LEPMCGDO_01588 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LEPMCGDO_01589 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LEPMCGDO_01590 1.09e-207 - - - S - - - L,D-transpeptidase catalytic domain
LEPMCGDO_01591 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LEPMCGDO_01592 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEPMCGDO_01593 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LEPMCGDO_01594 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LEPMCGDO_01595 0.0 - - - S ko:K06889 - ko00000 Alpha beta
LEPMCGDO_01596 6.07e-33 - - - - - - - -
LEPMCGDO_01597 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
LEPMCGDO_01598 0.0 - - - E ko:K03294 - ko00000 Amino Acid
LEPMCGDO_01599 9.09e-213 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LEPMCGDO_01600 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LEPMCGDO_01601 6.5e-215 mleR - - K - - - LysR family
LEPMCGDO_01602 2.62e-206 mleR2 - - K - - - LysR family transcriptional regulator
LEPMCGDO_01603 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LEPMCGDO_01604 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LEPMCGDO_01605 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEPMCGDO_01606 2.06e-219 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEPMCGDO_01607 1.38e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEPMCGDO_01609 3.47e-33 - - - K - - - sequence-specific DNA binding
LEPMCGDO_01610 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LEPMCGDO_01611 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LEPMCGDO_01612 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LEPMCGDO_01613 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LEPMCGDO_01614 3.19e-263 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
LEPMCGDO_01615 8.69e-230 citR - - K - - - sugar-binding domain protein
LEPMCGDO_01616 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LEPMCGDO_01617 7.56e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LEPMCGDO_01618 1.18e-66 - - - - - - - -
LEPMCGDO_01619 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LEPMCGDO_01620 7.15e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LEPMCGDO_01621 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEPMCGDO_01622 4.49e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LEPMCGDO_01623 1.49e-252 - - - K - - - Helix-turn-helix domain
LEPMCGDO_01624 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
LEPMCGDO_01625 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
LEPMCGDO_01626 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
LEPMCGDO_01627 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LEPMCGDO_01628 6.18e-216 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEPMCGDO_01629 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
LEPMCGDO_01630 2.45e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEPMCGDO_01631 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEPMCGDO_01632 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
LEPMCGDO_01633 2.46e-235 - - - S - - - Membrane
LEPMCGDO_01634 1.41e-208 yitS - - S - - - Uncharacterised protein, DegV family COG1307
LEPMCGDO_01635 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LEPMCGDO_01636 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEPMCGDO_01637 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEPMCGDO_01638 1.68e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPMCGDO_01639 3.47e-212 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPMCGDO_01640 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPMCGDO_01641 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEPMCGDO_01642 3.19e-194 - - - S - - - FMN_bind
LEPMCGDO_01643 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LEPMCGDO_01644 5.37e-112 - - - S - - - NusG domain II
LEPMCGDO_01645 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
LEPMCGDO_01646 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LEPMCGDO_01647 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LEPMCGDO_01648 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPMCGDO_01649 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEPMCGDO_01650 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEPMCGDO_01651 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEPMCGDO_01652 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEPMCGDO_01653 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEPMCGDO_01654 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LEPMCGDO_01655 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LEPMCGDO_01656 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEPMCGDO_01657 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEPMCGDO_01658 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEPMCGDO_01659 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEPMCGDO_01660 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEPMCGDO_01661 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEPMCGDO_01662 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEPMCGDO_01663 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEPMCGDO_01664 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LEPMCGDO_01665 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEPMCGDO_01666 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEPMCGDO_01667 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEPMCGDO_01668 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEPMCGDO_01669 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEPMCGDO_01670 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEPMCGDO_01671 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LEPMCGDO_01672 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEPMCGDO_01673 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LEPMCGDO_01674 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEPMCGDO_01675 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEPMCGDO_01676 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEPMCGDO_01677 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LEPMCGDO_01678 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPMCGDO_01679 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPMCGDO_01680 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01681 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEPMCGDO_01682 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LEPMCGDO_01690 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEPMCGDO_01691 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
LEPMCGDO_01692 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LEPMCGDO_01693 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LEPMCGDO_01694 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_01695 1.7e-118 - - - K - - - Transcriptional regulator
LEPMCGDO_01696 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LEPMCGDO_01697 3.88e-198 - - - I - - - alpha/beta hydrolase fold
LEPMCGDO_01698 4.15e-153 - - - I - - - phosphatase
LEPMCGDO_01699 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LEPMCGDO_01700 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
LEPMCGDO_01701 4.6e-169 - - - S - - - Putative threonine/serine exporter
LEPMCGDO_01702 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LEPMCGDO_01703 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
LEPMCGDO_01704 5.53e-77 - - - - - - - -
LEPMCGDO_01705 7.79e-112 - - - K - - - MerR HTH family regulatory protein
LEPMCGDO_01706 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LEPMCGDO_01707 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
LEPMCGDO_01708 1.1e-257 - - - - - - - -
LEPMCGDO_01709 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LEPMCGDO_01710 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LEPMCGDO_01711 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
LEPMCGDO_01712 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
LEPMCGDO_01713 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LEPMCGDO_01714 9.59e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEPMCGDO_01715 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LEPMCGDO_01716 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LEPMCGDO_01717 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEPMCGDO_01718 6.45e-111 - - - - - - - -
LEPMCGDO_01719 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
LEPMCGDO_01720 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEPMCGDO_01721 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LEPMCGDO_01722 2.16e-39 - - - - - - - -
LEPMCGDO_01723 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LEPMCGDO_01724 1.6e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEPMCGDO_01725 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEPMCGDO_01726 1.02e-155 - - - S - - - repeat protein
LEPMCGDO_01727 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
LEPMCGDO_01728 4.77e-08 - - - L ko:K07487 - ko00000 Transposase
LEPMCGDO_01729 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
LEPMCGDO_01730 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LEPMCGDO_01731 1.49e-58 - - - S - - - Cupredoxin-like domain
LEPMCGDO_01732 1.36e-84 - - - S - - - Cupredoxin-like domain
LEPMCGDO_01733 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LEPMCGDO_01734 2.81e-181 - - - K - - - Helix-turn-helix domain
LEPMCGDO_01735 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
LEPMCGDO_01736 4.34e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LEPMCGDO_01737 0.0 - - - - - - - -
LEPMCGDO_01738 3.15e-98 - - - - - - - -
LEPMCGDO_01739 2.85e-243 - - - S - - - Cell surface protein
LEPMCGDO_01740 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_01741 4.62e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
LEPMCGDO_01742 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
LEPMCGDO_01743 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
LEPMCGDO_01744 1.59e-243 ynjC - - S - - - Cell surface protein
LEPMCGDO_01745 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_01746 1.47e-83 - - - - - - - -
LEPMCGDO_01747 8.75e-306 - - - NU - - - Mycoplasma protein of unknown function, DUF285
LEPMCGDO_01748 4.13e-157 - - - - - - - -
LEPMCGDO_01749 1.83e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
LEPMCGDO_01750 2.21e-76 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LEPMCGDO_01751 5.43e-156 ORF00048 - - - - - - -
LEPMCGDO_01752 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
LEPMCGDO_01753 7.04e-270 - - - EGP - - - Major Facilitator
LEPMCGDO_01754 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
LEPMCGDO_01755 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LEPMCGDO_01756 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LEPMCGDO_01757 1.03e-281 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LEPMCGDO_01758 3.75e-129 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01759 3.09e-215 - - - GM - - - NmrA-like family
LEPMCGDO_01760 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LEPMCGDO_01761 0.0 - - - M - - - Glycosyl hydrolases family 25
LEPMCGDO_01762 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
LEPMCGDO_01763 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
LEPMCGDO_01764 3.27e-170 - - - S - - - KR domain
LEPMCGDO_01765 2.75e-124 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01766 5.76e-243 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
LEPMCGDO_01767 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
LEPMCGDO_01768 2.3e-228 ydhF - - S - - - Aldo keto reductase
LEPMCGDO_01769 0.0 yfjF - - U - - - Sugar (and other) transporter
LEPMCGDO_01770 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01771 4.08e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LEPMCGDO_01772 3.69e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEPMCGDO_01773 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPMCGDO_01774 1.92e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPMCGDO_01775 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01776 3.89e-210 - - - GM - - - NmrA-like family
LEPMCGDO_01777 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPMCGDO_01778 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LEPMCGDO_01779 4.31e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LEPMCGDO_01780 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_01781 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LEPMCGDO_01782 9.02e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
LEPMCGDO_01783 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_01784 2.44e-263 - - - NU - - - Mycoplasma protein of unknown function, DUF285
LEPMCGDO_01785 1.97e-151 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01786 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEPMCGDO_01787 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
LEPMCGDO_01788 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
LEPMCGDO_01789 1.29e-206 - - - K - - - LysR substrate binding domain
LEPMCGDO_01790 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LEPMCGDO_01791 0.0 - - - S - - - MucBP domain
LEPMCGDO_01792 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LEPMCGDO_01793 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
LEPMCGDO_01794 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_01795 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_01796 2.09e-85 - - - - - - - -
LEPMCGDO_01797 5.15e-16 - - - - - - - -
LEPMCGDO_01798 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LEPMCGDO_01799 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_01800 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
LEPMCGDO_01801 1.91e-280 - - - S - - - Membrane
LEPMCGDO_01802 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
LEPMCGDO_01803 5.35e-139 yoaZ - - S - - - intracellular protease amidase
LEPMCGDO_01804 1.35e-55 - - - K - - - HxlR-like helix-turn-helix
LEPMCGDO_01805 2.45e-77 - - - - - - - -
LEPMCGDO_01806 1.18e-80 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_01807 1.24e-64 - - - K - - - Helix-turn-helix domain
LEPMCGDO_01808 4.32e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
LEPMCGDO_01809 5.19e-50 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
LEPMCGDO_01810 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEPMCGDO_01811 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
LEPMCGDO_01812 5.7e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LEPMCGDO_01813 1.93e-139 - - - GM - - - NAD(P)H-binding
LEPMCGDO_01814 5.35e-102 - - - GM - - - SnoaL-like domain
LEPMCGDO_01815 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
LEPMCGDO_01816 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
LEPMCGDO_01817 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_01818 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
LEPMCGDO_01819 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
LEPMCGDO_01821 6.79e-53 - - - - - - - -
LEPMCGDO_01822 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEPMCGDO_01823 1.87e-232 ydbI - - K - - - AI-2E family transporter
LEPMCGDO_01824 7.62e-270 xylR - - GK - - - ROK family
LEPMCGDO_01825 6.04e-150 - - - - - - - -
LEPMCGDO_01826 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LEPMCGDO_01827 2e-211 - - - - - - - -
LEPMCGDO_01828 6.77e-259 pkn2 - - KLT - - - Protein tyrosine kinase
LEPMCGDO_01829 7.82e-34 - - - S - - - Protein of unknown function (DUF4064)
LEPMCGDO_01830 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
LEPMCGDO_01831 7.97e-98 - - - S - - - Psort location Cytoplasmic, score
LEPMCGDO_01832 2.12e-72 - - - - - - - -
LEPMCGDO_01834 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
LEPMCGDO_01835 5.93e-73 - - - S - - - branched-chain amino acid
LEPMCGDO_01836 2.05e-167 - - - E - - - branched-chain amino acid
LEPMCGDO_01837 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LEPMCGDO_01838 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LEPMCGDO_01839 5.61e-273 hpk31 - - T - - - Histidine kinase
LEPMCGDO_01840 1.14e-159 vanR - - K - - - response regulator
LEPMCGDO_01841 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
LEPMCGDO_01842 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEPMCGDO_01843 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEPMCGDO_01844 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
LEPMCGDO_01845 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEPMCGDO_01846 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LEPMCGDO_01847 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LEPMCGDO_01848 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LEPMCGDO_01849 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LEPMCGDO_01850 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LEPMCGDO_01851 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
LEPMCGDO_01852 3.45e-198 - - - S - - - Bacterial membrane protein, YfhO
LEPMCGDO_01853 2.12e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_01854 1.37e-215 - - - K - - - LysR substrate binding domain
LEPMCGDO_01855 1.2e-301 - - - EK - - - Aminotransferase, class I
LEPMCGDO_01856 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LEPMCGDO_01857 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_01858 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_01859 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LEPMCGDO_01860 8.83e-127 - - - KT - - - response to antibiotic
LEPMCGDO_01861 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_01862 6.03e-133 - - - S - - - Protein of unknown function (DUF1700)
LEPMCGDO_01863 1.01e-203 - - - S - - - Putative adhesin
LEPMCGDO_01864 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_01865 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LEPMCGDO_01866 2.6e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LEPMCGDO_01867 3.73e-263 - - - S - - - DUF218 domain
LEPMCGDO_01868 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LEPMCGDO_01869 7.19e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_01870 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEPMCGDO_01871 6.26e-101 - - - - - - - -
LEPMCGDO_01872 4.17e-263 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
LEPMCGDO_01873 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_01874 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
LEPMCGDO_01875 1.1e-297 - - - - - - - -
LEPMCGDO_01876 3.91e-211 - - - K - - - LysR substrate binding domain
LEPMCGDO_01877 5.67e-196 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
LEPMCGDO_01878 3.54e-190 - - - S - - - haloacid dehalogenase-like hydrolase
LEPMCGDO_01879 3.75e-103 - - - K - - - MerR family regulatory protein
LEPMCGDO_01880 2.16e-199 - - - GM - - - NmrA-like family
LEPMCGDO_01881 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_01882 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
LEPMCGDO_01884 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
LEPMCGDO_01885 8.44e-304 - - - S - - - module of peptide synthetase
LEPMCGDO_01886 1.41e-136 - - - - - - - -
LEPMCGDO_01887 1.28e-113 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LEPMCGDO_01888 1.28e-77 - - - S - - - Enterocin A Immunity
LEPMCGDO_01889 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
LEPMCGDO_01890 1.54e-214 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
LEPMCGDO_01891 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
LEPMCGDO_01892 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
LEPMCGDO_01893 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
LEPMCGDO_01894 1.9e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
LEPMCGDO_01895 1.03e-34 - - - - - - - -
LEPMCGDO_01896 4.23e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
LEPMCGDO_01897 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
LEPMCGDO_01898 4.22e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
LEPMCGDO_01899 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
LEPMCGDO_01900 1.17e-250 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LEPMCGDO_01901 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LEPMCGDO_01902 2.49e-73 - - - S - - - Enterocin A Immunity
LEPMCGDO_01903 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEPMCGDO_01904 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEPMCGDO_01905 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEPMCGDO_01906 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LEPMCGDO_01907 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEPMCGDO_01909 6.56e-107 - - - - - - - -
LEPMCGDO_01910 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
LEPMCGDO_01912 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LEPMCGDO_01913 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEPMCGDO_01914 1.54e-228 ydbI - - K - - - AI-2E family transporter
LEPMCGDO_01915 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LEPMCGDO_01916 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LEPMCGDO_01917 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LEPMCGDO_01918 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LEPMCGDO_01919 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_01920 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LEPMCGDO_01921 7.73e-132 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_01923 2.77e-30 - - - - - - - -
LEPMCGDO_01925 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LEPMCGDO_01926 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
LEPMCGDO_01927 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
LEPMCGDO_01928 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LEPMCGDO_01929 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
LEPMCGDO_01930 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LEPMCGDO_01931 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEPMCGDO_01932 4.26e-109 cvpA - - S - - - Colicin V production protein
LEPMCGDO_01933 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LEPMCGDO_01934 8.83e-317 - - - EGP - - - Major Facilitator
LEPMCGDO_01936 4.54e-54 - - - - - - - -
LEPMCGDO_01937 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
LEPMCGDO_01938 0.0 cadA - - P - - - P-type ATPase
LEPMCGDO_01940 8.84e-160 - - - S - - - YjbR
LEPMCGDO_01941 1.58e-283 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LEPMCGDO_01942 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEPMCGDO_01943 7.12e-256 glmS2 - - M - - - SIS domain
LEPMCGDO_01944 1.56e-29 - - - S - - - Belongs to the LOG family
LEPMCGDO_01945 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LEPMCGDO_01946 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LEPMCGDO_01947 2.48e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_01948 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
LEPMCGDO_01949 1.12e-208 - - - GM - - - NmrA-like family
LEPMCGDO_01950 3.04e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
LEPMCGDO_01951 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
LEPMCGDO_01952 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
LEPMCGDO_01953 1.7e-70 - - - - - - - -
LEPMCGDO_01954 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
LEPMCGDO_01955 2.11e-82 - - - - - - - -
LEPMCGDO_01956 1.36e-112 - - - - - - - -
LEPMCGDO_01957 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LEPMCGDO_01958 2.27e-74 - - - - - - - -
LEPMCGDO_01959 4.79e-21 - - - - - - - -
LEPMCGDO_01960 3.57e-150 - - - GM - - - NmrA-like family
LEPMCGDO_01961 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
LEPMCGDO_01962 1.63e-203 - - - EG - - - EamA-like transporter family
LEPMCGDO_01963 2.66e-155 - - - S - - - membrane
LEPMCGDO_01964 1.47e-144 - - - S - - - VIT family
LEPMCGDO_01965 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LEPMCGDO_01966 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LEPMCGDO_01967 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LEPMCGDO_01968 4.26e-54 - - - - - - - -
LEPMCGDO_01969 8.43e-97 - - - S - - - COG NOG18757 non supervised orthologous group
LEPMCGDO_01970 3.57e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LEPMCGDO_01971 7.21e-35 - - - - - - - -
LEPMCGDO_01972 4.39e-66 - - - - - - - -
LEPMCGDO_01973 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
LEPMCGDO_01974 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LEPMCGDO_01975 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LEPMCGDO_01976 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
LEPMCGDO_01977 1.44e-99 - - - K - - - Domain of unknown function (DUF1836)
LEPMCGDO_01978 5.05e-08 - - - L ko:K07487 - ko00000 Transposase
LEPMCGDO_01979 9.38e-139 pncA - - Q - - - Isochorismatase family
LEPMCGDO_01980 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEPMCGDO_01981 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
LEPMCGDO_01982 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LEPMCGDO_01983 2.38e-225 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LEPMCGDO_01984 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
LEPMCGDO_01985 1.48e-201 ccpB - - K - - - lacI family
LEPMCGDO_01986 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_01987 7.74e-205 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEPMCGDO_01988 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
LEPMCGDO_01989 2.57e-128 - - - C - - - Nitroreductase family
LEPMCGDO_01990 1.73e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
LEPMCGDO_01991 7.24e-250 - - - S - - - domain, Protein
LEPMCGDO_01992 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_01993 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LEPMCGDO_01994 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
LEPMCGDO_01995 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEPMCGDO_01996 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
LEPMCGDO_01997 0.0 - - - M - - - domain protein
LEPMCGDO_01998 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LEPMCGDO_01999 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
LEPMCGDO_02000 1.45e-46 - - - - - - - -
LEPMCGDO_02001 3.17e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEPMCGDO_02002 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEPMCGDO_02003 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
LEPMCGDO_02004 4.03e-66 - - - S - - - Domain of unknown function (DU1801)
LEPMCGDO_02005 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LEPMCGDO_02006 3.72e-283 ysaA - - V - - - RDD family
LEPMCGDO_02007 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
LEPMCGDO_02008 2.3e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEPMCGDO_02009 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEPMCGDO_02010 1.11e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEPMCGDO_02011 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LEPMCGDO_02012 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEPMCGDO_02013 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEPMCGDO_02014 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEPMCGDO_02015 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LEPMCGDO_02016 4.37e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
LEPMCGDO_02017 3.68e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEPMCGDO_02018 7.09e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LEPMCGDO_02019 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
LEPMCGDO_02020 3.32e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
LEPMCGDO_02021 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LEPMCGDO_02022 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02023 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEPMCGDO_02024 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_02025 8.88e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LEPMCGDO_02026 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LEPMCGDO_02027 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
LEPMCGDO_02028 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
LEPMCGDO_02029 8.46e-239 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEPMCGDO_02030 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LEPMCGDO_02031 9.2e-62 - - - - - - - -
LEPMCGDO_02032 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPMCGDO_02033 4.74e-52 - - - - - - - -
LEPMCGDO_02035 0.0 - - - M - - - domain protein
LEPMCGDO_02036 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_02037 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LEPMCGDO_02038 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEPMCGDO_02039 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
LEPMCGDO_02040 1.1e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02041 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEPMCGDO_02042 2.01e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
LEPMCGDO_02043 5.74e-44 - - - - - - - -
LEPMCGDO_02044 7.18e-60 - - - - - - - -
LEPMCGDO_02046 1.35e-30 - - - S - - - Barstar (barnase inhibitor)
LEPMCGDO_02048 3.56e-70 - - - S - - - SMI1-KNR4 cell-wall
LEPMCGDO_02050 1.35e-167 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LEPMCGDO_02051 6.61e-229 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LEPMCGDO_02052 6.91e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LEPMCGDO_02053 2.27e-259 cps3D - - - - - - -
LEPMCGDO_02054 1.69e-144 cps3E - - - - - - -
LEPMCGDO_02055 2.71e-199 cps3F - - - - - - -
LEPMCGDO_02056 1.24e-256 cps3H - - - - - - -
LEPMCGDO_02057 5.67e-257 cps3I - - G - - - Acyltransferase family
LEPMCGDO_02058 8.42e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
LEPMCGDO_02059 1.47e-305 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LEPMCGDO_02060 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LEPMCGDO_02061 9.02e-70 - - - - - - - -
LEPMCGDO_02062 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
LEPMCGDO_02063 1.95e-41 - - - - - - - -
LEPMCGDO_02064 8.39e-38 - - - - - - - -
LEPMCGDO_02065 4.14e-132 - - - K - - - DNA-templated transcription, initiation
LEPMCGDO_02066 2.82e-170 - - - - - - - -
LEPMCGDO_02067 4.1e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LEPMCGDO_02068 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LEPMCGDO_02069 3.53e-170 lytE - - M - - - NlpC/P60 family
LEPMCGDO_02070 3.97e-64 - - - K - - - sequence-specific DNA binding
LEPMCGDO_02071 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
LEPMCGDO_02072 1.67e-166 pbpX - - V - - - Beta-lactamase
LEPMCGDO_02073 8.52e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LEPMCGDO_02074 1.13e-257 yueF - - S - - - AI-2E family transporter
LEPMCGDO_02075 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
LEPMCGDO_02076 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
LEPMCGDO_02077 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LEPMCGDO_02078 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LEPMCGDO_02079 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LEPMCGDO_02080 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEPMCGDO_02081 0.0 - - - - - - - -
LEPMCGDO_02082 2.12e-252 - - - M - - - MucBP domain
LEPMCGDO_02083 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
LEPMCGDO_02084 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
LEPMCGDO_02085 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
LEPMCGDO_02086 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_02087 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPMCGDO_02088 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPMCGDO_02089 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEPMCGDO_02090 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEPMCGDO_02091 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LEPMCGDO_02092 1.13e-183 - - - S - - - zinc-ribbon domain
LEPMCGDO_02094 3.54e-49 - - - - - - - -
LEPMCGDO_02095 2.99e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
LEPMCGDO_02096 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LEPMCGDO_02097 0.0 - - - I - - - acetylesterase activity
LEPMCGDO_02098 6.34e-301 - - - M - - - Collagen binding domain
LEPMCGDO_02099 1.4e-205 yicL - - EG - - - EamA-like transporter family
LEPMCGDO_02100 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
LEPMCGDO_02101 3.53e-227 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
LEPMCGDO_02102 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
LEPMCGDO_02103 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
LEPMCGDO_02104 4.54e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
LEPMCGDO_02105 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LEPMCGDO_02106 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
LEPMCGDO_02107 8.08e-154 ydgI3 - - C - - - Nitroreductase family
LEPMCGDO_02108 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LEPMCGDO_02109 2e-148 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_02110 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEPMCGDO_02111 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_02112 0.0 - - - - - - - -
LEPMCGDO_02113 1.2e-83 - - - - - - - -
LEPMCGDO_02114 9.55e-243 - - - S - - - Cell surface protein
LEPMCGDO_02115 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_02116 1.15e-125 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LEPMCGDO_02117 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_02118 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
LEPMCGDO_02119 3.79e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LEPMCGDO_02120 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LEPMCGDO_02121 2.1e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
LEPMCGDO_02123 1.15e-43 - - - - - - - -
LEPMCGDO_02124 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
LEPMCGDO_02125 2.88e-106 gtcA3 - - S - - - GtrA-like protein
LEPMCGDO_02126 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_02127 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LEPMCGDO_02128 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
LEPMCGDO_02129 7.03e-62 - - - - - - - -
LEPMCGDO_02130 1.81e-150 - - - S - - - SNARE associated Golgi protein
LEPMCGDO_02131 2.46e-64 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
LEPMCGDO_02132 4.57e-123 - - - P - - - Cadmium resistance transporter
LEPMCGDO_02133 3.93e-99 - - - T - - - Universal stress protein family
LEPMCGDO_02134 4.68e-315 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_02135 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_02137 7.62e-97 - - - - - - - -
LEPMCGDO_02138 2.9e-139 - - - - - - - -
LEPMCGDO_02139 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LEPMCGDO_02140 1.15e-281 pbpX - - V - - - Beta-lactamase
LEPMCGDO_02141 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEPMCGDO_02142 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LEPMCGDO_02143 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_02144 1.87e-44 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
LEPMCGDO_02145 1.33e-49 - - - M ko:K07271 - ko00000,ko01000 LicD family
LEPMCGDO_02147 2.76e-54 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 COG0463, glycosyltransferases involved in cell wall biogenesis
LEPMCGDO_02148 9.43e-68 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEPMCGDO_02150 1.64e-15 - 2.7.10.1 - D ko:K08252 - ko00000,ko01000 Chain length determinant protein tyrosine kinase EpsG
LEPMCGDO_02151 5.42e-28 - - - V - - - Beta-lactamase
LEPMCGDO_02152 1.23e-69 - - - M - - - Glycosyl transferases group 1
LEPMCGDO_02153 5.09e-162 cps2I - - S - - - Psort location CytoplasmicMembrane, score
LEPMCGDO_02154 1.86e-188 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEPMCGDO_02155 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEPMCGDO_02156 5.68e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEPMCGDO_02157 9.86e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEPMCGDO_02159 7.96e-119 - - - - - - - -
LEPMCGDO_02160 1.46e-123 - - - L - - - Integrase
LEPMCGDO_02161 2.66e-172 - - - - - - - -
LEPMCGDO_02162 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_02163 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
LEPMCGDO_02164 7.2e-61 - - - S - - - Enterocin A Immunity
LEPMCGDO_02165 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
LEPMCGDO_02166 0.0 pepF2 - - E - - - Oligopeptidase F
LEPMCGDO_02167 1.4e-95 - - - K - - - Transcriptional regulator
LEPMCGDO_02168 1.86e-210 - - - - - - - -
LEPMCGDO_02169 1.23e-75 - - - - - - - -
LEPMCGDO_02170 1.14e-62 - - - - - - - -
LEPMCGDO_02171 5.99e-213 mleR - - K - - - LysR substrate binding domain
LEPMCGDO_02172 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LEPMCGDO_02173 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LEPMCGDO_02174 1.16e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LEPMCGDO_02175 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LEPMCGDO_02176 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
LEPMCGDO_02177 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LEPMCGDO_02178 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_02179 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LEPMCGDO_02180 1.8e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LEPMCGDO_02181 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
LEPMCGDO_02182 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
LEPMCGDO_02183 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LEPMCGDO_02184 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEPMCGDO_02185 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
LEPMCGDO_02186 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
LEPMCGDO_02187 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_02188 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_02189 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LEPMCGDO_02190 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LEPMCGDO_02191 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
LEPMCGDO_02192 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
LEPMCGDO_02193 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_02194 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LEPMCGDO_02195 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LEPMCGDO_02196 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LEPMCGDO_02197 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
LEPMCGDO_02198 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_02199 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
LEPMCGDO_02200 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
LEPMCGDO_02201 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_02202 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LEPMCGDO_02203 1.73e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_02204 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
LEPMCGDO_02205 3.37e-115 - - - - - - - -
LEPMCGDO_02206 3.16e-191 - - - - - - - -
LEPMCGDO_02207 1.82e-181 - - - - - - - -
LEPMCGDO_02208 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
LEPMCGDO_02209 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LEPMCGDO_02210 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
LEPMCGDO_02211 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02212 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LEPMCGDO_02213 2.08e-264 - - - C - - - Oxidoreductase
LEPMCGDO_02214 0.0 - - - - - - - -
LEPMCGDO_02215 5.05e-114 - - - - - - - -
LEPMCGDO_02216 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LEPMCGDO_02217 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
LEPMCGDO_02218 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
LEPMCGDO_02219 3.07e-204 morA - - S - - - reductase
LEPMCGDO_02221 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
LEPMCGDO_02222 7.71e-66 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_02223 2.19e-289 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LEPMCGDO_02224 2.14e-39 - - - S - - - Protein of unknown function (DUF3021)
LEPMCGDO_02225 2.31e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LEPMCGDO_02226 4.45e-99 - - - K - - - Transcriptional regulator
LEPMCGDO_02227 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LEPMCGDO_02228 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LEPMCGDO_02229 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LEPMCGDO_02230 5.08e-192 - - - I - - - Alpha/beta hydrolase family
LEPMCGDO_02231 5.18e-159 - - - - - - - -
LEPMCGDO_02232 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
LEPMCGDO_02233 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LEPMCGDO_02234 0.0 - - - L - - - HIRAN domain
LEPMCGDO_02235 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LEPMCGDO_02236 3.56e-262 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LEPMCGDO_02237 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEPMCGDO_02238 6.12e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LEPMCGDO_02239 7.6e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEPMCGDO_02240 1.23e-227 - - - C - - - Zinc-binding dehydrogenase
LEPMCGDO_02241 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
LEPMCGDO_02242 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_02243 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
LEPMCGDO_02244 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LEPMCGDO_02245 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
LEPMCGDO_02246 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
LEPMCGDO_02247 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
LEPMCGDO_02248 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
LEPMCGDO_02249 9.38e-190 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LEPMCGDO_02250 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_02251 1.67e-54 - - - - - - - -
LEPMCGDO_02252 2.92e-186 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
LEPMCGDO_02253 4.07e-05 - - - - - - - -
LEPMCGDO_02254 2.4e-180 - - - - - - - -
LEPMCGDO_02255 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LEPMCGDO_02256 2.38e-99 - - - - - - - -
LEPMCGDO_02257 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LEPMCGDO_02258 5.17e-219 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LEPMCGDO_02260 3.61e-303 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LEPMCGDO_02261 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEPMCGDO_02262 1.77e-236 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LEPMCGDO_02263 1.4e-162 - - - S - - - DJ-1/PfpI family
LEPMCGDO_02264 8.94e-120 yfbM - - K - - - FR47-like protein
LEPMCGDO_02265 8.35e-199 - - - EG - - - EamA-like transporter family
LEPMCGDO_02266 0.0 fusA1 - - J - - - elongation factor G
LEPMCGDO_02267 3.85e-151 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEPMCGDO_02268 1.67e-220 - - - K - - - WYL domain
LEPMCGDO_02269 1.25e-164 - - - F - - - glutamine amidotransferase
LEPMCGDO_02270 1.65e-106 - - - S - - - ASCH
LEPMCGDO_02271 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
LEPMCGDO_02272 2.79e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LEPMCGDO_02273 0.0 - - - S - - - Putative threonine/serine exporter
LEPMCGDO_02274 1.54e-248 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEPMCGDO_02275 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LEPMCGDO_02276 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
LEPMCGDO_02277 5.07e-157 ydgI - - C - - - Nitroreductase family
LEPMCGDO_02278 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LEPMCGDO_02279 4.06e-211 - - - S - - - KR domain
LEPMCGDO_02280 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEPMCGDO_02281 2.49e-95 - - - C - - - FMN binding
LEPMCGDO_02282 1.46e-204 - - - K - - - LysR family
LEPMCGDO_02283 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LEPMCGDO_02284 0.0 - - - C - - - FMN_bind
LEPMCGDO_02285 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
LEPMCGDO_02286 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LEPMCGDO_02287 1.91e-156 pnb - - C - - - nitroreductase
LEPMCGDO_02288 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
LEPMCGDO_02289 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LEPMCGDO_02290 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
LEPMCGDO_02291 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
LEPMCGDO_02292 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEPMCGDO_02293 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LEPMCGDO_02294 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LEPMCGDO_02295 3.54e-195 yycI - - S - - - YycH protein
LEPMCGDO_02296 3.55e-313 yycH - - S - - - YycH protein
LEPMCGDO_02297 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEPMCGDO_02298 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LEPMCGDO_02300 9.46e-44 - - - - - - - -
LEPMCGDO_02301 1.72e-40 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LEPMCGDO_02302 6.45e-70 - - - - - - - -
LEPMCGDO_02303 2.58e-52 - - - S - - - Phage gp6-like head-tail connector protein
LEPMCGDO_02306 1.25e-264 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LEPMCGDO_02307 3.04e-256 - - - S - - - Phage portal protein
LEPMCGDO_02309 0.0 terL - - S - - - overlaps another CDS with the same product name
LEPMCGDO_02310 2.13e-106 - - - L - - - overlaps another CDS with the same product name
LEPMCGDO_02311 4.46e-90 - - - L - - - HNH endonuclease
LEPMCGDO_02312 1.79e-68 - - - S - - - Head-tail joining protein
LEPMCGDO_02314 1.29e-96 - - - - - - - -
LEPMCGDO_02315 0.0 - - - S - - - Virulence-associated protein E
LEPMCGDO_02316 4.95e-177 - - - L - - - DNA replication protein
LEPMCGDO_02319 4.64e-12 - - - - - - - -
LEPMCGDO_02321 1.1e-06 - - - K ko:K07727 - ko00000,ko03000 transcriptional regulator
LEPMCGDO_02322 2.85e-290 sip - - L - - - Belongs to the 'phage' integrase family
LEPMCGDO_02323 2.54e-50 - - - - - - - -
LEPMCGDO_02324 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
LEPMCGDO_02325 1.08e-102 - - - S - - - Pyridoxamine 5'-phosphate oxidase
LEPMCGDO_02326 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
LEPMCGDO_02327 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LEPMCGDO_02328 3.41e-183 - - - S - - - haloacid dehalogenase-like hydrolase
LEPMCGDO_02330 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LEPMCGDO_02331 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEPMCGDO_02332 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEPMCGDO_02333 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LEPMCGDO_02334 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEPMCGDO_02335 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEPMCGDO_02337 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_02339 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEPMCGDO_02340 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEPMCGDO_02341 5.79e-288 yttB - - EGP - - - Major Facilitator
LEPMCGDO_02342 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LEPMCGDO_02343 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LEPMCGDO_02344 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LEPMCGDO_02345 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEPMCGDO_02346 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEPMCGDO_02347 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LEPMCGDO_02348 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEPMCGDO_02349 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEPMCGDO_02350 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEPMCGDO_02351 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LEPMCGDO_02352 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEPMCGDO_02353 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEPMCGDO_02354 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEPMCGDO_02355 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEPMCGDO_02356 9.21e-172 jag - - S ko:K06346 - ko00000 R3H domain protein
LEPMCGDO_02357 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEPMCGDO_02358 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEPMCGDO_02359 1.31e-143 - - - S - - - Cell surface protein
LEPMCGDO_02360 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
LEPMCGDO_02362 0.0 - - - - - - - -
LEPMCGDO_02363 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LEPMCGDO_02365 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LEPMCGDO_02366 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
LEPMCGDO_02367 4.02e-203 degV1 - - S - - - DegV family
LEPMCGDO_02368 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
LEPMCGDO_02369 3.12e-180 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
LEPMCGDO_02370 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LEPMCGDO_02371 7.43e-130 padR - - K - - - Virulence activator alpha C-term
LEPMCGDO_02372 2.51e-103 - - - T - - - Universal stress protein family
LEPMCGDO_02373 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LEPMCGDO_02374 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LEPMCGDO_02375 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEPMCGDO_02376 7.09e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEPMCGDO_02377 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
LEPMCGDO_02378 6.33e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
LEPMCGDO_02379 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LEPMCGDO_02380 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LEPMCGDO_02381 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LEPMCGDO_02382 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
LEPMCGDO_02383 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LEPMCGDO_02384 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LEPMCGDO_02385 6.02e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LEPMCGDO_02386 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_02387 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LEPMCGDO_02388 1.64e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
LEPMCGDO_02389 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
LEPMCGDO_02390 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_02391 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_02392 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
LEPMCGDO_02393 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
LEPMCGDO_02394 1.71e-139 ypcB - - S - - - integral membrane protein
LEPMCGDO_02395 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEPMCGDO_02396 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LEPMCGDO_02397 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LEPMCGDO_02398 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEPMCGDO_02399 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
LEPMCGDO_02400 1.54e-247 - - - K - - - Transcriptional regulator
LEPMCGDO_02401 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
LEPMCGDO_02402 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
LEPMCGDO_02403 1.99e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
LEPMCGDO_02404 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02405 3e-185 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
LEPMCGDO_02406 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LEPMCGDO_02407 4.71e-119 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LEPMCGDO_02408 1.88e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LEPMCGDO_02409 5.39e-228 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
LEPMCGDO_02410 5.31e-82 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LEPMCGDO_02411 2.88e-153 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
LEPMCGDO_02412 1.44e-228 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
LEPMCGDO_02413 1.6e-220 - - - C - - - Alcohol dehydrogenase GroES-like domain
LEPMCGDO_02414 7.45e-108 - - - S - - - Haem-degrading
LEPMCGDO_02415 1.87e-246 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LEPMCGDO_02416 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEPMCGDO_02417 6.56e-252 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LEPMCGDO_02418 3.39e-226 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEPMCGDO_02419 2.4e-258 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEPMCGDO_02420 5.84e-252 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LEPMCGDO_02421 0.0 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEPMCGDO_02422 4.32e-174 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
LEPMCGDO_02424 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LEPMCGDO_02425 2.47e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_02426 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPMCGDO_02427 1.28e-180 - - - K - - - DeoR C terminal sensor domain
LEPMCGDO_02428 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
LEPMCGDO_02429 1.63e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
LEPMCGDO_02430 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEPMCGDO_02431 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LEPMCGDO_02432 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
LEPMCGDO_02433 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LEPMCGDO_02434 1.59e-40 - - - S - - - Membrane
LEPMCGDO_02435 4.67e-108 - - - S - - - Membrane
LEPMCGDO_02436 1.65e-93 yueI - - S - - - Protein of unknown function (DUF1694)
LEPMCGDO_02437 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_02438 5.03e-95 - - - K - - - Transcriptional regulator
LEPMCGDO_02439 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_02440 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LEPMCGDO_02442 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
LEPMCGDO_02443 1.38e-123 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
LEPMCGDO_02444 3.82e-24 - - - - - - - -
LEPMCGDO_02445 7.01e-286 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LEPMCGDO_02446 3.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LEPMCGDO_02447 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
LEPMCGDO_02448 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
LEPMCGDO_02449 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
LEPMCGDO_02450 1.06e-16 - - - - - - - -
LEPMCGDO_02451 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
LEPMCGDO_02452 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
LEPMCGDO_02453 5.84e-294 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
LEPMCGDO_02454 1.82e-160 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEPMCGDO_02455 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LEPMCGDO_02456 2.93e-200 nanK - - GK - - - ROK family
LEPMCGDO_02457 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
LEPMCGDO_02458 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEPMCGDO_02459 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEPMCGDO_02460 3.89e-205 - - - I - - - alpha/beta hydrolase fold
LEPMCGDO_02461 2.54e-210 - - - I - - - alpha/beta hydrolase fold
LEPMCGDO_02462 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
LEPMCGDO_02463 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
LEPMCGDO_02464 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_02465 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEPMCGDO_02466 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
LEPMCGDO_02467 8.71e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LEPMCGDO_02468 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LEPMCGDO_02469 3.95e-132 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LEPMCGDO_02470 1.73e-93 - - - S - - - Protein of unknown function (DUF1694)
LEPMCGDO_02471 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LEPMCGDO_02472 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
LEPMCGDO_02473 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPMCGDO_02474 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_02475 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LEPMCGDO_02476 7.47e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
LEPMCGDO_02477 1.54e-310 - - - K ko:K02538 - ko00000,ko03000 PRD domain
LEPMCGDO_02478 2.28e-08 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPMCGDO_02479 1.91e-98 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPMCGDO_02480 6.25e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_02481 3.64e-224 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
LEPMCGDO_02482 4.66e-164 alsE - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
LEPMCGDO_02483 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEPMCGDO_02484 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEPMCGDO_02485 2.58e-186 yxeH - - S - - - hydrolase
LEPMCGDO_02486 2.83e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEPMCGDO_02488 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
LEPMCGDO_02489 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LEPMCGDO_02490 3.1e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
LEPMCGDO_02491 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LEPMCGDO_02492 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LEPMCGDO_02493 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_02494 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02495 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02496 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LEPMCGDO_02497 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEPMCGDO_02498 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02499 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LEPMCGDO_02500 6.87e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
LEPMCGDO_02501 1.25e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEPMCGDO_02502 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_02503 5.44e-174 - - - K - - - UTRA domain
LEPMCGDO_02504 3.59e-198 estA - - S - - - Putative esterase
LEPMCGDO_02505 2.09e-83 - - - - - - - -
LEPMCGDO_02506 2.25e-262 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_02507 4.06e-214 - - - K - - - Transcriptional regulator, LysR family
LEPMCGDO_02508 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
LEPMCGDO_02509 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LEPMCGDO_02510 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEPMCGDO_02511 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEPMCGDO_02512 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
LEPMCGDO_02513 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
LEPMCGDO_02514 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEPMCGDO_02515 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEPMCGDO_02516 4.42e-222 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEPMCGDO_02517 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LEPMCGDO_02518 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
LEPMCGDO_02519 2.1e-247 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LEPMCGDO_02520 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_02521 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LEPMCGDO_02522 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LEPMCGDO_02523 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LEPMCGDO_02524 7.8e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
LEPMCGDO_02525 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
LEPMCGDO_02526 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEPMCGDO_02527 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LEPMCGDO_02528 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LEPMCGDO_02529 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_02530 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LEPMCGDO_02531 1.94e-130 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LEPMCGDO_02532 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
LEPMCGDO_02533 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
LEPMCGDO_02534 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
LEPMCGDO_02535 2.13e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
LEPMCGDO_02536 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
LEPMCGDO_02537 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LEPMCGDO_02538 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LEPMCGDO_02539 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LEPMCGDO_02540 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LEPMCGDO_02541 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
LEPMCGDO_02542 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LEPMCGDO_02543 4.03e-283 - - - S - - - associated with various cellular activities
LEPMCGDO_02544 0.0 - - - S - - - Putative metallopeptidase domain
LEPMCGDO_02545 1.03e-65 - - - - - - - -
LEPMCGDO_02546 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
LEPMCGDO_02547 7.83e-60 - - - - - - - -
LEPMCGDO_02548 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_02549 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
LEPMCGDO_02550 1.83e-235 - - - S - - - Cell surface protein
LEPMCGDO_02551 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LEPMCGDO_02552 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LEPMCGDO_02553 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEPMCGDO_02556 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LEPMCGDO_02557 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
LEPMCGDO_02561 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
LEPMCGDO_02562 1.38e-71 - - - S - - - Cupin domain
LEPMCGDO_02563 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
LEPMCGDO_02564 8.81e-245 ysdE - - P - - - Citrate transporter
LEPMCGDO_02565 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LEPMCGDO_02566 1.53e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEPMCGDO_02567 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEPMCGDO_02568 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LEPMCGDO_02569 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LEPMCGDO_02570 2.69e-188 - - - KT - - - helix_turn_helix, mercury resistance
LEPMCGDO_02571 9.55e-08 - - - L ko:K07487 - ko00000 Transposase
LEPMCGDO_02572 2.16e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LEPMCGDO_02573 4.29e-101 - - - - - - - -
LEPMCGDO_02574 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LEPMCGDO_02575 6.3e-110 - - - FG - - - HIT domain
LEPMCGDO_02576 7.39e-224 ydhF - - S - - - Aldo keto reductase
LEPMCGDO_02577 8.93e-71 - - - S - - - Pfam:DUF59
LEPMCGDO_02578 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEPMCGDO_02579 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LEPMCGDO_02580 1.87e-249 - - - V - - - Beta-lactamase
LEPMCGDO_02581 2.16e-124 - - - V - - - VanZ like family
LEPMCGDO_02582 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
LEPMCGDO_02583 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
LEPMCGDO_02584 9.01e-155 - - - S - - - Membrane
LEPMCGDO_02585 1.14e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEPMCGDO_02586 3.55e-127 ywjB - - H - - - RibD C-terminal domain
LEPMCGDO_02587 5.72e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
LEPMCGDO_02588 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
LEPMCGDO_02589 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02590 2.7e-237 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LEPMCGDO_02591 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LEPMCGDO_02592 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEPMCGDO_02593 1.03e-48 - - - - - - - -
LEPMCGDO_02594 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LEPMCGDO_02595 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEPMCGDO_02596 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEPMCGDO_02597 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEPMCGDO_02598 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LEPMCGDO_02599 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEPMCGDO_02600 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
LEPMCGDO_02601 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LEPMCGDO_02603 7.72e-57 yabO - - J - - - S4 domain protein
LEPMCGDO_02604 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LEPMCGDO_02605 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEPMCGDO_02606 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEPMCGDO_02607 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LEPMCGDO_02608 0.0 - - - S - - - Putative peptidoglycan binding domain
LEPMCGDO_02609 4.87e-148 - - - S - - - (CBS) domain
LEPMCGDO_02610 1.3e-110 queT - - S - - - QueT transporter
LEPMCGDO_02611 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEPMCGDO_02612 7.73e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
LEPMCGDO_02613 7.9e-165 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LEPMCGDO_02614 1.38e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEPMCGDO_02615 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEPMCGDO_02616 3.04e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LEPMCGDO_02617 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LEPMCGDO_02618 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LEPMCGDO_02619 3.03e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEPMCGDO_02620 1.37e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
LEPMCGDO_02621 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LEPMCGDO_02622 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LEPMCGDO_02623 1.43e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEPMCGDO_02624 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEPMCGDO_02625 3.82e-230 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LEPMCGDO_02628 1.68e-24 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
LEPMCGDO_02629 1e-53 - - - G - - - Acyltransferase family
LEPMCGDO_02630 5.88e-130 - - - S - - - Polysaccharide biosynthesis protein
LEPMCGDO_02631 1.82e-39 cotSA - - M ko:K06338 - ko00000 Spore coat protein
LEPMCGDO_02632 1.9e-27 - - - - - - - -
LEPMCGDO_02633 1.15e-66 - - - S - - - Glycosyl transferase family 2
LEPMCGDO_02634 1.23e-135 - - - M - - - Glycosyltransferase Family 4
LEPMCGDO_02635 3.26e-236 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
LEPMCGDO_02636 5.76e-193 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
LEPMCGDO_02637 8.61e-111 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LEPMCGDO_02638 4.78e-165 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LEPMCGDO_02639 3.93e-162 ywqD - - D - - - Capsular exopolysaccharide family
LEPMCGDO_02640 9.42e-161 epsB - - M - - - biosynthesis protein
LEPMCGDO_02641 9.04e-179 - - - - - - - -
LEPMCGDO_02643 1.48e-163 - - - - - - - -
LEPMCGDO_02644 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEPMCGDO_02645 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEPMCGDO_02646 1.84e-189 - - - - - - - -
LEPMCGDO_02647 4.58e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LEPMCGDO_02648 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
LEPMCGDO_02649 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LEPMCGDO_02650 1.49e-273 - - - J - - - translation release factor activity
LEPMCGDO_02651 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LEPMCGDO_02652 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEPMCGDO_02653 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEPMCGDO_02654 4.01e-36 - - - - - - - -
LEPMCGDO_02655 2.69e-169 - - - S - - - YheO-like PAS domain
LEPMCGDO_02656 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEPMCGDO_02657 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LEPMCGDO_02658 1.32e-289 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
LEPMCGDO_02659 1.08e-307 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEPMCGDO_02660 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEPMCGDO_02661 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEPMCGDO_02662 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
LEPMCGDO_02663 2.46e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
LEPMCGDO_02664 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
LEPMCGDO_02665 1.45e-191 yxeH - - S - - - hydrolase
LEPMCGDO_02666 4.31e-179 - - - - - - - -
LEPMCGDO_02667 2.82e-236 - - - S - - - DUF218 domain
LEPMCGDO_02668 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEPMCGDO_02669 1.57e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LEPMCGDO_02670 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEPMCGDO_02671 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LEPMCGDO_02672 5.25e-168 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LEPMCGDO_02673 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEPMCGDO_02674 3.15e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
LEPMCGDO_02675 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEPMCGDO_02676 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
LEPMCGDO_02677 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEPMCGDO_02678 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEPMCGDO_02679 6.64e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LEPMCGDO_02680 1.81e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
LEPMCGDO_02681 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEPMCGDO_02682 6.59e-92 - - - F - - - DNA mismatch repair protein MutT
LEPMCGDO_02683 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
LEPMCGDO_02684 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
LEPMCGDO_02685 4.65e-229 - - - - - - - -
LEPMCGDO_02686 5.59e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LEPMCGDO_02687 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LEPMCGDO_02688 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
LEPMCGDO_02689 1.23e-262 - - - - - - - -
LEPMCGDO_02690 7.22e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEPMCGDO_02691 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
LEPMCGDO_02692 6.97e-209 - - - GK - - - ROK family
LEPMCGDO_02693 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02694 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_02695 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
LEPMCGDO_02696 9.68e-34 - - - - - - - -
LEPMCGDO_02697 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_02698 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
LEPMCGDO_02699 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LEPMCGDO_02700 3.54e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
LEPMCGDO_02701 0.0 - - - L - - - DNA helicase
LEPMCGDO_02702 1.85e-40 - - - - - - - -
LEPMCGDO_02703 3.9e-146 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_02704 2.52e-141 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_02705 2.3e-151 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_02706 8.7e-139 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_02707 2.88e-307 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LEPMCGDO_02708 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LEPMCGDO_02709 8.94e-15 - - - - - - - -
LEPMCGDO_02710 1.93e-31 plnF - - - - - - -
LEPMCGDO_02711 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_02712 1.44e-171 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LEPMCGDO_02713 5.61e-169 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LEPMCGDO_02714 4.78e-291 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LEPMCGDO_02715 1.9e-25 plnA - - - - - - -
LEPMCGDO_02716 1.22e-36 - - - - - - - -
LEPMCGDO_02717 2.08e-160 plnP - - S - - - CAAX protease self-immunity
LEPMCGDO_02718 5.58e-291 - - - M - - - Glycosyl transferase family 2
LEPMCGDO_02720 4.08e-39 - - - - - - - -
LEPMCGDO_02721 8.53e-34 plnJ - - - - - - -
LEPMCGDO_02722 3.29e-32 plnK - - - - - - -
LEPMCGDO_02723 9.76e-153 - - - - - - - -
LEPMCGDO_02724 6.24e-25 plnR - - - - - - -
LEPMCGDO_02725 1.15e-43 - - - - - - - -
LEPMCGDO_02726 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEPMCGDO_02727 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LEPMCGDO_02728 8.38e-192 - - - S - - - hydrolase
LEPMCGDO_02729 2.35e-212 - - - K - - - Transcriptional regulator
LEPMCGDO_02730 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_02731 4.32e-260 - - - EGP - - - Transporter, major facilitator family protein
LEPMCGDO_02732 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LEPMCGDO_02734 3.27e-81 - - - - - - - -
LEPMCGDO_02735 1.15e-39 - - - - - - - -
LEPMCGDO_02737 4.06e-47 - - - - - - - -
LEPMCGDO_02738 1.58e-144 - - - L - - - Transposase and inactivated derivatives, IS30 family
LEPMCGDO_02741 4.05e-89 - - - S - - - Immunity protein 63
LEPMCGDO_02742 2.99e-49 - - - - - - - -
LEPMCGDO_02744 7.42e-71 - - - M - - - nuclease activity
LEPMCGDO_02745 7.13e-54 - - - - - - - -
LEPMCGDO_02746 1.36e-33 - - - - - - - -
LEPMCGDO_02747 5.22e-68 - - - - - - - -
LEPMCGDO_02748 4.16e-80 - - - L - - - Participates in initiation and elongation during chromosome replication
LEPMCGDO_02749 6.38e-70 - - - - - - - -
LEPMCGDO_02753 8.33e-104 - - - - - - - -
LEPMCGDO_02755 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEPMCGDO_02756 4.09e-89 - - - - - - - -
LEPMCGDO_02757 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
LEPMCGDO_02758 2.84e-73 ytpP - - CO - - - Thioredoxin
LEPMCGDO_02759 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
LEPMCGDO_02760 3.89e-62 - - - - - - - -
LEPMCGDO_02761 2.38e-73 - - - - - - - -
LEPMCGDO_02762 2.32e-104 - - - S - - - Protein of unknown function (DUF2798)
LEPMCGDO_02763 4.05e-98 - - - - - - - -
LEPMCGDO_02764 4.15e-78 - - - - - - - -
LEPMCGDO_02765 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LEPMCGDO_02766 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
LEPMCGDO_02767 1.02e-102 uspA3 - - T - - - universal stress protein
LEPMCGDO_02768 8.36e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LEPMCGDO_02769 2.73e-24 - - - - - - - -
LEPMCGDO_02770 1.09e-55 - - - S - - - zinc-ribbon domain
LEPMCGDO_02771 9.66e-97 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LEPMCGDO_02772 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
LEPMCGDO_02773 3.96e-30 - - - S - - - Protein of unknown function (DUF2929)
LEPMCGDO_02774 1.85e-285 - - - M - - - Glycosyl transferases group 1
LEPMCGDO_02775 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LEPMCGDO_02776 2.63e-205 - - - S - - - Putative esterase
LEPMCGDO_02777 3.53e-169 - - - K - - - Transcriptional regulator
LEPMCGDO_02778 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEPMCGDO_02779 1.18e-176 - - - - - - - -
LEPMCGDO_02780 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPMCGDO_02781 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
LEPMCGDO_02782 2.41e-118 - - - K - - - Domain of unknown function (DUF1836)
LEPMCGDO_02783 1.55e-79 - - - - - - - -
LEPMCGDO_02784 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LEPMCGDO_02785 2.97e-76 - - - - - - - -
LEPMCGDO_02786 0.0 yhdP - - S - - - Transporter associated domain
LEPMCGDO_02787 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
LEPMCGDO_02788 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
LEPMCGDO_02789 3.36e-270 yttB - - EGP - - - Major Facilitator
LEPMCGDO_02790 8.13e-82 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_02791 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
LEPMCGDO_02792 4.71e-74 - - - S - - - SdpI/YhfL protein family
LEPMCGDO_02793 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEPMCGDO_02794 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
LEPMCGDO_02795 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEPMCGDO_02796 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEPMCGDO_02797 3.59e-26 - - - - - - - -
LEPMCGDO_02798 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
LEPMCGDO_02799 5.73e-208 mleR - - K - - - LysR family
LEPMCGDO_02800 7.47e-148 - - - GM - - - NAD(P)H-binding
LEPMCGDO_02801 1.57e-123 - - - K - - - Acetyltransferase (GNAT) family
LEPMCGDO_02802 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LEPMCGDO_02803 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEPMCGDO_02804 9.44e-219 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
LEPMCGDO_02805 1.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEPMCGDO_02806 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEPMCGDO_02807 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEPMCGDO_02808 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LEPMCGDO_02809 3.92e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LEPMCGDO_02810 7.96e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEPMCGDO_02811 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LEPMCGDO_02812 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEPMCGDO_02813 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
LEPMCGDO_02814 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LEPMCGDO_02815 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
LEPMCGDO_02816 2.24e-206 - - - GM - - - NmrA-like family
LEPMCGDO_02817 1.25e-199 - - - T - - - EAL domain
LEPMCGDO_02818 2.62e-121 - - - - - - - -
LEPMCGDO_02819 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
LEPMCGDO_02820 4.17e-163 - - - E - - - Methionine synthase
LEPMCGDO_02821 6.66e-281 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LEPMCGDO_02822 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LEPMCGDO_02823 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEPMCGDO_02824 5.35e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LEPMCGDO_02825 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEPMCGDO_02826 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPMCGDO_02827 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPMCGDO_02828 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPMCGDO_02829 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LEPMCGDO_02830 1e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEPMCGDO_02831 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEPMCGDO_02832 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LEPMCGDO_02833 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
LEPMCGDO_02834 3.23e-224 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
LEPMCGDO_02835 2.49e-190 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LEPMCGDO_02836 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
LEPMCGDO_02837 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_02838 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
LEPMCGDO_02839 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02840 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LEPMCGDO_02841 4.76e-56 - - - - - - - -
LEPMCGDO_02842 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
LEPMCGDO_02843 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02844 3.41e-190 - - - - - - - -
LEPMCGDO_02845 7.73e-104 usp5 - - T - - - universal stress protein
LEPMCGDO_02846 1.08e-47 - - - - - - - -
LEPMCGDO_02847 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
LEPMCGDO_02848 1.76e-114 - - - - - - - -
LEPMCGDO_02849 4.87e-66 - - - - - - - -
LEPMCGDO_02850 4.79e-13 - - - - - - - -
LEPMCGDO_02851 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LEPMCGDO_02852 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
LEPMCGDO_02853 1.52e-151 - - - - - - - -
LEPMCGDO_02854 1.21e-69 - - - - - - - -
LEPMCGDO_02856 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LEPMCGDO_02857 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LEPMCGDO_02858 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LEPMCGDO_02859 2.96e-41 - - - S - - - Pentapeptide repeats (8 copies)
LEPMCGDO_02860 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LEPMCGDO_02861 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LEPMCGDO_02862 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
LEPMCGDO_02863 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LEPMCGDO_02864 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
LEPMCGDO_02865 3.48e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LEPMCGDO_02866 4.43e-294 - - - S - - - Sterol carrier protein domain
LEPMCGDO_02867 1.33e-157 - - - EGP - - - Transmembrane secretion effector
LEPMCGDO_02868 1.25e-115 - - - EGP - - - Transmembrane secretion effector
LEPMCGDO_02869 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
LEPMCGDO_02870 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEPMCGDO_02871 2.13e-152 - - - K - - - Transcriptional regulator
LEPMCGDO_02872 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LEPMCGDO_02873 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LEPMCGDO_02874 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LEPMCGDO_02875 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02876 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02877 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
LEPMCGDO_02878 1.31e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_02879 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
LEPMCGDO_02880 1.4e-181 epsV - - S - - - glycosyl transferase family 2
LEPMCGDO_02881 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
LEPMCGDO_02882 7.63e-107 - - - - - - - -
LEPMCGDO_02883 5.06e-196 - - - S - - - hydrolase
LEPMCGDO_02884 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEPMCGDO_02885 2.8e-204 - - - EG - - - EamA-like transporter family
LEPMCGDO_02886 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LEPMCGDO_02887 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LEPMCGDO_02888 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
LEPMCGDO_02889 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
LEPMCGDO_02890 0.0 - - - M - - - Domain of unknown function (DUF5011)
LEPMCGDO_02891 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
LEPMCGDO_02892 4.3e-44 - - - - - - - -
LEPMCGDO_02893 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
LEPMCGDO_02894 0.0 ycaM - - E - - - amino acid
LEPMCGDO_02895 2.45e-101 - - - K - - - Winged helix DNA-binding domain
LEPMCGDO_02896 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
LEPMCGDO_02897 1.2e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LEPMCGDO_02898 1.3e-209 - - - K - - - Transcriptional regulator
LEPMCGDO_02900 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02901 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
LEPMCGDO_02902 2.03e-84 - - - - - - - -
LEPMCGDO_02903 3.2e-204 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LEPMCGDO_02904 1.72e-73 - - - - - - - -
LEPMCGDO_02905 1.24e-194 - - - K - - - Helix-turn-helix domain
LEPMCGDO_02906 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEPMCGDO_02907 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEPMCGDO_02908 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPMCGDO_02909 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEPMCGDO_02910 1.57e-237 - - - GM - - - Male sterility protein
LEPMCGDO_02911 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
LEPMCGDO_02912 4.61e-101 - - - M - - - LysM domain
LEPMCGDO_02913 3.03e-130 - - - M - - - Lysin motif
LEPMCGDO_02914 1.91e-136 - - - S - - - SdpI/YhfL protein family
LEPMCGDO_02915 1.58e-72 nudA - - S - - - ASCH
LEPMCGDO_02916 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LEPMCGDO_02917 2.06e-119 - - - - - - - -
LEPMCGDO_02918 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
LEPMCGDO_02919 3.55e-281 - - - T - - - diguanylate cyclase
LEPMCGDO_02920 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
LEPMCGDO_02921 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
LEPMCGDO_02922 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
LEPMCGDO_02923 3.05e-95 - - - - - - - -
LEPMCGDO_02924 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPMCGDO_02925 1.88e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
LEPMCGDO_02926 3.57e-150 - - - GM - - - NAD(P)H-binding
LEPMCGDO_02927 3.36e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LEPMCGDO_02928 6.7e-102 yphH - - S - - - Cupin domain
LEPMCGDO_02929 3.55e-79 - - - I - - - sulfurtransferase activity
LEPMCGDO_02930 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
LEPMCGDO_02931 8.38e-152 - - - GM - - - NAD(P)H-binding
LEPMCGDO_02932 2.31e-277 - - - - - - - -
LEPMCGDO_02933 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_02934 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LEPMCGDO_02935 1.3e-226 - - - O - - - protein import
LEPMCGDO_02936 3.23e-290 amd - - E - - - Peptidase family M20/M25/M40
LEPMCGDO_02937 2.96e-209 yhxD - - IQ - - - KR domain
LEPMCGDO_02939 1.39e-92 - - - - - - - -
LEPMCGDO_02940 5.2e-187 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_02941 0.0 - - - E - - - Amino Acid
LEPMCGDO_02942 1.67e-86 lysM - - M - - - LysM domain
LEPMCGDO_02943 6.97e-285 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
LEPMCGDO_02945 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEPMCGDO_02946 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEPMCGDO_02947 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEPMCGDO_02948 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LEPMCGDO_02949 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
LEPMCGDO_02950 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LEPMCGDO_02951 6.25e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LEPMCGDO_02952 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LEPMCGDO_02953 1.19e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEPMCGDO_02955 2.37e-199 - - - G - - - Peptidase_C39 like family
LEPMCGDO_02956 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LEPMCGDO_02957 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LEPMCGDO_02958 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LEPMCGDO_02959 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
LEPMCGDO_02960 0.0 levR - - K - - - Sigma-54 interaction domain
LEPMCGDO_02961 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LEPMCGDO_02962 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LEPMCGDO_02963 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEPMCGDO_02964 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
LEPMCGDO_02965 4.82e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
LEPMCGDO_02966 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEPMCGDO_02967 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
LEPMCGDO_02968 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LEPMCGDO_02969 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
LEPMCGDO_02970 6.04e-227 - - - EG - - - EamA-like transporter family
LEPMCGDO_02971 3.3e-166 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEPMCGDO_02972 4.57e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
LEPMCGDO_02973 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LEPMCGDO_02974 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEPMCGDO_02975 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LEPMCGDO_02976 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LEPMCGDO_02977 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEPMCGDO_02978 4.91e-265 yacL - - S - - - domain protein
LEPMCGDO_02979 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEPMCGDO_02980 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LEPMCGDO_02981 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEPMCGDO_02982 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEPMCGDO_02983 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
LEPMCGDO_02984 4.58e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
LEPMCGDO_02985 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LEPMCGDO_02986 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEPMCGDO_02987 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LEPMCGDO_02988 3.43e-203 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEPMCGDO_02989 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEPMCGDO_02990 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEPMCGDO_02991 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEPMCGDO_02992 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEPMCGDO_02994 8.95e-293 - - - L - - - Belongs to the 'phage' integrase family
LEPMCGDO_02996 5.36e-85 - - - S - - - Acyltransferase family
LEPMCGDO_02997 6.93e-96 - - - E - - - IrrE N-terminal-like domain
LEPMCGDO_02998 1.38e-82 - - - K - - - Helix-turn-helix XRE-family like proteins
LEPMCGDO_02999 2.57e-07 - - - K - - - Transcriptional
LEPMCGDO_03003 1.49e-126 - - - - - - - -
LEPMCGDO_03007 1.11e-107 - - - - - - - -
LEPMCGDO_03008 3.04e-155 - - - S - - - AAA domain
LEPMCGDO_03009 2.81e-156 - - - S - - - Protein of unknown function (DUF669)
LEPMCGDO_03010 4.66e-62 - - - L - - - DnaD domain protein
LEPMCGDO_03011 5.39e-66 - - - - - - - -
LEPMCGDO_03012 1.12e-55 - - - - - - - -
LEPMCGDO_03013 5.7e-87 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LEPMCGDO_03014 8.27e-14 - - - - - - - -
LEPMCGDO_03015 4.56e-39 - - - S - - - YopX protein
LEPMCGDO_03018 6.41e-106 - - - S - - - Phage transcriptional regulator, ArpU family
LEPMCGDO_03024 2.18e-20 - - - - - - - -
LEPMCGDO_03025 1.36e-65 - - - S - - - Terminase small subunit
LEPMCGDO_03026 1.27e-237 - - - S - - - Phage terminase, large subunit, PBSX family
LEPMCGDO_03027 2.67e-137 - - - S - - - Phage portal protein, SPP1 Gp6-like
LEPMCGDO_03028 3.32e-52 - - - S - - - Phage minor capsid protein 2
LEPMCGDO_03030 1.73e-135 - - - - - - - -
LEPMCGDO_03031 5.98e-06 - - - - - - - -
LEPMCGDO_03039 7.48e-168 - - - L - - - Phage tail tape measure protein TP901
LEPMCGDO_03041 5.71e-123 - - - S - - - Prophage endopeptidase tail
LEPMCGDO_03044 1.37e-256 - - - S - - - Domain of unknown function (DUF2479)
LEPMCGDO_03048 1.36e-239 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LEPMCGDO_03049 5.33e-63 - - - - - - - -
LEPMCGDO_03050 7.5e-58 - - - S - - - Bacteriophage holin
LEPMCGDO_03051 4.3e-35 - - - T ko:K07172 - ko00000,ko02048 SpoVT / AbrB like domain
LEPMCGDO_03052 5.6e-25 chpA - - T ko:K07171,ko:K18841 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LEPMCGDO_03053 5.84e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LEPMCGDO_03054 3.21e-84 - - - L - - - nuclease
LEPMCGDO_03055 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEPMCGDO_03056 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LEPMCGDO_03057 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEPMCGDO_03058 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEPMCGDO_03059 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LEPMCGDO_03060 9.52e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LEPMCGDO_03061 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEPMCGDO_03062 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEPMCGDO_03063 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEPMCGDO_03064 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEPMCGDO_03065 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
LEPMCGDO_03066 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEPMCGDO_03067 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
LEPMCGDO_03068 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LEPMCGDO_03069 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
LEPMCGDO_03070 1.53e-212 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEPMCGDO_03071 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LEPMCGDO_03072 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LEPMCGDO_03073 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
LEPMCGDO_03074 6.61e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
LEPMCGDO_03075 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_03076 1.53e-176 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
LEPMCGDO_03077 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LEPMCGDO_03078 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LEPMCGDO_03079 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LEPMCGDO_03080 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LEPMCGDO_03081 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEPMCGDO_03082 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEPMCGDO_03083 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
LEPMCGDO_03084 6.48e-142 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LEPMCGDO_03085 5.5e-05 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEPMCGDO_03086 7.98e-80 - - - M - - - Lysin motif
LEPMCGDO_03087 7.69e-94 - - - M - - - LysM domain protein
LEPMCGDO_03088 4.91e-87 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
LEPMCGDO_03089 9.03e-229 - - - - - - - -
LEPMCGDO_03090 9.77e-170 - - - - - - - -
LEPMCGDO_03091 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
LEPMCGDO_03092 2.03e-75 - - - - - - - -
LEPMCGDO_03093 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEPMCGDO_03094 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
LEPMCGDO_03095 1.24e-99 - - - K - - - Transcriptional regulator
LEPMCGDO_03096 1.17e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LEPMCGDO_03097 1.21e-50 - - - - - - - -
LEPMCGDO_03099 1.04e-35 - - - - - - - -
LEPMCGDO_03100 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
LEPMCGDO_03101 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_03102 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_03103 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LEPMCGDO_03104 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEPMCGDO_03105 3.68e-125 - - - K - - - Cupin domain
LEPMCGDO_03106 8.08e-110 - - - S - - - ASCH
LEPMCGDO_03107 1.88e-111 - - - K - - - GNAT family
LEPMCGDO_03108 2.14e-117 - - - K - - - acetyltransferase
LEPMCGDO_03109 2.06e-30 - - - - - - - -
LEPMCGDO_03110 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LEPMCGDO_03111 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEPMCGDO_03112 1.08e-243 - - - - - - - -
LEPMCGDO_03113 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
LEPMCGDO_03114 1.16e-206 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LEPMCGDO_03116 6.77e-305 xylP1 - - G - - - MFS/sugar transport protein
LEPMCGDO_03117 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LEPMCGDO_03118 7.28e-42 - - - - - - - -
LEPMCGDO_03119 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LEPMCGDO_03120 6.4e-54 - - - - - - - -
LEPMCGDO_03121 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LEPMCGDO_03122 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEPMCGDO_03123 2.34e-80 - - - S - - - CHY zinc finger
LEPMCGDO_03124 9.4e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEPMCGDO_03125 1.1e-280 - - - - - - - -
LEPMCGDO_03126 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LEPMCGDO_03127 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEPMCGDO_03128 3.93e-59 - - - - - - - -
LEPMCGDO_03129 2.24e-112 - - - K - - - Transcriptional regulator PadR-like family
LEPMCGDO_03130 0.0 - - - P - - - Major Facilitator Superfamily
LEPMCGDO_03131 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LEPMCGDO_03132 5.43e-228 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LEPMCGDO_03133 8.95e-60 - - - - - - - -
LEPMCGDO_03134 4.27e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
LEPMCGDO_03135 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LEPMCGDO_03136 0.0 sufI - - Q - - - Multicopper oxidase
LEPMCGDO_03137 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LEPMCGDO_03138 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LEPMCGDO_03139 1.96e-295 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LEPMCGDO_03140 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
LEPMCGDO_03141 2.16e-103 - - - - - - - -
LEPMCGDO_03142 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEPMCGDO_03143 8.62e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
LEPMCGDO_03144 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)