ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HNAHMFAC_00002 5.67e-149 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HNAHMFAC_00003 9.33e-106 - - - S - - - Domain of unknown function (DUF4767)
HNAHMFAC_00004 1.25e-271 - - - - - - - -
HNAHMFAC_00005 4e-156 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HNAHMFAC_00006 1.86e-210 - - - - - - - -
HNAHMFAC_00007 1.36e-70 - - - K - - - DNA-templated transcription, initiation
HNAHMFAC_00008 1.17e-209 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HNAHMFAC_00009 6.2e-170 epsB - - M - - - biosynthesis protein
HNAHMFAC_00010 1.19e-157 ywqD - - D - - - Capsular exopolysaccharide family
HNAHMFAC_00011 8.95e-175 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HNAHMFAC_00012 1.56e-152 epsE2 - - M - - - Bacterial sugar transferase
HNAHMFAC_00013 1.21e-108 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
HNAHMFAC_00014 7.03e-89 - - - S - - - Glycosyltransferase family 28 C-terminal domain
HNAHMFAC_00015 2.52e-153 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HNAHMFAC_00016 7.65e-189 - - - H - - - Glycosyl transferase family 11
HNAHMFAC_00017 8.52e-148 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
HNAHMFAC_00018 4.38e-193 - - - M - - - Glycosyl transferases group 1
HNAHMFAC_00019 3.79e-104 - - - M - - - Glycosyl transferase family 2
HNAHMFAC_00020 8.21e-268 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HNAHMFAC_00021 1.49e-68 - - - S - - - glycosyl transferase family 2
HNAHMFAC_00022 6.88e-31 - - - - - - - -
HNAHMFAC_00023 1.32e-272 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
HNAHMFAC_00024 1.62e-213 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HNAHMFAC_00026 1.42e-36 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNAHMFAC_00028 7.17e-32 - - - UW - - - Tetratricopeptide repeat
HNAHMFAC_00029 3.21e-211 - - - S - - - glycosyl transferase family 2
HNAHMFAC_00030 5.61e-253 - - - M - - - transferase activity, transferring glycosyl groups
HNAHMFAC_00031 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HNAHMFAC_00032 2.75e-245 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HNAHMFAC_00033 6.34e-132 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HNAHMFAC_00034 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNAHMFAC_00035 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNAHMFAC_00036 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HNAHMFAC_00037 5.57e-104 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNAHMFAC_00038 1.39e-180 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNAHMFAC_00039 3.08e-115 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
HNAHMFAC_00040 5.9e-46 - - - - - - - -
HNAHMFAC_00041 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HNAHMFAC_00042 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNAHMFAC_00043 1.18e-291 - - - G - - - Major Facilitator Superfamily
HNAHMFAC_00044 3.46e-242 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HNAHMFAC_00045 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HNAHMFAC_00046 8.06e-17 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HNAHMFAC_00047 5.22e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HNAHMFAC_00048 1.89e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNAHMFAC_00049 2.48e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNAHMFAC_00050 1.96e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00051 2.23e-150 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
HNAHMFAC_00052 9.43e-187 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00053 1.78e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNAHMFAC_00054 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNAHMFAC_00055 1.9e-182 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
HNAHMFAC_00056 3.25e-44 - - - - - - - -
HNAHMFAC_00057 3.07e-142 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HNAHMFAC_00058 1.65e-31 - - - - - - - -
HNAHMFAC_00059 1.68e-109 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNAHMFAC_00060 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNAHMFAC_00061 5.45e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNAHMFAC_00062 2.53e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNAHMFAC_00063 3.03e-44 - - - S - - - Protein of unknown function (DUF2508)
HNAHMFAC_00064 4.15e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNAHMFAC_00065 3.56e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
HNAHMFAC_00066 8.05e-197 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HNAHMFAC_00067 3.33e-78 yabA - - L - - - Involved in initiation control of chromosome replication
HNAHMFAC_00068 3.42e-198 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNAHMFAC_00069 3.16e-178 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HNAHMFAC_00070 2.13e-111 - - - S - - - ECF transporter, substrate-specific component
HNAHMFAC_00071 1.38e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HNAHMFAC_00072 2.62e-121 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HNAHMFAC_00073 2.03e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNAHMFAC_00074 1.11e-290 - - - D - - - nuclear chromosome segregation
HNAHMFAC_00075 5.22e-61 - - - - - - - -
HNAHMFAC_00076 1.92e-147 - - - - - - - -
HNAHMFAC_00077 5.74e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNAHMFAC_00078 9.69e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNAHMFAC_00079 1.81e-310 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNAHMFAC_00080 5.26e-88 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HNAHMFAC_00081 3.03e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_00082 1.19e-104 - - - - - - - -
HNAHMFAC_00083 9.69e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNAHMFAC_00084 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HNAHMFAC_00085 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNAHMFAC_00086 2.77e-133 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HNAHMFAC_00087 1.69e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HNAHMFAC_00088 5.72e-104 - - - K - - - LytTr DNA-binding domain
HNAHMFAC_00089 6.76e-168 - - - S - - - membrane
HNAHMFAC_00090 1.91e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HNAHMFAC_00091 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNAHMFAC_00092 2.27e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNAHMFAC_00093 3.38e-224 yvdE - - K - - - helix_turn _helix lactose operon repressor
HNAHMFAC_00094 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HNAHMFAC_00095 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HNAHMFAC_00096 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HNAHMFAC_00097 4.64e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HNAHMFAC_00098 1.36e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNAHMFAC_00099 2.1e-289 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNAHMFAC_00100 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNAHMFAC_00101 3.99e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00102 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
HNAHMFAC_00103 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HNAHMFAC_00104 2.37e-95 - - - S - - - Domain of unknown function (DUF1934)
HNAHMFAC_00105 1.03e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNAHMFAC_00106 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNAHMFAC_00107 1.47e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNAHMFAC_00108 1.87e-304 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HNAHMFAC_00109 3.36e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNAHMFAC_00110 1.98e-163 - - - K - - - Psort location CytoplasmicMembrane, score
HNAHMFAC_00111 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HNAHMFAC_00112 2.23e-69 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HNAHMFAC_00113 1.45e-236 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HNAHMFAC_00114 1.87e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNAHMFAC_00117 2.42e-35 - - - S - - - Domain of unknown function (DUF3173)
HNAHMFAC_00118 1.69e-44 - - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_00119 1.92e-198 - - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_00121 1.91e-144 - - - K - - - transcriptional regulator
HNAHMFAC_00122 2.85e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HNAHMFAC_00123 2.33e-25 - - - S - - - Domain of unknown function (DUF4393)
HNAHMFAC_00124 7.75e-94 - - - S - - - Pfam:Peptidase_M78
HNAHMFAC_00125 7.76e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
HNAHMFAC_00126 1.3e-40 - - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_00127 4.47e-176 - - - K ko:K07741 - ko00000 Phage antirepressor protein
HNAHMFAC_00130 1.94e-34 - - - - - - - -
HNAHMFAC_00133 7.02e-15 - - - - - - - -
HNAHMFAC_00134 2.15e-42 - - - - - - - -
HNAHMFAC_00135 7.26e-191 - - - S - - - Protein of unknown function (DUF1351)
HNAHMFAC_00136 1.32e-187 - - - S - - - ERF superfamily
HNAHMFAC_00137 4.18e-140 - - - L - - - Psort location Cytoplasmic, score
HNAHMFAC_00142 1.03e-05 - - - S - - - Pfam:DUF5406
HNAHMFAC_00145 2.37e-59 - - - L - - - Endodeoxyribonuclease RusA
HNAHMFAC_00146 1.98e-55 - - - - - - - -
HNAHMFAC_00152 7.45e-157 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
HNAHMFAC_00153 9.71e-232 - - - S - - - Terminase-like family
HNAHMFAC_00154 6.51e-213 - - - S - - - Phage portal protein, SPP1 Gp6-like
HNAHMFAC_00155 8.36e-110 - - - - - - - -
HNAHMFAC_00156 4.42e-38 - - - S - - - Domain of unknown function (DUF4355)
HNAHMFAC_00157 2.66e-110 - - - - - - - -
HNAHMFAC_00158 1.16e-21 - - - - - - - -
HNAHMFAC_00159 2.17e-40 - - - - - - - -
HNAHMFAC_00160 3.87e-64 - - - - - - - -
HNAHMFAC_00162 8.94e-30 - - - - - - - -
HNAHMFAC_00163 9.24e-130 - - - S - - - Protein of unknown function (DUF3383)
HNAHMFAC_00164 9.71e-48 - - - - - - - -
HNAHMFAC_00165 3.54e-06 - - - - - - - -
HNAHMFAC_00167 6.18e-43 - - - - - - - -
HNAHMFAC_00168 6.42e-69 - - - M - - - LysM domain
HNAHMFAC_00169 1.8e-46 - - - - - - - -
HNAHMFAC_00170 3.47e-113 - - - - - - - -
HNAHMFAC_00173 5.17e-150 - - - S - - - Baseplate J-like protein
HNAHMFAC_00174 1.67e-37 - - - - - - - -
HNAHMFAC_00175 7.29e-54 - - - S - - - Phage tail-collar fibre protein
HNAHMFAC_00178 2.8e-58 - - - LM - - - gp58-like protein
HNAHMFAC_00182 8.65e-33 - - - - - - - -
HNAHMFAC_00183 8.56e-05 - - - - - - - -
HNAHMFAC_00184 8.5e-33 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HNAHMFAC_00185 1.42e-195 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
HNAHMFAC_00186 4.78e-10 - - - - - - - -
HNAHMFAC_00189 1.49e-274 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HNAHMFAC_00190 3.74e-115 gtcA1 - - S - - - Teichoic acid glycosylation protein
HNAHMFAC_00191 1.36e-100 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HNAHMFAC_00192 1.21e-206 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HNAHMFAC_00193 1.64e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HNAHMFAC_00194 2.45e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HNAHMFAC_00195 1.19e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00196 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNAHMFAC_00197 3.2e-91 - - - O - - - OsmC-like protein
HNAHMFAC_00198 2.03e-158 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HNAHMFAC_00199 1.93e-145 - - - T - - - Region found in RelA / SpoT proteins
HNAHMFAC_00200 1.68e-148 dltr - - K - - - response regulator
HNAHMFAC_00201 4.3e-289 sptS - - T - - - Histidine kinase
HNAHMFAC_00202 9.33e-16 pspA - - S - - - dextransucrase activity
HNAHMFAC_00204 1.4e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_00206 3.86e-59 - - - - - - - -
HNAHMFAC_00209 1.51e-14 - - - L ko:K06993 - ko00000 Caulimovirus viroplasmin
HNAHMFAC_00210 3.94e-199 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
HNAHMFAC_00212 3.54e-205 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_00213 1.48e-172 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_00215 5.09e-41 - - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_00216 2.13e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_00217 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HNAHMFAC_00218 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HNAHMFAC_00219 2.29e-177 - - - S - - - haloacid dehalogenase-like hydrolase
HNAHMFAC_00221 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HNAHMFAC_00222 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNAHMFAC_00223 8.07e-91 - - - - - - - -
HNAHMFAC_00224 1.33e-137 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HNAHMFAC_00225 1.38e-183 - - - M - - - Glycosyl transferase family 2
HNAHMFAC_00226 6.99e-117 - - - S - - - Domain of unknown function (DUF4811)
HNAHMFAC_00227 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HNAHMFAC_00228 3.24e-102 - - - K - - - MerR HTH family regulatory protein
HNAHMFAC_00229 1.56e-258 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HNAHMFAC_00230 1.12e-25 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00231 3.39e-53 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00232 1.22e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
HNAHMFAC_00233 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HNAHMFAC_00236 9.69e-104 - - - M - - - Sortase family
HNAHMFAC_00237 2.08e-13 - - - GK - - - ROK family
HNAHMFAC_00238 2.8e-171 - - - GK - - - ROK family
HNAHMFAC_00239 1.93e-81 - - - K - - - AraC-like ligand binding domain
HNAHMFAC_00240 3e-75 - - - K - - - helix_turn_helix, arabinose operon control protein
HNAHMFAC_00241 7.32e-216 - - - I - - - Carboxylesterase family
HNAHMFAC_00242 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HNAHMFAC_00243 1.77e-157 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HNAHMFAC_00244 7.8e-107 - - - - - - - -
HNAHMFAC_00245 6.8e-187 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HNAHMFAC_00246 3.35e-119 - - - S - - - ECF-type riboflavin transporter, S component
HNAHMFAC_00247 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HNAHMFAC_00248 1.41e-77 - - - - - - - -
HNAHMFAC_00249 6.8e-17 - - - - - - - -
HNAHMFAC_00250 1.72e-265 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HNAHMFAC_00251 1.14e-193 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNAHMFAC_00252 2.13e-76 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HNAHMFAC_00253 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HNAHMFAC_00254 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HNAHMFAC_00255 1.57e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HNAHMFAC_00256 1.73e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNAHMFAC_00257 7.32e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HNAHMFAC_00258 1e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNAHMFAC_00259 6.38e-197 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNAHMFAC_00260 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNAHMFAC_00261 2.74e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNAHMFAC_00262 2.53e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HNAHMFAC_00263 5.29e-199 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HNAHMFAC_00264 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HNAHMFAC_00265 3.49e-63 - - - - - - - -
HNAHMFAC_00266 3.6e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HNAHMFAC_00267 3.3e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HNAHMFAC_00268 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNAHMFAC_00269 9.69e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNAHMFAC_00270 1.49e-308 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNAHMFAC_00271 1.29e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HNAHMFAC_00272 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HNAHMFAC_00273 2.16e-207 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNAHMFAC_00274 4.51e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HNAHMFAC_00275 9.07e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HNAHMFAC_00276 6.36e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HNAHMFAC_00277 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
HNAHMFAC_00278 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HNAHMFAC_00279 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNAHMFAC_00280 4.5e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNAHMFAC_00281 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNAHMFAC_00282 1.72e-244 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNAHMFAC_00283 8.34e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HNAHMFAC_00284 3.16e-232 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00285 1.84e-207 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNAHMFAC_00286 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00287 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00288 1.29e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNAHMFAC_00289 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HNAHMFAC_00290 1.36e-248 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNAHMFAC_00291 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HNAHMFAC_00292 3.48e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNAHMFAC_00293 1.15e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNAHMFAC_00294 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HNAHMFAC_00295 2.07e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNAHMFAC_00296 3.7e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HNAHMFAC_00297 2.61e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNAHMFAC_00298 2.63e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNAHMFAC_00299 2.61e-96 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
HNAHMFAC_00300 2.15e-151 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HNAHMFAC_00301 7.82e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNAHMFAC_00302 1.7e-45 ynzC - - S - - - UPF0291 protein
HNAHMFAC_00303 4.85e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HNAHMFAC_00304 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_00305 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_00306 2.99e-292 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HNAHMFAC_00307 1.16e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HNAHMFAC_00308 2.19e-249 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HNAHMFAC_00309 7.4e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HNAHMFAC_00310 8.74e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNAHMFAC_00311 1.18e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HNAHMFAC_00312 2.02e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNAHMFAC_00313 2.41e-175 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNAHMFAC_00314 3.37e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HNAHMFAC_00315 2.69e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HNAHMFAC_00316 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNAHMFAC_00317 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNAHMFAC_00318 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HNAHMFAC_00319 1.83e-279 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HNAHMFAC_00320 6.23e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HNAHMFAC_00321 1.32e-63 - - - J - - - ribosomal protein
HNAHMFAC_00322 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNAHMFAC_00323 4.75e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNAHMFAC_00324 4.94e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNAHMFAC_00325 4.11e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HNAHMFAC_00326 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HNAHMFAC_00327 1.03e-122 - - - S - - - GyrI-like small molecule binding domain
HNAHMFAC_00328 3.77e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNAHMFAC_00329 9.65e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNAHMFAC_00330 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HNAHMFAC_00331 1.73e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNAHMFAC_00332 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNAHMFAC_00333 5.42e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HNAHMFAC_00334 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HNAHMFAC_00335 5.93e-124 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNAHMFAC_00336 0.0 potE - - E - - - Amino Acid
HNAHMFAC_00337 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNAHMFAC_00338 5.29e-239 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNAHMFAC_00339 2.65e-123 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNAHMFAC_00340 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HNAHMFAC_00341 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HNAHMFAC_00342 9.46e-199 lysR5 - - K - - - LysR substrate binding domain
HNAHMFAC_00344 4.92e-130 - - - I - - - PAP2 superfamily
HNAHMFAC_00345 2.48e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNAHMFAC_00346 8.43e-42 - - - S - - - Sugar efflux transporter for intercellular exchange
HNAHMFAC_00347 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HNAHMFAC_00348 5.11e-241 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HNAHMFAC_00349 2e-64 - - - K - - - Helix-turn-helix domain
HNAHMFAC_00350 2.65e-185 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HNAHMFAC_00351 5.57e-93 - - - L - - - nuclease
HNAHMFAC_00352 1.1e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HNAHMFAC_00353 2.94e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNAHMFAC_00354 1.74e-117 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00355 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HNAHMFAC_00356 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HNAHMFAC_00357 4.93e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HNAHMFAC_00358 0.0 - - - S - - - Putative threonine/serine exporter
HNAHMFAC_00359 3.61e-244 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HNAHMFAC_00360 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HNAHMFAC_00361 0.0 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_00362 1.08e-38 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_00363 1.66e-100 - - - S - - - Psort location CytoplasmicMembrane, score
HNAHMFAC_00364 2.22e-264 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_00365 3.6e-112 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNAHMFAC_00366 5.81e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HNAHMFAC_00367 1.91e-85 - - - - - - - -
HNAHMFAC_00368 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNAHMFAC_00369 1.43e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNAHMFAC_00370 9.01e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HNAHMFAC_00371 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HNAHMFAC_00372 3.72e-282 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HNAHMFAC_00373 9.01e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HNAHMFAC_00374 3.28e-180 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HNAHMFAC_00375 3.65e-11 - - - - - - - -
HNAHMFAC_00376 4.45e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNAHMFAC_00377 2.23e-202 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNAHMFAC_00378 7.17e-154 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HNAHMFAC_00379 2.89e-194 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HNAHMFAC_00380 2.53e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
HNAHMFAC_00381 3.44e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNAHMFAC_00382 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HNAHMFAC_00383 5.18e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HNAHMFAC_00384 2.02e-221 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HNAHMFAC_00385 2.3e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNAHMFAC_00386 2.36e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNAHMFAC_00387 5.64e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HNAHMFAC_00388 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HNAHMFAC_00389 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HNAHMFAC_00390 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNAHMFAC_00391 3.52e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNAHMFAC_00393 6.97e-164 - - - - - - - -
HNAHMFAC_00394 1.35e-113 - - - - - - - -
HNAHMFAC_00396 2.31e-34 - - - M - - - domain protein
HNAHMFAC_00397 1.65e-89 - - - M - - - domain protein
HNAHMFAC_00399 1.62e-197 - - - S - - - DNA/RNA non-specific endonuclease
HNAHMFAC_00400 6.84e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HNAHMFAC_00401 7.1e-152 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00402 9.36e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00403 6.85e-193 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_00404 1.33e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HNAHMFAC_00405 1.35e-194 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNAHMFAC_00406 5.38e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HNAHMFAC_00407 4.24e-78 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HNAHMFAC_00408 6.31e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HNAHMFAC_00409 6.33e-187 - - - - - - - -
HNAHMFAC_00410 5.06e-176 - - - - - - - -
HNAHMFAC_00411 5.06e-31 - - - - - - - -
HNAHMFAC_00412 2.02e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HNAHMFAC_00413 2.21e-168 - - - - - - - -
HNAHMFAC_00414 2.18e-221 - - - - - - - -
HNAHMFAC_00415 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HNAHMFAC_00416 3.43e-66 ybjQ - - S - - - Belongs to the UPF0145 family
HNAHMFAC_00417 3.1e-227 - - - S - - - DUF218 domain
HNAHMFAC_00418 1.5e-189 yxeH - - S - - - hydrolase
HNAHMFAC_00419 0.0 - - - I - - - Protein of unknown function (DUF2974)
HNAHMFAC_00420 2.07e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNAHMFAC_00421 3.4e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNAHMFAC_00422 2.16e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNAHMFAC_00423 3.69e-120 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNAHMFAC_00424 2.04e-227 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HNAHMFAC_00425 2.8e-295 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNAHMFAC_00426 5.97e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HNAHMFAC_00427 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HNAHMFAC_00428 3.81e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNAHMFAC_00429 9.4e-138 pncA - - Q - - - Isochorismatase family
HNAHMFAC_00430 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNAHMFAC_00431 8.09e-260 - - - M - - - Glycosyl transferases group 1
HNAHMFAC_00432 1.24e-135 alkD - - L - - - DNA alkylation repair enzyme
HNAHMFAC_00433 8.09e-149 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00434 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00435 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HNAHMFAC_00436 1.63e-147 - - - C - - - nitroreductase
HNAHMFAC_00437 5.43e-212 - - - C - - - Oxidoreductase
HNAHMFAC_00438 2.08e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HNAHMFAC_00439 3.52e-15 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HNAHMFAC_00440 6.44e-184 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HNAHMFAC_00441 2.26e-216 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
HNAHMFAC_00442 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_00443 1.41e-171 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNAHMFAC_00444 9.17e-109 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNAHMFAC_00445 1.11e-262 - - - P - - - Major Facilitator Superfamily
HNAHMFAC_00446 1e-101 yfhC - - C - - - nitroreductase
HNAHMFAC_00447 0.0 - - - V - - - ABC transporter transmembrane region
HNAHMFAC_00448 5.61e-71 - - - - - - - -
HNAHMFAC_00449 8.69e-68 - - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
HNAHMFAC_00450 2.01e-57 - - - - ko:K07473 - ko00000,ko02048 -
HNAHMFAC_00451 1.34e-141 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HNAHMFAC_00452 1.4e-95 - - - - - - - -
HNAHMFAC_00453 6.61e-100 - - - - - - - -
HNAHMFAC_00454 7.84e-101 - - - K - - - Acetyltransferase (GNAT) domain
HNAHMFAC_00455 1.4e-109 - - - FG - - - HIT domain
HNAHMFAC_00456 8.41e-37 - - - S - - - MazG-like family
HNAHMFAC_00457 1.93e-12 - - - S - - - MazG-like family
HNAHMFAC_00458 1.55e-79 - - - - - - - -
HNAHMFAC_00459 3.34e-42 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HNAHMFAC_00460 7.1e-91 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HNAHMFAC_00461 9.36e-36 - - - - - - - -
HNAHMFAC_00462 4.66e-167 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HNAHMFAC_00463 1.72e-303 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HNAHMFAC_00464 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HNAHMFAC_00465 8.79e-137 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HNAHMFAC_00466 7.26e-308 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNAHMFAC_00467 3.54e-177 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HNAHMFAC_00468 3.07e-115 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HNAHMFAC_00469 1.87e-113 - 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
HNAHMFAC_00470 2.06e-136 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HNAHMFAC_00471 1.47e-207 yxaM - - EGP - - - Major facilitator Superfamily
HNAHMFAC_00472 3.35e-09 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HNAHMFAC_00473 3.43e-106 - - - F - - - NUDIX domain
HNAHMFAC_00474 1.65e-148 - - - F - - - Phosphorylase superfamily
HNAHMFAC_00475 1.57e-190 - - - F - - - Phosphorylase superfamily
HNAHMFAC_00476 6.17e-193 - - - F - - - Phosphorylase superfamily
HNAHMFAC_00477 8.85e-111 - - - S - - - ASCH
HNAHMFAC_00478 9.13e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNAHMFAC_00479 1.38e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HNAHMFAC_00480 2.43e-208 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HNAHMFAC_00481 5.08e-196 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HNAHMFAC_00482 1.41e-266 - - - G - - - Transmembrane secretion effector
HNAHMFAC_00483 6.32e-316 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_00484 2.24e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNAHMFAC_00485 4.33e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HNAHMFAC_00486 1.18e-223 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HNAHMFAC_00487 4.95e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
HNAHMFAC_00488 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HNAHMFAC_00489 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HNAHMFAC_00490 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HNAHMFAC_00491 4.42e-116 ypmB - - S - - - Protein conserved in bacteria
HNAHMFAC_00492 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HNAHMFAC_00493 8.07e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HNAHMFAC_00494 5.5e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNAHMFAC_00495 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HNAHMFAC_00496 5.29e-148 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNAHMFAC_00497 3.25e-136 ypsA - - S - - - Belongs to the UPF0398 family
HNAHMFAC_00498 2.77e-94 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNAHMFAC_00499 5.17e-272 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HNAHMFAC_00500 1.07e-305 cpdA - - S - - - Calcineurin-like phosphoesterase
HNAHMFAC_00501 3.83e-279 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HNAHMFAC_00502 2.67e-222 degV1 - - S - - - DegV family
HNAHMFAC_00503 7.27e-73 - - - - - - - -
HNAHMFAC_00504 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HNAHMFAC_00505 7.17e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNAHMFAC_00506 4.58e-217 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HNAHMFAC_00507 1.73e-247 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HNAHMFAC_00508 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HNAHMFAC_00509 0.0 FbpA - - K - - - Fibronectin-binding protein
HNAHMFAC_00510 2.56e-82 - - - - - - - -
HNAHMFAC_00511 3.19e-208 - - - S - - - EDD domain protein, DegV family
HNAHMFAC_00512 1.07e-193 - - - - - - - -
HNAHMFAC_00513 4.93e-211 lysR - - K - - - Transcriptional regulator
HNAHMFAC_00514 3.16e-257 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
HNAHMFAC_00515 1.55e-158 - - - S - - - Protein of unknown function (DUF1275)
HNAHMFAC_00516 7.91e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNAHMFAC_00517 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HNAHMFAC_00518 4.97e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HNAHMFAC_00519 6.88e-230 - - - K - - - Transcriptional regulator
HNAHMFAC_00521 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HNAHMFAC_00522 9.16e-138 vanZ - - V - - - VanZ like family
HNAHMFAC_00523 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNAHMFAC_00524 0.0 yclK - - T - - - Histidine kinase
HNAHMFAC_00525 1.89e-166 - - - K - - - Transcriptional regulatory protein, C terminal
HNAHMFAC_00526 7.69e-87 - - - S - - - SdpI/YhfL protein family
HNAHMFAC_00527 2.96e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HNAHMFAC_00528 3.45e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HNAHMFAC_00529 1.11e-130 - - - M - - - Protein of unknown function (DUF3737)
HNAHMFAC_00530 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
HNAHMFAC_00532 3.36e-289 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNAHMFAC_00533 1.15e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HNAHMFAC_00534 8.81e-114 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HNAHMFAC_00536 3.97e-77 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
HNAHMFAC_00537 1.86e-54 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
HNAHMFAC_00538 2.73e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HNAHMFAC_00539 5.45e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HNAHMFAC_00540 6.1e-171 yebC - - K - - - Transcriptional regulatory protein
HNAHMFAC_00541 5.31e-125 - - - S - - - VanZ like family
HNAHMFAC_00542 4.49e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNAHMFAC_00543 5.11e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HNAHMFAC_00544 5.93e-190 - - - S - - - Alpha/beta hydrolase family
HNAHMFAC_00545 7.25e-150 - - - - - - - -
HNAHMFAC_00546 1.42e-255 - - - S - - - Putative adhesin
HNAHMFAC_00547 8.65e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNAHMFAC_00548 3.02e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNAHMFAC_00549 2.8e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HNAHMFAC_00550 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNAHMFAC_00551 5.17e-223 ybbR - - S - - - YbbR-like protein
HNAHMFAC_00552 6.38e-197 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNAHMFAC_00553 9.91e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_00554 2.65e-176 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00555 2.51e-172 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_00556 1.98e-259 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HNAHMFAC_00557 2.63e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HNAHMFAC_00558 6.4e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HNAHMFAC_00559 5.02e-110 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HNAHMFAC_00560 6.09e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HNAHMFAC_00561 1.02e-172 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNAHMFAC_00562 1.29e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HNAHMFAC_00563 4.2e-122 - - - - - - - -
HNAHMFAC_00564 4.65e-112 - - - - - - - -
HNAHMFAC_00565 6.82e-139 - - - K ko:K06977 - ko00000 acetyltransferase
HNAHMFAC_00566 1.46e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HNAHMFAC_00567 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNAHMFAC_00568 7.52e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HNAHMFAC_00569 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNAHMFAC_00570 5.9e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNAHMFAC_00571 7.02e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HNAHMFAC_00572 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNAHMFAC_00573 3.72e-238 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HNAHMFAC_00575 0.0 ycaM - - E - - - amino acid
HNAHMFAC_00576 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNAHMFAC_00577 2.02e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HNAHMFAC_00578 1.54e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HNAHMFAC_00579 1.58e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HNAHMFAC_00580 2.04e-117 - - - S - - - Short repeat of unknown function (DUF308)
HNAHMFAC_00581 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HNAHMFAC_00582 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNAHMFAC_00583 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HNAHMFAC_00584 3.22e-245 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HNAHMFAC_00585 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HNAHMFAC_00586 2.52e-282 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNAHMFAC_00587 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HNAHMFAC_00588 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HNAHMFAC_00589 1.36e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HNAHMFAC_00590 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HNAHMFAC_00591 4.7e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HNAHMFAC_00592 7.28e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HNAHMFAC_00593 1.09e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNAHMFAC_00594 1.57e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HNAHMFAC_00595 5.09e-201 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNAHMFAC_00596 1.67e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNAHMFAC_00597 6.45e-41 - - - - - - - -
HNAHMFAC_00598 3.42e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNAHMFAC_00599 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNAHMFAC_00600 2.3e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNAHMFAC_00601 4.16e-159 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HNAHMFAC_00602 1.1e-279 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HNAHMFAC_00603 5.23e-152 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HNAHMFAC_00604 9.48e-262 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HNAHMFAC_00605 0.0 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HNAHMFAC_00606 1.13e-246 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNAHMFAC_00607 3.1e-125 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNAHMFAC_00608 5.66e-169 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HNAHMFAC_00609 9.25e-161 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HNAHMFAC_00610 1.66e-287 ymfH - - S - - - Peptidase M16
HNAHMFAC_00611 6.67e-281 ymfF - - S - - - Peptidase M16 inactive domain protein
HNAHMFAC_00612 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HNAHMFAC_00613 6.82e-99 - - - S - - - Protein of unknown function (DUF1149)
HNAHMFAC_00614 8e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNAHMFAC_00615 5.14e-268 XK27_05220 - - S - - - AI-2E family transporter
HNAHMFAC_00616 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HNAHMFAC_00617 1.68e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HNAHMFAC_00618 1.45e-298 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HNAHMFAC_00619 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HNAHMFAC_00620 1.54e-217 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HNAHMFAC_00621 3.58e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNAHMFAC_00622 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HNAHMFAC_00623 1.63e-139 - - - S - - - CYTH
HNAHMFAC_00624 8.57e-137 yjbH - - Q - - - Thioredoxin
HNAHMFAC_00628 4.62e-31 - - - S - - - Bacteriocin class II with double-glycine leader peptide
HNAHMFAC_00629 4.72e-134 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HNAHMFAC_00630 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HNAHMFAC_00631 6.18e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HNAHMFAC_00632 7.67e-10 - - - - - - - -
HNAHMFAC_00633 8.49e-18 - - - P ko:K10716 - ko00000,ko02000 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HNAHMFAC_00634 9.81e-261 - - - S - - - Membrane
HNAHMFAC_00635 9.79e-196 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_00636 1.21e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HNAHMFAC_00637 2.34e-97 - - - K - - - LytTr DNA-binding domain
HNAHMFAC_00638 3.27e-83 - - - S - - - Protein of unknown function (DUF3021)
HNAHMFAC_00639 9.58e-117 - - - K - - - Acetyltransferase (GNAT) domain
HNAHMFAC_00640 6.06e-227 - - - C - - - nadph quinone reductase
HNAHMFAC_00641 6.23e-102 ywnA - - K - - - Transcriptional regulator
HNAHMFAC_00642 1.17e-110 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNAHMFAC_00643 6.72e-10 - - - G - - - gluconokinase activity
HNAHMFAC_00644 1.52e-124 - - - - - - - -
HNAHMFAC_00645 1.85e-53 - - - - - - - -
HNAHMFAC_00646 3.49e-105 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HNAHMFAC_00647 4.04e-103 - - - - - - - -
HNAHMFAC_00648 6.92e-186 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HNAHMFAC_00649 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HNAHMFAC_00650 1.49e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNAHMFAC_00651 6.06e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HNAHMFAC_00652 1.37e-179 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HNAHMFAC_00653 1.73e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00654 0.0 - - - E - - - amino acid
HNAHMFAC_00655 8.98e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HNAHMFAC_00656 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNAHMFAC_00657 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNAHMFAC_00658 1.01e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNAHMFAC_00659 3.91e-268 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNAHMFAC_00660 9.05e-160 - - - S - - - (CBS) domain
HNAHMFAC_00661 1.14e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HNAHMFAC_00662 1.28e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNAHMFAC_00663 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNAHMFAC_00664 3.62e-46 yabO - - J - - - S4 domain protein
HNAHMFAC_00665 1.52e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HNAHMFAC_00666 4.65e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
HNAHMFAC_00667 1.2e-311 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNAHMFAC_00668 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNAHMFAC_00669 0.0 - - - S - - - membrane
HNAHMFAC_00670 0.0 - - - S - - - membrane
HNAHMFAC_00671 1.92e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNAHMFAC_00672 6.48e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNAHMFAC_00673 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HNAHMFAC_00675 2.5e-15 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HNAHMFAC_00677 7.76e-59 - - - V - - - Type II restriction enzyme, methylase subunits
HNAHMFAC_00678 8.8e-119 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HNAHMFAC_00679 2.24e-76 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HNAHMFAC_00680 5.89e-86 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HNAHMFAC_00684 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HNAHMFAC_00685 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAHMFAC_00686 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAHMFAC_00687 8.18e-141 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HNAHMFAC_00688 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNAHMFAC_00689 8.05e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNAHMFAC_00690 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNAHMFAC_00691 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HNAHMFAC_00692 8.75e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNAHMFAC_00693 1.57e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HNAHMFAC_00694 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNAHMFAC_00695 1.99e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNAHMFAC_00696 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNAHMFAC_00697 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNAHMFAC_00698 3.69e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNAHMFAC_00699 3e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNAHMFAC_00700 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HNAHMFAC_00701 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNAHMFAC_00702 6.02e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNAHMFAC_00703 1.18e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNAHMFAC_00704 6.1e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNAHMFAC_00705 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNAHMFAC_00706 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNAHMFAC_00707 3.04e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNAHMFAC_00708 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNAHMFAC_00709 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNAHMFAC_00710 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HNAHMFAC_00711 5.78e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HNAHMFAC_00712 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNAHMFAC_00713 4.87e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNAHMFAC_00714 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNAHMFAC_00715 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HNAHMFAC_00716 1.92e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNAHMFAC_00717 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNAHMFAC_00718 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAHMFAC_00719 3.16e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HNAHMFAC_00720 9.07e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAHMFAC_00721 2.93e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAHMFAC_00722 1.18e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAHMFAC_00723 3.17e-192 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNAHMFAC_00724 1.08e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNAHMFAC_00725 1.13e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HNAHMFAC_00727 0.0 - - - P ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
HNAHMFAC_00728 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_00729 2.67e-86 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
HNAHMFAC_00730 7.99e-194 - - - GM - - - NmrA-like family
HNAHMFAC_00731 8.56e-140 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HNAHMFAC_00732 3.17e-166 - - - G - - - Belongs to the phosphoglycerate mutase family
HNAHMFAC_00733 4.17e-67 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HNAHMFAC_00734 1.38e-197 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HNAHMFAC_00735 2.45e-53 - - - - - - - -
HNAHMFAC_00737 3.95e-159 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNAHMFAC_00738 1.15e-234 - - - S - - - AAA domain
HNAHMFAC_00739 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
HNAHMFAC_00740 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HNAHMFAC_00741 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
HNAHMFAC_00742 2.44e-166 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HNAHMFAC_00743 1.18e-146 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00745 4.37e-266 pepA - - E - - - M42 glutamyl aminopeptidase
HNAHMFAC_00746 1.57e-111 - - - - - - - -
HNAHMFAC_00747 3.59e-88 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HNAHMFAC_00748 7.28e-42 - - - - - - - -
HNAHMFAC_00749 2.77e-273 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HNAHMFAC_00750 6.1e-311 - - - E - - - amino acid
HNAHMFAC_00751 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
HNAHMFAC_00752 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HNAHMFAC_00753 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HNAHMFAC_00754 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
HNAHMFAC_00755 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HNAHMFAC_00756 0.0 - - - E - - - Phospholipase B
HNAHMFAC_00757 1.15e-143 - - - I - - - Acid phosphatase homologues
HNAHMFAC_00758 8.88e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HNAHMFAC_00759 6.02e-97 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_00760 1.47e-304 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HNAHMFAC_00761 5.2e-161 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HNAHMFAC_00762 6.44e-42 - - - S - - - PFAM Archaeal ATPase
HNAHMFAC_00763 1.05e-68 - - - S - - - PFAM Archaeal ATPase
HNAHMFAC_00764 2.12e-26 - - - S - - - PFAM Archaeal ATPase
HNAHMFAC_00765 2.91e-98 - - - K - - - acetyltransferase
HNAHMFAC_00768 1.87e-89 - - - - - - - -
HNAHMFAC_00769 0.0 qacA - - EGP - - - Major Facilitator
HNAHMFAC_00770 0.0 qacA - - EGP - - - Major Facilitator
HNAHMFAC_00771 9.83e-185 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HNAHMFAC_00772 3.62e-174 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
HNAHMFAC_00773 1.33e-204 - - - S ko:K07088 - ko00000 Membrane transport protein
HNAHMFAC_00774 5.39e-98 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HNAHMFAC_00775 2.45e-246 - - - S - - - Bacteriocin helveticin-J
HNAHMFAC_00776 6.44e-283 - - - P - - - Voltage gated chloride channel
HNAHMFAC_00777 5.09e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HNAHMFAC_00778 7.79e-112 - - - L ko:K07491 - ko00000 Transposase IS200 like
HNAHMFAC_00779 0.0 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HNAHMFAC_00780 5.37e-79 ylbE - - GM - - - NAD(P)H-binding
HNAHMFAC_00781 1.06e-52 ylbE - - GM - - - NAD(P)H-binding
HNAHMFAC_00782 1.84e-162 - - - F - - - Glutamine amidotransferase class-I
HNAHMFAC_00783 1.02e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HNAHMFAC_00785 1.05e-60 - - - - - - - -
HNAHMFAC_00786 3.79e-221 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HNAHMFAC_00787 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HNAHMFAC_00788 2.55e-216 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HNAHMFAC_00789 1.89e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNAHMFAC_00790 4.14e-176 - - - - - - - -
HNAHMFAC_00791 4.64e-277 - - - S - - - Protein of unknown function (DUF2974)
HNAHMFAC_00792 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HNAHMFAC_00793 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HNAHMFAC_00794 1.1e-146 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HNAHMFAC_00795 9.98e-261 XK27_02480 - - EGP - - - Major facilitator Superfamily
HNAHMFAC_00796 2.17e-130 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
HNAHMFAC_00797 2.46e-104 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_00798 2.55e-22 - - - HJ - - - Ribosomal protein S6 modification
HNAHMFAC_00800 5.01e-310 eriC - - P ko:K03281 - ko00000 chloride
HNAHMFAC_00801 0.0 fusA1 - - J - - - elongation factor G
HNAHMFAC_00802 1.13e-179 - - - K - - - Helix-turn-helix domain
HNAHMFAC_00803 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_00804 1.07e-23 - - - - - - - -
HNAHMFAC_00805 2.06e-196 yitS - - S - - - EDD domain protein, DegV family
HNAHMFAC_00806 2.15e-176 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HNAHMFAC_00807 5.04e-163 - - - S - - - Protein of unknown function (DUF975)
HNAHMFAC_00808 3.04e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HNAHMFAC_00809 9.98e-212 - - - I - - - Acyltransferase
HNAHMFAC_00810 1.84e-283 - - - S - - - Sterol carrier protein domain
HNAHMFAC_00812 5.27e-315 steT - - E ko:K03294 - ko00000 amino acid
HNAHMFAC_00813 2.97e-287 - - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_00814 1.45e-42 - - - - - - - -
HNAHMFAC_00815 3.16e-259 - - - EP - - - Plasmid replication protein
HNAHMFAC_00816 4.15e-120 - - - - - - - -
HNAHMFAC_00817 9.86e-110 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HNAHMFAC_00818 9.89e-24 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HNAHMFAC_00819 3.11e-71 - - - - - - - -
HNAHMFAC_00820 4.15e-232 - - - - - - - -
HNAHMFAC_00821 1.19e-77 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
HNAHMFAC_00822 8.34e-132 cadD - - P - - - Cadmium resistance transporter
HNAHMFAC_00824 0.0 - - - - - - - -
HNAHMFAC_00825 1.39e-279 - - - I - - - Protein of unknown function (DUF2974)
HNAHMFAC_00826 1.27e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HNAHMFAC_00827 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HNAHMFAC_00828 1.15e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HNAHMFAC_00829 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HNAHMFAC_00830 1.42e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HNAHMFAC_00831 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNAHMFAC_00832 2.06e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNAHMFAC_00833 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HNAHMFAC_00834 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNAHMFAC_00835 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNAHMFAC_00836 5.09e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNAHMFAC_00837 3.44e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNAHMFAC_00838 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNAHMFAC_00841 5.61e-98 - - - K - - - LytTr DNA-binding domain
HNAHMFAC_00842 1.24e-84 - - - S - - - Protein of unknown function (DUF3021)
HNAHMFAC_00843 1.42e-168 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HNAHMFAC_00844 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HNAHMFAC_00845 8.45e-106 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HNAHMFAC_00846 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HNAHMFAC_00847 2.46e-227 - - - S - - - Conserved hypothetical protein 698
HNAHMFAC_00848 1.78e-264 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HNAHMFAC_00849 4.31e-95 - - - - - - - -
HNAHMFAC_00851 5.82e-130 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HNAHMFAC_00852 3.62e-122 - - - K - - - LysR substrate binding domain
HNAHMFAC_00853 2.79e-227 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HNAHMFAC_00854 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNAHMFAC_00855 1.9e-115 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNAHMFAC_00856 2.11e-219 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
HNAHMFAC_00857 3.42e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HNAHMFAC_00858 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNAHMFAC_00859 1.19e-196 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HNAHMFAC_00860 1.27e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNAHMFAC_00861 3.46e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNAHMFAC_00862 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HNAHMFAC_00863 3.74e-48 yozE - - S - - - Belongs to the UPF0346 family
HNAHMFAC_00864 3.94e-190 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
HNAHMFAC_00865 5.61e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HNAHMFAC_00866 1.59e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNAHMFAC_00867 4.7e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNAHMFAC_00868 1.32e-76 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HNAHMFAC_00869 0.0 - - - L - - - Helicase C-terminal domain protein
HNAHMFAC_00870 3.45e-70 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HNAHMFAC_00872 3.63e-05 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HNAHMFAC_00874 3.53e-166 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HNAHMFAC_00876 0.0 - 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 EcoEI R protein C-terminal
HNAHMFAC_00878 4.18e-26 - - - H - - - RibD C-terminal domain
HNAHMFAC_00881 4.04e-06 - 3.1.3.16 - - ko:K01090 - ko00000,ko01000 -
HNAHMFAC_00883 1.76e-31 - - - - - - - -
HNAHMFAC_00884 5.56e-11 - - - - - - - -
HNAHMFAC_00887 4.32e-21 - - - - - - - -
HNAHMFAC_00888 9.78e-25 ansR - - K - - - Transcriptional regulator
HNAHMFAC_00889 5.24e-118 int3 - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_00890 4.34e-179 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HNAHMFAC_00891 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HNAHMFAC_00892 3.7e-72 yheA - - S - - - Belongs to the UPF0342 family
HNAHMFAC_00893 1.56e-276 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HNAHMFAC_00894 0.0 yhaN - - L - - - AAA domain
HNAHMFAC_00895 2.94e-235 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HNAHMFAC_00896 2.5e-202 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HNAHMFAC_00897 2.95e-48 - - - S - - - YtxH-like protein
HNAHMFAC_00898 2.56e-85 - - - - - - - -
HNAHMFAC_00899 2.38e-99 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HNAHMFAC_00900 1.38e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_00901 5.29e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HNAHMFAC_00902 9.86e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNAHMFAC_00903 3.29e-82 - - - - - - - -
HNAHMFAC_00904 1.11e-70 ytpP - - CO - - - Thioredoxin
HNAHMFAC_00905 8.43e-155 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNAHMFAC_00906 3.96e-111 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HNAHMFAC_00907 5.18e-222 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HNAHMFAC_00908 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNAHMFAC_00909 3.57e-151 - - - S - - - repeat protein
HNAHMFAC_00910 5.5e-162 pgm - - G - - - Phosphoglycerate mutase family
HNAHMFAC_00911 9.01e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNAHMFAC_00912 1.27e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HNAHMFAC_00913 2.13e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HNAHMFAC_00914 1.02e-164 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNAHMFAC_00915 2.89e-48 - - - - - - - -
HNAHMFAC_00916 1.81e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HNAHMFAC_00917 1.37e-45 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HNAHMFAC_00918 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNAHMFAC_00919 5.54e-156 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HNAHMFAC_00920 1.39e-187 ylmH - - S - - - S4 domain protein
HNAHMFAC_00921 1.36e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HNAHMFAC_00922 1.17e-90 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HNAHMFAC_00923 7.41e-310 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNAHMFAC_00924 5.2e-309 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNAHMFAC_00925 4.13e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNAHMFAC_00926 2.74e-265 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNAHMFAC_00927 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNAHMFAC_00928 1.05e-225 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNAHMFAC_00929 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HNAHMFAC_00930 3.95e-73 ftsL - - D - - - Cell division protein FtsL
HNAHMFAC_00931 1.02e-229 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNAHMFAC_00932 1.89e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HNAHMFAC_00933 2.2e-68 - - - S - - - Protein of unknown function (DUF3397)
HNAHMFAC_00934 2.36e-19 - - - S - - - Protein of unknown function (DUF4044)
HNAHMFAC_00935 3.99e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
HNAHMFAC_00936 1.37e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HNAHMFAC_00937 3.11e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HNAHMFAC_00938 1.85e-143 radC - - L ko:K03630 - ko00000 DNA repair protein
HNAHMFAC_00939 1.1e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
HNAHMFAC_00940 2.33e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HNAHMFAC_00941 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNAHMFAC_00942 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HNAHMFAC_00943 2.23e-229 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
HNAHMFAC_00944 3.13e-159 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HNAHMFAC_00945 4.43e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNAHMFAC_00946 6.1e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HNAHMFAC_00947 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNAHMFAC_00949 7.54e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNAHMFAC_00950 7.2e-108 - - - S - - - Protein of unknown function (DUF1694)
HNAHMFAC_00951 3.75e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HNAHMFAC_00952 9.34e-08 - - - - - - - -
HNAHMFAC_00953 3.52e-106 uspA - - T - - - universal stress protein
HNAHMFAC_00954 1.85e-284 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HNAHMFAC_00955 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
HNAHMFAC_00956 5.54e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HNAHMFAC_00957 3.34e-18 - - - S - - - DNA-directed RNA polymerase subunit beta
HNAHMFAC_00958 2.04e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HNAHMFAC_00959 3.07e-42 - - - S - - - Protein of unknown function (DUF1146)
HNAHMFAC_00960 2.1e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HNAHMFAC_00961 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNAHMFAC_00962 1.21e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNAHMFAC_00963 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNAHMFAC_00964 1.13e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNAHMFAC_00965 5.6e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNAHMFAC_00966 1.75e-35 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNAHMFAC_00967 7.4e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HNAHMFAC_00968 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNAHMFAC_00969 8.5e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNAHMFAC_00970 5.31e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNAHMFAC_00971 4.43e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNAHMFAC_00972 8.2e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HNAHMFAC_00973 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HNAHMFAC_00974 7.92e-247 ampC - - V - - - Beta-lactamase
HNAHMFAC_00977 3.21e-89 - - - - - - - -
HNAHMFAC_00978 1.96e-153 - - - EGP - - - Major Facilitator
HNAHMFAC_00979 4.78e-198 - - - M - - - ErfK YbiS YcfS YnhG
HNAHMFAC_00980 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HNAHMFAC_00981 2.22e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HNAHMFAC_00982 2.01e-179 - - - K - - - Helix-turn-helix domain, rpiR family
HNAHMFAC_00983 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
HNAHMFAC_00985 2.41e-149 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HNAHMFAC_00986 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HNAHMFAC_00987 1.69e-157 - - - S - - - Peptidase_C39 like family
HNAHMFAC_00988 1.13e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
HNAHMFAC_00989 7.58e-210 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HNAHMFAC_00990 1.32e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNAHMFAC_00992 2.49e-166 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HNAHMFAC_00993 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNAHMFAC_00994 1.88e-316 yycH - - S - - - YycH protein
HNAHMFAC_00995 1.62e-190 yycI - - S - - - YycH protein
HNAHMFAC_00996 2.14e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HNAHMFAC_00997 1.94e-235 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HNAHMFAC_00998 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNAHMFAC_00999 6.57e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HNAHMFAC_01000 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01001 5.59e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HNAHMFAC_01002 5.14e-216 - - - K - - - helix_turn_helix, arabinose operon control protein
HNAHMFAC_01003 2.96e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HNAHMFAC_01004 2.67e-125 lemA - - S ko:K03744 - ko00000 LemA family
HNAHMFAC_01005 3.5e-235 ysdE - - P - - - Citrate transporter
HNAHMFAC_01006 4.71e-84 - - - S - - - Iron-sulphur cluster biosynthesis
HNAHMFAC_01007 1.14e-23 - - - - - - - -
HNAHMFAC_01008 1.53e-151 - - - - - - - -
HNAHMFAC_01010 1.08e-304 - - - M - - - Glycosyl transferase
HNAHMFAC_01011 4.11e-253 - - - G - - - Glycosyl hydrolases family 8
HNAHMFAC_01012 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HNAHMFAC_01013 7.83e-208 - - - L - - - HNH nucleases
HNAHMFAC_01014 5.01e-61 - - - - - - - -
HNAHMFAC_01015 1.19e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01016 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_01017 3.58e-148 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HNAHMFAC_01018 4.1e-84 yeaO - - S - - - Protein of unknown function, DUF488
HNAHMFAC_01019 2.07e-166 terC - - P - - - Integral membrane protein TerC family
HNAHMFAC_01020 6.09e-113 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
HNAHMFAC_01021 5.68e-173 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HNAHMFAC_01022 1.28e-103 - - - - - - - -
HNAHMFAC_01023 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNAHMFAC_01024 5.18e-159 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HNAHMFAC_01025 5.21e-225 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HNAHMFAC_01026 5.53e-180 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNAHMFAC_01028 2.02e-220 - - - S - - - Protein of unknown function (DUF1002)
HNAHMFAC_01029 5.52e-204 epsV - - S - - - glycosyl transferase family 2
HNAHMFAC_01030 3.44e-161 - - - S - - - Alpha/beta hydrolase family
HNAHMFAC_01031 1.13e-81 - - - - - - - -
HNAHMFAC_01032 6.1e-230 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNAHMFAC_01033 1.37e-306 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HNAHMFAC_01034 9.32e-145 - - - K - - - Bacterial regulatory proteins, tetR family
HNAHMFAC_01035 3.43e-163 - - - - - - - -
HNAHMFAC_01036 0.0 - - - S - - - Cysteine-rich secretory protein family
HNAHMFAC_01037 6.44e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HNAHMFAC_01038 9.56e-127 - - - - - - - -
HNAHMFAC_01039 1.7e-309 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HNAHMFAC_01040 1.65e-215 yibE - - S - - - overlaps another CDS with the same product name
HNAHMFAC_01041 9.33e-155 yibF - - S - - - overlaps another CDS with the same product name
HNAHMFAC_01042 8.43e-197 - - - I - - - alpha/beta hydrolase fold
HNAHMFAC_01043 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HNAHMFAC_01044 4.99e-163 - - - K ko:K03710 - ko00000,ko03000 UTRA
HNAHMFAC_01045 1.61e-273 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
HNAHMFAC_01046 4.21e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNAHMFAC_01047 2.28e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HNAHMFAC_01048 1.63e-190 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HNAHMFAC_01049 1.02e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HNAHMFAC_01050 6.28e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HNAHMFAC_01051 1.88e-233 - - - S - - - zinc-ribbon domain
HNAHMFAC_01052 1.56e-113 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HNAHMFAC_01053 7.17e-128 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HNAHMFAC_01054 3.53e-169 - - - K - - - UTRA domain
HNAHMFAC_01055 5.05e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HNAHMFAC_01056 6.03e-114 usp5 - - T - - - universal stress protein
HNAHMFAC_01058 1.16e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HNAHMFAC_01059 1.28e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HNAHMFAC_01060 1.11e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNAHMFAC_01061 4.13e-187 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNAHMFAC_01062 3.38e-109 - - - - - - - -
HNAHMFAC_01063 0.0 - - - S - - - Calcineurin-like phosphoesterase
HNAHMFAC_01064 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HNAHMFAC_01065 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HNAHMFAC_01066 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HNAHMFAC_01067 3.57e-176 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNAHMFAC_01068 8.83e-134 yitW - - S - - - Iron-sulfur cluster assembly protein
HNAHMFAC_01069 5.16e-291 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HNAHMFAC_01070 1.37e-288 yqjV - - EGP - - - Major Facilitator Superfamily
HNAHMFAC_01071 9.45e-235 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
HNAHMFAC_01072 0.0 - - - D - - - transport
HNAHMFAC_01073 1.33e-174 rpl - - K - - - Helix-turn-helix domain, rpiR family
HNAHMFAC_01074 1.3e-209 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HNAHMFAC_01076 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HNAHMFAC_01077 0.0 - - - S - - - Bacterial membrane protein, YfhO
HNAHMFAC_01078 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HNAHMFAC_01079 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HNAHMFAC_01080 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HNAHMFAC_01081 8.74e-95 - - - - - - - -
HNAHMFAC_01082 1.17e-175 - - - - - - - -
HNAHMFAC_01083 3.41e-37 - - - - - - - -
HNAHMFAC_01084 3.38e-46 - - - S - - - Protein of unknown function (DUF2922)
HNAHMFAC_01085 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNAHMFAC_01086 1.22e-303 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HNAHMFAC_01087 2.19e-182 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HNAHMFAC_01088 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HNAHMFAC_01089 8.33e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HNAHMFAC_01090 9.73e-181 - - - - - - - -
HNAHMFAC_01091 3.27e-191 - - - - - - - -
HNAHMFAC_01092 1.69e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HNAHMFAC_01093 2.23e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNAHMFAC_01094 1.15e-63 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
HNAHMFAC_01095 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNAHMFAC_01096 9.65e-95 - - - S - - - GtrA-like protein
HNAHMFAC_01097 1.56e-227 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HNAHMFAC_01098 1.2e-149 - - - - - - - -
HNAHMFAC_01099 2.21e-195 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HNAHMFAC_01100 5.58e-217 yqhA - - G - - - Aldose 1-epimerase
HNAHMFAC_01101 8.33e-255 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HNAHMFAC_01102 3.45e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNAHMFAC_01103 0.0 XK27_08315 - - M - - - Sulfatase
HNAHMFAC_01104 2.08e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNAHMFAC_01106 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HNAHMFAC_01107 1.29e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HNAHMFAC_01108 1.52e-39 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
HNAHMFAC_01109 5.22e-54 - - - K - - - sequence-specific DNA binding
HNAHMFAC_01110 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HNAHMFAC_01111 4.43e-65 - - - - - - - -
HNAHMFAC_01112 1.83e-96 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNAHMFAC_01113 3.6e-101 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HNAHMFAC_01114 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_01115 8.81e-103 - - - - - - - -
HNAHMFAC_01116 2.77e-316 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAHMFAC_01117 3.42e-167 - - - K ko:K03489 - ko00000,ko03000 UTRA
HNAHMFAC_01118 1.86e-94 - - - S - - - Domain of unknown function (DUF3284)
HNAHMFAC_01119 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_01120 1.63e-174 - - - K ko:K03492 - ko00000,ko03000 UTRA
HNAHMFAC_01121 1.02e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HNAHMFAC_01122 3.28e-52 - - - - - - - -
HNAHMFAC_01123 2.32e-28 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HNAHMFAC_01124 7.05e-28 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HNAHMFAC_01125 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAHMFAC_01126 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_01127 1.18e-194 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HNAHMFAC_01128 3.27e-150 - - - - - - - -
HNAHMFAC_01130 1.03e-149 - - - E - - - Belongs to the SOS response-associated peptidase family
HNAHMFAC_01131 2.46e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HNAHMFAC_01132 9.68e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
HNAHMFAC_01133 2.07e-127 - - - S ko:K06872 - ko00000 TPM domain
HNAHMFAC_01134 5.01e-233 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HNAHMFAC_01135 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNAHMFAC_01136 1.84e-188 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HNAHMFAC_01137 6.53e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNAHMFAC_01138 1.15e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNAHMFAC_01139 1.22e-48 veg - - S - - - Biofilm formation stimulator VEG
HNAHMFAC_01140 6.33e-310 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HNAHMFAC_01141 3.13e-90 - - - S - - - Iron-sulphur cluster biosynthesis
HNAHMFAC_01142 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNAHMFAC_01143 0.0 eriC - - P ko:K03281 - ko00000 chloride
HNAHMFAC_01144 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNAHMFAC_01145 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HNAHMFAC_01146 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNAHMFAC_01147 9.02e-317 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNAHMFAC_01148 3.99e-200 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNAHMFAC_01149 3.49e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNAHMFAC_01150 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HNAHMFAC_01151 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HNAHMFAC_01152 2.89e-227 - - - - - - - -
HNAHMFAC_01153 1.29e-164 - - - S - - - SNARE associated Golgi protein
HNAHMFAC_01154 7.39e-184 - - - S - - - haloacid dehalogenase-like hydrolase
HNAHMFAC_01155 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HNAHMFAC_01156 3.1e-125 yobS - - K - - - Bacterial regulatory proteins, tetR family
HNAHMFAC_01157 4.44e-204 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HNAHMFAC_01158 1.86e-213 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HNAHMFAC_01159 8.58e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
HNAHMFAC_01160 3.03e-112 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HNAHMFAC_01161 5.28e-100 yybA - - K - - - Transcriptional regulator
HNAHMFAC_01162 1.37e-74 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HNAHMFAC_01163 1.48e-306 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HNAHMFAC_01164 4.66e-314 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
HNAHMFAC_01165 1.96e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HNAHMFAC_01166 3.57e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
HNAHMFAC_01167 8.41e-260 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HNAHMFAC_01168 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HNAHMFAC_01169 4.84e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HNAHMFAC_01170 4.36e-200 dkgB - - S - - - reductase
HNAHMFAC_01171 1.67e-252 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HNAHMFAC_01172 4.31e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
HNAHMFAC_01173 7.15e-191 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HNAHMFAC_01174 4.85e-143 yviA - - S - - - Protein of unknown function (DUF421)
HNAHMFAC_01175 1.3e-94 - - - S - - - Protein of unknown function (DUF3290)
HNAHMFAC_01176 2.02e-308 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HNAHMFAC_01177 1.19e-120 - - - S - - - PAS domain
HNAHMFAC_01178 4.68e-186 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HNAHMFAC_01179 0.0 - - - GM ko:K13732 ko05100,map05100 ko00000,ko00001 domain, Protein
HNAHMFAC_01180 2.42e-69 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HNAHMFAC_01181 2.19e-111 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HNAHMFAC_01182 9.55e-118 - - - - - - - -
HNAHMFAC_01183 1.75e-187 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HNAHMFAC_01184 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HNAHMFAC_01185 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HNAHMFAC_01186 1.63e-180 - - - S - - - PAS domain
HNAHMFAC_01187 9.86e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNAHMFAC_01188 6.12e-257 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HNAHMFAC_01189 3.15e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNAHMFAC_01190 4.61e-84 - - - - - - - -
HNAHMFAC_01191 9.38e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HNAHMFAC_01192 5.58e-180 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HNAHMFAC_01193 5.13e-215 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HNAHMFAC_01194 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HNAHMFAC_01195 1.12e-194 - - - EG - - - EamA-like transporter family
HNAHMFAC_01196 7.81e-135 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_01197 3.62e-93 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HNAHMFAC_01198 4.55e-99 - - - M - - - Rib/alpha-like repeat
HNAHMFAC_01200 2.51e-49 - - - S - - - Bacterial protein of unknown function (DUF898)
HNAHMFAC_01201 1.21e-45 - - - K - - - SIS domain
HNAHMFAC_01202 5.98e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
HNAHMFAC_01205 4.86e-69 XK27_05625 - - P - - - Rhodanese Homology Domain
HNAHMFAC_01206 2.62e-244 - - - - - - - -
HNAHMFAC_01207 2.57e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
HNAHMFAC_01208 1.44e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HNAHMFAC_01209 6.86e-174 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HNAHMFAC_01210 2.84e-263 - - - M - - - Glycosyl transferases group 1
HNAHMFAC_01211 0.0 - - - S - - - Glycosyltransferase like family 2
HNAHMFAC_01212 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNAHMFAC_01213 9.12e-199 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNAHMFAC_01214 0.0 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
HNAHMFAC_01215 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HNAHMFAC_01216 0.0 - - - V - - - ABC transporter transmembrane region
HNAHMFAC_01217 6.56e-183 - - - - - - - -
HNAHMFAC_01218 3.19e-286 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HNAHMFAC_01219 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HNAHMFAC_01220 9.44e-170 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HNAHMFAC_01221 1.07e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HNAHMFAC_01223 7.99e-130 - - - S - - - ECF transporter, substrate-specific component
HNAHMFAC_01224 2.32e-144 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HNAHMFAC_01225 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HNAHMFAC_01226 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNAHMFAC_01227 6.45e-264 camS - - S - - - sex pheromone
HNAHMFAC_01228 2.23e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNAHMFAC_01229 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNAHMFAC_01230 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNAHMFAC_01231 1.47e-212 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HNAHMFAC_01233 2.3e-189 - - - S - - - hydrolase
HNAHMFAC_01234 3.2e-09 - - - UW - - - Tetratricopeptide repeat
HNAHMFAC_01236 2.23e-108 - - - - - - - -
HNAHMFAC_01237 1.62e-115 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNAHMFAC_01238 5.34e-134 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HNAHMFAC_01239 4.32e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNAHMFAC_01240 2.09e-277 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNAHMFAC_01241 2.45e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNAHMFAC_01242 9.52e-205 - - - - - - - -
HNAHMFAC_01243 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNAHMFAC_01244 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNAHMFAC_01245 1.27e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HNAHMFAC_01246 8.31e-228 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HNAHMFAC_01247 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HNAHMFAC_01248 3.18e-140 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HNAHMFAC_01249 1.39e-234 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HNAHMFAC_01250 3.34e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNAHMFAC_01251 8.64e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HNAHMFAC_01252 4e-66 ylbG - - S - - - UPF0298 protein
HNAHMFAC_01253 1.36e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HNAHMFAC_01254 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HNAHMFAC_01255 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNAHMFAC_01256 3.08e-47 ykzG - - S - - - Belongs to the UPF0356 family
HNAHMFAC_01257 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNAHMFAC_01258 9.48e-156 - - - S - - - Rib/alpha-like repeat
HNAHMFAC_01259 1.15e-86 - - - S - - - Domain of unknown function DUF1828
HNAHMFAC_01260 1.48e-90 - - - - - - - -
HNAHMFAC_01261 1.41e-65 - - - - - - - -
HNAHMFAC_01262 3.63e-104 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HNAHMFAC_01263 6.6e-162 - - - - - - - -
HNAHMFAC_01265 1.9e-205 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
HNAHMFAC_01266 2.18e-109 - - - K - - - IrrE N-terminal-like domain
HNAHMFAC_01268 1.47e-241 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNAHMFAC_01269 1.21e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HNAHMFAC_01270 1.2e-207 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNAHMFAC_01271 7.8e-266 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HNAHMFAC_01272 4.7e-283 - - - KQ - - - helix_turn_helix, mercury resistance
HNAHMFAC_01273 1.81e-42 - - - D - - - nuclear chromosome segregation
HNAHMFAC_01274 4.01e-63 - 3.1.3.97 - D ko:K07053,ko:K18491 ko04550,map04550 ko00000,ko00001,ko01000,ko03000 nuclear chromosome segregation
HNAHMFAC_01275 5.55e-29 - - - S - - - DNA/RNA non-specific endonuclease
HNAHMFAC_01277 3.25e-39 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNAHMFAC_01278 2.58e-181 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HNAHMFAC_01279 1.07e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HNAHMFAC_01280 2.74e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HNAHMFAC_01281 1.56e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HNAHMFAC_01282 1.03e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HNAHMFAC_01283 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HNAHMFAC_01284 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HNAHMFAC_01285 1.94e-267 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HNAHMFAC_01286 2.66e-45 - - - - - - - -
HNAHMFAC_01287 5.25e-79 - - - - - - - -
HNAHMFAC_01288 0.0 - - - S - - - ABC transporter
HNAHMFAC_01289 5.17e-176 - - - S - - - Putative threonine/serine exporter
HNAHMFAC_01290 6.36e-103 - - - S - - - Threonine/Serine exporter, ThrE
HNAHMFAC_01291 2.48e-52 - - - - - - - -
HNAHMFAC_01292 2.54e-77 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HNAHMFAC_01293 2.66e-102 - - - - - - - -
HNAHMFAC_01294 1.55e-224 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNAHMFAC_01295 6.17e-104 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HNAHMFAC_01296 2.23e-142 - - - - - - - -
HNAHMFAC_01297 0.0 - - - S - - - O-antigen ligase like membrane protein
HNAHMFAC_01298 1.87e-58 - - - - - - - -
HNAHMFAC_01299 1.18e-128 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HNAHMFAC_01300 2.06e-178 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HNAHMFAC_01301 1.22e-291 - - - S - - - Putative peptidoglycan binding domain
HNAHMFAC_01302 3.69e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNAHMFAC_01303 0.0 - - - E - - - Amino Acid
HNAHMFAC_01304 2.68e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01305 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HNAHMFAC_01306 4.19e-160 gpm2 - - G - - - Phosphoglycerate mutase family
HNAHMFAC_01307 1.08e-34 - - - - - - - -
HNAHMFAC_01308 1.65e-69 - - - - - - - -
HNAHMFAC_01309 2.39e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HNAHMFAC_01311 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HNAHMFAC_01312 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HNAHMFAC_01313 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNAHMFAC_01314 4.37e-206 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
HNAHMFAC_01315 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
HNAHMFAC_01316 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
HNAHMFAC_01317 1.12e-268 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
HNAHMFAC_01318 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
HNAHMFAC_01323 8.29e-09 - - - - - - - -
HNAHMFAC_01324 1.51e-314 yagE - - E - - - amino acid
HNAHMFAC_01325 2.23e-149 - - - GM - - - NmrA-like family
HNAHMFAC_01326 7.18e-190 - - - L - - - Phage integrase, N-terminal SAM-like domain
HNAHMFAC_01327 8.36e-131 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HNAHMFAC_01328 5.83e-222 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
HNAHMFAC_01329 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNAHMFAC_01330 5.13e-304 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNAHMFAC_01331 0.0 oatA - - I - - - Acyltransferase
HNAHMFAC_01332 6.85e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNAHMFAC_01333 7.14e-185 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAHMFAC_01334 8.03e-63 - - - S - - - Lipopolysaccharide assembly protein A domain
HNAHMFAC_01335 3.88e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HNAHMFAC_01336 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HNAHMFAC_01337 7.45e-36 - - - S - - - Protein of unknown function (DUF2929)
HNAHMFAC_01338 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HNAHMFAC_01339 1.69e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNAHMFAC_01340 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HNAHMFAC_01341 9.56e-211 yitL - - S ko:K00243 - ko00000 S1 domain
HNAHMFAC_01342 7.9e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HNAHMFAC_01343 1.95e-82 ribT - - K ko:K02859 - ko00000 acetyltransferase
HNAHMFAC_01344 2.78e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNAHMFAC_01345 1.59e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNAHMFAC_01346 4.82e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HNAHMFAC_01347 1.18e-107 - - - M - - - Lysin motif
HNAHMFAC_01348 7.74e-124 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNAHMFAC_01349 8.44e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HNAHMFAC_01350 6.93e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HNAHMFAC_01351 1.28e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HNAHMFAC_01352 1.37e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNAHMFAC_01353 1.71e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HNAHMFAC_01354 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HNAHMFAC_01355 1.5e-20 - - - S - - - CsbD-like
HNAHMFAC_01356 1.83e-54 - - - S - - - Transglycosylase associated protein
HNAHMFAC_01357 5.32e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HNAHMFAC_01358 0.0 - - - L - - - Helicase C-terminal domain protein
HNAHMFAC_01359 4.56e-176 - - - S - - - Alpha beta hydrolase
HNAHMFAC_01360 1.02e-35 - - - - - - - -
HNAHMFAC_01361 1.59e-226 ydbI - - K - - - AI-2E family transporter
HNAHMFAC_01362 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HNAHMFAC_01363 2.28e-271 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNAHMFAC_01364 8.92e-136 - - - E - - - GDSL-like Lipase/Acylhydrolase
HNAHMFAC_01365 1.59e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNAHMFAC_01366 0.0 - - - S - - - domain, Protein
HNAHMFAC_01367 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HNAHMFAC_01368 3.19e-212 - - - K - - - LysR substrate binding domain
HNAHMFAC_01369 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HNAHMFAC_01370 4.71e-288 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HNAHMFAC_01371 1.55e-171 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HNAHMFAC_01372 8.35e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HNAHMFAC_01373 5.19e-111 - - - S - - - Peptidase propeptide and YPEB domain
HNAHMFAC_01374 8.77e-237 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HNAHMFAC_01375 4.06e-315 - - - P - - - Major Facilitator Superfamily
HNAHMFAC_01376 7.19e-314 - - - P - - - Major Facilitator Superfamily
HNAHMFAC_01377 3.48e-212 arbZ - - I - - - Phosphate acyltransferases
HNAHMFAC_01378 2.24e-239 - - - M - - - Glycosyl transferase family 8
HNAHMFAC_01379 6.91e-234 - - - M - - - Glycosyl transferase family 8
HNAHMFAC_01380 5.7e-196 arbx - - M - - - Glycosyl transferase family 8
HNAHMFAC_01381 3.29e-187 - - - I - - - Acyl-transferase
HNAHMFAC_01383 0.0 mdr - - EGP - - - Major Facilitator
HNAHMFAC_01384 5.01e-275 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNAHMFAC_01391 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HNAHMFAC_01392 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HNAHMFAC_01393 0.0 - - - E - - - Peptidase family C69
HNAHMFAC_01394 5.65e-277 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
HNAHMFAC_01395 2.39e-193 - - - S - - - Alpha beta hydrolase
HNAHMFAC_01396 2e-85 - - - K - - - Transcriptional regulator, MarR family
HNAHMFAC_01397 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01398 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
HNAHMFAC_01399 5.43e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_01400 3.67e-175 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01401 2.91e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HNAHMFAC_01402 1.75e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_01403 3.24e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HNAHMFAC_01404 1.14e-83 - - - - - - - -
HNAHMFAC_01405 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HNAHMFAC_01406 1.74e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HNAHMFAC_01407 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNAHMFAC_01408 2.39e-109 - - - S - - - Putative adhesin
HNAHMFAC_01410 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HNAHMFAC_01412 2.32e-260 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HNAHMFAC_01413 1.65e-252 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HNAHMFAC_01414 1.91e-99 coiA - - S ko:K06198 - ko00000 Competence protein
HNAHMFAC_01415 1.15e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HNAHMFAC_01416 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNAHMFAC_01417 1.39e-84 - - - K - - - Acetyltransferase (GNAT) domain
HNAHMFAC_01418 1.61e-313 ynbB - - P - - - aluminum resistance
HNAHMFAC_01419 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HNAHMFAC_01420 0.0 - - - E - - - Amino acid permease
HNAHMFAC_01421 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HNAHMFAC_01422 7.67e-66 - - - S - - - Cupredoxin-like domain
HNAHMFAC_01423 1.25e-85 - - - S - - - Cupredoxin-like domain
HNAHMFAC_01424 3.79e-96 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
HNAHMFAC_01425 3.21e-117 - - - - - - - -
HNAHMFAC_01426 2.73e-107 - - - - - - - -
HNAHMFAC_01427 2.07e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HNAHMFAC_01428 1.21e-98 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HNAHMFAC_01429 1.38e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HNAHMFAC_01430 3.28e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HNAHMFAC_01431 8.01e-143 - - - K - - - helix_turn_helix, mercury resistance
HNAHMFAC_01432 6.61e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HNAHMFAC_01433 6.39e-299 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HNAHMFAC_01434 1.9e-160 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HNAHMFAC_01435 8.43e-155 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HNAHMFAC_01436 9.42e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNAHMFAC_01437 2.73e-201 - - - S - - - Aldo/keto reductase family
HNAHMFAC_01438 1.41e-164 - - - S ko:K07090 - ko00000 membrane transporter protein
HNAHMFAC_01439 2.06e-237 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
HNAHMFAC_01440 2.01e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
HNAHMFAC_01441 3.34e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HNAHMFAC_01442 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HNAHMFAC_01443 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HNAHMFAC_01444 1.56e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HNAHMFAC_01445 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HNAHMFAC_01446 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01447 2.79e-255 - - - S - - - DUF218 domain
HNAHMFAC_01448 2.57e-140 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HNAHMFAC_01449 9.16e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HNAHMFAC_01450 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HNAHMFAC_01453 3.74e-98 yhaH - - S - - - Protein of unknown function (DUF805)
HNAHMFAC_01454 5.8e-146 - - - S - - - Protein of unknown function (DUF969)
HNAHMFAC_01455 1.37e-199 - - - S - - - Protein of unknown function (DUF979)
HNAHMFAC_01456 6.93e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HNAHMFAC_01457 6.69e-47 - - - - - - - -
HNAHMFAC_01458 1.1e-195 mutR - - K - - - Helix-turn-helix XRE-family like proteins
HNAHMFAC_01459 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HNAHMFAC_01460 2.16e-133 - - - S - - - Putative adhesin
HNAHMFAC_01461 6.87e-258 napA - - P - - - Sodium/hydrogen exchanger family
HNAHMFAC_01462 0.0 cadA - - P - - - P-type ATPase
HNAHMFAC_01463 4.76e-111 ykuL - - S - - - (CBS) domain
HNAHMFAC_01464 5.45e-61 - - - - - - - -
HNAHMFAC_01465 1.88e-66 - - - - - - - -
HNAHMFAC_01466 1.18e-78 - - - - - - - -
HNAHMFAC_01468 4.96e-270 - - - S - - - Membrane
HNAHMFAC_01469 6.13e-52 - - - - - - - -
HNAHMFAC_01470 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HNAHMFAC_01471 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNAHMFAC_01472 4.7e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HNAHMFAC_01473 5.16e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNAHMFAC_01474 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNAHMFAC_01475 9.78e-187 pbpX2 - - V - - - Beta-lactamase
HNAHMFAC_01476 3.97e-275 - - - E - - - Major Facilitator Superfamily
HNAHMFAC_01477 8.59e-53 - - - - - - - -
HNAHMFAC_01478 1.23e-312 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAHMFAC_01479 1.13e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HNAHMFAC_01480 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
HNAHMFAC_01481 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HNAHMFAC_01482 2.46e-12 - - - - - - - -
HNAHMFAC_01484 0.000473 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HNAHMFAC_01488 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNAHMFAC_01489 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNAHMFAC_01490 4.65e-149 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNAHMFAC_01491 7.56e-148 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HNAHMFAC_01492 1.47e-211 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HNAHMFAC_01493 9.32e-143 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HNAHMFAC_01494 1.52e-43 - - - - - - - -
HNAHMFAC_01495 1.13e-219 - - - S ko:K07045 - ko00000 Amidohydrolase
HNAHMFAC_01496 3.58e-300 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HNAHMFAC_01497 2.35e-187 - - - C - - - Aldo keto reductase
HNAHMFAC_01498 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HNAHMFAC_01499 1.54e-91 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HNAHMFAC_01500 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HNAHMFAC_01501 7.37e-100 - - - S - - - Cupin domain
HNAHMFAC_01502 1.22e-113 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNAHMFAC_01503 1.08e-12 - - - S - - - Antibiotic biosynthesis monooxygenase
HNAHMFAC_01505 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HNAHMFAC_01506 2.24e-176 - - - S - - - PFAM Archaeal ATPase
HNAHMFAC_01507 6.18e-30 - - - S - - - PFAM Archaeal ATPase
HNAHMFAC_01508 4.53e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HNAHMFAC_01509 0.000103 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HNAHMFAC_01510 6.38e-179 - - - H - - - Nodulation protein S (NodS)
HNAHMFAC_01511 1.24e-194 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HNAHMFAC_01512 1.87e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNAHMFAC_01513 3.68e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HNAHMFAC_01514 6.86e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HNAHMFAC_01515 4.11e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNAHMFAC_01516 1.5e-243 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNAHMFAC_01517 7.24e-109 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNAHMFAC_01518 1.75e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNAHMFAC_01519 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HNAHMFAC_01520 3.69e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HNAHMFAC_01521 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
HNAHMFAC_01522 6.64e-140 ybbB - - S - - - Protein of unknown function (DUF1211)
HNAHMFAC_01524 2.26e-142 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HNAHMFAC_01525 3.45e-150 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HNAHMFAC_01526 5.88e-163 - - - T - - - Transcriptional regulatory protein, C terminal
HNAHMFAC_01527 7.17e-313 - - - T - - - GHKL domain
HNAHMFAC_01528 9.51e-118 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HNAHMFAC_01529 1.81e-14 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HNAHMFAC_01530 6.27e-77 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HNAHMFAC_01531 3.88e-133 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HNAHMFAC_01532 6.62e-315 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HNAHMFAC_01533 9.94e-76 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HNAHMFAC_01534 3.81e-131 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HNAHMFAC_01535 1.23e-37 - - - L ko:K07483 - ko00000 transposase activity
HNAHMFAC_01536 7.38e-23 - - - UW - - - Tetratricopeptide repeat
HNAHMFAC_01537 3.22e-251 - - - M - - - family 8
HNAHMFAC_01538 0.0 - - - M - - - family 8
HNAHMFAC_01539 0.0 - - - M - - - family 8
HNAHMFAC_01540 1.09e-151 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HNAHMFAC_01541 1.8e-184 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HNAHMFAC_01542 1.08e-57 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01543 4.99e-308 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HNAHMFAC_01544 2.31e-166 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01545 7.4e-155 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HNAHMFAC_01546 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNAHMFAC_01547 1.38e-61 - - - K - - - TRANSCRIPTIONal
HNAHMFAC_01548 5.77e-15 cinI - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HNAHMFAC_01549 1.36e-45 cinI - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HNAHMFAC_01550 1.89e-123 - - - - - - - -
HNAHMFAC_01551 9.31e-184 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HNAHMFAC_01552 3.19e-241 flp - - V - - - Beta-lactamase
HNAHMFAC_01553 1.23e-179 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
HNAHMFAC_01554 1.36e-99 - - - L - - - NUDIX domain
HNAHMFAC_01555 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HNAHMFAC_01556 2.59e-231 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNAHMFAC_01557 2.9e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HNAHMFAC_01558 2.71e-281 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
HNAHMFAC_01565 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNAHMFAC_01566 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNAHMFAC_01567 2.75e-143 - - - - - - - -
HNAHMFAC_01568 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
HNAHMFAC_01569 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNAHMFAC_01570 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNAHMFAC_01571 3.1e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNAHMFAC_01572 5.68e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNAHMFAC_01573 2.39e-75 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HNAHMFAC_01574 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNAHMFAC_01575 6.98e-265 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAHMFAC_01576 1.24e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HNAHMFAC_01577 1.61e-294 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNAHMFAC_01578 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNAHMFAC_01579 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
HNAHMFAC_01580 2.9e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNAHMFAC_01581 2.02e-63 yrzB - - S - - - Belongs to the UPF0473 family
HNAHMFAC_01582 5.63e-120 cvpA - - S - - - Colicin V production protein
HNAHMFAC_01583 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNAHMFAC_01584 8.93e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HNAHMFAC_01585 3.65e-90 yslB - - S - - - Protein of unknown function (DUF2507)
HNAHMFAC_01586 3.54e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HNAHMFAC_01587 1.47e-151 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNAHMFAC_01588 1.55e-273 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNAHMFAC_01589 4.09e-169 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HNAHMFAC_01590 2.92e-37 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNAHMFAC_01591 1.09e-63 - - - - - - - -
HNAHMFAC_01592 2.01e-266 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HNAHMFAC_01593 1.38e-227 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HNAHMFAC_01594 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
HNAHMFAC_01595 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HNAHMFAC_01596 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HNAHMFAC_01597 1.39e-74 - - - - - - - -
HNAHMFAC_01598 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HNAHMFAC_01599 1.97e-124 yutD - - S - - - Protein of unknown function (DUF1027)
HNAHMFAC_01600 5.46e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNAHMFAC_01601 1.58e-133 - - - S - - - Protein of unknown function (DUF1461)
HNAHMFAC_01602 8.39e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HNAHMFAC_01603 2.13e-229 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HNAHMFAC_01604 5.77e-81 yugI - - J ko:K07570 - ko00000 general stress protein
HNAHMFAC_01605 3.44e-200 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HNAHMFAC_01606 6.71e-201 - - - I - - - alpha/beta hydrolase fold
HNAHMFAC_01607 2.53e-139 - - - S - - - SNARE associated Golgi protein
HNAHMFAC_01608 3.26e-130 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HNAHMFAC_01609 6.46e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNAHMFAC_01610 4.58e-246 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HNAHMFAC_01611 1e-78 ydeP - - K - - - Transcriptional regulator, HxlR family
HNAHMFAC_01612 1.3e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HNAHMFAC_01613 2.31e-122 - - - K - - - Bacterial regulatory proteins, tetR family
HNAHMFAC_01614 3.76e-145 - - - S - - - NADPH-dependent FMN reductase
HNAHMFAC_01615 4.22e-219 - - - K - - - Helix-turn-helix
HNAHMFAC_01616 1.15e-173 - - - S - - - Putative ABC-transporter type IV
HNAHMFAC_01617 4.37e-79 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HNAHMFAC_01618 1.64e-120 - - - K - - - acetyltransferase
HNAHMFAC_01620 1.58e-203 yvgN - - C - - - Aldo keto reductase
HNAHMFAC_01621 3.97e-311 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HNAHMFAC_01622 7.32e-269 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HNAHMFAC_01623 9.12e-162 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
HNAHMFAC_01624 7.28e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HNAHMFAC_01625 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HNAHMFAC_01626 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
HNAHMFAC_01627 0.0 - - - S - - - TerB-C domain
HNAHMFAC_01628 1.57e-50 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HNAHMFAC_01629 2.16e-106 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HNAHMFAC_01630 2.91e-94 - - - - - - - -
HNAHMFAC_01631 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HNAHMFAC_01632 3.45e-107 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HNAHMFAC_01633 1.24e-312 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HNAHMFAC_01635 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HNAHMFAC_01636 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNAHMFAC_01637 1.11e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNAHMFAC_01638 1.99e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNAHMFAC_01639 1.2e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNAHMFAC_01640 1.03e-301 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
HNAHMFAC_01641 6.09e-199 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HNAHMFAC_01642 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNAHMFAC_01643 5.61e-98 - - - K - - - LytTr DNA-binding domain
HNAHMFAC_01644 1.43e-95 - - - S - - - Protein of unknown function (DUF3021)
HNAHMFAC_01645 9.59e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HNAHMFAC_01646 1.6e-119 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HNAHMFAC_01647 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNAHMFAC_01648 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HNAHMFAC_01649 3.54e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNAHMFAC_01650 1.69e-213 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNAHMFAC_01651 5.71e-116 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HNAHMFAC_01652 7.9e-269 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HNAHMFAC_01653 9.54e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNAHMFAC_01654 8.88e-144 yqeK - - H - - - Hydrolase, HD family
HNAHMFAC_01655 4.36e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNAHMFAC_01656 2.8e-277 ylbM - - S - - - Belongs to the UPF0348 family
HNAHMFAC_01657 5.83e-118 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HNAHMFAC_01658 1.89e-169 csrR - - K - - - response regulator
HNAHMFAC_01659 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HNAHMFAC_01660 7.47e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNAHMFAC_01661 2.36e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HNAHMFAC_01662 1.37e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNAHMFAC_01663 1.19e-82 yodB - - K - - - Transcriptional regulator, HxlR family
HNAHMFAC_01664 6.37e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNAHMFAC_01665 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNAHMFAC_01666 1.84e-260 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNAHMFAC_01667 5.34e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNAHMFAC_01668 0.0 - - - S - - - membrane
HNAHMFAC_01669 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HNAHMFAC_01670 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HNAHMFAC_01671 2.1e-113 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNAHMFAC_01672 2.67e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HNAHMFAC_01673 3.31e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HNAHMFAC_01674 4.22e-76 yqhL - - P - - - Rhodanese-like protein
HNAHMFAC_01675 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
HNAHMFAC_01676 2.54e-215 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNAHMFAC_01677 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HNAHMFAC_01678 1.83e-259 - - - EGP - - - Major Facilitator Superfamily
HNAHMFAC_01679 2.49e-188 supH - - S - - - haloacid dehalogenase-like hydrolase
HNAHMFAC_01681 9.41e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
HNAHMFAC_01682 1.76e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HNAHMFAC_01683 4.48e-278 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HNAHMFAC_01684 9.79e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HNAHMFAC_01685 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNAHMFAC_01686 6.33e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HNAHMFAC_01687 3.92e-146 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HNAHMFAC_01688 3.77e-113 - - - - - - - -
HNAHMFAC_01689 4.01e-100 - - - - - - - -
HNAHMFAC_01690 5.48e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
HNAHMFAC_01691 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNAHMFAC_01692 2.17e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HNAHMFAC_01693 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HNAHMFAC_01694 1.02e-34 - - - - - - - -
HNAHMFAC_01695 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HNAHMFAC_01696 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNAHMFAC_01697 3.12e-224 - - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_01699 3.33e-16 - - - - - - - -
HNAHMFAC_01700 2.33e-131 int3 - - L - - - Belongs to the 'phage' integrase family
HNAHMFAC_01702 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAHMFAC_01703 2.22e-277 yfmL - - L - - - DEAD DEAH box helicase
HNAHMFAC_01704 1.34e-175 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HNAHMFAC_01705 6.91e-297 - - - E ko:K03294 - ko00000 amino acid
HNAHMFAC_01706 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HNAHMFAC_01707 4.03e-301 yhdP - - S - - - Transporter associated domain
HNAHMFAC_01708 2.93e-165 - - - - - - - -
HNAHMFAC_01709 3.82e-148 - - - C - - - nitroreductase
HNAHMFAC_01710 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HNAHMFAC_01711 1.34e-115 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HNAHMFAC_01712 7.52e-147 - - - V - - - ABC transporter transmembrane region
HNAHMFAC_01714 1.39e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
HNAHMFAC_01715 3.96e-224 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HNAHMFAC_01716 7.73e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HNAHMFAC_01717 4.72e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNAHMFAC_01718 1.98e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HNAHMFAC_01719 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HNAHMFAC_01720 2.99e-77 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNAHMFAC_01721 8.28e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HNAHMFAC_01722 1.98e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNAHMFAC_01723 4.68e-191 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNAHMFAC_01724 1.19e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HNAHMFAC_01725 8.44e-217 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HNAHMFAC_01726 5.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HNAHMFAC_01727 3.23e-124 - - - K - - - Acetyltransferase (GNAT) domain
HNAHMFAC_01728 2.67e-165 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01729 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HNAHMFAC_01730 2.25e-206 - - - S - - - Phospholipase, patatin family
HNAHMFAC_01731 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HNAHMFAC_01733 6.77e-71 - - - S - - - Enterocin A Immunity
HNAHMFAC_01737 2.98e-287 - - - S - - - CAAX protease self-immunity
HNAHMFAC_01738 1.09e-61 - - - S - - - Enterocin A Immunity
HNAHMFAC_01740 4.72e-134 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HNAHMFAC_01741 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HNAHMFAC_01743 1.5e-231 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HNAHMFAC_01744 1.86e-162 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HNAHMFAC_01745 1.73e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HNAHMFAC_01746 1.22e-85 - - - S - - - Domain of unknown function (DUF956)
HNAHMFAC_01747 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HNAHMFAC_01748 2.21e-296 yifK - - E ko:K03293 - ko00000 Amino acid permease
HNAHMFAC_01749 2.81e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HNAHMFAC_01750 4.22e-304 - - - E - - - amino acid
HNAHMFAC_01751 9.96e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HNAHMFAC_01752 5.49e-207 - - - EG - - - EamA-like transporter family
HNAHMFAC_01753 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HNAHMFAC_01754 5.7e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HNAHMFAC_01755 6.61e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HNAHMFAC_01756 3.54e-182 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HNAHMFAC_01757 1.29e-235 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HNAHMFAC_01758 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HNAHMFAC_01759 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HNAHMFAC_01760 6.45e-47 - - - - - - - -
HNAHMFAC_01761 8.26e-250 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_01762 1.03e-240 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HNAHMFAC_01763 2.96e-116 ymdB - - S - - - Macro domain protein
HNAHMFAC_01764 0.0 - - - V - - - ABC transporter transmembrane region
HNAHMFAC_01765 1.19e-160 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HNAHMFAC_01766 8.68e-178 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HNAHMFAC_01767 3.13e-99 - - - EGP - - - Major Facilitator Superfamily
HNAHMFAC_01768 1.29e-199 - - - - - - - -
HNAHMFAC_01769 3.16e-93 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
HNAHMFAC_01770 6.97e-198 - - - C - - - Domain of unknown function (DUF4931)
HNAHMFAC_01771 2.31e-195 - - - K - - - Helix-turn-helix domain, rpiR family
HNAHMFAC_01772 3.78e-170 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HNAHMFAC_01773 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HNAHMFAC_01774 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAHMFAC_01775 2.03e-197 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNAHMFAC_01776 1.17e-152 - - - - - - - -
HNAHMFAC_01777 1.88e-66 - - - - - - - -
HNAHMFAC_01778 2.29e-175 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HNAHMFAC_01779 3.92e-173 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HNAHMFAC_01780 4.02e-145 - - - G - - - Phosphoglycerate mutase family
HNAHMFAC_01781 6.22e-140 - - - G - - - phosphoglycerate mutase
HNAHMFAC_01782 5.22e-108 - - - K - - - Bacterial regulatory proteins, tetR family
HNAHMFAC_01783 7.64e-230 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HNAHMFAC_01784 3.65e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01785 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HNAHMFAC_01786 3.9e-50 - - - - - - - -
HNAHMFAC_01787 7.43e-136 - - - K - - - WHG domain
HNAHMFAC_01788 2.22e-125 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HNAHMFAC_01789 4.45e-128 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HNAHMFAC_01790 2.89e-252 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HNAHMFAC_01791 1.62e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HNAHMFAC_01792 3.37e-221 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HNAHMFAC_01793 4.31e-123 cvpA - - S - - - Colicin V production protein
HNAHMFAC_01794 5.02e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HNAHMFAC_01795 4.28e-196 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HNAHMFAC_01796 1.01e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HNAHMFAC_01797 3.67e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HNAHMFAC_01798 7.4e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HNAHMFAC_01799 1.89e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNAHMFAC_01800 4.99e-187 - - - S - - - Protein of unknown function (DUF1129)
HNAHMFAC_01801 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01802 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HNAHMFAC_01803 2.39e-156 vanR - - K - - - response regulator
HNAHMFAC_01804 1.7e-262 - - - T - - - His Kinase A (phosphoacceptor) domain
HNAHMFAC_01805 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNAHMFAC_01806 7.48e-184 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HNAHMFAC_01807 2.43e-209 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HNAHMFAC_01808 2.34e-283 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HNAHMFAC_01809 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HNAHMFAC_01810 4.07e-134 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HNAHMFAC_01811 5.13e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HNAHMFAC_01812 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)