Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NPHNICFO_00001	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPHNICFO_00002	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
NPHNICFO_00003	9.68e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPHNICFO_00004	6.12e-313	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_00005	2.11e-53	-	-	-	-	-	-	-	-
NPHNICFO_00006	6.86e-276	-	-	-	E	-	-	-	Major Facilitator Superfamily
NPHNICFO_00007	6.15e-190	pbpX2	-	-	V	-	-	-	Beta-lactamase
NPHNICFO_00008	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPHNICFO_00009	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHNICFO_00010	1.99e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NPHNICFO_00011	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHNICFO_00012	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NPHNICFO_00013	6.13e-52	-	-	-	-	-	-	-	-
NPHNICFO_00014	2.57e-272	-	-	-	S	-	-	-	Membrane
NPHNICFO_00016	1.18e-78	-	-	-	-	-	-	-	-
NPHNICFO_00017	1.88e-66	-	-	-	-	-	-	-	-
NPHNICFO_00018	5.45e-61	-	-	-	-	-	-	-	-
NPHNICFO_00019	1.66e-111	ykuL	-	-	S	-	-	-	(CBS) domain
NPHNICFO_00020	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NPHNICFO_00021	1.19e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
NPHNICFO_00022	1.81e-141	-	-	-	S	-	-	-	Putative adhesin
NPHNICFO_00023	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NPHNICFO_00024	2.24e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPHNICFO_00025	2.33e-47	-	-	-	-	-	-	-	-
NPHNICFO_00026	2.07e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPHNICFO_00027	1.18e-200	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
NPHNICFO_00028	7.06e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
NPHNICFO_00029	2.11e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPHNICFO_00032	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NPHNICFO_00033	1.86e-124	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NPHNICFO_00034	4.83e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPHNICFO_00035	3.18e-261	-	-	-	S	-	-	-	DUF218 domain
NPHNICFO_00036	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00037	4.53e-90	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NPHNICFO_00038	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NPHNICFO_00039	1.9e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NPHNICFO_00040	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPHNICFO_00041	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPHNICFO_00042	4.96e-226	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NPHNICFO_00043	1.21e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
NPHNICFO_00044	1.83e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
NPHNICFO_00045	5.87e-195	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPHNICFO_00046	2.55e-247	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
NPHNICFO_00047	1.29e-204	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPHNICFO_00048	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_00049	6.53e-170	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPHNICFO_00050	8.84e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
NPHNICFO_00051	9.42e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPHNICFO_00052	8.43e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
NPHNICFO_00053	4e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
NPHNICFO_00054	2.33e-301	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NPHNICFO_00055	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPHNICFO_00056	7.38e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPHNICFO_00057	9.81e-297	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPHNICFO_00058	1.38e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPHNICFO_00059	5.36e-102	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
NPHNICFO_00060	7.23e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPHNICFO_00061	5.36e-114	-	-	-	-	-	-	-	-
NPHNICFO_00062	7.04e-121	-	-	-	-	-	-	-	-
NPHNICFO_00063	4.11e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
NPHNICFO_00064	6.19e-86	-	-	-	S	-	-	-	Cupredoxin-like domain
NPHNICFO_00065	7.67e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
NPHNICFO_00066	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPHNICFO_00067	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
NPHNICFO_00068	1.95e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPHNICFO_00069	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NPHNICFO_00070	5.82e-136	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPHNICFO_00071	8.72e-160	-	-	-	S	-	-	-	Peptidase_C39 like family
NPHNICFO_00072	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPHNICFO_00073	1.51e-152	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NPHNICFO_00075	6.13e-296	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPHNICFO_00076	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPHNICFO_00077	3.25e-185	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPHNICFO_00078	2.81e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NPHNICFO_00079	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPHNICFO_00080	2.04e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPHNICFO_00081	1.65e-69	-	-	-	-	-	-	-	-
NPHNICFO_00082	9.27e-36	-	-	-	-	-	-	-	-
NPHNICFO_00083	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
NPHNICFO_00084	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NPHNICFO_00085	1.89e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00086	0.0	-	-	-	E	-	-	-	Amino Acid
NPHNICFO_00087	3.49e-159	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NPHNICFO_00088	3.22e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NPHNICFO_00089	2.79e-178	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPHNICFO_00091	6.96e-301	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPHNICFO_00092	8.72e-301	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPHNICFO_00093	1.22e-210	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NPHNICFO_00094	1.18e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NPHNICFO_00095	1.87e-58	-	-	-	-	-	-	-	-
NPHNICFO_00096	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
NPHNICFO_00097	1.91e-143	-	-	-	-	-	-	-	-
NPHNICFO_00098	1.35e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NPHNICFO_00099	4.31e-231	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPHNICFO_00100	6.79e-105	-	-	-	-	-	-	-	-
NPHNICFO_00101	7.58e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPHNICFO_00102	1.05e-53	-	-	-	-	-	-	-	-
NPHNICFO_00103	2.22e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NPHNICFO_00104	1.55e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPHNICFO_00105	0.0	-	-	-	S	-	-	-	ABC transporter
NPHNICFO_00106	2.71e-81	-	-	-	-	-	-	-	-
NPHNICFO_00107	6.06e-54	-	-	-	-	-	-	-	-
NPHNICFO_00108	3.49e-270	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPHNICFO_00109	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NPHNICFO_00110	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NPHNICFO_00111	1.03e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NPHNICFO_00112	1.56e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPHNICFO_00113	2.74e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPHNICFO_00114	1.07e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NPHNICFO_00115	2.58e-181	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
NPHNICFO_00116	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NPHNICFO_00117	4.12e-94	-	-	-	S	-	-	-	YSIRK type signal peptide
NPHNICFO_00118	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NPHNICFO_00119	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPHNICFO_00120	1.38e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NPHNICFO_00121	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NPHNICFO_00122	2.34e-283	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPHNICFO_00123	3.76e-213	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00124	3.17e-185	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NPHNICFO_00125	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPHNICFO_00126	3.35e-269	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NPHNICFO_00127	2.39e-156	vanR	-	-	K	-	-	-	response regulator
NPHNICFO_00128	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPHNICFO_00129	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00130	4.65e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NPHNICFO_00131	1.89e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPHNICFO_00132	7.4e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NPHNICFO_00133	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPHNICFO_00134	3.52e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NPHNICFO_00135	7.73e-199	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPHNICFO_00136	1.75e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NPHNICFO_00137	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
NPHNICFO_00138	3.27e-228	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPHNICFO_00139	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPHNICFO_00140	7.72e-257	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
NPHNICFO_00141	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NPHNICFO_00142	2.22e-125	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NPHNICFO_00143	1.45e-142	-	-	-	K	-	-	-	WHG domain
NPHNICFO_00144	1.36e-50	-	-	-	-	-	-	-	-
NPHNICFO_00145	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPHNICFO_00146	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_00147	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_00148	6.94e-201	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPHNICFO_00149	5.63e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00150	5.03e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NPHNICFO_00151	5.71e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPHNICFO_00152	4.06e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
NPHNICFO_00153	5.95e-147	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NPHNICFO_00154	6.89e-180	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
NPHNICFO_00155	1.29e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NPHNICFO_00156	9.32e-67	-	-	-	-	-	-	-	-
NPHNICFO_00157	2.6e-165	-	-	-	-	-	-	-	-
NPHNICFO_00158	2.16e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NPHNICFO_00159	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_00160	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NPHNICFO_00161	2.14e-185	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NPHNICFO_00162	6.9e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPHNICFO_00163	8.83e-201	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
NPHNICFO_00164	3.16e-93	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
NPHNICFO_00165	4.69e-202	-	-	-	-	-	-	-	-
NPHNICFO_00166	3.13e-99	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPHNICFO_00167	8.68e-178	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPHNICFO_00168	2.06e-161	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NPHNICFO_00169	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NPHNICFO_00170	1.86e-119	ymdB	-	-	S	-	-	-	Macro domain protein
NPHNICFO_00171	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_00172	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NPHNICFO_00173	1.57e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPHNICFO_00174	1.7e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPHNICFO_00175	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPHNICFO_00176	3.43e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NPHNICFO_00177	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPHNICFO_00178	2e-209	-	-	-	EG	-	-	-	EamA-like transporter family
NPHNICFO_00179	4.41e-247	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NPHNICFO_00180	6.26e-306	-	-	-	E	-	-	-	amino acid
NPHNICFO_00181	2.51e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NPHNICFO_00182	2.21e-296	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPHNICFO_00183	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPHNICFO_00184	8.6e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
NPHNICFO_00185	3.64e-221	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NPHNICFO_00186	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NPHNICFO_00187	8.1e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPHNICFO_00189	4.71e-285	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
NPHNICFO_00190	1.95e-291	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPHNICFO_00192	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NPHNICFO_00194	8.83e-112	-	-	-	S	-	-	-	Putative adhesin
NPHNICFO_00195	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_00196	1.49e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NPHNICFO_00197	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPHNICFO_00198	2.91e-86	-	-	-	-	-	-	-	-
NPHNICFO_00199	2.28e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_00200	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_00201	3.16e-193	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_00202	6.35e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00203	3.27e-190	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_00204	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
NPHNICFO_00205	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00206	6e-83	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NPHNICFO_00207	3.44e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
NPHNICFO_00208	5.06e-280	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NPHNICFO_00209	0.0	-	-	-	E	-	-	-	Peptidase family C69
NPHNICFO_00210	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NPHNICFO_00211	8.36e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPHNICFO_00212	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPHNICFO_00213	1.01e-95	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NPHNICFO_00214	2.4e-194	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NPHNICFO_00215	5.6e-162	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NPHNICFO_00216	2.99e-114	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPHNICFO_00217	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NPHNICFO_00218	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NPHNICFO_00219	0.0	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_00220	1.26e-214	-	2.7.1.85	-	GK	ko:K18673	-	ko00000,ko01000	ROK family
NPHNICFO_00221	1.59e-265	xylR	-	-	GK	-	-	-	ROK family
NPHNICFO_00222	2.87e-306	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_00223	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
NPHNICFO_00224	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NPHNICFO_00225	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
NPHNICFO_00226	2.44e-166	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NPHNICFO_00227	1.29e-150	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00229	4.37e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
NPHNICFO_00230	1.2e-49	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NPHNICFO_00232	3.06e-117	-	-	-	-	-	-	-	-
NPHNICFO_00233	1.11e-91	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPHNICFO_00234	5.01e-45	-	-	-	-	-	-	-	-
NPHNICFO_00235	1.62e-277	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
NPHNICFO_00236	0.0	-	-	-	E	-	-	-	amino acid
NPHNICFO_00237	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
NPHNICFO_00238	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPHNICFO_00239	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NPHNICFO_00240	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
NPHNICFO_00241	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPHNICFO_00242	0.0	-	-	-	E	-	-	-	Phospholipase B
NPHNICFO_00243	1.99e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
NPHNICFO_00244	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NPHNICFO_00245	1.26e-117	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
NPHNICFO_00246	6.14e-258	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NPHNICFO_00247	5.58e-108	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_00248	1.18e-308	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NPHNICFO_00249	8.84e-206	-	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_00250	1.15e-192	-	-	-	S	-	-	-	hydrolase
NPHNICFO_00251	1.74e-113	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
NPHNICFO_00252	4.87e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
NPHNICFO_00253	8.41e-260	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NPHNICFO_00254	5.22e-102	-	-	-	K	-	-	-	acetyltransferase
NPHNICFO_00255	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NPHNICFO_00256	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NPHNICFO_00257	9.83e-185	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPHNICFO_00258	1.28e-181	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
NPHNICFO_00259	5.06e-209	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPHNICFO_00260	2.89e-135	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NPHNICFO_00261	8.91e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
NPHNICFO_00262	2.25e-283	-	-	-	P	-	-	-	Voltage gated chloride channel
NPHNICFO_00263	5.09e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NPHNICFO_00264	7.79e-112	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NPHNICFO_00265	0.0	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NPHNICFO_00266	6.93e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
NPHNICFO_00267	2.33e-165	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
NPHNICFO_00268	1.06e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHNICFO_00270	2.29e-64	-	-	-	-	-	-	-	-
NPHNICFO_00271	3.79e-221	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NPHNICFO_00272	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NPHNICFO_00273	9.66e-221	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPHNICFO_00274	1.14e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPHNICFO_00275	1.02e-176	-	-	-	-	-	-	-	-
NPHNICFO_00276	4.15e-280	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
NPHNICFO_00277	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPHNICFO_00278	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NPHNICFO_00279	1.19e-150	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NPHNICFO_00280	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
NPHNICFO_00281	2.13e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPHNICFO_00286	1.9e-259	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
NPHNICFO_00287	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPHNICFO_00288	4.92e-290	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPHNICFO_00289	4.62e-183	-	-	-	-	-	-	-	-
NPHNICFO_00290	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NPHNICFO_00291	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPHNICFO_00292	0.0	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NPHNICFO_00293	1.58e-199	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPHNICFO_00294	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPHNICFO_00295	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NPHNICFO_00296	7.27e-266	-	-	-	M	-	-	-	Glycosyl transferases group 1
NPHNICFO_00297	6.86e-174	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPHNICFO_00298	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
NPHNICFO_00299	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NPHNICFO_00300	1.84e-244	-	-	-	-	-	-	-	-
NPHNICFO_00301	1.19e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
NPHNICFO_00304	5.98e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
NPHNICFO_00305	1.21e-45	-	-	-	K	-	-	-	SIS domain
NPHNICFO_00306	2.51e-49	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
NPHNICFO_00309	8.77e-192	-	-	-	I	-	-	-	Acyl-transferase
NPHNICFO_00310	4.36e-200	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
NPHNICFO_00311	8.41e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
NPHNICFO_00312	2.24e-239	-	-	-	M	-	-	-	Glycosyl transferase family 8
NPHNICFO_00313	3.48e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
NPHNICFO_00314	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPHNICFO_00315	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPHNICFO_00316	3.19e-239	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NPHNICFO_00317	5.19e-111	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPHNICFO_00318	8.35e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NPHNICFO_00319	4.14e-176	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPHNICFO_00320	6.9e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPHNICFO_00321	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPHNICFO_00322	3.37e-221	-	-	-	K	-	-	-	LysR substrate binding domain
NPHNICFO_00323	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NPHNICFO_00324	0.0	-	-	-	M	-	-	-	domain protein
NPHNICFO_00325	1.49e-203	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NPHNICFO_00326	7.16e-155	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPHNICFO_00327	3.34e-13	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_00328	3.05e-57	bglP	2.7.1.199, 2.7.1.208, 2.7.1.211	-	G	ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02778,ko:K02779,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NPHNICFO_00329	9.03e-203	-	-	-	EG	-	-	-	EamA-like transporter family
NPHNICFO_00330	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_00331	2.65e-217	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPHNICFO_00332	5.58e-180	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NPHNICFO_00333	4.65e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NPHNICFO_00334	8.61e-89	-	-	-	-	-	-	-	-
NPHNICFO_00335	1.97e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPHNICFO_00336	1.27e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NPHNICFO_00337	7.59e-305	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPHNICFO_00338	1.7e-182	-	-	-	S	-	-	-	PAS domain
NPHNICFO_00339	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
NPHNICFO_00340	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NPHNICFO_00341	6.11e-188	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NPHNICFO_00342	9.55e-118	-	-	-	-	-	-	-	-
NPHNICFO_00343	9.28e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPHNICFO_00344	2.42e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPHNICFO_00345	0.0	-	-	-	GM	ko:K13732	ko05100,map05100	ko00000,ko00001	domain, Protein
NPHNICFO_00346	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
NPHNICFO_00347	1.18e-274	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
NPHNICFO_00348	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
NPHNICFO_00349	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
NPHNICFO_00350	2.26e-208	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
NPHNICFO_00351	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPHNICFO_00352	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPHNICFO_00353	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPHNICFO_00355	5.77e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
NPHNICFO_00356	7.44e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NPHNICFO_00357	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NPHNICFO_00358	3.32e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NPHNICFO_00359	1.2e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPHNICFO_00360	1.45e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NPHNICFO_00361	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPHNICFO_00362	1.39e-74	-	-	-	-	-	-	-	-
NPHNICFO_00363	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NPHNICFO_00364	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NPHNICFO_00365	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
NPHNICFO_00366	4.12e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NPHNICFO_00367	2.55e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPHNICFO_00368	8.01e-66	-	-	-	-	-	-	-	-
NPHNICFO_00369	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPHNICFO_00370	1.21e-177	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NPHNICFO_00371	4.33e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHNICFO_00372	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NPHNICFO_00373	3.6e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPHNICFO_00374	1.23e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPHNICFO_00375	3.65e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NPHNICFO_00376	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPHNICFO_00377	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPHNICFO_00378	1.96e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
NPHNICFO_00379	3.49e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NPHNICFO_00380	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPHNICFO_00381	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NPHNICFO_00382	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPHNICFO_00383	1.96e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPHNICFO_00384	1.24e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NPHNICFO_00385	4.21e-266	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPHNICFO_00386	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPHNICFO_00387	2.39e-75	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPHNICFO_00388	5.68e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPHNICFO_00389	3.1e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPHNICFO_00390	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPHNICFO_00391	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPHNICFO_00392	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
NPHNICFO_00394	9.83e-148	-	-	-	-	-	-	-	-
NPHNICFO_00395	1.53e-18	-	-	-	K	-	-	-	Helix-turn-helix domain
NPHNICFO_00396	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPHNICFO_00397	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPHNICFO_00399	6.76e-168	-	-	-	S	-	-	-	membrane
NPHNICFO_00400	5.72e-104	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPHNICFO_00401	3.54e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPHNICFO_00402	2.38e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NPHNICFO_00403	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPHNICFO_00404	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NPHNICFO_00405	2.13e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPHNICFO_00406	2.32e-109	-	-	-	-	-	-	-	-
NPHNICFO_00407	1.4e-195	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPHNICFO_00408	5.24e-181	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPHNICFO_00409	3.82e-180	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPHNICFO_00410	2.26e-259	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPHNICFO_00411	1.06e-71	-	-	-	-	-	-	-	-
NPHNICFO_00412	1.99e-44	-	-	-	-	-	-	-	-
NPHNICFO_00413	2e-103	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NPHNICFO_00414	7.79e-185	-	-	-	L	-	-	-	oxidized base lesion DNA N-glycosylase activity
NPHNICFO_00415	1.98e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPHNICFO_00416	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPHNICFO_00417	8.5e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHNICFO_00418	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPHNICFO_00419	1.41e-149	-	-	-	-	-	-	-	-
NPHNICFO_00420	3.47e-211	-	-	-	-	-	-	-	-
NPHNICFO_00421	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NPHNICFO_00422	3.01e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPHNICFO_00423	1.83e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NPHNICFO_00424	1.82e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NPHNICFO_00425	1.06e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NPHNICFO_00426	8.09e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NPHNICFO_00427	3.42e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPHNICFO_00428	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NPHNICFO_00429	1.69e-198	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPHNICFO_00430	3.05e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NPHNICFO_00431	1.51e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPHNICFO_00432	1.06e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NPHNICFO_00433	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPHNICFO_00434	6.62e-69	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPHNICFO_00435	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHNICFO_00436	6.08e-112	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPHNICFO_00437	3.56e-68	-	-	-	S	-	-	-	Protein conserved in bacteria
NPHNICFO_00438	2.72e-185	-	-	-	-	-	-	-	-
NPHNICFO_00439	3.9e-30	-	-	-	-	-	-	-	-
NPHNICFO_00440	4.73e-146	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NPHNICFO_00441	3.25e-44	-	-	-	-	-	-	-	-
NPHNICFO_00442	3.28e-183	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
NPHNICFO_00443	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPHNICFO_00444	7.87e-125	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPHNICFO_00445	8.08e-188	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_00446	2.23e-150	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
NPHNICFO_00447	3.38e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPHNICFO_00448	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPHNICFO_00449	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPHNICFO_00450	5.22e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NPHNICFO_00451	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPHNICFO_00452	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPHNICFO_00453	7.71e-255	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPHNICFO_00454	5.84e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
NPHNICFO_00455	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPHNICFO_00456	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NPHNICFO_00457	5.9e-46	-	-	-	-	-	-	-	-
NPHNICFO_00458	1.14e-30	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
NPHNICFO_00459	1.27e-38	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
NPHNICFO_00460	1.39e-180	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHNICFO_00461	5.57e-104	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPHNICFO_00462	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPHNICFO_00463	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPHNICFO_00464	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPHNICFO_00465	3.82e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NPHNICFO_00466	1.66e-246	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPHNICFO_00467	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPHNICFO_00468	5.61e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPHNICFO_00469	3.35e-213	-	-	-	S	-	-	-	glycosyl transferase family 2
NPHNICFO_00470	2.31e-35	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NPHNICFO_00471	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPHNICFO_00472	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPHNICFO_00473	2.18e-47	yabO	-	-	J	-	-	-	S4 domain protein
NPHNICFO_00474	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NPHNICFO_00475	4.65e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
NPHNICFO_00476	2.07e-312	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPHNICFO_00477	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPHNICFO_00478	0.0	-	-	-	S	-	-	-	membrane
NPHNICFO_00479	0.0	-	-	-	S	-	-	-	membrane
NPHNICFO_00480	1.65e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPHNICFO_00481	3.21e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPHNICFO_00482	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NPHNICFO_00485	2.94e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPHNICFO_00486	1.21e-65	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
NPHNICFO_00487	7.78e-125	-	-	-	S	-	-	-	Membrane
NPHNICFO_00488	4.65e-184	-	-	-	S	-	-	-	Domain of unknown function DUF1829
NPHNICFO_00489	3.06e-108	-	-	-	-	-	-	-	-
NPHNICFO_00490	9.06e-102	-	-	-	S	-	-	-	Pfam:Peptidase_M78
NPHNICFO_00491	3.29e-75	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NPHNICFO_00492	3.19e-41	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPHNICFO_00493	1.45e-181	-	-	-	K	ko:K07741	-	ko00000	Phage antirepressor protein
NPHNICFO_00494	8.13e-62	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NPHNICFO_00496	2.67e-43	-	-	-	-	-	-	-	-
NPHNICFO_00497	1.04e-27	-	-	-	-	-	-	-	-
NPHNICFO_00498	6.83e-20	-	-	-	-	-	-	-	-
NPHNICFO_00499	4.59e-86	-	-	-	-	-	-	-	-
NPHNICFO_00500	7.53e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
NPHNICFO_00501	2.39e-190	-	-	-	S	-	-	-	ERF superfamily
NPHNICFO_00502	9.24e-162	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NPHNICFO_00503	1.63e-56	-	-	-	-	-	-	-	-
NPHNICFO_00505	2.07e-200	-	-	-	K	ko:K07741	-	ko00000	Phage antirepressor protein KilAC domain
NPHNICFO_00507	4.96e-16	-	-	-	-	-	-	-	-
NPHNICFO_00508	1.44e-113	-	-	-	-	-	-	-	-
NPHNICFO_00512	2.42e-263	-	-	-	K	-	-	-	acetyltransferase
NPHNICFO_00513	5.49e-85	-	-	-	S	-	-	-	ASCH
NPHNICFO_00514	8.12e-135	-	-	-	-	-	-	-	-
NPHNICFO_00515	3.44e-202	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NPHNICFO_00516	0.0	-	-	-	S	-	-	-	Terminase-like family
NPHNICFO_00517	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NPHNICFO_00518	3.92e-60	-	-	-	S	-	-	-	Cysteine protease Prp
NPHNICFO_00519	5.03e-256	-	-	-	S	-	-	-	Phage Mu protein F like protein
NPHNICFO_00520	1.44e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NPHNICFO_00521	5.17e-83	-	-	-	-	-	-	-	-
NPHNICFO_00522	5.39e-250	-	-	-	S	-	-	-	Phage major capsid protein E
NPHNICFO_00523	5.52e-63	-	-	-	-	-	-	-	-
NPHNICFO_00524	1.1e-82	-	-	-	-	-	-	-	-
NPHNICFO_00525	1.56e-127	-	-	-	-	-	-	-	-
NPHNICFO_00526	2.27e-82	-	-	-	-	-	-	-	-
NPHNICFO_00527	7.39e-108	-	-	-	S	-	-	-	Phage tail tube protein, TTP
NPHNICFO_00528	1.85e-90	-	-	-	-	-	-	-	-
NPHNICFO_00529	6.96e-64	-	-	-	-	-	-	-	-
NPHNICFO_00530	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NPHNICFO_00531	1.97e-81	-	-	-	-	-	-	-	-
NPHNICFO_00532	0.0	-	-	-	LM	-	-	-	gp58-like protein
NPHNICFO_00534	3.08e-52	-	-	-	-	-	-	-	-
NPHNICFO_00535	2.44e-90	-	-	-	-	-	-	-	-
NPHNICFO_00536	2.76e-50	-	-	-	-	-	-	-	-
NPHNICFO_00538	1.19e-231	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPHNICFO_00540	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPHNICFO_00541	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHNICFO_00542	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHNICFO_00543	8.18e-141	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
NPHNICFO_00544	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPHNICFO_00545	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPHNICFO_00546	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPHNICFO_00547	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NPHNICFO_00548	8.75e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPHNICFO_00549	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NPHNICFO_00550	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPHNICFO_00551	1.99e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPHNICFO_00552	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPHNICFO_00553	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPHNICFO_00554	1.29e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPHNICFO_00555	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPHNICFO_00556	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NPHNICFO_00557	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPHNICFO_00558	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPHNICFO_00559	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPHNICFO_00560	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPHNICFO_00561	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHNICFO_00562	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPHNICFO_00563	3.04e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPHNICFO_00564	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPHNICFO_00565	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPHNICFO_00566	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NPHNICFO_00567	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPHNICFO_00568	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPHNICFO_00569	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPHNICFO_00570	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPHNICFO_00571	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NPHNICFO_00572	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPHNICFO_00573	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPHNICFO_00574	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHNICFO_00575	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NPHNICFO_00576	1.63e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHNICFO_00577	4.92e-209	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHNICFO_00578	7.09e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHNICFO_00579	9.48e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPHNICFO_00580	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPHNICFO_00581	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NPHNICFO_00583	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
NPHNICFO_00584	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NPHNICFO_00585	2.49e-91	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
NPHNICFO_00589	4.99e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPHNICFO_00590	6.42e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NPHNICFO_00591	1.76e-175	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NPHNICFO_00592	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NPHNICFO_00593	1.25e-107	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
NPHNICFO_00594	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NPHNICFO_00596	3.58e-167	-	-	-	S	-	-	-	Alpha beta hydrolase
NPHNICFO_00597	3.53e-14	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
NPHNICFO_00598	6.31e-252	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPHNICFO_00599	9.58e-25	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPHNICFO_00600	9.11e-77	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPHNICFO_00601	2.44e-209	-	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_00602	1.05e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NPHNICFO_00603	2.6e-96	-	-	-	-	-	-	-	-
NPHNICFO_00605	5.82e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NPHNICFO_00606	1.2e-136	-	-	-	K	-	-	-	LysR substrate binding domain
NPHNICFO_00607	2.49e-230	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPHNICFO_00608	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPHNICFO_00609	1.9e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPHNICFO_00610	3.25e-223	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
NPHNICFO_00611	9.49e-317	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPHNICFO_00612	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPHNICFO_00613	1.51e-199	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NPHNICFO_00614	1.89e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHNICFO_00615	8.49e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPHNICFO_00616	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NPHNICFO_00617	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NPHNICFO_00618	7.72e-195	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NPHNICFO_00619	2.78e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NPHNICFO_00620	2.86e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPHNICFO_00621	4.7e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPHNICFO_00622	1.46e-134	-	-	-	J	ko:K10716	-	ko00000,ko02000	Ion transport protein
NPHNICFO_00623	5.77e-193	-	-	-	-	-	-	-	-
NPHNICFO_00624	1e-242	-	-	-	S	-	-	-	SIR2-like domain
NPHNICFO_00625	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NPHNICFO_00626	2.89e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NPHNICFO_00627	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPHNICFO_00628	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NPHNICFO_00629	6.93e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NPHNICFO_00630	1.78e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NPHNICFO_00631	2.31e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPHNICFO_00632	1.08e-117	-	-	-	M	-	-	-	Lysin motif
NPHNICFO_00633	4.82e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPHNICFO_00634	1.59e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPHNICFO_00635	1.23e-172	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPHNICFO_00636	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
NPHNICFO_00637	3.91e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NPHNICFO_00638	3.33e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NPHNICFO_00639	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NPHNICFO_00640	1.69e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPHNICFO_00641	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPHNICFO_00642	7.45e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NPHNICFO_00643	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NPHNICFO_00644	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NPHNICFO_00645	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NPHNICFO_00646	7.14e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPHNICFO_00647	1.68e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPHNICFO_00648	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NPHNICFO_00649	7.6e-306	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPHNICFO_00650	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPHNICFO_00651	4.99e-223	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
NPHNICFO_00652	8.71e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NPHNICFO_00653	1.15e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NPHNICFO_00654	5.48e-150	-	-	-	GM	-	-	-	NmrA-like family
NPHNICFO_00655	1.06e-314	yagE	-	-	E	-	-	-	amino acid
NPHNICFO_00656	2.03e-09	-	-	-	-	-	-	-	-
NPHNICFO_00657	8.94e-161	-	-	-	S	-	-	-	Rib/alpha-like repeat
NPHNICFO_00658	6.93e-88	-	-	-	S	-	-	-	Domain of unknown function DUF1828
NPHNICFO_00659	1.48e-90	-	-	-	-	-	-	-	-
NPHNICFO_00660	3.26e-93	-	-	-	-	-	-	-	-
NPHNICFO_00661	4.42e-105	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NPHNICFO_00662	5.83e-172	-	-	-	-	-	-	-	-
NPHNICFO_00664	1.46e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
NPHNICFO_00665	0.0	-	-	-	L	-	-	-	UvrD-like helicase C-terminal domain
NPHNICFO_00666	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
NPHNICFO_00667	1.59e-266	-	-	-	K	-	-	-	IrrE N-terminal-like domain
NPHNICFO_00668	1.62e-178	-	-	-	-	-	-	-	-
NPHNICFO_00670	7.57e-244	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPHNICFO_00671	1.21e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPHNICFO_00672	1.36e-213	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPHNICFO_00673	9.49e-267	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPHNICFO_00674	2.17e-288	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
NPHNICFO_00675	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
NPHNICFO_00676	6.11e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF4411)
NPHNICFO_00677	1.35e-284	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NPHNICFO_00680	6.6e-47	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHNICFO_00681	1.42e-90	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHNICFO_00682	6.46e-83	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NPHNICFO_00685	1.36e-227	-	-	-	S	-	-	-	Acyltransferase family
NPHNICFO_00686	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NPHNICFO_00687	7.13e-224	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
NPHNICFO_00688	1.06e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NPHNICFO_00689	1.31e-286	-	-	-	-	-	-	-	-
NPHNICFO_00690	6.11e-228	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
NPHNICFO_00691	1.79e-267	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPHNICFO_00692	1.31e-269	-	-	-	M	-	-	-	Glycosyl transferases group 1
NPHNICFO_00693	4.04e-265	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPHNICFO_00694	4.35e-192	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NPHNICFO_00695	2.41e-156	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
NPHNICFO_00696	1.06e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NPHNICFO_00697	3.88e-163	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NPHNICFO_00698	3.14e-195	epsB	-	-	M	-	-	-	biosynthesis protein
NPHNICFO_00699	1.17e-209	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPHNICFO_00700	1.32e-106	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NPHNICFO_00701	1.12e-211	-	-	-	-	-	-	-	-
NPHNICFO_00702	2.93e-158	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NPHNICFO_00703	6.51e-288	-	-	-	-	-	-	-	-
NPHNICFO_00704	9.34e-113	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NPHNICFO_00705	1.76e-152	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NPHNICFO_00707	1.1e-108	-	-	-	-	-	-	-	-
NPHNICFO_00708	1.62e-115	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHNICFO_00709	5.34e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NPHNICFO_00710	4.32e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPHNICFO_00711	2.09e-277	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPHNICFO_00712	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPHNICFO_00713	5.74e-206	-	-	-	-	-	-	-	-
NPHNICFO_00714	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHNICFO_00715	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPHNICFO_00716	1.27e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NPHNICFO_00717	8.31e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NPHNICFO_00718	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NPHNICFO_00719	3.36e-220	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NPHNICFO_00720	7.81e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NPHNICFO_00721	7.21e-237	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NPHNICFO_00722	5.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPHNICFO_00723	8.64e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NPHNICFO_00724	4e-66	ylbG	-	-	S	-	-	-	UPF0298 protein
NPHNICFO_00725	1.36e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPHNICFO_00726	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NPHNICFO_00727	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPHNICFO_00728	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NPHNICFO_00729	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHNICFO_00730	8.34e-228	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPHNICFO_00731	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPHNICFO_00732	3.57e-151	-	-	-	S	-	-	-	repeat protein
NPHNICFO_00733	5.5e-162	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
NPHNICFO_00734	9.01e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPHNICFO_00735	1.27e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NPHNICFO_00736	3.68e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPHNICFO_00737	1.02e-164	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPHNICFO_00738	6.32e-52	-	-	-	-	-	-	-	-
NPHNICFO_00739	1.81e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NPHNICFO_00740	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NPHNICFO_00741	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPHNICFO_00742	3.14e-162	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NPHNICFO_00743	1.39e-187	ylmH	-	-	S	-	-	-	S4 domain protein
NPHNICFO_00744	1.36e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NPHNICFO_00745	9.26e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPHNICFO_00746	3.29e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPHNICFO_00747	5.2e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPHNICFO_00748	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPHNICFO_00749	9.56e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPHNICFO_00750	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPHNICFO_00751	9e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPHNICFO_00752	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPHNICFO_00753	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NPHNICFO_00754	1.42e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPHNICFO_00755	1.89e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NPHNICFO_00756	2.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
NPHNICFO_00757	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NPHNICFO_00758	3.99e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
NPHNICFO_00759	1.17e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NPHNICFO_00760	3.11e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NPHNICFO_00761	9.17e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NPHNICFO_00762	2.31e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NPHNICFO_00763	8.14e-302	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPHNICFO_00764	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPHNICFO_00765	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPHNICFO_00766	1.47e-234	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
NPHNICFO_00767	3.13e-159	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPHNICFO_00768	1.09e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPHNICFO_00769	6.1e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPHNICFO_00770	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPHNICFO_00772	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPHNICFO_00773	1.06e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPHNICFO_00774	2.88e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPHNICFO_00775	9.34e-08	-	-	-	-	-	-	-	-
NPHNICFO_00776	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
NPHNICFO_00777	1.3e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NPHNICFO_00778	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NPHNICFO_00779	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NPHNICFO_00780	3.34e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NPHNICFO_00781	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NPHNICFO_00782	3.07e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NPHNICFO_00783	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NPHNICFO_00784	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPHNICFO_00785	1.21e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPHNICFO_00786	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPHNICFO_00787	1.13e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHNICFO_00788	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPHNICFO_00789	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHNICFO_00790	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NPHNICFO_00791	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPHNICFO_00792	8.5e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPHNICFO_00793	5.31e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPHNICFO_00794	4.43e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPHNICFO_00795	8.2e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NPHNICFO_00796	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
NPHNICFO_00797	8.25e-249	ampC	-	-	V	-	-	-	Beta-lactamase
NPHNICFO_00800	6.02e-94	-	-	-	-	-	-	-	-
NPHNICFO_00801	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NPHNICFO_00802	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPHNICFO_00803	9.16e-138	vanZ	-	-	V	-	-	-	VanZ like family
NPHNICFO_00804	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHNICFO_00805	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NPHNICFO_00806	1.89e-166	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NPHNICFO_00807	2.29e-88	-	-	-	S	-	-	-	SdpI/YhfL protein family
NPHNICFO_00808	3.75e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPHNICFO_00809	8.46e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPHNICFO_00810	8.27e-133	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NPHNICFO_00811	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NPHNICFO_00813	1.66e-289	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHNICFO_00814	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NPHNICFO_00815	8.81e-114	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
NPHNICFO_00817	3.97e-77	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
NPHNICFO_00818	9.23e-55	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
NPHNICFO_00819	2.19e-225	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NPHNICFO_00820	5.45e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NPHNICFO_00821	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NPHNICFO_00822	9.17e-126	-	-	-	S	-	-	-	VanZ like family
NPHNICFO_00823	4.49e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPHNICFO_00824	8.84e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPHNICFO_00825	5.08e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NPHNICFO_00826	1.25e-150	-	-	-	-	-	-	-	-
NPHNICFO_00827	3.89e-285	-	-	-	S	-	-	-	Putative adhesin
NPHNICFO_00828	3.02e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHNICFO_00829	3.02e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHNICFO_00830	1.39e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPHNICFO_00831	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPHNICFO_00832	1.33e-225	ybbR	-	-	S	-	-	-	YbbR-like protein
NPHNICFO_00833	6.38e-197	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPHNICFO_00834	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_00835	2.65e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_00836	2.51e-172	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_00837	1.46e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPHNICFO_00838	1.12e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NPHNICFO_00839	2.23e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPHNICFO_00840	1.75e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NPHNICFO_00841	4.47e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NPHNICFO_00842	1.02e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPHNICFO_00843	6.67e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPHNICFO_00844	2.08e-122	-	-	-	-	-	-	-	-
NPHNICFO_00845	4.65e-112	-	-	-	-	-	-	-	-
NPHNICFO_00846	6.82e-139	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
NPHNICFO_00847	1.46e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPHNICFO_00848	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPHNICFO_00849	7.52e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPHNICFO_00850	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPHNICFO_00851	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPHNICFO_00852	4.94e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NPHNICFO_00853	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPHNICFO_00854	3.72e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NPHNICFO_00856	0.0	ycaM	-	-	E	-	-	-	amino acid
NPHNICFO_00857	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPHNICFO_00858	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NPHNICFO_00859	1.54e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NPHNICFO_00860	1.58e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NPHNICFO_00861	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NPHNICFO_00862	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPHNICFO_00863	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPHNICFO_00864	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPHNICFO_00865	1.94e-246	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPHNICFO_00866	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NPHNICFO_00867	1.36e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPHNICFO_00868	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NPHNICFO_00869	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPHNICFO_00870	1.36e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPHNICFO_00871	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NPHNICFO_00872	4.7e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NPHNICFO_00873	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPHNICFO_00874	2.68e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPHNICFO_00875	1.16e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NPHNICFO_00876	2.16e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPHNICFO_00877	1.49e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPHNICFO_00878	3.73e-40	-	-	-	-	-	-	-	-
NPHNICFO_00879	3.56e-235	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPHNICFO_00880	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPHNICFO_00881	3.97e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPHNICFO_00882	5.48e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NPHNICFO_00883	4.57e-288	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NPHNICFO_00884	2.31e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NPHNICFO_00885	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
NPHNICFO_00886	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NPHNICFO_00887	2.99e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPHNICFO_00888	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPHNICFO_00889	1.48e-178	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NPHNICFO_00890	1.05e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPHNICFO_00891	4.65e-296	ymfH	-	-	S	-	-	-	Peptidase M16
NPHNICFO_00892	2.47e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NPHNICFO_00893	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPHNICFO_00894	6.82e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
NPHNICFO_00895	8e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPHNICFO_00896	8.89e-269	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
NPHNICFO_00897	1.2e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NPHNICFO_00898	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NPHNICFO_00899	6.98e-306	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NPHNICFO_00900	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NPHNICFO_00901	2.28e-219	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPHNICFO_00902	3.58e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPHNICFO_00903	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NPHNICFO_00904	2.51e-143	-	-	-	S	-	-	-	CYTH
NPHNICFO_00905	5.4e-140	yjbH	-	-	Q	-	-	-	Thioredoxin
NPHNICFO_00906	6e-212	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPHNICFO_00907	1.15e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPHNICFO_00908	6.58e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPHNICFO_00909	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPHNICFO_00910	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NPHNICFO_00911	1.02e-34	-	-	-	-	-	-	-	-
NPHNICFO_00912	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPHNICFO_00913	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NPHNICFO_00914	1.18e-193	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_00915	8.01e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_00916	7.1e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
NPHNICFO_00917	2.91e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
NPHNICFO_00918	1.94e-213	-	-	-	S	-	-	-	DNA/RNA non-specific endonuclease
NPHNICFO_00919	7.57e-271	-	-	-	M	-	-	-	domain protein
NPHNICFO_00921	4.37e-119	-	-	-	-	-	-	-	-
NPHNICFO_00922	7.09e-180	-	-	-	-	-	-	-	-
NPHNICFO_00923	8.64e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPHNICFO_00924	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPHNICFO_00925	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NPHNICFO_00926	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NPHNICFO_00927	2.91e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NPHNICFO_00928	2.36e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPHNICFO_00929	2.5e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPHNICFO_00930	1.09e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NPHNICFO_00931	7.69e-77	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NPHNICFO_00932	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NPHNICFO_00933	3.44e-200	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPHNICFO_00934	9.17e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPHNICFO_00935	4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPHNICFO_00936	2.71e-158	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NPHNICFO_00937	2.23e-202	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPHNICFO_00938	7.13e-139	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPHNICFO_00939	1.45e-183	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPHNICFO_00940	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NPHNICFO_00941	3.88e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPHNICFO_00942	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPHNICFO_00943	9.01e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NPHNICFO_00944	2.46e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPHNICFO_00945	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPHNICFO_00946	1.91e-85	-	-	-	-	-	-	-	-
NPHNICFO_00947	3e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NPHNICFO_00948	6.23e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPHNICFO_00949	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NPHNICFO_00950	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NPHNICFO_00951	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NPHNICFO_00952	3.61e-244	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NPHNICFO_00953	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPHNICFO_00954	8.88e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPHNICFO_00955	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPHNICFO_00956	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPHNICFO_00957	8.98e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_00958	1.45e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPHNICFO_00959	5.71e-201	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPHNICFO_00960	4.81e-94	-	-	-	L	-	-	-	nuclease
NPHNICFO_00961	5.57e-187	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NPHNICFO_00962	2e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
NPHNICFO_00963	3.21e-244	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPHNICFO_00964	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPHNICFO_00965	2.94e-42	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NPHNICFO_00966	2.48e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPHNICFO_00967	4.39e-133	-	-	-	I	-	-	-	PAP2 superfamily
NPHNICFO_00968	1.15e-236	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPHNICFO_00969	7.92e-81	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NPHNICFO_00970	1.72e-09	-	-	-	-	-	-	-	-
NPHNICFO_00971	2.58e-45	-	-	-	-	-	-	-	-
NPHNICFO_00972	1.12e-94	-	-	-	-	-	-	-	-
NPHNICFO_00973	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPHNICFO_00974	5.41e-87	-	-	-	-	-	-	-	-
NPHNICFO_00975	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
NPHNICFO_00976	4.2e-200	-	-	-	S	-	-	-	phage tail
NPHNICFO_00977	0.0	-	-	-	D	-	-	-	SLT domain
NPHNICFO_00980	2.02e-131	-	-	-	S	-	-	-	Phage tail tube protein
NPHNICFO_00982	4.24e-59	-	-	-	S	-	-	-	exonuclease activity
NPHNICFO_00984	4.73e-85	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NPHNICFO_00985	8.96e-223	-	-	-	-	-	-	-	-
NPHNICFO_00986	1.26e-120	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NPHNICFO_00987	9.28e-79	-	-	-	S	-	-	-	YjcQ protein
NPHNICFO_00988	8.72e-48	-	-	-	-	-	-	-	-
NPHNICFO_00989	0.0	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
NPHNICFO_00990	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NPHNICFO_00991	0.0	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
NPHNICFO_00992	6.2e-103	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NPHNICFO_00993	3.7e-155	-	-	-	-	-	-	-	-
NPHNICFO_00994	6.16e-121	-	-	-	S	-	-	-	Super-infection exclusion protein B
NPHNICFO_00996	3.11e-105	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
NPHNICFO_00998	3.14e-137	-	-	-	-	-	-	-	-
NPHNICFO_01002	5.8e-216	-	-	-	L	-	-	-	DnaD domain protein
NPHNICFO_01003	3.98e-185	-	-	-	S	-	-	-	ERF superfamily
NPHNICFO_01004	1.25e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
NPHNICFO_01005	1.14e-26	-	-	-	-	-	-	-	-
NPHNICFO_01006	1.04e-27	-	-	-	-	-	-	-	-
NPHNICFO_01007	2.67e-43	-	-	-	-	-	-	-	-
NPHNICFO_01009	3.87e-46	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NPHNICFO_01010	1.39e-116	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2321)
NPHNICFO_01011	5.43e-179	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
NPHNICFO_01012	3.8e-47	-	-	-	K	-	-	-	Protein of unknown function (DUF739)
NPHNICFO_01013	1e-96	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPHNICFO_01014	1.36e-100	-	-	-	E	-	-	-	Zn peptidase
NPHNICFO_01015	8.1e-118	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NPHNICFO_01016	1.74e-46	-	-	-	-	-	-	-	-
NPHNICFO_01017	1.12e-64	-	-	-	-	-	-	-	-
NPHNICFO_01019	8.72e-68	-	-	-	-	-	-	-	-
NPHNICFO_01020	1.19e-169	-	-	-	-	-	-	-	-
NPHNICFO_01021	8.79e-284	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPHNICFO_01023	1.52e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
NPHNICFO_01024	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NPHNICFO_01025	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NPHNICFO_01026	8.21e-127	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPHNICFO_01027	3.46e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPHNICFO_01028	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHNICFO_01029	0.0	potE	-	-	E	-	-	-	Amino Acid
NPHNICFO_01030	5.93e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPHNICFO_01031	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPHNICFO_01032	1.33e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NPHNICFO_01033	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPHNICFO_01034	1.73e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPHNICFO_01035	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NPHNICFO_01036	8.28e-112	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPHNICFO_01037	1.13e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPHNICFO_01038	8.9e-28	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NPHNICFO_01039	8.67e-85	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NPHNICFO_01040	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NPHNICFO_01041	1.5e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPHNICFO_01042	1.04e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPHNICFO_01043	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPHNICFO_01044	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPHNICFO_01045	1.32e-63	-	-	-	J	-	-	-	ribosomal protein
NPHNICFO_01046	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NPHNICFO_01047	2.72e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NPHNICFO_01048	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NPHNICFO_01049	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHNICFO_01050	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPHNICFO_01051	2.69e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NPHNICFO_01052	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NPHNICFO_01053	5.91e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPHNICFO_01054	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPHNICFO_01055	1.01e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NPHNICFO_01056	8.74e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPHNICFO_01057	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NPHNICFO_01058	1.13e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NPHNICFO_01059	1.16e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NPHNICFO_01060	5.39e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NPHNICFO_01061	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_01062	2.26e-13	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_01063	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_01064	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NPHNICFO_01065	5.94e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
NPHNICFO_01066	7.82e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPHNICFO_01067	2.15e-151	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NPHNICFO_01068	2.61e-96	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
NPHNICFO_01069	2.63e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPHNICFO_01070	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPHNICFO_01071	3.7e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPHNICFO_01072	2.07e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPHNICFO_01073	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NPHNICFO_01074	1.99e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPHNICFO_01075	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPHNICFO_01076	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPHNICFO_01077	1.78e-275	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPHNICFO_01078	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NPHNICFO_01079	1.29e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPHNICFO_01080	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_01081	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_01082	6.42e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPHNICFO_01083	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_01084	8.34e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPHNICFO_01085	1.72e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPHNICFO_01086	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPHNICFO_01087	1.1e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPHNICFO_01088	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPHNICFO_01089	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NPHNICFO_01090	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPHNICFO_01091	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NPHNICFO_01092	9.07e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NPHNICFO_01093	3.86e-156	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NPHNICFO_01094	3.89e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPHNICFO_01095	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPHNICFO_01096	1.29e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NPHNICFO_01097	6.32e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPHNICFO_01098	2.38e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPHNICFO_01099	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPHNICFO_01100	3.3e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPHNICFO_01101	3.6e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NPHNICFO_01102	3.49e-63	-	-	-	-	-	-	-	-
NPHNICFO_01103	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NPHNICFO_01104	5.29e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NPHNICFO_01105	5.32e-208	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPHNICFO_01106	2.74e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHNICFO_01107	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHNICFO_01108	6.38e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPHNICFO_01109	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPHNICFO_01110	7.32e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NPHNICFO_01111	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPHNICFO_01112	1.57e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPHNICFO_01113	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NPHNICFO_01114	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NPHNICFO_01115	4.29e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NPHNICFO_01116	2.81e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPHNICFO_01117	3.98e-271	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NPHNICFO_01118	1.17e-17	-	-	-	-	-	-	-	-
NPHNICFO_01119	1.87e-84	-	-	-	-	-	-	-	-
NPHNICFO_01120	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NPHNICFO_01121	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NPHNICFO_01122	1.24e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NPHNICFO_01123	1.44e-72	-	-	-	-	-	-	-	-
NPHNICFO_01124	6.43e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPHNICFO_01125	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NPHNICFO_01126	6.33e-226	-	-	-	I	-	-	-	Carboxylesterase family
NPHNICFO_01127	3e-75	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPHNICFO_01128	1.93e-81	-	-	-	K	-	-	-	AraC-like ligand binding domain
NPHNICFO_01129	2.8e-171	-	-	-	GK	-	-	-	ROK family
NPHNICFO_01130	2.08e-13	-	-	-	GK	-	-	-	ROK family
NPHNICFO_01131	1.67e-104	-	-	-	M	-	-	-	Sortase family
NPHNICFO_01134	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPHNICFO_01135	1.22e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NPHNICFO_01136	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NPHNICFO_01137	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPHNICFO_01138	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPHNICFO_01139	7.06e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NPHNICFO_01140	1.98e-190	-	-	-	M	-	-	-	Glycosyl transferase family 2
NPHNICFO_01141	8.04e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NPHNICFO_01142	4.86e-92	-	-	-	-	-	-	-	-
NPHNICFO_01143	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPHNICFO_01144	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NPHNICFO_01146	1.98e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPHNICFO_01147	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NPHNICFO_01148	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPHNICFO_01149	3.67e-294	sptS	-	-	T	-	-	-	Histidine kinase
NPHNICFO_01150	1.75e-150	dltr	-	-	K	-	-	-	response regulator
NPHNICFO_01151	2.97e-149	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
NPHNICFO_01152	6.43e-211	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NPHNICFO_01153	3.2e-91	-	-	-	O	-	-	-	OsmC-like protein
NPHNICFO_01154	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPHNICFO_01155	6.12e-232	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01156	8.55e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPHNICFO_01157	1.64e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NPHNICFO_01158	2.97e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NPHNICFO_01159	9.59e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NPHNICFO_01160	3.74e-115	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
NPHNICFO_01161	1.56e-276	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPHNICFO_01163	1.24e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPHNICFO_01164	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NPHNICFO_01165	2.91e-94	-	-	-	-	-	-	-	-
NPHNICFO_01166	8.16e-111	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NPHNICFO_01167	2.49e-56	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NPHNICFO_01168	0.0	-	-	-	S	-	-	-	TerB-C domain
NPHNICFO_01169	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
NPHNICFO_01170	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NPHNICFO_01171	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPHNICFO_01172	1.84e-186	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NPHNICFO_01173	7.51e-316	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NPHNICFO_01174	1.53e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
NPHNICFO_01176	8.69e-187	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPHNICFO_01177	7.58e-98	-	-	-	-	-	-	-	-
NPHNICFO_01178	2.18e-130	-	-	-	-	-	-	-	-
NPHNICFO_01179	9.43e-188	-	-	-	D	-	-	-	Ftsk spoiiie family protein
NPHNICFO_01180	1.46e-195	-	-	-	S	-	-	-	Replication initiation factor
NPHNICFO_01181	6.62e-87	-	-	-	-	-	-	-	-
NPHNICFO_01182	1.23e-23	-	-	-	-	-	-	-	-
NPHNICFO_01183	1.09e-293	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPHNICFO_01184	4.89e-122	-	-	-	K	-	-	-	acetyltransferase
NPHNICFO_01185	4.37e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NPHNICFO_01186	5.68e-174	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NPHNICFO_01187	1.84e-155	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NPHNICFO_01188	1.35e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPHNICFO_01189	5.38e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPHNICFO_01190	5.15e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
NPHNICFO_01191	7.68e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPHNICFO_01192	7.71e-188	-	-	-	-	-	-	-	-
NPHNICFO_01193	7.02e-183	-	-	-	-	-	-	-	-
NPHNICFO_01194	6.46e-49	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NPHNICFO_01195	2.06e-192	-	-	-	-	-	-	-	-
NPHNICFO_01197	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
NPHNICFO_01198	1.1e-49	-	-	-	-	-	-	-	-
NPHNICFO_01199	4.93e-82	-	-	-	-	-	-	-	-
NPHNICFO_01200	6.61e-15	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NPHNICFO_01201	2.65e-108	-	-	-	L	-	-	-	transposase activity
NPHNICFO_01202	5.06e-31	-	-	-	-	-	-	-	-
NPHNICFO_01203	7.35e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPHNICFO_01204	3.41e-172	-	-	-	-	-	-	-	-
NPHNICFO_01205	2.66e-222	-	-	-	-	-	-	-	-
NPHNICFO_01206	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NPHNICFO_01207	8.74e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NPHNICFO_01208	1.38e-230	-	-	-	S	-	-	-	DUF218 domain
NPHNICFO_01209	3.29e-193	yxeH	-	-	S	-	-	-	hydrolase
NPHNICFO_01210	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
NPHNICFO_01211	3.18e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPHNICFO_01212	1.23e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPHNICFO_01213	2.87e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPHNICFO_01214	6.39e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPHNICFO_01215	1.34e-232	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NPHNICFO_01216	5.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPHNICFO_01217	1.36e-270	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPHNICFO_01218	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPHNICFO_01219	1.14e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPHNICFO_01220	9.4e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
NPHNICFO_01221	3.32e-285	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPHNICFO_01222	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPHNICFO_01223	3.8e-274	-	-	-	M	-	-	-	Glycosyl transferases group 1
NPHNICFO_01224	1.7e-163	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
NPHNICFO_01225	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPHNICFO_01226	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPHNICFO_01227	5.41e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NPHNICFO_01228	3.31e-201	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
NPHNICFO_01229	6.69e-239	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NPHNICFO_01230	0.0	-	-	-	G	-	-	-	isomerase
NPHNICFO_01231	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
NPHNICFO_01232	1.57e-196	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NPHNICFO_01233	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPHNICFO_01234	8.2e-218	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPHNICFO_01235	2.9e-215	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NPHNICFO_01236	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
NPHNICFO_01237	5.07e-151	-	-	-	C	-	-	-	nitroreductase
NPHNICFO_01238	3.44e-58	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
NPHNICFO_01239	2.29e-221	-	-	-	C	-	-	-	Oxidoreductase
NPHNICFO_01240	6.56e-97	-	-	-	S	-	-	-	SnoaL-like domain
NPHNICFO_01241	1.69e-13	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
NPHNICFO_01242	1.17e-116	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
NPHNICFO_01243	6.48e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NPHNICFO_01245	1.21e-188	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NPHNICFO_01246	1.4e-229	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
NPHNICFO_01247	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NPHNICFO_01248	1.49e-312	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPHNICFO_01249	8.89e-269	-	-	-	P	-	-	-	Major Facilitator Superfamily
NPHNICFO_01250	1.43e-110	yfhC	-	-	C	-	-	-	nitroreductase
NPHNICFO_01251	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NPHNICFO_01252	1.38e-71	-	-	-	-	-	-	-	-
NPHNICFO_01253	8.69e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
NPHNICFO_01254	2.01e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
NPHNICFO_01255	1.34e-141	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01256	2.62e-100	-	-	-	-	-	-	-	-
NPHNICFO_01257	2.06e-103	-	-	-	-	-	-	-	-
NPHNICFO_01258	8.49e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01259	5.94e-111	-	-	-	FG	-	-	-	HIT domain
NPHNICFO_01260	3.2e-64	-	-	-	S	-	-	-	MazG-like family
NPHNICFO_01261	6.81e-83	-	-	-	-	-	-	-	-
NPHNICFO_01262	4.85e-161	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPHNICFO_01263	3.11e-57	-	-	-	-	-	-	-	-
NPHNICFO_01264	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHNICFO_01265	2.32e-182	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NPHNICFO_01266	2.83e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPHNICFO_01267	2.99e-119	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
NPHNICFO_01268	2.26e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NPHNICFO_01269	9.39e-182	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NPHNICFO_01270	4.96e-146	-	-	-	-	-	-	-	-
NPHNICFO_01271	5.01e-106	-	-	-	-	-	-	-	-
NPHNICFO_01272	4.7e-120	-	-	-	S	-	-	-	AAA domain
NPHNICFO_01273	1.06e-195	-	-	-	M	-	-	-	Phosphotransferase enzyme family
NPHNICFO_01274	4.33e-109	-	-	-	F	-	-	-	NUDIX domain
NPHNICFO_01275	3.31e-192	-	-	-	F	-	-	-	Phosphorylase superfamily
NPHNICFO_01276	6.17e-193	-	-	-	F	-	-	-	Phosphorylase superfamily
NPHNICFO_01277	8.85e-111	-	-	-	S	-	-	-	ASCH
NPHNICFO_01278	9.13e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPHNICFO_01279	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPHNICFO_01280	5.97e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
NPHNICFO_01281	5.51e-200	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
NPHNICFO_01282	3.61e-269	-	-	-	G	-	-	-	Transmembrane secretion effector
NPHNICFO_01283	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NPHNICFO_01284	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NPHNICFO_01285	8.15e-241	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPHNICFO_01286	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NPHNICFO_01287	2.03e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NPHNICFO_01288	4.95e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
NPHNICFO_01289	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPHNICFO_01290	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPHNICFO_01291	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NPHNICFO_01292	1.32e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NPHNICFO_01293	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NPHNICFO_01294	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NPHNICFO_01295	2.33e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPHNICFO_01296	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NPHNICFO_01297	5.29e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPHNICFO_01298	1.96e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NPHNICFO_01299	2.77e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPHNICFO_01300	2.29e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPHNICFO_01301	1.17e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPHNICFO_01302	6.42e-287	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NPHNICFO_01303	1.38e-224	degV1	-	-	S	-	-	-	DegV family
NPHNICFO_01304	1.53e-74	-	-	-	-	-	-	-	-
NPHNICFO_01305	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NPHNICFO_01306	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPHNICFO_01307	4.09e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPHNICFO_01308	1.14e-252	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPHNICFO_01309	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPHNICFO_01310	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NPHNICFO_01311	1.32e-84	-	-	-	-	-	-	-	-
NPHNICFO_01312	5.52e-209	-	-	-	S	-	-	-	EDD domain protein, DegV family
NPHNICFO_01313	2.05e-198	-	-	-	-	-	-	-	-
NPHNICFO_01314	1.47e-212	lysR	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_01315	9.84e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NPHNICFO_01316	8.02e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NPHNICFO_01317	9.62e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPHNICFO_01318	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NPHNICFO_01319	4.97e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NPHNICFO_01320	1.19e-230	-	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_01321	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHNICFO_01322	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHNICFO_01323	1.62e-149	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPHNICFO_01324	3.34e-151	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NPHNICFO_01325	4.4e-213	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NPHNICFO_01326	2.15e-203	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPHNICFO_01327	6.66e-299	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NPHNICFO_01328	5.86e-255	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NPHNICFO_01329	3.55e-147	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPHNICFO_01330	1.11e-45	-	-	-	-	-	-	-	-
NPHNICFO_01331	8.27e-222	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
NPHNICFO_01332	2.56e-309	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
NPHNICFO_01333	2.98e-23	lysR	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_01334	8.47e-202	-	-	-	C	-	-	-	Aldo keto reductase
NPHNICFO_01335	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NPHNICFO_01336	9.65e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NPHNICFO_01337	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NPHNICFO_01338	2.67e-102	-	-	-	S	-	-	-	Cupin domain
NPHNICFO_01339	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPHNICFO_01340	3.96e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NPHNICFO_01342	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
NPHNICFO_01343	7.49e-64	-	-	-	-	-	-	-	-
NPHNICFO_01344	3.82e-181	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NPHNICFO_01345	8.17e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPHNICFO_01346	0.000502	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NPHNICFO_01347	2.71e-180	-	-	-	H	-	-	-	Nodulation protein S (NodS)
NPHNICFO_01348	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPHNICFO_01349	2.51e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPHNICFO_01350	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NPHNICFO_01351	8.45e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NPHNICFO_01352	6.39e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPHNICFO_01353	6.53e-291	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NPHNICFO_01354	4.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NPHNICFO_01355	2.48e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPHNICFO_01356	2.86e-135	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NPHNICFO_01357	1.42e-134	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPHNICFO_01358	5.2e-131	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NPHNICFO_01359	1.85e-316	-	-	-	T	-	-	-	GHKL domain
NPHNICFO_01360	5.04e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NPHNICFO_01361	2.53e-152	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NPHNICFO_01362	7.88e-143	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
NPHNICFO_01363	2.1e-21	-	-	-	S	-	-	-	reductase
NPHNICFO_01364	9.15e-11	-	-	-	S	-	-	-	reductase
NPHNICFO_01365	3.2e-145	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NPHNICFO_01366	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NPHNICFO_01367	6.47e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
NPHNICFO_01368	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_01369	2.81e-175	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
NPHNICFO_01370	3.56e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
NPHNICFO_01371	7.13e-56	-	-	-	-	-	-	-	-
NPHNICFO_01372	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPHNICFO_01373	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_01374	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_01375	1.2e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NPHNICFO_01376	8.03e-151	-	-	-	-	-	-	-	-
NPHNICFO_01378	1.03e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
NPHNICFO_01379	2.46e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPHNICFO_01380	9.68e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
NPHNICFO_01381	8.8e-129	-	-	-	S	ko:K06872	-	ko00000	TPM domain
NPHNICFO_01382	5.01e-233	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NPHNICFO_01383	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPHNICFO_01384	3.86e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NPHNICFO_01385	1.13e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPHNICFO_01386	1.15e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPHNICFO_01387	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NPHNICFO_01388	1.91e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NPHNICFO_01389	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPHNICFO_01390	3.93e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHNICFO_01391	3.02e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NPHNICFO_01392	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NPHNICFO_01393	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPHNICFO_01394	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPHNICFO_01395	4.64e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NPHNICFO_01396	1.36e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPHNICFO_01397	7.34e-290	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPHNICFO_01398	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPHNICFO_01399	4.16e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_01400	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
NPHNICFO_01401	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHNICFO_01402	7.07e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NPHNICFO_01403	3.08e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPHNICFO_01404	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPHNICFO_01405	4.39e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPHNICFO_01406	1.6e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NPHNICFO_01407	1.17e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPHNICFO_01408	2.16e-167	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
NPHNICFO_01409	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NPHNICFO_01410	2.23e-69	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NPHNICFO_01411	1.45e-236	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
NPHNICFO_01412	1.87e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHNICFO_01415	2.24e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
NPHNICFO_01416	2.96e-45	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPHNICFO_01417	1.92e-198	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPHNICFO_01419	1.91e-144	-	-	-	K	-	-	-	transcriptional regulator
NPHNICFO_01420	2.26e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NPHNICFO_01421	1.08e-218	-	-	-	K	-	-	-	Helix-turn-helix
NPHNICFO_01422	4.58e-146	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPHNICFO_01423	6.9e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPHNICFO_01424	1.3e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NPHNICFO_01425	4.14e-282	-	-	-	S	-	-	-	Membrane
NPHNICFO_01426	1.77e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPHNICFO_01427	2.98e-189	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NPHNICFO_01428	2.34e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPHNICFO_01429	3.27e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NPHNICFO_01430	9.58e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01431	2.3e-231	-	-	-	C	-	-	-	nadph quinone reductase
NPHNICFO_01432	1.53e-102	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_01433	1.17e-110	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPHNICFO_01434	6.72e-10	-	-	-	G	-	-	-	gluconokinase activity
NPHNICFO_01435	1.52e-124	-	-	-	-	-	-	-	-
NPHNICFO_01436	1.85e-53	-	-	-	-	-	-	-	-
NPHNICFO_01437	8.59e-106	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NPHNICFO_01438	4.04e-103	-	-	-	-	-	-	-	-
NPHNICFO_01439	6.92e-186	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NPHNICFO_01440	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPHNICFO_01441	4.9e-202	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
NPHNICFO_01442	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPHNICFO_01443	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPHNICFO_01444	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
NPHNICFO_01445	8.05e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPHNICFO_01446	8.03e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NPHNICFO_01447	4.48e-185	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPHNICFO_01448	7.67e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01449	0.0	-	-	-	E	-	-	-	amino acid
NPHNICFO_01450	8.98e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NPHNICFO_01451	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPHNICFO_01452	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPHNICFO_01453	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPHNICFO_01454	3.4e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPHNICFO_01455	3.16e-160	-	-	-	S	-	-	-	(CBS) domain
NPHNICFO_01456	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPHNICFO_01457	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHNICFO_01458	3.29e-234	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPHNICFO_01459	1.75e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPHNICFO_01460	4.69e-282	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
NPHNICFO_01472	2.12e-81	-	-	-	-	-	-	-	-
NPHNICFO_01474	6.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPHNICFO_01475	1.68e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPHNICFO_01476	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
NPHNICFO_01477	3.32e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPHNICFO_01478	3.44e-200	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NPHNICFO_01479	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPHNICFO_01480	2.12e-229	-	-	-	-	-	-	-	-
NPHNICFO_01481	3.17e-165	-	-	-	S	-	-	-	SNARE associated Golgi protein
NPHNICFO_01482	4.85e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPHNICFO_01483	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
NPHNICFO_01484	4.59e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPHNICFO_01485	2.74e-214	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NPHNICFO_01486	1.36e-215	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
NPHNICFO_01487	4.59e-107	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01488	3.57e-120	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPHNICFO_01489	1.92e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
NPHNICFO_01490	4.76e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NPHNICFO_01491	1.61e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPHNICFO_01492	4.66e-314	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
NPHNICFO_01493	2.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPHNICFO_01494	3.57e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
NPHNICFO_01495	8.41e-260	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NPHNICFO_01496	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPHNICFO_01497	1.25e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NPHNICFO_01498	9.54e-204	dkgB	-	-	S	-	-	-	reductase
NPHNICFO_01499	3.02e-255	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NPHNICFO_01500	4.88e-236	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
NPHNICFO_01501	1.07e-201	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPHNICFO_01502	8.74e-146	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPHNICFO_01503	2.34e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NPHNICFO_01504	1.14e-314	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPHNICFO_01505	6.63e-127	-	-	-	S	-	-	-	PAS domain
NPHNICFO_01506	1.4e-187	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPHNICFO_01508	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_01509	2.42e-281	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NPHNICFO_01510	1.34e-175	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPHNICFO_01511	1.19e-297	-	-	-	E	ko:K03294	-	ko00000	amino acid
NPHNICFO_01512	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHNICFO_01513	4.03e-301	yhdP	-	-	S	-	-	-	Transporter associated domain
NPHNICFO_01514	2.24e-169	-	-	-	-	-	-	-	-
NPHNICFO_01515	2.5e-153	-	-	-	C	-	-	-	nitroreductase
NPHNICFO_01516	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NPHNICFO_01517	3.01e-180	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NPHNICFO_01518	1.29e-70	-	-	-	S	-	-	-	Enterocin A Immunity
NPHNICFO_01519	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NPHNICFO_01520	5.86e-226	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NPHNICFO_01521	1.62e-165	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPHNICFO_01522	1.41e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPHNICFO_01523	1.98e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NPHNICFO_01524	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NPHNICFO_01525	2.89e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NPHNICFO_01526	6.89e-181	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPHNICFO_01527	4.68e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPHNICFO_01528	1.44e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPHNICFO_01529	8.44e-217	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPHNICFO_01530	9.53e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPHNICFO_01531	1.13e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01532	3.39e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01533	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPHNICFO_01534	7.86e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
NPHNICFO_01535	1.22e-270	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NPHNICFO_01536	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
NPHNICFO_01538	6.77e-71	-	-	-	S	-	-	-	Enterocin A Immunity
NPHNICFO_01542	2.98e-287	-	-	-	S	-	-	-	CAAX protease self-immunity
NPHNICFO_01543	1.09e-61	-	-	-	S	-	-	-	Enterocin A Immunity
NPHNICFO_01545	4.72e-134	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
NPHNICFO_01546	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPHNICFO_01547	1.2e-236	-	-	-	S	-	-	-	AAA domain
NPHNICFO_01548	2.48e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHNICFO_01549	4.81e-16	-	-	-	-	-	-	-	-
NPHNICFO_01550	7.29e-55	-	-	-	-	-	-	-	-
NPHNICFO_01551	5.88e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NPHNICFO_01552	2.23e-71	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NPHNICFO_01553	3.17e-166	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NPHNICFO_01554	4.42e-142	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NPHNICFO_01555	1.85e-121	-	-	-	GM	-	-	-	NmrA-like family
NPHNICFO_01558	1.24e-16	-	-	-	S	-	-	-	ORF located using Blastx
NPHNICFO_01576	0.0	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHNICFO_01577	4.33e-194	-	-	-	S	-	-	-	hydrolase
NPHNICFO_01578	2.65e-215	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NPHNICFO_01579	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHNICFO_01580	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPHNICFO_01581	2.23e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHNICFO_01582	1.12e-264	camS	-	-	S	-	-	-	sex pheromone
NPHNICFO_01583	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPHNICFO_01584	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NPHNICFO_01585	2.07e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NPHNICFO_01586	2.91e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NPHNICFO_01588	6.69e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NPHNICFO_01589	4.17e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
NPHNICFO_01590	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHNICFO_01591	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHNICFO_01592	7.88e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPHNICFO_01593	5.33e-30	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NPHNICFO_01594	3.59e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPHNICFO_01595	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPHNICFO_01596	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NPHNICFO_01597	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPHNICFO_01598	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHNICFO_01599	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPHNICFO_01600	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPHNICFO_01601	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPHNICFO_01602	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPHNICFO_01603	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPHNICFO_01604	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPHNICFO_01605	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NPHNICFO_01607	2.37e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NPHNICFO_01608	2.31e-312	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NPHNICFO_01609	1.46e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPHNICFO_01610	1.96e-314	ynbB	-	-	P	-	-	-	aluminum resistance
NPHNICFO_01611	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NPHNICFO_01612	0.0	-	-	-	E	-	-	-	Amino acid permease
NPHNICFO_01613	8.13e-208	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPHNICFO_01614	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPHNICFO_01618	2.78e-32	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
NPHNICFO_01619	6.99e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
NPHNICFO_01620	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPHNICFO_01622	4.16e-168	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
NPHNICFO_01623	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHNICFO_01624	2.35e-107	-	-	-	-	-	-	-	-
NPHNICFO_01625	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPHNICFO_01626	1.83e-97	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPHNICFO_01627	1.2e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHNICFO_01628	1.24e-76	-	-	-	-	-	-	-	-
NPHNICFO_01629	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NPHNICFO_01630	5.5e-161	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHNICFO_01631	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NPHNICFO_01633	1.86e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPHNICFO_01634	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
NPHNICFO_01635	1.2e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPHNICFO_01636	1.59e-268	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPHNICFO_01637	1.67e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
NPHNICFO_01638	3.83e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPHNICFO_01639	6.21e-152	-	-	-	-	-	-	-	-
NPHNICFO_01640	7.72e-228	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NPHNICFO_01641	9.65e-95	-	-	-	S	-	-	-	GtrA-like protein
NPHNICFO_01642	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHNICFO_01643	6.15e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
NPHNICFO_01644	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHNICFO_01645	2.4e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NPHNICFO_01646	3.27e-191	-	-	-	-	-	-	-	-
NPHNICFO_01647	8.33e-182	-	-	-	-	-	-	-	-
NPHNICFO_01648	4.31e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NPHNICFO_01649	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NPHNICFO_01650	1.13e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NPHNICFO_01651	1.15e-88	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPHNICFO_01652	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NPHNICFO_01653	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPHNICFO_01654	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NPHNICFO_01655	3.41e-37	-	-	-	-	-	-	-	-
NPHNICFO_01656	1.44e-176	-	-	-	-	-	-	-	-
NPHNICFO_01657	4.33e-95	-	-	-	-	-	-	-	-
NPHNICFO_01658	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPHNICFO_01659	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPHNICFO_01660	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
NPHNICFO_01661	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NPHNICFO_01662	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPHNICFO_01663	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPHNICFO_01664	7.3e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NPHNICFO_01665	1.33e-174	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPHNICFO_01666	0.0	-	-	-	D	-	-	-	transport
NPHNICFO_01667	2.95e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
NPHNICFO_01668	7.1e-291	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPHNICFO_01669	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NPHNICFO_01670	6.48e-136	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPHNICFO_01671	1.51e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPHNICFO_01672	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NPHNICFO_01673	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NPHNICFO_01674	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPHNICFO_01675	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPHNICFO_01676	3.38e-109	-	-	-	-	-	-	-	-
NPHNICFO_01677	6.11e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPHNICFO_01678	1.11e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPHNICFO_01679	1.28e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPHNICFO_01680	1.16e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
NPHNICFO_01682	6.03e-114	usp5	-	-	T	-	-	-	universal stress protein
NPHNICFO_01683	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPHNICFO_01684	3.53e-169	-	-	-	K	-	-	-	UTRA domain
NPHNICFO_01685	1.76e-128	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPHNICFO_01686	1.56e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
NPHNICFO_01687	5.08e-282	-	-	-	S	-	-	-	zinc-ribbon domain
NPHNICFO_01688	2.66e-88	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NPHNICFO_01689	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NPHNICFO_01690	8.1e-191	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NPHNICFO_01691	9.66e-110	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPHNICFO_01692	5.34e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPHNICFO_01693	1.01e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
NPHNICFO_01694	2.69e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NPHNICFO_01695	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NPHNICFO_01696	6.18e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPHNICFO_01697	2.4e-157	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NPHNICFO_01698	8.68e-211	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NPHNICFO_01699	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPHNICFO_01700	2.79e-144	-	-	-	-	-	-	-	-
NPHNICFO_01701	3.19e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NPHNICFO_01702	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
NPHNICFO_01703	1.14e-161	-	-	-	-	-	-	-	-
NPHNICFO_01704	1.01e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPHNICFO_01705	4.11e-308	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPHNICFO_01706	1.5e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHNICFO_01707	2.78e-82	-	-	-	-	-	-	-	-
NPHNICFO_01708	3.44e-161	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NPHNICFO_01709	5.52e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
NPHNICFO_01710	2.02e-220	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NPHNICFO_01712	5.53e-180	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHNICFO_01713	5.21e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPHNICFO_01714	1.81e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
NPHNICFO_01715	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHNICFO_01716	1.09e-104	-	-	-	-	-	-	-	-
NPHNICFO_01717	5.68e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NPHNICFO_01718	1.27e-76	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
NPHNICFO_01719	1.61e-48	ogt	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
NPHNICFO_01720	2.07e-166	terC	-	-	P	-	-	-	Integral membrane protein TerC family
NPHNICFO_01721	4.1e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NPHNICFO_01722	3.73e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NPHNICFO_01723	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPHNICFO_01724	1.19e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01725	5.01e-61	-	-	-	-	-	-	-	-
NPHNICFO_01726	2.05e-227	-	-	-	L	-	-	-	HNH nucleases
NPHNICFO_01727	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NPHNICFO_01728	4.96e-270	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
NPHNICFO_01729	2.59e-312	-	-	-	M	-	-	-	Glycosyl transferase
NPHNICFO_01731	6.23e-151	-	-	-	-	-	-	-	-
NPHNICFO_01732	1.14e-23	-	-	-	-	-	-	-	-
NPHNICFO_01733	7.84e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NPHNICFO_01734	2.31e-238	ysdE	-	-	P	-	-	-	Citrate transporter
NPHNICFO_01735	2.67e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NPHNICFO_01736	1.03e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NPHNICFO_01737	6.25e-217	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPHNICFO_01738	5.59e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NPHNICFO_01739	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01740	6.57e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NPHNICFO_01741	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPHNICFO_01742	1.17e-236	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NPHNICFO_01743	1.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NPHNICFO_01744	1.62e-190	yycI	-	-	S	-	-	-	YycH protein
NPHNICFO_01745	0.0	yycH	-	-	S	-	-	-	YycH protein
NPHNICFO_01746	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPHNICFO_01747	2.13e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPHNICFO_01749	0.0	-	-	-	S	-	-	-	domain, Protein
NPHNICFO_01750	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHNICFO_01751	8.92e-136	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPHNICFO_01752	9.69e-273	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHNICFO_01753	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NPHNICFO_01754	9.61e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
NPHNICFO_01755	4.32e-37	-	-	-	-	-	-	-	-
NPHNICFO_01756	9.4e-57	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPHNICFO_01757	2.96e-116	-	-	-	S	-	-	-	Alpha beta hydrolase
NPHNICFO_01758	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NPHNICFO_01759	3.21e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPHNICFO_01760	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
NPHNICFO_01761	1.5e-20	-	-	-	S	-	-	-	CsbD-like
NPHNICFO_01762	9.94e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPHNICFO_01763	6.07e-252	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
NPHNICFO_01764	2.37e-275	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
NPHNICFO_01765	7.46e-199	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
NPHNICFO_01766	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPHNICFO_01767	9.36e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPHNICFO_01768	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NPHNICFO_01769	1.62e-188	-	-	-	K	-	-	-	Helix-turn-helix domain
NPHNICFO_01770	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
NPHNICFO_01771	1.07e-23	-	-	-	-	-	-	-	-
NPHNICFO_01772	3.05e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
NPHNICFO_01773	4.52e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPHNICFO_01774	8.09e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NPHNICFO_01775	7.91e-244	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPHNICFO_01776	7.74e-257	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
NPHNICFO_01777	8.33e-185	-	-	-	K	-	-	-	Helix-turn-helix domain
NPHNICFO_01778	7.46e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NPHNICFO_01779	4.23e-213	-	-	-	I	-	-	-	Acyltransferase
NPHNICFO_01780	1.41e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
NPHNICFO_01782	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NPHNICFO_01784	0.0	-	-	-	-	-	-	-	-
NPHNICFO_01785	2.93e-281	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
NPHNICFO_01786	3.12e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NPHNICFO_01787	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NPHNICFO_01788	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPHNICFO_01789	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NPHNICFO_01790	1.42e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPHNICFO_01791	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPHNICFO_01792	2.06e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPHNICFO_01793	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NPHNICFO_01794	2.33e-39	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NPHNICFO_01795	1.24e-99	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
NPHNICFO_01796	1.26e-289	-	-	-	M	-	-	-	Pfam:DUF1792
NPHNICFO_01797	0.0	-	-	-	M	-	-	-	family 8
NPHNICFO_01798	0.0	-	-	-	M	-	-	-	family 8
NPHNICFO_01799	2.64e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPHNICFO_01800	1.8e-184	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NPHNICFO_01801	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01802	2.56e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NPHNICFO_01803	5.33e-209	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
NPHNICFO_01804	1.56e-311	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPHNICFO_01805	2.31e-166	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01806	1.28e-155	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NPHNICFO_01807	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHNICFO_01808	8.84e-141	-	-	-	-	-	-	-	-
NPHNICFO_01809	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
NPHNICFO_01810	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
NPHNICFO_01811	1.6e-29	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NPHNICFO_01812	3.85e-72	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NPHNICFO_01813	5.03e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NPHNICFO_01814	1.84e-53	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NPHNICFO_01817	2.12e-253	flp	-	-	V	-	-	-	Beta-lactamase
NPHNICFO_01818	1.71e-195	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
NPHNICFO_01819	1.3e-201	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NPHNICFO_01820	2.47e-125	-	-	-	-	-	-	-	-
NPHNICFO_01821	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
NPHNICFO_01822	6.6e-91	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPHNICFO_01823	1.7e-101	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPHNICFO_01824	1.82e-310	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NPHNICFO_01825	2.79e-59	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPHNICFO_01826	0.0	-	-	-	S	-	-	-	M26 IgA1-specific Metallo-endopeptidase C-terminal region
NPHNICFO_01828	3.74e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPHNICFO_01829	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPHNICFO_01830	1.57e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NPHNICFO_01831	7.67e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NPHNICFO_01832	0.0	yhaN	-	-	L	-	-	-	AAA domain
NPHNICFO_01833	2.15e-237	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHNICFO_01834	3.04e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPHNICFO_01835	2.53e-49	-	-	-	S	-	-	-	YtxH-like protein
NPHNICFO_01836	2.56e-85	-	-	-	-	-	-	-	-
NPHNICFO_01837	5.83e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NPHNICFO_01838	1.38e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPHNICFO_01839	1.04e-288	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPHNICFO_01840	1.77e-162	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPHNICFO_01841	5.91e-85	-	-	-	-	-	-	-	-
NPHNICFO_01842	4.72e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NPHNICFO_01843	3.58e-156	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHNICFO_01844	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NPHNICFO_01845	3.39e-165	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
NPHNICFO_01846	5.24e-169	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPHNICFO_01847	4.46e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPHNICFO_01848	1.19e-154	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NPHNICFO_01849	4.64e-294	degS	2.7.13.3	-	F	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
NPHNICFO_01850	9.32e-225	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
NPHNICFO_01851	8.55e-99	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NPHNICFO_01852	9.23e-124	levB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPHNICFO_01853	4.1e-190	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NPHNICFO_01854	4.16e-195	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
NPHNICFO_01855	6.34e-66	-	-	-	-	-	-	-	-
NPHNICFO_01856	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPHNICFO_01857	8.18e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPHNICFO_01858	3.74e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPHNICFO_01859	8.41e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPHNICFO_01860	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
NPHNICFO_01861	6.46e-210	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NPHNICFO_01862	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPHNICFO_01863	5.61e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPHNICFO_01864	1.43e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NPHNICFO_01865	3.73e-303	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPHNICFO_01866	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPHNICFO_01867	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NPHNICFO_01868	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPHNICFO_01869	6.48e-243	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPHNICFO_01870	5.48e-114	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NPHNICFO_01871	1.37e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NPHNICFO_01872	2e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPHNICFO_01873	8.88e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NPHNICFO_01874	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPHNICFO_01875	4.15e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NPHNICFO_01876	3.13e-122	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NPHNICFO_01877	1.89e-169	csrR	-	-	K	-	-	-	response regulator
NPHNICFO_01878	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPHNICFO_01879	9.51e-217	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHNICFO_01880	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NPHNICFO_01881	3.14e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHNICFO_01882	2.05e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPHNICFO_01883	9.43e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPHNICFO_01884	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHNICFO_01885	6.41e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPHNICFO_01886	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHNICFO_01887	0.0	-	-	-	S	-	-	-	membrane
NPHNICFO_01888	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPHNICFO_01889	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPHNICFO_01890	1.67e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPHNICFO_01891	2.67e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
NPHNICFO_01892	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NPHNICFO_01893	2.09e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NPHNICFO_01894	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NPHNICFO_01895	1.32e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPHNICFO_01896	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NPHNICFO_01897	6.96e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPHNICFO_01898	9.84e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPHNICFO_01900	8.06e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPHNICFO_01901	6.12e-278	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NPHNICFO_01902	4.19e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NPHNICFO_01903	1.98e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NPHNICFO_01904	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHNICFO_01905	5.43e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NPHNICFO_01906	1.37e-146	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NPHNICFO_01907	2.36e-116	-	-	-	-	-	-	-	-
NPHNICFO_01908	2.41e-101	-	-	-	-	-	-	-	-
NPHNICFO_01909	5.48e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NPHNICFO_01910	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP