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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MADBFOCO_00001	9.95e-58	-	-	-	-	-	-	-	-
MADBFOCO_00002	3.84e-49	-	-	-	-	-	-	-	-
MADBFOCO_00003	2.83e-121	-	-	-	-	-	-	-	-
MADBFOCO_00004	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MADBFOCO_00005	1.08e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MADBFOCO_00006	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MADBFOCO_00007	5.46e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MADBFOCO_00008	1.85e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MADBFOCO_00009	6.45e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MADBFOCO_00010	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MADBFOCO_00011	9.43e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MADBFOCO_00012	1.79e-155	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MADBFOCO_00013	1.26e-38	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
MADBFOCO_00014	2.84e-13	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
MADBFOCO_00015	3.34e-218	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MADBFOCO_00016	2.46e-83	-	-	-	L	ko:K19090	-	ko00000,ko02048	CRISPR-associated protein Cas5
MADBFOCO_00017	1.12e-131	-	-	-	L	ko:K19075	-	ko00000,ko02048	CRISPR-associated negative auto-regulator DevR/Csa2
MADBFOCO_00018	1.67e-127	-	-	-	S	ko:K19088	-	ko00000,ko02048	CRISPR-associated protein (Cas_CXXC_CXXC)
MADBFOCO_00019	1.08e-52	-	-	-	L	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR associated protein Cas6
MADBFOCO_00020	6.01e-182	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MADBFOCO_00021	3.53e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MADBFOCO_00022	7.71e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MADBFOCO_00023	5.2e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MADBFOCO_00024	8.53e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MADBFOCO_00025	3.01e-122	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MADBFOCO_00026	1.44e-138	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MADBFOCO_00027	4e-109	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MADBFOCO_00028	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MADBFOCO_00029	2.41e-45	-	-	-	-	-	-	-	-
MADBFOCO_00030	7.09e-119	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MADBFOCO_00031	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MADBFOCO_00032	2.1e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MADBFOCO_00033	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MADBFOCO_00034	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MADBFOCO_00035	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MADBFOCO_00036	7.71e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MADBFOCO_00037	5.04e-71	-	-	-	-	-	-	-	-
MADBFOCO_00038	1.74e-68	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00039	2.84e-24	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00040	2.42e-156	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00041	1.13e-204	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00042	2.57e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MADBFOCO_00043	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MADBFOCO_00044	4.18e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MADBFOCO_00045	8.06e-115	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MADBFOCO_00047	6.87e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MADBFOCO_00048	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MADBFOCO_00049	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MADBFOCO_00050	7.94e-271	camS	-	-	S	-	-	-	sex pheromone
MADBFOCO_00051	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MADBFOCO_00052	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MADBFOCO_00053	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MADBFOCO_00054	1.08e-216	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MADBFOCO_00055	1.12e-146	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MADBFOCO_00056	7.31e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MADBFOCO_00057	9.6e-73	-	-	-	-	-	-	-	-
MADBFOCO_00058	4.67e-313	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MADBFOCO_00059	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MADBFOCO_00060	6.7e-315	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MADBFOCO_00061	1.9e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MADBFOCO_00062	4.7e-99	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MADBFOCO_00063	7.23e-313	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MADBFOCO_00064	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MADBFOCO_00065	2.03e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MADBFOCO_00066	6.02e-151	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MADBFOCO_00067	1.79e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MADBFOCO_00068	2.16e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MADBFOCO_00069	9.04e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MADBFOCO_00070	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MADBFOCO_00071	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MADBFOCO_00072	8.03e-277	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MADBFOCO_00073	1.81e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MADBFOCO_00074	5.14e-58	-	-	-	M	-	-	-	Lysin motif
MADBFOCO_00075	1.08e-100	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MADBFOCO_00076	4.13e-28	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MADBFOCO_00077	1.1e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MADBFOCO_00078	8.17e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MADBFOCO_00079	4.26e-168	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MADBFOCO_00080	1.62e-80	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MADBFOCO_00081	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MADBFOCO_00082	1.08e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MADBFOCO_00084	1.32e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
MADBFOCO_00085	4.63e-235	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
MADBFOCO_00086	2.86e-140	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MADBFOCO_00087	3.05e-160	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MADBFOCO_00088	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MADBFOCO_00089	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MADBFOCO_00090	3.91e-135	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MADBFOCO_00091	3.44e-134	-	-	-	-	-	-	-	-
MADBFOCO_00092	1.03e-214	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00095	4.46e-46	-	-	-	-	-	-	-	-
MADBFOCO_00097	4.65e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MADBFOCO_00098	7.19e-94	-	-	-	L	-	-	-	IS1381, transposase OrfA
MADBFOCO_00099	1.09e-119	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MADBFOCO_00100	2.33e-156	-	-	-	-	-	-	-	-
MADBFOCO_00101	1.06e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MADBFOCO_00102	2.5e-183	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MADBFOCO_00103	4.23e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
MADBFOCO_00104	8.42e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_00105	1.94e-229	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_00106	3.4e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00107	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00108	4.74e-51	-	-	-	-	-	-	-	-
MADBFOCO_00109	1.52e-144	-	-	-	K	-	-	-	WHG domain
MADBFOCO_00110	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00111	9.79e-144	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00112	5.95e-36	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00113	4.73e-73	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00114	2.14e-220	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MADBFOCO_00115	2e-277	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MADBFOCO_00116	7.76e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MADBFOCO_00117	9.81e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MADBFOCO_00118	1.34e-151	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MADBFOCO_00120	3.65e-26	-	-	-	K	-	-	-	rpiR family
MADBFOCO_00121	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MADBFOCO_00122	3.29e-76	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_00123	1.2e-193	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MADBFOCO_00124	7.53e-203	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MADBFOCO_00125	1.3e-171	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MADBFOCO_00126	3.54e-126	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
MADBFOCO_00127	9.02e-42	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MADBFOCO_00128	5.89e-91	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MADBFOCO_00129	1.63e-201	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MADBFOCO_00130	3.06e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MADBFOCO_00131	4.88e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MADBFOCO_00132	2.96e-145	-	-	-	S	-	-	-	CYTH
MADBFOCO_00133	3.88e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
MADBFOCO_00134	1.86e-204	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MADBFOCO_00135	4.31e-177	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MADBFOCO_00136	1.54e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MADBFOCO_00137	3.66e-89	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MADBFOCO_00138	7.1e-150	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MADBFOCO_00139	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MADBFOCO_00140	9.47e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MADBFOCO_00143	4.58e-96	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MADBFOCO_00144	7.93e-124	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MADBFOCO_00145	1.95e-94	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00146	9.17e-53	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00147	4.09e-58	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00148	1.84e-94	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00149	4.92e-82	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_00150	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_00151	1.34e-278	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MADBFOCO_00154	2.73e-152	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_00155	5.04e-173	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MADBFOCO_00156	1.2e-75	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MADBFOCO_00157	6.44e-58	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MADBFOCO_00158	1.63e-257	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
MADBFOCO_00159	9.07e-156	-	-	-	S	-	-	-	cellulase activity
MADBFOCO_00160	2.78e-97	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MADBFOCO_00161	1.96e-97	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
MADBFOCO_00162	5.21e-255	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MADBFOCO_00163	7.94e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MADBFOCO_00164	3.97e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MADBFOCO_00165	1.83e-112	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MADBFOCO_00166	9.84e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MADBFOCO_00167	8.11e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MADBFOCO_00168	1.99e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MADBFOCO_00169	4.16e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MADBFOCO_00170	1.52e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MADBFOCO_00171	8.42e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MADBFOCO_00172	9.54e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MADBFOCO_00173	2.64e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MADBFOCO_00174	6.03e-57	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MADBFOCO_00175	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MADBFOCO_00176	1.53e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MADBFOCO_00177	6.69e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MADBFOCO_00178	3.75e-112	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MADBFOCO_00179	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MADBFOCO_00180	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MADBFOCO_00181	1.6e-97	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MADBFOCO_00182	2.72e-91	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MADBFOCO_00183	1.88e-34	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MADBFOCO_00184	1.43e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MADBFOCO_00185	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MADBFOCO_00186	1.5e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MADBFOCO_00187	9.02e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MADBFOCO_00188	4.93e-221	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MADBFOCO_00189	6.67e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MADBFOCO_00190	6.23e-19	-	-	-	-	-	-	-	-
MADBFOCO_00191	6.9e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MADBFOCO_00192	4.28e-226	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MADBFOCO_00193	6.62e-128	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MADBFOCO_00194	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00195	1.22e-221	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MADBFOCO_00196	1.77e-74	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MADBFOCO_00197	1.25e-10	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MADBFOCO_00198	5.46e-25	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MADBFOCO_00199	1.99e-83	-	-	-	L	-	-	-	Helix-turn-helix domain
MADBFOCO_00200	3.86e-206	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MADBFOCO_00201	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MADBFOCO_00202	7.25e-243	ysdE	-	-	P	-	-	-	Citrate transporter
MADBFOCO_00203	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MADBFOCO_00204	2.98e-24	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MADBFOCO_00205	9.69e-25	-	-	-	-	-	-	-	-
MADBFOCO_00206	4.3e-195	-	-	-	-	-	-	-	-
MADBFOCO_00207	1.98e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MADBFOCO_00208	4.82e-276	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MADBFOCO_00209	1.55e-89	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MADBFOCO_00211	2.65e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MADBFOCO_00212	1.25e-240	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MADBFOCO_00213	4.08e-62	-	-	-	S	ko:K09707	-	ko00000	ACT domain
MADBFOCO_00214	1.85e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MADBFOCO_00215	1.84e-35	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MADBFOCO_00216	4.74e-299	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MADBFOCO_00217	1.44e-74	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MADBFOCO_00218	4.77e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MADBFOCO_00219	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MADBFOCO_00220	1.51e-121	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MADBFOCO_00221	1.22e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MADBFOCO_00222	4.02e-159	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MADBFOCO_00223	9.6e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MADBFOCO_00224	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MADBFOCO_00225	1.89e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MADBFOCO_00226	5.19e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MADBFOCO_00227	2.12e-164	csrR	-	-	K	-	-	-	response regulator
MADBFOCO_00228	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MADBFOCO_00229	1.67e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MADBFOCO_00230	3e-205	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MADBFOCO_00231	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MADBFOCO_00232	6.34e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MADBFOCO_00233	3.53e-64	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MADBFOCO_00234	5.46e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MADBFOCO_00235	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MADBFOCO_00236	2.74e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MADBFOCO_00237	9.25e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MADBFOCO_00238	1.21e-75	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MADBFOCO_00239	5.83e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_00240	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MADBFOCO_00241	1.57e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MADBFOCO_00243	1.7e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MADBFOCO_00244	1.12e-101	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MADBFOCO_00245	5.96e-112	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MADBFOCO_00246	5.07e-63	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MADBFOCO_00247	1.4e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MADBFOCO_00248	2.22e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MADBFOCO_00249	7.48e-10	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MADBFOCO_00250	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MADBFOCO_00251	1.56e-145	-	-	-	S	-	-	-	repeat protein
MADBFOCO_00252	5.5e-162	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MADBFOCO_00253	1.14e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MADBFOCO_00254	2.01e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MADBFOCO_00255	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MADBFOCO_00256	4.14e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MADBFOCO_00257	3.14e-57	-	-	-	-	-	-	-	-
MADBFOCO_00258	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MADBFOCO_00259	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MADBFOCO_00260	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MADBFOCO_00261	7.13e-165	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MADBFOCO_00262	1.4e-192	ylmH	-	-	S	-	-	-	S4 domain protein
MADBFOCO_00263	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MADBFOCO_00264	2.88e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MADBFOCO_00265	6.3e-267	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MADBFOCO_00266	2.81e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MADBFOCO_00268	2.99e-141	-	-	-	S	-	-	-	Plasmid replication protein
MADBFOCO_00269	4.62e-251	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MADBFOCO_00270	5.24e-145	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MADBFOCO_00271	1.26e-91	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MADBFOCO_00273	1.73e-81	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_00274	7.72e-41	-	-	-	E	-	-	-	Zn peptidase
MADBFOCO_00275	1.81e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MADBFOCO_00276	2.77e-137	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MADBFOCO_00277	8.93e-249	-	-	-	O	-	-	-	Heat shock 70 kDa protein
MADBFOCO_00278	1.42e-57	-	-	-	-	-	-	-	-
MADBFOCO_00279	6.49e-65	-	-	-	-	-	-	-	-
MADBFOCO_00280	1.54e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MADBFOCO_00281	1.4e-160	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00282	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
MADBFOCO_00283	2.66e-57	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_00284	4.13e-110	-	-	-	-	-	-	-	-
MADBFOCO_00285	7.53e-50	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MADBFOCO_00286	1.74e-52	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MADBFOCO_00287	2.91e-49	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MADBFOCO_00288	4.39e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MADBFOCO_00289	2.69e-116	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MADBFOCO_00290	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00291	6.58e-275	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MADBFOCO_00292	3.59e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MADBFOCO_00293	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MADBFOCO_00294	1.18e-14	-	-	-	-	-	-	-	-
MADBFOCO_00295	1.51e-161	-	-	-	-	-	-	-	-
MADBFOCO_00296	7.51e-166	-	-	-	F	-	-	-	glutamine amidotransferase
MADBFOCO_00297	9.06e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00298	1.07e-105	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MADBFOCO_00299	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00300	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MADBFOCO_00301	6.25e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MADBFOCO_00302	1.17e-247	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MADBFOCO_00303	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MADBFOCO_00304	1.01e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MADBFOCO_00305	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MADBFOCO_00306	1.34e-260	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MADBFOCO_00309	1.57e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MADBFOCO_00310	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MADBFOCO_00311	1.75e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MADBFOCO_00312	7.09e-76	-	-	-	-	-	-	-	-
MADBFOCO_00313	1.18e-113	-	-	-	-	-	-	-	-
MADBFOCO_00314	4.7e-92	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MADBFOCO_00315	1.27e-87	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MADBFOCO_00316	7.41e-226	-	-	-	S	-	-	-	DUF218 domain
MADBFOCO_00317	4.03e-104	-	-	-	-	-	-	-	-
MADBFOCO_00318	1.44e-141	-	-	-	-	-	-	-	-
MADBFOCO_00319	4.79e-177	-	-	-	EG	-	-	-	EamA-like transporter family
MADBFOCO_00320	5.64e-59	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
MADBFOCO_00322	8.64e-56	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MADBFOCO_00323	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MADBFOCO_00324	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MADBFOCO_00325	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MADBFOCO_00326	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MADBFOCO_00329	4.36e-104	-	-	-	-	-	-	-	-
MADBFOCO_00331	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MADBFOCO_00332	5.82e-250	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MADBFOCO_00333	1.53e-211	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MADBFOCO_00334	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MADBFOCO_00335	1.26e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MADBFOCO_00336	4.62e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MADBFOCO_00337	6.18e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MADBFOCO_00338	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
MADBFOCO_00339	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MADBFOCO_00340	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MADBFOCO_00341	1.7e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MADBFOCO_00342	8.34e-165	-	-	-	S	-	-	-	(CBS) domain
MADBFOCO_00343	3.96e-120	-	-	-	K	-	-	-	transcriptional regulator
MADBFOCO_00344	2.3e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MADBFOCO_00345	6.61e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MADBFOCO_00346	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MADBFOCO_00347	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MADBFOCO_00348	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MADBFOCO_00349	3.58e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MADBFOCO_00352	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MADBFOCO_00354	1.28e-37	-	-	-	-	-	-	-	-
MADBFOCO_00355	4.79e-59	-	-	-	V	-	-	-	ABC transporter transmembrane region
MADBFOCO_00356	8.4e-115	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MADBFOCO_00358	3.53e-123	-	-	-	-	-	-	-	-
MADBFOCO_00359	2.05e-60	-	-	-	-	-	-	-	-
MADBFOCO_00360	3.29e-52	-	-	-	-	-	-	-	-
MADBFOCO_00361	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
MADBFOCO_00362	3.62e-170	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MADBFOCO_00363	1.92e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MADBFOCO_00364	7.24e-22	-	-	-	-	-	-	-	-
MADBFOCO_00365	6.26e-25	-	-	-	-	-	-	-	-
MADBFOCO_00366	1.12e-119	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00367	1.67e-143	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MADBFOCO_00368	1.06e-161	-	-	-	-	-	-	-	-
MADBFOCO_00369	7e-304	-	-	-	S	-	-	-	response to antibiotic
MADBFOCO_00370	5e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00371	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MADBFOCO_00372	8.88e-208	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
MADBFOCO_00373	1.63e-109	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MADBFOCO_00374	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MADBFOCO_00375	5.02e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MADBFOCO_00376	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MADBFOCO_00377	8.97e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_00378	1.57e-141	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MADBFOCO_00379	1.06e-192	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_00380	4.94e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MADBFOCO_00381	5.84e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MADBFOCO_00382	1.17e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MADBFOCO_00383	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MADBFOCO_00384	3.19e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
MADBFOCO_00385	2.07e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MADBFOCO_00386	1.12e-190	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MADBFOCO_00387	2.26e-58	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MADBFOCO_00388	4.03e-82	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MADBFOCO_00389	2.41e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MADBFOCO_00390	4.2e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MADBFOCO_00391	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MADBFOCO_00392	3.29e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MADBFOCO_00393	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MADBFOCO_00394	5.89e-172	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MADBFOCO_00395	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MADBFOCO_00396	1.38e-59	-	-	-	-	-	-	-	-
MADBFOCO_00397	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00398	4.03e-137	-	-	-	K	-	-	-	LysR substrate binding domain
MADBFOCO_00399	2.75e-27	-	-	-	-	-	-	-	-
MADBFOCO_00400	1.29e-279	-	-	-	S	-	-	-	Sterol carrier protein domain
MADBFOCO_00401	2.7e-126	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MADBFOCO_00402	1.33e-66	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MADBFOCO_00403	2.68e-84	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MADBFOCO_00404	2e-140	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MADBFOCO_00405	4.02e-17	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MADBFOCO_00406	8.71e-54	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MADBFOCO_00407	2.77e-68	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MADBFOCO_00408	1.32e-33	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MADBFOCO_00409	2.83e-201	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MADBFOCO_00410	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MADBFOCO_00411	7.61e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MADBFOCO_00412	1.77e-92	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MADBFOCO_00413	5.87e-28	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MADBFOCO_00414	5.38e-110	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MADBFOCO_00415	2.62e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MADBFOCO_00416	3.35e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MADBFOCO_00417	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MADBFOCO_00418	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MADBFOCO_00419	4.27e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MADBFOCO_00420	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MADBFOCO_00421	1.29e-21	-	-	-	-	-	-	-	-
MADBFOCO_00422	3.72e-36	-	-	-	S	-	-	-	membrane
MADBFOCO_00423	1.11e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MADBFOCO_00424	4.32e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MADBFOCO_00425	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MADBFOCO_00426	1.78e-17	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MADBFOCO_00427	4.54e-55	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MADBFOCO_00428	1.18e-168	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MADBFOCO_00429	1.05e-45	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MADBFOCO_00430	6.05e-35	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MADBFOCO_00431	8.35e-91	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MADBFOCO_00432	1.43e-47	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MADBFOCO_00433	6.35e-300	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MADBFOCO_00434	1.84e-20	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MADBFOCO_00435	4.91e-241	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MADBFOCO_00436	5.16e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MADBFOCO_00437	7.39e-224	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MADBFOCO_00438	1.6e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MADBFOCO_00439	3.83e-83	-	-	-	K	-	-	-	Transcriptional regulator
MADBFOCO_00440	3.81e-82	-	-	-	K	-	-	-	Transcriptional regulator
MADBFOCO_00441	6.26e-14	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MADBFOCO_00442	4.8e-80	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MADBFOCO_00443	2.91e-311	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MADBFOCO_00444	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MADBFOCO_00445	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MADBFOCO_00446	7.04e-63	-	-	-	-	-	-	-	-
MADBFOCO_00447	3.81e-59	-	-	-	E	-	-	-	amino acid
MADBFOCO_00448	2.17e-64	-	-	-	-	-	-	-	-
MADBFOCO_00449	2.51e-115	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_00450	5.47e-46	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MADBFOCO_00451	5.51e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MADBFOCO_00452	5.67e-176	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MADBFOCO_00453	1.85e-48	-	-	-	-	-	-	-	-
MADBFOCO_00454	7.52e-95	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MADBFOCO_00455	1.37e-116	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MADBFOCO_00456	8.47e-129	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MADBFOCO_00457	1.85e-35	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MADBFOCO_00458	6.23e-47	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MADBFOCO_00459	8.68e-44	-	-	-	-	-	-	-	-
MADBFOCO_00460	5.7e-36	-	-	-	-	-	-	-	-
MADBFOCO_00463	1.55e-125	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MADBFOCO_00464	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MADBFOCO_00465	3.27e-286	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MADBFOCO_00466	7.36e-225	-	-	-	-	-	-	-	-
MADBFOCO_00467	4.12e-79	lysM	-	-	M	-	-	-	LysM domain
MADBFOCO_00468	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MADBFOCO_00469	3.15e-182	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MADBFOCO_00470	6.71e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MADBFOCO_00471	9.97e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MADBFOCO_00472	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MADBFOCO_00473	1.34e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MADBFOCO_00474	4.35e-125	-	-	-	-	-	-	-	-
MADBFOCO_00475	1.52e-205	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MADBFOCO_00476	2.33e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MADBFOCO_00477	1.56e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MADBFOCO_00478	1.87e-118	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MADBFOCO_00479	1.06e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MADBFOCO_00480	1.47e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MADBFOCO_00481	4.51e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MADBFOCO_00482	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00483	3.23e-180	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00484	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00485	8.69e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MADBFOCO_00486	5.29e-218	ybbR	-	-	S	-	-	-	YbbR-like protein
MADBFOCO_00487	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MADBFOCO_00488	1.76e-193	-	-	-	S	-	-	-	hydrolase
MADBFOCO_00489	7.18e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MADBFOCO_00490	1.31e-153	-	-	-	-	-	-	-	-
MADBFOCO_00491	2.06e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MADBFOCO_00492	5.85e-274	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MADBFOCO_00493	1.93e-83	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MADBFOCO_00494	2.58e-81	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MADBFOCO_00495	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MADBFOCO_00496	2.3e-207	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_00497	4.98e-49	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_00498	4.65e-75	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_00499	3.58e-237	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MADBFOCO_00500	1.32e-20	-	-	-	E	-	-	-	Amino acid permease
MADBFOCO_00501	1.28e-209	-	-	-	E	-	-	-	Amino acid permease
MADBFOCO_00502	1.34e-60	-	-	-	E	-	-	-	Amino acid permease
MADBFOCO_00503	3.44e-57	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MADBFOCO_00504	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MADBFOCO_00505	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MADBFOCO_00506	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MADBFOCO_00507	1.43e-151	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MADBFOCO_00508	1.21e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MADBFOCO_00509	7.81e-282	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MADBFOCO_00510	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MADBFOCO_00511	1.98e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00512	1.43e-58	-	-	-	M	-	-	-	domain, Protein
MADBFOCO_00513	4.32e-139	-	-	-	M	-	-	-	domain, Protein
MADBFOCO_00514	1.71e-81	-	3.2.1.4	GH5,GH9	M	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	domain protein
MADBFOCO_00515	5.92e-30	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
MADBFOCO_00516	3.69e-30	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MADBFOCO_00517	1.12e-122	-	-	-	-	-	-	-	-
MADBFOCO_00518	1.83e-33	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
MADBFOCO_00519	7.06e-114	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MADBFOCO_00520	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MADBFOCO_00521	1.14e-23	-	-	-	-	-	-	-	-
MADBFOCO_00522	5.36e-65	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_00523	4.91e-14	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_00524	1.04e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MADBFOCO_00525	2.26e-83	-	-	-	M	-	-	-	Rib/alpha-like repeat
MADBFOCO_00528	7.86e-27	-	-	-	-	-	-	-	-
MADBFOCO_00529	9.8e-38	-	-	-	-	-	-	-	-
MADBFOCO_00530	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MADBFOCO_00531	3.27e-71	-	-	-	-	-	-	-	-
MADBFOCO_00533	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MADBFOCO_00534	7.45e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MADBFOCO_00535	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MADBFOCO_00536	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MADBFOCO_00537	7.59e-268	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MADBFOCO_00538	1.56e-190	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MADBFOCO_00539	6.43e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MADBFOCO_00540	5.21e-254	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MADBFOCO_00541	1.32e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MADBFOCO_00542	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MADBFOCO_00543	8.64e-79	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MADBFOCO_00544	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MADBFOCO_00545	6.33e-148	-	-	-	-	-	-	-	-
MADBFOCO_00547	1.08e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MADBFOCO_00548	2.86e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MADBFOCO_00549	1.09e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MADBFOCO_00550	4.56e-138	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MADBFOCO_00551	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MADBFOCO_00552	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MADBFOCO_00553	6.67e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MADBFOCO_00554	3.64e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MADBFOCO_00555	9.15e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MADBFOCO_00556	2.02e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MADBFOCO_00557	4.49e-194	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MADBFOCO_00558	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MADBFOCO_00559	3.98e-116	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00560	6.86e-98	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00561	6.64e-45	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MADBFOCO_00562	2.06e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MADBFOCO_00563	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MADBFOCO_00564	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MADBFOCO_00565	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MADBFOCO_00566	2.55e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MADBFOCO_00567	2.87e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MADBFOCO_00568	4.3e-256	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MADBFOCO_00569	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MADBFOCO_00570	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MADBFOCO_00571	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MADBFOCO_00572	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MADBFOCO_00573	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MADBFOCO_00574	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MADBFOCO_00575	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MADBFOCO_00576	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MADBFOCO_00577	2.46e-271	-	-	-	-	-	-	-	-
MADBFOCO_00578	6.46e-27	-	-	-	-	-	-	-	-
MADBFOCO_00579	4.51e-263	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MADBFOCO_00580	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MADBFOCO_00581	1.81e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
MADBFOCO_00582	2.08e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
MADBFOCO_00583	4.97e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MADBFOCO_00584	1.68e-46	-	-	-	-	-	-	-	-
MADBFOCO_00585	1e-288	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MADBFOCO_00586	9.09e-280	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MADBFOCO_00587	3.07e-202	-	-	-	S	-	-	-	reductase
MADBFOCO_00588	2.13e-108	yxeH	-	-	S	-	-	-	hydrolase
MADBFOCO_00589	2.07e-58	yxeH	-	-	S	-	-	-	hydrolase
MADBFOCO_00590	9.09e-20	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MADBFOCO_00591	6.24e-98	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MADBFOCO_00592	4.95e-57	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MADBFOCO_00593	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MADBFOCO_00594	2.06e-93	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MADBFOCO_00595	2.42e-137	-	-	-	L	-	-	-	DDE superfamily endonuclease
MADBFOCO_00596	2.54e-130	-	-	-	V	-	-	-	ABC transporter transmembrane region
MADBFOCO_00597	6.25e-211	-	-	-	V	-	-	-	ABC transporter transmembrane region
MADBFOCO_00598	2.91e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MADBFOCO_00599	3.02e-32	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MADBFOCO_00600	3.42e-233	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MADBFOCO_00601	9.39e-167	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MADBFOCO_00602	1.09e-139	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MADBFOCO_00603	4.63e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MADBFOCO_00604	3.2e-241	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MADBFOCO_00605	2.68e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MADBFOCO_00606	5.24e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MADBFOCO_00607	1.25e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MADBFOCO_00608	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MADBFOCO_00609	6.93e-96	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MADBFOCO_00610	2.59e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MADBFOCO_00611	7.69e-294	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MADBFOCO_00612	6.55e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MADBFOCO_00613	8.57e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MADBFOCO_00614	6.25e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MADBFOCO_00615	3.15e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MADBFOCO_00616	1.24e-104	-	-	-	K	-	-	-	Transcriptional regulator
MADBFOCO_00617	5.77e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MADBFOCO_00618	3.86e-242	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MADBFOCO_00619	4.53e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MADBFOCO_00620	1.87e-133	-	-	-	L	-	-	-	Resolvase, N terminal domain
MADBFOCO_00621	1.47e-164	-	-	-	L	ko:K07485	-	ko00000	Transposase
MADBFOCO_00622	3.24e-80	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_00623	4.17e-204	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MADBFOCO_00624	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MADBFOCO_00625	9.8e-97	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MADBFOCO_00626	2.56e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MADBFOCO_00627	7.51e-23	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MADBFOCO_00628	5.17e-123	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
MADBFOCO_00629	7.19e-280	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MADBFOCO_00630	3.63e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MADBFOCO_00631	4.46e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MADBFOCO_00632	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MADBFOCO_00633	2.4e-125	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MADBFOCO_00634	4.28e-191	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MADBFOCO_00635	2.12e-228	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MADBFOCO_00636	3.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MADBFOCO_00637	4.33e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MADBFOCO_00638	2.64e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MADBFOCO_00639	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MADBFOCO_00640	3.89e-52	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
MADBFOCO_00641	4.33e-103	-	-	-	-	-	-	-	-
MADBFOCO_00655	7.3e-22	ps301	-	-	K	-	-	-	sequence-specific DNA binding
MADBFOCO_00656	3.32e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MADBFOCO_00657	5.75e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MADBFOCO_00659	3.22e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MADBFOCO_00660	1.08e-127	-	-	-	I	-	-	-	PAP2 superfamily
MADBFOCO_00661	6.69e-147	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MADBFOCO_00662	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MADBFOCO_00663	1.7e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MADBFOCO_00664	2.03e-111	yfhC	-	-	C	-	-	-	nitroreductase
MADBFOCO_00665	5.95e-14	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MADBFOCO_00666	4.37e-102	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MADBFOCO_00667	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_00668	1.7e-171	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MADBFOCO_00669	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MADBFOCO_00670	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MADBFOCO_00671	8.72e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MADBFOCO_00672	3.35e-55	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MADBFOCO_00673	1.26e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MADBFOCO_00674	4.56e-231	potE	-	-	E	-	-	-	Amino Acid
MADBFOCO_00675	2.75e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MADBFOCO_00676	1.71e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MADBFOCO_00677	1.01e-281	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MADBFOCO_00678	2.35e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MADBFOCO_00679	3.42e-194	-	-	-	-	-	-	-	-
MADBFOCO_00680	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MADBFOCO_00681	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MADBFOCO_00682	1.54e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MADBFOCO_00683	2.46e-224	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MADBFOCO_00684	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MADBFOCO_00685	3.56e-128	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MADBFOCO_00686	2.64e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MADBFOCO_00687	6.77e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MADBFOCO_00688	6.08e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MADBFOCO_00689	1.72e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MADBFOCO_00690	4.04e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MADBFOCO_00691	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MADBFOCO_00692	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MADBFOCO_00693	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MADBFOCO_00694	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MADBFOCO_00695	1.83e-37	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MADBFOCO_00696	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MADBFOCO_00697	4.36e-199	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MADBFOCO_00698	1.43e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MADBFOCO_00699	2.27e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MADBFOCO_00700	2.18e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MADBFOCO_00701	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MADBFOCO_00702	5.46e-193	-	-	-	-	-	-	-	-
MADBFOCO_00703	5.25e-122	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MADBFOCO_00704	2.5e-26	ynbB	-	-	P	-	-	-	aluminum resistance
MADBFOCO_00705	1.01e-79	ynbB	-	-	P	-	-	-	aluminum resistance
MADBFOCO_00706	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MADBFOCO_00707	9.81e-175	-	-	-	-	-	-	-	-
MADBFOCO_00708	7.86e-212	-	-	-	-	-	-	-	-
MADBFOCO_00709	5.73e-205	-	-	-	-	-	-	-	-
MADBFOCO_00710	1.02e-17	-	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00711	8.06e-149	-	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00712	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MADBFOCO_00713	4.52e-140	vanZ	-	-	V	-	-	-	VanZ like family
MADBFOCO_00714	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MADBFOCO_00715	1.35e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MADBFOCO_00716	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MADBFOCO_00717	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MADBFOCO_00718	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MADBFOCO_00719	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MADBFOCO_00720	8.83e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MADBFOCO_00721	5.3e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MADBFOCO_00722	6.55e-82	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MADBFOCO_00723	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MADBFOCO_00724	4.93e-164	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MADBFOCO_00725	7.93e-251	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_00726	1.85e-44	-	-	-	-	-	-	-	-
MADBFOCO_00727	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MADBFOCO_00728	2.26e-85	-	-	-	-	-	-	-	-
MADBFOCO_00729	2.21e-194	-	-	-	-	-	-	-	-
MADBFOCO_00730	7.05e-79	-	-	-	-	-	-	-	-
MADBFOCO_00731	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
MADBFOCO_00732	3.15e-103	-	-	-	-	-	-	-	-
MADBFOCO_00733	2.49e-86	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MADBFOCO_00734	5.29e-119	-	-	-	-	-	-	-	-
MADBFOCO_00735	4.12e-274	-	-	-	M	-	-	-	CHAP domain
MADBFOCO_00736	1.04e-284	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MADBFOCO_00737	0.0	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_00738	1.34e-153	-	-	-	-	-	-	-	-
MADBFOCO_00739	3.79e-71	-	-	-	-	-	-	-	-
MADBFOCO_00740	1.49e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
MADBFOCO_00741	5.44e-132	-	-	-	-	-	-	-	-
MADBFOCO_00742	6.82e-66	-	-	-	-	-	-	-	-
MADBFOCO_00743	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
MADBFOCO_00744	2.31e-35	-	-	-	-	-	-	-	-
MADBFOCO_00745	8.5e-55	-	-	-	-	-	-	-	-
MADBFOCO_00746	5.22e-161	-	-	-	S	-	-	-	Fic/DOC family
MADBFOCO_00747	2.21e-38	-	-	-	-	-	-	-	-
MADBFOCO_00748	1.7e-160	repA	-	-	S	-	-	-	Replication initiator protein A
MADBFOCO_00749	1.3e-158	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MADBFOCO_00750	8.5e-207	-	-	-	L	-	-	-	HNH nucleases
MADBFOCO_00751	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00752	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00753	2.32e-70	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MADBFOCO_00754	1.83e-35	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MADBFOCO_00755	1.67e-83	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MADBFOCO_00756	3.66e-161	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MADBFOCO_00757	5.51e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MADBFOCO_00758	1.19e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MADBFOCO_00759	4.64e-111	-	-	-	-	-	-	-	-
MADBFOCO_00760	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MADBFOCO_00761	1.97e-229	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MADBFOCO_00762	5.07e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MADBFOCO_00763	7.31e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MADBFOCO_00764	5.32e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MADBFOCO_00765	2.62e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MADBFOCO_00766	8.77e-151	-	-	-	GM	-	-	-	NmrA-like family
MADBFOCO_00767	1.17e-85	-	-	-	-	-	-	-	-
MADBFOCO_00768	4.33e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MADBFOCO_00769	2.69e-157	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_00770	4.16e-173	-	-	-	-	-	-	-	-
MADBFOCO_00771	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_00772	5.22e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00773	3.99e-297	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MADBFOCO_00774	3.08e-266	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MADBFOCO_00775	4.08e-114	-	-	-	-	-	-	-	-
MADBFOCO_00776	4.85e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MADBFOCO_00777	4.04e-169	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MADBFOCO_00778	2.64e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MADBFOCO_00779	1.07e-39	-	-	-	-	-	-	-	-
MADBFOCO_00780	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MADBFOCO_00781	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MADBFOCO_00782	8.23e-117	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MADBFOCO_00783	3.56e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MADBFOCO_00784	6.8e-115	usp5	-	-	T	-	-	-	universal stress protein
MADBFOCO_00785	1.6e-200	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MADBFOCO_00786	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MADBFOCO_00787	4.7e-170	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MADBFOCO_00788	7.76e-192	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MADBFOCO_00789	4.61e-142	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MADBFOCO_00790	1.05e-108	-	-	-	-	-	-	-	-
MADBFOCO_00791	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MADBFOCO_00792	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MADBFOCO_00793	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MADBFOCO_00796	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MADBFOCO_00797	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MADBFOCO_00798	1.94e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MADBFOCO_00799	7.38e-295	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MADBFOCO_00800	3.12e-291	yttB	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00801	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MADBFOCO_00802	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MADBFOCO_00803	2.62e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MADBFOCO_00804	1.19e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MADBFOCO_00805	7.79e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MADBFOCO_00806	3.41e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MADBFOCO_00807	4.97e-130	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MADBFOCO_00808	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_00809	2.42e-74	-	-	-	-	-	-	-	-
MADBFOCO_00810	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MADBFOCO_00811	3.69e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MADBFOCO_00812	4.99e-276	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MADBFOCO_00813	3.01e-136	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
MADBFOCO_00814	3.5e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MADBFOCO_00815	2.92e-273	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MADBFOCO_00816	1.65e-204	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MADBFOCO_00817	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00818	2.45e-62	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MADBFOCO_00819	1.81e-41	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MADBFOCO_00820	5.42e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MADBFOCO_00821	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MADBFOCO_00822	1.25e-114	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MADBFOCO_00823	2.02e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MADBFOCO_00824	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MADBFOCO_00825	4.16e-32	-	-	-	-	-	-	-	-
MADBFOCO_00826	5.91e-48	-	-	-	GK	-	-	-	ROK family
MADBFOCO_00827	5.45e-69	-	-	-	GK	-	-	-	ROK family
MADBFOCO_00828	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MADBFOCO_00829	5.03e-109	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00830	1.01e-52	-	-	-	-	-	-	-	-
MADBFOCO_00831	3.62e-24	-	-	-	C	-	-	-	nitroreductase
MADBFOCO_00832	2.92e-61	-	-	-	C	-	-	-	nitroreductase
MADBFOCO_00833	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MADBFOCO_00834	6.05e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MADBFOCO_00835	1.66e-197	-	-	-	E	ko:K03294	-	ko00000	amino acid
MADBFOCO_00836	1.3e-46	-	-	-	E	ko:K03294	-	ko00000	amino acid
MADBFOCO_00837	1.33e-165	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_00838	2.34e-268	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MADBFOCO_00839	1.63e-314	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MADBFOCO_00841	2.14e-35	-	-	-	-	-	-	-	-
MADBFOCO_00842	7.71e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MADBFOCO_00843	1.52e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
MADBFOCO_00844	5.69e-86	-	-	-	-	-	-	-	-
MADBFOCO_00845	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MADBFOCO_00846	1.57e-106	-	-	-	L	ko:K07496	-	ko00000	Transposase
MADBFOCO_00847	2.36e-86	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MADBFOCO_00848	1.2e-87	-	-	-	S	-	-	-	GtrA-like protein
MADBFOCO_00849	3.61e-102	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
MADBFOCO_00850	1.43e-94	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
MADBFOCO_00851	5.63e-311	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MADBFOCO_00852	3.47e-46	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
MADBFOCO_00853	7.23e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MADBFOCO_00854	5.59e-250	pbpX1	-	-	V	-	-	-	Beta-lactamase
MADBFOCO_00855	6.76e-45	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MADBFOCO_00856	4.01e-189	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00857	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_00858	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MADBFOCO_00859	2.67e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MADBFOCO_00860	2.26e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MADBFOCO_00861	9e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MADBFOCO_00862	2.69e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MADBFOCO_00863	1.84e-237	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MADBFOCO_00864	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MADBFOCO_00865	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MADBFOCO_00866	1.91e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MADBFOCO_00867	2.3e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MADBFOCO_00868	1.57e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MADBFOCO_00869	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MADBFOCO_00870	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MADBFOCO_00871	1.18e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MADBFOCO_00872	8.05e-248	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MADBFOCO_00873	2.64e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MADBFOCO_00874	1.32e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MADBFOCO_00875	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MADBFOCO_00876	1.37e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MADBFOCO_00877	1.42e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MADBFOCO_00878	1.83e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MADBFOCO_00879	2.99e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MADBFOCO_00880	1.89e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MADBFOCO_00881	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MADBFOCO_00882	9.28e-271	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MADBFOCO_00883	5.32e-35	-	-	-	S	-	-	-	Transglycosylase associated protein
MADBFOCO_00884	1.9e-15	-	-	-	S	-	-	-	CsbD-like
MADBFOCO_00885	3.64e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MADBFOCO_00886	8.33e-227	degV1	-	-	S	-	-	-	DegV family
MADBFOCO_00887	1.93e-54	-	-	-	G	-	-	-	Major Facilitator Superfamily
MADBFOCO_00888	3.23e-28	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
MADBFOCO_00889	2.9e-69	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00890	6.91e-117	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00892	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_00893	2.77e-30	-	-	-	-	-	-	-	-
MADBFOCO_00894	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
MADBFOCO_00896	9.05e-222	-	-	-	V	-	-	-	ABC transporter transmembrane region
MADBFOCO_00897	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MADBFOCO_00898	1.3e-44	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MADBFOCO_00899	6.93e-85	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
MADBFOCO_00900	1.18e-99	-	-	-	-	-	-	-	-
MADBFOCO_00901	1.04e-16	-	-	-	-	-	-	-	-
MADBFOCO_00902	3.35e-38	-	-	-	-	-	-	-	-
MADBFOCO_00903	1.1e-241	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00905	2.94e-50	-	-	-	-	-	-	-	-
MADBFOCO_00906	3.61e-267	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MADBFOCO_00907	9.56e-267	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MADBFOCO_00908	7.07e-103	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MADBFOCO_00909	1.79e-67	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MADBFOCO_00910	1.66e-162	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_00911	2.26e-28	-	-	-	-	-	-	-	-
MADBFOCO_00912	2.14e-107	-	-	-	-	-	-	-	-
MADBFOCO_00914	2.89e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
MADBFOCO_00915	0.0	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00916	4.29e-171	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_00917	5.05e-115	-	-	-	-	-	-	-	-
MADBFOCO_00918	6.36e-21	-	-	-	-	-	-	-	-
MADBFOCO_00919	1.08e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MADBFOCO_00920	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MADBFOCO_00921	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MADBFOCO_00922	6.59e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MADBFOCO_00923	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MADBFOCO_00924	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MADBFOCO_00925	3.3e-57	-	-	-	-	-	-	-	-
MADBFOCO_00930	9.07e-36	qacA	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00931	1.17e-30	qacA	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_00932	1.01e-209	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MADBFOCO_00935	5.23e-45	-	-	-	-	-	-	-	-
MADBFOCO_00937	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MADBFOCO_00938	3.43e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00939	2.87e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MADBFOCO_00940	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MADBFOCO_00941	4.9e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MADBFOCO_00942	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MADBFOCO_00943	1.36e-216	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MADBFOCO_00944	4.05e-90	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00945	8.54e-147	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_00946	2.97e-232	-	-	-	V	-	-	-	Restriction endonuclease
MADBFOCO_00947	3.17e-37	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00948	1.46e-95	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00949	1.22e-34	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_00950	2.8e-311	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MADBFOCO_00951	9.87e-193	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MADBFOCO_00952	1.09e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
MADBFOCO_00953	1.56e-114	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
MADBFOCO_00954	8.81e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MADBFOCO_00955	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
MADBFOCO_00956	3.61e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
MADBFOCO_00957	1.67e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MADBFOCO_00958	1.73e-24	-	-	-	-	-	-	-	-
MADBFOCO_00959	6.91e-55	-	-	-	-	-	-	-	-
MADBFOCO_00960	4.47e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00961	3.56e-161	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00962	6.32e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MADBFOCO_00963	1.34e-59	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MADBFOCO_00964	2.78e-95	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MADBFOCO_00966	1.19e-200	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
MADBFOCO_00967	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MADBFOCO_00968	1.01e-161	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
MADBFOCO_00969	4.09e-109	-	-	-	U	-	-	-	FFAT motif binding
MADBFOCO_00970	5.99e-55	-	-	-	U	-	-	-	FFAT motif binding
MADBFOCO_00971	3.12e-70	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
MADBFOCO_00972	3.22e-184	-	-	-	K	-	-	-	SIS domain
MADBFOCO_00973	6.28e-222	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00974	4.4e-268	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MADBFOCO_00975	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MADBFOCO_00976	7.93e-249	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MADBFOCO_00977	3.56e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MADBFOCO_00978	1.01e-24	-	-	-	-	-	-	-	-
MADBFOCO_00979	1.89e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MADBFOCO_00980	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00981	1.48e-122	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MADBFOCO_00982	9.47e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MADBFOCO_00983	3.82e-23	-	-	-	-	-	-	-	-
MADBFOCO_00984	7.12e-69	-	-	-	-	-	-	-	-
MADBFOCO_00985	8.03e-229	citR	-	-	K	-	-	-	Putative sugar-binding domain
MADBFOCO_00986	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
MADBFOCO_00987	4.22e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MADBFOCO_00988	8.74e-44	-	-	-	L	-	-	-	Transposase
MADBFOCO_00989	1.4e-189	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_00990	2.52e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MADBFOCO_00991	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00992	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_00993	5.69e-195	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_00994	2.39e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_00995	5.44e-170	ycaM	-	-	E	-	-	-	amino acid
MADBFOCO_00996	2.36e-72	ycaM	-	-	E	-	-	-	amino acid
MADBFOCO_00997	1.11e-196	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MADBFOCO_00998	0.0	-	-	-	S	-	-	-	SH3-like domain
MADBFOCO_00999	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MADBFOCO_01000	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MADBFOCO_01001	1.09e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MADBFOCO_01002	7.3e-212	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MADBFOCO_01006	3.89e-242	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
MADBFOCO_01008	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MADBFOCO_01009	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MADBFOCO_01010	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MADBFOCO_01011	1.4e-245	flp	-	-	V	-	-	-	Beta-lactamase
MADBFOCO_01012	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MADBFOCO_01013	6.28e-59	-	-	-	-	-	-	-	-
MADBFOCO_01014	2.21e-177	-	-	-	-	-	-	-	-
MADBFOCO_01015	9.61e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MADBFOCO_01016	7.5e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MADBFOCO_01017	7.65e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MADBFOCO_01018	1.53e-30	-	-	-	-	-	-	-	-
MADBFOCO_01019	1.35e-161	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
MADBFOCO_01020	8.76e-75	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MADBFOCO_01021	1.02e-258	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MADBFOCO_01022	1.87e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MADBFOCO_01023	7.12e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MADBFOCO_01024	2.7e-126	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
MADBFOCO_01025	5.36e-65	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
MADBFOCO_01026	2.03e-34	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
MADBFOCO_01027	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MADBFOCO_01028	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_01029	8.01e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_01030	3.07e-206	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_01031	1.47e-94	-	-	-	L	-	-	-	Helix-turn-helix domain
MADBFOCO_01032	8.28e-251	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MADBFOCO_01033	7.6e-118	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
MADBFOCO_01035	2.89e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MADBFOCO_01036	1.26e-91	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MADBFOCO_01037	2.45e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MADBFOCO_01038	3.49e-146	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MADBFOCO_01039	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MADBFOCO_01040	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MADBFOCO_01041	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MADBFOCO_01042	0.0	-	-	-	S	-	-	-	membrane
MADBFOCO_01043	1.22e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MADBFOCO_01048	5.73e-120	-	-	-	S	-	-	-	VanZ like family
MADBFOCO_01049	3.98e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MADBFOCO_01050	8.35e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MADBFOCO_01051	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MADBFOCO_01052	6.15e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MADBFOCO_01053	2.04e-95	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MADBFOCO_01054	1.18e-55	-	-	-	-	-	-	-	-
MADBFOCO_01055	2.17e-108	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MADBFOCO_01056	2.53e-240	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MADBFOCO_01057	1.16e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MADBFOCO_01059	1.32e-50	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MADBFOCO_01060	2.87e-47	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MADBFOCO_01061	2.26e-163	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MADBFOCO_01062	3.26e-90	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MADBFOCO_01063	7.74e-61	-	-	-	G	-	-	-	Major Facilitator Superfamily
MADBFOCO_01064	2.47e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
MADBFOCO_01065	1.68e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MADBFOCO_01066	1.1e-108	-	-	-	-	-	-	-	-
MADBFOCO_01067	5.67e-24	-	-	-	C	-	-	-	FMN_bind
MADBFOCO_01068	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MADBFOCO_01069	6.08e-136	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MADBFOCO_01070	9.93e-266	pbpX1	-	-	V	-	-	-	Beta-lactamase
MADBFOCO_01071	2.36e-168	-	-	-	-	-	-	-	-
MADBFOCO_01072	2.98e-31	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MADBFOCO_01073	2.72e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MADBFOCO_01074	3.93e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MADBFOCO_01075	3.3e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MADBFOCO_01076	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MADBFOCO_01077	4.18e-315	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MADBFOCO_01078	3.14e-312	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MADBFOCO_01079	7.97e-25	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_01080	1.5e-228	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_01081	3.93e-73	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MADBFOCO_01082	3.44e-152	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MADBFOCO_01084	2.49e-53	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MADBFOCO_01085	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MADBFOCO_01086	3.78e-34	-	-	-	-	-	-	-	-
MADBFOCO_01088	3.12e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MADBFOCO_01089	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MADBFOCO_01091	7.78e-79	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_01092	5.76e-18	-	-	-	S	-	-	-	YSIRK type signal peptide
MADBFOCO_01093	1.45e-54	-	-	-	S	-	-	-	Fic/DOC family
MADBFOCO_01094	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MADBFOCO_01095	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MADBFOCO_01096	2.25e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MADBFOCO_01097	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MADBFOCO_01098	2.64e-243	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MADBFOCO_01099	8.86e-29	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MADBFOCO_01100	1.33e-58	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MADBFOCO_01101	3.8e-84	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MADBFOCO_01102	2.4e-76	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MADBFOCO_01103	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MADBFOCO_01104	3.91e-272	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MADBFOCO_01105	6.03e-53	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_01106	2.04e-171	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_01107	1.46e-110	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
MADBFOCO_01108	1.03e-61	-	-	-	-	-	-	-	-
MADBFOCO_01109	3.11e-38	-	-	-	-	-	-	-	-
MADBFOCO_01110	8.78e-155	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MADBFOCO_01111	2.3e-168	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
MADBFOCO_01113	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MADBFOCO_01114	4.17e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MADBFOCO_01115	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MADBFOCO_01116	1.78e-207	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MADBFOCO_01117	2.6e-96	-	-	-	-	-	-	-	-
MADBFOCO_01118	1.05e-112	-	-	-	-	-	-	-	-
MADBFOCO_01119	3.82e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MADBFOCO_01120	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MADBFOCO_01121	6.79e-146	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MADBFOCO_01122	2.84e-108	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MADBFOCO_01123	2.79e-54	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MADBFOCO_01124	1.76e-127	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MADBFOCO_01125	4.46e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MADBFOCO_01126	1.11e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MADBFOCO_01127	7.75e-232	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MADBFOCO_01128	1.28e-115	cvpA	-	-	S	-	-	-	Colicin V production protein
MADBFOCO_01129	6.6e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MADBFOCO_01130	3.28e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MADBFOCO_01131	1.43e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MADBFOCO_01132	1.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MADBFOCO_01133	6.38e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MADBFOCO_01134	4.85e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MADBFOCO_01135	4.62e-179	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MADBFOCO_01136	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_01137	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MADBFOCO_01138	2.9e-157	vanR	-	-	K	-	-	-	response regulator
MADBFOCO_01139	3.1e-268	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MADBFOCO_01140	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MADBFOCO_01141	6.67e-187	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MADBFOCO_01142	4.24e-144	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MADBFOCO_01143	3.5e-93	-	-	-	S	-	-	-	Enterocin A Immunity
MADBFOCO_01144	2.72e-101	-	-	-	-	-	-	-	-
MADBFOCO_01145	1.97e-27	-	-	-	-	-	-	-	-
MADBFOCO_01146	7.34e-15	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MADBFOCO_01147	3.75e-98	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MADBFOCO_01148	2.71e-128	-	-	-	-	-	-	-	-
MADBFOCO_01149	2.63e-123	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MADBFOCO_01150	2.95e-145	-	-	-	KLT	-	-	-	serine threonine protein kinase
MADBFOCO_01151	4.42e-61	-	-	-	-	-	-	-	-
MADBFOCO_01152	3.28e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MADBFOCO_01153	4.5e-151	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
MADBFOCO_01154	1.77e-206	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MADBFOCO_01155	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MADBFOCO_01156	9.19e-208	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MADBFOCO_01157	1.52e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MADBFOCO_01158	4.88e-131	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_01159	2.53e-96	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MADBFOCO_01160	6.53e-80	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MADBFOCO_01161	4.08e-47	-	-	-	-	-	-	-	-
MADBFOCO_01162	2.98e-20	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MADBFOCO_01163	5.3e-304	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MADBFOCO_01164	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MADBFOCO_01166	4.04e-70	-	-	-	M	-	-	-	domain protein
MADBFOCO_01168	4.72e-16	-	-	-	M	-	-	-	domain protein
MADBFOCO_01169	5.65e-176	-	-	-	S	-	-	-	YSIRK type signal peptide
MADBFOCO_01170	8.84e-52	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
MADBFOCO_01171	3.11e-67	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
MADBFOCO_01172	5.6e-32	-	-	-	-	-	-	-	-
MADBFOCO_01173	4.29e-175	-	-	-	-	-	-	-	-
MADBFOCO_01174	1.57e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MADBFOCO_01175	1.49e-105	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MADBFOCO_01176	4.62e-131	-	-	-	G	-	-	-	Aldose 1-epimerase
MADBFOCO_01177	5.03e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MADBFOCO_01178	4.72e-147	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MADBFOCO_01179	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MADBFOCO_01180	6.28e-99	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_01181	2.54e-73	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_01182	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MADBFOCO_01183	2.04e-226	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01184	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
MADBFOCO_01185	4.58e-248	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MADBFOCO_01186	3.05e-21	-	-	-	-	-	-	-	-
MADBFOCO_01187	3.77e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MADBFOCO_01188	9.65e-193	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MADBFOCO_01189	6.63e-88	-	-	-	C	-	-	-	Flavodoxin
MADBFOCO_01190	1.97e-21	-	-	-	C	-	-	-	Flavodoxin
MADBFOCO_01191	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MADBFOCO_01192	1.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
MADBFOCO_01193	3.4e-126	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MADBFOCO_01194	1.23e-120	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MADBFOCO_01195	1.83e-27	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MADBFOCO_01196	8.58e-112	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MADBFOCO_01197	6.75e-63	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MADBFOCO_01198	2.92e-42	-	-	-	S	-	-	-	Enterocin A Immunity
MADBFOCO_01199	2.72e-42	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_01200	1.29e-116	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MADBFOCO_01201	4.3e-277	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MADBFOCO_01202	6.15e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MADBFOCO_01203	1.29e-192	yycI	-	-	S	-	-	-	YycH protein
MADBFOCO_01204	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
MADBFOCO_01205	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MADBFOCO_01207	5.25e-37	-	-	-	-	-	-	-	-
MADBFOCO_01208	1.83e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MADBFOCO_01209	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MADBFOCO_01210	6.31e-256	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MADBFOCO_01211	1.14e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MADBFOCO_01212	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MADBFOCO_01213	1.24e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MADBFOCO_01214	6.35e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MADBFOCO_01215	1.4e-205	-	-	-	-	-	-	-	-
MADBFOCO_01216	1.64e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MADBFOCO_01217	2.24e-245	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01218	1.02e-33	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MADBFOCO_01219	7.18e-182	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
MADBFOCO_01220	4.75e-80	-	-	-	-	-	-	-	-
MADBFOCO_01221	2.57e-20	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MADBFOCO_01222	1.16e-304	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MADBFOCO_01223	4.6e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MADBFOCO_01225	3.4e-178	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_01226	8.55e-99	-	-	-	-	-	-	-	-
MADBFOCO_01227	3.79e-136	-	-	-	-	-	-	-	-
MADBFOCO_01228	5.46e-189	-	-	-	D	-	-	-	Ftsk spoiiie family protein
MADBFOCO_01229	2.33e-199	-	-	-	S	-	-	-	Replication initiation factor
MADBFOCO_01230	2.5e-77	-	-	-	-	-	-	-	-
MADBFOCO_01231	1.71e-37	-	-	-	-	-	-	-	-
MADBFOCO_01232	9.84e-73	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MADBFOCO_01233	6.72e-316	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
MADBFOCO_01234	5.52e-71	-	-	-	-	-	-	-	-
MADBFOCO_01235	1.28e-79	-	-	-	-	-	-	-	-
MADBFOCO_01236	5.86e-156	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
MADBFOCO_01237	1.26e-07	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
MADBFOCO_01238	4.21e-19	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MADBFOCO_01239	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MADBFOCO_01240	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MADBFOCO_01241	2.68e-104	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MADBFOCO_01242	5.34e-17	-	-	-	-	-	-	-	-
MADBFOCO_01243	3.07e-23	-	-	-	-	-	-	-	-
MADBFOCO_01244	3.8e-253	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01245	1.25e-188	-	-	-	I	-	-	-	Acyl-transferase
MADBFOCO_01246	2.91e-86	-	-	-	-	-	-	-	-
MADBFOCO_01247	8.43e-19	-	-	-	-	-	-	-	-
MADBFOCO_01248	2.05e-112	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_01249	8.3e-53	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_01250	7.53e-203	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MADBFOCO_01251	1.07e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
MADBFOCO_01252	1.29e-13	-	-	-	M	-	-	-	Glycosyl transferase family 8
MADBFOCO_01253	1.35e-195	-	-	-	M	-	-	-	Glycosyl transferase family 8
MADBFOCO_01254	1.6e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MADBFOCO_01255	5.04e-47	-	-	-	S	-	-	-	Cytochrome b5
MADBFOCO_01256	7.68e-125	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MADBFOCO_01257	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MADBFOCO_01258	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MADBFOCO_01259	5.43e-16	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MADBFOCO_01262	3.53e-227	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MADBFOCO_01265	1.06e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MADBFOCO_01266	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MADBFOCO_01267	1.12e-84	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MADBFOCO_01268	3.31e-136	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
MADBFOCO_01269	3.55e-256	-	-	-	S	-	-	-	Protein of unknown function DUF262
MADBFOCO_01270	7.64e-39	-	-	-	S	-	-	-	Protein of unknown function DUF262
MADBFOCO_01271	5.35e-287	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MADBFOCO_01272	4.11e-32	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MADBFOCO_01273	4.52e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MADBFOCO_01274	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MADBFOCO_01275	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MADBFOCO_01276	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MADBFOCO_01277	1.53e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MADBFOCO_01278	5.23e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MADBFOCO_01279	1.19e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MADBFOCO_01287	4.14e-81	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MADBFOCO_01288	1.8e-157	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MADBFOCO_01289	4.27e-274	-	-	-	-	-	-	-	-
MADBFOCO_01292	7.68e-173	slpX	-	-	S	-	-	-	SLAP domain
MADBFOCO_01293	9.63e-14	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MADBFOCO_01294	9.34e-98	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MADBFOCO_01295	4.12e-24	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MADBFOCO_01297	1.9e-19	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
MADBFOCO_01298	1.97e-316	tnp2	-	-	L	ko:K07485	-	ko00000	Transposase
MADBFOCO_01299	1.44e-106	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_01301	3.19e-33	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MADBFOCO_01304	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MADBFOCO_01305	2.53e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MADBFOCO_01306	5.57e-220	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MADBFOCO_01307	1.31e-205	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MADBFOCO_01308	4.63e-11	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MADBFOCO_01309	1.77e-144	-	-	-	EGP	ko:K08152	-	ko00000,ko02000	Major Facilitator Superfamily
MADBFOCO_01310	2.48e-36	-	-	-	L	ko:K02612	ko00360,ko01120,map00360,map01120	ko00000,ko00001	metal-sulfur cluster biosynthetic enzyme
MADBFOCO_01311	2.63e-207	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_01312	1.76e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_01313	1.12e-127	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_01314	4.13e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MADBFOCO_01315	2.49e-21	-	-	-	-	-	-	-	-
MADBFOCO_01316	4.97e-93	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MADBFOCO_01317	1.52e-43	-	-	-	-	-	-	-	-
MADBFOCO_01318	3.96e-89	-	-	-	-	-	-	-	-
MADBFOCO_01319	2.07e-37	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MADBFOCO_01320	1.02e-61	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MADBFOCO_01321	1.01e-27	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MADBFOCO_01322	3.74e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MADBFOCO_01323	2.65e-157	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MADBFOCO_01324	2.39e-33	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01325	2.35e-286	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MADBFOCO_01326	2.59e-83	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily
MADBFOCO_01327	7.54e-51	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MADBFOCO_01328	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MADBFOCO_01329	6.37e-23	-	-	-	K	-	-	-	Penicillinase repressor
MADBFOCO_01330	8.14e-125	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family
MADBFOCO_01331	1.58e-269	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_01332	5.07e-129	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MADBFOCO_01333	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MADBFOCO_01334	8.52e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MADBFOCO_01335	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MADBFOCO_01336	6.75e-62	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MADBFOCO_01337	6.71e-156	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MADBFOCO_01338	5.02e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MADBFOCO_01339	9.2e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MADBFOCO_01340	4.47e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MADBFOCO_01341	2.34e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MADBFOCO_01342	1.15e-44	-	-	-	S	ko:K18918	-	ko00000,ko02048,ko03000	RelB antitoxin
MADBFOCO_01343	2.53e-134	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MADBFOCO_01344	1.29e-261	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MADBFOCO_01346	5.33e-304	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MADBFOCO_01347	0.0	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MADBFOCO_01348	0.0	-	-	-	-	-	-	-	-
MADBFOCO_01349	7.07e-106	-	-	-	-	-	-	-	-
MADBFOCO_01350	1.05e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MADBFOCO_01351	8.54e-87	-	-	-	S	-	-	-	ASCH domain
MADBFOCO_01352	2.16e-16	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MADBFOCO_01353	3.11e-41	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MADBFOCO_01354	8.58e-180	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MADBFOCO_01355	5.09e-28	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MADBFOCO_01356	1.35e-70	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_01357	1.81e-54	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_01358	3.61e-26	-	-	-	V	-	-	-	Restriction endonuclease
MADBFOCO_01359	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MADBFOCO_01360	7.64e-311	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MADBFOCO_01361	8.9e-51	-	-	-	-	-	-	-	-
MADBFOCO_01362	1.37e-70	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MADBFOCO_01363	1.35e-114	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MADBFOCO_01364	4.26e-75	-	-	-	-	-	-	-	-
MADBFOCO_01365	2.66e-307	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MADBFOCO_01366	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MADBFOCO_01367	9.37e-169	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MADBFOCO_01368	6.68e-81	-	-	-	S	-	-	-	SdpI/YhfL protein family
MADBFOCO_01369	5.58e-222	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MADBFOCO_01370	8.78e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MADBFOCO_01371	5.55e-30	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MADBFOCO_01372	1.91e-83	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MADBFOCO_01373	3.88e-23	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MADBFOCO_01375	1.14e-79	-	-	-	K	-	-	-	LysR substrate binding domain
MADBFOCO_01376	1.48e-10	-	-	-	K	-	-	-	LysR substrate binding domain
MADBFOCO_01377	3.51e-30	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
MADBFOCO_01378	3.87e-12	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MADBFOCO_01379	2.48e-175	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MADBFOCO_01380	1.24e-178	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MADBFOCO_01381	7.15e-73	-	-	-	-	-	-	-	-
MADBFOCO_01382	1.34e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MADBFOCO_01385	1.3e-199	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MADBFOCO_01386	8.6e-108	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MADBFOCO_01387	3.74e-35	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_01388	5.51e-115	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MADBFOCO_01389	1.22e-89	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MADBFOCO_01390	2.92e-190	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MADBFOCO_01391	2.16e-148	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MADBFOCO_01392	7.77e-36	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MADBFOCO_01394	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MADBFOCO_01395	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MADBFOCO_01396	2.71e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MADBFOCO_01397	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MADBFOCO_01398	9.47e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MADBFOCO_01399	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_01400	4.76e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MADBFOCO_01401	6.62e-48	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MADBFOCO_01402	1.83e-187	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MADBFOCO_01403	1.05e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MADBFOCO_01404	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MADBFOCO_01405	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MADBFOCO_01406	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MADBFOCO_01407	3.69e-187	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MADBFOCO_01408	1.21e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MADBFOCO_01409	7.78e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MADBFOCO_01410	1.29e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MADBFOCO_01411	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MADBFOCO_01412	7.49e-74	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MADBFOCO_01413	2.11e-82	-	-	-	S	-	-	-	Enterocin A Immunity
MADBFOCO_01414	1.58e-164	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MADBFOCO_01415	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MADBFOCO_01416	7.86e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
MADBFOCO_01418	9.42e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MADBFOCO_01419	2.22e-30	-	-	-	-	-	-	-	-
MADBFOCO_01420	1.89e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MADBFOCO_01421	8.92e-77	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MADBFOCO_01422	1.65e-285	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MADBFOCO_01423	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MADBFOCO_01424	1.49e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MADBFOCO_01425	4.09e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MADBFOCO_01426	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MADBFOCO_01427	1.55e-79	-	-	-	-	-	-	-	-
MADBFOCO_01428	1.45e-53	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MADBFOCO_01430	4.31e-21	repA	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
MADBFOCO_01432	4.77e-104	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MADBFOCO_01433	2.45e-64	-	-	-	-	-	-	-	-
MADBFOCO_01434	3.9e-91	-	-	-	L	-	-	-	manually curated
MADBFOCO_01435	2.16e-29	-	-	-	L	-	-	-	Phage integrase family
MADBFOCO_01436	4.96e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MADBFOCO_01437	2.68e-84	-	-	-	-	-	-	-	-
MADBFOCO_01438	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MADBFOCO_01439	7.18e-184	-	-	-	F	-	-	-	Phosphorylase superfamily
MADBFOCO_01440	1.31e-86	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
MADBFOCO_01442	6.41e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MADBFOCO_01443	5.46e-74	-	-	-	-	-	-	-	-
MADBFOCO_01444	3.06e-101	-	-	-	-	-	-	-	-
MADBFOCO_01445	1.51e-48	-	-	-	-	-	-	-	-
MADBFOCO_01446	4.04e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MADBFOCO_01447	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MADBFOCO_01448	1.63e-67	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MADBFOCO_01449	3.42e-197	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MADBFOCO_01450	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MADBFOCO_01451	7.75e-61	-	-	-	-	-	-	-	-
MADBFOCO_01452	3.7e-57	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
MADBFOCO_01453	2.14e-235	-	-	-	U	-	-	-	FFAT motif binding
MADBFOCO_01454	2.62e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MADBFOCO_01455	2.47e-24	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
MADBFOCO_01456	6.63e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MADBFOCO_01457	5.84e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MADBFOCO_01458	9.84e-183	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MADBFOCO_01459	1.36e-151	-	-	-	L	-	-	-	Integrase
MADBFOCO_01461	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
MADBFOCO_01462	3.79e-63	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MADBFOCO_01463	4.2e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MADBFOCO_01464	2.6e-75	-	-	-	S	-	-	-	Alpha beta hydrolase
MADBFOCO_01465	2.67e-48	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MADBFOCO_01466	1.44e-182	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MADBFOCO_01467	2.73e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MADBFOCO_01468	1.3e-80	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
MADBFOCO_01470	1.03e-82	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
MADBFOCO_01471	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MADBFOCO_01473	4.13e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MADBFOCO_01474	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MADBFOCO_01476	2.66e-108	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MADBFOCO_01477	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MADBFOCO_01478	5.14e-19	-	-	-	S	-	-	-	Fic/DOC family
MADBFOCO_01479	8.65e-310	-	-	-	L	-	-	-	Probable transposase
MADBFOCO_01480	4.84e-44	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MADBFOCO_01481	1.06e-57	-	-	-	-	-	-	-	-
MADBFOCO_01482	8.86e-62	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_01483	4.85e-20	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MADBFOCO_01485	7.34e-22	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MADBFOCO_01487	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MADBFOCO_01488	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MADBFOCO_01489	1.66e-42	-	-	-	-	-	-	-	-
MADBFOCO_01490	7.71e-52	-	-	-	-	-	-	-	-
MADBFOCO_01491	1.99e-116	-	-	-	L	-	-	-	NUDIX domain
MADBFOCO_01492	5.16e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MADBFOCO_01493	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MADBFOCO_01495	2.44e-148	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MADBFOCO_01496	2.62e-136	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MADBFOCO_01497	1.61e-102	padR	-	-	K	-	-	-	Virulence activator alpha C-term
MADBFOCO_01498	9.06e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MADBFOCO_01499	1.29e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MADBFOCO_01500	1.81e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MADBFOCO_01502	1.23e-63	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MADBFOCO_01503	9.1e-44	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MADBFOCO_01504	6.49e-35	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MADBFOCO_01505	2.37e-39	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MADBFOCO_01506	1.53e-24	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MADBFOCO_01507	1.11e-15	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MADBFOCO_01508	1.13e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MADBFOCO_01509	3.56e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
MADBFOCO_01510	5.7e-75	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
MADBFOCO_01511	5.26e-34	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_01512	1.28e-48	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_01513	2.71e-25	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_01514	4.82e-42	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MADBFOCO_01515	8.96e-88	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MADBFOCO_01516	3.81e-111	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MADBFOCO_01518	1.05e-256	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MADBFOCO_01519	9.91e-68	-	-	-	-	-	-	-	-
MADBFOCO_01520	3.27e-277	-	-	-	S	-	-	-	Membrane
MADBFOCO_01521	4.13e-35	ykuL	-	-	S	-	-	-	IMP dehydrogenase activity
MADBFOCO_01522	8.09e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MADBFOCO_01523	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MADBFOCO_01524	3.59e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
MADBFOCO_01525	2.05e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MADBFOCO_01526	7.23e-45	-	3.2.1.4	GH5,GH9	M	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	domain protein
MADBFOCO_01528	1.25e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MADBFOCO_01529	1.84e-63	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MADBFOCO_01530	1.84e-166	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MADBFOCO_01532	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MADBFOCO_01533	9.74e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MADBFOCO_01534	1.96e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MADBFOCO_01535	7.6e-139	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MADBFOCO_01537	2.21e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
MADBFOCO_01538	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MADBFOCO_01539	4.21e-126	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MADBFOCO_01540	2.58e-79	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MADBFOCO_01541	8.42e-20	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MADBFOCO_01543	4.2e-30	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MADBFOCO_01544	1.32e-21	-	-	-	-	-	-	-	-
MADBFOCO_01545	1.53e-15	-	-	-	-	-	-	-	-
MADBFOCO_01546	3.85e-86	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MADBFOCO_01547	1.28e-163	-	-	-	F	-	-	-	NUDIX domain
MADBFOCO_01551	3.24e-109	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MADBFOCO_01552	6.06e-82	-	-	-	L	-	-	-	Probable transposase
MADBFOCO_01553	4.03e-25	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MADBFOCO_01555	8.5e-37	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_01556	9.4e-35	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MADBFOCO_01557	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MADBFOCO_01558	1.4e-203	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MADBFOCO_01559	1.13e-186	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MADBFOCO_01560	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MADBFOCO_01561	2.21e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MADBFOCO_01562	4.55e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MADBFOCO_01563	3.42e-209	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MADBFOCO_01564	7.02e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_01565	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MADBFOCO_01566	4.44e-203	-	-	-	-	-	-	-	-
MADBFOCO_01567	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MADBFOCO_01568	4.93e-164	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MADBFOCO_01569	7.24e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MADBFOCO_01570	4.04e-142	-	-	-	S	-	-	-	SNARE associated Golgi protein
MADBFOCO_01571	4.81e-127	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MADBFOCO_01572	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MADBFOCO_01573	4.83e-35	-	-	-	-	-	-	-	-
MADBFOCO_01575	3.25e-96	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MADBFOCO_01576	9.58e-28	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MADBFOCO_01577	6.08e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MADBFOCO_01578	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MADBFOCO_01579	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MADBFOCO_01580	1.47e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MADBFOCO_01581	1.26e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MADBFOCO_01582	1.57e-51	-	-	-	L	ko:K07496	-	ko00000	Transposase
MADBFOCO_01583	2.81e-06	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MADBFOCO_01584	1.01e-33	-	-	-	-	-	-	-	-
MADBFOCO_01585	1.96e-23	-	-	-	-	-	-	-	-
MADBFOCO_01586	3.06e-74	-	-	-	-	-	-	-	-
MADBFOCO_01588	3.78e-13	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease)
MADBFOCO_01589	2.61e-88	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MADBFOCO_01590	9.05e-08	-	-	-	-	-	-	-	-
MADBFOCO_01591	1.84e-95	-	-	-	-	-	-	-	-
MADBFOCO_01592	2.28e-113	flaR	-	-	F	-	-	-	topology modulation protein
MADBFOCO_01593	1.35e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MADBFOCO_01594	5.66e-72	-	-	-	-	-	-	-	-
MADBFOCO_01595	5.82e-35	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01596	2.43e-56	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01597	2.42e-59	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01598	5.64e-17	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01599	1.06e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
MADBFOCO_01600	5.25e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MADBFOCO_01601	5.46e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_01602	2.19e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MADBFOCO_01603	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MADBFOCO_01604	1.47e-218	-	-	-	K	-	-	-	Transcriptional regulator
MADBFOCO_01605	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MADBFOCO_01606	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MADBFOCO_01607	2.5e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MADBFOCO_01608	1.76e-258	snf	-	-	KL	-	-	-	domain protein
MADBFOCO_01609	1.7e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MADBFOCO_01610	1.52e-120	-	-	-	K	-	-	-	acetyltransferase
MADBFOCO_01611	9.8e-197	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MADBFOCO_01612	3.1e-104	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MADBFOCO_01613	1.36e-137	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MADBFOCO_01614	7.3e-53	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MADBFOCO_01615	4.51e-38	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
MADBFOCO_01616	2.55e-12	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
MADBFOCO_01617	1.16e-220	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MADBFOCO_01618	6.41e-290	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MADBFOCO_01619	7.28e-209	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MADBFOCO_01620	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MADBFOCO_01621	2.07e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MADBFOCO_01622	6.08e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MADBFOCO_01623	0.0	yhaN	-	-	L	-	-	-	AAA domain
MADBFOCO_01624	2.85e-242	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MADBFOCO_01625	6.37e-102	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MADBFOCO_01626	1.97e-200	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MADBFOCO_01627	6.03e-57	-	-	-	-	-	-	-	-
MADBFOCO_01628	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MADBFOCO_01629	1.33e-46	-	-	-	S	-	-	-	Plasmid maintenance system killer
MADBFOCO_01630	1.38e-71	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
MADBFOCO_01631	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_01632	1.13e-272	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MADBFOCO_01633	3.87e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MADBFOCO_01634	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MADBFOCO_01635	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MADBFOCO_01636	0.0	-	-	-	-	-	-	-	-
MADBFOCO_01637	3.19e-123	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MADBFOCO_01638	3.26e-128	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MADBFOCO_01639	9.54e-74	-	-	-	-	-	-	-	-
MADBFOCO_01640	0.0	-	-	-	S	-	-	-	ABC transporter
MADBFOCO_01641	1.38e-178	-	-	-	S	-	-	-	Putative threonine/serine exporter
MADBFOCO_01642	2.47e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MADBFOCO_01643	1.62e-130	-	-	-	E	-	-	-	amino acid
MADBFOCO_01644	9.08e-20	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MADBFOCO_01645	2.14e-313	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MADBFOCO_01646	2.38e-308	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MADBFOCO_01647	5.32e-166	-	-	-	-	-	-	-	-
MADBFOCO_01648	3.58e-155	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MADBFOCO_01649	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MADBFOCO_01650	1.22e-218	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MADBFOCO_01651	4.63e-277	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MADBFOCO_01652	1.71e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_01653	2.94e-138	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_01654	2.94e-282	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MADBFOCO_01655	4.81e-50	-	-	-	-	-	-	-	-
MADBFOCO_01656	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MADBFOCO_01657	4.62e-187	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01658	2.32e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MADBFOCO_01659	5.19e-67	-	-	-	-	-	-	-	-
MADBFOCO_01660	5.65e-38	-	-	-	-	-	-	-	-
MADBFOCO_01661	1.38e-163	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MADBFOCO_01664	1.38e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
MADBFOCO_01665	9.71e-317	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MADBFOCO_01666	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MADBFOCO_01667	4.08e-311	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MADBFOCO_01668	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MADBFOCO_01669	4.54e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MADBFOCO_01670	2.84e-19	-	-	-	-	-	-	-	-
MADBFOCO_01671	7.57e-210	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MADBFOCO_01672	6.09e-107	-	-	-	S	-	-	-	Peptidase family M23
MADBFOCO_01673	4.49e-195	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MADBFOCO_01674	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MADBFOCO_01675	5.12e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MADBFOCO_01676	3.51e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MADBFOCO_01677	1.25e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MADBFOCO_01678	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MADBFOCO_01679	8.01e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MADBFOCO_01680	2.22e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MADBFOCO_01681	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MADBFOCO_01682	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MADBFOCO_01683	3.66e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MADBFOCO_01684	3.58e-162	-	-	-	S	-	-	-	Peptidase family M23
MADBFOCO_01685	2.2e-39	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MADBFOCO_01686	4.48e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MADBFOCO_01687	2.43e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MADBFOCO_01688	2.98e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MADBFOCO_01689	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MADBFOCO_01690	3.13e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MADBFOCO_01691	2.37e-187	-	-	-	-	-	-	-	-
MADBFOCO_01692	9.72e-189	-	-	-	-	-	-	-	-
MADBFOCO_01693	2.05e-178	-	-	-	-	-	-	-	-
MADBFOCO_01694	3.03e-13	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MADBFOCO_01695	6.04e-41	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MADBFOCO_01696	3.71e-142	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MADBFOCO_01697	7.83e-38	-	-	-	-	-	-	-	-
MADBFOCO_01698	7.35e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MADBFOCO_01699	1.83e-180	-	-	-	-	-	-	-	-
MADBFOCO_01700	3.53e-228	-	-	-	-	-	-	-	-
MADBFOCO_01701	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MADBFOCO_01702	1.3e-240	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MADBFOCO_01703	2.71e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MADBFOCO_01704	1.06e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MADBFOCO_01705	6.51e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MADBFOCO_01706	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MADBFOCO_01707	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MADBFOCO_01708	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MADBFOCO_01709	6.04e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MADBFOCO_01710	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MADBFOCO_01711	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MADBFOCO_01712	1.2e-145	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MADBFOCO_01713	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MADBFOCO_01714	9.14e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MADBFOCO_01715	9.69e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MADBFOCO_01716	2.24e-92	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MADBFOCO_01717	2.91e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MADBFOCO_01718	5.39e-14	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MADBFOCO_01719	1.29e-108	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MADBFOCO_01720	1.77e-101	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MADBFOCO_01721	1.4e-44	-	-	-	-	-	-	-	-
MADBFOCO_01722	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MADBFOCO_01723	7.77e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MADBFOCO_01724	5.38e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MADBFOCO_01725	7.14e-256	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MADBFOCO_01726	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MADBFOCO_01727	9.23e-305	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MADBFOCO_01728	5.54e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MADBFOCO_01729	9.85e-154	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MADBFOCO_01730	2.67e-204	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MADBFOCO_01731	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MADBFOCO_01732	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MADBFOCO_01733	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MADBFOCO_01734	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MADBFOCO_01735	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MADBFOCO_01736	7.7e-80	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MADBFOCO_01737	3.46e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MADBFOCO_01738	2e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MADBFOCO_01739	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MADBFOCO_01740	5.88e-44	-	-	-	-	-	-	-	-
MADBFOCO_01741	7.2e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MADBFOCO_01742	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MADBFOCO_01743	6.59e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MADBFOCO_01744	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MADBFOCO_01745	2.58e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MADBFOCO_01746	2.92e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MADBFOCO_01747	5.32e-266	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MADBFOCO_01748	1.01e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MADBFOCO_01749	1.08e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MADBFOCO_01750	4.26e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MADBFOCO_01751	3.08e-192	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MADBFOCO_01752	3.33e-16	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MADBFOCO_01753	1.98e-147	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MADBFOCO_01754	1.11e-302	ymfH	-	-	S	-	-	-	Peptidase M16
MADBFOCO_01755	8.89e-290	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MADBFOCO_01756	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MADBFOCO_01757	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MADBFOCO_01758	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MADBFOCO_01759	8.55e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MADBFOCO_01760	2.77e-31	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MADBFOCO_01761	1.64e-35	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MADBFOCO_01762	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MADBFOCO_01763	7.43e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MADBFOCO_01764	1.48e-151	-	-	-	S	-	-	-	SNARE associated Golgi protein
MADBFOCO_01765	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MADBFOCO_01766	1.45e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MADBFOCO_01767	9.32e-293	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MADBFOCO_01768	3.94e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MADBFOCO_01769	6.81e-250	-	-	-	D	-	-	-	nuclear chromosome segregation
MADBFOCO_01770	7.27e-132	-	-	-	M	-	-	-	LysM domain protein
MADBFOCO_01771	5.26e-19	-	-	-	-	-	-	-	-
MADBFOCO_01773	0.0	-	-	-	S	-	-	-	PglZ domain
MADBFOCO_01774	0.0	-	-	-	-	-	-	-	-
MADBFOCO_01775	1.86e-16	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MADBFOCO_01776	3.68e-108	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MADBFOCO_01777	1.17e-150	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_01778	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MADBFOCO_01779	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MADBFOCO_01780	5.81e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MADBFOCO_01781	2.35e-303	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MADBFOCO_01782	2.84e-131	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
MADBFOCO_01783	9.88e-89	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
MADBFOCO_01784	1.53e-237	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MADBFOCO_01785	8.99e-269	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MADBFOCO_01786	2.94e-316	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MADBFOCO_01787	3.47e-13	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MADBFOCO_01788	1.71e-111	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
MADBFOCO_01789	8.05e-182	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MADBFOCO_01790	1.74e-114	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
MADBFOCO_01791	7.76e-118	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
MADBFOCO_01792	9.83e-193	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
MADBFOCO_01793	2.73e-69	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
MADBFOCO_01794	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
MADBFOCO_01795	9.81e-252	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MADBFOCO_01796	1.42e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
MADBFOCO_01797	8.09e-235	-	-	-	S	-	-	-	AAA domain
MADBFOCO_01798	4e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MADBFOCO_01799	1.16e-31	-	-	-	-	-	-	-	-
MADBFOCO_01800	2.52e-207	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MADBFOCO_01801	6.64e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MADBFOCO_01802	1.81e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MADBFOCO_01803	2.01e-18	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MADBFOCO_01804	8.02e-85	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MADBFOCO_01805	1.22e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MADBFOCO_01806	1.93e-79	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MADBFOCO_01807	1.01e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MADBFOCO_01808	2.27e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MADBFOCO_01809	3.86e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MADBFOCO_01810	4.28e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MADBFOCO_01811	5.28e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MADBFOCO_01812	6.9e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MADBFOCO_01813	3.16e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MADBFOCO_01814	4.41e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MADBFOCO_01815	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MADBFOCO_01816	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MADBFOCO_01817	3.15e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MADBFOCO_01818	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MADBFOCO_01819	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MADBFOCO_01820	5.1e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MADBFOCO_01821	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MADBFOCO_01822	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MADBFOCO_01823	2.63e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MADBFOCO_01824	1.28e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MADBFOCO_01825	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MADBFOCO_01826	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MADBFOCO_01827	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MADBFOCO_01828	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MADBFOCO_01829	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MADBFOCO_01830	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MADBFOCO_01831	6.37e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MADBFOCO_01832	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MADBFOCO_01833	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MADBFOCO_01834	7.45e-158	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MADBFOCO_01835	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MADBFOCO_01836	4.33e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MADBFOCO_01837	5.7e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MADBFOCO_01838	4.67e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MADBFOCO_01839	3.85e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MADBFOCO_01840	3.29e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MADBFOCO_01841	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MADBFOCO_01842	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MADBFOCO_01843	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MADBFOCO_01844	7.28e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MADBFOCO_01845	4.15e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MADBFOCO_01846	4.46e-226	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MADBFOCO_01847	3.15e-311	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MADBFOCO_01848	2.32e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MADBFOCO_01849	1.6e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MADBFOCO_01850	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MADBFOCO_01851	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MADBFOCO_01852	4.69e-199	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MADBFOCO_01853	5.41e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MADBFOCO_01854	4.72e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MADBFOCO_01855	7.5e-34	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MADBFOCO_01856	7.62e-07	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MADBFOCO_01857	1.62e-62	-	-	-	-	-	-	-	-
MADBFOCO_01858	2.31e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MADBFOCO_01859	2.8e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MADBFOCO_01860	2.04e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MADBFOCO_01861	1.59e-158	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MADBFOCO_01862	6.01e-32	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MADBFOCO_01863	5.15e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MADBFOCO_01864	2.27e-198	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MADBFOCO_01865	1.72e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MADBFOCO_01866	3.48e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MADBFOCO_01867	2.9e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MADBFOCO_01868	2.66e-310	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MADBFOCO_01869	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MADBFOCO_01870	4.12e-254	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MADBFOCO_01871	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MADBFOCO_01872	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MADBFOCO_01873	4.51e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MADBFOCO_01874	1.01e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MADBFOCO_01875	2.92e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MADBFOCO_01876	5.89e-280	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MADBFOCO_01877	4.1e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MADBFOCO_01878	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MADBFOCO_01879	1.38e-176	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MADBFOCO_01880	1.32e-244	-	-	-	G	-	-	-	Major Facilitator Superfamily
MADBFOCO_01881	3.95e-28	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MADBFOCO_01882	2.89e-148	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MADBFOCO_01884	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MADBFOCO_01885	1.81e-109	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MADBFOCO_01886	1.53e-55	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MADBFOCO_01887	1.25e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MADBFOCO_01888	9.63e-216	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MADBFOCO_01889	1.86e-244	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MADBFOCO_01890	1.29e-61	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MADBFOCO_01891	2.4e-118	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MADBFOCO_01892	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MADBFOCO_01893	4.1e-84	fusA1	-	-	J	-	-	-	elongation factor G
MADBFOCO_01894	2.1e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
MADBFOCO_01895	4.52e-138	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01896	1.78e-74	-	-	-	S	-	-	-	SLAP domain
MADBFOCO_01897	6.58e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MADBFOCO_01898	1.7e-234	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MADBFOCO_01899	1.88e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MADBFOCO_01900	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MADBFOCO_01901	1.67e-57	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MADBFOCO_01902	3.96e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MADBFOCO_01903	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MADBFOCO_01904	6e-268	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MADBFOCO_01905	1.28e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MADBFOCO_01906	3.1e-41	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MADBFOCO_01909	3.49e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MADBFOCO_01910	4.19e-13	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MADBFOCO_01911	4.64e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MADBFOCO_01912	3.28e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MADBFOCO_01913	2.54e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MADBFOCO_01914	3.8e-124	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MADBFOCO_01915	1.97e-125	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MADBFOCO_01916	5.24e-41	-	-	-	-	-	-	-	-
MADBFOCO_01917	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MADBFOCO_01919	5.15e-236	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MADBFOCO_01920	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MADBFOCO_01921	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MADBFOCO_01922	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_01923	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MADBFOCO_01924	3.53e-203	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MADBFOCO_01925	7.39e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MADBFOCO_01926	6.09e-231	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MADBFOCO_01927	6.3e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MADBFOCO_01928	5.34e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MADBFOCO_01929	3.85e-235	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MADBFOCO_01930	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MADBFOCO_01931	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MADBFOCO_01932	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MADBFOCO_01933	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MADBFOCO_01934	1.06e-68	-	-	-	-	-	-	-	-
MADBFOCO_01935	8.07e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MADBFOCO_01936	2.51e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MADBFOCO_01937	1.59e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MADBFOCO_01938	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MADBFOCO_01939	8.11e-190	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MADBFOCO_01940	4.49e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MADBFOCO_01941	7.96e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MADBFOCO_01942	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MADBFOCO_01943	1.67e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MADBFOCO_01944	7.26e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MADBFOCO_01945	6.84e-57	-	-	-	S	-	-	-	ASCH
MADBFOCO_01946	3.93e-28	-	-	-	S	-	-	-	ASCH
MADBFOCO_01947	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MADBFOCO_01948	8.78e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MADBFOCO_01949	6.71e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MADBFOCO_01950	4.4e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MADBFOCO_01951	5.59e-251	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MADBFOCO_01952	1.4e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MADBFOCO_01953	5.2e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MADBFOCO_01954	6.6e-91	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MADBFOCO_01955	1.04e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MADBFOCO_01956	6.96e-263	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MADBFOCO_01957	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MADBFOCO_01958	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MADBFOCO_01959	2.41e-308	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MADBFOCO_01960	1.97e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MADBFOCO_01961	2.83e-167	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MADBFOCO_01962	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MADBFOCO_01963	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MADBFOCO_01964	8.36e-275	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MADBFOCO_01966	1.05e-228	lipA	-	-	I	-	-	-	Carboxylesterase family
MADBFOCO_01967	2.21e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MADBFOCO_01968	7.06e-30	-	-	-	-	-	-	-	-
MADBFOCO_01969	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MADBFOCO_01970	5.88e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MADBFOCO_01971	1.9e-65	-	-	-	-	-	-	-	-
MADBFOCO_01972	1.83e-194	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MADBFOCO_01974	9.14e-50	-	-	-	-	-	-	-	-
MADBFOCO_01975	2.11e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MADBFOCO_01978	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MADBFOCO_01979	1.21e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MADBFOCO_01980	5.18e-234	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MADBFOCO_01981	1.25e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MADBFOCO_01982	2.95e-239	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MADBFOCO_01983	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MADBFOCO_01984	2.91e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MADBFOCO_01985	2.16e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MADBFOCO_01986	1.14e-84	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MADBFOCO_01987	4.8e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MADBFOCO_01988	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MADBFOCO_01989	9.99e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MADBFOCO_01990	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MADBFOCO_01991	6.02e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MADBFOCO_01992	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MADBFOCO_01993	7.12e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MADBFOCO_01994	1.31e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MADBFOCO_01995	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MADBFOCO_01996	8.71e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MADBFOCO_01997	1.34e-103	uspA	-	-	T	-	-	-	universal stress protein
MADBFOCO_01998	4.53e-55	-	-	-	-	-	-	-	-
MADBFOCO_01999	3.94e-308	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MADBFOCO_02000	1.83e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MADBFOCO_02001	8.8e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MADBFOCO_02002	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MADBFOCO_02003	7.44e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MADBFOCO_02004	1.13e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MADBFOCO_02005	3.77e-180	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_02006	4.46e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MADBFOCO_02007	8.44e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
MADBFOCO_02008	1.33e-84	-	-	-	-	-	-	-	-
MADBFOCO_02009	4.67e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MADBFOCO_02010	7.57e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
MADBFOCO_02011	1.47e-124	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MADBFOCO_02012	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_02013	9.14e-49	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_02014	2.93e-16	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MADBFOCO_02015	3.1e-249	-	-	-	S	-	-	-	DUF218 domain
MADBFOCO_02016	2.61e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MADBFOCO_02017	1.83e-63	-	-	-	-	-	-	-	-
MADBFOCO_02018	2.1e-205	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MADBFOCO_02019	3.77e-114	-	-	-	S	-	-	-	Putative adhesin
MADBFOCO_02020	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MADBFOCO_02021	3.93e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MADBFOCO_02022	9e-66	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MADBFOCO_02023	1.34e-261	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MADBFOCO_02024	0.0	cadA	-	-	P	-	-	-	P-type ATPase