ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KHGMHEMB_00001 2.08e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHGMHEMB_00002 7.18e-86 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHGMHEMB_00003 2.61e-195 - - - L - - - Phage integrase, N-terminal SAM-like domain
KHGMHEMB_00005 4.96e-108 - - - S - - - Domain of unknown function (DUF5067)
KHGMHEMB_00006 4.45e-83 - - - - - - - -
KHGMHEMB_00008 1.07e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHGMHEMB_00009 2.5e-184 - - - F - - - Phosphorylase superfamily
KHGMHEMB_00010 1.34e-98 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
KHGMHEMB_00012 6.41e-106 - - - K - - - Acetyltransferase (GNAT) domain
KHGMHEMB_00013 1.11e-71 - - - - - - - -
KHGMHEMB_00014 5.9e-05 - - - - - - - -
KHGMHEMB_00015 4.29e-88 - - - - - - - -
KHGMHEMB_00016 5.32e-73 yitW - - S - - - Iron-sulfur cluster assembly protein
KHGMHEMB_00017 6.86e-198 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KHGMHEMB_00018 1.4e-160 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
KHGMHEMB_00019 1.1e-31 - - - - - - - -
KHGMHEMB_00020 3.2e-64 - - - - - - - -
KHGMHEMB_00021 9.8e-268 - - - G - - - Major Facilitator Superfamily
KHGMHEMB_00022 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_00023 8.41e-145 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_00024 5.91e-39 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_00025 1.44e-71 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_00026 1.15e-31 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00027 2.42e-59 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00028 2.43e-56 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00029 5.82e-35 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00030 5.66e-72 - - - - - - - -
KHGMHEMB_00031 1.35e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
KHGMHEMB_00032 1.81e-102 flaR - - F - - - topology modulation protein
KHGMHEMB_00033 1.84e-95 - - - - - - - -
KHGMHEMB_00034 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHGMHEMB_00035 4.81e-127 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHGMHEMB_00036 4.04e-142 - - - S - - - SNARE associated Golgi protein
KHGMHEMB_00037 7.24e-199 - - - I - - - alpha/beta hydrolase fold
KHGMHEMB_00038 4.93e-164 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KHGMHEMB_00039 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KHGMHEMB_00040 4.44e-203 - - - - - - - -
KHGMHEMB_00041 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
KHGMHEMB_00042 7.02e-128 yobS - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_00043 3.42e-209 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHGMHEMB_00044 2.02e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KHGMHEMB_00045 3.66e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHGMHEMB_00046 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
KHGMHEMB_00047 6.84e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHGMHEMB_00048 1.4e-203 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
KHGMHEMB_00049 9.81e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHGMHEMB_00050 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_00051 2.53e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KHGMHEMB_00052 5.57e-220 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
KHGMHEMB_00053 3.75e-205 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_00054 8.22e-75 - - - L - - - Probable transposase
KHGMHEMB_00055 4.76e-55 - - - - - - - -
KHGMHEMB_00057 5.53e-151 - - - L - - - Integrase
KHGMHEMB_00059 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
KHGMHEMB_00060 1.02e-82 - - - K - - - Acetyltransferase (GNAT) family
KHGMHEMB_00061 4.87e-76 - - - S - - - Alpha beta hydrolase
KHGMHEMB_00062 3.33e-49 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KHGMHEMB_00063 2.82e-185 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KHGMHEMB_00064 7.13e-63 - 1.1.1.3 - T ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 phosphoserine phosphatase activity
KHGMHEMB_00065 1.53e-143 - - - K - - - helix_turn_helix, mercury resistance
KHGMHEMB_00066 4.19e-13 - - - S ko:K07133 - ko00000 cog cog1373
KHGMHEMB_00067 3.91e-216 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
KHGMHEMB_00068 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KHGMHEMB_00069 4.9e-100 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHGMHEMB_00070 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KHGMHEMB_00071 1.54e-84 - - - S - - - SLAP domain
KHGMHEMB_00072 4.55e-67 - - - - - - - -
KHGMHEMB_00073 2.72e-101 - - - - - - - -
KHGMHEMB_00074 1.48e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHGMHEMB_00075 1.54e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KHGMHEMB_00076 2.46e-224 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KHGMHEMB_00077 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KHGMHEMB_00078 3.44e-130 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KHGMHEMB_00079 5.56e-245 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KHGMHEMB_00080 3.35e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHGMHEMB_00081 6.08e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KHGMHEMB_00082 1.72e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
KHGMHEMB_00083 4.04e-265 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KHGMHEMB_00084 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KHGMHEMB_00085 1.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHGMHEMB_00086 9e-46 ykzG - - S - - - Belongs to the UPF0356 family
KHGMHEMB_00087 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHGMHEMB_00088 1.83e-37 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KHGMHEMB_00089 1.6e-135 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KHGMHEMB_00090 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHGMHEMB_00091 1.56e-145 - - - S - - - repeat protein
KHGMHEMB_00092 5.5e-162 pgm - - G - - - Phosphoglycerate mutase family
KHGMHEMB_00093 1.14e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHGMHEMB_00094 2.01e-74 XK27_04120 - - S - - - Putative amino acid metabolism
KHGMHEMB_00095 5.65e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KHGMHEMB_00096 2.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHGMHEMB_00097 3.67e-56 - - - - - - - -
KHGMHEMB_00098 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KHGMHEMB_00099 1.15e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHGMHEMB_00100 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHGMHEMB_00101 8.69e-166 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KHGMHEMB_00102 4.01e-192 ylmH - - S - - - S4 domain protein
KHGMHEMB_00103 5.07e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
KHGMHEMB_00104 2.88e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHGMHEMB_00105 1.04e-265 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHGMHEMB_00106 3.43e-301 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHGMHEMB_00107 1.28e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHGMHEMB_00108 1.72e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHGMHEMB_00109 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHGMHEMB_00110 1.88e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHGMHEMB_00111 9.04e-56 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KHGMHEMB_00112 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KHGMHEMB_00113 1.88e-71 ftsL - - D - - - Cell division protein FtsL
KHGMHEMB_00114 1.15e-234 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHGMHEMB_00115 6.58e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KHGMHEMB_00116 1.16e-118 - - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
KHGMHEMB_00117 3.5e-249 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KHGMHEMB_00118 2.69e-313 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHGMHEMB_00119 1.7e-314 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KHGMHEMB_00120 8.32e-56 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KHGMHEMB_00121 1.84e-63 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
KHGMHEMB_00122 3.06e-199 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KHGMHEMB_00123 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHGMHEMB_00124 2.21e-39 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHGMHEMB_00125 1.23e-120 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
KHGMHEMB_00126 3.4e-126 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
KHGMHEMB_00127 1.97e-140 pncA - - Q - - - Isochorismatase family
KHGMHEMB_00128 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHGMHEMB_00129 4.73e-102 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
KHGMHEMB_00130 7.97e-67 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KHGMHEMB_00131 1.09e-75 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KHGMHEMB_00132 0.0 - - - - - - - -
KHGMHEMB_00133 5.09e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_00134 3.92e-53 - - - - - - - -
KHGMHEMB_00135 7.16e-23 - - - - - - - -
KHGMHEMB_00136 2.94e-52 - - - - - - - -
KHGMHEMB_00137 8.79e-48 - - - - - - - -
KHGMHEMB_00138 4.3e-186 - - - D - - - Ftsk spoiiie family protein
KHGMHEMB_00139 1.23e-185 - - - S - - - Replication initiation factor
KHGMHEMB_00140 1.39e-74 - - - - - - - -
KHGMHEMB_00141 1.71e-37 - - - - - - - -
KHGMHEMB_00142 7.08e-290 - - - L - - - Belongs to the 'phage' integrase family
KHGMHEMB_00145 5.23e-45 - - - - - - - -
KHGMHEMB_00147 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KHGMHEMB_00148 3.43e-148 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00149 8.23e-169 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KHGMHEMB_00150 5.34e-128 - - - I - - - PAP2 superfamily
KHGMHEMB_00151 3.22e-147 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHGMHEMB_00153 5.75e-243 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHGMHEMB_00154 3.32e-124 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHGMHEMB_00155 7.3e-22 ps301 - - K - - - sequence-specific DNA binding
KHGMHEMB_00156 1.28e-163 - - - F - - - NUDIX domain
KHGMHEMB_00157 5.55e-30 - - - G - - - Glycosyl hydrolases family 8
KHGMHEMB_00158 3.37e-46 - - - G - - - Glycosyl hydrolases family 8
KHGMHEMB_00159 3.88e-23 ykoJ - - S - - - Peptidase propeptide and YPEB domain
KHGMHEMB_00161 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHGMHEMB_00162 1.83e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KHGMHEMB_00163 5.25e-37 - - - - - - - -
KHGMHEMB_00164 3.33e-286 - - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
KHGMHEMB_00165 1.66e-135 - - - - - - - -
KHGMHEMB_00166 0.0 - - - S - - - O-antigen ligase like membrane protein
KHGMHEMB_00167 1.07e-49 - - - - - - - -
KHGMHEMB_00168 1.09e-122 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
KHGMHEMB_00169 1.37e-117 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
KHGMHEMB_00170 2.62e-36 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
KHGMHEMB_00171 2.74e-57 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
KHGMHEMB_00172 4.96e-161 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KHGMHEMB_00173 3.34e-197 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
KHGMHEMB_00175 1.3e-282 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHGMHEMB_00176 5.79e-247 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHGMHEMB_00177 3.05e-185 epsB - - M - - - biosynthesis protein
KHGMHEMB_00178 1.51e-155 ywqD - - D - - - Capsular exopolysaccharide family
KHGMHEMB_00179 3.43e-188 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KHGMHEMB_00180 2.74e-125 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KHGMHEMB_00181 6.28e-145 cps3J - - M - - - Domain of unknown function (DUF4422)
KHGMHEMB_00182 4.24e-187 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KHGMHEMB_00183 9.87e-177 - - - M - - - Glycosyl transferases group 1
KHGMHEMB_00184 8.01e-204 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KHGMHEMB_00185 1.07e-181 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
KHGMHEMB_00186 1.36e-26 - - - - - - - -
KHGMHEMB_00187 1.14e-257 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KHGMHEMB_00189 1.83e-27 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KHGMHEMB_00190 2.45e-202 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KHGMHEMB_00191 2.66e-57 - - - S - - - Enterocin A Immunity
KHGMHEMB_00192 4.11e-54 - - - S - - - Fic/DOC family
KHGMHEMB_00193 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KHGMHEMB_00194 5.35e-287 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHGMHEMB_00195 2.05e-32 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KHGMHEMB_00196 1.68e-49 sptS - - T - - - Histidine kinase
KHGMHEMB_00197 2.88e-33 dltr - - K - - - response regulator
KHGMHEMB_00198 1.45e-21 dltr - - K - - - response regulator
KHGMHEMB_00199 8.18e-15 dltr - - K - - - response regulator
KHGMHEMB_00200 3.4e-260 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_00202 1.3e-80 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
KHGMHEMB_00203 2.73e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
KHGMHEMB_00204 1.73e-116 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHGMHEMB_00205 4.7e-65 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_00206 1.14e-29 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_00207 2.23e-97 - - - - - - - -
KHGMHEMB_00208 5.72e-137 - - - K - - - LysR substrate binding domain
KHGMHEMB_00209 2.75e-27 - - - - - - - -
KHGMHEMB_00210 2.71e-281 - - - S - - - Sterol carrier protein domain
KHGMHEMB_00211 2.7e-126 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KHGMHEMB_00212 1.33e-66 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
KHGMHEMB_00213 2.85e-86 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
KHGMHEMB_00214 2e-140 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHGMHEMB_00215 4.02e-17 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHGMHEMB_00216 1.02e-38 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
KHGMHEMB_00217 2.31e-64 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
KHGMHEMB_00218 1.32e-33 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
KHGMHEMB_00219 3.44e-202 lysR5 - - K - - - LysR substrate binding domain
KHGMHEMB_00220 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
KHGMHEMB_00221 7.61e-111 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
KHGMHEMB_00222 8.81e-86 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHGMHEMB_00223 1.58e-44 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KHGMHEMB_00224 3.13e-70 sptS - - T - - - Histidine kinase
KHGMHEMB_00225 3.89e-266 - - - EGP - - - Major Facilitator Superfamily
KHGMHEMB_00226 2.64e-94 - - - O - - - OsmC-like protein
KHGMHEMB_00227 3.83e-165 - - - S - - - L-ascorbic acid biosynthetic process
KHGMHEMB_00228 2.54e-146 - - - - - - - -
KHGMHEMB_00229 8.54e-98 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
KHGMHEMB_00230 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHGMHEMB_00231 4.52e-140 vanZ - - V - - - VanZ like family
KHGMHEMB_00232 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KHGMHEMB_00233 1.99e-149 - - - EGP - - - Major Facilitator
KHGMHEMB_00234 1.02e-17 - - - EGP - - - Major Facilitator
KHGMHEMB_00235 5.14e-135 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHGMHEMB_00236 5.54e-135 - - - S - - - Uncharacterised protein family (UPF0236)
KHGMHEMB_00237 1.3e-12 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
KHGMHEMB_00242 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHGMHEMB_00243 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHGMHEMB_00244 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHGMHEMB_00245 7.84e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KHGMHEMB_00248 4.36e-104 - - - - - - - -
KHGMHEMB_00250 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KHGMHEMB_00251 5.82e-250 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHGMHEMB_00252 1.53e-211 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHGMHEMB_00253 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHGMHEMB_00254 1.26e-308 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHGMHEMB_00255 4.62e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
KHGMHEMB_00256 6.18e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KHGMHEMB_00257 1.26e-46 yabO - - J - - - S4 domain protein
KHGMHEMB_00258 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHGMHEMB_00259 6.58e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHGMHEMB_00260 2.81e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHGMHEMB_00261 2.49e-166 - - - S - - - (CBS) domain
KHGMHEMB_00262 3.96e-120 - - - K - - - transcriptional regulator
KHGMHEMB_00263 2.79e-277 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHGMHEMB_00264 6.61e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHGMHEMB_00268 1.23e-149 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KHGMHEMB_00269 0.0 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_00271 6.57e-267 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KHGMHEMB_00272 1.18e-73 - - - S - - - Acyltransferase family
KHGMHEMB_00273 4.3e-49 - - - S - - - Protein of unknown function (DUF2922)
KHGMHEMB_00274 5.99e-41 - - - - - - - -
KHGMHEMB_00275 1.04e-16 - - - - - - - -
KHGMHEMB_00277 1.63e-112 - - - - - - - -
KHGMHEMB_00278 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHGMHEMB_00279 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KHGMHEMB_00280 3.12e-291 yttB - - EGP - - - Major Facilitator
KHGMHEMB_00281 7.38e-295 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KHGMHEMB_00282 5.57e-129 yitW - - S - - - Iron-sulfur cluster assembly protein
KHGMHEMB_00283 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHGMHEMB_00284 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KHGMHEMB_00287 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
KHGMHEMB_00288 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KHGMHEMB_00289 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHGMHEMB_00290 6.05e-108 - - - - - - - -
KHGMHEMB_00291 4.61e-142 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KHGMHEMB_00292 7.76e-192 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHGMHEMB_00293 4.7e-170 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHGMHEMB_00294 6.34e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHGMHEMB_00295 1.6e-200 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
KHGMHEMB_00296 6.8e-115 usp5 - - T - - - universal stress protein
KHGMHEMB_00297 2.12e-20 - - - - - - - -
KHGMHEMB_00298 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHGMHEMB_00299 4.27e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KHGMHEMB_00300 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KHGMHEMB_00301 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHGMHEMB_00302 3.35e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KHGMHEMB_00303 2.62e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KHGMHEMB_00304 7.6e-48 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHGMHEMB_00305 1.64e-72 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHGMHEMB_00306 2.11e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHGMHEMB_00307 4.12e-47 - - - - - - - -
KHGMHEMB_00308 2.87e-101 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
KHGMHEMB_00309 2.08e-84 - - - S - - - Cupredoxin-like domain
KHGMHEMB_00310 1.81e-64 - - - S - - - Cupredoxin-like domain
KHGMHEMB_00311 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KHGMHEMB_00312 2.61e-45 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KHGMHEMB_00313 1.06e-196 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KHGMHEMB_00314 6.46e-27 - - - - - - - -
KHGMHEMB_00315 2.46e-271 - - - - - - - -
KHGMHEMB_00316 0.0 eriC - - P ko:K03281 - ko00000 chloride
KHGMHEMB_00317 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHGMHEMB_00318 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHGMHEMB_00319 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHGMHEMB_00320 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHGMHEMB_00321 1.31e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHGMHEMB_00322 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KHGMHEMB_00323 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHGMHEMB_00324 4.3e-256 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHGMHEMB_00325 2.87e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
KHGMHEMB_00326 2.55e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHGMHEMB_00327 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHGMHEMB_00328 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHGMHEMB_00329 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KHGMHEMB_00330 1.76e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHGMHEMB_00331 5.05e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHGMHEMB_00332 3.47e-13 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KHGMHEMB_00333 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KHGMHEMB_00334 1.63e-41 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KHGMHEMB_00335 6.09e-165 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KHGMHEMB_00336 1.14e-37 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KHGMHEMB_00337 1.7e-46 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KHGMHEMB_00338 9.94e-34 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KHGMHEMB_00339 5.48e-62 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KHGMHEMB_00340 4.63e-297 amd - - E - - - Peptidase family M20/M25/M40
KHGMHEMB_00341 8.21e-304 steT - - E ko:K03294 - ko00000 amino acid
KHGMHEMB_00342 4.97e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
KHGMHEMB_00343 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KHGMHEMB_00344 1.27e-111 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_00345 2.04e-48 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_00346 0.0 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
KHGMHEMB_00347 2.49e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHGMHEMB_00348 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHGMHEMB_00349 3.05e-160 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
KHGMHEMB_00350 2.86e-140 - - - L - - - Transposase and inactivated derivatives, IS30 family
KHGMHEMB_00351 4.63e-235 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
KHGMHEMB_00352 1.32e-125 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
KHGMHEMB_00353 2.44e-25 - - - - - - - -
KHGMHEMB_00354 6.93e-85 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
KHGMHEMB_00355 1.3e-44 - - - S - - - Transposase C of IS166 homeodomain
KHGMHEMB_00356 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
KHGMHEMB_00357 1.56e-190 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHGMHEMB_00358 1.51e-237 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHGMHEMB_00359 2.21e-255 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHGMHEMB_00360 1.32e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHGMHEMB_00361 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KHGMHEMB_00362 8.64e-79 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KHGMHEMB_00363 8.42e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHGMHEMB_00364 6.33e-148 - - - - - - - -
KHGMHEMB_00366 1.08e-149 - - - E - - - Belongs to the SOS response-associated peptidase family
KHGMHEMB_00367 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHGMHEMB_00368 1.09e-118 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
KHGMHEMB_00369 6.75e-140 - - - S ko:K06872 - ko00000 TPM domain
KHGMHEMB_00370 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
KHGMHEMB_00371 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHGMHEMB_00372 1.35e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KHGMHEMB_00373 3.64e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHGMHEMB_00374 7.52e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHGMHEMB_00375 2.02e-52 veg - - S - - - Biofilm formation stimulator VEG
KHGMHEMB_00376 4.49e-194 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KHGMHEMB_00377 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHGMHEMB_00378 3.08e-61 - - - S - - - SLAP domain
KHGMHEMB_00379 1.74e-96 - - - S - - - SLAP domain
KHGMHEMB_00380 6.8e-69 ykuL - - S - - - (CBS) domain
KHGMHEMB_00381 0.0 cadA - - P - - - P-type ATPase
KHGMHEMB_00382 2.59e-259 napA - - P - - - Sodium/hydrogen exchanger family
KHGMHEMB_00383 9e-66 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
KHGMHEMB_00384 1.37e-63 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
KHGMHEMB_00385 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
KHGMHEMB_00386 3.77e-114 - - - S - - - Putative adhesin
KHGMHEMB_00387 2.1e-205 mutR - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_00388 7.47e-63 - - - - - - - -
KHGMHEMB_00389 2.61e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHGMHEMB_00390 1.79e-248 - - - S - - - DUF218 domain
KHGMHEMB_00391 2.93e-16 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00392 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00393 1.47e-124 - - - S - - - ECF transporter, substrate-specific component
KHGMHEMB_00394 7.57e-207 - - - S - - - Aldo/keto reductase family
KHGMHEMB_00395 4.67e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHGMHEMB_00396 3.46e-28 - - - K - - - rpiR family
KHGMHEMB_00397 1.64e-42 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KHGMHEMB_00398 1.12e-84 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHGMHEMB_00399 0.0 mdr - - EGP - - - Major Facilitator
KHGMHEMB_00400 1.06e-279 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHGMHEMB_00403 2.49e-227 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KHGMHEMB_00406 2.72e-42 - - - K - - - Helix-turn-helix domain
KHGMHEMB_00407 5.48e-118 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHGMHEMB_00408 4.3e-277 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KHGMHEMB_00409 6.15e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KHGMHEMB_00410 1.29e-192 yycI - - S - - - YycH protein
KHGMHEMB_00411 2.41e-315 yycH - - S - - - YycH protein
KHGMHEMB_00412 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KHGMHEMB_00413 1.14e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KHGMHEMB_00415 4.46e-46 - - - - - - - -
KHGMHEMB_00417 1.2e-143 - - - - - - - -
KHGMHEMB_00418 1.05e-243 - - - S - - - Bacteriocin helveticin-J
KHGMHEMB_00419 5.5e-67 - - - - - - - -
KHGMHEMB_00420 1.2e-56 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHGMHEMB_00421 5.28e-236 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHGMHEMB_00422 3.81e-111 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KHGMHEMB_00423 8.96e-88 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KHGMHEMB_00424 7.97e-83 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00425 3.83e-47 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00426 1.22e-45 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00427 4.17e-77 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
KHGMHEMB_00428 2.51e-152 - - - K - - - Rhodanese Homology Domain
KHGMHEMB_00429 1.13e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHGMHEMB_00430 1.11e-15 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KHGMHEMB_00431 1.21e-23 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KHGMHEMB_00432 2.07e-40 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KHGMHEMB_00433 5.82e-36 - - - S - - - PD-(D/E)XK nuclease family transposase
KHGMHEMB_00434 5.48e-45 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
KHGMHEMB_00435 2.58e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KHGMHEMB_00437 1.81e-310 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KHGMHEMB_00438 1.5e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHGMHEMB_00439 9.06e-159 - - - M - - - ErfK YbiS YcfS YnhG
KHGMHEMB_00440 1.61e-102 padR - - K - - - Virulence activator alpha C-term
KHGMHEMB_00441 3.05e-98 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KHGMHEMB_00442 2.44e-148 - - - S - - - PD-(D/E)XK nuclease family transposase
KHGMHEMB_00444 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KHGMHEMB_00445 5.16e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KHGMHEMB_00446 1.46e-118 - - - L - - - NUDIX domain
KHGMHEMB_00447 3.27e-53 - - - - - - - -
KHGMHEMB_00448 2.08e-44 - - - - - - - -
KHGMHEMB_00449 9.84e-123 - - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_00450 7.9e-229 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00451 3.4e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00452 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_00453 1.16e-51 - - - - - - - -
KHGMHEMB_00454 5.2e-144 - - - K - - - WHG domain
KHGMHEMB_00455 1.81e-43 - - - S - - - Uncharacterised protein family (UPF0236)
KHGMHEMB_00457 2.34e-115 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
KHGMHEMB_00458 9.67e-250 - - - L ko:K07497 - ko00000 hmm pf00665
KHGMHEMB_00459 7.34e-55 - - - L - - - Helix-turn-helix domain
KHGMHEMB_00460 1.47e-94 - - - L - - - Helix-turn-helix domain
KHGMHEMB_00461 3.07e-206 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KHGMHEMB_00462 1.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00463 1.39e-121 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00464 1.32e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
KHGMHEMB_00465 1.79e-92 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KHGMHEMB_00466 2.03e-34 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
KHGMHEMB_00467 1.71e-99 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
KHGMHEMB_00468 2.7e-126 - 3.6.1.67 - F ko:K19965 ko00790,map00790 ko00000,ko00001,ko00002,ko01000 NUDIX domain
KHGMHEMB_00469 7.74e-257 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
KHGMHEMB_00470 9.34e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KHGMHEMB_00471 1.45e-258 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
KHGMHEMB_00472 8.76e-75 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHGMHEMB_00473 1.35e-161 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
KHGMHEMB_00474 1.42e-57 - - - - - - - -
KHGMHEMB_00475 7.65e-101 - - - K - - - LytTr DNA-binding domain
KHGMHEMB_00476 7.5e-86 - - - S - - - Protein of unknown function (DUF3021)
KHGMHEMB_00477 9.61e-102 - - - K - - - Acetyltransferase (GNAT) domain
KHGMHEMB_00478 2.21e-177 - - - - - - - -
KHGMHEMB_00479 6.28e-59 - - - - - - - -
KHGMHEMB_00480 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHGMHEMB_00481 1.4e-245 flp - - V - - - Beta-lactamase
KHGMHEMB_00482 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KHGMHEMB_00483 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KHGMHEMB_00484 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHGMHEMB_00485 7.04e-63 - - - - - - - -
KHGMHEMB_00486 1.23e-59 - - - E - - - amino acid
KHGMHEMB_00487 3.81e-59 - - - E - - - amino acid
KHGMHEMB_00488 1.26e-62 - - - - - - - -
KHGMHEMB_00489 1.38e-116 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00490 8.27e-88 - - - S - - - LPXTG cell wall anchor motif
KHGMHEMB_00491 9.14e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_00492 2.1e-135 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KHGMHEMB_00493 2.25e-49 - - - - - - - -
KHGMHEMB_00494 1.68e-84 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
KHGMHEMB_00495 2.42e-117 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KHGMHEMB_00496 8.47e-129 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KHGMHEMB_00497 4.91e-35 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KHGMHEMB_00499 7.21e-149 - - - K - - - helix_turn_helix, mercury resistance
KHGMHEMB_00500 1.36e-122 - - - K - - - Acetyltransferase (GNAT) domain
KHGMHEMB_00501 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
KHGMHEMB_00504 9.93e-108 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
KHGMHEMB_00506 3.07e-48 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00507 4.51e-18 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00508 2.02e-173 - - - S - - - YSIRK type signal peptide
KHGMHEMB_00509 4.72e-16 - - - M - - - domain protein
KHGMHEMB_00511 5.69e-70 - - - M - - - domain protein
KHGMHEMB_00513 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KHGMHEMB_00514 7.86e-306 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHGMHEMB_00515 4.1e-20 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHGMHEMB_00516 1.67e-46 - - - - - - - -
KHGMHEMB_00517 5.19e-84 - - - S ko:K07133 - ko00000 cog cog1373
KHGMHEMB_00518 6.06e-134 - - - S ko:K07133 - ko00000 cog cog1373
KHGMHEMB_00519 1.7e-131 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00520 1.52e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHGMHEMB_00521 9.19e-208 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KHGMHEMB_00522 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KHGMHEMB_00523 1.31e-70 qacA - - EGP - - - Major Facilitator
KHGMHEMB_00524 8.88e-80 qacA - - EGP - - - Major Facilitator
KHGMHEMB_00531 7.34e-22 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
KHGMHEMB_00533 2.27e-05 - - - S - - - Phage derived protein Gp49-like (DUF891)
KHGMHEMB_00534 8.86e-62 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_00535 6.23e-56 - - - - - - - -
KHGMHEMB_00536 4.07e-72 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHGMHEMB_00537 1.4e-55 - - - L - - - Probable transposase
KHGMHEMB_00538 8.84e-68 - - - L - - - Probable transposase
KHGMHEMB_00539 9.63e-51 - - - - - - - -
KHGMHEMB_00540 6.23e-63 - - - C - - - nitroreductase
KHGMHEMB_00541 0.0 yhdP - - S - - - Transporter associated domain
KHGMHEMB_00542 6.05e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHGMHEMB_00543 3.42e-297 - - - E ko:K03294 - ko00000 amino acid
KHGMHEMB_00544 4.65e-166 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00545 8.18e-269 yfmL - - L - - - DEAD DEAH box helicase
KHGMHEMB_00546 2.7e-313 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHGMHEMB_00548 2.14e-35 - - - - - - - -
KHGMHEMB_00549 1.33e-277 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHGMHEMB_00550 2.9e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
KHGMHEMB_00551 3.48e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KHGMHEMB_00552 4.23e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KHGMHEMB_00553 2.77e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KHGMHEMB_00554 5.15e-216 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHGMHEMB_00555 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHGMHEMB_00556 1.55e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHGMHEMB_00557 0.0 oatA - - I - - - Acyltransferase
KHGMHEMB_00558 1.05e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHGMHEMB_00559 1.83e-187 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KHGMHEMB_00560 6.62e-48 - - - S - - - Lipopolysaccharide assembly protein A domain
KHGMHEMB_00561 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KHGMHEMB_00562 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHGMHEMB_00563 9.47e-43 - - - S - - - Protein of unknown function (DUF2929)
KHGMHEMB_00564 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KHGMHEMB_00565 2.71e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHGMHEMB_00566 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KHGMHEMB_00567 1.08e-216 yitL - - S ko:K00243 - ko00000 S1 domain
KHGMHEMB_00568 1.48e-216 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KHGMHEMB_00569 1.62e-80 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHGMHEMB_00570 4.26e-168 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHGMHEMB_00571 8.17e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHGMHEMB_00572 1.1e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHGMHEMB_00573 1.04e-156 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHGMHEMB_00574 5.14e-58 - - - M - - - Lysin motif
KHGMHEMB_00575 1.81e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KHGMHEMB_00576 8.03e-277 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KHGMHEMB_00577 1.28e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KHGMHEMB_00578 8.21e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHGMHEMB_00579 1.1e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KHGMHEMB_00580 2.16e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHGMHEMB_00581 4.4e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHGMHEMB_00582 6.02e-151 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KHGMHEMB_00583 2.03e-191 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
KHGMHEMB_00584 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
KHGMHEMB_00585 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
KHGMHEMB_00586 4.72e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHGMHEMB_00587 5.41e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHGMHEMB_00588 8.1e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KHGMHEMB_00589 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHGMHEMB_00590 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHGMHEMB_00591 1.67e-218 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
KHGMHEMB_00592 5.68e-117 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHGMHEMB_00593 3.83e-312 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHGMHEMB_00594 4.46e-226 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KHGMHEMB_00596 3.27e-35 - - - - - - - -
KHGMHEMB_00597 1.38e-237 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHGMHEMB_00598 1.94e-149 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHGMHEMB_00599 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
KHGMHEMB_00600 3.8e-54 - - - S - - - P-loop domain protein
KHGMHEMB_00601 4.57e-27 - - - - - - - -
KHGMHEMB_00604 1.71e-108 - - - L - - - reverse transcriptase
KHGMHEMB_00605 3.32e-68 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHGMHEMB_00606 6.6e-127 - - - - - - - -
KHGMHEMB_00607 7.29e-147 - - - - - - - -
KHGMHEMB_00608 4.66e-75 - - - - - - - -
KHGMHEMB_00609 5.22e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00610 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00611 4.16e-173 - - - - - - - -
KHGMHEMB_00612 2.69e-157 - - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_00613 2.92e-232 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHGMHEMB_00614 2.76e-84 - - - - - - - -
KHGMHEMB_00615 1.2e-148 - - - GM - - - NmrA-like family
KHGMHEMB_00616 2.62e-164 - - - S - - - Alpha/beta hydrolase family
KHGMHEMB_00617 5.32e-204 epsV - - S - - - glycosyl transferase family 2
KHGMHEMB_00618 5.99e-186 - - - S - - - Protein of unknown function (DUF1002)
KHGMHEMB_00619 5.07e-188 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHGMHEMB_00620 1.97e-229 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KHGMHEMB_00621 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHGMHEMB_00622 1.14e-111 - - - - - - - -
KHGMHEMB_00623 1.45e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
KHGMHEMB_00624 1.85e-121 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
KHGMHEMB_00625 3.66e-161 terC - - P - - - Integral membrane protein TerC family
KHGMHEMB_00626 1.67e-83 yeaO - - S - - - Protein of unknown function, DUF488
KHGMHEMB_00627 1.53e-159 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KHGMHEMB_00628 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00629 6.35e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00630 8.5e-207 - - - L - - - HNH nucleases
KHGMHEMB_00631 1.3e-158 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KHGMHEMB_00632 2.88e-306 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KHGMHEMB_00633 6.67e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KHGMHEMB_00634 4.93e-221 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KHGMHEMB_00635 9.02e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KHGMHEMB_00636 1.5e-186 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHGMHEMB_00637 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHGMHEMB_00638 1.43e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KHGMHEMB_00639 5.16e-34 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KHGMHEMB_00640 6.04e-201 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KHGMHEMB_00641 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHGMHEMB_00642 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHGMHEMB_00643 2.13e-111 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
KHGMHEMB_00644 1.64e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KHGMHEMB_00645 9.21e-120 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHGMHEMB_00646 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHGMHEMB_00647 6.03e-57 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHGMHEMB_00648 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHGMHEMB_00649 3.33e-47 - - - S - - - Protein of unknown function (DUF2508)
KHGMHEMB_00650 8.42e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHGMHEMB_00651 1.52e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
KHGMHEMB_00652 4.16e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHGMHEMB_00653 1.99e-80 yabA - - L - - - Involved in initiation control of chromosome replication
KHGMHEMB_00654 8.11e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHGMHEMB_00655 9.84e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KHGMHEMB_00656 1.83e-112 - - - S - - - ECF transporter, substrate-specific component
KHGMHEMB_00657 3.97e-172 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KHGMHEMB_00658 1.95e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
KHGMHEMB_00659 9.02e-256 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHGMHEMB_00660 2.81e-06 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHGMHEMB_00661 4.99e-276 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KHGMHEMB_00662 3.69e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KHGMHEMB_00663 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KHGMHEMB_00664 1.2e-74 - - - - - - - -
KHGMHEMB_00665 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHGMHEMB_00666 5.66e-101 yutD - - S - - - Protein of unknown function (DUF1027)
KHGMHEMB_00667 1.24e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHGMHEMB_00668 1.77e-84 - - - S - - - Protein of unknown function (DUF1461)
KHGMHEMB_00669 4.16e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
KHGMHEMB_00670 2.35e-196 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KHGMHEMB_00671 3.9e-121 - - - - - - - -
KHGMHEMB_00672 1.93e-30 - - - - - - - -
KHGMHEMB_00673 2.47e-132 - - - - - - - -
KHGMHEMB_00674 9.73e-226 degV1 - - S - - - DegV family
KHGMHEMB_00675 4.24e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KHGMHEMB_00676 0.000255 - - - S - - - CsbD-like
KHGMHEMB_00677 5.32e-35 - - - S - - - Transglycosylase associated protein
KHGMHEMB_00678 1.16e-304 - - - I - - - Protein of unknown function (DUF2974)
KHGMHEMB_00679 3.78e-156 - - - S ko:K07507 - ko00000,ko02000 MgtC family
KHGMHEMB_00682 5.36e-65 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00684 1.79e-12 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHGMHEMB_00685 1.04e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHGMHEMB_00687 2.34e-221 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KHGMHEMB_00688 4.3e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHGMHEMB_00689 6.64e-233 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KHGMHEMB_00690 3.16e-259 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
KHGMHEMB_00693 2.34e-233 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHGMHEMB_00694 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHGMHEMB_00695 1.75e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHGMHEMB_00696 7.09e-76 - - - - - - - -
KHGMHEMB_00697 1.18e-113 - - - - - - - -
KHGMHEMB_00698 2.58e-94 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
KHGMHEMB_00699 1.12e-88 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
KHGMHEMB_00700 3.02e-225 - - - S - - - DUF218 domain
KHGMHEMB_00701 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KHGMHEMB_00702 2.35e-106 - - - C - - - Flavodoxin
KHGMHEMB_00703 5.7e-146 - - - I - - - Acid phosphatase homologues
KHGMHEMB_00704 2.43e-144 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KHGMHEMB_00705 1.3e-265 - - - V - - - Beta-lactamase
KHGMHEMB_00706 7.49e-196 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KHGMHEMB_00707 1.73e-121 - - - S - - - ECF-type riboflavin transporter, S component
KHGMHEMB_00708 6.81e-293 - - - S - - - Putative peptidoglycan binding domain
KHGMHEMB_00709 3.46e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
KHGMHEMB_00710 0.0 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KHGMHEMB_00711 7.96e-45 - - - - - - - -
KHGMHEMB_00712 4.31e-40 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KHGMHEMB_00713 4.01e-80 - - - - - - - -
KHGMHEMB_00714 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
KHGMHEMB_00715 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_00716 1.18e-126 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KHGMHEMB_00717 2.15e-86 - - - - - - - -
KHGMHEMB_00718 1.53e-81 - - - S - - - Fic/DOC family
KHGMHEMB_00719 1.17e-132 - - - - - - - -
KHGMHEMB_00720 4.04e-265 - - - EGP - - - Major Facilitator Superfamily
KHGMHEMB_00721 1.22e-89 yslB - - S - - - Protein of unknown function (DUF2507)
KHGMHEMB_00722 2.92e-190 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KHGMHEMB_00723 1.85e-149 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHGMHEMB_00724 2.49e-72 - - - - - - - -
KHGMHEMB_00725 1.34e-278 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
KHGMHEMB_00726 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHGMHEMB_00727 1.17e-30 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_00728 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_00729 4.38e-152 - - - Q - - - Imidazolonepropionase and related amidohydrolases
KHGMHEMB_00730 1.04e-135 - - - Q - - - Imidazolonepropionase and related amidohydrolases
KHGMHEMB_00731 9.23e-305 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHGMHEMB_00732 5.54e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
KHGMHEMB_00733 9.85e-154 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHGMHEMB_00734 7.77e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KHGMHEMB_00735 2.66e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
KHGMHEMB_00736 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
KHGMHEMB_00737 1.08e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KHGMHEMB_00738 6.96e-180 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
KHGMHEMB_00739 1.51e-176 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHGMHEMB_00740 3.82e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KHGMHEMB_00741 2.75e-165 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_00742 4.47e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00743 1.98e-45 - - - - - - - -
KHGMHEMB_00744 1.73e-24 - - - - - - - -
KHGMHEMB_00745 1.67e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
KHGMHEMB_00746 3.61e-225 ydbI - - K - - - AI-2E family transporter
KHGMHEMB_00747 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
KHGMHEMB_00748 8.81e-89 - - - S - - - Domain of unknown function (DUF4430)
KHGMHEMB_00749 1.56e-114 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
KHGMHEMB_00750 1.09e-129 - - - S - - - Cob(I)alamin adenosyltransferase
KHGMHEMB_00751 9.87e-193 - - - S - - - Putative ABC-transporter type IV
KHGMHEMB_00752 1.69e-312 - - - S - - - LPXTG cell wall anchor motif
KHGMHEMB_00753 8.83e-43 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_00755 8.64e-56 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHGMHEMB_00756 5.7e-72 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_00757 1.1e-102 - - - E - - - Zn peptidase
KHGMHEMB_00758 1.18e-149 - - - - - - - -
KHGMHEMB_00759 6.17e-189 - - - I - - - Acyl-transferase
KHGMHEMB_00760 2.53e-151 - - - - - - - -
KHGMHEMB_00761 1.5e-295 - - - L - - - COG3547 Transposase and inactivated derivatives
KHGMHEMB_00762 1.2e-147 - - - K - - - Helix-turn-helix domain
KHGMHEMB_00763 4.51e-13 - - - K - - - Helix-turn-helix domain
KHGMHEMB_00764 1.04e-83 arbx - - M - - - Glycosyl transferase family 8
KHGMHEMB_00765 3.17e-68 arbx - - M - - - Glycosyl transferase family 8
KHGMHEMB_00766 2.82e-234 - - - M - - - Glycosyl transferase family 8
KHGMHEMB_00767 1.06e-207 - - - M - - - Glycosyl transferase family 8
KHGMHEMB_00768 1.87e-213 arbZ - - I - - - Phosphate acyltransferases
KHGMHEMB_00769 5.04e-47 - - - S - - - Cytochrome b5
KHGMHEMB_00770 4.64e-143 - - - K - - - Transcriptional regulator, LysR family
KHGMHEMB_00771 1.01e-09 - - - K - - - LysR substrate binding domain
KHGMHEMB_00772 1.14e-79 - - - K - - - LysR substrate binding domain
KHGMHEMB_00773 2.32e-51 - - - K - - - LysR substrate binding domain
KHGMHEMB_00774 6.25e-132 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KHGMHEMB_00775 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
KHGMHEMB_00776 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00777 5.88e-311 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KHGMHEMB_00778 4.8e-80 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KHGMHEMB_00779 6.26e-14 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KHGMHEMB_00780 3.81e-82 - - - K - - - Transcriptional regulator
KHGMHEMB_00781 3.83e-83 - - - K - - - Transcriptional regulator
KHGMHEMB_00782 1.6e-82 - - - S - - - Domain of unknown function (DUF956)
KHGMHEMB_00783 7.39e-224 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
KHGMHEMB_00784 5.16e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
KHGMHEMB_00785 2.96e-242 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KHGMHEMB_00786 1.84e-20 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KHGMHEMB_00787 8.71e-278 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KHGMHEMB_00788 8.85e-47 - - - S - - - Protein of unknown function (DUF2969)
KHGMHEMB_00789 1.31e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KHGMHEMB_00790 7.12e-229 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KHGMHEMB_00791 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
KHGMHEMB_00792 2.98e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KHGMHEMB_00793 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHGMHEMB_00794 6.03e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHGMHEMB_00795 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHGMHEMB_00796 4.8e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHGMHEMB_00797 1.15e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHGMHEMB_00798 2.16e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHGMHEMB_00799 2.91e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KHGMHEMB_00800 8.75e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHGMHEMB_00801 6.48e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHGMHEMB_00802 2.07e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHGMHEMB_00803 5.18e-234 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHGMHEMB_00804 1.21e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KHGMHEMB_00805 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
KHGMHEMB_00806 8.08e-160 - - - L - - - Belongs to the 'phage' integrase family
KHGMHEMB_00807 3.3e-51 - - - - - - - -
KHGMHEMB_00808 1.49e-186 - - - - - - - -
KHGMHEMB_00809 3.51e-189 - - - - - - - -
KHGMHEMB_00810 1.81e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHGMHEMB_00811 7.06e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
KHGMHEMB_00812 2.1e-309 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KHGMHEMB_00813 5.96e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHGMHEMB_00814 2.22e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KHGMHEMB_00815 1.09e-39 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KHGMHEMB_00816 7.41e-145 - - - S - - - Peptidase family M23
KHGMHEMB_00817 4.3e-195 - - - - - - - -
KHGMHEMB_00818 9.69e-25 - - - - - - - -
KHGMHEMB_00819 5.56e-21 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
KHGMHEMB_00820 1.36e-91 - - - S - - - Iron-sulphur cluster biosynthesis
KHGMHEMB_00821 1.94e-248 ysdE - - P - - - Citrate transporter
KHGMHEMB_00822 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
KHGMHEMB_00823 1.92e-206 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KHGMHEMB_00824 6.02e-85 - - - L - - - Helix-turn-helix domain
KHGMHEMB_00825 1.25e-10 - - - L ko:K07497 - ko00000 hmm pf00665
KHGMHEMB_00826 4.39e-75 - - - L ko:K07497 - ko00000 hmm pf00665
KHGMHEMB_00827 8.6e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
KHGMHEMB_00828 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_00829 6.62e-128 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KHGMHEMB_00830 4.28e-226 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KHGMHEMB_00831 5.71e-262 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
KHGMHEMB_00832 3.06e-205 - - - S - - - EDD domain protein, DegV family
KHGMHEMB_00833 5.69e-86 - - - - - - - -
KHGMHEMB_00834 0.0 FbpA - - K - - - Fibronectin-binding protein
KHGMHEMB_00835 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KHGMHEMB_00836 5.87e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KHGMHEMB_00837 5.38e-220 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHGMHEMB_00838 7.77e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHGMHEMB_00839 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KHGMHEMB_00840 8.11e-44 - - - - - - - -
KHGMHEMB_00841 1.77e-101 cpdA - - S - - - Calcineurin-like phosphoesterase
KHGMHEMB_00842 1.29e-108 cpdA - - S - - - Calcineurin-like phosphoesterase
KHGMHEMB_00843 5.39e-14 cpdA - - S - - - Calcineurin-like phosphoesterase
KHGMHEMB_00844 3.54e-279 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KHGMHEMB_00845 2.24e-92 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHGMHEMB_00846 9.69e-139 ypsA - - S - - - Belongs to the UPF0398 family
KHGMHEMB_00847 9.14e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHGMHEMB_00848 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KHGMHEMB_00849 1.46e-146 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHGMHEMB_00850 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
KHGMHEMB_00851 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KHGMHEMB_00852 6.04e-117 ypmB - - S - - - Protein conserved in bacteria
KHGMHEMB_00853 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KHGMHEMB_00854 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KHGMHEMB_00855 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHGMHEMB_00856 6.51e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
KHGMHEMB_00857 1.06e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KHGMHEMB_00858 4.69e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KHGMHEMB_00859 1.3e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHGMHEMB_00860 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
KHGMHEMB_00861 1.5e-229 - - - - - - - -
KHGMHEMB_00862 3.69e-180 - - - - - - - -
KHGMHEMB_00863 1.54e-135 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Peptidase S24-like
KHGMHEMB_00864 7.83e-38 - - - - - - - -
KHGMHEMB_00865 7.32e-77 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KHGMHEMB_00866 4.14e-51 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KHGMHEMB_00867 6.04e-41 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KHGMHEMB_00868 1.15e-90 - - - - - - - -
KHGMHEMB_00869 9.14e-50 - - - - - - - -
KHGMHEMB_00871 1.83e-194 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KHGMHEMB_00872 1.9e-65 - - - - - - - -
KHGMHEMB_00873 5.88e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KHGMHEMB_00874 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHGMHEMB_00875 7.06e-30 - - - - - - - -
KHGMHEMB_00876 2.21e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KHGMHEMB_00877 4.47e-230 lipA - - I - - - Carboxylesterase family
KHGMHEMB_00879 1.44e-276 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_00880 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KHGMHEMB_00881 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KHGMHEMB_00882 2.83e-167 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KHGMHEMB_00883 2.68e-33 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KHGMHEMB_00884 9.05e-190 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KHGMHEMB_00885 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
KHGMHEMB_00886 3.38e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KHGMHEMB_00887 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KHGMHEMB_00888 2.43e-263 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KHGMHEMB_00889 1.04e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHGMHEMB_00890 3.98e-92 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KHGMHEMB_00891 1.28e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHGMHEMB_00892 1.4e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHGMHEMB_00893 5.54e-247 - - - S - - - Domain of unknown function (DUF389)
KHGMHEMB_00894 3.62e-36 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KHGMHEMB_00895 7.84e-298 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KHGMHEMB_00896 1.44e-74 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHGMHEMB_00897 4.77e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KHGMHEMB_00898 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHGMHEMB_00899 1.51e-121 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KHGMHEMB_00900 1.22e-272 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KHGMHEMB_00901 4.02e-159 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHGMHEMB_00902 9.61e-141 yqeK - - H - - - Hydrolase, HD family
KHGMHEMB_00903 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHGMHEMB_00904 1.89e-274 ylbM - - S - - - Belongs to the UPF0348 family
KHGMHEMB_00905 5.19e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KHGMHEMB_00906 2.12e-164 csrR - - K - - - response regulator
KHGMHEMB_00907 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KHGMHEMB_00908 1.67e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KHGMHEMB_00909 3e-205 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHGMHEMB_00910 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KHGMHEMB_00911 6.34e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHGMHEMB_00912 2.06e-82 yodB - - K - - - Transcriptional regulator, HxlR family
KHGMHEMB_00913 5.46e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHGMHEMB_00914 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHGMHEMB_00915 2.74e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHGMHEMB_00916 9.25e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
KHGMHEMB_00917 1.79e-77 - - - S - - - Phage derived protein Gp49-like (DUF891)
KHGMHEMB_00918 5.83e-52 - - - K - - - Helix-turn-helix domain
KHGMHEMB_00919 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KHGMHEMB_00920 1.07e-59 - - - L - - - Psort location Cytoplasmic, score
KHGMHEMB_00921 1.2e-193 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHGMHEMB_00922 7.53e-203 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHGMHEMB_00923 5.11e-171 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KHGMHEMB_00924 1.01e-125 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
KHGMHEMB_00925 1.57e-91 - - - L - - - Transposase and inactivated derivatives, IS30 family
KHGMHEMB_00933 1.19e-279 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
KHGMHEMB_00934 7.74e-258 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KHGMHEMB_00935 1.94e-226 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHGMHEMB_00936 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHGMHEMB_00937 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KHGMHEMB_00938 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHGMHEMB_00939 4.52e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHGMHEMB_00941 1.56e-231 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHGMHEMB_00942 1.74e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHGMHEMB_00943 1.13e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHGMHEMB_00945 6.71e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
KHGMHEMB_00946 9.97e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHGMHEMB_00947 6.01e-288 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KHGMHEMB_00948 1.34e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHGMHEMB_00949 4.35e-125 - - - - - - - -
KHGMHEMB_00950 1.52e-205 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHGMHEMB_00951 2.33e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHGMHEMB_00952 3.84e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KHGMHEMB_00953 1.87e-118 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KHGMHEMB_00954 1.06e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHGMHEMB_00955 1.47e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KHGMHEMB_00956 4.51e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHGMHEMB_00957 3.06e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00958 3.23e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_00959 1.71e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_00960 8.69e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHGMHEMB_00961 5.29e-218 ybbR - - S - - - YbbR-like protein
KHGMHEMB_00962 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHGMHEMB_00963 1.76e-193 - - - S - - - hydrolase
KHGMHEMB_00964 7.18e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHGMHEMB_00965 8.67e-43 - - - - - - - -
KHGMHEMB_00966 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KHGMHEMB_00967 4.1e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHGMHEMB_00968 6.88e-279 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHGMHEMB_00969 7.17e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KHGMHEMB_00970 1.01e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHGMHEMB_00971 4.51e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHGMHEMB_00972 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHGMHEMB_00973 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHGMHEMB_00974 4.12e-254 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KHGMHEMB_00975 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KHGMHEMB_00976 2.66e-310 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KHGMHEMB_00977 2.65e-97 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_00978 5.59e-251 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHGMHEMB_00979 7.59e-48 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHGMHEMB_00980 6.71e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHGMHEMB_00981 8.78e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KHGMHEMB_00982 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KHGMHEMB_00983 3.93e-28 - - - S - - - ASCH
KHGMHEMB_00984 6.84e-57 - - - S - - - ASCH
KHGMHEMB_00985 7.26e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KHGMHEMB_00986 1.67e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHGMHEMB_00987 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHGMHEMB_00988 9.69e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHGMHEMB_00989 4.49e-315 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHGMHEMB_00990 8.11e-190 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KHGMHEMB_00991 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KHGMHEMB_00992 1.59e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHGMHEMB_00993 2.51e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KHGMHEMB_00994 8.07e-164 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KHGMHEMB_00995 1.06e-68 - - - - - - - -
KHGMHEMB_00996 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KHGMHEMB_00997 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
KHGMHEMB_00998 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KHGMHEMB_00999 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHGMHEMB_01000 3.85e-235 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHGMHEMB_01001 5.34e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHGMHEMB_01002 6.3e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHGMHEMB_01003 3.56e-233 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHGMHEMB_01004 7.39e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_01005 8.29e-202 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHGMHEMB_01006 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHGMHEMB_01007 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHGMHEMB_01008 8.32e-37 - - - S - - - Uncharacterised protein, DegV family COG1307
KHGMHEMB_01009 5.94e-119 - - - S - - - Uncharacterised protein, DegV family COG1307
KHGMHEMB_01010 6.08e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHGMHEMB_01011 1.7e-102 - - - S - - - Domain of unknown function (DUF4767)
KHGMHEMB_01012 2.03e-111 yfhC - - C - - - nitroreductase
KHGMHEMB_01013 5.95e-14 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHGMHEMB_01014 4.37e-102 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHGMHEMB_01015 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01016 1.7e-171 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHGMHEMB_01017 7.36e-240 - - - S - - - SLAP domain
KHGMHEMB_01019 2.94e-50 - - - - - - - -
KHGMHEMB_01020 2.64e-268 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHGMHEMB_01021 1.65e-267 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
KHGMHEMB_01022 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KHGMHEMB_01023 4.5e-151 - - - K - - - Protein of unknown function (DUF4065)
KHGMHEMB_01024 1.14e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHGMHEMB_01025 4.31e-152 - - - - - - - -
KHGMHEMB_01026 7.36e-251 ampC - - V - - - Beta-lactamase
KHGMHEMB_01029 2.19e-84 - - - - - - - -
KHGMHEMB_01031 0.0 - - - S ko:K06919 - ko00000 Virulence-associated protein E
KHGMHEMB_01033 1.72e-58 - - - - - - - -
KHGMHEMB_01034 1.47e-45 - - - - - - - -
KHGMHEMB_01035 5.04e-47 - - - - - - - -
KHGMHEMB_01036 3.1e-51 - - - - - - - -
KHGMHEMB_01037 3.7e-128 - - - K - - - Transcriptional
KHGMHEMB_01038 5.7e-115 - - - L - - - Belongs to the 'phage' integrase family
KHGMHEMB_01039 1.76e-127 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KHGMHEMB_01040 4.46e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KHGMHEMB_01041 7.79e-193 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHGMHEMB_01042 7.75e-232 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHGMHEMB_01043 1.28e-115 cvpA - - S - - - Colicin V production protein
KHGMHEMB_01044 6.6e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KHGMHEMB_01045 3.28e-193 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHGMHEMB_01046 1.43e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KHGMHEMB_01047 1.96e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHGMHEMB_01048 6.38e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KHGMHEMB_01049 4.85e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHGMHEMB_01050 9.33e-179 - - - S - - - Protein of unknown function (DUF1129)
KHGMHEMB_01051 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_01052 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KHGMHEMB_01053 2.9e-157 vanR - - K - - - response regulator
KHGMHEMB_01054 3.1e-268 - - - T - - - His Kinase A (phosphoacceptor) domain
KHGMHEMB_01055 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHGMHEMB_01056 6.67e-187 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KHGMHEMB_01057 2.43e-143 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
KHGMHEMB_01058 2.99e-19 - - - S - - - Enterocin A Immunity
KHGMHEMB_01059 9.59e-69 - - - S - - - Enterocin A Immunity
KHGMHEMB_01060 7.29e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KHGMHEMB_01061 8.68e-44 - - - - - - - -
KHGMHEMB_01062 5.7e-36 - - - - - - - -
KHGMHEMB_01065 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHGMHEMB_01066 5.33e-304 - - - M - - - Glycosyltransferase like family 2
KHGMHEMB_01068 2.33e-264 - - - EGP - - - Transmembrane secretion effector
KHGMHEMB_01069 2.53e-134 tnpR1 - - L - - - Resolvase, N terminal domain
KHGMHEMB_01070 2.04e-103 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHGMHEMB_01071 7.51e-96 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHGMHEMB_01072 1.28e-107 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHGMHEMB_01073 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KHGMHEMB_01074 2.41e-45 - - - - - - - -
KHGMHEMB_01075 7.38e-121 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KHGMHEMB_01076 6.12e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHGMHEMB_01077 2.1e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHGMHEMB_01078 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHGMHEMB_01079 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHGMHEMB_01080 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHGMHEMB_01081 7.71e-133 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KHGMHEMB_01082 5.04e-71 - - - - - - - -
KHGMHEMB_01083 3.55e-81 - - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_01084 4.23e-141 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_01085 1.77e-66 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_01086 1.73e-41 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_01087 2.55e-214 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
KHGMHEMB_01088 1.3e-121 - - - K - - - acetyltransferase
KHGMHEMB_01089 1.7e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KHGMHEMB_01090 2.8e-201 snf - - KL - - - domain protein
KHGMHEMB_01091 1.57e-136 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHGMHEMB_01092 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHGMHEMB_01093 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHGMHEMB_01094 7.3e-219 - - - K - - - Transcriptional regulator
KHGMHEMB_01095 7.36e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KHGMHEMB_01096 4.04e-25 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHGMHEMB_01097 1.05e-94 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHGMHEMB_01098 3.16e-73 - - - K - - - Helix-turn-helix domain
KHGMHEMB_01099 1.12e-73 - - - S - - - Protein of unknown function (DUF1275)
KHGMHEMB_01100 2.15e-48 - - - S - - - Transglycosylase associated protein
KHGMHEMB_01101 3.07e-32 - - - - - - - -
KHGMHEMB_01102 1.28e-68 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
KHGMHEMB_01103 7.94e-176 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
KHGMHEMB_01104 1.2e-87 - - - S - - - GtrA-like protein
KHGMHEMB_01105 5.59e-220 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
KHGMHEMB_01106 2.29e-310 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KHGMHEMB_01107 8.55e-47 - - - - ko:K19167 - ko00000,ko02048 -
KHGMHEMB_01108 0.0 - - - S - - - Protein of unknown function DUF262
KHGMHEMB_01109 4e-205 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHGMHEMB_01110 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KHGMHEMB_01111 8.09e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHGMHEMB_01112 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHGMHEMB_01113 2.17e-265 - - - M - - - Glycosyl transferases group 1
KHGMHEMB_01114 2.05e-173 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHGMHEMB_01115 4.6e-170 - - - - - - - -
KHGMHEMB_01116 1.57e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHGMHEMB_01117 2.97e-143 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHGMHEMB_01118 8.95e-129 - - - G - - - Aldose 1-epimerase
KHGMHEMB_01119 5.03e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHGMHEMB_01120 3.19e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHGMHEMB_01121 0.0 XK27_08315 - - M - - - Sulfatase
KHGMHEMB_01122 0.0 - - - S - - - Fibronectin type III domain
KHGMHEMB_01123 8.92e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHGMHEMB_01124 2.3e-71 - - - - - - - -
KHGMHEMB_01126 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KHGMHEMB_01127 1.07e-158 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHGMHEMB_01128 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KHGMHEMB_01129 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KHGMHEMB_01130 7.59e-268 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHGMHEMB_01131 1.57e-37 - - - - - - - -
KHGMHEMB_01132 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHGMHEMB_01133 2.91e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_01134 1.75e-276 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHGMHEMB_01135 4.76e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KHGMHEMB_01136 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
KHGMHEMB_01137 3.58e-155 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KHGMHEMB_01138 8.44e-163 - - - - - - - -
KHGMHEMB_01139 1.95e-307 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KHGMHEMB_01140 1.76e-312 yifK - - E ko:K03293 - ko00000 Amino acid permease
KHGMHEMB_01141 6.66e-71 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_01142 4.32e-100 - - - E - - - Zn peptidase
KHGMHEMB_01143 1.01e-267 - - - S - - - SLAP domain
KHGMHEMB_01144 8.56e-248 - - - S - - - Bacteriocin helveticin-J
KHGMHEMB_01145 5.16e-66 - - - - - - - -
KHGMHEMB_01146 2.89e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHGMHEMB_01147 1.26e-91 yqhL - - P - - - Rhodanese-like protein
KHGMHEMB_01148 2.45e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KHGMHEMB_01149 2.29e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
KHGMHEMB_01150 3.12e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHGMHEMB_01151 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KHGMHEMB_01152 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KHGMHEMB_01153 0.0 - - - S - - - membrane
KHGMHEMB_01154 1.22e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
KHGMHEMB_01155 1.89e-276 - - - S - - - Membrane
KHGMHEMB_01156 9.91e-68 - - - - - - - -
KHGMHEMB_01157 6.46e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
KHGMHEMB_01158 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHGMHEMB_01159 4.08e-311 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KHGMHEMB_01160 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHGMHEMB_01161 9.71e-317 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHGMHEMB_01162 1.38e-223 pbpX2 - - V - - - Beta-lactamase
KHGMHEMB_01165 2.29e-162 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHGMHEMB_01166 1.01e-23 - - - - - - - -
KHGMHEMB_01167 3.35e-64 - - - - - - - -
KHGMHEMB_01168 2.32e-161 - - - S - - - Protein of unknown function (DUF975)
KHGMHEMB_01169 1.88e-186 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHGMHEMB_01170 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KHGMHEMB_01171 8.11e-56 - - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_01173 2.6e-44 - - - S - - - Domain of unknown function (DUF4440)
KHGMHEMB_01174 4.57e-171 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KHGMHEMB_01175 9.52e-135 - - - C - - - Aldo keto reductase
KHGMHEMB_01176 8.1e-104 - - - GM - - - NAD(P)H-binding
KHGMHEMB_01178 7.09e-48 - - - G - - - MFS/sugar transport protein
KHGMHEMB_01179 8.86e-29 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KHGMHEMB_01180 2.64e-243 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KHGMHEMB_01181 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
KHGMHEMB_01182 3.88e-241 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
KHGMHEMB_01183 6.23e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KHGMHEMB_01184 1.3e-273 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KHGMHEMB_01185 6.11e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KHGMHEMB_01186 2.8e-277 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KHGMHEMB_01187 2.81e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KHGMHEMB_01188 1.62e-62 - - - - - - - -
KHGMHEMB_01189 4.88e-21 ybcH - - D ko:K06889 - ko00000 Alpha beta
KHGMHEMB_01190 1.63e-187 - - - S - - - Peptidase_C39 like family
KHGMHEMB_01191 8.95e-110 - - - S - - - Threonine/Serine exporter, ThrE
KHGMHEMB_01192 5.87e-180 - - - S - - - Putative threonine/serine exporter
KHGMHEMB_01193 0.0 - - - S - - - ABC transporter
KHGMHEMB_01194 2.34e-74 - - - - - - - -
KHGMHEMB_01195 1.44e-133 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHGMHEMB_01196 4.75e-78 - - - L - - - PFAM transposase, IS4 family protein
KHGMHEMB_01197 5.93e-51 - - - L - - - PFAM transposase, IS4 family protein
KHGMHEMB_01198 4.52e-62 - - - L - - - PFAM transposase, IS4 family protein
KHGMHEMB_01199 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHGMHEMB_01202 5.49e-22 - - - C - - - nitroreductase
KHGMHEMB_01204 2.69e-84 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
KHGMHEMB_01206 5.2e-188 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHGMHEMB_01207 2.02e-117 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
KHGMHEMB_01208 1.4e-20 - - - L - - - Integrase
KHGMHEMB_01209 0.000549 - - - - - - - -
KHGMHEMB_01210 1.02e-27 - - - - - - - -
KHGMHEMB_01211 1.94e-29 - - - - - - - -
KHGMHEMB_01212 4.41e-14 - - - - - - - -
KHGMHEMB_01213 1.33e-38 - - - - - - - -
KHGMHEMB_01214 2.21e-15 - - - - - - - -
KHGMHEMB_01215 8.6e-90 yngC - - S - - - SNARE associated Golgi protein
KHGMHEMB_01216 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
KHGMHEMB_01217 4.95e-57 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHGMHEMB_01218 6.24e-98 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHGMHEMB_01219 9.09e-20 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHGMHEMB_01220 2.07e-58 yxeH - - S - - - hydrolase
KHGMHEMB_01221 2.13e-108 yxeH - - S - - - hydrolase
KHGMHEMB_01222 7.53e-203 - - - S - - - reductase
KHGMHEMB_01223 6.4e-280 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHGMHEMB_01224 9.05e-222 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_01226 4.79e-31 - - - - - - - -
KHGMHEMB_01227 0.0 yclK - - T - - - Histidine kinase
KHGMHEMB_01228 9.37e-169 - - - K - - - Transcriptional regulatory protein, C terminal
KHGMHEMB_01229 3.18e-79 - - - S - - - SdpI/YhfL protein family
KHGMHEMB_01230 5.58e-222 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KHGMHEMB_01231 1.06e-88 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KHGMHEMB_01232 2.26e-163 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KHGMHEMB_01233 4.66e-46 - - - M - - - Protein of unknown function (DUF3737)
KHGMHEMB_01234 1.32e-50 - - - M - - - Protein of unknown function (DUF3737)
KHGMHEMB_01236 1.16e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_01237 2.53e-240 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KHGMHEMB_01238 2.17e-108 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KHGMHEMB_01239 1.18e-55 - - - - - - - -
KHGMHEMB_01240 2.04e-95 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
KHGMHEMB_01241 6.15e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
KHGMHEMB_01242 5.29e-193 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KHGMHEMB_01243 8.35e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
KHGMHEMB_01244 3.98e-171 yebC - - K - - - Transcriptional regulatory protein
KHGMHEMB_01245 5.73e-120 - - - S - - - VanZ like family
KHGMHEMB_01246 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHGMHEMB_01247 7.9e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KHGMHEMB_01248 3.17e-164 - - - S - - - Haloacid dehalogenase-like hydrolase
KHGMHEMB_01249 3.32e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
KHGMHEMB_01250 2.12e-228 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KHGMHEMB_01251 4.28e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KHGMHEMB_01252 2.4e-125 mreD - - - ko:K03571 - ko00000,ko03036 -
KHGMHEMB_01253 1.09e-18 - - - S - - - Protein of unknown function (DUF4044)
KHGMHEMB_01254 4.46e-72 - - - S - - - Protein of unknown function (DUF3397)
KHGMHEMB_01255 8.18e-55 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
KHGMHEMB_01257 9.42e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHGMHEMB_01258 2.22e-30 - - - - - - - -
KHGMHEMB_01259 2.44e-100 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KHGMHEMB_01260 5.16e-50 - - - - - - - -
KHGMHEMB_01261 2.19e-69 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KHGMHEMB_01262 3.34e-115 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KHGMHEMB_01263 3.62e-55 - - - - - - - -
KHGMHEMB_01264 2.99e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHGMHEMB_01265 1.98e-88 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHGMHEMB_01266 1.02e-242 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_01267 1.07e-137 - - - L - - - Resolvase, N terminal domain
KHGMHEMB_01268 3.44e-57 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_01269 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KHGMHEMB_01270 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KHGMHEMB_01271 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KHGMHEMB_01272 2.38e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KHGMHEMB_01273 1.21e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHGMHEMB_01274 7.81e-282 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHGMHEMB_01275 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHGMHEMB_01276 1.98e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_01277 0.0 - - - M - - - domain, Protein
KHGMHEMB_01278 1.71e-81 - 3.2.1.4 GH5,GH9 M ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 domain protein
KHGMHEMB_01279 4.21e-30 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
KHGMHEMB_01280 3.69e-30 - - - K - - - DeoR C terminal sensor domain
KHGMHEMB_01281 1.12e-122 - - - - - - - -
KHGMHEMB_01282 1.83e-33 - - - S - - - Small integral membrane protein (DUF2273)
KHGMHEMB_01283 7.06e-114 asp1 - - S - - - Asp23 family, cell envelope-related function
KHGMHEMB_01284 3.42e-41 - - - S - - - Transglycosylase associated protein
KHGMHEMB_01285 1.14e-23 - - - - - - - -
KHGMHEMB_01286 3.8e-93 - - - S - - - Peptidase family M23
KHGMHEMB_01287 5.7e-198 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHGMHEMB_01288 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KHGMHEMB_01289 1.26e-91 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KHGMHEMB_01290 6.07e-225 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KHGMHEMB_01291 2.62e-131 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHGMHEMB_01292 6.28e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHGMHEMB_01293 8.01e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KHGMHEMB_01294 2.22e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KHGMHEMB_01295 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KHGMHEMB_01296 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHGMHEMB_01297 3.14e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHGMHEMB_01299 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KHGMHEMB_01302 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_01303 2.79e-297 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHGMHEMB_01304 4.86e-35 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KHGMHEMB_01305 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KHGMHEMB_01306 1.76e-85 - - - S - - - SLAP domain
KHGMHEMB_01307 9.68e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KHGMHEMB_01308 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KHGMHEMB_01309 1.99e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHGMHEMB_01311 5.09e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHGMHEMB_01312 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KHGMHEMB_01313 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHGMHEMB_01314 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHGMHEMB_01315 3.98e-132 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
KHGMHEMB_01316 9.36e-208 XK27_02480 - - EGP - - - Major facilitator Superfamily
KHGMHEMB_01317 3.73e-235 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHGMHEMB_01319 2.14e-53 - - - L - - - Psort location Cytoplasmic, score
KHGMHEMB_01320 4.11e-171 - - - L - - - Psort location Cytoplasmic, score
KHGMHEMB_01321 2.95e-110 - - - FG - - - adenosine 5'-monophosphoramidase activity
KHGMHEMB_01322 1.03e-61 - - - - - - - -
KHGMHEMB_01323 1.98e-133 - - - L - - - Integrase
KHGMHEMB_01324 2.09e-55 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
KHGMHEMB_01325 4.68e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KHGMHEMB_01326 1.43e-221 ydhF - - S - - - Aldo keto reductase
KHGMHEMB_01327 1.68e-226 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
KHGMHEMB_01328 1.1e-108 - - - - - - - -
KHGMHEMB_01329 5.67e-24 - - - C - - - FMN_bind
KHGMHEMB_01330 0.0 - - - I - - - Protein of unknown function (DUF2974)
KHGMHEMB_01331 7.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHGMHEMB_01332 9.93e-266 pbpX1 - - V - - - Beta-lactamase
KHGMHEMB_01334 2.24e-74 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01335 3.02e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHGMHEMB_01336 7.71e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHGMHEMB_01337 5.2e-132 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KHGMHEMB_01338 8.53e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHGMHEMB_01339 1.35e-116 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KHGMHEMB_01340 9.32e-293 - - - G - - - Antibiotic biosynthesis monooxygenase
KHGMHEMB_01341 3.94e-144 - - - G - - - Phosphoglycerate mutase family
KHGMHEMB_01342 3.94e-249 - - - D - - - nuclear chromosome segregation
KHGMHEMB_01343 7.27e-132 - - - M - - - LysM domain protein
KHGMHEMB_01344 5.26e-19 - - - - - - - -
KHGMHEMB_01345 1.01e-27 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
KHGMHEMB_01346 1.02e-61 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
KHGMHEMB_01347 2.07e-37 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
KHGMHEMB_01348 1.61e-88 - - - - - - - -
KHGMHEMB_01349 1.52e-43 - - - - - - - -
KHGMHEMB_01350 4.09e-92 - - - S - - - Iron-sulphur cluster biosynthesis
KHGMHEMB_01351 1.21e-126 yibF - - S - - - overlaps another CDS with the same product name
KHGMHEMB_01352 2.4e-258 yibE - - S - - - overlaps another CDS with the same product name
KHGMHEMB_01353 4.59e-147 - - - - - - - -
KHGMHEMB_01354 3.08e-266 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KHGMHEMB_01355 6.92e-276 - - - S - - - Cysteine-rich secretory protein family
KHGMHEMB_01356 1.34e-103 uspA - - T - - - universal stress protein
KHGMHEMB_01357 4.53e-55 - - - - - - - -
KHGMHEMB_01358 6.82e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KHGMHEMB_01359 1.83e-106 - - - S - - - Protein of unknown function (DUF1694)
KHGMHEMB_01360 1.52e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHGMHEMB_01361 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHGMHEMB_01362 7.44e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KHGMHEMB_01363 5.62e-294 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHGMHEMB_01364 1.5e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHGMHEMB_01365 2.27e-22 - - - K - - - Helix-turn-helix domain
KHGMHEMB_01379 4.33e-103 - - - - - - - -
KHGMHEMB_01380 3.64e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHGMHEMB_01381 2.48e-69 - - - GK - - - ROK family
KHGMHEMB_01382 4.7e-87 - - - GK - - - ROK family
KHGMHEMB_01383 5.78e-57 - - - - - - - -
KHGMHEMB_01384 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHGMHEMB_01385 5.79e-88 - - - S - - - Domain of unknown function (DUF1934)
KHGMHEMB_01386 1.25e-114 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHGMHEMB_01387 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHGMHEMB_01388 3.66e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHGMHEMB_01389 1.6e-41 - - - S - - - Haloacid dehalogenase-like hydrolase
KHGMHEMB_01390 6.1e-38 - - - S - - - Haloacid dehalogenase-like hydrolase
KHGMHEMB_01391 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_01392 4.05e-205 msmR - - K - - - AraC-like ligand binding domain
KHGMHEMB_01393 1.87e-288 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KHGMHEMB_01394 3.5e-138 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHGMHEMB_01395 4.27e-136 - - - K - - - DNA-binding helix-turn-helix protein
KHGMHEMB_01396 9.59e-258 - - - KLT - - - serine threonine protein kinase
KHGMHEMB_01397 0.0 - - - KLT - - - Protein kinase domain
KHGMHEMB_01398 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KHGMHEMB_01399 7.39e-82 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
KHGMHEMB_01400 1.89e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHGMHEMB_01401 1.54e-17 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease)
KHGMHEMB_01402 3.8e-84 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KHGMHEMB_01403 2.4e-76 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KHGMHEMB_01404 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KHGMHEMB_01405 3.91e-272 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
KHGMHEMB_01406 2.79e-54 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
KHGMHEMB_01407 1.41e-108 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
KHGMHEMB_01408 6.79e-146 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
KHGMHEMB_01409 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHGMHEMB_01410 6.61e-189 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KHGMHEMB_01411 1.05e-112 - - - - - - - -
KHGMHEMB_01412 2.6e-96 - - - - - - - -
KHGMHEMB_01413 7.25e-207 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
KHGMHEMB_01414 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHGMHEMB_01415 4.17e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
KHGMHEMB_01416 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KHGMHEMB_01417 1.96e-108 - - - M - - - NlpC/P60 family
KHGMHEMB_01418 4.79e-177 - - - EG - - - EamA-like transporter family
KHGMHEMB_01419 1.44e-141 - - - - - - - -
KHGMHEMB_01420 1.35e-102 - - - - - - - -
KHGMHEMB_01421 1.27e-313 ynbB - - P - - - aluminum resistance
KHGMHEMB_01422 1.91e-78 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
KHGMHEMB_01423 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
KHGMHEMB_01424 2.9e-237 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KHGMHEMB_01425 0.0 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_01426 1.7e-31 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHGMHEMB_01427 2.93e-234 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHGMHEMB_01428 9.39e-167 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KHGMHEMB_01429 1.22e-123 - - - K - - - Acetyltransferase (GNAT) domain
KHGMHEMB_01432 7.28e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KHGMHEMB_01433 4.17e-236 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
KHGMHEMB_01434 5e-118 ydhK - - M - - - Protein of unknown function (DUF1541)
KHGMHEMB_01435 1.49e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
KHGMHEMB_01436 2.08e-77 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
KHGMHEMB_01438 1.9e-52 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KHGMHEMB_01439 6.25e-170 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_01440 3.42e-197 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KHGMHEMB_01441 3.11e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHGMHEMB_01442 1.63e-62 - - - - - - - -
KHGMHEMB_01443 6.54e-171 - - - S - - - Uncharacterised protein family (UPF0236)
KHGMHEMB_01444 1.81e-167 - - - - - - - -
KHGMHEMB_01445 5.16e-40 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01446 2.87e-41 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KHGMHEMB_01447 4.73e-196 - - - S - - - Core-2/I-Branching enzyme
KHGMHEMB_01448 2.84e-47 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHGMHEMB_01449 2.03e-96 - - - - - - - -
KHGMHEMB_01450 2.06e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHGMHEMB_01451 5.85e-274 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KHGMHEMB_01452 1.93e-83 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHGMHEMB_01453 2.58e-81 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHGMHEMB_01454 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHGMHEMB_01455 4.19e-210 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01456 4.98e-49 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01457 4.65e-75 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01458 3.58e-237 ybcH - - D ko:K06889 - ko00000 Alpha beta
KHGMHEMB_01459 1.32e-20 - - - E - - - Amino acid permease
KHGMHEMB_01460 8.99e-210 - - - E - - - Amino acid permease
KHGMHEMB_01461 3.69e-69 - - - E - - - Amino acid permease
KHGMHEMB_01462 1.96e-206 - - - - - - - -
KHGMHEMB_01463 7.07e-106 - - - - - - - -
KHGMHEMB_01466 7.97e-25 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01467 6.11e-228 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01468 3.93e-73 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01469 3.44e-152 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
KHGMHEMB_01471 1.05e-165 - - - - - - - -
KHGMHEMB_01472 2.49e-53 - - - K - - - helix_turn_helix, arabinose operon control protein
KHGMHEMB_01473 5.44e-170 ycaM - - E - - - amino acid
KHGMHEMB_01474 2.36e-72 ycaM - - E - - - amino acid
KHGMHEMB_01475 2.14e-153 supH - - S - - - haloacid dehalogenase-like hydrolase
KHGMHEMB_01478 1.97e-83 - - - - - - - -
KHGMHEMB_01479 3.22e-51 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_01480 1.17e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_01481 1.98e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_01482 1.95e-140 - - - S - - - Protein of unknown function (DUF3232)
KHGMHEMB_01483 2.86e-74 - - - S - - - SLAP domain
KHGMHEMB_01484 1.39e-48 - - - - - - - -
KHGMHEMB_01485 2.18e-31 - - - K - - - Helix-turn-helix XRE-family like proteins
KHGMHEMB_01486 1.36e-153 - - - - - - - -
KHGMHEMB_01487 3.75e-98 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHGMHEMB_01488 4.79e-59 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_01491 5.03e-109 - - - S - - - SLAP domain
KHGMHEMB_01492 4.83e-35 - - - - - - - -
KHGMHEMB_01493 2.99e-272 - - - S - - - response to antibiotic
KHGMHEMB_01494 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHGMHEMB_01495 4.67e-313 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KHGMHEMB_01496 9.6e-73 - - - - - - - -
KHGMHEMB_01497 1.04e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KHGMHEMB_01498 1.12e-146 ybbB - - S - - - Protein of unknown function (DUF1211)
KHGMHEMB_01499 3.23e-218 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KHGMHEMB_01500 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHGMHEMB_01501 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHGMHEMB_01502 2.94e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHGMHEMB_01503 7.94e-271 camS - - S - - - sex pheromone
KHGMHEMB_01504 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHGMHEMB_01505 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KHGMHEMB_01506 1.19e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KHGMHEMB_01508 8.06e-115 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KHGMHEMB_01509 4.18e-177 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
KHGMHEMB_01510 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KHGMHEMB_01511 6.32e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHGMHEMB_01512 1.45e-66 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_01513 4.15e-119 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_01514 5.46e-249 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_01515 1.74e-68 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_01516 1.51e-120 - - - S - - - hydrolase
KHGMHEMB_01517 2.67e-184 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
KHGMHEMB_01518 4.57e-96 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHGMHEMB_01519 2.34e-94 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHGMHEMB_01520 7.06e-22 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KHGMHEMB_01521 6.01e-97 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KHGMHEMB_01522 2.8e-35 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KHGMHEMB_01523 2.51e-73 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KHGMHEMB_01524 7.86e-207 - - - S - - - Phospholipase, patatin family
KHGMHEMB_01525 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KHGMHEMB_01526 2.69e-86 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KHGMHEMB_01527 1.3e-37 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KHGMHEMB_01528 3.11e-84 - - - S - - - Enterocin A Immunity
KHGMHEMB_01529 7.49e-74 yitW - - S - - - Iron-sulfur cluster assembly protein
KHGMHEMB_01530 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KHGMHEMB_01531 1.29e-105 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KHGMHEMB_01532 7.78e-300 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHGMHEMB_01533 1.21e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
KHGMHEMB_01534 3.69e-187 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KHGMHEMB_01536 1.84e-166 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_01537 1.64e-150 - - - L - - - Belongs to the 'phage' integrase family
KHGMHEMB_01538 9.06e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHGMHEMB_01539 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHGMHEMB_01540 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHGMHEMB_01541 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHGMHEMB_01542 8.83e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHGMHEMB_01543 5.3e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHGMHEMB_01544 6.55e-82 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KHGMHEMB_01545 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHGMHEMB_01546 2.47e-274 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHGMHEMB_01547 1.63e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KHGMHEMB_01548 9.18e-317 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHGMHEMB_01549 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHGMHEMB_01550 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
KHGMHEMB_01551 6.59e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHGMHEMB_01552 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
KHGMHEMB_01553 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHGMHEMB_01554 1.08e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KHGMHEMB_01555 4.36e-67 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHGMHEMB_01556 3.75e-69 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01557 7.37e-100 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
KHGMHEMB_01559 7.93e-249 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
KHGMHEMB_01560 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
KHGMHEMB_01561 9.63e-270 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_01562 6.28e-222 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHGMHEMB_01563 1.01e-187 - - - K - - - SIS domain
KHGMHEMB_01564 1.81e-69 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KHGMHEMB_01565 1.1e-119 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHGMHEMB_01566 1.92e-122 - - - - - - - -
KHGMHEMB_01567 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHGMHEMB_01568 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHGMHEMB_01569 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHGMHEMB_01570 7.7e-80 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHGMHEMB_01571 3.46e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KHGMHEMB_01572 2e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHGMHEMB_01573 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHGMHEMB_01574 5.88e-44 - - - - - - - -
KHGMHEMB_01575 4.35e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHGMHEMB_01576 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHGMHEMB_01577 6.59e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHGMHEMB_01578 7.21e-173 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KHGMHEMB_01579 9.01e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KHGMHEMB_01580 2.92e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KHGMHEMB_01581 5.32e-266 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KHGMHEMB_01582 1.01e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KHGMHEMB_01583 2.66e-249 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHGMHEMB_01584 4.26e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHGMHEMB_01585 1.95e-191 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
KHGMHEMB_01586 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KHGMHEMB_01587 2.25e-302 ymfH - - S - - - Peptidase M16
KHGMHEMB_01588 2.18e-290 ymfF - - S - - - Peptidase M16 inactive domain protein
KHGMHEMB_01589 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KHGMHEMB_01590 4.46e-90 WQ51_03320 - - S - - - Protein of unknown function (DUF1149)
KHGMHEMB_01591 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHGMHEMB_01592 4.24e-270 XK27_05220 - - S - - - AI-2E family transporter
KHGMHEMB_01593 2.77e-31 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KHGMHEMB_01594 4.91e-37 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KHGMHEMB_01595 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
KHGMHEMB_01596 7.43e-258 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KHGMHEMB_01597 1.48e-151 - - - S - - - SNARE associated Golgi protein
KHGMHEMB_01598 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KHGMHEMB_01599 2.46e-218 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHGMHEMB_01600 3.06e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHGMHEMB_01601 4.88e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KHGMHEMB_01602 7.26e-146 - - - S - - - CYTH
KHGMHEMB_01603 3.88e-146 yjbH - - Q - - - Thioredoxin
KHGMHEMB_01604 3.22e-205 coiA - - S ko:K06198 - ko00000 Competence protein
KHGMHEMB_01605 5.25e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHGMHEMB_01606 1.54e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHGMHEMB_01607 3.33e-208 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHGMHEMB_01608 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
KHGMHEMB_01609 0.0 - - - E - - - Amino acid permease
KHGMHEMB_01610 1.02e-235 - - - S - - - Domain of unknown function DUF87
KHGMHEMB_01611 2.76e-103 - - - S - - - SIR2-like domain
KHGMHEMB_01612 1.66e-316 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KHGMHEMB_01613 9.74e-98 - - - S - - - Protein of unknown function (DUF3021)
KHGMHEMB_01614 1.96e-98 - - - K - - - LytTr DNA-binding domain
KHGMHEMB_01615 1.33e-46 - - - S - - - Plasmid maintenance system killer
KHGMHEMB_01616 4.8e-72 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
KHGMHEMB_01617 9.02e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_01618 4.61e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KHGMHEMB_01619 3.18e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHGMHEMB_01620 1.64e-72 ytpP - - CO - - - Thioredoxin
KHGMHEMB_01621 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHGMHEMB_01622 0.0 - - - - - - - -
KHGMHEMB_01623 2.07e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHGMHEMB_01624 1.08e-247 pbpX1 - - V - - - Beta-lactamase
KHGMHEMB_01625 0.0 - - - L - - - Helicase C-terminal domain protein
KHGMHEMB_01626 2.43e-34 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KHGMHEMB_01627 1.77e-56 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KHGMHEMB_01628 1.95e-42 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KHGMHEMB_01629 1.47e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KHGMHEMB_01630 1.6e-214 - - - G - - - Phosphotransferase enzyme family
KHGMHEMB_01631 1.86e-244 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHGMHEMB_01632 3.22e-80 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
KHGMHEMB_01633 6.96e-100 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
KHGMHEMB_01634 1.81e-52 fusA1 - - J - - - elongation factor G
KHGMHEMB_01635 5e-283 fusA1 - - J - - - elongation factor G
KHGMHEMB_01636 8.13e-84 fusA1 - - J - - - elongation factor G
KHGMHEMB_01637 2.1e-211 yvgN - - C - - - Aldo keto reductase
KHGMHEMB_01638 4.52e-138 - - - S - - - SLAP domain
KHGMHEMB_01639 1.78e-74 - - - S - - - SLAP domain
KHGMHEMB_01640 9.95e-183 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_01641 0.0 - - - H - - - ThiF family
KHGMHEMB_01642 2.1e-28 - - - H - - - ThiF family
KHGMHEMB_01644 1.68e-236 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KHGMHEMB_01648 1.15e-189 - - - G - - - Peptidase_C39 like family
KHGMHEMB_01649 8.86e-84 - - - M - - - NlpC/P60 family
KHGMHEMB_01650 1.1e-62 - - - M - - - NlpC/P60 family
KHGMHEMB_01651 1.66e-61 - - - - - - - -
KHGMHEMB_01652 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHGMHEMB_01653 6.45e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHGMHEMB_01654 1.07e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHGMHEMB_01655 5.46e-108 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHGMHEMB_01656 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KHGMHEMB_01657 1.08e-214 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KHGMHEMB_01658 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHGMHEMB_01659 2.83e-121 - - - - - - - -
KHGMHEMB_01660 4.51e-124 - - - - - - - -
KHGMHEMB_01661 1.53e-07 - - - S ko:K09707 - ko00000 ACT domain
KHGMHEMB_01662 2.37e-21 - - - S - - - Bacteriocin helveticin-J
KHGMHEMB_01663 3.33e-179 - - - S - - - Bacteriocin helveticin-J
KHGMHEMB_01664 9.13e-245 - - - S - - - SLAP domain
KHGMHEMB_01665 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KHGMHEMB_01666 3.15e-69 - - - S - - - Psort location Cytoplasmic, score
KHGMHEMB_01667 8.17e-286 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KHGMHEMB_01668 1.94e-152 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_01669 1.22e-25 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_01670 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_01671 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KHGMHEMB_01672 1.54e-294 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KHGMHEMB_01673 1.36e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KHGMHEMB_01674 3.27e-257 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KHGMHEMB_01675 2.69e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KHGMHEMB_01676 1.84e-237 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHGMHEMB_01677 1.01e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KHGMHEMB_01678 8.57e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHGMHEMB_01679 1.91e-179 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHGMHEMB_01680 1.62e-189 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KHGMHEMB_01681 1.57e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KHGMHEMB_01682 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHGMHEMB_01683 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHGMHEMB_01684 1.18e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KHGMHEMB_01685 1.32e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KHGMHEMB_01686 2.64e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KHGMHEMB_01687 1.32e-63 ylxQ - - J - - - ribosomal protein
KHGMHEMB_01688 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHGMHEMB_01689 1.37e-78 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHGMHEMB_01690 4.94e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHGMHEMB_01691 2.23e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KHGMHEMB_01692 2.99e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHGMHEMB_01693 2.3e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHGMHEMB_01694 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KHGMHEMB_01695 4.6e-271 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHGMHEMB_01696 2.08e-73 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KHGMHEMB_01697 7.14e-61 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KHGMHEMB_01698 5.58e-306 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KHGMHEMB_01699 1.62e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHGMHEMB_01700 0.0 qacA - - EGP - - - Major Facilitator
KHGMHEMB_01701 5.65e-276 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
KHGMHEMB_01702 1.07e-266 pepA - - E - - - M42 glutamyl aminopeptidase
KHGMHEMB_01703 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
KHGMHEMB_01704 1.18e-14 - - - - - - - -
KHGMHEMB_01705 1.51e-161 - - - - - - - -
KHGMHEMB_01706 9.13e-167 - - - F - - - glutamine amidotransferase
KHGMHEMB_01707 2.22e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHGMHEMB_01708 6.38e-97 - - - K - - - Transcriptional regulator, MarR family
KHGMHEMB_01709 9.14e-283 - - - S - - - SLAP domain
KHGMHEMB_01710 4.91e-304 - - - S - - - Domain of unknown function (DUF3883)
KHGMHEMB_01712 6.01e-112 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KHGMHEMB_01713 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KHGMHEMB_01714 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
KHGMHEMB_01715 3.51e-30 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
KHGMHEMB_01716 3.87e-12 - - - C - - - FMN-dependent dehydrogenase
KHGMHEMB_01717 2.67e-108 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
KHGMHEMB_01718 4.1e-31 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
KHGMHEMB_01719 2.14e-179 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHGMHEMB_01720 4.14e-72 - - - - - - - -
KHGMHEMB_01721 1.34e-193 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KHGMHEMB_01725 1.3e-199 yitS - - S - - - EDD domain protein, DegV family
KHGMHEMB_01726 1.81e-109 - - - K - - - Domain of unknown function (DUF1836)
KHGMHEMB_01727 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHGMHEMB_01728 3.42e-194 - - - - - - - -
KHGMHEMB_01729 2.35e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHGMHEMB_01730 1.01e-281 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHGMHEMB_01731 1.71e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHGMHEMB_01732 2.75e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KHGMHEMB_01733 1.59e-56 potE - - E - - - Amino Acid
KHGMHEMB_01734 1.3e-230 potE - - E - - - Amino Acid
KHGMHEMB_01735 1.21e-243 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHGMHEMB_01736 8.16e-314 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KHGMHEMB_01737 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
KHGMHEMB_01738 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KHGMHEMB_01739 7.34e-88 - - - K - - - DNA-binding transcription factor activity
KHGMHEMB_01740 7.51e-77 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
KHGMHEMB_01741 3.42e-24 - - - K - - - rpiR family
KHGMHEMB_01743 1.91e-151 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KHGMHEMB_01744 9.81e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KHGMHEMB_01745 1.83e-188 - - - S - - - haloacid dehalogenase-like hydrolase
KHGMHEMB_01746 2.18e-288 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHGMHEMB_01747 2.14e-220 - - - S ko:K07133 - ko00000 cog cog1373
KHGMHEMB_01748 1.57e-170 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KHGMHEMB_01750 8.43e-196 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KHGMHEMB_01751 1.12e-101 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHGMHEMB_01752 3.39e-111 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHGMHEMB_01753 5.07e-63 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHGMHEMB_01754 1.4e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHGMHEMB_01755 2.22e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
KHGMHEMB_01756 7.48e-10 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHGMHEMB_01757 2.31e-44 - - - S ko:K18918 - ko00000,ko02048,ko03000 RelB antitoxin
KHGMHEMB_01758 2.34e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHGMHEMB_01759 2.69e-165 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHGMHEMB_01760 1.9e-206 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHGMHEMB_01761 1.38e-120 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHGMHEMB_01762 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHGMHEMB_01763 9.8e-97 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KHGMHEMB_01764 2.56e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHGMHEMB_01765 7.51e-23 dar 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
KHGMHEMB_01766 5.17e-123 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
KHGMHEMB_01767 7.19e-280 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KHGMHEMB_01768 3.63e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KHGMHEMB_01771 3.11e-61 - - - S - - - PD-(D/E)XK nuclease family transposase
KHGMHEMB_01772 1.69e-180 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
KHGMHEMB_01773 4.75e-80 - - - - - - - -
KHGMHEMB_01774 2.57e-20 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
KHGMHEMB_01775 1.26e-125 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHGMHEMB_01776 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KHGMHEMB_01777 5.15e-236 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHGMHEMB_01778 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_01779 1.38e-59 - - - - - - - -
KHGMHEMB_01780 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
KHGMHEMB_01781 9.45e-178 - - - L - - - Transposase and inactivated derivatives, IS30 family
KHGMHEMB_01782 1.17e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHGMHEMB_01783 3.29e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHGMHEMB_01784 2.36e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KHGMHEMB_01785 4.2e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHGMHEMB_01786 3.42e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KHGMHEMB_01787 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHGMHEMB_01788 1.7e-32 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
KHGMHEMB_01789 1.12e-190 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KHGMHEMB_01790 2.07e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHGMHEMB_01791 3.19e-50 ynzC - - S - - - UPF0291 protein
KHGMHEMB_01792 3.18e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
KHGMHEMB_01796 3.89e-242 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
KHGMHEMB_01798 2.18e-20 - - - C - - - Flavodoxin
KHGMHEMB_01799 6.63e-88 - - - C - - - Flavodoxin
KHGMHEMB_01800 9.65e-193 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
KHGMHEMB_01801 1.87e-68 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHGMHEMB_01802 3.05e-21 - - - - - - - -
KHGMHEMB_01803 5.35e-247 - - - S - - - Bacteriocin helveticin-J
KHGMHEMB_01804 0.0 - - - M - - - Peptidase family M1 domain
KHGMHEMB_01805 2.89e-226 - - - S - - - SLAP domain
KHGMHEMB_01806 9.54e-206 - - - - - - - -
KHGMHEMB_01807 5.54e-212 - - - - - - - -
KHGMHEMB_01808 9.81e-175 - - - - - - - -
KHGMHEMB_01809 1.28e-181 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KHGMHEMB_01810 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KHGMHEMB_01811 4.12e-79 lysM - - M - - - LysM domain
KHGMHEMB_01812 1.49e-224 - - - - - - - -
KHGMHEMB_01813 3.23e-289 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KHGMHEMB_01814 1.12e-125 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_01815 3.83e-43 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHGMHEMB_01816 0.0 - - - V - - - Restriction endonuclease
KHGMHEMB_01817 5.14e-137 - - - K - - - Bacterial regulatory proteins, tetR family
KHGMHEMB_01818 1.37e-28 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_01819 2.67e-190 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHGMHEMB_01820 9.79e-119 - - - - - - - -
KHGMHEMB_01821 3.6e-35 - - - - - - - -
KHGMHEMB_01822 3.09e-66 - - - - - - - -
KHGMHEMB_01823 7.28e-209 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KHGMHEMB_01824 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KHGMHEMB_01825 1.2e-72 yheA - - S - - - Belongs to the UPF0342 family
KHGMHEMB_01826 6.08e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
KHGMHEMB_01827 0.0 yhaN - - L - - - AAA domain
KHGMHEMB_01828 2.85e-242 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHGMHEMB_01829 3.93e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KHGMHEMB_01830 1.97e-200 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHGMHEMB_01831 6.03e-57 - - - - - - - -
KHGMHEMB_01832 1.67e-104 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
KHGMHEMB_01833 2.34e-135 - 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHGMHEMB_01834 1.19e-19 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KHGMHEMB_01835 2.49e-118 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KHGMHEMB_01836 1.53e-162 - - - S - - - membrane
KHGMHEMB_01837 1.15e-103 - - - K - - - LytTr DNA-binding domain
KHGMHEMB_01838 5.63e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHGMHEMB_01839 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KHGMHEMB_01840 9.52e-18 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHGMHEMB_01841 4.17e-271 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHGMHEMB_01842 3.98e-45 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHGMHEMB_01843 6.05e-35 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHGMHEMB_01844 2.85e-92 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHGMHEMB_01845 5.17e-102 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHGMHEMB_01846 5.01e-299 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHGMHEMB_01847 1.9e-19 - - - S - - - Toxin ToxN, type III toxin-antitoxin system
KHGMHEMB_01848 3.56e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHGMHEMB_01849 8.23e-117 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHGMHEMB_01850 8.67e-111 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
KHGMHEMB_01851 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
KHGMHEMB_01852 1.07e-39 - - - - - - - -
KHGMHEMB_01853 2.64e-205 - - - I - - - alpha/beta hydrolase fold
KHGMHEMB_01854 3.02e-53 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHGMHEMB_01855 2.72e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KHGMHEMB_01856 2.76e-292 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KHGMHEMB_01857 1.99e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHGMHEMB_01858 5.44e-42 - - - K ko:K03710 - ko00000,ko03000 UTRA
KHGMHEMB_01860 4.12e-24 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KHGMHEMB_01861 8.11e-99 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KHGMHEMB_01862 9.63e-14 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KHGMHEMB_01863 2.22e-187 slpX - - S - - - SLAP domain
KHGMHEMB_01864 5.81e-119 - - - - - - - -
KHGMHEMB_01867 3.51e-273 - - - - - - - -
KHGMHEMB_01868 4.41e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
KHGMHEMB_01869 4.14e-81 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
KHGMHEMB_01870 4.73e-50 - - - - - - - -
KHGMHEMB_01871 1.13e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHGMHEMB_01872 1.26e-159 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KHGMHEMB_01873 2.67e-159 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KHGMHEMB_01874 2.1e-24 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KHGMHEMB_01875 1.82e-123 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KHGMHEMB_01876 1.68e-247 - - - G - - - Major Facilitator Superfamily
KHGMHEMB_01877 3.95e-28 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHGMHEMB_01878 2.89e-148 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHGMHEMB_01880 4.38e-108 - - - S - - - Short repeat of unknown function (DUF308)
KHGMHEMB_01881 7.3e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KHGMHEMB_01882 1.09e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KHGMHEMB_01883 8.23e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KHGMHEMB_01884 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHGMHEMB_01885 0.0 - - - S - - - SH3-like domain
KHGMHEMB_01886 1.21e-144 - - - G - - - phosphoglycerate mutase
KHGMHEMB_01887 1.45e-182 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
KHGMHEMB_01888 1.06e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KHGMHEMB_01889 2.33e-156 - - - - - - - -
KHGMHEMB_01890 2.74e-66 - - - C - - - Domain of unknown function (DUF4931)
KHGMHEMB_01891 1.04e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KHGMHEMB_01892 9.28e-317 - - - S - - - Putative threonine/serine exporter
KHGMHEMB_01893 2.92e-231 citR - - K - - - Putative sugar-binding domain
KHGMHEMB_01894 7.12e-69 - - - - - - - -
KHGMHEMB_01895 3.82e-23 - - - - - - - -
KHGMHEMB_01896 8.1e-87 - - - S - - - Domain of unknown function DUF1828
KHGMHEMB_01897 8.93e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KHGMHEMB_01898 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_01899 1.89e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KHGMHEMB_01900 1.01e-24 - - - - - - - -
KHGMHEMB_01901 3.56e-93 ytwI - - S - - - Protein of unknown function (DUF441)
KHGMHEMB_01902 5.9e-56 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHGMHEMB_01903 8.72e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KHGMHEMB_01904 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KHGMHEMB_01905 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KHGMHEMB_01906 6.74e-153 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHGMHEMB_01907 8.72e-174 - - - K ko:K03492 - ko00000,ko03000 UTRA
KHGMHEMB_01908 1.2e-75 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHGMHEMB_01909 1.04e-132 - - - S - - - Uncharacterised protein family (UPF0236)
KHGMHEMB_01910 8.67e-73 - - - M - - - Rib/alpha-like repeat
KHGMHEMB_01911 8.57e-52 - - - - - - - -
KHGMHEMB_01912 7.84e-82 - - - - - - - -
KHGMHEMB_01913 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHGMHEMB_01914 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KHGMHEMB_01915 4.36e-199 - - - I - - - Alpha/beta hydrolase family
KHGMHEMB_01916 4.99e-251 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KHGMHEMB_01917 2.27e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
KHGMHEMB_01918 2.18e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
KHGMHEMB_01919 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
KHGMHEMB_01920 2.32e-194 - - - - - - - -
KHGMHEMB_01921 4.93e-291 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHGMHEMB_01922 8.05e-100 - - - K ko:K03710 - ko00000,ko03000 UTRA
KHGMHEMB_01923 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHGMHEMB_01924 1.01e-79 ynbB - - P - - - aluminum resistance
KHGMHEMB_01925 2.5e-26 ynbB - - P - - - aluminum resistance
KHGMHEMB_01926 1.87e-146 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01927 5.2e-108 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01928 8.42e-204 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
KHGMHEMB_01929 3.37e-82 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHGMHEMB_01930 1.27e-165 - - - L ko:K07485 - ko00000 Transposase
KHGMHEMB_01931 2.65e-131 - - - L - - - Resolvase, N terminal domain
KHGMHEMB_01932 4.53e-41 - - - S - - - Transglycosylase associated protein
KHGMHEMB_01933 1.29e-240 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
KHGMHEMB_01934 5.77e-102 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHGMHEMB_01935 5.05e-104 - - - K - - - Transcriptional regulator
KHGMHEMB_01936 7.42e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHGMHEMB_01937 6.25e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHGMHEMB_01938 8.57e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KHGMHEMB_01939 4.42e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KHGMHEMB_01940 1.09e-293 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHGMHEMB_01941 2.13e-101 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHGMHEMB_01942 6.93e-96 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KHGMHEMB_01943 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
KHGMHEMB_01944 1.78e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHGMHEMB_01945 3.69e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
KHGMHEMB_01946 7.68e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KHGMHEMB_01947 3.2e-241 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHGMHEMB_01948 1.33e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KHGMHEMB_01949 5.31e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHGMHEMB_01950 8.61e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KHGMHEMB_01951 1.02e-78 - - - - - - - -
KHGMHEMB_01952 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHGMHEMB_01953 4.26e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHGMHEMB_01954 3.67e-313 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KHGMHEMB_01955 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHGMHEMB_01956 2.52e-81 - - - S - - - Protein of unknown function (DUF2974)
KHGMHEMB_01957 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_01958 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHGMHEMB_01959 1.63e-194 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHGMHEMB_01960 2.39e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHGMHEMB_01962 3.25e-96 gntR - - K - - - UbiC transcription regulator-associated domain protein
KHGMHEMB_01963 9.58e-28 gntR - - K - - - UbiC transcription regulator-associated domain protein
KHGMHEMB_01964 6.08e-224 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
KHGMHEMB_01965 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHGMHEMB_01966 9.41e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHGMHEMB_01967 1.47e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHGMHEMB_01968 1.26e-209 - - - C - - - Domain of unknown function (DUF4931)
KHGMHEMB_01969 3.04e-26 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KHGMHEMB_01973 2.14e-29 - - - - - - - -
KHGMHEMB_01974 6.17e-30 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
KHGMHEMB_01975 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHGMHEMB_01976 1.94e-67 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHGMHEMB_01977 6e-178 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHGMHEMB_01978 6.13e-210 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
KHGMHEMB_01979 5.83e-162 yleF - - K - - - Helix-turn-helix domain, rpiR family
KHGMHEMB_01980 8.09e-235 - - - S - - - AAA domain
KHGMHEMB_01981 2.41e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHGMHEMB_01982 1.16e-31 - - - - - - - -
KHGMHEMB_01983 9.17e-210 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KHGMHEMB_01984 7.75e-161 - - - G - - - Belongs to the phosphoglycerate mutase family
KHGMHEMB_01985 4.26e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
KHGMHEMB_01986 2.01e-18 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHGMHEMB_01987 8.02e-85 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHGMHEMB_01988 3.63e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KHGMHEMB_01989 2.01e-81 yhaH - - S - - - Protein of unknown function (DUF805)
KHGMHEMB_01990 1.01e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KHGMHEMB_01991 2.27e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHGMHEMB_01992 3.86e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHGMHEMB_01993 4.28e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHGMHEMB_01994 2.15e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHGMHEMB_01995 1.19e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHGMHEMB_01996 3.16e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KHGMHEMB_01997 4.41e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHGMHEMB_01998 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHGMHEMB_01999 1.46e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHGMHEMB_02000 3.15e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KHGMHEMB_02001 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHGMHEMB_02002 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHGMHEMB_02003 5.1e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHGMHEMB_02004 1.73e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHGMHEMB_02005 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KHGMHEMB_02006 2.63e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHGMHEMB_02007 1.28e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHGMHEMB_02008 5.05e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHGMHEMB_02009 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHGMHEMB_02010 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHGMHEMB_02011 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHGMHEMB_02012 1.15e-43 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHGMHEMB_02013 4.24e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHGMHEMB_02014 6.37e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHGMHEMB_02015 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KHGMHEMB_02016 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHGMHEMB_02017 7.45e-158 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHGMHEMB_02018 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHGMHEMB_02019 4.33e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHGMHEMB_02020 5.7e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHGMHEMB_02021 4.67e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHGMHEMB_02022 3.85e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KHGMHEMB_02023 3.29e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHGMHEMB_02024 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KHGMHEMB_02025 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHGMHEMB_02026 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHGMHEMB_02027 7.28e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHGMHEMB_02028 1.02e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KHGMHEMB_02029 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
KHGMHEMB_02030 3.78e-34 - - - - - - - -
KHGMHEMB_02032 3.12e-187 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KHGMHEMB_02033 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHGMHEMB_02035 1.63e-76 - - - - - - - -
KHGMHEMB_02036 5.32e-25 - - - - - - - -
KHGMHEMB_02037 5.33e-210 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHGMHEMB_02038 6.35e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHGMHEMB_02039 1.24e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KHGMHEMB_02040 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHGMHEMB_02041 1.14e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHGMHEMB_02042 2.7e-279 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KHGMHEMB_02043 2.94e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KHGMHEMB_02044 9.49e-317 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHGMHEMB_02045 2.87e-05 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KHGMHEMB_02046 5.68e-57 - - - S - - - Protein of unknown function (DUF3290)
KHGMHEMB_02047 3.3e-15 - - - S - - - Protein of unknown function (DUF3290)
KHGMHEMB_02048 1.63e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KHGMHEMB_02049 0.0 - - - V - - - ABC transporter transmembrane region
KHGMHEMB_02050 2.91e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KHGMHEMB_02051 5.1e-240 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KHGMHEMB_02052 2.65e-123 - - - F - - - Nucleoside 2-deoxyribosyltransferase
KHGMHEMB_02054 1.55e-89 - - - S - - - Peptidase propeptide and YPEB domain
KHGMHEMB_02055 1.69e-275 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHGMHEMB_02056 5.59e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHGMHEMB_02057 5.55e-219 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KHGMHEMB_02058 3.38e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
KHGMHEMB_02059 4.94e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
KHGMHEMB_02060 1.06e-192 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KHGMHEMB_02061 1.57e-141 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
KHGMHEMB_02062 5.19e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KHGMHEMB_02063 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHGMHEMB_02064 1.1e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KHGMHEMB_02065 4.36e-162 gpm2 - - G - - - Phosphoglycerate mutase family
KHGMHEMB_02066 1.08e-307 - - - S - - - response to antibiotic
KHGMHEMB_02067 1.84e-162 - - - - - - - -
KHGMHEMB_02068 6.14e-106 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_02069 1.98e-27 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_02070 7.96e-120 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHGMHEMB_02071 3.21e-27 - - - - - - - -
KHGMHEMB_02072 7.24e-22 - - - - - - - -
KHGMHEMB_02073 2.34e-241 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
KHGMHEMB_02074 1.87e-51 - - - - - - - -
KHGMHEMB_02075 8.26e-60 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)