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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DBDHBBOL_00001	9.32e-125	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
DBDHBBOL_00002	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBDHBBOL_00003	8.32e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBDHBBOL_00004	8.82e-34	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBDHBBOL_00005	3.24e-88	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
DBDHBBOL_00006	5.96e-99	ubiE	-	-	Q	-	-	-	Mycolic acid cyclopropane synthetase
DBDHBBOL_00007	1.28e-39	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
DBDHBBOL_00010	2.21e-26	-	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00011	3.58e-28	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
DBDHBBOL_00032	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DBDHBBOL_00033	7.24e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DBDHBBOL_00034	3.38e-253	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DBDHBBOL_00035	2.95e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
DBDHBBOL_00036	1.36e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DBDHBBOL_00037	1.11e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBDHBBOL_00038	1.17e-215	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DBDHBBOL_00039	2.99e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DBDHBBOL_00040	2.08e-203	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DBDHBBOL_00041	2.35e-122	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DBDHBBOL_00042	5.33e-184	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DBDHBBOL_00043	7.23e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DBDHBBOL_00044	1.03e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DBDHBBOL_00045	4.11e-97	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DBDHBBOL_00046	6.14e-74	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DBDHBBOL_00047	1.95e-22	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
DBDHBBOL_00048	2.27e-27	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
DBDHBBOL_00049	4.03e-30	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
DBDHBBOL_00050	1.4e-26	-	-	-	S	-	-	-	Plasmid maintenance system killer
DBDHBBOL_00052	4.36e-67	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DBDHBBOL_00053	6.38e-149	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DBDHBBOL_00054	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00055	6.52e-70	-	-	-	S	-	-	-	FMN_bind
DBDHBBOL_00057	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DBDHBBOL_00058	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
DBDHBBOL_00059	1.63e-74	-	-	-	-	-	-	-	-
DBDHBBOL_00061	3.91e-31	-	-	-	-	-	-	-	-
DBDHBBOL_00062	2.6e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DBDHBBOL_00063	2.95e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DBDHBBOL_00064	8.71e-317	-	-	-	EGP	-	-	-	Major Facilitator
DBDHBBOL_00065	2.22e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DBDHBBOL_00066	5.67e-65	-	-	-	-	-	-	-	-
DBDHBBOL_00067	7.31e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBDHBBOL_00068	1.54e-179	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBDHBBOL_00069	4.2e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DBDHBBOL_00070	3.42e-162	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DBDHBBOL_00071	8.63e-136	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase
DBDHBBOL_00073	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DBDHBBOL_00074	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DBDHBBOL_00075	2.68e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DBDHBBOL_00076	8.7e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00077	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DBDHBBOL_00078	1.92e-269	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DBDHBBOL_00079	5.49e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DBDHBBOL_00080	3.39e-184	yycI	-	-	S	-	-	-	YycH protein
DBDHBBOL_00081	3.63e-306	yycH	-	-	S	-	-	-	YycH protein
DBDHBBOL_00082	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DBDHBBOL_00083	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DBDHBBOL_00086	9.16e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
DBDHBBOL_00087	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DBDHBBOL_00088	2.13e-106	lytE	-	-	M	-	-	-	Lysin motif
DBDHBBOL_00089	3.53e-192	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DBDHBBOL_00090	2.9e-263	oatA	-	-	I	-	-	-	Acyltransferase
DBDHBBOL_00091	2.55e-68	-	-	-	-	-	-	-	-
DBDHBBOL_00092	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DBDHBBOL_00093	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBDHBBOL_00094	8e-150	ybbR	-	-	S	-	-	-	YbbR-like protein
DBDHBBOL_00095	2.67e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DBDHBBOL_00096	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DBDHBBOL_00097	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DBDHBBOL_00098	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DBDHBBOL_00099	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DBDHBBOL_00100	2.79e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DBDHBBOL_00101	2.62e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DBDHBBOL_00102	2.02e-140	-	-	-	-	-	-	-	-
DBDHBBOL_00103	3.83e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DBDHBBOL_00104	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DBDHBBOL_00105	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DBDHBBOL_00106	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DBDHBBOL_00107	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DBDHBBOL_00108	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DBDHBBOL_00109	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DBDHBBOL_00110	2.85e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DBDHBBOL_00111	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DBDHBBOL_00112	9.05e-22	-	-	-	-	-	-	-	-
DBDHBBOL_00113	2.13e-256	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DBDHBBOL_00114	9.62e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DBDHBBOL_00115	1.23e-95	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
DBDHBBOL_00116	2.34e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00117	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
DBDHBBOL_00118	1.73e-136	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DBDHBBOL_00119	4.65e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00120	2.18e-129	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
DBDHBBOL_00121	8.99e-188	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DBDHBBOL_00122	4.78e-249	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DBDHBBOL_00123	8.26e-243	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DBDHBBOL_00124	3.93e-220	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DBDHBBOL_00125	4.65e-256	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
DBDHBBOL_00126	3.03e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DBDHBBOL_00127	3.07e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DBDHBBOL_00128	1.89e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
DBDHBBOL_00129	2.68e-202	-	-	-	S	-	-	-	DUF218 domain
DBDHBBOL_00131	1.02e-78	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DBDHBBOL_00132	3.37e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DBDHBBOL_00133	0.000137	-	-	-	S	-	-	-	Phage minor structural protein GP20
DBDHBBOL_00134	1.46e-180	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBDHBBOL_00135	2.31e-125	-	-	-	S	-	-	-	Pfam:DUF3816
DBDHBBOL_00136	1.3e-83	-	-	-	L	-	-	-	Resolvase, N-terminal domain
DBDHBBOL_00137	4.84e-115	-	-	-	L	-	-	-	Probable transposase
DBDHBBOL_00138	7.8e-181	-	-	-	G	-	-	-	MucBP domain
DBDHBBOL_00139	2.95e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DBDHBBOL_00140	2.12e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DBDHBBOL_00141	1.22e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBDHBBOL_00142	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
DBDHBBOL_00143	2.18e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DBDHBBOL_00144	5.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
DBDHBBOL_00145	5.67e-198	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DBDHBBOL_00146	1.31e-149	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DBDHBBOL_00147	5.79e-29	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DBDHBBOL_00149	2.47e-147	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
DBDHBBOL_00150	8.14e-146	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
DBDHBBOL_00151	9.07e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
DBDHBBOL_00152	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DBDHBBOL_00153	9.61e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DBDHBBOL_00154	3.59e-284	-	-	-	P	-	-	-	Chloride transporter, ClC family
DBDHBBOL_00155	1.96e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DBDHBBOL_00156	1.56e-48	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DBDHBBOL_00158	3.69e-120	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DBDHBBOL_00159	1.65e-61	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DBDHBBOL_00160	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DBDHBBOL_00161	8.03e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DBDHBBOL_00162	5.16e-101	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DBDHBBOL_00163	1.51e-138	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBDHBBOL_00164	8.02e-62	-	-	-	-	-	-	-	-
DBDHBBOL_00165	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DBDHBBOL_00166	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
DBDHBBOL_00167	3.69e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DBDHBBOL_00168	7.81e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBDHBBOL_00169	3.37e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DBDHBBOL_00170	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DBDHBBOL_00171	1.16e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DBDHBBOL_00172	2.04e-157	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DBDHBBOL_00173	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DBDHBBOL_00174	1.33e-122	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DBDHBBOL_00175	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBDHBBOL_00176	3.06e-261	yacL	-	-	S	-	-	-	domain protein
DBDHBBOL_00177	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBDHBBOL_00178	1.94e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
DBDHBBOL_00179	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DBDHBBOL_00180	2.52e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DBDHBBOL_00181	1.18e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBDHBBOL_00182	5.35e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
DBDHBBOL_00183	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DBDHBBOL_00184	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DBDHBBOL_00185	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DBDHBBOL_00186	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DBDHBBOL_00187	5.61e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DBDHBBOL_00189	8.35e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DBDHBBOL_00190	1.16e-280	-	-	-	EGP	-	-	-	Major Facilitator
DBDHBBOL_00192	3.23e-225	-	-	-	L	-	-	-	helicase activity
DBDHBBOL_00193	1.95e-270	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
DBDHBBOL_00194	9.01e-82	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DBDHBBOL_00195	1.34e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DBDHBBOL_00196	2.7e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00197	4.65e-255	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBDHBBOL_00198	4.37e-137	-	-	-	C	-	-	-	aldo keto reductase
DBDHBBOL_00199	1.02e-142	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
DBDHBBOL_00200	9.47e-122	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBDHBBOL_00201	1.99e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DBDHBBOL_00202	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
DBDHBBOL_00203	3.32e-115	-	-	-	-	-	-	-	-
DBDHBBOL_00204	2.14e-32	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
DBDHBBOL_00205	1.08e-108	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DBDHBBOL_00206	1.39e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
DBDHBBOL_00207	6.37e-21	-	-	-	-	-	-	-	-
DBDHBBOL_00208	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DBDHBBOL_00209	7.32e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBDHBBOL_00210	2.03e-159	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DBDHBBOL_00211	2.66e-80	-	-	-	-	-	-	-	-
DBDHBBOL_00212	9.55e-143	yicL	-	-	EG	-	-	-	EamA-like transporter family
DBDHBBOL_00213	1.18e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
DBDHBBOL_00214	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DBDHBBOL_00215	1.84e-212	-	-	-	K	-	-	-	LysR substrate binding domain
DBDHBBOL_00216	5.28e-202	rssA	-	-	S	-	-	-	Phospholipase, patatin family
DBDHBBOL_00218	3.43e-279	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DBDHBBOL_00220	1.17e-122	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DBDHBBOL_00221	1.39e-125	-	-	-	K	-	-	-	Virulence activator alpha C-term
DBDHBBOL_00222	1.61e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DBDHBBOL_00223	5.44e-71	-	-	-	S	-	-	-	SNARE associated Golgi protein
DBDHBBOL_00224	1.14e-296	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DBDHBBOL_00225	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DBDHBBOL_00227	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DBDHBBOL_00228	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DBDHBBOL_00229	2.54e-245	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBDHBBOL_00230	1.41e-66	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
DBDHBBOL_00231	1.53e-72	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DBDHBBOL_00232	3.84e-61	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
DBDHBBOL_00233	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DBDHBBOL_00234	4.53e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DBDHBBOL_00235	8.65e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DBDHBBOL_00236	2.93e-147	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DBDHBBOL_00237	1.27e-207	-	-	-	EG	-	-	-	EamA-like transporter family
DBDHBBOL_00238	1.8e-310	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
DBDHBBOL_00240	9.92e-110	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
DBDHBBOL_00241	2.68e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DBDHBBOL_00242	7.06e-120	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
DBDHBBOL_00243	2.24e-66	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DBDHBBOL_00244	1.29e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DBDHBBOL_00245	2.53e-113	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DBDHBBOL_00246	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DBDHBBOL_00247	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DBDHBBOL_00248	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DBDHBBOL_00249	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DBDHBBOL_00250	1.17e-193	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DBDHBBOL_00251	1.67e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DBDHBBOL_00252	5.7e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DBDHBBOL_00253	5.05e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
DBDHBBOL_00254	5.58e-104	-	-	-	-	-	-	-	-
DBDHBBOL_00256	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBDHBBOL_00257	2.7e-194	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBDHBBOL_00258	4.28e-259	-	-	-	EGP	-	-	-	Major Facilitator
DBDHBBOL_00259	1.09e-174	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
DBDHBBOL_00260	2.84e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DBDHBBOL_00261	6.32e-181	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00262	3.29e-34	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBDHBBOL_00265	2.87e-34	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DBDHBBOL_00266	1.28e-32	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DBDHBBOL_00267	1.34e-59	-	-	-	GM	-	-	-	NmrA-like family
DBDHBBOL_00268	7.28e-44	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DBDHBBOL_00270	8.38e-123	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
DBDHBBOL_00271	4.41e-187	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
DBDHBBOL_00272	7.82e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
DBDHBBOL_00273	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DBDHBBOL_00274	2.21e-19	-	-	-	-	-	-	-	-
DBDHBBOL_00275	1.82e-73	-	-	-	-	-	-	-	-
DBDHBBOL_00276	6.98e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
DBDHBBOL_00277	3.27e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DBDHBBOL_00278	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DBDHBBOL_00279	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DBDHBBOL_00280	8.74e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DBDHBBOL_00281	2.8e-230	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
DBDHBBOL_00282	6.78e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DBDHBBOL_00283	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00284	1.44e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DBDHBBOL_00286	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DBDHBBOL_00287	1.59e-245	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
DBDHBBOL_00288	6.38e-94	-	-	-	O	-	-	-	OsmC-like protein
DBDHBBOL_00289	5.7e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DBDHBBOL_00290	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00291	7.19e-199	-	-	-	-	-	-	-	-
DBDHBBOL_00292	4.83e-10	-	-	-	-	-	-	-	-
DBDHBBOL_00293	5.14e-77	-	-	-	-	-	-	-	-
DBDHBBOL_00294	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
DBDHBBOL_00296	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DBDHBBOL_00297	1.57e-313	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00298	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBDHBBOL_00299	1.62e-173	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
DBDHBBOL_00300	2.13e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DBDHBBOL_00301	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBDHBBOL_00302	4.53e-244	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DBDHBBOL_00303	2.65e-54	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
DBDHBBOL_00304	9.39e-57	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DBDHBBOL_00305	1.1e-162	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DBDHBBOL_00306	1.21e-138	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
DBDHBBOL_00307	3e-180	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
DBDHBBOL_00308	1.27e-52	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DBDHBBOL_00309	8.53e-70	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DBDHBBOL_00310	3.29e-19	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DBDHBBOL_00311	9.84e-167	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
DBDHBBOL_00312	8.34e-101	-	-	-	-	-	-	-	-
DBDHBBOL_00313	9.64e-178	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DBDHBBOL_00316	5.49e-11	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DBDHBBOL_00317	7.11e-105	-	-	-	-	-	-	-	-
DBDHBBOL_00318	4.78e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DBDHBBOL_00319	4.54e-70	-	-	-	K	-	-	-	Helix-turn-helix domain
DBDHBBOL_00320	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DBDHBBOL_00321	6.49e-247	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
DBDHBBOL_00322	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DBDHBBOL_00323	8.88e-138	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBDHBBOL_00325	6.22e-24	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DBDHBBOL_00326	6.84e-100	mleR	-	-	K	-	-	-	LysR family
DBDHBBOL_00327	2.18e-289	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DBDHBBOL_00328	3.97e-235	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DBDHBBOL_00329	3.53e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DBDHBBOL_00330	9.29e-283	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DBDHBBOL_00331	4.32e-268	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DBDHBBOL_00332	7.13e-288	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DBDHBBOL_00333	1.52e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
DBDHBBOL_00334	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DBDHBBOL_00335	4.68e-153	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
DBDHBBOL_00336	2.25e-240	-	-	-	I	-	-	-	Alpha beta
DBDHBBOL_00337	5.34e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
DBDHBBOL_00338	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DBDHBBOL_00340	1.12e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DBDHBBOL_00341	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
DBDHBBOL_00342	5.25e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
DBDHBBOL_00343	2.07e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
DBDHBBOL_00344	1.29e-313	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DBDHBBOL_00345	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
DBDHBBOL_00346	3.88e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DBDHBBOL_00347	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DBDHBBOL_00348	1.14e-95	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DBDHBBOL_00349	2.83e-78	-	-	-	-	-	-	-	-
DBDHBBOL_00350	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBDHBBOL_00351	4.5e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DBDHBBOL_00352	5.42e-27	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
DBDHBBOL_00353	2.91e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DBDHBBOL_00354	4.51e-140	-	-	-	S	-	-	-	VIT family
DBDHBBOL_00355	3.6e-148	-	-	-	S	-	-	-	membrane
DBDHBBOL_00357	1.65e-69	-	-	-	C	-	-	-	FMN binding
DBDHBBOL_00358	1.02e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DBDHBBOL_00361	1.68e-60	-	-	-	-	-	-	-	-
DBDHBBOL_00362	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DBDHBBOL_00363	3.97e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DBDHBBOL_00364	8.21e-174	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DBDHBBOL_00365	1.01e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBDHBBOL_00366	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DBDHBBOL_00367	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DBDHBBOL_00368	9.73e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DBDHBBOL_00369	9e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DBDHBBOL_00370	7.65e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DBDHBBOL_00371	6.31e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DBDHBBOL_00372	3.43e-147	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DBDHBBOL_00373	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DBDHBBOL_00374	1.62e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
DBDHBBOL_00375	7.23e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBDHBBOL_00376	1.25e-157	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DBDHBBOL_00377	1.07e-141	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DBDHBBOL_00378	2.66e-72	cadD	-	-	P	-	-	-	Cadmium resistance transporter
DBDHBBOL_00379	1.12e-31	cadD	-	-	P	-	-	-	Cadmium resistance transporter
DBDHBBOL_00380	1.81e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DBDHBBOL_00381	1.43e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBDHBBOL_00382	2.76e-33	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00383	3.13e-30	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00384	1.24e-54	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00385	6.16e-66	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
DBDHBBOL_00388	4.35e-238	-	-	-	-	-	-	-	-
DBDHBBOL_00389	1.44e-159	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DBDHBBOL_00390	2.18e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
DBDHBBOL_00391	1.36e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DBDHBBOL_00392	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBDHBBOL_00393	3.16e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DBDHBBOL_00394	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DBDHBBOL_00395	1.15e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DBDHBBOL_00396	7.5e-201	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DBDHBBOL_00397	1.11e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DBDHBBOL_00398	7.44e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DBDHBBOL_00399	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
DBDHBBOL_00400	3.54e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DBDHBBOL_00401	1.29e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DBDHBBOL_00402	2.02e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBDHBBOL_00403	7.13e-76	-	-	-	-	-	-	-	-
DBDHBBOL_00404	3.76e-180	yidA	-	-	S	-	-	-	hydrolase
DBDHBBOL_00405	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DBDHBBOL_00406	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DBDHBBOL_00407	3.57e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DBDHBBOL_00408	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DBDHBBOL_00409	1.46e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBDHBBOL_00410	1.1e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DBDHBBOL_00411	8.34e-153	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
DBDHBBOL_00412	4.85e-29	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DBDHBBOL_00413	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DBDHBBOL_00414	4.28e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBDHBBOL_00415	6.76e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DBDHBBOL_00416	3.15e-201	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DBDHBBOL_00417	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DBDHBBOL_00418	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DBDHBBOL_00419	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DBDHBBOL_00420	2.44e-265	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBDHBBOL_00421	2.38e-73	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DBDHBBOL_00422	3.71e-147	-	-	-	S	-	-	-	(CBS) domain
DBDHBBOL_00423	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DBDHBBOL_00424	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DBDHBBOL_00425	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
DBDHBBOL_00426	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DBDHBBOL_00427	9.54e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DBDHBBOL_00428	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DBDHBBOL_00429	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DBDHBBOL_00430	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBDHBBOL_00431	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DBDHBBOL_00432	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBDHBBOL_00433	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DBDHBBOL_00435	1.86e-84	-	-	-	-	-	-	-	-
DBDHBBOL_00436	7.46e-92	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
DBDHBBOL_00437	1.67e-146	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DBDHBBOL_00438	1.82e-228	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00439	8.56e-11	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
DBDHBBOL_00440	9.81e-209	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
DBDHBBOL_00441	1.93e-47	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
DBDHBBOL_00442	4.16e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF2877)
DBDHBBOL_00443	1.58e-104	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
DBDHBBOL_00444	7.13e-32	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
DBDHBBOL_00445	7.95e-222	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
DBDHBBOL_00446	1.11e-159	-	-	-	C	-	-	-	nitroreductase
DBDHBBOL_00447	2.22e-173	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DBDHBBOL_00448	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
DBDHBBOL_00449	2.57e-251	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DBDHBBOL_00450	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DBDHBBOL_00451	1.76e-35	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
DBDHBBOL_00452	8.75e-158	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
DBDHBBOL_00453	7.53e-34	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DBDHBBOL_00454	4e-84	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DBDHBBOL_00455	5.09e-209	-	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00457	5.63e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DBDHBBOL_00459	4.31e-195	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DBDHBBOL_00460	1.75e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DBDHBBOL_00461	0.0	-	-	-	L	-	-	-	DNA helicase
DBDHBBOL_00462	7.63e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DBDHBBOL_00463	2.35e-126	-	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_00464	9.87e-20	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DBDHBBOL_00465	7.25e-46	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DBDHBBOL_00466	1.25e-61	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
DBDHBBOL_00467	8.95e-57	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DBDHBBOL_00468	3.57e-119	-	-	-	K	-	-	-	transcriptional regulator
DBDHBBOL_00469	4.95e-161	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DBDHBBOL_00470	3.7e-229	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DBDHBBOL_00471	3.02e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
DBDHBBOL_00472	1.11e-41	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DBDHBBOL_00474	8.3e-110	-	-	-	K	-	-	-	GNAT family
DBDHBBOL_00475	9.62e-154	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
DBDHBBOL_00476	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
DBDHBBOL_00477	1.06e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DBDHBBOL_00478	2.05e-165	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
DBDHBBOL_00480	1.55e-74	-	-	-	-	-	-	-	-
DBDHBBOL_00482	3.24e-10	-	-	-	-	-	-	-	-
DBDHBBOL_00483	2.41e-101	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
DBDHBBOL_00484	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00485	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DBDHBBOL_00486	2.54e-243	ampC	-	-	V	-	-	-	Beta-lactamase
DBDHBBOL_00487	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBDHBBOL_00488	1.29e-60	-	-	-	-	-	-	-	-
DBDHBBOL_00489	1.51e-180	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
DBDHBBOL_00490	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
DBDHBBOL_00491	2.53e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DBDHBBOL_00492	2.08e-205	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DBDHBBOL_00493	3.72e-201	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DBDHBBOL_00494	2.66e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DBDHBBOL_00495	3.14e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBDHBBOL_00496	1.11e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DBDHBBOL_00497	5.26e-248	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DBDHBBOL_00498	5.5e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DBDHBBOL_00499	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DBDHBBOL_00500	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DBDHBBOL_00501	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBDHBBOL_00502	1.77e-76	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DBDHBBOL_00503	3.51e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBDHBBOL_00504	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBDHBBOL_00505	1.4e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DBDHBBOL_00506	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBDHBBOL_00507	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DBDHBBOL_00508	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
DBDHBBOL_00509	3.06e-274	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
DBDHBBOL_00510	1.56e-232	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DBDHBBOL_00511	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DBDHBBOL_00512	1.99e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DBDHBBOL_00514	2.04e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DBDHBBOL_00515	1.32e-271	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DBDHBBOL_00516	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DBDHBBOL_00517	9.55e-144	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
DBDHBBOL_00518	3.32e-101	dltr	-	-	K	-	-	-	response regulator
DBDHBBOL_00519	7.27e-165	sptS	-	-	T	-	-	-	Histidine kinase
DBDHBBOL_00520	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DBDHBBOL_00521	7.71e-133	-	-	-	K	-	-	-	acetyltransferase
DBDHBBOL_00522	7.11e-173	-	-	-	IQ	-	-	-	dehydrogenase reductase
DBDHBBOL_00523	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DBDHBBOL_00524	9.54e-205	-	-	-	EG	-	-	-	EamA-like transporter family
DBDHBBOL_00525	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DBDHBBOL_00526	2.4e-151	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DBDHBBOL_00527	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
DBDHBBOL_00528	7.69e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBDHBBOL_00529	9.47e-261	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DBDHBBOL_00530	6.88e-171	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DBDHBBOL_00531	0.0	-	-	-	E	-	-	-	amino acid
DBDHBBOL_00532	1.75e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00533	2.1e-177	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
DBDHBBOL_00534	1.07e-150	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
DBDHBBOL_00535	3.83e-234	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
DBDHBBOL_00537	2.02e-100	-	-	-	-	-	-	-	-
DBDHBBOL_00538	2.63e-212	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DBDHBBOL_00539	1.11e-35	-	-	-	-	-	-	-	-
DBDHBBOL_00540	2.68e-135	-	-	-	-	-	-	-	-
DBDHBBOL_00541	1.88e-125	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBDHBBOL_00542	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
DBDHBBOL_00543	1.25e-72	-	-	-	-	-	-	-	-
DBDHBBOL_00544	1.9e-160	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
DBDHBBOL_00546	3.21e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DBDHBBOL_00547	1.16e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DBDHBBOL_00548	4.81e-255	-	-	-	S	-	-	-	associated with various cellular activities
DBDHBBOL_00549	3.26e-266	-	-	-	S	-	-	-	Putative metallopeptidase domain
DBDHBBOL_00550	2.01e-59	-	-	-	-	-	-	-	-
DBDHBBOL_00551	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DBDHBBOL_00552	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DBDHBBOL_00553	7.85e-117	ymdB	-	-	S	-	-	-	Macro domain protein
DBDHBBOL_00554	1.19e-185	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DBDHBBOL_00555	1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DBDHBBOL_00556	5.76e-215	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00557	9.08e-71	-	-	-	-	-	-	-	-
DBDHBBOL_00558	3.64e-179	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DBDHBBOL_00559	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DBDHBBOL_00560	4.83e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00561	1.21e-48	-	-	-	-	-	-	-	-
DBDHBBOL_00562	2.85e-124	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DBDHBBOL_00563	7.97e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DBDHBBOL_00564	1.45e-86	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DBDHBBOL_00565	7.12e-81	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
DBDHBBOL_00566	1.37e-308	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00567	5.66e-58	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DBDHBBOL_00568	4.49e-53	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DBDHBBOL_00569	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DBDHBBOL_00571	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
DBDHBBOL_00572	1.03e-304	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
DBDHBBOL_00573	1.14e-310	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DBDHBBOL_00574	4.51e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DBDHBBOL_00575	5.11e-98	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DBDHBBOL_00576	2.59e-97	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DBDHBBOL_00577	9.19e-91	-	-	-	S	-	-	-	Belongs to the HesB IscA family
DBDHBBOL_00578	7.62e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DBDHBBOL_00579	2.08e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DBDHBBOL_00580	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DBDHBBOL_00581	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DBDHBBOL_00582	2.14e-133	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DBDHBBOL_00583	2.67e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DBDHBBOL_00584	7.48e-197	-	-	-	D	-	-	-	DNA integration
DBDHBBOL_00585	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBDHBBOL_00586	4.05e-209	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DBDHBBOL_00587	2.91e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBDHBBOL_00588	4.02e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DBDHBBOL_00589	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DBDHBBOL_00590	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DBDHBBOL_00591	3.9e-214	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DBDHBBOL_00592	1.2e-146	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
DBDHBBOL_00593	3.13e-273	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
DBDHBBOL_00594	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DBDHBBOL_00595	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DBDHBBOL_00596	1.12e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DBDHBBOL_00597	1.25e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DBDHBBOL_00598	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00599	2.82e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DBDHBBOL_00600	2.87e-199	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DBDHBBOL_00601	6.91e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DBDHBBOL_00602	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DBDHBBOL_00603	2.48e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DBDHBBOL_00604	5.39e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DBDHBBOL_00605	4.44e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DBDHBBOL_00606	4.66e-74	-	-	-	M	-	-	-	Lysin motif
DBDHBBOL_00607	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DBDHBBOL_00608	7.7e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
DBDHBBOL_00609	1.37e-110	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DBDHBBOL_00610	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DBDHBBOL_00611	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DBDHBBOL_00612	4.82e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DBDHBBOL_00613	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DBDHBBOL_00614	4.15e-182	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DBDHBBOL_00615	7.31e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DBDHBBOL_00616	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DBDHBBOL_00617	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DBDHBBOL_00619	4.74e-304	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DBDHBBOL_00620	4.94e-244	mocA	-	-	S	-	-	-	Oxidoreductase
DBDHBBOL_00621	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DBDHBBOL_00622	1.22e-132	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DBDHBBOL_00623	2.92e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DBDHBBOL_00624	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DBDHBBOL_00625	4.4e-172	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DBDHBBOL_00626	4.77e-43	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DBDHBBOL_00627	1.2e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DBDHBBOL_00628	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DBDHBBOL_00629	5.03e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DBDHBBOL_00630	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DBDHBBOL_00631	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DBDHBBOL_00632	6.76e-80	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBDHBBOL_00633	1.08e-55	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBDHBBOL_00634	6.15e-161	-	-	-	S	-	-	-	Membrane
DBDHBBOL_00635	3.18e-299	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DBDHBBOL_00636	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DBDHBBOL_00637	3.25e-227	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DBDHBBOL_00638	2.47e-127	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00639	1.33e-180	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DBDHBBOL_00640	1.43e-75	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DBDHBBOL_00641	5.56e-198	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
DBDHBBOL_00642	2.16e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
DBDHBBOL_00643	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
DBDHBBOL_00644	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBDHBBOL_00645	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DBDHBBOL_00646	1.2e-264	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DBDHBBOL_00647	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
DBDHBBOL_00648	1.77e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DBDHBBOL_00649	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DBDHBBOL_00650	2.39e-116	-	-	-	GM	-	-	-	epimerase
DBDHBBOL_00651	2.71e-109	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DBDHBBOL_00652	2.07e-196	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DBDHBBOL_00653	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DBDHBBOL_00654	2.19e-166	-	-	-	-	-	-	-	-
DBDHBBOL_00655	6.01e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBDHBBOL_00656	7.38e-167	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DBDHBBOL_00657	4.85e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DBDHBBOL_00658	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DBDHBBOL_00659	1.32e-85	-	-	-	-	-	-	-	-
DBDHBBOL_00661	2.56e-239	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
DBDHBBOL_00662	9.85e-165	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
DBDHBBOL_00663	4.03e-175	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
DBDHBBOL_00664	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DBDHBBOL_00665	2.31e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
DBDHBBOL_00666	1.4e-135	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
DBDHBBOL_00667	7.03e-98	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
DBDHBBOL_00668	5.6e-139	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DBDHBBOL_00669	7.78e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
DBDHBBOL_00670	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DBDHBBOL_00671	6.6e-230	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DBDHBBOL_00672	2.53e-191	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DBDHBBOL_00673	3.24e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00674	8.85e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DBDHBBOL_00675	2.93e-69	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
DBDHBBOL_00676	7.6e-209	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
DBDHBBOL_00677	5.36e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DBDHBBOL_00678	1.61e-41	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DBDHBBOL_00679	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DBDHBBOL_00680	9.88e-57	-	-	-	-	-	-	-	-
DBDHBBOL_00681	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DBDHBBOL_00682	5.45e-80	-	-	-	S	-	-	-	Domain of unknown function DUF302
DBDHBBOL_00683	1.15e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DBDHBBOL_00684	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DBDHBBOL_00685	4.21e-273	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DBDHBBOL_00686	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DBDHBBOL_00687	4.77e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DBDHBBOL_00688	4.78e-272	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DBDHBBOL_00689	4.92e-44	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
DBDHBBOL_00690	6.9e-29	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
DBDHBBOL_00691	7.32e-271	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DBDHBBOL_00692	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DBDHBBOL_00693	4.23e-270	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DBDHBBOL_00694	3.83e-38	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00695	4e-139	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_00696	1.03e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DBDHBBOL_00697	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBDHBBOL_00698	4.36e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DBDHBBOL_00699	7.74e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DBDHBBOL_00700	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DBDHBBOL_00701	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DBDHBBOL_00702	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DBDHBBOL_00703	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBDHBBOL_00705	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DBDHBBOL_00706	1.93e-62	-	-	-	-	-	-	-	-
DBDHBBOL_00707	3.01e-15	-	-	-	-	-	-	-	-
DBDHBBOL_00708	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DBDHBBOL_00710	1.87e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DBDHBBOL_00711	1.57e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
DBDHBBOL_00712	1.42e-114	-	-	-	GM	-	-	-	NAD(P)H-binding
DBDHBBOL_00713	7.27e-62	-	-	-	GM	-	-	-	NAD(P)H-binding
DBDHBBOL_00714	5.9e-192	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DBDHBBOL_00716	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DBDHBBOL_00717	3.92e-270	-	-	-	G	-	-	-	Major Facilitator Superfamily
DBDHBBOL_00718	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
DBDHBBOL_00719	4.24e-269	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DBDHBBOL_00720	1.56e-131	-	-	-	-	-	-	-	-
DBDHBBOL_00721	3.58e-111	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DBDHBBOL_00722	4.81e-140	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DBDHBBOL_00723	9.48e-210	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
DBDHBBOL_00724	3.82e-82	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
DBDHBBOL_00725	1.39e-92	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	aldo keto reductase
DBDHBBOL_00726	3.41e-45	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
DBDHBBOL_00727	2.12e-63	-	-	-	C	-	-	-	Flavodoxin
DBDHBBOL_00728	7.58e-115	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
DBDHBBOL_00729	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DBDHBBOL_00730	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
DBDHBBOL_00731	3.13e-126	-	-	-	-	-	-	-	-
DBDHBBOL_00732	1.54e-166	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DBDHBBOL_00733	3.98e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DBDHBBOL_00734	1.45e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
DBDHBBOL_00735	3.31e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DBDHBBOL_00736	1.1e-199	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DBDHBBOL_00737	4.64e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DBDHBBOL_00738	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DBDHBBOL_00739	1.8e-39	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
DBDHBBOL_00740	3.35e-80	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
DBDHBBOL_00741	3.7e-70	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
DBDHBBOL_00742	4.72e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DBDHBBOL_00743	4.91e-214	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DBDHBBOL_00744	3.96e-253	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DBDHBBOL_00745	9.94e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DBDHBBOL_00746	1.83e-195	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DBDHBBOL_00747	9.56e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DBDHBBOL_00748	1.44e-53	yphH	-	-	S	-	-	-	Cupin domain
DBDHBBOL_00749	1.12e-14	yphH	-	-	S	-	-	-	Cupin domain
DBDHBBOL_00750	4.89e-238	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBDHBBOL_00751	1.03e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DBDHBBOL_00752	2.5e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DBDHBBOL_00753	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DBDHBBOL_00754	7.47e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DBDHBBOL_00755	1.53e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DBDHBBOL_00756	6.84e-227	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DBDHBBOL_00757	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DBDHBBOL_00758	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
DBDHBBOL_00759	4.15e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DBDHBBOL_00760	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DBDHBBOL_00761	3.26e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBDHBBOL_00762	2.51e-165	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DBDHBBOL_00763	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DBDHBBOL_00764	9.05e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DBDHBBOL_00765	3.39e-49	-	-	-	-	-	-	-	-
DBDHBBOL_00766	0.0	ydaO	-	-	E	-	-	-	amino acid
DBDHBBOL_00767	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DBDHBBOL_00768	8.11e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBDHBBOL_00769	2.31e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DBDHBBOL_00770	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DBDHBBOL_00771	5.3e-218	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DBDHBBOL_00772	2.77e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DBDHBBOL_00773	1.81e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
DBDHBBOL_00774	1.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DBDHBBOL_00775	5.31e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DBDHBBOL_00776	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DBDHBBOL_00777	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DBDHBBOL_00778	2e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DBDHBBOL_00779	1.09e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DBDHBBOL_00780	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DBDHBBOL_00781	1.6e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DBDHBBOL_00782	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBDHBBOL_00783	1.86e-219	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBDHBBOL_00784	1.54e-96	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DBDHBBOL_00785	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DBDHBBOL_00787	1.22e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBDHBBOL_00788	1.08e-140	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DBDHBBOL_00789	6.55e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DBDHBBOL_00790	2.1e-270	arcT	-	-	E	-	-	-	Aminotransferase
DBDHBBOL_00791	2.21e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DBDHBBOL_00792	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
DBDHBBOL_00793	5.72e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
DBDHBBOL_00794	5.55e-216	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
DBDHBBOL_00795	6.95e-238	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DBDHBBOL_00796	3.72e-201	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
DBDHBBOL_00797	7.03e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBDHBBOL_00798	2.65e-218	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DBDHBBOL_00799	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DBDHBBOL_00800	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DBDHBBOL_00801	5.27e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DBDHBBOL_00802	3.85e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DBDHBBOL_00803	3.51e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DBDHBBOL_00804	1.31e-244	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DBDHBBOL_00805	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DBDHBBOL_00806	9.42e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DBDHBBOL_00807	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DBDHBBOL_00808	1.31e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DBDHBBOL_00809	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DBDHBBOL_00810	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBDHBBOL_00812	2.08e-105	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DBDHBBOL_00813	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DBDHBBOL_00814	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBDHBBOL_00815	1.04e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBDHBBOL_00816	2.35e-158	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
DBDHBBOL_00817	1.23e-107	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DBDHBBOL_00818	3.88e-260	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DBDHBBOL_00819	1.53e-310	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
DBDHBBOL_00820	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DBDHBBOL_00821	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DBDHBBOL_00822	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBDHBBOL_00823	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DBDHBBOL_00824	5.93e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DBDHBBOL_00825	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DBDHBBOL_00826	2.06e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DBDHBBOL_00827	2.97e-41	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DBDHBBOL_00828	9.78e-106	-	-	-	S	-	-	-	Putative threonine/serine exporter
DBDHBBOL_00829	6.11e-36	-	-	-	S	-	-	-	Putative threonine/serine exporter
DBDHBBOL_00830	5.52e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DBDHBBOL_00831	3e-147	-	-	-	I	-	-	-	phosphatase
DBDHBBOL_00832	2.83e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DBDHBBOL_00834	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DBDHBBOL_00835	1.35e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DBDHBBOL_00841	2.42e-113	-	-	-	IQ	-	-	-	reductase
DBDHBBOL_00842	1.18e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DBDHBBOL_00843	3.92e-68	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DBDHBBOL_00844	7.94e-92	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
DBDHBBOL_00845	2.33e-71	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
DBDHBBOL_00846	2.29e-142	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DBDHBBOL_00847	8.6e-05	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	acetyltransferase, isoleucine patch superfamily
DBDHBBOL_00848	7.02e-15	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DBDHBBOL_00849	2.12e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
DBDHBBOL_00850	1.14e-168	XK27_07210	-	-	S	-	-	-	B3 4 domain
DBDHBBOL_00851	4.58e-246	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DBDHBBOL_00852	7.12e-69	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBDHBBOL_00853	4.77e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBDHBBOL_00854	7.21e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DBDHBBOL_00855	1.55e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DBDHBBOL_00856	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DBDHBBOL_00857	1.96e-162	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
DBDHBBOL_00858	1.93e-214	-	-	-	GK	-	-	-	ROK family
DBDHBBOL_00859	4.58e-54	-	-	-	-	-	-	-	-
DBDHBBOL_00860	1.03e-106	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DBDHBBOL_00862	7.55e-70	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
DBDHBBOL_00864	1.59e-217	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
DBDHBBOL_00865	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DBDHBBOL_00866	7.81e-300	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DBDHBBOL_00867	1.19e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
DBDHBBOL_00868	1.31e-79	-	-	-	-	-	-	-	-
DBDHBBOL_00869	1.2e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
DBDHBBOL_00870	1.69e-124	-	-	-	V	-	-	-	VanZ like family
DBDHBBOL_00871	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DBDHBBOL_00872	4.29e-68	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DBDHBBOL_00873	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
DBDHBBOL_00874	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
DBDHBBOL_00875	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
DBDHBBOL_00876	6.36e-108	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DBDHBBOL_00877	6.2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
DBDHBBOL_00878	2.3e-173	-	-	-	S	-	-	-	Membrane
DBDHBBOL_00879	5.82e-188	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBDHBBOL_00880	7.54e-09	-	-	-	-	-	-	-	-
DBDHBBOL_00881	1.2e-138	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DBDHBBOL_00882	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DBDHBBOL_00883	2.18e-268	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DBDHBBOL_00884	5.35e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBDHBBOL_00885	3.95e-278	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
DBDHBBOL_00886	2.6e-259	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DBDHBBOL_00887	8.92e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DBDHBBOL_00888	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DBDHBBOL_00889	6.93e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DBDHBBOL_00890	4.71e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DBDHBBOL_00891	7.59e-195	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DBDHBBOL_00892	3.73e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DBDHBBOL_00893	1.73e-294	-	-	-	V	-	-	-	MatE
DBDHBBOL_00894	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DBDHBBOL_00895	5.62e-155	csrR	-	-	K	-	-	-	response regulator
DBDHBBOL_00896	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DBDHBBOL_00897	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DBDHBBOL_00898	3.94e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DBDHBBOL_00899	2.47e-173	yqeM	-	-	Q	-	-	-	Methyltransferase
DBDHBBOL_00900	2.79e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DBDHBBOL_00901	2.25e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DBDHBBOL_00902	5.4e-119	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DBDHBBOL_00903	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DBDHBBOL_00904	5.17e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DBDHBBOL_00905	4.65e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DBDHBBOL_00906	4.27e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DBDHBBOL_00907	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DBDHBBOL_00908	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DBDHBBOL_00909	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DBDHBBOL_00910	3.63e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DBDHBBOL_00911	6.63e-313	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DBDHBBOL_00912	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DBDHBBOL_00913	9.38e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DBDHBBOL_00914	1.53e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DBDHBBOL_00915	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBDHBBOL_00916	7.72e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
DBDHBBOL_00917	5.05e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DBDHBBOL_00918	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DBDHBBOL_00919	1.11e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DBDHBBOL_00920	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
DBDHBBOL_00921	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
DBDHBBOL_00922	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DBDHBBOL_00923	2.26e-267	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DBDHBBOL_00924	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00925	1.44e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DBDHBBOL_00927	6.37e-190	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DBDHBBOL_00928	2.13e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DBDHBBOL_00929	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DBDHBBOL_00930	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DBDHBBOL_00931	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DBDHBBOL_00933	7.31e-48	-	-	-	-	-	-	-	-
DBDHBBOL_00935	4.95e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
DBDHBBOL_00936	4.2e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
DBDHBBOL_00937	2.96e-302	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DBDHBBOL_00938	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
DBDHBBOL_00939	1.25e-119	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DBDHBBOL_00940	2.44e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DBDHBBOL_00941	6.8e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DBDHBBOL_00942	1.83e-234	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DBDHBBOL_00943	1.21e-143	-	-	-	-	-	-	-	-
DBDHBBOL_00944	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DBDHBBOL_00945	2.73e-232	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DBDHBBOL_00946	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DBDHBBOL_00947	3.9e-111	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DBDHBBOL_00948	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DBDHBBOL_00949	2.44e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DBDHBBOL_00950	3.34e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DBDHBBOL_00951	2.72e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DBDHBBOL_00952	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DBDHBBOL_00953	7.74e-204	-	-	-	EG	-	-	-	EamA-like transporter family
DBDHBBOL_00954	1.75e-223	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DBDHBBOL_00955	8.97e-189	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DBDHBBOL_00956	6.59e-170	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
DBDHBBOL_00957	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DBDHBBOL_00958	5.48e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
DBDHBBOL_00959	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DBDHBBOL_00960	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DBDHBBOL_00961	3.61e-210	-	-	-	C	-	-	-	Aldo keto reductase
DBDHBBOL_00962	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DBDHBBOL_00963	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DBDHBBOL_00964	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBDHBBOL_00965	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
DBDHBBOL_00966	4.71e-47	-	-	-	-	-	-	-	-
DBDHBBOL_00967	8.98e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DBDHBBOL_00968	3.27e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_00969	1.34e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
DBDHBBOL_00970	1.21e-243	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DBDHBBOL_00971	4.78e-87	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_00972	1.47e-112	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
DBDHBBOL_00973	4.59e-28	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DBDHBBOL_00974	1.07e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DBDHBBOL_00975	1.32e-257	-	-	-	F	ko:K03458	-	ko00000	Permease
DBDHBBOL_00976	1.89e-207	-	-	-	H	-	-	-	Acyl-protein synthetase, LuxE
DBDHBBOL_00977	1.96e-250	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
DBDHBBOL_00978	7.11e-144	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
DBDHBBOL_00979	1.11e-25	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
DBDHBBOL_00984	3.45e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DBDHBBOL_00985	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DBDHBBOL_00986	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DBDHBBOL_00987	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBDHBBOL_00988	1.44e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DBDHBBOL_00989	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DBDHBBOL_00990	1.5e-145	-	-	-	-	-	-	-	-
DBDHBBOL_00993	3.09e-208	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DBDHBBOL_00994	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DBDHBBOL_00995	1.38e-208	-	-	-	D	-	-	-	nuclear chromosome segregation
DBDHBBOL_00996	8.75e-37	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DBDHBBOL_01001	3.48e-06	-	-	-	D	-	-	-	nuclear chromosome segregation
DBDHBBOL_01002	1.34e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBDHBBOL_01003	1.09e-150	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DBDHBBOL_01004	1.37e-269	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DBDHBBOL_01005	1.45e-260	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DBDHBBOL_01006	1.6e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DBDHBBOL_01007	2.64e-130	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DBDHBBOL_01008	2.42e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DBDHBBOL_01009	2.58e-115	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DBDHBBOL_01010	2.81e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DBDHBBOL_01011	9.34e-230	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DBDHBBOL_01012	1.01e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DBDHBBOL_01013	1.32e-292	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DBDHBBOL_01014	1.75e-130	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBDHBBOL_01015	3.64e-235	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
DBDHBBOL_01016	7.14e-141	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
DBDHBBOL_01017	4.87e-166	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
DBDHBBOL_01018	3.19e-14	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
DBDHBBOL_01019	7.57e-200	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DBDHBBOL_01023	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DBDHBBOL_01024	2.71e-151	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DBDHBBOL_01025	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DBDHBBOL_01026	3.31e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DBDHBBOL_01027	1.52e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DBDHBBOL_01028	4.47e-255	-	-	-	-	-	-	-	-
DBDHBBOL_01029	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DBDHBBOL_01030	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DBDHBBOL_01032	1.24e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DBDHBBOL_01033	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DBDHBBOL_01034	1.36e-149	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DBDHBBOL_01035	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DBDHBBOL_01036	2.63e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
DBDHBBOL_01037	2.93e-211	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
DBDHBBOL_01038	1.51e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DBDHBBOL_01039	2.55e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DBDHBBOL_01040	1.07e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DBDHBBOL_01041	1.95e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DBDHBBOL_01042	3.45e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DBDHBBOL_01043	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
DBDHBBOL_01044	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DBDHBBOL_01045	2.34e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBDHBBOL_01046	1.76e-200	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DBDHBBOL_01047	9.83e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DBDHBBOL_01048	2.45e-226	-	-	-	K	-	-	-	WYL domain
DBDHBBOL_01049	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DBDHBBOL_01050	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DBDHBBOL_01051	9.58e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DBDHBBOL_01052	2.09e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DBDHBBOL_01053	3.14e-258	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DBDHBBOL_01054	1.18e-275	-	-	-	G	-	-	-	Transporter, major facilitator family protein
DBDHBBOL_01055	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DBDHBBOL_01056	1.71e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DBDHBBOL_01057	8.72e-71	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
DBDHBBOL_01059	1.21e-233	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
DBDHBBOL_01060	3.08e-137	citR	-	-	K	-	-	-	sugar-binding domain protein
DBDHBBOL_01061	9.32e-191	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DBDHBBOL_01062	2.81e-139	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DBDHBBOL_01063	2.02e-109	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DBDHBBOL_01064	1.08e-48	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DBDHBBOL_01065	5.01e-185	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DBDHBBOL_01066	5.7e-300	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DBDHBBOL_01067	2.88e-167	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DBDHBBOL_01068	7.51e-89	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DBDHBBOL_01069	4.23e-136	-	-	-	L	-	-	-	Integrase
DBDHBBOL_01070	3.74e-58	-	-	-	K	-	-	-	transcriptional regulator
DBDHBBOL_01071	3.47e-113	-	-	-	GM	-	-	-	NmrA-like family
DBDHBBOL_01072	2.06e-46	-	-	-	C	-	-	-	Flavodoxin
DBDHBBOL_01073	8.85e-154	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DBDHBBOL_01074	7.13e-05	-	-	-	-	-	-	-	-
DBDHBBOL_01075	9.35e-50	-	-	-	-	-	-	-	-
DBDHBBOL_01076	3.49e-195	-	-	-	M	-	-	-	hydrolase, family 25
DBDHBBOL_01080	1.86e-70	-	-	-	-	-	-	-	-
DBDHBBOL_01084	2.25e-77	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
DBDHBBOL_01085	3.92e-183	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
DBDHBBOL_01086	1.46e-100	-	-	-	S	-	-	-	Phage tail protein
DBDHBBOL_01087	8.13e-285	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DBDHBBOL_01089	1.45e-62	-	-	-	S	-	-	-	Phage tail tube protein
DBDHBBOL_01090	1.46e-28	-	-	-	-	-	-	-	-
DBDHBBOL_01091	1.61e-25	-	-	-	-	-	-	-	-
DBDHBBOL_01092	1.26e-43	-	-	-	S	-	-	-	Phage head-tail joining protein
DBDHBBOL_01093	1.76e-39	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DBDHBBOL_01094	1.14e-153	-	-	-	S	-	-	-	Phage capsid family
DBDHBBOL_01095	1.22e-99	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
DBDHBBOL_01096	1.36e-180	-	-	-	S	-	-	-	portal protein
DBDHBBOL_01098	0.0	-	-	-	S	-	-	-	Phage Terminase
DBDHBBOL_01099	3.82e-52	-	-	-	L	-	-	-	Phage terminase, small subunit
DBDHBBOL_01100	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DBDHBBOL_01101	2.52e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DBDHBBOL_01102	3.07e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DBDHBBOL_01103	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DBDHBBOL_01104	8.46e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DBDHBBOL_01105	7.68e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DBDHBBOL_01106	6.61e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DBDHBBOL_01107	4.99e-91	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
DBDHBBOL_01110	2.96e-11	-	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DBDHBBOL_01111	2.58e-24	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DBDHBBOL_01113	1.58e-07	-	-	-	-	-	-	-	-
DBDHBBOL_01116	1.69e-83	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
DBDHBBOL_01117	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DBDHBBOL_01118	2.17e-297	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DBDHBBOL_01119	8.27e-254	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DBDHBBOL_01120	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
DBDHBBOL_01121	3.3e-203	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
DBDHBBOL_01122	1.22e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBDHBBOL_01123	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DBDHBBOL_01124	2.25e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DBDHBBOL_01125	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DBDHBBOL_01126	2.57e-07	-	-	-	U	ko:K03297	-	ko00000,ko02000	Small multidrug resistance protein
DBDHBBOL_01127	1.76e-31	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DBDHBBOL_01137	2.6e-77	-	-	-	S	-	-	-	branched-chain amino acid
DBDHBBOL_01138	1.97e-176	-	-	-	E	-	-	-	AzlC protein
DBDHBBOL_01139	1.79e-264	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DBDHBBOL_01140	3.31e-262	hpk31	-	-	T	-	-	-	Histidine kinase
DBDHBBOL_01141	1.44e-156	vanR	-	-	K	-	-	-	response regulator
DBDHBBOL_01142	7.88e-121	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
DBDHBBOL_01143	2.12e-132	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
DBDHBBOL_01144	9.39e-118	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
DBDHBBOL_01145	6.69e-102	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DBDHBBOL_01146	5.46e-148	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
DBDHBBOL_01147	3.7e-75	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DBDHBBOL_01148	1.45e-32	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
DBDHBBOL_01149	1.18e-222	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DBDHBBOL_01150	7.64e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DBDHBBOL_01151	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DBDHBBOL_01152	4.63e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01154	5.28e-68	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DBDHBBOL_01155	5.13e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DBDHBBOL_01156	2.3e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DBDHBBOL_01157	5.48e-298	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DBDHBBOL_01158	2.01e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DBDHBBOL_01159	2.89e-202	-	-	-	S	-	-	-	Tetratricopeptide repeat
DBDHBBOL_01160	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBDHBBOL_01161	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DBDHBBOL_01162	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DBDHBBOL_01163	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DBDHBBOL_01164	1.58e-209	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
DBDHBBOL_01165	8.6e-235	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
DBDHBBOL_01166	5.11e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DBDHBBOL_01167	1.94e-115	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
DBDHBBOL_01168	3.77e-246	flp	-	-	V	-	-	-	Beta-lactamase
DBDHBBOL_01169	1.79e-287	-	-	-	-	-	-	-	-
DBDHBBOL_01171	1.2e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DBDHBBOL_01172	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBDHBBOL_01173	2.35e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
DBDHBBOL_01174	9.16e-208	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DBDHBBOL_01175	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DBDHBBOL_01177	1.32e-191	-	-	-	S	-	-	-	Phage integrase family
DBDHBBOL_01178	3.15e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
DBDHBBOL_01179	4.53e-224	-	-	-	-	-	-	-	-
DBDHBBOL_01180	5.44e-201	-	-	-	-	-	-	-	-
DBDHBBOL_01181	4.76e-19	-	-	-	-	-	-	-	-
DBDHBBOL_01182	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DBDHBBOL_01183	6.75e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DBDHBBOL_01184	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DBDHBBOL_01185	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DBDHBBOL_01186	6.12e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DBDHBBOL_01187	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DBDHBBOL_01188	7.33e-136	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DBDHBBOL_01189	3.66e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DBDHBBOL_01190	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DBDHBBOL_01191	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DBDHBBOL_01192	0.0	-	-	-	S	-	-	-	membrane
DBDHBBOL_01193	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DBDHBBOL_01194	2.41e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DBDHBBOL_01195	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DBDHBBOL_01196	1.05e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DBDHBBOL_01197	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DBDHBBOL_01198	2.96e-116	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DBDHBBOL_01199	3.34e-88	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBDHBBOL_01200	2.82e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DBDHBBOL_01201	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
DBDHBBOL_01203	1.27e-49	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DBDHBBOL_01204	3.77e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DBDHBBOL_01205	3.19e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DBDHBBOL_01207	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBDHBBOL_01208	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
DBDHBBOL_01209	7.85e-79	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DBDHBBOL_01210	1.89e-08	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DBDHBBOL_01211	9.85e-198	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
DBDHBBOL_01212	3.35e-69	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DBDHBBOL_01213	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DBDHBBOL_01214	2.1e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DBDHBBOL_01215	2.73e-80	-	-	-	-	-	-	-	-
DBDHBBOL_01216	1.57e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DBDHBBOL_01217	1.19e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DBDHBBOL_01218	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DBDHBBOL_01219	3.28e-263	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DBDHBBOL_01220	3.27e-125	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DBDHBBOL_01221	1.76e-85	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DBDHBBOL_01222	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBDHBBOL_01223	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
DBDHBBOL_01224	8.61e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DBDHBBOL_01225	1.59e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBDHBBOL_01226	6.75e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
DBDHBBOL_01227	2.39e-146	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DBDHBBOL_01228	2.04e-253	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
DBDHBBOL_01229	7.37e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBDHBBOL_01230	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
DBDHBBOL_01231	1.2e-217	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DBDHBBOL_01233	5.47e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01234	8.46e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
DBDHBBOL_01235	6e-216	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DBDHBBOL_01236	4.38e-100	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DBDHBBOL_01237	4.25e-126	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
DBDHBBOL_01238	7.45e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DBDHBBOL_01239	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DBDHBBOL_01240	1.01e-208	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DBDHBBOL_01241	1.17e-222	yueF	-	-	S	-	-	-	AI-2E family transporter
DBDHBBOL_01242	1.89e-203	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
DBDHBBOL_01243	2.99e-10	-	-	-	-	-	-	-	-
DBDHBBOL_01244	3.71e-74	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
DBDHBBOL_01245	2.52e-26	-	-	-	-	-	-	-	-
DBDHBBOL_01246	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBDHBBOL_01247	1.15e-103	-	-	-	L	-	-	-	nuclease
DBDHBBOL_01248	1.23e-196	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DBDHBBOL_01249	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DBDHBBOL_01250	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBDHBBOL_01251	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBDHBBOL_01252	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DBDHBBOL_01253	3.07e-284	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DBDHBBOL_01254	1.2e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DBDHBBOL_01255	9.56e-120	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
DBDHBBOL_01256	8.65e-274	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DBDHBBOL_01257	1.95e-119	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
DBDHBBOL_01258	2.72e-83	-	-	-	IQ	-	-	-	Dehydrogenase
DBDHBBOL_01259	1.65e-24	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DBDHBBOL_01260	2.5e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DBDHBBOL_01261	3.9e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBDHBBOL_01262	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBDHBBOL_01263	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
DBDHBBOL_01264	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DBDHBBOL_01265	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DBDHBBOL_01266	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
DBDHBBOL_01267	1.68e-191	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DBDHBBOL_01268	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DBDHBBOL_01270	1.32e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DBDHBBOL_01271	1.73e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
DBDHBBOL_01272	4.02e-190	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DBDHBBOL_01273	9.54e-117	cps3F	-	-	-	-	-	-	-
DBDHBBOL_01274	1.34e-39	-	-	-	M	-	-	-	biosynthesis protein
DBDHBBOL_01275	2.69e-278	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DBDHBBOL_01276	1.76e-256	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DBDHBBOL_01277	7.66e-87	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
DBDHBBOL_01278	1.29e-141	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DBDHBBOL_01279	1.87e-247	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
DBDHBBOL_01280	1.06e-116	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBDHBBOL_01281	1.23e-276	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
DBDHBBOL_01282	1.56e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_01283	1.86e-221	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DBDHBBOL_01284	8.64e-199	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DBDHBBOL_01285	1.78e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
DBDHBBOL_01286	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DBDHBBOL_01287	1.07e-59	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DBDHBBOL_01288	5.75e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
DBDHBBOL_01289	9.38e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DBDHBBOL_01290	1.2e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DBDHBBOL_01291	8.93e-290	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBDHBBOL_01292	3.41e-107	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DBDHBBOL_01293	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DBDHBBOL_01294	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
DBDHBBOL_01295	1.02e-20	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
DBDHBBOL_01297	1.92e-05	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
DBDHBBOL_01298	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
DBDHBBOL_01299	3.65e-291	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DBDHBBOL_01300	1.46e-149	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DBDHBBOL_01301	8.45e-218	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBDHBBOL_01302	5.56e-74	-	-	-	S	-	-	-	Flavodoxin
DBDHBBOL_01303	6.59e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
DBDHBBOL_01304	1.36e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
DBDHBBOL_01305	4.78e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DBDHBBOL_01306	2.58e-275	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
DBDHBBOL_01307	9.63e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DBDHBBOL_01308	4.54e-208	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DBDHBBOL_01309	9.77e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DBDHBBOL_01311	3.88e-189	-	-	-	H	-	-	-	geranyltranstransferase activity
DBDHBBOL_01312	1.28e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DBDHBBOL_01313	3.76e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DBDHBBOL_01314	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DBDHBBOL_01315	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBDHBBOL_01316	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
DBDHBBOL_01317	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DBDHBBOL_01318	1.35e-282	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DBDHBBOL_01319	5.2e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DBDHBBOL_01320	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DBDHBBOL_01321	2.78e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DBDHBBOL_01322	8.51e-243	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DBDHBBOL_01323	4.76e-262	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DBDHBBOL_01324	1.62e-173	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBDHBBOL_01325	9.6e-268	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
DBDHBBOL_01326	3.14e-267	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBDHBBOL_01328	3.47e-10	-	-	-	S	-	-	-	YSIRK type signal peptide
DBDHBBOL_01329	9.16e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
DBDHBBOL_01330	3.65e-80	-	-	-	-	-	-	-	-
DBDHBBOL_01331	1.26e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
DBDHBBOL_01332	1.16e-315	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DBDHBBOL_01333	5.31e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DBDHBBOL_01334	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DBDHBBOL_01335	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DBDHBBOL_01336	2.8e-148	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DBDHBBOL_01337	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DBDHBBOL_01338	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBDHBBOL_01339	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBDHBBOL_01340	2.4e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DBDHBBOL_01341	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
DBDHBBOL_01342	2.06e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DBDHBBOL_01343	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DBDHBBOL_01345	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DBDHBBOL_01346	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DBDHBBOL_01347	2.03e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DBDHBBOL_01348	2.36e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DBDHBBOL_01349	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DBDHBBOL_01350	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DBDHBBOL_01351	2.64e-284	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
DBDHBBOL_01353	9.41e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DBDHBBOL_01354	1.84e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBDHBBOL_01355	1.89e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DBDHBBOL_01356	3.97e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
DBDHBBOL_01357	5.6e-292	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
DBDHBBOL_01358	3.01e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBDHBBOL_01359	2.3e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DBDHBBOL_01360	5.43e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DBDHBBOL_01361	8.59e-221	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBDHBBOL_01362	4.29e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DBDHBBOL_01363	1.93e-189	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DBDHBBOL_01364	1.29e-282	-	-	-	K	-	-	-	DNA binding
DBDHBBOL_01365	2.83e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DBDHBBOL_01366	2.07e-207	-	-	-	K	-	-	-	LysR substrate binding domain
DBDHBBOL_01367	9.97e-167	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DBDHBBOL_01368	8.63e-189	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
DBDHBBOL_01369	5.93e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DBDHBBOL_01370	2.39e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DBDHBBOL_01371	2.13e-229	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DBDHBBOL_01372	3.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DBDHBBOL_01373	3.46e-213	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DBDHBBOL_01374	4.97e-74	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
DBDHBBOL_01376	8.04e-247	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DBDHBBOL_01377	9.48e-115	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DBDHBBOL_01379	4.07e-72	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
DBDHBBOL_01380	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
DBDHBBOL_01382	4.16e-129	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DBDHBBOL_01383	4.73e-51	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DBDHBBOL_01384	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DBDHBBOL_01385	1.82e-91	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DBDHBBOL_01386	2.77e-300	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DBDHBBOL_01388	5.95e-71	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
DBDHBBOL_01389	9.76e-82	-	-	-	S	-	-	-	YjbR
DBDHBBOL_01390	4.87e-156	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DBDHBBOL_01391	6.71e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
DBDHBBOL_01392	1.25e-144	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DBDHBBOL_01393	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DBDHBBOL_01394	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DBDHBBOL_01395	3.94e-20	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
DBDHBBOL_01396	2.28e-28	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
DBDHBBOL_01397	1.01e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DBDHBBOL_01399	2.16e-180	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
DBDHBBOL_01401	1.13e-242	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DBDHBBOL_01403	1.53e-94	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
DBDHBBOL_01404	1.3e-114	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
DBDHBBOL_01405	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DBDHBBOL_01406	1.75e-65	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
DBDHBBOL_01407	2.6e-114	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DBDHBBOL_01408	1.41e-144	-	-	-	Q	-	-	-	Methyltransferase domain
DBDHBBOL_01410	1.11e-132	-	-	-	S	-	-	-	CAAX protease self-immunity
DBDHBBOL_01411	1.07e-120	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBDHBBOL_01412	1.61e-14	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DBDHBBOL_01413	9.82e-103	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DBDHBBOL_01414	1.03e-34	rhaS4	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_01415	3.97e-130	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DBDHBBOL_01416	1.08e-273	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DBDHBBOL_01417	5.18e-135	-	-	-	-	-	-	-	-
DBDHBBOL_01418	8.08e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DBDHBBOL_01419	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DBDHBBOL_01421	1.78e-303	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DBDHBBOL_01422	4.68e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DBDHBBOL_01423	1.92e-283	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DBDHBBOL_01424	2.27e-223	-	-	-	-	-	-	-	-
DBDHBBOL_01425	2.16e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
DBDHBBOL_01426	9.35e-68	-	-	-	S	-	-	-	Cupredoxin-like domain
DBDHBBOL_01427	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DBDHBBOL_01428	1.63e-53	-	-	-	EGP	-	-	-	Major Facilitator
DBDHBBOL_01429	3.54e-95	-	-	-	EGP	-	-	-	Major Facilitator
DBDHBBOL_01430	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
DBDHBBOL_01431	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DBDHBBOL_01432	5.36e-07	-	-	-	-	-	-	-	-
DBDHBBOL_01433	4.32e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DBDHBBOL_01434	7.87e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DBDHBBOL_01435	1.14e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
DBDHBBOL_01436	4.03e-15	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DBDHBBOL_01437	1.51e-154	pnb	-	-	C	-	-	-	nitroreductase
DBDHBBOL_01438	1.79e-102	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
DBDHBBOL_01441	2.27e-114	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
DBDHBBOL_01442	2.29e-73	-	-	-	C	-	-	-	Flavodoxin
DBDHBBOL_01443	1.23e-44	-	-	-	S	-	-	-	Cyclophilin-like
DBDHBBOL_01444	7.68e-39	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DBDHBBOL_01445	2.33e-104	-	-	-	C	-	-	-	Aldo keto reductase
DBDHBBOL_01448	2.83e-122	-	-	-	C	-	-	-	aldo keto reductase
DBDHBBOL_01449	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
DBDHBBOL_01450	1.14e-71	gmT1	-	-	EG	-	-	-	EamA-like transporter family
DBDHBBOL_01451	2.99e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBDHBBOL_01453	9.62e-113	-	-	-	M	-	-	-	Iron Transport-associated domain
DBDHBBOL_01454	1.13e-130	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
DBDHBBOL_01455	7.99e-196	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
DBDHBBOL_01457	7.33e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
DBDHBBOL_01458	3.84e-94	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DBDHBBOL_01459	1.71e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DBDHBBOL_01460	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
DBDHBBOL_01461	1.91e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DBDHBBOL_01462	4.33e-132	-	-	-	NU	-	-	-	mannosyl-glycoprotein
DBDHBBOL_01463	6.27e-161	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DBDHBBOL_01464	3.41e-16	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DBDHBBOL_01465	8.5e-15	-	3.1.3.102, 3.1.3.104	-	S	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Haloacid dehalogenase-like hydrolase
DBDHBBOL_01466	1.31e-268	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DBDHBBOL_01467	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DBDHBBOL_01468	1.08e-39	-	-	-	S	-	-	-	Cytochrome B5
DBDHBBOL_01472	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DBDHBBOL_01473	1.28e-121	-	-	-	K	-	-	-	transcriptional regulator
DBDHBBOL_01474	4.51e-92	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DBDHBBOL_01475	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DBDHBBOL_01476	4.42e-71	-	-	-	S	-	-	-	MazG-like family
DBDHBBOL_01477	2.09e-136	-	-	-	I	-	-	-	PAP2 superfamily
DBDHBBOL_01478	1.18e-250	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DBDHBBOL_01479	4.28e-125	-	-	-	-	-	-	-	-
DBDHBBOL_01480	1.64e-283	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DBDHBBOL_01481	1.76e-206	-	-	-	V	-	-	-	Beta-lactamase enzyme family
DBDHBBOL_01482	0.0	potE	-	-	E	-	-	-	Amino Acid
DBDHBBOL_01484	2.17e-141	-	-	-	-	-	-	-	-
DBDHBBOL_01485	2.72e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
DBDHBBOL_01486	9.92e-211	-	-	-	K	-	-	-	LysR substrate binding domain
DBDHBBOL_01487	4.43e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DBDHBBOL_01488	3.48e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DBDHBBOL_01489	9.94e-29	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DBDHBBOL_01490	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DBDHBBOL_01491	1.56e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBDHBBOL_01492	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBDHBBOL_01493	3.27e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBDHBBOL_01494	1.17e-187	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DBDHBBOL_01495	1.9e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DBDHBBOL_01496	1.23e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBDHBBOL_01497	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DBDHBBOL_01498	2.09e-55	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DBDHBBOL_01499	7.15e-186	ylmH	-	-	S	-	-	-	S4 domain protein
DBDHBBOL_01500	1.46e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DBDHBBOL_01502	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBDHBBOL_01503	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DBDHBBOL_01504	5e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DBDHBBOL_01505	9.41e-09	-	-	-	-	-	-	-	-
DBDHBBOL_01506	1.33e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DBDHBBOL_01507	4.55e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DBDHBBOL_01508	4.67e-281	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DBDHBBOL_01509	0.0	-	-	-	S	-	-	-	amidohydrolase
DBDHBBOL_01510	3.1e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DBDHBBOL_01511	6.4e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DBDHBBOL_01512	1.09e-157	-	-	-	S	-	-	-	repeat protein
DBDHBBOL_01513	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DBDHBBOL_01514	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBDHBBOL_01515	2.39e-98	-	-	-	P	-	-	-	ArsC family
DBDHBBOL_01516	2.42e-238	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
DBDHBBOL_01517	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DBDHBBOL_01518	2.49e-97	-	-	-	-	-	-	-	-
DBDHBBOL_01519	4.09e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DBDHBBOL_01520	2.57e-64	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DBDHBBOL_01521	3.8e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DBDHBBOL_01522	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DBDHBBOL_01523	3.48e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DBDHBBOL_01524	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DBDHBBOL_01525	3.65e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DBDHBBOL_01526	3.56e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DBDHBBOL_01527	1.54e-249	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DBDHBBOL_01528	8.5e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DBDHBBOL_01529	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DBDHBBOL_01530	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DBDHBBOL_01531	1.34e-235	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DBDHBBOL_01532	7.12e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DBDHBBOL_01533	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DBDHBBOL_01534	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DBDHBBOL_01535	2.63e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DBDHBBOL_01536	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DBDHBBOL_01537	7.12e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DBDHBBOL_01538	7.63e-155	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
DBDHBBOL_01539	1.46e-148	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DBDHBBOL_01540	6.98e-71	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DBDHBBOL_01541	1.14e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBDHBBOL_01542	2.06e-198	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DBDHBBOL_01543	1.99e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DBDHBBOL_01544	1.03e-164	epsB	-	-	M	-	-	-	biosynthesis protein
DBDHBBOL_01545	2.06e-155	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DBDHBBOL_01546	7.14e-181	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DBDHBBOL_01547	4e-112	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
DBDHBBOL_01548	3.06e-99	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
DBDHBBOL_01549	1.69e-83	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DBDHBBOL_01550	7.18e-84	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
DBDHBBOL_01551	3.19e-33	epsJ	-	GT2	S	ko:K19425,ko:K19427	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
DBDHBBOL_01553	3.18e-48	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DBDHBBOL_01554	1.03e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
DBDHBBOL_01555	2.28e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DBDHBBOL_01556	1.81e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DBDHBBOL_01557	1.82e-183	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DBDHBBOL_01558	2.12e-180	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DBDHBBOL_01559	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBDHBBOL_01560	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DBDHBBOL_01561	3.74e-117	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBDHBBOL_01562	8.39e-47	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DBDHBBOL_01563	3.01e-41	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
DBDHBBOL_01564	5.72e-263	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DBDHBBOL_01565	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DBDHBBOL_01566	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DBDHBBOL_01567	1.46e-239	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DBDHBBOL_01568	8.79e-199	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DBDHBBOL_01569	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBDHBBOL_01570	1.54e-87	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DBDHBBOL_01571	5.63e-102	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DBDHBBOL_01572	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DBDHBBOL_01573	3.73e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DBDHBBOL_01574	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DBDHBBOL_01575	1.24e-162	-	-	-	F	-	-	-	glutamine amidotransferase
DBDHBBOL_01576	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DBDHBBOL_01577	8.03e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DBDHBBOL_01578	4.96e-247	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DBDHBBOL_01579	2.06e-188	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
DBDHBBOL_01580	7.6e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
DBDHBBOL_01581	5.3e-214	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
DBDHBBOL_01582	3.61e-315	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
DBDHBBOL_01583	4.18e-198	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DBDHBBOL_01584	4.49e-31	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DBDHBBOL_01585	1.13e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DBDHBBOL_01586	1.75e-172	-	-	-	IQ	-	-	-	KR domain
DBDHBBOL_01587	1.5e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DBDHBBOL_01588	4.83e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01589	8.91e-145	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
DBDHBBOL_01590	9.32e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
DBDHBBOL_01592	7.57e-264	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DBDHBBOL_01593	7.31e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DBDHBBOL_01594	4.12e-108	-	-	-	K	-	-	-	Transcriptional regulator
DBDHBBOL_01595	3.64e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DBDHBBOL_01596	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBDHBBOL_01597	4.23e-76	-	-	-	-	-	-	-	-
DBDHBBOL_01598	1.23e-173	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DBDHBBOL_01599	2.39e-227	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DBDHBBOL_01600	9.74e-72	-	-	-	-	-	-	-	-
DBDHBBOL_01602	3.36e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DBDHBBOL_01603	3.22e-118	-	-	-	S	-	-	-	integral membrane protein
DBDHBBOL_01604	1.89e-86	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBDHBBOL_01605	4.49e-230	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
DBDHBBOL_01607	1.19e-51	-	-	-	S	-	-	-	Phage integrase family
DBDHBBOL_01609	1.3e-99	-	-	-	-	-	-	-	-
DBDHBBOL_01610	1.07e-80	-	-	-	-	-	-	-	-
DBDHBBOL_01612	5.23e-147	-	-	-	-	-	-	-	-
DBDHBBOL_01614	2.34e-24	-	-	-	L	-	-	-	nuclease
DBDHBBOL_01616	2.13e-31	-	-	-	E	-	-	-	Zn peptidase
DBDHBBOL_01617	2.93e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DBDHBBOL_01621	1.45e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
DBDHBBOL_01622	3.32e-143	-	-	-	S	-	-	-	DNA binding
DBDHBBOL_01631	8.44e-33	-	-	-	S	-	-	-	Erf family
DBDHBBOL_01632	2.72e-46	-	-	-	S	-	-	-	Single-strand binding protein family
DBDHBBOL_01633	2.75e-91	-	-	-	S	-	-	-	Putative HNHc nuclease
DBDHBBOL_01634	8.38e-136	-	-	-	S	-	-	-	calcium ion binding
DBDHBBOL_01635	2.01e-51	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DBDHBBOL_01638	1.27e-54	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
DBDHBBOL_01645	1.81e-68	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
DBDHBBOL_01646	6.64e-44	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
DBDHBBOL_01647	7.13e-42	-	-	-	L	-	-	-	HNH nucleases
DBDHBBOL_01648	2.73e-136	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBDHBBOL_01649	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DBDHBBOL_01650	1e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DBDHBBOL_01651	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DBDHBBOL_01652	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBDHBBOL_01653	1.81e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DBDHBBOL_01654	1.27e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DBDHBBOL_01655	1.5e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DBDHBBOL_01656	9.86e-102	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
DBDHBBOL_01657	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DBDHBBOL_01658	9.48e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
DBDHBBOL_01659	1.2e-21	-	-	-	K	-	-	-	transcriptional regulator
DBDHBBOL_01660	1.42e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DBDHBBOL_01661	1.66e-66	-	-	-	K	-	-	-	TRANSCRIPTIONal
DBDHBBOL_01662	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBDHBBOL_01663	1.46e-236	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DBDHBBOL_01664	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBDHBBOL_01665	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DBDHBBOL_01666	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBDHBBOL_01667	9.18e-232	camS	-	-	S	-	-	-	sex pheromone
DBDHBBOL_01668	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DBDHBBOL_01669	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DBDHBBOL_01670	1.97e-275	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DBDHBBOL_01671	9.17e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DBDHBBOL_01672	1.92e-141	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DBDHBBOL_01673	1.43e-176	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
DBDHBBOL_01674	2.23e-258	-	-	-	S	-	-	-	interspecies interaction between organisms
DBDHBBOL_01675	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DBDHBBOL_01676	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DBDHBBOL_01677	2.6e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DBDHBBOL_01678	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBDHBBOL_01679	6.6e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBDHBBOL_01680	2.91e-191	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBDHBBOL_01681	1.7e-79	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DBDHBBOL_01682	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBDHBBOL_01683	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DBDHBBOL_01684	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DBDHBBOL_01685	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DBDHBBOL_01686	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBDHBBOL_01687	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DBDHBBOL_01688	1.92e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DBDHBBOL_01689	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DBDHBBOL_01690	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DBDHBBOL_01691	2.08e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DBDHBBOL_01692	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DBDHBBOL_01693	4.83e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DBDHBBOL_01694	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DBDHBBOL_01695	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBDHBBOL_01696	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DBDHBBOL_01697	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DBDHBBOL_01698	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DBDHBBOL_01699	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DBDHBBOL_01700	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DBDHBBOL_01701	2.29e-97	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBDHBBOL_01702	2.49e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DBDHBBOL_01703	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBDHBBOL_01704	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBDHBBOL_01705	1.58e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DBDHBBOL_01706	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DBDHBBOL_01707	3.03e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DBDHBBOL_01708	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DBDHBBOL_01709	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DBDHBBOL_01710	4.38e-82	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
DBDHBBOL_01711	2.04e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DBDHBBOL_01712	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBDHBBOL_01713	3.41e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DBDHBBOL_01714	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DBDHBBOL_01715	2.5e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
DBDHBBOL_01716	5.84e-273	-	-	-	-	-	-	-	-
DBDHBBOL_01717	8.36e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DBDHBBOL_01718	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBDHBBOL_01719	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBDHBBOL_01720	5.75e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DBDHBBOL_01721	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DBDHBBOL_01722	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DBDHBBOL_01723	8.08e-147	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
DBDHBBOL_01724	1.84e-225	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DBDHBBOL_01725	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DBDHBBOL_01726	1.72e-262	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DBDHBBOL_01727	1.81e-94	-	-	-	F	-	-	-	Nudix hydrolase
DBDHBBOL_01728	3.76e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DBDHBBOL_01729	7.28e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DBDHBBOL_01730	2.5e-09	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DBDHBBOL_01731	9.19e-213	-	-	-	-	-	-	-	-
DBDHBBOL_01732	9.3e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DBDHBBOL_01733	2.01e-120	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
DBDHBBOL_01734	2.79e-310	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DBDHBBOL_01735	1.59e-212	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DBDHBBOL_01736	1.04e-224	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DBDHBBOL_01737	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DBDHBBOL_01738	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DBDHBBOL_01739	1.95e-140	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DBDHBBOL_01740	5.23e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DBDHBBOL_01741	2.39e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DBDHBBOL_01742	1.9e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DBDHBBOL_01743	1.45e-142	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DBDHBBOL_01744	9.57e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBDHBBOL_01745	8.4e-201	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DBDHBBOL_01750	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
DBDHBBOL_01751	1.18e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DBDHBBOL_01752	1.49e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DBDHBBOL_01753	1.1e-246	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DBDHBBOL_01754	8.48e-177	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DBDHBBOL_01755	8.35e-109	-	-	-	M	-	-	-	PFAM NLP P60 protein
DBDHBBOL_01756	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DBDHBBOL_01757	2.94e-167	-	-	-	-	-	-	-	-
DBDHBBOL_01758	6.64e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DBDHBBOL_01759	2.1e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DBDHBBOL_01760	2.11e-88	-	-	-	-	-	-	-	-
DBDHBBOL_01761	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DBDHBBOL_01762	1.02e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DBDHBBOL_01763	9.46e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DBDHBBOL_01764	3.89e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DBDHBBOL_01765	2.54e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBDHBBOL_01766	1.1e-105	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DBDHBBOL_01767	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DBDHBBOL_01768	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
DBDHBBOL_01769	1.58e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DBDHBBOL_01770	3.32e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DBDHBBOL_01771	9.71e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01772	3.05e-99	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DBDHBBOL_01773	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DBDHBBOL_01774	1.97e-276	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DBDHBBOL_01775	4.28e-159	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DBDHBBOL_01776	2.92e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DBDHBBOL_01778	1.35e-237	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DBDHBBOL_01780	1.27e-284	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DBDHBBOL_01781	6.09e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01782	9.1e-317	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DBDHBBOL_01783	1.04e-270	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
DBDHBBOL_01784	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DBDHBBOL_01785	2.48e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DBDHBBOL_01786	3.3e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DBDHBBOL_01787	7.2e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DBDHBBOL_01788	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DBDHBBOL_01789	2.13e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DBDHBBOL_01790	2.28e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DBDHBBOL_01791	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DBDHBBOL_01792	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DBDHBBOL_01793	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DBDHBBOL_01794	1.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBDHBBOL_01795	2.56e-184	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DBDHBBOL_01796	8.98e-196	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DBDHBBOL_01797	2.06e-279	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
DBDHBBOL_01799	3.89e-215	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
DBDHBBOL_01800	1.82e-41	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBDHBBOL_01801	3.96e-250	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DBDHBBOL_01802	6.95e-51	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DBDHBBOL_01803	1.25e-90	gntR	-	-	K	-	-	-	rpiR family
DBDHBBOL_01804	2.33e-125	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DBDHBBOL_01806	3.55e-123	-	-	-	-	-	-	-	-
DBDHBBOL_01807	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DBDHBBOL_01808	1.29e-231	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DBDHBBOL_01810	1.49e-145	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
DBDHBBOL_01811	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
DBDHBBOL_01812	2.02e-66	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DBDHBBOL_01813	3.54e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DBDHBBOL_01814	3.83e-55	-	-	-	S	-	-	-	Protein conserved in bacteria
DBDHBBOL_01815	1.5e-123	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
DBDHBBOL_01816	1.02e-191	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
DBDHBBOL_01817	2.24e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBDHBBOL_01818	2.33e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
DBDHBBOL_01819	9.84e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBDHBBOL_01820	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DBDHBBOL_01821	4.54e-171	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
DBDHBBOL_01822	2.42e-43	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
DBDHBBOL_01823	3.95e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DBDHBBOL_01824	4.53e-221	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DBDHBBOL_01825	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
DBDHBBOL_01826	2.4e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DBDHBBOL_01828	4.45e-73	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
DBDHBBOL_01829	1.93e-144	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
DBDHBBOL_01830	5.14e-155	-	-	-	Q	-	-	-	Methyltransferase domain
DBDHBBOL_01831	3.84e-88	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DBDHBBOL_01832	2.5e-72	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
DBDHBBOL_01833	3.07e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DBDHBBOL_01834	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DBDHBBOL_01835	3.92e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DBDHBBOL_01836	5.23e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DBDHBBOL_01837	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DBDHBBOL_01838	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DBDHBBOL_01839	1.58e-203	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DBDHBBOL_01840	1.75e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DBDHBBOL_01841	9.6e-317	ymfH	-	-	S	-	-	-	Peptidase M16
DBDHBBOL_01842	4.68e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
DBDHBBOL_01843	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBDHBBOL_01844	4.07e-287	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DBDHBBOL_01845	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DBDHBBOL_01846	4.61e-298	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DBDHBBOL_01847	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DBDHBBOL_01848	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
DBDHBBOL_01849	1.29e-255	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
DBDHBBOL_01850	8.88e-242	arcT	-	-	E	-	-	-	Dipeptidase
DBDHBBOL_01851	8.66e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DBDHBBOL_01852	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
DBDHBBOL_01853	4.26e-130	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
DBDHBBOL_01854	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBDHBBOL_01855	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DBDHBBOL_01856	1.7e-263	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DBDHBBOL_01857	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DBDHBBOL_01858	3.28e-165	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DBDHBBOL_01859	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBDHBBOL_01860	1.21e-212	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DBDHBBOL_01861	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBDHBBOL_01862	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DBDHBBOL_01863	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DBDHBBOL_01864	2.88e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DBDHBBOL_01865	3.72e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DBDHBBOL_01866	6.38e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DBDHBBOL_01867	8.84e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DBDHBBOL_01868	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DBDHBBOL_01869	1.8e-164	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DBDHBBOL_01870	8.71e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBDHBBOL_01871	5.38e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DBDHBBOL_01872	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBDHBBOL_01873	1.82e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBDHBBOL_01874	1.9e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DBDHBBOL_01875	4.19e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DBDHBBOL_01877	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DBDHBBOL_01878	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DBDHBBOL_01879	6.61e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DBDHBBOL_01880	4.66e-199	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DBDHBBOL_01881	6.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DBDHBBOL_01882	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DBDHBBOL_01883	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DBDHBBOL_01884	4.67e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBDHBBOL_01885	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DBDHBBOL_01886	1.7e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DBDHBBOL_01887	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DBDHBBOL_01888	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DBDHBBOL_01889	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DBDHBBOL_01890	1.24e-146	-	-	-	K	-	-	-	Transcriptional regulator