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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CPLHMICO_00001	3.97e-162	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
CPLHMICO_00002	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CPLHMICO_00003	7.57e-10	-	-	-	Q	-	-	-	Methyltransferase domain
CPLHMICO_00004	4.5e-60	ybaJ	-	-	Q	-	-	-	Hypothetical methyltransferase
CPLHMICO_00005	9.29e-57	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
CPLHMICO_00006	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_00007	2.41e-242	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CPLHMICO_00008	1.71e-09	carA	6.3.5.5	-	F	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPLHMICO_00010	1.28e-277	-	-	-	V	-	-	-	MATE efflux family protein
CPLHMICO_00011	1.18e-94	-	-	-	K	-	-	-	3.5.2 Transcription regulation
CPLHMICO_00012	2.14e-41	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CPLHMICO_00013	1.05e-137	-	-	-	L	-	-	-	Integrase
CPLHMICO_00014	3.6e-136	cylB	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
CPLHMICO_00015	1.01e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CPLHMICO_00016	2.73e-98	-	-	-	-	-	-	-	-
CPLHMICO_00017	2.37e-91	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
CPLHMICO_00019	2.02e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00020	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CPLHMICO_00021	2.04e-17	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
CPLHMICO_00023	1.22e-107	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CPLHMICO_00024	1.15e-244	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CPLHMICO_00026	6.85e-137	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CPLHMICO_00027	4.73e-65	-	-	-	S	-	-	-	SLAP domain
CPLHMICO_00028	1.68e-70	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
CPLHMICO_00029	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
CPLHMICO_00030	1.2e-140	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CPLHMICO_00031	3.7e-270	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00032	1.57e-166	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CPLHMICO_00033	2.38e-171	-	-	-	-	-	-	-	-
CPLHMICO_00034	4.3e-48	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
CPLHMICO_00035	1.33e-53	-	-	-	S	-	-	-	Oxidoreductase
CPLHMICO_00036	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CPLHMICO_00037	0.0	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
CPLHMICO_00038	3.68e-260	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CPLHMICO_00039	6.35e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
CPLHMICO_00040	1.23e-39	-	-	-	-	-	-	-	-
CPLHMICO_00041	1.47e-175	-	-	-	-	-	-	-	-
CPLHMICO_00042	2.42e-96	-	-	-	-	-	-	-	-
CPLHMICO_00043	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CPLHMICO_00044	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CPLHMICO_00045	4.39e-82	-	-	-	O	-	-	-	Glutaredoxin-related protein
CPLHMICO_00046	2.77e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
CPLHMICO_00047	5.06e-62	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
CPLHMICO_00048	1.61e-44	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CPLHMICO_00049	2.52e-182	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPLHMICO_00050	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
CPLHMICO_00051	5.46e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CPLHMICO_00052	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CPLHMICO_00053	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CPLHMICO_00054	3e-108	-	-	-	-	-	-	-	-
CPLHMICO_00055	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00056	4.49e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_00057	1.59e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_00058	2.39e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CPLHMICO_00059	4.69e-210	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
CPLHMICO_00061	3.83e-109	usp5	-	-	T	-	-	-	universal stress protein
CPLHMICO_00062	3.05e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CPLHMICO_00063	1.09e-109	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CPLHMICO_00064	2.59e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
CPLHMICO_00065	6.17e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPLHMICO_00066	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
CPLHMICO_00067	2.86e-81	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_00068	2.03e-127	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_00069	1.46e-109	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
CPLHMICO_00070	3.11e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CPLHMICO_00071	1.98e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CPLHMICO_00072	6.42e-243	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CPLHMICO_00074	1.41e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CPLHMICO_00075	3.76e-265	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
CPLHMICO_00076	1.69e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
CPLHMICO_00077	1.67e-185	-	-	-	-	-	-	-	-
CPLHMICO_00078	2.31e-162	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CPLHMICO_00079	2.95e-237	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPLHMICO_00080	1.92e-162	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CPLHMICO_00081	2.85e-205	epsV	-	-	S	-	-	-	glycosyl transferase family 2
CPLHMICO_00082	5.66e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CPLHMICO_00083	2.48e-176	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPLHMICO_00084	4.47e-229	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CPLHMICO_00085	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPLHMICO_00086	2.38e-104	-	-	-	-	-	-	-	-
CPLHMICO_00087	3.56e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
CPLHMICO_00088	7.87e-88	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CPLHMICO_00089	6.22e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CPLHMICO_00090	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_00091	2.81e-181	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00093	5.52e-151	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_00094	2.78e-222	-	-	-	L	-	-	-	HNH nucleases
CPLHMICO_00095	1.37e-21	-	-	-	-	-	-	-	-
CPLHMICO_00096	1.46e-261	ysdE	-	-	P	-	-	-	Citrate transporter
CPLHMICO_00097	1.67e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CPLHMICO_00098	1.15e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CPLHMICO_00099	1.69e-193	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CPLHMICO_00100	4.84e-284	-	-	-	S	ko:K09136	-	ko00000,ko03009	ATP diphosphatase activity
CPLHMICO_00102	3.96e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CPLHMICO_00103	5.47e-156	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CPLHMICO_00104	4.6e-220	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CPLHMICO_00105	1.06e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CPLHMICO_00106	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_00107	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00108	8.61e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CPLHMICO_00110	3.47e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CPLHMICO_00111	2.7e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00113	6.96e-30	-	-	-	-	-	-	-	-
CPLHMICO_00114	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
CPLHMICO_00115	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K11085,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CPLHMICO_00116	3.6e-35	-	-	-	-	-	-	-	-
CPLHMICO_00118	1.91e-243	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CPLHMICO_00119	6.57e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CPLHMICO_00120	1.14e-134	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_00121	1.72e-91	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_00123	6.54e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
CPLHMICO_00125	4.46e-90	-	-	-	-	-	-	-	-
CPLHMICO_00126	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
CPLHMICO_00127	6.23e-290	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
CPLHMICO_00128	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CPLHMICO_00129	6.68e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CPLHMICO_00130	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CPLHMICO_00131	1.61e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CPLHMICO_00132	1.79e-126	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CPLHMICO_00133	1.21e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CPLHMICO_00134	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPLHMICO_00135	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPLHMICO_00136	2.02e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CPLHMICO_00137	2.22e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CPLHMICO_00138	1.97e-256	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CPLHMICO_00139	1.7e-313	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CPLHMICO_00140	1.48e-82	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CPLHMICO_00141	2.21e-196	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CPLHMICO_00142	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CPLHMICO_00143	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CPLHMICO_00144	4.78e-79	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CPLHMICO_00145	7.16e-25	steT	-	-	E	ko:K03294	-	ko00000	amino acid
CPLHMICO_00146	2.29e-297	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
CPLHMICO_00147	3.63e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CPLHMICO_00148	1.29e-154	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CPLHMICO_00149	8.4e-28	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00150	1.76e-77	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00153	7.38e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
CPLHMICO_00154	1.9e-156	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00155	1.73e-21	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00156	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_00157	9.35e-202	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPLHMICO_00158	3.19e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPLHMICO_00159	2.78e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CPLHMICO_00160	1.33e-227	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CPLHMICO_00161	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CPLHMICO_00162	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
CPLHMICO_00163	6.11e-96	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CPLHMICO_00164	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CPLHMICO_00165	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CPLHMICO_00166	4.21e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CPLHMICO_00167	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CPLHMICO_00168	3.2e-83	-	-	-	-	-	-	-	-
CPLHMICO_00169	3.79e-291	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CPLHMICO_00170	1.6e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CPLHMICO_00171	4.88e-262	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CPLHMICO_00172	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CPLHMICO_00173	5.02e-52	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
CPLHMICO_00174	7.29e-84	-	-	-	S	-	-	-	HicB family
CPLHMICO_00175	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
CPLHMICO_00176	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_00177	1.25e-180	-	-	-	K	-	-	-	Transcriptional regulator
CPLHMICO_00178	4.11e-213	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CPLHMICO_00179	7.58e-146	-	-	-	F	-	-	-	Phosphorylase superfamily
CPLHMICO_00180	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CPLHMICO_00181	6.97e-216	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CPLHMICO_00182	3.57e-60	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CPLHMICO_00183	2.8e-196	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CPLHMICO_00184	8.29e-223	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
CPLHMICO_00185	1.75e-11	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
CPLHMICO_00186	7.43e-68	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
CPLHMICO_00187	8.35e-06	tyrA	1.3.1.12, 5.4.99.5	-	E	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	T-protein
CPLHMICO_00188	4.05e-98	-	-	-	K	-	-	-	DNA-binding transcription factor activity
CPLHMICO_00189	2.51e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
CPLHMICO_00190	5.66e-119	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_00191	7.39e-103	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CPLHMICO_00192	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CPLHMICO_00194	2.58e-11	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
CPLHMICO_00195	1.47e-288	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CPLHMICO_00196	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CPLHMICO_00199	6.81e-253	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
CPLHMICO_00200	1.58e-16	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
CPLHMICO_00201	3.6e-284	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CPLHMICO_00204	2.79e-62	-	-	-	-	-	-	-	-
CPLHMICO_00205	0.0	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
CPLHMICO_00206	4.74e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CPLHMICO_00207	4.15e-10	-	-	-	K	-	-	-	Helix-turn-helix domain
CPLHMICO_00209	8.18e-208	-	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
CPLHMICO_00210	5.68e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CPLHMICO_00211	3.77e-08	-	-	-	-	-	-	-	-
CPLHMICO_00212	1.35e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
CPLHMICO_00213	5.13e-214	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CPLHMICO_00214	9.98e-179	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
CPLHMICO_00215	2.72e-238	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CPLHMICO_00216	1.6e-115	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
CPLHMICO_00217	7.18e-57	-	-	-	-	-	-	-	-
CPLHMICO_00218	1.48e-155	-	-	-	-	-	-	-	-
CPLHMICO_00219	2.49e-16	-	-	-	-	-	-	-	-
CPLHMICO_00220	1.92e-161	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
CPLHMICO_00221	9.22e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CPLHMICO_00222	3.16e-93	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CPLHMICO_00223	9.57e-106	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
CPLHMICO_00224	1.19e-155	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00225	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CPLHMICO_00226	3.47e-82	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CPLHMICO_00229	1.13e-223	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CPLHMICO_00230	9.09e-314	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CPLHMICO_00231	7.14e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CPLHMICO_00232	2.35e-210	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
CPLHMICO_00233	3.79e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CPLHMICO_00234	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPLHMICO_00235	1.02e-196	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CPLHMICO_00236	1.88e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPLHMICO_00237	4.39e-210	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CPLHMICO_00238	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CPLHMICO_00239	3.72e-200	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CPLHMICO_00240	1.97e-151	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CPLHMICO_00241	1.19e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CPLHMICO_00242	5.15e-216	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CPLHMICO_00246	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CPLHMICO_00247	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00248	1.79e-212	-	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00249	6.72e-204	-	-	-	-	-	-	-	-
CPLHMICO_00250	1.52e-129	-	-	-	I	-	-	-	PAP2 superfamily
CPLHMICO_00251	1.06e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CPLHMICO_00252	9.3e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CPLHMICO_00253	9.52e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
CPLHMICO_00254	7.8e-257	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
CPLHMICO_00255	4.87e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
CPLHMICO_00256	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00257	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CPLHMICO_00258	5.95e-203	lysR5	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00259	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
CPLHMICO_00260	1.09e-36	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00261	2.47e-88	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00262	1.19e-19	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00263	8.77e-245	-	-	-	S	-	-	-	AI-2E family transporter
CPLHMICO_00264	1.39e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
CPLHMICO_00265	7.41e-198	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CPLHMICO_00266	5.47e-66	-	-	-	K	-	-	-	DNA-binding transcription factor activity
CPLHMICO_00267	2.82e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPLHMICO_00268	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CPLHMICO_00269	7.92e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
CPLHMICO_00270	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CPLHMICO_00271	5.57e-237	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CPLHMICO_00272	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CPLHMICO_00273	1.04e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPLHMICO_00274	1.86e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CPLHMICO_00275	6.61e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CPLHMICO_00276	1.1e-75	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CPLHMICO_00277	7.38e-86	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
CPLHMICO_00278	4.01e-192	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CPLHMICO_00279	3.87e-89	-	-	-	T	-	-	-	domain protein
CPLHMICO_00280	4.69e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
CPLHMICO_00281	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPLHMICO_00282	1.09e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
CPLHMICO_00283	8.97e-66	-	-	-	-	-	-	-	-
CPLHMICO_00284	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CPLHMICO_00286	4.68e-234	-	-	-	S	-	-	-	AAA domain
CPLHMICO_00287	8.76e-104	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CPLHMICO_00288	4.33e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CPLHMICO_00289	8.57e-41	-	-	-	-	-	-	-	-
CPLHMICO_00290	2.88e-39	-	-	-	-	-	-	-	-
CPLHMICO_00291	5.92e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
CPLHMICO_00292	1.22e-65	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CPLHMICO_00293	7.23e-73	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CPLHMICO_00294	2.77e-140	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
CPLHMICO_00295	5.51e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CPLHMICO_00296	2.03e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
CPLHMICO_00297	5.86e-133	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
CPLHMICO_00298	2.21e-177	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CPLHMICO_00299	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CPLHMICO_00300	6.17e-62	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CPLHMICO_00301	7.22e-215	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CPLHMICO_00302	3.01e-11	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
CPLHMICO_00303	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
CPLHMICO_00304	7.1e-197	-	-	-	D	-	-	-	nuclear chromosome segregation
CPLHMICO_00305	7.13e-128	-	-	-	M	-	-	-	LysM domain protein
CPLHMICO_00307	3.72e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CPLHMICO_00308	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
CPLHMICO_00310	8.22e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CPLHMICO_00311	5.29e-77	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CPLHMICO_00312	1.14e-24	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
CPLHMICO_00313	3.16e-61	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CPLHMICO_00315	6.29e-71	-	-	-	S	-	-	-	Alpha beta hydrolase
CPLHMICO_00316	4.73e-206	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
CPLHMICO_00317	1.13e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CPLHMICO_00318	6.68e-32	-	-	-	-	-	-	-	-
CPLHMICO_00319	1.36e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CPLHMICO_00320	5.49e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPLHMICO_00321	1.38e-156	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CPLHMICO_00322	8.58e-103	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CPLHMICO_00323	6.18e-184	-	-	-	S	-	-	-	Peptidase family M23
CPLHMICO_00324	1.52e-70	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPLHMICO_00325	6.76e-47	-	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	PFAM Metal binding domain of Ada
CPLHMICO_00328	3.32e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CPLHMICO_00329	1.31e-79	-	-	-	-	-	-	-	-
CPLHMICO_00330	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
CPLHMICO_00331	3.18e-295	-	-	-	S	-	-	-	TIGR02687 family
CPLHMICO_00332	0.0	-	-	-	V	-	-	-	restriction
CPLHMICO_00333	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
CPLHMICO_00334	3.43e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
CPLHMICO_00335	1.59e-74	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
CPLHMICO_00336	1.05e-251	-	-	-	S	-	-	-	Protein of unknown function DUF262
CPLHMICO_00337	4.18e-38	-	-	-	-	-	-	-	-
CPLHMICO_00338	4.66e-93	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
CPLHMICO_00339	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CPLHMICO_00340	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CPLHMICO_00341	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CPLHMICO_00342	2.02e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
CPLHMICO_00343	4.99e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CPLHMICO_00344	4.5e-259	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CPLHMICO_00345	2.27e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CPLHMICO_00346	2.02e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CPLHMICO_00347	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CPLHMICO_00348	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CPLHMICO_00349	1.1e-144	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CPLHMICO_00350	3.97e-38	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CPLHMICO_00351	2.51e-235	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CPLHMICO_00352	1.05e-68	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
CPLHMICO_00353	9.54e-55	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00354	6.37e-08	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00355	1.25e-45	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
CPLHMICO_00356	1.6e-12	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CPLHMICO_00357	1.11e-194	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_00358	1.21e-134	-	-	-	-	-	-	-	-
CPLHMICO_00359	4.56e-243	-	-	-	T	-	-	-	diguanylate cyclase
CPLHMICO_00360	1.91e-264	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CPLHMICO_00361	1.29e-86	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CPLHMICO_00363	1.43e-135	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
CPLHMICO_00364	1.73e-173	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CPLHMICO_00365	6.38e-192	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CPLHMICO_00366	7.4e-178	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CPLHMICO_00367	8.7e-53	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
CPLHMICO_00368	5.43e-133	M1-740	-	-	I	-	-	-	NUDIX domain
CPLHMICO_00369	6.65e-236	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
CPLHMICO_00370	1.11e-156	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CPLHMICO_00372	9.61e-106	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
CPLHMICO_00373	2.71e-28	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CPLHMICO_00374	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CPLHMICO_00375	2.5e-161	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
CPLHMICO_00376	1.98e-147	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CPLHMICO_00377	9.06e-182	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CPLHMICO_00378	4.17e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CPLHMICO_00379	5.27e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CPLHMICO_00380	8.71e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CPLHMICO_00383	9.19e-76	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CPLHMICO_00384	2.26e-49	-	-	-	-	-	-	-	-
CPLHMICO_00385	1.8e-113	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00386	3.04e-126	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00391	2.25e-206	-	-	-	J	-	-	-	Methyltransferase
CPLHMICO_00392	8.57e-101	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
CPLHMICO_00393	2.11e-231	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
CPLHMICO_00400	1.57e-51	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CPLHMICO_00401	5.82e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CPLHMICO_00402	1.57e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CPLHMICO_00403	1.43e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CPLHMICO_00404	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CPLHMICO_00405	2.3e-158	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CPLHMICO_00406	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CPLHMICO_00407	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CPLHMICO_00408	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CPLHMICO_00409	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CPLHMICO_00410	2.34e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CPLHMICO_00411	1.02e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CPLHMICO_00412	5.99e-71	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CPLHMICO_00413	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CPLHMICO_00414	1.35e-261	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CPLHMICO_00415	7.71e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CPLHMICO_00416	4.29e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CPLHMICO_00417	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPLHMICO_00418	3.09e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CPLHMICO_00419	1.09e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPLHMICO_00420	1.92e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CPLHMICO_00421	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CPLHMICO_00422	3.78e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CPLHMICO_00423	1.01e-87	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CPLHMICO_00424	2.08e-146	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CPLHMICO_00425	5.67e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CPLHMICO_00426	1.1e-27	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CPLHMICO_00427	4.86e-59	-	-	-	-	-	-	-	-
CPLHMICO_00428	4.79e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CPLHMICO_00429	2.14e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CPLHMICO_00430	2.89e-77	-	-	-	-	-	-	-	-
CPLHMICO_00431	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CPLHMICO_00432	7.82e-114	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CPLHMICO_00433	5.46e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CPLHMICO_00434	4.03e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CPLHMICO_00435	5.45e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CPLHMICO_00436	1.46e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CPLHMICO_00437	2.44e-92	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
CPLHMICO_00438	6.94e-33	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
CPLHMICO_00439	1.01e-26	-	-	-	S	-	-	-	YjbR
CPLHMICO_00440	8.4e-85	-	-	-	S	-	-	-	YjbR
CPLHMICO_00441	2.58e-179	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
CPLHMICO_00442	1.27e-139	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CPLHMICO_00443	2.57e-168	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
CPLHMICO_00444	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
CPLHMICO_00445	3.67e-11	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
CPLHMICO_00447	1.11e-33	-	-	-	-	-	-	-	-
CPLHMICO_00448	3.18e-201	-	-	-	V	-	-	-	LD-carboxypeptidase
CPLHMICO_00449	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CPLHMICO_00450	8.58e-223	-	-	-	-	-	-	-	-
CPLHMICO_00451	3.04e-177	-	-	-	-	-	-	-	-
CPLHMICO_00452	4.3e-36	-	-	-	-	-	-	-	-
CPLHMICO_00453	2.74e-145	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CPLHMICO_00454	5.87e-177	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
CPLHMICO_00455	1.42e-92	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
CPLHMICO_00456	1.36e-46	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CPLHMICO_00457	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CPLHMICO_00458	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CPLHMICO_00459	1.73e-218	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00460	4.87e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
CPLHMICO_00461	1.39e-122	-	-	-	GM	-	-	-	NmrA-like family
CPLHMICO_00462	4.36e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
CPLHMICO_00463	8.63e-198	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CPLHMICO_00464	1.12e-63	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CPLHMICO_00465	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CPLHMICO_00466	2.08e-105	-	-	-	K	-	-	-	GNAT family
CPLHMICO_00467	6.47e-110	-	-	-	-	-	-	-	-
CPLHMICO_00468	1.37e-08	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
CPLHMICO_00469	7.21e-39	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
CPLHMICO_00470	2.04e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
CPLHMICO_00471	5.13e-84	-	-	-	S	-	-	-	Domain of unknown function DUF1828
CPLHMICO_00472	7.46e-279	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CPLHMICO_00473	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CPLHMICO_00474	2.1e-206	ynbB	-	-	P	-	-	-	aluminum resistance
CPLHMICO_00475	4.4e-217	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPLHMICO_00476	8.9e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CPLHMICO_00477	2.98e-45	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CPLHMICO_00478	6.54e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
CPLHMICO_00479	2.26e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CPLHMICO_00480	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CPLHMICO_00481	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CPLHMICO_00482	0.0	-	-	-	S	-	-	-	membrane
CPLHMICO_00483	2.55e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CPLHMICO_00484	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CPLHMICO_00485	1.96e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPLHMICO_00486	8.09e-80	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CPLHMICO_00487	1.04e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPLHMICO_00488	2.2e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CPLHMICO_00489	1.93e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CPLHMICO_00490	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CPLHMICO_00491	1.96e-164	csrR	-	-	K	-	-	-	response regulator
CPLHMICO_00492	2.09e-130	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CPLHMICO_00493	5.85e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CPLHMICO_00494	1.46e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CPLHMICO_00495	3.91e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CPLHMICO_00496	1.58e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CPLHMICO_00497	1.16e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CPLHMICO_00498	2.91e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CPLHMICO_00499	1.37e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CPLHMICO_00500	3.99e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CPLHMICO_00501	1.09e-90	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
CPLHMICO_00502	1.11e-232	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
CPLHMICO_00503	2.29e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
CPLHMICO_00504	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
CPLHMICO_00505	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPLHMICO_00506	4.07e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CPLHMICO_00507	5.47e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
CPLHMICO_00508	1.57e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPLHMICO_00509	1.03e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CPLHMICO_00510	2.96e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CPLHMICO_00511	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPLHMICO_00512	2.79e-48	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_00513	2.12e-146	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_00514	3.97e-19	-	-	-	EGP	-	-	-	Major facilitator Superfamily
CPLHMICO_00516	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CPLHMICO_00517	1.7e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CPLHMICO_00518	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
CPLHMICO_00519	1.64e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CPLHMICO_00520	7.71e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CPLHMICO_00521	1.43e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00522	2.77e-103	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
CPLHMICO_00523	1.4e-71	-	-	-	-	-	-	-	-
CPLHMICO_00524	2.87e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CPLHMICO_00525	2.5e-173	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CPLHMICO_00526	9.14e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPLHMICO_00527	8.28e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CPLHMICO_00528	1.01e-63	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CPLHMICO_00529	3.8e-88	aroK	1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4	-	F	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	shikimate kinase activity
CPLHMICO_00530	7.43e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
CPLHMICO_00531	0.0	yhaN	-	-	L	-	-	-	AAA domain
CPLHMICO_00532	8.89e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
CPLHMICO_00533	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CPLHMICO_00534	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CPLHMICO_00535	7.86e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CPLHMICO_00536	9.99e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
CPLHMICO_00537	5.56e-125	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CPLHMICO_00539	3.69e-75	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CPLHMICO_00540	5.18e-76	-	-	-	-	-	-	-	-
CPLHMICO_00541	5.57e-134	-	-	-	S	-	-	-	SLAP domain
CPLHMICO_00542	1.13e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
CPLHMICO_00543	5.18e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
CPLHMICO_00544	3.01e-40	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
CPLHMICO_00545	2.13e-128	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
CPLHMICO_00546	1.35e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CPLHMICO_00548	5.56e-248	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
CPLHMICO_00549	8.03e-256	-	-	-	S	-	-	-	DUF218 domain
CPLHMICO_00550	7.53e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CPLHMICO_00551	1.09e-254	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
CPLHMICO_00552	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CPLHMICO_00553	1.04e-110	ykuL	-	-	S	-	-	-	(CBS) domain
CPLHMICO_00554	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
CPLHMICO_00555	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
CPLHMICO_00556	2.11e-221	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CPLHMICO_00557	7.07e-97	-	-	-	-	-	-	-	-
CPLHMICO_00558	1.31e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CPLHMICO_00559	6.66e-79	-	-	-	S	-	-	-	glycolate biosynthetic process
CPLHMICO_00560	6.88e-24	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
CPLHMICO_00561	3.57e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CPLHMICO_00562	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_00563	7e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CPLHMICO_00564	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CPLHMICO_00565	8.08e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CPLHMICO_00566	2.49e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CPLHMICO_00567	9.2e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CPLHMICO_00568	3.13e-38	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CPLHMICO_00569	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CPLHMICO_00570	7.57e-135	-	-	-	-	-	-	-	-
CPLHMICO_00571	6.11e-130	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
CPLHMICO_00572	5.49e-121	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
CPLHMICO_00573	1.4e-127	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CPLHMICO_00574	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CPLHMICO_00575	4.64e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
CPLHMICO_00576	1.3e-159	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
CPLHMICO_00577	1.35e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
CPLHMICO_00579	1.55e-271	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphodiester phosphodiesterase activity
CPLHMICO_00580	4.03e-75	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
CPLHMICO_00581	6.16e-21	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
CPLHMICO_00582	3.43e-34	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
CPLHMICO_00583	1.06e-17	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
CPLHMICO_00584	6.85e-164	-	-	-	S	-	-	-	VanZ like family
CPLHMICO_00585	2.08e-36	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CPLHMICO_00586	3.06e-46	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CPLHMICO_00587	2.5e-97	-	-	-	S	-	-	-	VanZ like family
CPLHMICO_00588	9.86e-23	-	-	-	M	-	-	-	NlpC/P60 family
CPLHMICO_00589	1.28e-133	-	-	-	M	-	-	-	NlpC/P60 family
CPLHMICO_00590	3.63e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
CPLHMICO_00591	1.53e-95	-	-	-	G	-	-	-	Peptidase_C39 like family
CPLHMICO_00592	2.82e-162	-	-	-	S	-	-	-	Acyltransferase family
CPLHMICO_00593	1.95e-19	-	-	-	S	-	-	-	Acyltransferase family
CPLHMICO_00594	2.8e-26	-	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00596	7.43e-86	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CPLHMICO_00597	5.78e-216	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CPLHMICO_00598	6.53e-91	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
CPLHMICO_00599	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CPLHMICO_00600	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CPLHMICO_00601	2.43e-118	-	-	-	GM	-	-	-	NmrA-like family
CPLHMICO_00602	2.31e-102	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CPLHMICO_00603	1.49e-98	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
CPLHMICO_00604	6.23e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CPLHMICO_00605	1.72e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CPLHMICO_00606	1.06e-256	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
CPLHMICO_00608	3.33e-32	pyrB	2.1.3.2	-	F	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CPLHMICO_00609	4.94e-59	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CPLHMICO_00610	3.44e-117	yfhC	-	-	C	-	-	-	Nitroreductase family
CPLHMICO_00611	2.84e-16	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CPLHMICO_00612	5.73e-149	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
CPLHMICO_00613	2.18e-74	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CPLHMICO_00614	2.5e-141	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CPLHMICO_00615	3.81e-111	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_00616	2.26e-154	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_00617	5.54e-213	-	-	-	EG	-	-	-	EamA-like transporter family
CPLHMICO_00618	1.45e-237	-	-	-	-	-	-	-	-
CPLHMICO_00619	8.41e-203	-	-	-	S	-	-	-	EDD domain protein, DegV family
CPLHMICO_00620	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CPLHMICO_00621	1.39e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CPLHMICO_00622	1.64e-57	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CPLHMICO_00623	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_00624	1.88e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CPLHMICO_00625	1.95e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CPLHMICO_00626	1.3e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPLHMICO_00627	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CPLHMICO_00628	3.03e-76	-	-	-	-	-	-	-	-
CPLHMICO_00629	2.42e-162	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CPLHMICO_00630	3.39e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CPLHMICO_00631	5.35e-85	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CPLHMICO_00632	8.99e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CPLHMICO_00633	6.44e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CPLHMICO_00634	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CPLHMICO_00635	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
CPLHMICO_00636	6.48e-243	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_00637	3.26e-78	-	-	-	I	-	-	-	acetylesterase activity
CPLHMICO_00638	4.46e-92	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
CPLHMICO_00639	5.85e-95	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_00640	3.66e-59	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_00641	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPLHMICO_00642	1.24e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
CPLHMICO_00643	2.72e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CPLHMICO_00644	4.53e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPLHMICO_00645	2.21e-72	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CPLHMICO_00646	1.46e-206	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CPLHMICO_00647	1.83e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CPLHMICO_00648	2.32e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPLHMICO_00649	2.21e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CPLHMICO_00650	3.6e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPLHMICO_00651	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CPLHMICO_00652	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPLHMICO_00653	1.93e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CPLHMICO_00654	1.79e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
CPLHMICO_00655	2.31e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CPLHMICO_00656	1.31e-199	-	-	-	-	-	-	-	-
CPLHMICO_00657	3.19e-59	-	-	-	-	-	-	-	-
CPLHMICO_00658	9.36e-20	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
CPLHMICO_00659	7.54e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
CPLHMICO_00660	1.33e-171	-	-	-	C	-	-	-	FAD binding domain
CPLHMICO_00661	6.36e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
CPLHMICO_00662	7.74e-56	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
CPLHMICO_00664	1.67e-86	-	-	-	L	-	-	-	Resolvase, N-terminal
CPLHMICO_00665	1.2e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
CPLHMICO_00666	4.63e-68	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
CPLHMICO_00667	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
CPLHMICO_00668	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00669	4.17e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CPLHMICO_00670	1.13e-223	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_00671	2.67e-101	-	-	-	V	ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
CPLHMICO_00672	1.07e-213	-	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
CPLHMICO_00673	6.38e-61	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
CPLHMICO_00674	1.63e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
CPLHMICO_00675	2.33e-156	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
CPLHMICO_00676	5.55e-79	-	-	-	-	-	-	-	-
CPLHMICO_00677	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
CPLHMICO_00681	1.55e-61	-	-	-	-	-	-	-	-
CPLHMICO_00682	1.96e-37	-	-	-	-	-	-	-	-
CPLHMICO_00684	1.21e-99	-	-	-	K	-	-	-	Transcriptional regulator
CPLHMICO_00685	5.15e-91	-	-	-	-	-	-	-	-
CPLHMICO_00686	3.27e-294	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CPLHMICO_00687	4.93e-243	-	-	-	S	-	-	-	Glycosyl transferase family 2
CPLHMICO_00688	4.45e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CPLHMICO_00689	3.27e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CPLHMICO_00690	5.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CPLHMICO_00691	3.07e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CPLHMICO_00692	7.32e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CPLHMICO_00693	4.23e-159	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPLHMICO_00694	1.92e-116	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPLHMICO_00695	3.04e-57	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CPLHMICO_00696	4.94e-65	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CPLHMICO_00697	3.19e-45	-	-	-	-	-	-	-	-
CPLHMICO_00698	5.81e-131	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
CPLHMICO_00699	1.34e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPLHMICO_00700	6.26e-101	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CPLHMICO_00701	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CPLHMICO_00702	7.38e-138	-	-	-	F	-	-	-	NUDIX domain
CPLHMICO_00703	3.88e-207	-	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00704	3.97e-232	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CPLHMICO_00705	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPLHMICO_00707	6.54e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CPLHMICO_00708	1.26e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
CPLHMICO_00709	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_00710	7.5e-122	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CPLHMICO_00711	2.91e-297	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CPLHMICO_00712	2.26e-112	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CPLHMICO_00713	4.78e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CPLHMICO_00714	1.41e-94	-	-	-	T	-	-	-	diguanylate cyclase
CPLHMICO_00715	6.04e-20	-	-	-	T	-	-	-	diguanylate cyclase
CPLHMICO_00716	3.58e-142	-	-	-	T	-	-	-	EAL domain
CPLHMICO_00717	9.89e-15	-	-	-	T	-	-	-	diguanylate cyclase
CPLHMICO_00718	1.03e-111	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CPLHMICO_00719	0.0	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CPLHMICO_00720	3.51e-186	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
CPLHMICO_00721	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00722	3.8e-130	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
CPLHMICO_00723	2.84e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
CPLHMICO_00724	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CPLHMICO_00725	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
CPLHMICO_00726	1.27e-217	potA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CPLHMICO_00727	1.78e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CPLHMICO_00729	5.19e-188	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
CPLHMICO_00730	5.19e-226	-	-	-	S	-	-	-	Glycosyltransferase like family 2
CPLHMICO_00731	4.9e-239	-	-	-	M	-	-	-	Glycosyl transferase family 2
CPLHMICO_00732	7.84e-284	cps3F	-	-	-	-	-	-	-
CPLHMICO_00733	2.19e-223	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CPLHMICO_00734	1.16e-243	cps2G	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
CPLHMICO_00735	4.4e-247	-	-	-	S	-	-	-	Acyltransferase family
CPLHMICO_00736	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CPLHMICO_00737	3.76e-78	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CPLHMICO_00738	5.03e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
CPLHMICO_00739	8.27e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
CPLHMICO_00740	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CPLHMICO_00741	1.95e-119	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CPLHMICO_00742	5.99e-137	-	-	-	S	-	-	-	SNARE associated Golgi protein
CPLHMICO_00743	9.49e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CPLHMICO_00744	2.83e-202	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CPLHMICO_00745	1.32e-122	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
CPLHMICO_00746	3.44e-167	-	-	-	F	-	-	-	glutamine amidotransferase
CPLHMICO_00747	2.83e-70	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
CPLHMICO_00748	5.62e-66	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
CPLHMICO_00750	1.01e-104	cydD1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
CPLHMICO_00751	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CPLHMICO_00752	1.26e-95	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CPLHMICO_00753	7.59e-287	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CPLHMICO_00754	2.93e-280	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
CPLHMICO_00755	5.43e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CPLHMICO_00756	3.71e-106	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CPLHMICO_00757	1.19e-21	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CPLHMICO_00758	4.92e-74	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CPLHMICO_00759	8.26e-106	-	-	-	-	-	-	-	-
CPLHMICO_00760	6.88e-26	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
CPLHMICO_00762	1.96e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00763	3.52e-275	-	-	-	S	-	-	-	FtsX-like permease family
CPLHMICO_00766	1.4e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CPLHMICO_00767	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CPLHMICO_00768	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CPLHMICO_00769	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CPLHMICO_00770	2.67e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPLHMICO_00771	1.06e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CPLHMICO_00772	1.98e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
CPLHMICO_00780	3.91e-245	potA11	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CPLHMICO_00781	1.73e-175	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_00782	1.93e-179	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_00783	2.09e-67	-	-	-	L	-	-	-	Transposase DDE domain
CPLHMICO_00784	3.26e-156	-	-	-	L	-	-	-	Transposase DDE domain
CPLHMICO_00785	7.09e-162	-	-	-	L	-	-	-	Transposase DDE domain
CPLHMICO_00788	2.18e-25	-	-	-	L	-	-	-	PFAM Integrase core domain
CPLHMICO_00789	1.06e-187	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00790	7.75e-201	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_00791	4.83e-48	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CPLHMICO_00792	1.49e-133	-	-	-	-	-	-	-	-
CPLHMICO_00793	5.63e-77	-	-	-	K	-	-	-	sequence-specific DNA binding
CPLHMICO_00794	2.5e-233	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
CPLHMICO_00795	5.16e-55	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPLHMICO_00796	4.1e-60	luxA_2	-	-	C	-	-	-	Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
CPLHMICO_00797	4.67e-127	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
CPLHMICO_00798	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
CPLHMICO_00799	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
CPLHMICO_00800	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00801	7.24e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_00804	7.93e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CPLHMICO_00806	1.48e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CPLHMICO_00807	9.6e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CPLHMICO_00808	1.1e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_00809	3.99e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CPLHMICO_00810	3.68e-202	yicL	-	-	EG	-	-	-	EamA-like transporter family
CPLHMICO_00811	4.51e-65	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CPLHMICO_00812	7.26e-39	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
CPLHMICO_00813	1.43e-92	-	-	-	E	-	-	-	Methionine synthase
CPLHMICO_00814	2.08e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
CPLHMICO_00815	1.79e-214	-	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00816	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CPLHMICO_00817	6.58e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CPLHMICO_00818	4.71e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPLHMICO_00819	4.29e-41	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
CPLHMICO_00820	3.95e-224	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_00821	2.12e-70	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
CPLHMICO_00822	1.45e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CPLHMICO_00823	5.16e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CPLHMICO_00824	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CPLHMICO_00825	1.71e-76	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
CPLHMICO_00826	1.07e-39	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
CPLHMICO_00827	4.25e-66	-	-	-	L	-	-	-	Transposase and inactivated derivatives
CPLHMICO_00828	3.04e-257	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CPLHMICO_00829	2.83e-25	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
CPLHMICO_00830	4.2e-250	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CPLHMICO_00831	2.36e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPLHMICO_00832	9.86e-282	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CPLHMICO_00833	6.61e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CPLHMICO_00834	7.35e-221	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPLHMICO_00835	3.15e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CPLHMICO_00836	1.29e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CPLHMICO_00837	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CPLHMICO_00838	4.51e-236	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPLHMICO_00839	1.38e-37	-	-	-	-	-	-	-	-
CPLHMICO_00841	3.85e-201	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CPLHMICO_00842	1.1e-47	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00843	7.02e-63	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00844	5.88e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CPLHMICO_00845	8.79e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
CPLHMICO_00846	8.86e-09	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CPLHMICO_00847	6.57e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CPLHMICO_00848	5.35e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CPLHMICO_00849	4.9e-72	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CPLHMICO_00850	1.27e-147	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
CPLHMICO_00851	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
CPLHMICO_00852	8.77e-63	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
CPLHMICO_00853	1.52e-62	-	-	-	-	-	-	-	-
CPLHMICO_00854	1.35e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
CPLHMICO_00856	1.6e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
CPLHMICO_00857	1.95e-257	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CPLHMICO_00858	2.06e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CPLHMICO_00859	2.88e-272	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CPLHMICO_00860	4.4e-29	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
CPLHMICO_00861	5.4e-125	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
CPLHMICO_00862	1.23e-57	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
CPLHMICO_00863	2.37e-50	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CPLHMICO_00864	1.83e-258	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPLHMICO_00865	5.45e-77	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CPLHMICO_00866	2.04e-38	-	-	-	-	-	-	-	-
CPLHMICO_00867	1.62e-265	-	-	-	G	-	-	-	Major Facilitator Superfamily
CPLHMICO_00868	2.16e-07	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
CPLHMICO_00870	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CPLHMICO_00871	1.99e-203	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPLHMICO_00872	2.91e-294	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CPLHMICO_00873	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CPLHMICO_00874	6.15e-235	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
CPLHMICO_00875	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CPLHMICO_00876	3.7e-294	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPLHMICO_00877	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CPLHMICO_00878	4.62e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CPLHMICO_00879	8.57e-177	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CPLHMICO_00880	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CPLHMICO_00881	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CPLHMICO_00882	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
CPLHMICO_00883	5.63e-45	-	-	-	-	-	-	-	-
CPLHMICO_00885	1.37e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
CPLHMICO_00886	1.39e-18	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
CPLHMICO_00887	1.38e-115	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CPLHMICO_00888	2.87e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CPLHMICO_00889	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CPLHMICO_00890	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CPLHMICO_00891	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CPLHMICO_00892	1.47e-28	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	anion transmembrane transporter activity
CPLHMICO_00894	4.63e-120	-	-	-	I	-	-	-	Acyltransferase family
CPLHMICO_00895	5.11e-208	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CPLHMICO_00896	8.85e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CPLHMICO_00897	2.22e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CPLHMICO_00898	2.77e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CPLHMICO_00899	2.16e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPLHMICO_00900	4.13e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CPLHMICO_00901	5.52e-149	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CPLHMICO_00902	5.23e-06	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CPLHMICO_00903	1.22e-139	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CPLHMICO_00904	1.24e-279	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CPLHMICO_00905	2.29e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CPLHMICO_00906	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CPLHMICO_00907	2.38e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CPLHMICO_00908	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CPLHMICO_00909	4.97e-220	-	-	-	K	-	-	-	LysR substrate binding domain
CPLHMICO_00910	1.77e-11	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CPLHMICO_00911	6.12e-149	-	-	-	K	ko:K13928	-	ko00000,ko03000	DNA-binding transcription factor activity
CPLHMICO_00912	9.11e-36	-	-	-	-	-	-	-	-
CPLHMICO_00913	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPLHMICO_00914	5.36e-93	-	-	-	-	-	-	-	-
CPLHMICO_00915	8.45e-254	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CPLHMICO_00919	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
CPLHMICO_00920	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
CPLHMICO_00921	1.41e-142	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
CPLHMICO_00922	6.88e-237	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
CPLHMICO_00923	3.84e-169	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
CPLHMICO_00924	1.47e-151	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
CPLHMICO_00925	2.28e-223	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CPLHMICO_00926	6.39e-201	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
CPLHMICO_00929	8.24e-20	-	-	-	-	-	-	-	-
CPLHMICO_00930	4.63e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
CPLHMICO_00931	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CPLHMICO_00932	9.39e-184	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CPLHMICO_00933	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CPLHMICO_00934	2.34e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
CPLHMICO_00935	2.02e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CPLHMICO_00937	5.48e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
CPLHMICO_00938	1.45e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
CPLHMICO_00939	1.62e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_00940	1.14e-193	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_00941	4.64e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_00942	4.57e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_00943	2.93e-197	-	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CPLHMICO_00944	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CPLHMICO_00945	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CPLHMICO_00946	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CPLHMICO_00948	5.09e-51	-	-	-	-	-	-	-	-
CPLHMICO_00949	1.6e-114	-	-	-	-	-	-	-	-
CPLHMICO_00950	7.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPLHMICO_00951	1.06e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CPLHMICO_00952	6.1e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CPLHMICO_00953	2.57e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CPLHMICO_00954	3.82e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CPLHMICO_00955	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CPLHMICO_00958	1.2e-22	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CPLHMICO_00959	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
CPLHMICO_00960	5.18e-134	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CPLHMICO_00961	4.62e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
CPLHMICO_00962	1.23e-158	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CPLHMICO_00963	4.35e-282	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CPLHMICO_00964	2.6e-314	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CPLHMICO_00966	1.75e-234	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CPLHMICO_00967	5.67e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CPLHMICO_00968	2.15e-299	ynbB	-	-	P	-	-	-	aluminum resistance
CPLHMICO_00969	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
CPLHMICO_00971	2.17e-51	-	-	-	E	-	-	-	Amino acid permease
CPLHMICO_00972	2.54e-176	-	-	-	E	-	-	-	Amino acid permease
CPLHMICO_00973	7.82e-34	-	-	-	-	-	-	-	-
CPLHMICO_00974	2.03e-272	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CPLHMICO_00975	1.74e-106	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
CPLHMICO_00976	8.2e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CPLHMICO_00977	3.34e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CPLHMICO_00978	1.47e-213	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CPLHMICO_00979	3.93e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CPLHMICO_00981	5.03e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CPLHMICO_00982	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPLHMICO_00983	1.89e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CPLHMICO_00984	1.75e-110	-	-	-	-	-	-	-	-
CPLHMICO_00985	7.41e-97	-	-	-	-	-	-	-	-
CPLHMICO_00986	1.07e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
CPLHMICO_00987	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CPLHMICO_00988	9.06e-27	-	-	-	-	-	-	-	-
CPLHMICO_00989	6.63e-265	sufI	-	-	Q	-	-	-	Multicopper oxidase
CPLHMICO_00990	5.23e-88	sufI	-	-	Q	-	-	-	Multicopper oxidase
CPLHMICO_00991	4.54e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
CPLHMICO_00992	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CPLHMICO_00994	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CPLHMICO_00995	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPLHMICO_00996	3.22e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CPLHMICO_00997	1.5e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CPLHMICO_00998	1.17e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CPLHMICO_00999	6.36e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
CPLHMICO_01000	4.73e-140	-	-	-	S	-	-	-	CYTH
CPLHMICO_01001	1.34e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CPLHMICO_01002	7.48e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CPLHMICO_01003	8.2e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CPLHMICO_01004	7.7e-31	-	-	-	-	-	-	-	-
CPLHMICO_01005	3.14e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CPLHMICO_01006	4.79e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CPLHMICO_01007	7.79e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
CPLHMICO_01008	5.85e-255	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
CPLHMICO_01009	3.13e-133	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CPLHMICO_01010	1.81e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
CPLHMICO_01011	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CPLHMICO_01012	1.89e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CPLHMICO_01013	1.99e-300	ymfH	-	-	S	-	-	-	Peptidase M16
CPLHMICO_01014	1.33e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CPLHMICO_01015	8.57e-161	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
CPLHMICO_01016	1.87e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CPLHMICO_01017	1.13e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPLHMICO_01018	1.65e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CPLHMICO_01019	1.88e-273	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
CPLHMICO_01020	2.7e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CPLHMICO_01021	2.9e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CPLHMICO_01022	3.15e-155	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CPLHMICO_01023	2.28e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPLHMICO_01024	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CPLHMICO_01025	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CPLHMICO_01026	2.72e-57	-	-	-	-	-	-	-	-
CPLHMICO_01027	2.67e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CPLHMICO_01028	9.5e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CPLHMICO_01029	1.36e-242	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CPLHMICO_01030	2.48e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CPLHMICO_01031	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CPLHMICO_01032	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CPLHMICO_01033	9.33e-119	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CPLHMICO_01034	2.61e-188	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
CPLHMICO_01035	2.58e-108	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
CPLHMICO_01036	1.16e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CPLHMICO_01037	2.75e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CPLHMICO_01038	1.26e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CPLHMICO_01039	1.21e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CPLHMICO_01040	1.87e-32	-	-	-	-	-	-	-	-
CPLHMICO_01041	2.73e-269	-	-	-	-	-	-	-	-
CPLHMICO_01042	1.98e-40	ABC-SBP	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
CPLHMICO_01043	5.15e-66	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CPLHMICO_01044	2.84e-146	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_01046	4.59e-270	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
CPLHMICO_01047	1.42e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CPLHMICO_01048	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CPLHMICO_01049	1.83e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CPLHMICO_01050	2.01e-34	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
CPLHMICO_01051	5.86e-31	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
CPLHMICO_01052	3.12e-135	-	-	-	-	-	-	-	-
CPLHMICO_01053	9.09e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_01054	1.77e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPLHMICO_01055	9.44e-234	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CPLHMICO_01056	1.13e-112	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CPLHMICO_01057	9.43e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CPLHMICO_01058	1.77e-206	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CPLHMICO_01059	6.4e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CPLHMICO_01060	9.32e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_01061	2.96e-174	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_01062	4.19e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01063	1.1e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CPLHMICO_01064	2.74e-215	ybbR	-	-	S	-	-	-	YbbR-like protein
CPLHMICO_01065	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPLHMICO_01066	1.1e-191	-	-	-	S	-	-	-	hydrolase
CPLHMICO_01067	6.52e-75	-	-	-	V	-	-	-	peptidase activity
CPLHMICO_01068	3.22e-103	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CPLHMICO_01069	6e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
CPLHMICO_01070	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CPLHMICO_01071	2.7e-86	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPLHMICO_01072	2.04e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPLHMICO_01073	2.89e-178	-	-	-	-	-	-	-	-
CPLHMICO_01074	4.87e-190	-	-	-	T	-	-	-	diguanylate cyclase activity
CPLHMICO_01075	1.29e-232	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CPLHMICO_01076	4.03e-150	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CPLHMICO_01077	4.84e-161	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CPLHMICO_01079	3.45e-86	-	-	-	-	-	-	-	-
CPLHMICO_01080	3.19e-110	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPLHMICO_01081	2.61e-83	-	-	-	GM	-	-	-	epimerase
CPLHMICO_01082	0.0	-	-	-	E	-	-	-	Amino acid permease
CPLHMICO_01083	4.18e-133	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPLHMICO_01084	3.26e-203	-	-	-	S	-	-	-	Phospholipase, patatin family
CPLHMICO_01085	3.33e-209	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CPLHMICO_01086	9.45e-121	-	-	-	S	-	-	-	VanZ like family
CPLHMICO_01087	1.01e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CPLHMICO_01088	2.81e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CPLHMICO_01089	1.43e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CPLHMICO_01090	2.72e-67	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
CPLHMICO_01091	3e-98	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
CPLHMICO_01094	1.77e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CPLHMICO_01095	4.9e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CPLHMICO_01098	7.74e-173	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
CPLHMICO_01099	0.0	yclK	-	-	T	-	-	-	Histidine kinase
CPLHMICO_01100	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CPLHMICO_01101	5.95e-147	vanZ	-	-	V	-	-	-	VanZ like family
CPLHMICO_01102	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CPLHMICO_01103	3.94e-110	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01104	2.23e-227	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01107	1.21e-243	ampC	-	-	V	-	-	-	Beta-lactamase
CPLHMICO_01108	3.69e-45	-	-	-	-	-	-	-	-
CPLHMICO_01109	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
CPLHMICO_01110	1.08e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CPLHMICO_01111	2.77e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPLHMICO_01112	3.44e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CPLHMICO_01113	3.07e-240	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CPLHMICO_01114	3.18e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CPLHMICO_01115	9.32e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CPLHMICO_01116	7.13e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPLHMICO_01117	6.38e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPLHMICO_01118	2.9e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPLHMICO_01119	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CPLHMICO_01120	1.66e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CPLHMICO_01121	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CPLHMICO_01122	7.32e-95	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CPLHMICO_01123	7.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
CPLHMICO_01124	5.61e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CPLHMICO_01125	4.4e-64	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
CPLHMICO_01126	6.23e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CPLHMICO_01127	1.19e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CPLHMICO_01128	2.07e-102	uspA	-	-	T	-	-	-	universal stress protein
CPLHMICO_01129	5.05e-57	-	-	-	-	-	-	-	-
CPLHMICO_01130	5.39e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CPLHMICO_01131	2.41e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CPLHMICO_01132	3.59e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CPLHMICO_01133	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CPLHMICO_01134	8.03e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CPLHMICO_01135	9.32e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPLHMICO_01136	2.38e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CPLHMICO_01137	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CPLHMICO_01138	1.57e-299	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CPLHMICO_01139	2.82e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CPLHMICO_01140	3.2e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CPLHMICO_01141	9.63e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CPLHMICO_01142	2.17e-175	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CPLHMICO_01143	2.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
CPLHMICO_01145	2.49e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
CPLHMICO_01146	1.01e-64	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CPLHMICO_01147	7.63e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CPLHMICO_01148	1.14e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
CPLHMICO_01149	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CPLHMICO_01150	1.09e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPLHMICO_01151	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPLHMICO_01152	2.35e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPLHMICO_01153	3.01e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CPLHMICO_01154	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CPLHMICO_01155	4.44e-308	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPLHMICO_01156	3.21e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CPLHMICO_01157	7.21e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CPLHMICO_01158	6.89e-188	ylmH	-	-	S	-	-	-	S4 domain protein
CPLHMICO_01159	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CPLHMICO_01160	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CPLHMICO_01161	3.66e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CPLHMICO_01162	3.72e-36	-	-	-	-	-	-	-	-
CPLHMICO_01163	1.56e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPLHMICO_01164	3.66e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CPLHMICO_01165	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CPLHMICO_01166	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CPLHMICO_01167	7.5e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
CPLHMICO_01168	8.69e-149	-	-	-	S	-	-	-	repeat protein
CPLHMICO_01169	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CPLHMICO_01170	7.85e-45	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
CPLHMICO_01171	4.65e-299	-	-	-	L	-	-	-	Transposase
CPLHMICO_01188	1.1e-176	-	-	-	G	-	-	-	Major Facilitator Superfamily
CPLHMICO_01190	3.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
CPLHMICO_01191	5.84e-123	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
CPLHMICO_01193	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CPLHMICO_01194	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CPLHMICO_01195	2.21e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CPLHMICO_01196	1.05e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CPLHMICO_01197	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CPLHMICO_01198	4.68e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CPLHMICO_01199	2.52e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPLHMICO_01200	8.25e-219	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CPLHMICO_01201	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CPLHMICO_01202	1.14e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CPLHMICO_01204	3.6e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CPLHMICO_01205	4.33e-71	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
CPLHMICO_01206	3.17e-51	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CPLHMICO_01208	3.62e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CPLHMICO_01209	3.27e-59	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
CPLHMICO_01210	6.01e-45	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
CPLHMICO_01211	1.89e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
CPLHMICO_01212	9.36e-111	-	-	-	S	-	-	-	YcxB-like protein
CPLHMICO_01213	1.18e-137	-	-	-	T	-	-	-	integral membrane protein
CPLHMICO_01214	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CPLHMICO_01215	6.48e-117	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CPLHMICO_01216	3.56e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CPLHMICO_01217	8.13e-38	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CPLHMICO_01218	1.14e-245	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CPLHMICO_01219	7.25e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_01220	8.38e-188	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
CPLHMICO_01221	3e-61	-	-	-	C	-	-	-	FAD linked oxidase domain protein
CPLHMICO_01222	1.23e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CPLHMICO_01223	1.56e-198	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CPLHMICO_01224	2.13e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CPLHMICO_01225	1.93e-228	-	-	-	-	-	-	-	-
CPLHMICO_01226	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CPLHMICO_01227	2.71e-126	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CPLHMICO_01228	2.2e-36	-	-	-	-	-	-	-	-
CPLHMICO_01229	1.19e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CPLHMICO_01230	1.7e-208	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CPLHMICO_01231	8.98e-224	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CPLHMICO_01232	1.36e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CPLHMICO_01233	2.09e-136	-	-	-	-	-	-	-	-
CPLHMICO_01234	6.86e-56	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
CPLHMICO_01235	1.05e-174	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
CPLHMICO_01236	1.52e-201	dkgB	-	-	S	-	-	-	reductase
CPLHMICO_01238	4.46e-45	-	-	-	GK	-	-	-	ROK family
CPLHMICO_01239	1.55e-50	-	-	-	GK	-	-	-	ROK family
CPLHMICO_01240	2.39e-12	-	-	-	S	-	-	-	PAS domain
CPLHMICO_01241	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
CPLHMICO_01242	1.6e-269	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CPLHMICO_01243	9.8e-134	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
CPLHMICO_01244	1.35e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CPLHMICO_01245	1.42e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CPLHMICO_01246	2.35e-112	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01247	9e-185	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01248	6.64e-31	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
CPLHMICO_01249	4.86e-76	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CPLHMICO_01251	1.22e-15	rpiB2	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
CPLHMICO_01252	1.84e-27	-	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
CPLHMICO_01253	1.49e-54	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CPLHMICO_01254	2.38e-273	pbpX	-	-	V	-	-	-	Beta-lactamase
CPLHMICO_01255	1.83e-166	-	-	-	M	-	-	-	Glycosyltransferase Family 4
CPLHMICO_01256	7e-201	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
CPLHMICO_01257	3.18e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
CPLHMICO_01258	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CPLHMICO_01259	3.28e-145	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CPLHMICO_01260	2.53e-162	epsB	-	-	M	-	-	-	biosynthesis protein
CPLHMICO_01261	3.98e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_01262	5.24e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPLHMICO_01263	3.55e-162	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01264	3.28e-120	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01265	1.3e-42	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01266	3.16e-29	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01267	5.78e-09	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01268	2.36e-156	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CPLHMICO_01269	1.01e-104	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
CPLHMICO_01270	3.81e-254	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPLHMICO_01271	1.74e-107	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
CPLHMICO_01272	9.03e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
CPLHMICO_01273	2.89e-64	-	-	-	-	-	-	-	-
CPLHMICO_01274	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
CPLHMICO_01275	3.17e-142	-	-	-	-	-	-	-	-
CPLHMICO_01276	1.96e-102	-	-	-	-	-	-	-	-
CPLHMICO_01277	1.27e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CPLHMICO_01278	1.37e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
CPLHMICO_01279	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CPLHMICO_01281	1.12e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CPLHMICO_01282	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CPLHMICO_01283	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CPLHMICO_01284	1.01e-84	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01285	5.12e-42	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01286	6.16e-54	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01287	2.23e-105	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01288	9.16e-69	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01289	1.15e-86	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CPLHMICO_01290	5.2e-222	-	-	-	-	-	-	-	-
CPLHMICO_01291	6.72e-207	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01292	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
CPLHMICO_01293	1.82e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
CPLHMICO_01294	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
CPLHMICO_01295	8.77e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CPLHMICO_01296	2.1e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CPLHMICO_01297	1.51e-26	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_01299	1.78e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
CPLHMICO_01300	4.11e-160	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CPLHMICO_01302	3.02e-19	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CPLHMICO_01304	1.93e-209	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
CPLHMICO_01305	1.09e-51	-	-	-	-	-	-	-	-
CPLHMICO_01306	6.66e-159	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
CPLHMICO_01307	8.05e-166	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
CPLHMICO_01308	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01309	8.7e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_01310	1.55e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CPLHMICO_01311	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CPLHMICO_01312	1.97e-107	XK27_08850	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
CPLHMICO_01314	2.82e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPLHMICO_01315	0.0	bmr3_1	-	-	EGP	ko:K18935	-	ko00000,ko02000	Sugar (and other) transporter
CPLHMICO_01316	2.31e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
CPLHMICO_01317	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CPLHMICO_01318	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
CPLHMICO_01319	3.32e-62	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
CPLHMICO_01320	6.41e-148	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CPLHMICO_01321	4.2e-208	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CPLHMICO_01322	6.29e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CPLHMICO_01324	5.01e-209	-	-	-	S	-	-	-	amidohydrolase
CPLHMICO_01325	4.05e-09	XK27_07210	-	-	S	-	-	-	B3 4 domain
CPLHMICO_01326	2.12e-135	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CPLHMICO_01327	1.16e-132	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
CPLHMICO_01329	2.41e-253	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
CPLHMICO_01330	1.54e-34	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_01331	6.47e-110	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_01333	5.78e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
CPLHMICO_01334	4.26e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CPLHMICO_01335	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CPLHMICO_01336	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPLHMICO_01337	2.84e-101	-	-	-	S	-	-	-	Helix-turn-helix domain
CPLHMICO_01338	1.24e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CPLHMICO_01339	3.13e-252	-	-	-	-	-	-	-	-
CPLHMICO_01340	3.77e-291	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
CPLHMICO_01341	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPLHMICO_01342	3.04e-48	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CPLHMICO_01343	6.85e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CPLHMICO_01344	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CPLHMICO_01345	1.95e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CPLHMICO_01346	1.31e-70	ylbG	-	-	S	-	-	-	UPF0298 protein
CPLHMICO_01347	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CPLHMICO_01348	2.65e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPLHMICO_01349	1.53e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CPLHMICO_01350	1.36e-112	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CPLHMICO_01351	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CPLHMICO_01352	1.83e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CPLHMICO_01353	7.29e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CPLHMICO_01354	1.02e-52	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CPLHMICO_01355	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPLHMICO_01356	2.69e-190	-	-	-	-	-	-	-	-
CPLHMICO_01357	7.85e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPLHMICO_01358	9.52e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CPLHMICO_01359	1.83e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPLHMICO_01360	3.33e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CPLHMICO_01361	3.4e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
CPLHMICO_01362	6.71e-200	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
CPLHMICO_01363	2.77e-08	-	-	-	-	-	-	-	-
CPLHMICO_01364	3.44e-161	pnb	-	-	C	-	-	-	nitroreductase
CPLHMICO_01366	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01367	3.58e-85	-	-	-	-	-	-	-	-
CPLHMICO_01368	6.9e-157	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CPLHMICO_01369	2.34e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CPLHMICO_01370	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CPLHMICO_01371	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CPLHMICO_01372	4.71e-169	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CPLHMICO_01373	1.63e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPLHMICO_01374	1.2e-149	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_01375	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CPLHMICO_01376	6.69e-171	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
CPLHMICO_01377	3.24e-219	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
CPLHMICO_01382	5.08e-72	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	MafB19-like deaminase
CPLHMICO_01383	6.76e-16	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CPLHMICO_01384	9.99e-254	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CPLHMICO_01385	9.07e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CPLHMICO_01386	6.94e-199	-	-	-	K	-	-	-	LysR family
CPLHMICO_01387	9.72e-47	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CPLHMICO_01388	3e-83	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CPLHMICO_01389	1.11e-160	-	-	-	T	-	-	-	diguanylate cyclase
CPLHMICO_01390	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
CPLHMICO_01391	7.46e-50	-	-	-	-	-	-	-	-
CPLHMICO_01392	3.87e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
CPLHMICO_01393	1.87e-33	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPLHMICO_01394	7.42e-47	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPLHMICO_01395	2.2e-184	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPLHMICO_01396	7.56e-108	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CPLHMICO_01397	2e-311	-	-	-	KLT	-	-	-	serine threonine protein kinase
CPLHMICO_01398	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_01399	4.56e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CPLHMICO_01400	2.18e-117	ymdB	-	-	S	-	-	-	Macro domain protein
CPLHMICO_01401	2.88e-47	-	-	-	-	-	-	-	-
CPLHMICO_01402	1.73e-196	-	-	-	-	-	-	-	-
CPLHMICO_01404	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CPLHMICO_01405	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CPLHMICO_01407	1.12e-301	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CPLHMICO_01408	4.89e-12	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CPLHMICO_01409	8.61e-223	citI	-	-	K	-	-	-	Putative sugar-binding domain
CPLHMICO_01410	2.67e-51	lysM	-	-	M	-	-	-	LysM domain
CPLHMICO_01411	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CPLHMICO_01412	4.25e-47	drgA	-	-	C	-	-	-	coenzyme F420-1:gamma-L-glutamate ligase activity
CPLHMICO_01413	7.02e-288	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CPLHMICO_01414	6.95e-152	-	-	-	-	-	-	-	-
CPLHMICO_01415	7.19e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CPLHMICO_01416	5.02e-22	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
CPLHMICO_01417	7.03e-92	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
CPLHMICO_01419	2.38e-140	-	-	-	-	-	-	-	-
CPLHMICO_01420	1.14e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CPLHMICO_01422	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CPLHMICO_01423	4.76e-127	-	-	-	K	-	-	-	WHG domain
CPLHMICO_01424	2.92e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
CPLHMICO_01425	6.08e-125	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
CPLHMICO_01426	3.54e-183	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CPLHMICO_01427	1.35e-237	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CPLHMICO_01428	7.44e-113	cvpA	-	-	S	-	-	-	Colicin V production protein
CPLHMICO_01429	1.5e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CPLHMICO_01430	1.09e-184	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CPLHMICO_01431	2.37e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CPLHMICO_01432	4.14e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CPLHMICO_01433	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CPLHMICO_01434	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CPLHMICO_01435	2.68e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CPLHMICO_01436	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_01437	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CPLHMICO_01438	3.03e-159	vanR	-	-	K	-	-	-	response regulator
CPLHMICO_01439	2.83e-281	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
CPLHMICO_01440	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPLHMICO_01441	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CPLHMICO_01442	3.02e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
CPLHMICO_01443	5.74e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CPLHMICO_01444	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
CPLHMICO_01445	1.75e-186	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
CPLHMICO_01446	6.92e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CPLHMICO_01447	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CPLHMICO_01448	5.07e-74	-	-	-	KT	-	-	-	response to antibiotic
CPLHMICO_01449	2.12e-126	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
CPLHMICO_01450	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
CPLHMICO_01451	1.2e-30	-	-	-	L	-	-	-	Transposase
CPLHMICO_01452	1.67e-28	-	-	-	L	-	-	-	DDE superfamily endonuclease
CPLHMICO_01455	5.43e-97	-	-	-	-	-	-	-	-
CPLHMICO_01456	0.0	-	-	-	E	-	-	-	Amino acid permease
CPLHMICO_01457	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
CPLHMICO_01458	4.71e-98	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CPLHMICO_01459	1.96e-158	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CPLHMICO_01460	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CPLHMICO_01461	9.39e-256	-	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CPLHMICO_01462	1.86e-103	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CPLHMICO_01463	2.72e-72	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CPLHMICO_01464	6.28e-136	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CPLHMICO_01465	1.52e-175	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
CPLHMICO_01466	3.18e-34	-	-	-	-	-	-	-	-
CPLHMICO_01467	3.2e-137	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CPLHMICO_01468	5.93e-129	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CPLHMICO_01469	2.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_01470	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CPLHMICO_01472	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CPLHMICO_01473	0.0	-	-	-	S	-	-	-	SH3-like domain
CPLHMICO_01474	4.48e-296	-	-	-	-	-	-	-	-
CPLHMICO_01475	1.95e-127	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
CPLHMICO_01476	1.75e-65	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CPLHMICO_01477	1.63e-67	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CPLHMICO_01478	1.66e-55	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
CPLHMICO_01479	6.03e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPLHMICO_01480	1.94e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CPLHMICO_01481	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPLHMICO_01482	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CPLHMICO_01483	8.7e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPLHMICO_01484	1.98e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPLHMICO_01485	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPLHMICO_01486	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPLHMICO_01487	2.39e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CPLHMICO_01488	1.17e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPLHMICO_01489	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CPLHMICO_01490	1.87e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CPLHMICO_01491	3.41e-73	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01492	1.29e-118	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CPLHMICO_01493	6.33e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
CPLHMICO_01494	5.61e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CPLHMICO_01495	3.79e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CPLHMICO_01496	3.27e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CPLHMICO_01497	3.92e-131	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPLHMICO_01498	6.3e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CPLHMICO_01499	7.64e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPLHMICO_01500	9.2e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CPLHMICO_01501	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CPLHMICO_01502	2.38e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CPLHMICO_01503	1.16e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CPLHMICO_01504	5.49e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CPLHMICO_01505	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CPLHMICO_01506	3.4e-61	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
CPLHMICO_01507	1.2e-17	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01508	1.13e-44	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
CPLHMICO_01509	8.37e-66	-	-	-	-	-	-	-	-
CPLHMICO_01510	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CPLHMICO_01511	1.28e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CPLHMICO_01512	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPLHMICO_01513	3e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPLHMICO_01514	7.7e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPLHMICO_01515	2.69e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CPLHMICO_01516	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CPLHMICO_01517	8.19e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CPLHMICO_01518	5.26e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CPLHMICO_01523	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
CPLHMICO_01524	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CPLHMICO_01525	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CPLHMICO_01526	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CPLHMICO_01527	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPLHMICO_01528	3.56e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CPLHMICO_01529	1.31e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPLHMICO_01530	3.75e-242	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CPLHMICO_01531	2.9e-227	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CPLHMICO_01532	2.21e-227	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CPLHMICO_01533	4.18e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CPLHMICO_01534	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_01535	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_01536	2.5e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CPLHMICO_01537	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CPLHMICO_01538	6.49e-210	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CPLHMICO_01539	4.4e-34	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CPLHMICO_01540	2.27e-71	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CPLHMICO_01541	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPLHMICO_01542	3.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CPLHMICO_01543	4.06e-118	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPLHMICO_01544	2.81e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CPLHMICO_01547	1.04e-169	snf	-	-	KL	-	-	-	domain protein
CPLHMICO_01548	1.63e-259	snf	-	-	KL	-	-	-	domain protein
CPLHMICO_01549	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CPLHMICO_01550	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CPLHMICO_01551	0.0	-	-	-	S	-	-	-	TerB-C domain
CPLHMICO_01552	1.89e-316	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
CPLHMICO_01553	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
CPLHMICO_01554	3.28e-122	-	-	-	-	-	-	-	-
CPLHMICO_01555	1.44e-198	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CPLHMICO_01556	1.68e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
CPLHMICO_01557	2.53e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CPLHMICO_01558	1.5e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
CPLHMICO_01559	1.55e-42	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
CPLHMICO_01560	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01561	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CPLHMICO_01562	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
CPLHMICO_01563	2.28e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
CPLHMICO_01564	1.3e-315	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CPLHMICO_01565	8.02e-230	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPLHMICO_01566	1.31e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CPLHMICO_01567	8.18e-243	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CPLHMICO_01568	1.49e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CPLHMICO_01569	3.29e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CPLHMICO_01570	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CPLHMICO_01571	2.75e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CPLHMICO_01572	3.99e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPLHMICO_01573	1.97e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CPLHMICO_01574	5.84e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CPLHMICO_01575	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CPLHMICO_01576	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPLHMICO_01577	1.01e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CPLHMICO_01578	5.54e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CPLHMICO_01579	1.03e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CPLHMICO_01580	2.5e-57	ylxQ	-	-	J	-	-	-	ribosomal protein
CPLHMICO_01581	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CPLHMICO_01582	2.57e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CPLHMICO_01583	1.31e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPLHMICO_01586	4.64e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
CPLHMICO_01587	1.44e-142	-	-	-	-	-	-	-	-
CPLHMICO_01588	1.9e-56	-	-	-	L	-	-	-	Membrane
CPLHMICO_01589	2.32e-187	-	-	-	F	-	-	-	NUDIX domain
CPLHMICO_01590	1.14e-38	-	-	-	S	-	-	-	Enterocin A Immunity
CPLHMICO_01592	2.95e-146	-	-	-	E	-	-	-	peptidase
CPLHMICO_01593	3.2e-173	-	-	-	V	-	-	-	ABC-2 type transporter
CPLHMICO_01594	5.43e-166	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CPLHMICO_01595	3.87e-63	-	-	-	KLT	-	-	-	Protein kinase domain
CPLHMICO_01596	2.91e-154	-	-	-	-	-	-	-	-
CPLHMICO_01598	9.25e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CPLHMICO_01599	2.79e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
CPLHMICO_01600	5.85e-133	-	-	-	S	ko:K06872	-	ko00000	TPM domain
CPLHMICO_01601	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
CPLHMICO_01602	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPLHMICO_01603	5.49e-191	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CPLHMICO_01604	3.34e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CPLHMICO_01605	3.27e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CPLHMICO_01606	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CPLHMICO_01607	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CPLHMICO_01608	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPLHMICO_01609	3.49e-61	-	-	-	-	-	-	-	-
CPLHMICO_01610	1.27e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPLHMICO_01611	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CPLHMICO_01612	1.73e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CPLHMICO_01613	3.45e-91	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CPLHMICO_01614	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CPLHMICO_01615	1.26e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPLHMICO_01616	3.27e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CPLHMICO_01617	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CPLHMICO_01618	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CPLHMICO_01619	3.58e-93	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CPLHMICO_01620	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPLHMICO_01621	9.02e-163	-	-	-	S	-	-	-	(CBS) domain
CPLHMICO_01622	5.2e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CPLHMICO_01623	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPLHMICO_01624	1.48e-45	yabO	-	-	J	-	-	-	S4 domain protein
CPLHMICO_01625	1.99e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CPLHMICO_01626	4.32e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
CPLHMICO_01627	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CPLHMICO_01628	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPLHMICO_01629	2.85e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CPLHMICO_01630	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01631	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CPLHMICO_01632	1.09e-251	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPLHMICO_01633	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CPLHMICO_01635	5.68e-149	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
CPLHMICO_01637	4.18e-31	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
CPLHMICO_01638	2.2e-272	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
CPLHMICO_01639	3.88e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
CPLHMICO_01643	9.11e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
CPLHMICO_01644	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CPLHMICO_01647	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPLHMICO_01648	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPLHMICO_01650	1.83e-09	-	-	-	S	-	-	-	hydrolase
CPLHMICO_01651	3.01e-11	-	-	-	Q	-	-	-	phosphatase activity
CPLHMICO_01652	2.96e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPLHMICO_01653	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CPLHMICO_01654	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPLHMICO_01655	1.55e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CPLHMICO_01656	3.42e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPLHMICO_01657	6.65e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CPLHMICO_01658	1.72e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CPLHMICO_01659	2.82e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPLHMICO_01660	1.79e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CPLHMICO_01661	3.7e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CPLHMICO_01662	3.28e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CPLHMICO_01663	8.89e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CPLHMICO_01664	9.34e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CPLHMICO_01665	1.34e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CPLHMICO_01666	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CPLHMICO_01667	5.64e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPLHMICO_01668	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CPLHMICO_01669	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPLHMICO_01670	2.92e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPLHMICO_01671	1.55e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CPLHMICO_01672	4.52e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CPLHMICO_01673	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CPLHMICO_01674	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CPLHMICO_01675	5.33e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CPLHMICO_01676	6.92e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CPLHMICO_01677	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CPLHMICO_01678	5.08e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPLHMICO_01679	6.6e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CPLHMICO_01680	2.66e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPLHMICO_01681	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CPLHMICO_01682	2.32e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CPLHMICO_01683	1.41e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CPLHMICO_01684	4.28e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CPLHMICO_01685	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CPLHMICO_01686	8.89e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPLHMICO_01687	9.68e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CPLHMICO_01688	3.35e-28	-	-	-	-	-	-	-	-
CPLHMICO_01689	7.94e-33	-	-	-	-	-	-	-	-
CPLHMICO_01690	2.35e-43	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01691	3.05e-146	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01692	6.56e-16	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01693	1.23e-49	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CPLHMICO_01694	3.79e-91	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CPLHMICO_01695	4.19e-64	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_01696	3.32e-63	-	-	-	EGP	-	-	-	Major Facilitator
CPLHMICO_01697	1.8e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CPLHMICO_01700	4.22e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CPLHMICO_01701	3.07e-225	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CPLHMICO_01705	1.75e-125	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01706	7.13e-128	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CPLHMICO_01707	6.54e-273	-	-	-	-	-	-	-	-
CPLHMICO_01708	3.41e-256	-	-	-	-	-	-	-	-
CPLHMICO_01709	2.79e-162	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
CPLHMICO_01710	2.52e-286	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CPLHMICO_01711	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CPLHMICO_01712	1.19e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CPLHMICO_01713	1.51e-260	-	-	-	M	-	-	-	Glycosyl transferases group 1
CPLHMICO_01714	4.17e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
CPLHMICO_01715	2.23e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CPLHMICO_01716	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CPLHMICO_01719	4.54e-138	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CPLHMICO_01720	1.42e-117	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CPLHMICO_01721	2.28e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CPLHMICO_01722	6.12e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
CPLHMICO_01723	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CPLHMICO_01724	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPLHMICO_01725	1.98e-259	camS	-	-	S	-	-	-	sex pheromone
CPLHMICO_01726	3.99e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CPLHMICO_01727	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CPLHMICO_01728	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CPLHMICO_01729	5.36e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CPLHMICO_01730	2.18e-158	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CPLHMICO_01731	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPLHMICO_01732	2.13e-189	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
CPLHMICO_01733	3.59e-154	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
CPLHMICO_01734	3.6e-39	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_01735	2.47e-52	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_01736	3.29e-76	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CPLHMICO_01737	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CPLHMICO_01738	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
CPLHMICO_01739	3.32e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CPLHMICO_01740	6.09e-144	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
CPLHMICO_01741	3.1e-305	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CPLHMICO_01742	6.93e-161	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
CPLHMICO_01743	4.06e-123	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
CPLHMICO_01744	1.04e-135	-	-	-	T	-	-	-	Gaf domain
CPLHMICO_01745	1.13e-11	-	-	-	T	-	-	-	GGDEF domain
CPLHMICO_01747	1.17e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CPLHMICO_01748	2.21e-69	-	-	-	S	ko:K08987	-	ko00000	membrane
CPLHMICO_01749	3.25e-112	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
CPLHMICO_01750	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CPLHMICO_01751	9.32e-70	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
CPLHMICO_01752	4.6e-10	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CPLHMICO_01753	4.27e-85	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CPLHMICO_01754	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CPLHMICO_01755	2.34e-215	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CPLHMICO_01756	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CPLHMICO_01757	2.07e-111	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
CPLHMICO_01759	1.27e-74	-	-	-	-	-	-	-	-
CPLHMICO_01760	9.06e-17	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
CPLHMICO_01761	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_01762	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CPLHMICO_01763	3.6e-266	-	-	-	-	-	-	-	-
CPLHMICO_01765	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CPLHMICO_01766	1.06e-166	-	-	-	-	-	-	-	-
CPLHMICO_01767	1.19e-183	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
CPLHMICO_01768	2.81e-16	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
CPLHMICO_01769	3.38e-12	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CPLHMICO_01770	9.32e-247	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CPLHMICO_01771	1.54e-219	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CPLHMICO_01772	4.37e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CPLHMICO_01773	3.87e-282	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
CPLHMICO_01774	3.15e-126	-	-	-	S	-	-	-	Membrane
CPLHMICO_01775	6.36e-67	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CPLHMICO_01776	3.33e-111	ydiN	-	-	C	ko:K03762	-	ko00000,ko02000	succinate dehydrogenase
CPLHMICO_01777	6.06e-222	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CPLHMICO_01778	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CPLHMICO_01779	9.24e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
CPLHMICO_01780	9.99e-127	-	-	-	M	-	-	-	Glycosyl transferase family 8
CPLHMICO_01781	1.25e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
CPLHMICO_01782	1.07e-192	-	-	-	I	-	-	-	Acyl-transferase
CPLHMICO_01784	3.81e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CPLHMICO_01785	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CPLHMICO_01786	0.0	yycH	-	-	S	-	-	-	YycH protein
CPLHMICO_01787	3.96e-183	yycI	-	-	S	-	-	-	YycH protein
CPLHMICO_01788	2.61e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CPLHMICO_01789	1.29e-239	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CPLHMICO_01790	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CPLHMICO_01795	5.35e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CPLHMICO_01796	1.86e-286	-	-	-	S	-	-	-	Membrane
CPLHMICO_01797	8.99e-61	-	-	-	-	-	-	-	-
CPLHMICO_01798	0.000111	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CPLHMICO_01799	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CPLHMICO_01800	1.36e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CPLHMICO_01801	1.12e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CPLHMICO_01802	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CPLHMICO_01804	1.01e-86	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CPLHMICO_01805	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CPLHMICO_01806	2.95e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CPLHMICO_01807	2.08e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
CPLHMICO_01808	1.33e-150	dltr	-	-	K	-	-	-	response regulator
CPLHMICO_01809	6.84e-293	sptS	-	-	T	-	-	-	Histidine kinase
CPLHMICO_01810	2.36e-248	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CPLHMICO_01811	4.87e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CPLHMICO_01812	6.16e-282	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CPLHMICO_01813	1.89e-309	-	-	-	S	-	-	-	Putative threonine/serine exporter
CPLHMICO_01814	1.16e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPLHMICO_01815	2.28e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CPLHMICO_01816	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPLHMICO_01817	2.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CPLHMICO_01818	8.64e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CPLHMICO_01819	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CPLHMICO_01820	5.5e-50	-	-	-	-	-	-	-	-
CPLHMICO_01821	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CPLHMICO_01822	2.13e-235	ydbI	-	-	K	-	-	-	AI-2E family transporter
CPLHMICO_01823	2.37e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPLHMICO_01824	1.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPLHMICO_01825	3.83e-230	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CPLHMICO_01826	1.53e-158	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CPLHMICO_01827	1.87e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CPLHMICO_01828	1.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CPLHMICO_01829	6.26e-101	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CPLHMICO_01830	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CPLHMICO_01831	2.63e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPLHMICO_01832	7.4e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CPLHMICO_01833	1.05e-162	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CPLHMICO_01834	5.91e-158	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CPLHMICO_01835	9.71e-65	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
CPLHMICO_01838	5.43e-183	-	-	-	G	-	-	-	polysaccharide deacetylase
CPLHMICO_01839	9.05e-62	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CPLHMICO_01840	5.71e-216	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CPLHMICO_01841	9.01e-06	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CPLHMICO_01842	3.39e-118	yliE	-	-	T	-	-	-	EAL domain
CPLHMICO_01843	1.02e-195	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
CPLHMICO_01844	1.64e-120	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CPLHMICO_01845	6.42e-229	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
CPLHMICO_01846	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
CPLHMICO_01847	7.34e-208	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
CPLHMICO_01848	2.5e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CPLHMICO_01849	1.81e-109	-	-	-	K	-	-	-	DNA-templated transcription, initiation
CPLHMICO_01851	3.54e-180	-	-	-	-	-	-	-	-
CPLHMICO_01853	4.63e-59	yliE	-	-	T	-	-	-	EAL domain
CPLHMICO_01854	5.3e-40	scrK	2.7.1.2, 2.7.1.4	-	GK	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CPLHMICO_01855	7.3e-248	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CPLHMICO_01856	1.13e-40	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity