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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IIGHNGHN_00002	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IIGHNGHN_00003	4.49e-29	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IIGHNGHN_00004	1.18e-59	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IIGHNGHN_00005	7.66e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
IIGHNGHN_00006	4.45e-124	-	-	-	GM	-	-	-	Male sterility protein
IIGHNGHN_00007	9.61e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_00008	7.48e-15	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIGHNGHN_00010	2.29e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGHNGHN_00011	7.6e-95	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00012	2.43e-59	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IIGHNGHN_00013	5.49e-132	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IIGHNGHN_00014	2.18e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
IIGHNGHN_00015	1.15e-104	-	-	-	-	-	-	-	-
IIGHNGHN_00016	9.3e-272	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGHNGHN_00017	2.42e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IIGHNGHN_00018	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IIGHNGHN_00019	1.51e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIGHNGHN_00020	7.49e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IIGHNGHN_00021	2.79e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IIGHNGHN_00022	1.53e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IIGHNGHN_00023	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IIGHNGHN_00024	1.53e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IIGHNGHN_00025	8.51e-267	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IIGHNGHN_00026	1.09e-158	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
IIGHNGHN_00027	6.41e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_00028	1.09e-79	-	-	-	P	-	-	-	Rhodanese Homology Domain
IIGHNGHN_00029	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IIGHNGHN_00030	1.36e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIGHNGHN_00031	3.79e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IIGHNGHN_00032	7e-52	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIGHNGHN_00034	1.98e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IIGHNGHN_00035	1.99e-87	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IIGHNGHN_00036	5.02e-310	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IIGHNGHN_00037	1.17e-38	-	-	-	-	-	-	-	-
IIGHNGHN_00038	8.5e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IIGHNGHN_00039	2.74e-71	-	-	-	-	-	-	-	-
IIGHNGHN_00040	3.56e-160	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIGHNGHN_00041	7.14e-111	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00042	1.03e-143	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IIGHNGHN_00043	7.55e-265	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
IIGHNGHN_00044	1.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IIGHNGHN_00045	1.53e-74	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IIGHNGHN_00046	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IIGHNGHN_00047	7.74e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIGHNGHN_00048	1.88e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGHNGHN_00049	6.85e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIGHNGHN_00050	1.15e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IIGHNGHN_00051	0.0	pyrAB2	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IIGHNGHN_00052	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IIGHNGHN_00053	2.12e-92	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00054	5.8e-248	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
IIGHNGHN_00055	1.82e-295	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
IIGHNGHN_00056	2.42e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
IIGHNGHN_00057	1.61e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IIGHNGHN_00058	2.03e-96	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IIGHNGHN_00059	4.51e-107	ysaA	-	-	V	-	-	-	VanZ like family
IIGHNGHN_00060	9.21e-120	-	-	-	V	-	-	-	VanZ like family
IIGHNGHN_00061	3.56e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIGHNGHN_00063	2.08e-22	-	-	-	-	-	-	-	-
IIGHNGHN_00064	4.48e-159	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
IIGHNGHN_00065	2.66e-157	-	-	-	Q	-	-	-	Methyltransferase domain
IIGHNGHN_00066	1.19e-62	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGHNGHN_00067	1.09e-75	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGHNGHN_00068	2.2e-156	yneE	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00069	5.94e-112	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00070	1.58e-63	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IIGHNGHN_00071	2.21e-139	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGHNGHN_00072	2.45e-180	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IIGHNGHN_00073	3.98e-153	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGHNGHN_00074	3.27e-121	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGHNGHN_00075	2.98e-75	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IIGHNGHN_00076	1.55e-56	-	-	-	I	-	-	-	sulfurtransferase activity
IIGHNGHN_00077	2.63e-184	-	-	-	S	-	-	-	membrane
IIGHNGHN_00078	6.62e-33	-	-	-	S	-	-	-	membrane
IIGHNGHN_00079	1.84e-53	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00080	2.32e-16	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00081	3.83e-257	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IIGHNGHN_00082	6.52e-98	rppH3	-	-	F	-	-	-	NUDIX domain
IIGHNGHN_00083	1.83e-128	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIGHNGHN_00084	1e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IIGHNGHN_00085	4.21e-125	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IIGHNGHN_00086	2.75e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IIGHNGHN_00087	4.34e-235	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00088	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIGHNGHN_00089	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIGHNGHN_00090	5.45e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIGHNGHN_00091	1.73e-214	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IIGHNGHN_00092	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IIGHNGHN_00093	1.68e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IIGHNGHN_00094	2.39e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IIGHNGHN_00095	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIGHNGHN_00096	1.37e-214	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IIGHNGHN_00097	4.15e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIGHNGHN_00098	8.11e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIGHNGHN_00099	7.59e-87	abiGI	-	-	K	-	-	-	Psort location Cytoplasmic, score
IIGHNGHN_00100	4.45e-158	-	-	-	-	-	-	-	-
IIGHNGHN_00101	6.56e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IIGHNGHN_00102	1.11e-133	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IIGHNGHN_00103	7.18e-206	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IIGHNGHN_00104	8.63e-191	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IIGHNGHN_00105	1.06e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IIGHNGHN_00106	3.37e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIGHNGHN_00107	2.73e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIGHNGHN_00108	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00109	3.17e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIGHNGHN_00110	8.9e-219	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIGHNGHN_00111	2.49e-295	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IIGHNGHN_00112	4.58e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIGHNGHN_00113	2.29e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IIGHNGHN_00114	5.63e-279	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IIGHNGHN_00115	9.33e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IIGHNGHN_00116	4.96e-60	-	-	-	M	-	-	-	Lysin motif
IIGHNGHN_00117	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IIGHNGHN_00118	1.71e-239	-	-	-	S	-	-	-	Helix-turn-helix domain
IIGHNGHN_00119	2.14e-119	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIGHNGHN_00120	1.05e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIGHNGHN_00121	1.7e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIGHNGHN_00122	5.16e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIGHNGHN_00123	7.96e-94	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIGHNGHN_00124	3.45e-209	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IIGHNGHN_00125	1.26e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IIGHNGHN_00126	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IIGHNGHN_00127	2.96e-157	tal2	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
IIGHNGHN_00128	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IIGHNGHN_00129	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIGHNGHN_00130	3.57e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IIGHNGHN_00131	1.7e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIGHNGHN_00132	3.96e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IIGHNGHN_00133	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IIGHNGHN_00134	3.46e-115	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00135	9.66e-252	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIGHNGHN_00136	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIGHNGHN_00137	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IIGHNGHN_00138	7.13e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IIGHNGHN_00139	8.77e-193	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IIGHNGHN_00140	1.27e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIGHNGHN_00141	6.73e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IIGHNGHN_00142	1.22e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIGHNGHN_00143	1.19e-231	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IIGHNGHN_00144	1.72e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IIGHNGHN_00145	4.17e-89	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGHNGHN_00146	6.29e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IIGHNGHN_00147	2.21e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IIGHNGHN_00148	2.4e-193	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IIGHNGHN_00149	1e-218	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IIGHNGHN_00150	3.08e-308	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
IIGHNGHN_00151	1.84e-194	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IIGHNGHN_00152	3.89e-259	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIGHNGHN_00153	2.73e-207	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIGHNGHN_00154	9.84e-123	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIGHNGHN_00155	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIGHNGHN_00156	5.65e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IIGHNGHN_00157	1.76e-121	-	-	-	-	-	-	-	-
IIGHNGHN_00158	1.41e-205	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IIGHNGHN_00159	5.74e-206	-	-	-	G	-	-	-	Fructosamine kinase
IIGHNGHN_00160	3.17e-149	-	-	-	S	-	-	-	HAD-hyrolase-like
IIGHNGHN_00161	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIGHNGHN_00162	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIGHNGHN_00163	8.94e-77	-	-	-	-	-	-	-	-
IIGHNGHN_00164	3.5e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIGHNGHN_00165	9.42e-232	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IIGHNGHN_00166	1.79e-71	-	-	-	-	-	-	-	-
IIGHNGHN_00167	7.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIGHNGHN_00168	6.81e-83	-	-	-	-	-	-	-	-
IIGHNGHN_00171	8.22e-37	-	-	-	-	-	-	-	-
IIGHNGHN_00172	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIGHNGHN_00173	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIGHNGHN_00174	1.02e-46	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIGHNGHN_00175	8.72e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IIGHNGHN_00176	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIGHNGHN_00177	4.77e-24	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IIGHNGHN_00178	4.22e-250	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIGHNGHN_00179	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IIGHNGHN_00180	2.51e-123	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIGHNGHN_00181	8.18e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIGHNGHN_00182	1.69e-229	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IIGHNGHN_00183	4.24e-217	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIGHNGHN_00184	1.77e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIGHNGHN_00185	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIGHNGHN_00186	4.88e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
IIGHNGHN_00187	2.64e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IIGHNGHN_00188	2.39e-247	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IIGHNGHN_00189	3.03e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IIGHNGHN_00190	4.41e-52	-	-	-	-	-	-	-	-
IIGHNGHN_00191	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIGHNGHN_00192	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIGHNGHN_00193	8.39e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IIGHNGHN_00194	1.13e-176	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IIGHNGHN_00195	3.43e-191	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIGHNGHN_00196	3.42e-97	-	-	-	-	-	-	-	-
IIGHNGHN_00197	1.91e-109	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIGHNGHN_00198	2.12e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IIGHNGHN_00199	2.79e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIGHNGHN_00200	9.38e-187	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IIGHNGHN_00201	3.29e-173	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
IIGHNGHN_00202	1.51e-236	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGHNGHN_00203	6.07e-58	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IIGHNGHN_00204	5.88e-176	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IIGHNGHN_00205	2.07e-154	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IIGHNGHN_00206	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGHNGHN_00207	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGHNGHN_00208	1.61e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IIGHNGHN_00209	4.34e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
IIGHNGHN_00210	2.41e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIGHNGHN_00211	6.78e-100	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
IIGHNGHN_00212	2.51e-108	-	-	-	-	-	-	-	-
IIGHNGHN_00213	8.64e-274	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IIGHNGHN_00214	5.48e-100	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IIGHNGHN_00215	2.87e-97	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IIGHNGHN_00216	2.82e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IIGHNGHN_00217	2.94e-34	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IIGHNGHN_00218	8.41e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IIGHNGHN_00219	6.75e-45	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IIGHNGHN_00220	7e-53	traA	-	-	L	-	-	-	MobA MobL family protein
IIGHNGHN_00221	0.0	-	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
IIGHNGHN_00222	8.23e-218	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIGHNGHN_00223	7.46e-59	-	-	-	-	-	-	-	-
IIGHNGHN_00224	3.64e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIGHNGHN_00225	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGHNGHN_00226	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIGHNGHN_00228	1.56e-145	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
IIGHNGHN_00229	4.23e-224	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
IIGHNGHN_00230	1.25e-184	-	-	-	I	-	-	-	Acyltransferase family
IIGHNGHN_00231	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
IIGHNGHN_00232	3.12e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIGHNGHN_00233	3.69e-202	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
IIGHNGHN_00235	5.84e-226	-	-	-	K	ko:K02529,ko:K03435	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIGHNGHN_00236	1.48e-69	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
IIGHNGHN_00237	1.81e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IIGHNGHN_00238	2.26e-110	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIGHNGHN_00239	1.04e-177	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IIGHNGHN_00240	0.0	norG_2	-	-	K	-	-	-	Aminotransferase class I and II
IIGHNGHN_00241	5e-92	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
IIGHNGHN_00242	2.91e-182	-	-	-	S	-	-	-	Membrane
IIGHNGHN_00243	8.46e-239	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IIGHNGHN_00244	7.37e-221	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IIGHNGHN_00245	4.85e-97	-	-	-	-	-	-	-	-
IIGHNGHN_00246	1.46e-65	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IIGHNGHN_00247	3.77e-68	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IIGHNGHN_00248	8.42e-129	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_00249	8.63e-188	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IIGHNGHN_00251	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IIGHNGHN_00252	4.99e-251	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIGHNGHN_00253	0.0	xylP2	-	-	G	-	-	-	symporter
IIGHNGHN_00254	2.48e-33	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
IIGHNGHN_00255	1.04e-41	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIGHNGHN_00256	3.74e-117	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIGHNGHN_00257	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIGHNGHN_00258	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_00259	2.08e-106	-	-	-	-	-	-	-	-
IIGHNGHN_00261	5.56e-223	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGHNGHN_00262	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIGHNGHN_00263	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IIGHNGHN_00264	3.67e-145	-	-	-	-	-	-	-	-
IIGHNGHN_00265	1.19e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_00267	1.96e-234	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IIGHNGHN_00268	2.25e-284	-	-	-	C	-	-	-	Oxidoreductase
IIGHNGHN_00270	3.41e-89	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGHNGHN_00271	5.55e-269	mccF	-	-	V	-	-	-	LD-carboxypeptidase
IIGHNGHN_00272	2.21e-225	-	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IIGHNGHN_00273	1.56e-160	-	-	-	K	ko:K16326	-	ko00000,ko03000	Cyclic nucleotide-monophosphate binding domain
IIGHNGHN_00274	4.22e-219	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIGHNGHN_00275	4.7e-283	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
IIGHNGHN_00276	9.88e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IIGHNGHN_00277	2.94e-148	-	-	-	S	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	GyrI-like small molecule binding domain
IIGHNGHN_00278	2.79e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
IIGHNGHN_00279	8.07e-128	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IIGHNGHN_00280	1.48e-284	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIGHNGHN_00281	7.71e-157	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00282	3.11e-230	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGHNGHN_00283	5.67e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00284	1e-271	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIGHNGHN_00285	2.49e-83	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
IIGHNGHN_00286	1.23e-275	-	-	-	G	-	-	-	Sugar (and other) transporter
IIGHNGHN_00287	1.29e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
IIGHNGHN_00288	1.88e-165	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IIGHNGHN_00289	1.4e-186	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
IIGHNGHN_00290	4.6e-297	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	Xylulose kinase
IIGHNGHN_00291	4.4e-210	-	-	-	-	-	-	-	-
IIGHNGHN_00292	4.54e-199	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGHNGHN_00293	2.97e-178	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIGHNGHN_00294	2.63e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
IIGHNGHN_00295	4.7e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IIGHNGHN_00296	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IIGHNGHN_00297	3.19e-208	mleR	-	-	K	-	-	-	LysR family
IIGHNGHN_00298	2.8e-189	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IIGHNGHN_00299	1.67e-275	aguA2	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
IIGHNGHN_00300	5.52e-214	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
IIGHNGHN_00301	6.05e-275	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	agmatine deiminase
IIGHNGHN_00302	2.01e-304	aguD	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino Acid
IIGHNGHN_00303	1.96e-251	ptcA	2.1.3.6	-	E	ko:K13252	-	ko00000,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIGHNGHN_00304	2.33e-262	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IIGHNGHN_00305	5.32e-36	-	-	-	-	-	-	-	-
IIGHNGHN_00306	7.16e-201	-	-	-	EG	-	-	-	EamA-like transporter family
IIGHNGHN_00307	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IIGHNGHN_00308	1.69e-290	-	-	-	M	-	-	-	domain protein
IIGHNGHN_00309	5.91e-51	-	-	-	-	-	-	-	-
IIGHNGHN_00310	2.06e-42	-	-	-	S	-	-	-	Transglycosylase associated protein
IIGHNGHN_00311	1.89e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IIGHNGHN_00312	2.41e-199	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00313	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
IIGHNGHN_00314	2.67e-38	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IIGHNGHN_00318	1.5e-177	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IIGHNGHN_00319	1.56e-139	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIGHNGHN_00320	1.52e-153	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIGHNGHN_00321	4.46e-276	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IIGHNGHN_00322	4.82e-166	-	-	-	S	-	-	-	Protein of unknown function
IIGHNGHN_00323	1.6e-219	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IIGHNGHN_00324	1.38e-196	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
IIGHNGHN_00325	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IIGHNGHN_00326	7.2e-236	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IIGHNGHN_00327	4.81e-157	-	-	-	K	-	-	-	UTRA
IIGHNGHN_00328	2.72e-48	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IIGHNGHN_00340	1.07e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIGHNGHN_00341	3.89e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIGHNGHN_00342	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIGHNGHN_00343	5.23e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IIGHNGHN_00344	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIGHNGHN_00345	4.64e-124	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IIGHNGHN_00346	9.05e-58	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IIGHNGHN_00347	7.09e-53	yabO	-	-	J	-	-	-	S4 domain protein
IIGHNGHN_00348	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IIGHNGHN_00349	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIGHNGHN_00350	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIGHNGHN_00351	5.62e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIGHNGHN_00352	3.16e-74	-	-	-	U	-	-	-	Major Facilitator Superfamily
IIGHNGHN_00353	9.19e-168	epsB	-	-	M	-	-	-	biosynthesis protein
IIGHNGHN_00354	6.12e-153	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IIGHNGHN_00355	2.15e-175	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IIGHNGHN_00356	6.28e-96	-	-	-	M	-	-	-	Bacterial sugar transferase
IIGHNGHN_00357	1.29e-57	rfbN	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IIGHNGHN_00358	7.73e-54	-	-	-	-	-	-	-	-
IIGHNGHN_00360	3.97e-56	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IIGHNGHN_00361	3.15e-56	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IIGHNGHN_00362	8.25e-112	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IIGHNGHN_00363	2.53e-186	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIGHNGHN_00364	1.32e-138	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIGHNGHN_00365	6.63e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIGHNGHN_00366	6.65e-198	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIGHNGHN_00377	5.37e-33	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IIGHNGHN_00379	4.41e-113	-	-	-	-	-	-	-	-
IIGHNGHN_00380	1.57e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IIGHNGHN_00381	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IIGHNGHN_00382	2.98e-268	xylR	-	-	GK	-	-	-	ROK family
IIGHNGHN_00383	0.0	xylP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGHNGHN_00384	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
IIGHNGHN_00385	5.26e-44	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IIGHNGHN_00386	5.29e-61	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_00388	4.7e-51	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IIGHNGHN_00389	2.84e-100	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IIGHNGHN_00390	7.84e-70	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
IIGHNGHN_00391	1.56e-75	-	-	-	-	-	-	-	-
IIGHNGHN_00392	1.08e-235	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IIGHNGHN_00393	3.66e-193	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
IIGHNGHN_00394	1.46e-126	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IIGHNGHN_00395	1.51e-164	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IIGHNGHN_00396	1.79e-39	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
IIGHNGHN_00397	2.17e-255	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IIGHNGHN_00398	6.74e-136	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
IIGHNGHN_00399	6.6e-99	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIGHNGHN_00400	4.32e-41	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IIGHNGHN_00401	3.78e-142	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IIGHNGHN_00402	2.16e-96	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGHNGHN_00403	2.62e-88	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
IIGHNGHN_00404	1.42e-164	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGHNGHN_00405	1.94e-92	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
IIGHNGHN_00406	1.39e-150	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGHNGHN_00407	1.05e-120	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
IIGHNGHN_00408	7.61e-143	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGHNGHN_00409	2.88e-81	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IIGHNGHN_00410	6.05e-78	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGHNGHN_00411	5.41e-208	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IIGHNGHN_00412	2.62e-113	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
IIGHNGHN_00413	8.25e-122	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IIGHNGHN_00414	1.45e-208	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
IIGHNGHN_00415	5.49e-112	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
IIGHNGHN_00416	1.21e-59	-	-	-	S	-	-	-	Pfam:DUF3816
IIGHNGHN_00417	3.13e-87	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
IIGHNGHN_00418	2.73e-73	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIGHNGHN_00419	2.65e-133	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IIGHNGHN_00420	7.55e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIGHNGHN_00421	1.14e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IIGHNGHN_00422	2.84e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIGHNGHN_00423	9.98e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIGHNGHN_00424	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IIGHNGHN_00425	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIGHNGHN_00426	1.03e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IIGHNGHN_00427	8.41e-67	-	-	-	-	-	-	-	-
IIGHNGHN_00428	2.81e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IIGHNGHN_00429	8.05e-231	-	-	-	-	-	-	-	-
IIGHNGHN_00430	7.91e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IIGHNGHN_00431	5.35e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGHNGHN_00432	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGHNGHN_00434	0.0	-	-	-	L	-	-	-	DNA helicase
IIGHNGHN_00435	2.83e-109	-	-	-	-	-	-	-	-
IIGHNGHN_00436	1.35e-67	-	-	-	-	-	-	-	-
IIGHNGHN_00437	5.19e-226	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIGHNGHN_00438	2.02e-113	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
IIGHNGHN_00439	9.43e-139	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase HUMPS family
IIGHNGHN_00440	3.39e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IIGHNGHN_00441	2.26e-294	gntT	-	-	EG	-	-	-	Citrate transporter
IIGHNGHN_00442	1.01e-172	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IIGHNGHN_00443	1.54e-47	-	-	-	-	-	-	-	-
IIGHNGHN_00444	2.38e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIGHNGHN_00446	2.98e-49	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IIGHNGHN_00447	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IIGHNGHN_00448	1.01e-274	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IIGHNGHN_00449	5.97e-208	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_00450	1.79e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IIGHNGHN_00451	8.08e-147	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IIGHNGHN_00452	9.14e-122	-	-	-	I	-	-	-	NUDIX domain
IIGHNGHN_00457	3.36e-91	-	-	-	S	-	-	-	TIR domain
IIGHNGHN_00458	4.03e-207	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IIGHNGHN_00459	8.06e-96	-	-	-	-	-	-	-	-
IIGHNGHN_00460	6.11e-11	-	-	-	K	-	-	-	CsbD-like
IIGHNGHN_00461	1.46e-101	-	-	-	T	-	-	-	Universal stress protein family
IIGHNGHN_00462	3.06e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIGHNGHN_00463	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IIGHNGHN_00464	2.99e-70	yrvD	-	-	S	-	-	-	Pfam:DUF1049
IIGHNGHN_00465	8.03e-229	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIGHNGHN_00467	1.02e-157	-	-	-	-	-	-	-	-
IIGHNGHN_00468	2.41e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIGHNGHN_00469	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIGHNGHN_00470	3.49e-22	-	-	-	-	-	-	-	-
IIGHNGHN_00471	4.51e-69	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IIGHNGHN_00472	9.22e-141	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IIGHNGHN_00473	5.91e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIGHNGHN_00474	1.02e-298	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIGHNGHN_00475	9.97e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIGHNGHN_00476	5.1e-212	-	-	-	S	-	-	-	Tetratricopeptide repeat
IIGHNGHN_00477	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIGHNGHN_00478	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIGHNGHN_00479	8e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IIGHNGHN_00480	2.32e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IIGHNGHN_00481	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IIGHNGHN_00482	7.41e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IIGHNGHN_00483	2e-96	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IIGHNGHN_00484	9.31e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IIGHNGHN_00485	1.43e-106	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIGHNGHN_00486	1.6e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IIGHNGHN_00487	2.3e-58	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IIGHNGHN_00488	7.3e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IIGHNGHN_00489	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IIGHNGHN_00490	6.34e-183	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IIGHNGHN_00491	4.17e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IIGHNGHN_00492	2.72e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
IIGHNGHN_00493	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IIGHNGHN_00494	2.72e-284	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIGHNGHN_00495	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IIGHNGHN_00496	4.77e-271	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IIGHNGHN_00497	9.7e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIGHNGHN_00498	5.31e-104	-	-	-	-	-	-	-	-
IIGHNGHN_00499	9.82e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IIGHNGHN_00500	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIGHNGHN_00501	1.64e-238	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
IIGHNGHN_00502	6.66e-39	-	-	-	-	-	-	-	-
IIGHNGHN_00503	6.19e-210	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IIGHNGHN_00504	6.72e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IIGHNGHN_00505	4.96e-217	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
IIGHNGHN_00506	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIGHNGHN_00507	3.56e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIGHNGHN_00508	5.43e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IIGHNGHN_00509	9.17e-241	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IIGHNGHN_00510	3.97e-201	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IIGHNGHN_00511	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_00512	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IIGHNGHN_00513	6.67e-204	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIGHNGHN_00514	6.33e-157	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_00515	3.99e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIGHNGHN_00516	4.45e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIGHNGHN_00517	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIGHNGHN_00518	3.26e-153	-	-	-	S	-	-	-	repeat protein
IIGHNGHN_00519	2.61e-155	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IIGHNGHN_00520	1.45e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIGHNGHN_00522	1.79e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IIGHNGHN_00523	6.74e-287	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIGHNGHN_00524	2.13e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIGHNGHN_00525	3.07e-44	-	-	-	-	-	-	-	-
IIGHNGHN_00526	2.49e-123	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IIGHNGHN_00527	4.08e-47	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIGHNGHN_00528	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIGHNGHN_00529	3.87e-134	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IIGHNGHN_00530	1.19e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IIGHNGHN_00531	3.42e-55	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IIGHNGHN_00532	2.58e-98	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIGHNGHN_00533	6.01e-287	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIGHNGHN_00534	7.41e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIGHNGHN_00535	1.9e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIGHNGHN_00536	1.55e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIGHNGHN_00537	1.75e-316	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIGHNGHN_00538	8.76e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIGHNGHN_00539	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIGHNGHN_00540	3.5e-79	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IIGHNGHN_00541	1.18e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIGHNGHN_00542	1.38e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IIGHNGHN_00543	1.45e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IIGHNGHN_00544	4.92e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IIGHNGHN_00545	1.62e-266	traA	-	-	L	-	-	-	MobA MobL family protein
IIGHNGHN_00546	6.38e-68	-	-	-	-	-	-	-	-
IIGHNGHN_00547	3.68e-132	-	-	-	-	-	-	-	-
IIGHNGHN_00548	1.81e-67	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
IIGHNGHN_00549	8.94e-70	-	-	-	-	-	-	-	-
IIGHNGHN_00550	4.14e-123	-	-	-	-	-	-	-	-
IIGHNGHN_00551	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
IIGHNGHN_00552	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IIGHNGHN_00553	5.85e-274	-	-	-	M	-	-	-	CHAP domain
IIGHNGHN_00554	2.06e-116	-	-	-	-	-	-	-	-
IIGHNGHN_00555	8.7e-87	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IIGHNGHN_00556	3.28e-105	-	-	-	-	-	-	-	-
IIGHNGHN_00557	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
IIGHNGHN_00558	1e-78	-	-	-	-	-	-	-	-
IIGHNGHN_00559	5.91e-199	-	-	-	-	-	-	-	-
IIGHNGHN_00560	2.08e-87	-	-	-	-	-	-	-	-
IIGHNGHN_00561	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IIGHNGHN_00562	8.83e-43	-	-	-	-	-	-	-	-
IIGHNGHN_00563	5.06e-177	-	-	-	S	-	-	-	Pfam:Arm-DNA-bind_4
IIGHNGHN_00564	3.62e-25	-	-	-	-	-	-	-	-
IIGHNGHN_00565	1.79e-23	-	-	-	-	-	-	-	-
IIGHNGHN_00569	5.73e-30	-	-	-	V	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IIGHNGHN_00570	1.46e-19	-	-	-	S	-	-	-	Pfam:Peptidase_M78
IIGHNGHN_00571	1.12e-19	-	-	-	K	-	-	-	Transcriptional
IIGHNGHN_00579	1.83e-118	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
IIGHNGHN_00580	1.39e-100	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
IIGHNGHN_00581	1.51e-44	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
IIGHNGHN_00584	1.88e-25	-	-	-	S	-	-	-	VRR_NUC
IIGHNGHN_00593	1.44e-58	-	-	-	S	-	-	-	YopX protein
IIGHNGHN_00594	6.7e-17	-	-	-	-	-	-	-	-
IIGHNGHN_00596	2.05e-64	-	-	-	Q	-	-	-	methyltransferase
IIGHNGHN_00597	1.1e-300	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IIGHNGHN_00598	7.53e-71	-	-	-	S	-	-	-	branched-chain amino acid
IIGHNGHN_00599	2.74e-174	azlC	-	-	E	-	-	-	AzlC protein
IIGHNGHN_00600	1.08e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IIGHNGHN_00601	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IIGHNGHN_00602	8.53e-42	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
IIGHNGHN_00603	1.42e-237	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
IIGHNGHN_00604	4.52e-299	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGHNGHN_00605	4.75e-268	hpk31	-	-	T	-	-	-	Histidine kinase
IIGHNGHN_00606	4.64e-159	vanR	-	-	K	-	-	-	response regulator
IIGHNGHN_00607	1.65e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIGHNGHN_00608	1.46e-51	-	-	-	-	-	-	-	-
IIGHNGHN_00609	8.96e-67	-	-	-	-	-	-	-	-
IIGHNGHN_00610	2.48e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IIGHNGHN_00611	1.62e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIGHNGHN_00612	1.15e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IIGHNGHN_00613	1.44e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIGHNGHN_00614	3.52e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IIGHNGHN_00615	3.96e-189	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIGHNGHN_00616	3.27e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IIGHNGHN_00617	8.55e-214	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
IIGHNGHN_00618	3.09e-215	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IIGHNGHN_00619	7.77e-283	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
IIGHNGHN_00620	5.15e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
IIGHNGHN_00621	1.03e-198	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
IIGHNGHN_00622	4.32e-147	-	-	-	GM	-	-	-	NmrA-like family
IIGHNGHN_00623	2.39e-59	-	-	-	-	-	-	-	-
IIGHNGHN_00624	1.85e-124	-	-	-	-	-	-	-	-
IIGHNGHN_00625	7.03e-53	-	-	-	-	-	-	-	-
IIGHNGHN_00626	2.61e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IIGHNGHN_00628	8.26e-136	-	-	-	-	-	-	-	-
IIGHNGHN_00629	1.56e-182	-	-	-	-	-	-	-	-
IIGHNGHN_00630	0.0	-	-	-	-	-	-	-	-
IIGHNGHN_00631	1.13e-24	-	-	-	-	-	-	-	-
IIGHNGHN_00632	3.32e-133	-	-	-	-	-	-	-	-
IIGHNGHN_00633	7.55e-121	-	-	-	-	-	-	-	-
IIGHNGHN_00634	2.45e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
IIGHNGHN_00635	4.39e-214	-	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_00637	9.83e-37	-	-	-	-	-	-	-	-
IIGHNGHN_00638	1.55e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IIGHNGHN_00639	2.34e-265	-	-	-	-	-	-	-	-
IIGHNGHN_00640	9.78e-75	-	-	-	-	-	-	-	-
IIGHNGHN_00641	1.76e-71	-	-	-	-	-	-	-	-
IIGHNGHN_00642	5.14e-248	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IIGHNGHN_00643	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00644	4.25e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIGHNGHN_00645	7.67e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIGHNGHN_00646	6.29e-178	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIGHNGHN_00647	4.62e-188	yneD	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IIGHNGHN_00648	2.26e-166	yjkA	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IIGHNGHN_00649	6.62e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00650	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIGHNGHN_00651	8.23e-117	-	-	-	-	-	-	-	-
IIGHNGHN_00656	2.79e-42	-	-	-	-	-	-	-	-
IIGHNGHN_00658	6.4e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_00659	1.37e-102	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IIGHNGHN_00660	3.41e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
IIGHNGHN_00661	1.06e-170	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_00662	9.49e-282	xylR	-	-	GK	-	-	-	ROK family
IIGHNGHN_00663	8.78e-13	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_00664	6.9e-148	-	-	-	G	-	-	-	Cellulase (glycosyl hydrolase family 5)
IIGHNGHN_00665	7.08e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIGHNGHN_00666	6.62e-243	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
IIGHNGHN_00667	1.2e-201	-	-	-	C	-	-	-	Aldo keto reductase
IIGHNGHN_00668	1.23e-312	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIGHNGHN_00669	0.0	cpdB	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IIGHNGHN_00670	6.04e-158	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIGHNGHN_00671	1.75e-226	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIGHNGHN_00672	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
IIGHNGHN_00673	3.7e-96	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00674	1.08e-209	-	-	-	-	-	-	-	-
IIGHNGHN_00675	9.62e-248	-	-	-	S	-	-	-	DUF218 domain
IIGHNGHN_00676	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIGHNGHN_00677	1.63e-202	nanK	-	-	GK	-	-	-	ROK family
IIGHNGHN_00678	0.0	-	-	-	E	-	-	-	Amino acid permease
IIGHNGHN_00679	3.57e-144	-	-	-	-	-	-	-	-
IIGHNGHN_00680	2.41e-248	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IIGHNGHN_00682	8.5e-66	-	-	-	-	-	-	-	-
IIGHNGHN_00683	4.54e-100	-	-	-	K	ko:K06075	-	ko00000,ko03000	Winged helix DNA-binding domain
IIGHNGHN_00684	2.3e-143	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IIGHNGHN_00685	4.27e-132	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IIGHNGHN_00686	5.95e-147	-	-	-	-	-	-	-	-
IIGHNGHN_00687	2.94e-199	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIGHNGHN_00688	1.56e-108	lytE	-	-	M	-	-	-	NlpC P60 family
IIGHNGHN_00689	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IIGHNGHN_00691	1.05e-77	-	-	-	K	-	-	-	Helix-turn-helix domain
IIGHNGHN_00692	9.78e-89	-	-	-	S	-	-	-	Domain of unknown function DUF302
IIGHNGHN_00693	5.07e-56	-	-	-	S	ko:K08982	-	ko00000	membrane protein (DUF2078)
IIGHNGHN_00694	5.5e-07	-	-	-	S	ko:K08982	-	ko00000	Short C-terminal domain
IIGHNGHN_00695	1.05e-122	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IIGHNGHN_00696	1.15e-105	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
IIGHNGHN_00697	2.53e-58	-	-	-	-	-	-	-	-
IIGHNGHN_00698	1.12e-174	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IIGHNGHN_00699	9.17e-39	-	-	-	-	-	-	-	-
IIGHNGHN_00700	6.3e-222	repA	-	-	S	-	-	-	Replication initiator protein A
IIGHNGHN_00701	5.22e-37	-	-	-	-	-	-	-	-
IIGHNGHN_00702	1.89e-166	-	-	-	S	-	-	-	Fic/DOC family
IIGHNGHN_00703	2.08e-85	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IIGHNGHN_00704	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IIGHNGHN_00705	3.85e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIGHNGHN_00706	2.47e-74	-	-	-	S	-	-	-	Arsenical resistance operon trans-acting repressor ArsD
IIGHNGHN_00707	6.64e-297	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IIGHNGHN_00708	0.0	arsA	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
IIGHNGHN_00709	1.57e-75	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	Helix-turn-helix domain
IIGHNGHN_00710	3.23e-64	tnpR2	-	-	L	-	-	-	Helix-turn-helix domain of resolvase
IIGHNGHN_00711	5.35e-248	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGHNGHN_00712	1.63e-75	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IIGHNGHN_00713	6.13e-226	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IIGHNGHN_00714	4.87e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00715	9.31e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_00716	6.03e-161	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIGHNGHN_00718	6.64e-162	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IIGHNGHN_00719	1.35e-55	-	-	-	S	-	-	-	Mor transcription activator family
IIGHNGHN_00720	3.53e-52	-	-	-	S	-	-	-	Mor transcription activator family
IIGHNGHN_00721	8.58e-85	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIGHNGHN_00722	9.93e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IIGHNGHN_00723	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00724	4.38e-262	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIGHNGHN_00725	2.75e-79	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
IIGHNGHN_00726	7.3e-268	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
IIGHNGHN_00727	4.71e-135	-	-	-	-	-	-	-	-
IIGHNGHN_00728	2.09e-269	-	-	-	-	-	-	-	-
IIGHNGHN_00729	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIGHNGHN_00730	1.22e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IIGHNGHN_00731	2.96e-198	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIGHNGHN_00732	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGHNGHN_00733	0.0	potE	-	-	E	-	-	-	Amino Acid
IIGHNGHN_00734	2.07e-55	-	-	-	S	-	-	-	Alpha beta hydrolase
IIGHNGHN_00735	1.85e-176	-	-	-	K	-	-	-	Helix-turn-helix
IIGHNGHN_00736	2.11e-45	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_00737	4.62e-80	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IIGHNGHN_00738	7.16e-90	-	-	-	-	-	-	-	-
IIGHNGHN_00739	6.11e-129	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IIGHNGHN_00740	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
IIGHNGHN_00741	1.61e-228	-	-	-	C	-	-	-	Aldo/keto reductase family
IIGHNGHN_00742	1.57e-48	-	-	-	K	-	-	-	MerR, DNA binding
IIGHNGHN_00743	8.49e-107	-	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_00744	8.48e-265	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IIGHNGHN_00745	2.47e-41	-	-	-	S	-	-	-	YjbR
IIGHNGHN_00746	2.15e-116	-	-	-	S	-	-	-	DJ-1/PfpI family
IIGHNGHN_00747	4.34e-56	-	-	-	N	ko:K18843	-	ko00000,ko02048	PFAM Uncharacterised protein family UPF0150
IIGHNGHN_00748	1.95e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
IIGHNGHN_00749	3.57e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IIGHNGHN_00750	3.06e-115	entB	-	-	Q	-	-	-	Isochorismatase family
IIGHNGHN_00751	1.93e-37	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IIGHNGHN_00752	1.14e-177	-	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
IIGHNGHN_00753	1.85e-69	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IIGHNGHN_00754	3.15e-109	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IIGHNGHN_00755	1.67e-178	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIGHNGHN_00756	1.05e-171	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IIGHNGHN_00757	1.1e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IIGHNGHN_00758	9.5e-201	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIGHNGHN_00759	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IIGHNGHN_00760	1.16e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IIGHNGHN_00761	2.05e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIGHNGHN_00762	6.82e-292	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIGHNGHN_00763	2.74e-157	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IIGHNGHN_00764	4.71e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IIGHNGHN_00765	7.21e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIGHNGHN_00766	4.67e-233	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIGHNGHN_00767	2.5e-104	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00768	9.21e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIGHNGHN_00769	2.13e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIGHNGHN_00770	1.83e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IIGHNGHN_00771	3.58e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIGHNGHN_00772	6.46e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IIGHNGHN_00773	3.48e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IIGHNGHN_00774	4.23e-64	-	-	-	-	-	-	-	-
IIGHNGHN_00775	6.1e-312	-	-	-	S	-	-	-	Putative metallopeptidase domain
IIGHNGHN_00776	1.73e-269	-	-	-	S	-	-	-	associated with various cellular activities
IIGHNGHN_00777	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IIGHNGHN_00778	5.82e-281	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIGHNGHN_00779	8.53e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIGHNGHN_00780	1.52e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIGHNGHN_00781	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IIGHNGHN_00782	5.47e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIGHNGHN_00783	9.76e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIGHNGHN_00784	4.53e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIGHNGHN_00785	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIGHNGHN_00786	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IIGHNGHN_00787	1.43e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGHNGHN_00788	6.59e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IIGHNGHN_00789	6.64e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IIGHNGHN_00790	1.34e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IIGHNGHN_00791	2.64e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIGHNGHN_00792	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IIGHNGHN_00793	1.12e-164	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IIGHNGHN_00794	8.06e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIGHNGHN_00795	3.63e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIGHNGHN_00796	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIGHNGHN_00797	6.05e-272	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIGHNGHN_00798	2.53e-42	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIGHNGHN_00799	2.35e-134	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IIGHNGHN_00800	1.99e-69	-	-	-	-	-	-	-	-
IIGHNGHN_00802	2.84e-72	-	-	-	M	-	-	-	domain protein
IIGHNGHN_00803	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IIGHNGHN_00804	4.03e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIGHNGHN_00805	3.41e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IIGHNGHN_00806	2.43e-210	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIGHNGHN_00807	1.65e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIGHNGHN_00808	1.75e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIGHNGHN_00809	7.78e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIGHNGHN_00810	2.79e-97	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIGHNGHN_00811	8.9e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IIGHNGHN_00812	5.18e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIGHNGHN_00813	7.95e-250	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIGHNGHN_00814	8.46e-65	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IIGHNGHN_00815	7.92e-76	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IIGHNGHN_00816	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IIGHNGHN_00817	4.01e-122	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_00818	3.68e-125	-	-	-	S	-	-	-	Protein conserved in bacteria
IIGHNGHN_00819	7.15e-230	-	-	-	-	-	-	-	-
IIGHNGHN_00820	1.11e-201	-	-	-	-	-	-	-	-
IIGHNGHN_00821	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IIGHNGHN_00822	9.05e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IIGHNGHN_00823	1.17e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIGHNGHN_00824	1.69e-181	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IIGHNGHN_00825	1.23e-32	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IIGHNGHN_00826	1.11e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IIGHNGHN_00827	3.99e-232	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IIGHNGHN_00828	1.4e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IIGHNGHN_00829	2.79e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IIGHNGHN_00830	6.08e-125	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIGHNGHN_00831	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIGHNGHN_00832	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIGHNGHN_00833	1.1e-33	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IIGHNGHN_00834	0.0	-	-	-	S	-	-	-	membrane
IIGHNGHN_00835	8.94e-75	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IIGHNGHN_00836	6.68e-93	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIGHNGHN_00837	5.67e-155	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IIGHNGHN_00838	2.53e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIGHNGHN_00839	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIGHNGHN_00840	1.45e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIGHNGHN_00841	1.03e-88	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGHNGHN_00842	8.56e-119	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIGHNGHN_00843	5.03e-181	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIGHNGHN_00844	3.93e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IIGHNGHN_00845	3.4e-185	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIGHNGHN_00846	1.66e-92	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IIGHNGHN_00847	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIGHNGHN_00848	3.25e-154	csrR	-	-	K	-	-	-	response regulator
IIGHNGHN_00849	4.42e-248	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGHNGHN_00850	6.57e-144	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
IIGHNGHN_00851	7.62e-68	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IIGHNGHN_00852	1.33e-187	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
IIGHNGHN_00853	4.39e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IIGHNGHN_00854	4.1e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IIGHNGHN_00855	3.52e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IIGHNGHN_00856	2.15e-182	yqeM	-	-	Q	-	-	-	Methyltransferase
IIGHNGHN_00857	1.28e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIGHNGHN_00858	5.34e-140	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IIGHNGHN_00859	1.58e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIGHNGHN_00860	2.58e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IIGHNGHN_00861	1.24e-282	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IIGHNGHN_00862	2.6e-134	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IIGHNGHN_00863	8.55e-142	-	-	-	S	-	-	-	regulation of response to stimulus
IIGHNGHN_00864	6.09e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIGHNGHN_00865	2.41e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IIGHNGHN_00866	2.31e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIGHNGHN_00867	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIGHNGHN_00868	1.65e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IIGHNGHN_00869	5.44e-311	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IIGHNGHN_00870	4.94e-114	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIGHNGHN_00871	1.45e-143	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIGHNGHN_00872	6.74e-210	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIGHNGHN_00873	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIGHNGHN_00874	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IIGHNGHN_00875	3.59e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
IIGHNGHN_00876	4.23e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IIGHNGHN_00877	1.33e-169	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIGHNGHN_00878	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IIGHNGHN_00879	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IIGHNGHN_00881	2.17e-62	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IIGHNGHN_00883	2.88e-111	ykuL	-	-	S	-	-	-	(CBS) domain
IIGHNGHN_00884	1.78e-128	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IIGHNGHN_00885	2.53e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIGHNGHN_00886	4.82e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IIGHNGHN_00887	7.2e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IIGHNGHN_00888	6.22e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIGHNGHN_00889	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIGHNGHN_00890	4.45e-116	cvpA	-	-	S	-	-	-	Colicin V production protein
IIGHNGHN_00891	4.64e-53	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIGHNGHN_00892	2.47e-68	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IIGHNGHN_00893	7.07e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIGHNGHN_00894	5.58e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IIGHNGHN_00895	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIGHNGHN_00896	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIGHNGHN_00897	3.17e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IIGHNGHN_00898	1.35e-231	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIGHNGHN_00899	6.65e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIGHNGHN_00900	6.46e-290	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIGHNGHN_00901	5.63e-254	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIGHNGHN_00902	2.25e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIGHNGHN_00903	1.11e-139	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIGHNGHN_00904	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIGHNGHN_00905	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIGHNGHN_00906	8.08e-191	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
IIGHNGHN_00907	1.93e-313	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IIGHNGHN_00909	3.34e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIGHNGHN_00910	3e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IIGHNGHN_00911	5.53e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIGHNGHN_00912	6.04e-147	ymfM	-	-	S	ko:K15539	-	ko00000	Domain of unknown function (DUF4115)
IIGHNGHN_00913	5.18e-309	ymfH	-	-	S	-	-	-	Peptidase M16
IIGHNGHN_00914	1.25e-301	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IIGHNGHN_00915	2.52e-202	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIGHNGHN_00916	3.53e-120	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00917	5.65e-143	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGHNGHN_00918	1.57e-190	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IIGHNGHN_00919	8.3e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IIGHNGHN_00920	3.85e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IIGHNGHN_00921	1.53e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IIGHNGHN_00922	1.71e-218	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IIGHNGHN_00923	9.77e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IIGHNGHN_00924	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIGHNGHN_00925	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIGHNGHN_00926	2.34e-118	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIGHNGHN_00927	1.27e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIGHNGHN_00928	3.96e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIGHNGHN_00929	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIGHNGHN_00930	7.76e-108	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IIGHNGHN_00931	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIGHNGHN_00932	6.78e-81	-	-	-	KLT	-	-	-	serine threonine protein kinase
IIGHNGHN_00933	1.17e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IIGHNGHN_00934	1.85e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IIGHNGHN_00935	1.11e-301	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIGHNGHN_00936	2.13e-54	-	-	-	-	-	-	-	-
IIGHNGHN_00937	2.12e-107	uspA	-	-	T	-	-	-	universal stress protein
IIGHNGHN_00938	1.44e-162	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_00939	5.71e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_00940	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IIGHNGHN_00941	5.43e-277	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IIGHNGHN_00942	7.41e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IIGHNGHN_00943	1.03e-181	-	-	-	O	-	-	-	Band 7 protein
IIGHNGHN_00944	2.71e-66	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
IIGHNGHN_00945	4.52e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IIGHNGHN_00946	9.66e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IIGHNGHN_00947	1.11e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IIGHNGHN_00948	6.85e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IIGHNGHN_00949	1.13e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIGHNGHN_00950	2.25e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IIGHNGHN_00951	6.38e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IIGHNGHN_00952	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIGHNGHN_00953	8.79e-208	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIGHNGHN_00954	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIGHNGHN_00955	4.44e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIGHNGHN_00956	3.81e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIGHNGHN_00957	7.38e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIGHNGHN_00958	1.55e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IIGHNGHN_00959	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIGHNGHN_00960	3.01e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIGHNGHN_00961	4.54e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIGHNGHN_00962	8.75e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIGHNGHN_00963	6.51e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIGHNGHN_00964	7.63e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IIGHNGHN_00965	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
IIGHNGHN_00966	1.76e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IIGHNGHN_00967	8.25e-249	ampC	-	-	V	-	-	-	Beta-lactamase
IIGHNGHN_00968	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IIGHNGHN_00969	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_00970	5.22e-75	-	-	-	-	-	-	-	-
IIGHNGHN_00971	5.55e-29	-	-	-	-	-	-	-	-
IIGHNGHN_00972	1.37e-30	-	-	-	T	-	-	-	diguanylate cyclase
IIGHNGHN_00973	2.38e-130	-	-	-	T	-	-	-	diguanylate cyclase
IIGHNGHN_00974	1.06e-155	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IIGHNGHN_00975	5.37e-250	ysdE	-	-	P	-	-	-	Citrate transporter
IIGHNGHN_00976	4.6e-12	-	-	-	-	-	-	-	-
IIGHNGHN_00977	1.61e-70	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGHNGHN_00978	3.04e-86	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGHNGHN_00979	1.71e-33	-	-	-	-	-	-	-	-
IIGHNGHN_00980	2.33e-92	-	-	-	-	-	-	-	-
IIGHNGHN_00981	9.29e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
IIGHNGHN_00982	3.37e-249	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IIGHNGHN_00985	4.51e-38	-	-	-	-	-	-	-	-
IIGHNGHN_00987	1.35e-46	-	-	-	-	-	-	-	-
IIGHNGHN_00989	7.73e-56	-	-	-	-	-	-	-	-
IIGHNGHN_00991	3.98e-57	-	-	-	S	-	-	-	Baseplate J-like protein
IIGHNGHN_00995	1.36e-09	-	-	-	-	-	-	-	-
IIGHNGHN_00996	6.99e-15	-	-	-	M	-	-	-	LysM domain
IIGHNGHN_00997	5.36e-227	-	-	-	M	-	-	-	tape measure
IIGHNGHN_01008	4.5e-174	-	-	-	S	-	-	-	Phage major capsid protein E
IIGHNGHN_01009	9.68e-58	-	-	-	-	-	-	-	-
IIGHNGHN_01010	6.25e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
IIGHNGHN_01012	1.8e-107	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
IIGHNGHN_01013	2.12e-241	-	-	-	S	-	-	-	Phage portal protein
IIGHNGHN_01014	5.7e-240	-	-	-	S	-	-	-	Terminase-like family
IIGHNGHN_01015	1.77e-37	-	-	-	S	-	-	-	DNA packaging
IIGHNGHN_01023	3.2e-08	-	-	-	-	-	-	-	-
IIGHNGHN_01031	5.71e-121	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IIGHNGHN_01032	4.82e-94	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
IIGHNGHN_01033	1.17e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIGHNGHN_01034	2.63e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
IIGHNGHN_01035	9.81e-157	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IIGHNGHN_01036	3.99e-11	-	-	-	K	-	-	-	transcriptional regulator (MerR family)
IIGHNGHN_01037	3.78e-80	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGHNGHN_01038	3.36e-140	ytbE	-	-	C	-	-	-	Aldo keto reductase
IIGHNGHN_01039	2.79e-182	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
IIGHNGHN_01040	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIGHNGHN_01041	2.51e-225	-	-	-	M	-	-	-	domain protein
IIGHNGHN_01042	5.82e-94	-	-	-	M	-	-	-	domain protein
IIGHNGHN_01043	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01044	7.91e-118	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IIGHNGHN_01045	5.96e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IIGHNGHN_01046	1.83e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIGHNGHN_01047	1.21e-130	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IIGHNGHN_01048	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIGHNGHN_01049	6.48e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIGHNGHN_01050	3.3e-199	yeaE	-	-	S	-	-	-	Aldo keto
IIGHNGHN_01051	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIGHNGHN_01052	2.16e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIGHNGHN_01053	6.93e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IIGHNGHN_01054	7.17e-99	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
IIGHNGHN_01056	5.33e-103	-	-	-	-	-	-	-	-
IIGHNGHN_01057	7.38e-61	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IIGHNGHN_01058	1.07e-217	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IIGHNGHN_01059	1.21e-216	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IIGHNGHN_01060	1.68e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IIGHNGHN_01061	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01062	8.01e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01063	2.37e-168	-	-	-	-	-	-	-	-
IIGHNGHN_01064	7.14e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IIGHNGHN_01065	2.45e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIGHNGHN_01066	2.78e-73	-	-	-	-	-	-	-	-
IIGHNGHN_01067	3.9e-82	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIGHNGHN_01068	2.7e-199	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IIGHNGHN_01070	2.04e-61	-	-	-	V	-	-	-	ABC transporter transmembrane region
IIGHNGHN_01071	1e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IIGHNGHN_01072	5.95e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIGHNGHN_01073	5.75e-93	-	-	-	K	-	-	-	LytTr DNA-binding domain
IIGHNGHN_01074	2.26e-154	-	-	-	S	-	-	-	membrane
IIGHNGHN_01076	3.44e-139	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IIGHNGHN_01078	1.63e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IIGHNGHN_01079	8.53e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIGHNGHN_01080	7.88e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IIGHNGHN_01081	9.05e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIGHNGHN_01082	2.84e-316	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIGHNGHN_01084	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIGHNGHN_01085	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIGHNGHN_01086	4.83e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
IIGHNGHN_01087	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIGHNGHN_01088	4.3e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIGHNGHN_01089	1.18e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01090	6e-130	-	-	-	-	-	-	-	-
IIGHNGHN_01091	3.18e-180	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIGHNGHN_01092	4.63e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IIGHNGHN_01093	7.73e-109	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IIGHNGHN_01094	2.61e-112	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_01095	3.35e-246	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IIGHNGHN_01096	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIGHNGHN_01097	2.33e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IIGHNGHN_01098	2.34e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IIGHNGHN_01099	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGHNGHN_01100	1.34e-158	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
IIGHNGHN_01101	5.67e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIGHNGHN_01102	1.32e-193	ybbR	-	-	S	-	-	-	YbbR-like protein
IIGHNGHN_01103	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIGHNGHN_01104	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIGHNGHN_01105	3.46e-18	-	-	-	-	-	-	-	-
IIGHNGHN_01106	1.05e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIGHNGHN_01107	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIGHNGHN_01108	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IIGHNGHN_01109	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
IIGHNGHN_01110	4.41e-289	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIGHNGHN_01111	7.94e-128	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
IIGHNGHN_01112	1.64e-74	-	-	-	-	-	-	-	-
IIGHNGHN_01113	2.3e-142	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGHNGHN_01114	6.38e-59	-	-	-	-	-	-	-	-
IIGHNGHN_01115	1.62e-77	-	-	-	K	-	-	-	Helix-turn-helix domain
IIGHNGHN_01117	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIGHNGHN_01118	2.48e-91	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01119	4.58e-100	-	-	-	S	ko:K02348	-	ko00000	Gnat family
IIGHNGHN_01122	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIGHNGHN_01123	1.68e-190	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
IIGHNGHN_01124	0.0	-	-	-	M	-	-	-	MucBP domain
IIGHNGHN_01125	2.57e-94	-	-	-	-	-	-	-	-
IIGHNGHN_01126	1.72e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IIGHNGHN_01127	2.73e-283	-	-	-	LO	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IIGHNGHN_01128	5.07e-150	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IIGHNGHN_01130	7.16e-134	-	-	-	-	-	-	-	-
IIGHNGHN_01131	9.33e-144	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IIGHNGHN_01132	2.74e-159	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIGHNGHN_01133	7.5e-72	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIGHNGHN_01134	9.85e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
IIGHNGHN_01135	1.78e-174	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_01136	0.0	-	-	-	G	-	-	-	Right handed beta helix region
IIGHNGHN_01137	1.9e-264	-	-	-	G	-	-	-	Major Facilitator
IIGHNGHN_01139	1.32e-291	-	-	-	EK	-	-	-	Aminotransferase, class I
IIGHNGHN_01140	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IIGHNGHN_01141	5.92e-164	-	-	-	F	-	-	-	glutamine amidotransferase
IIGHNGHN_01142	2.5e-17	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IIGHNGHN_01145	2.22e-296	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IIGHNGHN_01146	4.54e-100	-	-	-	T	-	-	-	Universal stress protein family
IIGHNGHN_01148	5.16e-290	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IIGHNGHN_01149	2.34e-241	mocA	-	-	S	-	-	-	Oxidoreductase
IIGHNGHN_01150	2.89e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IIGHNGHN_01151	4.47e-178	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IIGHNGHN_01152	1.09e-190	gntR	-	-	K	-	-	-	rpiR family
IIGHNGHN_01153	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IIGHNGHN_01154	1.8e-291	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IIGHNGHN_01155	4.23e-304	-	-	-	E	ko:K03294	-	ko00000	amino acid
IIGHNGHN_01156	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IIGHNGHN_01157	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IIGHNGHN_01158	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIGHNGHN_01159	1.04e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
IIGHNGHN_01160	1.37e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
IIGHNGHN_01161	2.05e-165	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IIGHNGHN_01162	2.68e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIGHNGHN_01163	1.05e-155	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIGHNGHN_01164	1.27e-50	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_01165	3.68e-77	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGHNGHN_01166	9.39e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
IIGHNGHN_01167	1.79e-246	namA	-	-	C	-	-	-	Oxidoreductase
IIGHNGHN_01168	2.96e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
IIGHNGHN_01169	1.15e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIGHNGHN_01170	1.87e-269	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
IIGHNGHN_01171	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IIGHNGHN_01172	2.89e-105	pduO	-	-	S	-	-	-	Haem-degrading
IIGHNGHN_01173	1.04e-134	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
IIGHNGHN_01174	3.64e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
IIGHNGHN_01175	7.49e-117	-	-	-	S	-	-	-	Putative propanediol utilisation
IIGHNGHN_01176	4.18e-147	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
IIGHNGHN_01177	3.38e-56	pduJ	-	-	CQ	-	-	-	BMC
IIGHNGHN_01178	8.27e-111	-	-	-	CQ	-	-	-	BMC
IIGHNGHN_01179	9.81e-77	pduH	-	-	S	-	-	-	Dehydratase medium subunit
IIGHNGHN_01180	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
IIGHNGHN_01181	7.77e-120	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
IIGHNGHN_01182	3.39e-166	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
IIGHNGHN_01183	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
IIGHNGHN_01184	6.34e-166	pduB	-	-	E	-	-	-	BMC
IIGHNGHN_01185	1.47e-55	-	-	-	CQ	-	-	-	BMC
IIGHNGHN_01186	1.71e-264	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_01187	7.75e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IIGHNGHN_01188	1.18e-56	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
IIGHNGHN_01189	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIGHNGHN_01190	1.76e-234	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IIGHNGHN_01191	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIGHNGHN_01192	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIGHNGHN_01193	4.8e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIGHNGHN_01194	1.1e-256	camS	-	-	S	-	-	-	sex pheromone
IIGHNGHN_01195	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIGHNGHN_01196	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IIGHNGHN_01197	1.01e-273	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIGHNGHN_01198	2.26e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIGHNGHN_01199	2.24e-207	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IIGHNGHN_01200	5e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIGHNGHN_01201	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IIGHNGHN_01202	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IIGHNGHN_01203	6.5e-224	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IIGHNGHN_01204	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IIGHNGHN_01205	6.14e-232	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IIGHNGHN_01206	1.04e-182	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIGHNGHN_01207	1.58e-211	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGHNGHN_01208	1.15e-36	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIGHNGHN_01209	1.42e-109	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IIGHNGHN_01210	1.17e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IIGHNGHN_01211	7.88e-169	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IIGHNGHN_01212	8.44e-121	epsB	-	-	M	-	-	-	biosynthesis protein
IIGHNGHN_01213	1.1e-210	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGHNGHN_01214	1.71e-241	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
IIGHNGHN_01215	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIGHNGHN_01216	7.66e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IIGHNGHN_01217	2.3e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
IIGHNGHN_01218	8.55e-305	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IIGHNGHN_01219	1.21e-246	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIGHNGHN_01220	3.52e-83	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IIGHNGHN_01221	6.51e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIGHNGHN_01222	1.64e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIGHNGHN_01223	2.79e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGHNGHN_01224	2.53e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGHNGHN_01225	2.81e-194	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGHNGHN_01226	6.64e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IIGHNGHN_01227	2.1e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGHNGHN_01228	6.34e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIGHNGHN_01229	2.37e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIGHNGHN_01230	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIGHNGHN_01231	5.07e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIGHNGHN_01232	1.66e-304	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIGHNGHN_01233	1.67e-90	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIGHNGHN_01234	1.2e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IIGHNGHN_01235	3.46e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIGHNGHN_01236	8.69e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIGHNGHN_01237	1.76e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIGHNGHN_01238	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIGHNGHN_01239	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIGHNGHN_01240	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIGHNGHN_01241	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIGHNGHN_01242	3.69e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIGHNGHN_01243	3.87e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IIGHNGHN_01244	3.95e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIGHNGHN_01245	1.63e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIGHNGHN_01246	9.77e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIGHNGHN_01247	7.56e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIGHNGHN_01248	1.63e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIGHNGHN_01249	4.65e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIGHNGHN_01250	5.45e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IIGHNGHN_01251	1.19e-150	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIGHNGHN_01252	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IIGHNGHN_01253	4.64e-294	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IIGHNGHN_01254	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIGHNGHN_01255	5.89e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIGHNGHN_01256	1.46e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIGHNGHN_01257	3.3e-152	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IIGHNGHN_01258	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGHNGHN_01259	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGHNGHN_01260	4.51e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_01261	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIGHNGHN_01262	2.31e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IIGHNGHN_01271	3.64e-290	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIGHNGHN_01272	2.42e-147	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IIGHNGHN_01273	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IIGHNGHN_01275	5.08e-169	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIGHNGHN_01276	4.14e-154	-	-	-	I	-	-	-	phosphatase
IIGHNGHN_01277	2.63e-94	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IIGHNGHN_01278	1.65e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIGHNGHN_01279	1.46e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IIGHNGHN_01280	4.51e-205	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IIGHNGHN_01281	8.61e-132	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_01282	3.79e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IIGHNGHN_01283	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIGHNGHN_01284	2.07e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IIGHNGHN_01285	5.16e-50	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IIGHNGHN_01286	1.13e-137	azlC	-	-	E	-	-	-	branched-chain amino acid
IIGHNGHN_01287	1.33e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
IIGHNGHN_01288	1.45e-297	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IIGHNGHN_01289	2.3e-222	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IIGHNGHN_01290	7.89e-39	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IIGHNGHN_01291	7.06e-93	-	-	-	-	-	-	-	-
IIGHNGHN_01292	5.48e-114	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IIGHNGHN_01293	5.14e-137	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IIGHNGHN_01294	3.96e-179	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
IIGHNGHN_01295	3.21e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGHNGHN_01296	5.55e-66	-	-	-	S	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
IIGHNGHN_01299	1.03e-114	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
IIGHNGHN_01300	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IIGHNGHN_01301	5.47e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IIGHNGHN_01302	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
IIGHNGHN_01303	0.0	-	-	-	-	-	-	-	-
IIGHNGHN_01304	9.06e-167	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_01305	9.95e-276	-	-	-	G	-	-	-	symporter
IIGHNGHN_01306	5.92e-88	-	-	-	K	-	-	-	sequence-specific DNA binding
IIGHNGHN_01307	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
IIGHNGHN_01309	3.52e-274	melB	-	-	G	-	-	-	symporter
IIGHNGHN_01310	4e-225	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
IIGHNGHN_01311	1.51e-186	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
IIGHNGHN_01312	1.43e-256	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
IIGHNGHN_01313	4.55e-303	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
IIGHNGHN_01314	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IIGHNGHN_01315	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IIGHNGHN_01316	1.5e-91	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01317	3.71e-119	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IIGHNGHN_01318	3.11e-26	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IIGHNGHN_01319	2.2e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_01320	8.07e-108	-	-	-	KTV	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIGHNGHN_01321	2.07e-217	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
IIGHNGHN_01322	1.37e-220	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IIGHNGHN_01323	1.19e-167	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IIGHNGHN_01324	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IIGHNGHN_01327	1.69e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IIGHNGHN_01328	2.19e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIGHNGHN_01329	2.8e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIGHNGHN_01330	9e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF3899)
IIGHNGHN_01331	1.06e-90	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_01332	2.21e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IIGHNGHN_01333	0.0	xpkA	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IIGHNGHN_01334	3.51e-184	yxeH	-	-	S	-	-	-	hydrolase
IIGHNGHN_01335	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IIGHNGHN_01336	1.33e-192	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
IIGHNGHN_01337	7.06e-102	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IIGHNGHN_01338	8.56e-76	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIGHNGHN_01339	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIGHNGHN_01340	2.31e-95	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01341	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IIGHNGHN_01342	3.26e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IIGHNGHN_01343	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGHNGHN_01344	1.86e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGHNGHN_01345	1.21e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIGHNGHN_01346	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IIGHNGHN_01347	1.94e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IIGHNGHN_01351	1.85e-107	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01354	6.25e-46	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IIGHNGHN_01355	3.93e-141	-	-	-	S	-	-	-	Cell surface protein
IIGHNGHN_01356	2.62e-129	XK27_00720	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	regulation of response to stimulus
IIGHNGHN_01357	4.93e-295	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01358	8.05e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIGHNGHN_01359	2.17e-127	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IIGHNGHN_01360	2.1e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IIGHNGHN_01361	7.79e-192	-	-	-	-	-	-	-	-
IIGHNGHN_01362	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIGHNGHN_01363	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIGHNGHN_01364	5.82e-272	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
IIGHNGHN_01365	1.37e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIGHNGHN_01366	1.53e-268	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIGHNGHN_01368	1.45e-80	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IIGHNGHN_01369	7.47e-148	-	-	-	S	-	-	-	(CBS) domain
IIGHNGHN_01371	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IIGHNGHN_01372	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IIGHNGHN_01373	1.72e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIGHNGHN_01374	1.71e-202	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IIGHNGHN_01375	3.7e-262	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IIGHNGHN_01376	2.15e-138	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IIGHNGHN_01377	1.72e-20	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIGHNGHN_01378	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIGHNGHN_01379	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIGHNGHN_01380	3.07e-35	-	-	-	-	-	-	-	-
IIGHNGHN_01381	2.86e-225	-	-	-	S	-	-	-	Pfam Methyltransferase
IIGHNGHN_01382	9.68e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGHNGHN_01383	3.71e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIGHNGHN_01384	9.43e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IIGHNGHN_01385	1.63e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
IIGHNGHN_01386	3.19e-204	degV1	-	-	S	-	-	-	DegV family
IIGHNGHN_01387	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IIGHNGHN_01388	1.39e-255	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IIGHNGHN_01389	9.14e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIGHNGHN_01390	1.29e-191	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
IIGHNGHN_01391	2.5e-278	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_01392	1.39e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01393	5.29e-109	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IIGHNGHN_01394	1.3e-60	-	-	-	-	-	-	-	-
IIGHNGHN_01395	6.95e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIGHNGHN_01396	9.08e-234	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIGHNGHN_01397	0.0	yhaN	-	-	L	-	-	-	AAA domain
IIGHNGHN_01398	8.62e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IIGHNGHN_01399	2.85e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IIGHNGHN_01400	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIGHNGHN_01401	5.9e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIGHNGHN_01402	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IIGHNGHN_01404	3.49e-24	-	-	-	-	-	-	-	-
IIGHNGHN_01405	2.53e-304	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IIGHNGHN_01406	1.19e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IIGHNGHN_01407	4.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
IIGHNGHN_01408	1.05e-119	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IIGHNGHN_01409	2.98e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IIGHNGHN_01410	2.21e-255	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIGHNGHN_01411	1.09e-66	-	-	-	-	-	-	-	-
IIGHNGHN_01412	7.97e-136	-	-	-	S	-	-	-	Iron Transport-associated domain
IIGHNGHN_01413	3.2e-252	-	-	-	M	-	-	-	Iron Transport-associated domain
IIGHNGHN_01414	4.64e-145	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
IIGHNGHN_01415	1.52e-207	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IIGHNGHN_01416	1.42e-220	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIGHNGHN_01417	3.69e-181	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01418	2.36e-218	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGHNGHN_01419	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IIGHNGHN_01420	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGHNGHN_01421	1.51e-195	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
IIGHNGHN_01422	7.44e-114	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IIGHNGHN_01423	4.07e-97	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01424	2.39e-34	-	-	-	-	-	-	-	-
IIGHNGHN_01425	1.08e-102	-	-	-	O	-	-	-	OsmC-like protein
IIGHNGHN_01426	1.87e-32	-	-	-	-	-	-	-	-
IIGHNGHN_01428	8.51e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IIGHNGHN_01429	7.05e-113	-	-	-	-	-	-	-	-
IIGHNGHN_01430	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIGHNGHN_01431	3.96e-60	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
IIGHNGHN_01432	1.19e-89	-	-	-	S	-	-	-	Sigma factor regulator C-terminal
IIGHNGHN_01433	1.27e-256	-	-	-	E	-	-	-	Bacterial extracellular solute-binding proteins, family 5 Middle
IIGHNGHN_01434	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IIGHNGHN_01435	1.12e-15	-	-	-	G	-	-	-	MFS/sugar transport protein
IIGHNGHN_01436	5.25e-233	-	-	-	G	-	-	-	MFS/sugar transport protein
IIGHNGHN_01437	1.11e-151	-	-	-	K	-	-	-	AraC family transcriptional regulator
IIGHNGHN_01438	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Melibiase
IIGHNGHN_01439	1.58e-132	-	-	-	-	-	-	-	-
IIGHNGHN_01440	5.18e-17	-	-	-	-	-	-	-	-
IIGHNGHN_01443	1.15e-189	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IIGHNGHN_01444	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IIGHNGHN_01445	7.61e-269	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
IIGHNGHN_01446	3.04e-198	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IIGHNGHN_01447	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IIGHNGHN_01448	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIGHNGHN_01449	6.05e-103	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
IIGHNGHN_01452	2.84e-215	-	-	-	S	-	-	-	NAD:arginine ADP-ribosyltransferase
IIGHNGHN_01453	1.15e-170	namA	-	-	C	-	-	-	Oxidoreductase
IIGHNGHN_01454	2.14e-53	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
IIGHNGHN_01455	1.6e-72	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_01456	3.37e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IIGHNGHN_01457	3.35e-228	-	-	-	U	-	-	-	FFAT motif binding
IIGHNGHN_01458	6.64e-146	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
IIGHNGHN_01459	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIGHNGHN_01460	4e-203	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
IIGHNGHN_01461	1.3e-90	-	-	-	-	-	-	-	-
IIGHNGHN_01462	6.01e-123	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IIGHNGHN_01463	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IIGHNGHN_01464	3.73e-206	-	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_01465	1.85e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIGHNGHN_01466	0.0	epsA	-	-	I	-	-	-	PAP2 superfamily
IIGHNGHN_01467	2.04e-142	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IIGHNGHN_01468	1.69e-135	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IIGHNGHN_01469	7.01e-244	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IIGHNGHN_01470	5.33e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IIGHNGHN_01471	2.03e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IIGHNGHN_01472	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIGHNGHN_01473	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIGHNGHN_01474	1.02e-119	-	-	-	K	-	-	-	acetyltransferase
IIGHNGHN_01475	3.17e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IIGHNGHN_01476	6.31e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIGHNGHN_01477	1.59e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IIGHNGHN_01478	6.13e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IIGHNGHN_01479	3.28e-197	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIGHNGHN_01480	4.08e-219	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIGHNGHN_01481	7.21e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IIGHNGHN_01482	5.88e-72	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
IIGHNGHN_01483	1.96e-154	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IIGHNGHN_01484	6.12e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIGHNGHN_01485	5.46e-194	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIGHNGHN_01486	3.4e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IIGHNGHN_01487	5.41e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IIGHNGHN_01488	1.25e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IIGHNGHN_01489	4.66e-312	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIGHNGHN_01490	2.49e-166	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IIGHNGHN_01491	2.13e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IIGHNGHN_01492	2.19e-234	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIGHNGHN_01493	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIGHNGHN_01494	3.5e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIGHNGHN_01495	6.35e-157	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IIGHNGHN_01496	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IIGHNGHN_01497	5.39e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IIGHNGHN_01498	6.19e-243	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IIGHNGHN_01499	1.17e-91	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
IIGHNGHN_01500	1.8e-180	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
IIGHNGHN_01501	5.79e-147	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01502	1.87e-248	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIGHNGHN_01503	2.8e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIGHNGHN_01504	8.02e-130	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IIGHNGHN_01505	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_01507	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IIGHNGHN_01508	9.55e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IIGHNGHN_01509	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IIGHNGHN_01510	5.37e-271	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIGHNGHN_01511	7.11e-135	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IIGHNGHN_01512	2.62e-193	-	-	-	S	-	-	-	Zinc-dependent metalloprotease
IIGHNGHN_01513	1.58e-212	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	hydrolase, family 25
IIGHNGHN_01514	3.07e-264	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IIGHNGHN_01515	1.64e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
IIGHNGHN_01516	9.41e-104	yphH	-	-	S	-	-	-	Cupin domain
IIGHNGHN_01517	8.33e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_01518	5.81e-131	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_01520	2.27e-288	-	-	-	-	-	-	-	-
IIGHNGHN_01521	3.07e-203	dkgB	-	-	S	-	-	-	reductase
IIGHNGHN_01522	8.6e-256	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01523	5.66e-259	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01524	9.43e-146	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIGHNGHN_01525	2.29e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
IIGHNGHN_01526	3.29e-73	-	-	-	S	-	-	-	Small secreted protein
IIGHNGHN_01527	2.3e-310	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIGHNGHN_01528	4.31e-257	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IIGHNGHN_01529	1.46e-107	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIGHNGHN_01530	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IIGHNGHN_01531	4.27e-188	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIGHNGHN_01532	1.14e-159	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	pseudouridine synthase activity
IIGHNGHN_01533	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IIGHNGHN_01534	5.98e-66	-	-	-	-	-	-	-	-
IIGHNGHN_01535	1.15e-185	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIGHNGHN_01536	1.29e-158	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
IIGHNGHN_01537	1.13e-70	-	-	-	-	-	-	-	-
IIGHNGHN_01538	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGHNGHN_01539	1.11e-149	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IIGHNGHN_01540	5.38e-131	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IIGHNGHN_01541	6.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
IIGHNGHN_01542	4.54e-116	-	-	-	-	-	-	-	-
IIGHNGHN_01543	3.14e-134	-	-	-	T	-	-	-	EAL domain
IIGHNGHN_01544	3.49e-162	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIGHNGHN_01545	3.6e-92	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIGHNGHN_01546	1.39e-173	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IIGHNGHN_01547	2.98e-120	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IIGHNGHN_01548	5.19e-296	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IIGHNGHN_01550	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IIGHNGHN_01551	2.55e-79	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IIGHNGHN_01552	2.09e-41	-	-	-	-	-	-	-	-
IIGHNGHN_01553	3.78e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIGHNGHN_01554	3.22e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIGHNGHN_01557	4.86e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
IIGHNGHN_01558	8.74e-49	-	-	-	-	-	-	-	-
IIGHNGHN_01559	4.27e-30	-	-	-	-	-	-	-	-
IIGHNGHN_01560	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIGHNGHN_01561	0.0	-	-	-	M	-	-	-	domain protein
IIGHNGHN_01562	6.11e-238	ydbI	-	-	K	-	-	-	AI-2E family transporter
IIGHNGHN_01563	2.53e-269	xylR	-	-	GK	-	-	-	ROK family
IIGHNGHN_01564	3.49e-170	-	-	-	-	-	-	-	-
IIGHNGHN_01565	9.99e-19	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
IIGHNGHN_01566	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IIGHNGHN_01567	2.65e-48	-	-	-	-	-	-	-	-
IIGHNGHN_01568	0.0	-	-	-	U	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IIGHNGHN_01569	1.73e-102	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
IIGHNGHN_01570	1.33e-110	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IIGHNGHN_01571	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IIGHNGHN_01572	3.45e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IIGHNGHN_01573	4.49e-269	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IIGHNGHN_01574	2.76e-246	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
IIGHNGHN_01575	7.95e-222	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IIGHNGHN_01576	1.03e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01577	5.31e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IIGHNGHN_01578	1.36e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IIGHNGHN_01579	1.5e-168	-	-	-	S	-	-	-	B3/4 domain
IIGHNGHN_01580	0.0	-	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
IIGHNGHN_01581	5.19e-31	-	-	-	-	-	-	-	-
IIGHNGHN_01582	2.3e-226	iunH5	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
IIGHNGHN_01583	3.59e-212	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
IIGHNGHN_01584	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IIGHNGHN_01585	7.78e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGHNGHN_01586	1.07e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
IIGHNGHN_01587	2.58e-198	-	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_01588	1.41e-210	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IIGHNGHN_01589	6.27e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
IIGHNGHN_01590	2.02e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IIGHNGHN_01591	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
IIGHNGHN_01592	4.1e-152	-	-	-	S	-	-	-	SNARE associated Golgi protein
IIGHNGHN_01593	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IIGHNGHN_01594	1.16e-287	-	-	-	M	-	-	-	Collagen binding domain
IIGHNGHN_01595	4.75e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IIGHNGHN_01596	2.35e-80	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
IIGHNGHN_01597	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IIGHNGHN_01598	4.63e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01599	1.51e-233	ydhF	-	-	S	-	-	-	Aldo keto reductase
IIGHNGHN_01600	8.76e-264	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator
IIGHNGHN_01601	3.95e-82	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGHNGHN_01602	1.79e-217	-	-	-	-	-	-	-	-
IIGHNGHN_01603	0.0	tagB	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
IIGHNGHN_01604	1.12e-89	-	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01605	2.21e-194	-	-	-	GM	-	-	-	NmrA-like family
IIGHNGHN_01606	7.05e-171	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIGHNGHN_01607	2.2e-160	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IIGHNGHN_01608	3.64e-122	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIGHNGHN_01609	0.0	-	-	-	E	-	-	-	dipeptidase activity
IIGHNGHN_01610	2.56e-176	-	-	-	K	-	-	-	acetyltransferase
IIGHNGHN_01611	3.12e-176	lytE	-	-	M	-	-	-	NlpC/P60 family
IIGHNGHN_01612	3.14e-94	-	-	-	P	-	-	-	ArsC family
IIGHNGHN_01613	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
IIGHNGHN_01614	1.7e-84	-	-	-	K	-	-	-	MarR family
IIGHNGHN_01615	1.1e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIGHNGHN_01616	1.34e-194	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGHNGHN_01617	9.66e-193	galM1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IIGHNGHN_01618	2.39e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIGHNGHN_01619	1.22e-97	-	-	-	-	-	-	-	-
IIGHNGHN_01620	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IIGHNGHN_01621	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIGHNGHN_01622	2.31e-230	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGHNGHN_01623	4e-297	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IIGHNGHN_01624	1.54e-153	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
IIGHNGHN_01625	0.0	-	-	-	S	-	-	-	membrane
IIGHNGHN_01627	2.46e-229	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIGHNGHN_01628	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IIGHNGHN_01629	1.08e-124	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IIGHNGHN_01630	9e-294	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IIGHNGHN_01631	7.15e-179	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
IIGHNGHN_01632	1.2e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
IIGHNGHN_01633	2.53e-182	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIGHNGHN_01634	5.07e-200	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_01635	7.31e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGHNGHN_01636	9.51e-317	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIGHNGHN_01637	4.72e-203	-	-	-	-	-	-	-	-
IIGHNGHN_01638	4.14e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIGHNGHN_01639	2.16e-205	-	-	-	I	-	-	-	Carboxylesterase family
IIGHNGHN_01640	2.67e-189	-	-	-	-	-	-	-	-
IIGHNGHN_01641	6.12e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGHNGHN_01642	2.58e-85	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGHNGHN_01643	1.11e-50	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
IIGHNGHN_01644	6.89e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIGHNGHN_01645	0.0	nox	-	-	C	-	-	-	NADH oxidase
IIGHNGHN_01646	1.29e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IIGHNGHN_01647	1.04e-305	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIGHNGHN_01648	2.18e-165	-	1.1.1.53	-	IQ	ko:K00038	ko00140,ko01100,map00140,map01100	ko00000,ko00001,ko01000	reductase
IIGHNGHN_01649	4.1e-49	-	-	-	-	-	-	-	-
IIGHNGHN_01650	3.84e-103	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IIGHNGHN_01651	3.33e-139	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IIGHNGHN_01652	1.05e-162	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	2-keto-3-deoxygluconate permease
IIGHNGHN_01653	9.89e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIGHNGHN_01654	9.24e-185	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IIGHNGHN_01655	8.46e-08	-	-	-	-	-	-	-	-
IIGHNGHN_01656	9.58e-129	-	-	-	K	-	-	-	Bacterial transcriptional regulator
IIGHNGHN_01657	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IIGHNGHN_01658	4.61e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_01659	1.7e-117	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIGHNGHN_01660	2.19e-290	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IIGHNGHN_01661	2.5e-146	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGHNGHN_01662	8.81e-44	-	-	-	-	-	-	-	-
IIGHNGHN_01663	1.19e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IIGHNGHN_01664	3.69e-285	hpk2	-	-	T	-	-	-	Histidine kinase
IIGHNGHN_01665	3.02e-57	-	-	-	-	-	-	-	-
IIGHNGHN_01666	3.7e-96	-	-	-	-	-	-	-	-
IIGHNGHN_01667	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IIGHNGHN_01668	4.01e-207	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
IIGHNGHN_01669	8.35e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIGHNGHN_01670	2.16e-75	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
IIGHNGHN_01671	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IIGHNGHN_01672	6.91e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_01673	1.17e-272	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IIGHNGHN_01674	1.3e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IIGHNGHN_01675	3.92e-134	-	-	-	-	-	-	-	-
IIGHNGHN_01676	3.51e-308	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
IIGHNGHN_01677	1.84e-236	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
IIGHNGHN_01678	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIGHNGHN_01679	8.04e-165	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IIGHNGHN_01680	2.36e-291	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IIGHNGHN_01681	1.06e-233	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IIGHNGHN_01682	2.53e-283	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IIGHNGHN_01683	1.03e-58	-	-	-	-	-	-	-	-
IIGHNGHN_01684	1.41e-285	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01685	1.39e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01686	1.01e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIGHNGHN_01687	3.23e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIGHNGHN_01688	4.22e-302	-	-	-	-	-	-	-	-
IIGHNGHN_01689	0.0	-	-	-	-	-	-	-	-
IIGHNGHN_01690	5.02e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
IIGHNGHN_01691	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
IIGHNGHN_01692	1.35e-128	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IIGHNGHN_01693	1.24e-314	xylP1	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGHNGHN_01694	8.98e-122	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_01695	2.88e-47	-	-	-	-	-	-	-	-
IIGHNGHN_01696	1.14e-88	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIGHNGHN_01697	2.17e-133	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIGHNGHN_01698	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IIGHNGHN_01699	5.46e-157	-	-	-	-	-	-	-	-
IIGHNGHN_01700	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IIGHNGHN_01701	3.33e-243	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IIGHNGHN_01702	3.33e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IIGHNGHN_01703	1.63e-199	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
IIGHNGHN_01705	2.97e-83	-	-	-	S	-	-	-	Cupredoxin-like domain
IIGHNGHN_01706	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IIGHNGHN_01707	1.16e-203	morA	-	-	S	-	-	-	reductase
IIGHNGHN_01708	1.52e-282	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGHNGHN_01709	2.86e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IIGHNGHN_01710	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IIGHNGHN_01711	4.76e-214	-	-	-	EG	-	-	-	EamA-like transporter family
IIGHNGHN_01712	3.85e-151	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
IIGHNGHN_01713	1.6e-138	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
IIGHNGHN_01714	7.75e-193	-	-	-	-	-	-	-	-
IIGHNGHN_01715	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGHNGHN_01717	5.82e-20	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IIGHNGHN_01718	4.98e-111	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IIGHNGHN_01719	2.33e-29	-	-	-	-	-	-	-	-
IIGHNGHN_01720	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IIGHNGHN_01721	1.12e-109	-	-	-	K	-	-	-	MarR family
IIGHNGHN_01722	5.19e-127	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIGHNGHN_01723	1.56e-257	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IIGHNGHN_01725	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIGHNGHN_01726	5.7e-209	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01727	1.02e-88	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IIGHNGHN_01728	1.85e-239	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGHNGHN_01729	1.86e-286	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGHNGHN_01730	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01731	1.54e-88	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IIGHNGHN_01732	1.17e-143	-	-	-	-	-	-	-	-
IIGHNGHN_01733	1.11e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IIGHNGHN_01734	4.02e-126	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_01735	3.75e-93	-	-	-	C	-	-	-	Flavodoxin
IIGHNGHN_01736	2.71e-280	fabV	1.3.1.44, 1.3.1.9	-	I	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	NAD(P)H binding domain of trans-2-enoyl-CoA reductase
IIGHNGHN_01737	4.19e-238	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIGHNGHN_01738	1.03e-172	-	-	-	S	-	-	-	Putative adhesin
IIGHNGHN_01739	5.17e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
IIGHNGHN_01740	5.12e-71	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IIGHNGHN_01741	3.4e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
IIGHNGHN_01742	1.53e-208	-	-	-	G	-	-	-	Peptidase_C39 like family
IIGHNGHN_01743	4.44e-251	-	-	-	M	-	-	-	NlpC/P60 family
IIGHNGHN_01744	3.65e-19	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
IIGHNGHN_01745	2.26e-148	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIGHNGHN_01746	2.58e-96	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IIGHNGHN_01748	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIGHNGHN_01749	2.11e-146	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
IIGHNGHN_01750	1.68e-50	-	-	-	-	-	-	-	-
IIGHNGHN_01751	1.14e-171	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IIGHNGHN_01752	1.75e-155	-	-	-	S	-	-	-	Membrane
IIGHNGHN_01753	0.0	-	-	-	O	-	-	-	Pro-kumamolisin, activation domain
IIGHNGHN_01754	3.21e-212	-	-	-	I	-	-	-	Alpha beta
IIGHNGHN_01755	2.71e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IIGHNGHN_01756	3.41e-231	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIGHNGHN_01757	4.58e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_01758	1.53e-153	-	-	-	GM	-	-	-	NmrA-like family
IIGHNGHN_01759	7.64e-308	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIGHNGHN_01760	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIGHNGHN_01761	8.14e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIGHNGHN_01762	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIGHNGHN_01763	2.77e-94	usp1	-	-	T	-	-	-	Universal stress protein family
IIGHNGHN_01764	5.49e-156	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
IIGHNGHN_01765	1.94e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
IIGHNGHN_01766	1.06e-48	-	-	-	-	-	-	-	-
IIGHNGHN_01771	5.75e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_01772	2.86e-97	-	-	-	S	ko:K02348	-	ko00000	Gnat family
IIGHNGHN_01773	1.33e-106	padR	-	-	K	-	-	-	Virulence activator alpha C-term
IIGHNGHN_01774	4.33e-132	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IIGHNGHN_01776	3.05e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IIGHNGHN_01778	1.24e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IIGHNGHN_01779	4.36e-98	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
IIGHNGHN_01780	6.67e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IIGHNGHN_01781	8.88e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_01782	1.84e-273	-	-	-	S	-	-	-	ABC-2 family transporter protein
IIGHNGHN_01783	4.4e-157	dctR	-	-	K	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
IIGHNGHN_01784	0.0	yufL	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
IIGHNGHN_01785	3.08e-241	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGHNGHN_01786	1.78e-243	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IIGHNGHN_01787	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IIGHNGHN_01788	2.22e-120	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IIGHNGHN_01789	2.49e-87	-	-	-	-	-	-	-	-
IIGHNGHN_01790	1.56e-218	-	-	-	C	-	-	-	Aldo keto reductase
IIGHNGHN_01791	2.61e-66	-	-	-	-	-	-	-	-
IIGHNGHN_01792	7.18e-158	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion channel
IIGHNGHN_01793	3.4e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGHNGHN_01794	9.2e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IIGHNGHN_01795	2.15e-116	usp5	-	-	T	-	-	-	universal stress protein
IIGHNGHN_01796	0.0	-	-	-	S	-	-	-	membrane
IIGHNGHN_01797	3.33e-85	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IIGHNGHN_01798	1.56e-181	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IIGHNGHN_01799	7.77e-286	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIGHNGHN_01800	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
IIGHNGHN_01801	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IIGHNGHN_01803	8.14e-64	-	-	-	-	-	-	-	-
IIGHNGHN_01804	8.07e-91	-	-	-	-	-	-	-	-
IIGHNGHN_01805	4.97e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIGHNGHN_01806	1.1e-102	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IIGHNGHN_01807	3.76e-244	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIGHNGHN_01808	1.33e-226	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIGHNGHN_01809	1.14e-229	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01810	3.95e-224	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIGHNGHN_01811	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IIGHNGHN_01812	8.17e-60	-	-	-	K	-	-	-	transcriptional regulator
IIGHNGHN_01813	1.16e-214	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01814	4.14e-68	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIGHNGHN_01815	1.4e-99	uspA3	-	-	T	-	-	-	universal stress protein
IIGHNGHN_01816	6.26e-215	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IIGHNGHN_01818	2.76e-164	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
IIGHNGHN_01819	2.55e-266	-	-	-	T	-	-	-	protein histidine kinase activity
IIGHNGHN_01820	7.55e-256	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IIGHNGHN_01821	2.48e-174	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IIGHNGHN_01822	9.05e-93	-	-	-	-	-	-	-	-
IIGHNGHN_01823	1.43e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIGHNGHN_01824	5.76e-141	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
IIGHNGHN_01825	1.75e-169	gntR1	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IIGHNGHN_01826	1.42e-118	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIGHNGHN_01827	1.47e-174	-	-	-	-	-	-	-	-
IIGHNGHN_01828	1.4e-70	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01829	2.17e-27	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IIGHNGHN_01831	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01833	3.23e-288	-	-	-	S	-	-	-	module of peptide synthetase
IIGHNGHN_01834	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IIGHNGHN_01835	0.0	-	5.1.2.7	-	S	ko:K21619	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	tagaturonate epimerase
IIGHNGHN_01836	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGHNGHN_01837	2.14e-233	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
IIGHNGHN_01838	1.72e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IIGHNGHN_01839	3.03e-166	-	-	-	K	-	-	-	FCD domain
IIGHNGHN_01840	1.94e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IIGHNGHN_01841	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IIGHNGHN_01842	8.15e-240	-	-	-	C	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGHNGHN_01843	3.04e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IIGHNGHN_01844	3.21e-211	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
IIGHNGHN_01845	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
IIGHNGHN_01846	0.0	uidA	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
IIGHNGHN_01848	4.74e-109	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
IIGHNGHN_01849	5.72e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IIGHNGHN_01850	1.58e-119	-	-	-	-	-	-	-	-
IIGHNGHN_01851	1.64e-61	-	-	-	-	-	-	-	-
IIGHNGHN_01852	2.76e-138	-	-	-	-	-	-	-	-
IIGHNGHN_01853	3.39e-274	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIGHNGHN_01854	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01855	1.39e-74	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
IIGHNGHN_01856	1.03e-155	dgk2	-	-	F	-	-	-	Deoxynucleoside kinase
IIGHNGHN_01857	1.5e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIGHNGHN_01858	3.02e-152	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IIGHNGHN_01859	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
IIGHNGHN_01860	3.69e-189	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
IIGHNGHN_01861	8.55e-78	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
IIGHNGHN_01862	1.61e-23	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01863	5.13e-125	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
IIGHNGHN_01864	5.36e-203	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
IIGHNGHN_01865	6.48e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIGHNGHN_01866	1.51e-200	-	-	-	S	-	-	-	Nuclease-related domain
IIGHNGHN_01867	1.56e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IIGHNGHN_01868	2.17e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIGHNGHN_01869	6.84e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IIGHNGHN_01870	7.68e-274	pbpX2	-	-	V	-	-	-	Beta-lactamase
IIGHNGHN_01871	2.15e-52	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IIGHNGHN_01872	1.5e-140	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IIGHNGHN_01873	4.41e-251	yueF	-	-	S	-	-	-	AI-2E family transporter
IIGHNGHN_01874	2.51e-98	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
IIGHNGHN_01875	3.8e-195	-	-	-	-	-	-	-	-
IIGHNGHN_01876	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
IIGHNGHN_01877	8.21e-114	-	-	-	-	-	-	-	-
IIGHNGHN_01878	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIGHNGHN_01879	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_01880	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IIGHNGHN_01881	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGHNGHN_01882	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IIGHNGHN_01883	3.08e-262	-	-	-	G	-	-	-	MucBP domain
IIGHNGHN_01884	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IIGHNGHN_01885	2.24e-41	-	-	-	-	-	-	-	-
IIGHNGHN_01886	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IIGHNGHN_01887	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIGHNGHN_01888	5.74e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIGHNGHN_01889	7.33e-248	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIGHNGHN_01890	6.38e-235	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIGHNGHN_01891	3.96e-49	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IIGHNGHN_01892	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIGHNGHN_01893	6.79e-182	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIGHNGHN_01894	8.34e-194	-	-	-	U	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIGHNGHN_01895	8.69e-314	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IIGHNGHN_01896	7.65e-272	msmK2	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIGHNGHN_01897	1.12e-166	-	-	-	F	-	-	-	NUDIX domain
IIGHNGHN_01898	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIGHNGHN_01899	5.49e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
IIGHNGHN_01900	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGHNGHN_01901	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IIGHNGHN_01902	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IIGHNGHN_01903	2.56e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IIGHNGHN_01904	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IIGHNGHN_01905	7.68e-100	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IIGHNGHN_01906	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IIGHNGHN_01907	3.1e-132	-	-	-	K	-	-	-	acetyltransferase
IIGHNGHN_01908	4.81e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IIGHNGHN_01909	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IIGHNGHN_01910	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IIGHNGHN_01911	1.24e-152	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IIGHNGHN_01912	1.14e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIGHNGHN_01913	5.06e-259	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIGHNGHN_01914	1.11e-238	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIGHNGHN_01915	7.11e-203	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIGHNGHN_01916	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_01917	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_01918	2.8e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIGHNGHN_01919	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01920	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01921	4.49e-195	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IIGHNGHN_01922	8.35e-175	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01923	5.36e-219	-	-	-	-	-	-	-	-
IIGHNGHN_01924	4.52e-47	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IIGHNGHN_01925	2.62e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IIGHNGHN_01926	1.3e-97	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IIGHNGHN_01927	8.06e-96	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
IIGHNGHN_01928	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIGHNGHN_01929	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIGHNGHN_01930	9.02e-228	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IIGHNGHN_01932	4.19e-113	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IIGHNGHN_01933	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IIGHNGHN_01934	3.7e-88	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIGHNGHN_01935	8.36e-162	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIGHNGHN_01938	1.09e-153	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IIGHNGHN_01939	3.31e-214	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIGHNGHN_01940	1.35e-213	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_01941	5.72e-207	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IIGHNGHN_01942	1.18e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_01943	2.56e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIGHNGHN_01944	1.14e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01945	4.19e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IIGHNGHN_01946	3.47e-164	-	-	-	P	-	-	-	integral membrane protein, YkoY family
IIGHNGHN_01947	2.9e-310	-	3.4.16.4	-	V	ko:K01286	-	ko00000,ko01000	SH3-like domain
IIGHNGHN_01948	5.07e-143	acmA	-	-	NU	-	-	-	mannosyl-glycoprotein
IIGHNGHN_01949	1.9e-233	-	-	-	S	-	-	-	DUF218 domain
IIGHNGHN_01950	1.92e-240	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIGHNGHN_01951	3.24e-171	-	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IIGHNGHN_01952	3.66e-20	-	-	-	-	-	-	-	-
IIGHNGHN_01953	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IIGHNGHN_01954	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_01955	3.27e-118	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IIGHNGHN_01956	2.4e-107	-	-	-	K	-	-	-	MerR family regulatory protein
IIGHNGHN_01957	2.64e-86	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
IIGHNGHN_01958	2.58e-98	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
IIGHNGHN_01959	1.34e-158	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
IIGHNGHN_01960	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIGHNGHN_01961	4.49e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IIGHNGHN_01962	1.15e-184	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGHNGHN_01963	2.86e-244	-	-	-	S	-	-	-	Protease prsW family
IIGHNGHN_01964	8.68e-229	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
IIGHNGHN_01965	6.95e-10	-	-	-	-	-	-	-	-
IIGHNGHN_01966	1.68e-127	-	-	-	-	-	-	-	-
IIGHNGHN_01967	7.18e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIGHNGHN_01968	3.27e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGHNGHN_01969	1.3e-300	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIGHNGHN_01970	2.63e-39	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IIGHNGHN_01971	1.61e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
IIGHNGHN_01972	2.49e-73	-	-	-	S	-	-	-	LuxR family transcriptional regulator
IIGHNGHN_01973	4.35e-165	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
IIGHNGHN_01974	3.56e-279	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGHNGHN_01975	6.75e-216	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGHNGHN_01976	1.04e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGHNGHN_01977	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IIGHNGHN_01978	4.31e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIGHNGHN_01979	5.69e-154	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IIGHNGHN_01980	4.78e-79	-	-	-	-	-	-	-	-
IIGHNGHN_01981	1.59e-10	-	-	-	-	-	-	-	-
IIGHNGHN_01983	1.45e-54	-	-	-	-	-	-	-	-
IIGHNGHN_01984	5.43e-276	-	-	-	-	-	-	-	-
IIGHNGHN_01985	1.85e-239	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IIGHNGHN_01986	1.6e-34	-	-	-	-	-	-	-	-
IIGHNGHN_01987	1.36e-314	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IIGHNGHN_01988	5.15e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGHNGHN_01989	1.72e-268	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IIGHNGHN_01991	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIGHNGHN_01992	4.13e-196	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IIGHNGHN_01993	1.46e-195	-	-	-	C	-	-	-	Aldo keto reductase
IIGHNGHN_01994	4.07e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
IIGHNGHN_01995	1.32e-89	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
IIGHNGHN_01996	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
IIGHNGHN_01997	2.7e-162	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
IIGHNGHN_01998	3.45e-301	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
IIGHNGHN_01999	4.6e-171	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
IIGHNGHN_02000	4.42e-289	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IIGHNGHN_02001	8.33e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
IIGHNGHN_02002	1.81e-159	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IIGHNGHN_02003	3.38e-226	-	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
IIGHNGHN_02004	8.39e-54	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_02007	4.94e-268	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIGHNGHN_02008	8.33e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_02009	3.45e-173	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGHNGHN_02010	1.63e-259	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGHNGHN_02011	1.69e-189	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIGHNGHN_02012	6.02e-193	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IIGHNGHN_02013	4.2e-215	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IIGHNGHN_02014	3.04e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IIGHNGHN_02015	2.61e-76	-	-	-	-	-	-	-	-
IIGHNGHN_02016	3.19e-41	-	-	-	-	-	-	-	-
IIGHNGHN_02017	5.26e-58	-	-	-	-	-	-	-	-
IIGHNGHN_02018	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
IIGHNGHN_02019	1.82e-161	-	-	-	-	-	-	-	-
IIGHNGHN_02020	2.29e-222	-	-	-	-	-	-	-	-
IIGHNGHN_02021	8.31e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIGHNGHN_02022	1.72e-103	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIGHNGHN_02023	0.0	ybeC	-	-	E	-	-	-	amino acid
IIGHNGHN_02024	1.07e-151	-	-	-	S	-	-	-	membrane
IIGHNGHN_02025	4.21e-146	-	-	-	S	-	-	-	VIT family
IIGHNGHN_02026	2.56e-119	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IIGHNGHN_02027	1.61e-219	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IIGHNGHN_02029	1.15e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IIGHNGHN_02030	1.44e-256	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IIGHNGHN_02032	5.18e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIGHNGHN_02033	1.42e-190	-	-	-	-	-	-	-	-
IIGHNGHN_02034	2.64e-114	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_02035	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IIGHNGHN_02036	3.68e-119	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
IIGHNGHN_02037	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IIGHNGHN_02039	1.52e-238	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIGHNGHN_02040	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IIGHNGHN_02041	5.36e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIGHNGHN_02042	3.31e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIGHNGHN_02043	5.26e-316	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IIGHNGHN_02044	4.9e-49	-	-	-	-	-	-	-	-
IIGHNGHN_02045	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IIGHNGHN_02046	1.27e-248	galM1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IIGHNGHN_02047	1.3e-264	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
IIGHNGHN_02048	3.54e-185	fixA	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein domain
IIGHNGHN_02049	3.23e-221	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
IIGHNGHN_02050	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
IIGHNGHN_02051	9.32e-98	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IIGHNGHN_02052	1.57e-242	-	-	-	G	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IIGHNGHN_02053	1.04e-163	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIGHNGHN_02054	2.39e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IIGHNGHN_02055	1.66e-105	-	-	-	S	-	-	-	ASCH
IIGHNGHN_02056	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_02057	8.06e-33	-	-	-	-	-	-	-	-
IIGHNGHN_02058	3.31e-195	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IIGHNGHN_02059	9.85e-179	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIGHNGHN_02060	1.99e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IIGHNGHN_02061	7.83e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IIGHNGHN_02062	1.01e-91	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IIGHNGHN_02063	8.67e-160	-	-	-	S	-	-	-	HAD-hyrolase-like
IIGHNGHN_02064	2.72e-102	-	-	-	T	-	-	-	Universal stress protein family
IIGHNGHN_02065	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
IIGHNGHN_02066	3.75e-147	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
IIGHNGHN_02067	3.24e-95	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
IIGHNGHN_02068	5.02e-185	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIGHNGHN_02069	8.99e-109	-	-	-	-	-	-	-	-
IIGHNGHN_02070	1.32e-305	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
IIGHNGHN_02071	3.09e-62	-	-	-	-	-	-	-	-
IIGHNGHN_02072	2.06e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIGHNGHN_02073	2.3e-24	-	-	-	-	-	-	-	-
IIGHNGHN_02074	6.83e-157	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IIGHNGHN_02076	6.14e-45	-	-	-	-	-	-	-	-
IIGHNGHN_02078	3.1e-51	-	-	-	S	-	-	-	Cytochrome B5
IIGHNGHN_02079	2.32e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIGHNGHN_02080	4.53e-139	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
IIGHNGHN_02081	2.63e-69	-	-	-	-	-	-	-	-
IIGHNGHN_02082	5.46e-281	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
IIGHNGHN_02083	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IIGHNGHN_02084	0.0	-	-	-	M	-	-	-	domain, Protein
IIGHNGHN_02085	8.6e-69	-	-	-	-	-	-	-	-
IIGHNGHN_02086	1.46e-239	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIGHNGHN_02087	3.2e-83	-	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
IIGHNGHN_02088	2.82e-234	tas	-	-	C	-	-	-	Aldo/keto reductase family
IIGHNGHN_02089	8.65e-43	-	-	-	-	-	-	-	-
IIGHNGHN_02090	2.57e-226	-	-	-	EG	-	-	-	EamA-like transporter family
IIGHNGHN_02093	1.02e-234	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIGHNGHN_02094	3.63e-51	traA	-	-	L	-	-	-	MobA MobL family protein
IIGHNGHN_02095	1.01e-94	-	-	-	G	-	-	-	PFAM glycoside hydrolase family 39
IIGHNGHN_02096	2.8e-22	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIGHNGHN_02097	5.15e-164	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGHNGHN_02105	1.17e-219	-	-	-	-	-	-	-	-
IIGHNGHN_02106	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIGHNGHN_02107	0.0	-	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
IIGHNGHN_02108	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IIGHNGHN_02109	5.55e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02110	1.36e-220	-	-	-	C	-	-	-	nadph quinone reductase
IIGHNGHN_02111	1.13e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02114	1.26e-268	-	-	-	E	-	-	-	Major Facilitator Superfamily
IIGHNGHN_02115	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IIGHNGHN_02116	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIGHNGHN_02117	3.33e-215	-	-	-	-	-	-	-	-
IIGHNGHN_02118	4.82e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1097)
IIGHNGHN_02119	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IIGHNGHN_02120	6.68e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IIGHNGHN_02121	1.27e-74	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
IIGHNGHN_02122	1.71e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
IIGHNGHN_02123	1.44e-29	-	-	-	S	-	-	-	AAA domain
IIGHNGHN_02124	1.51e-54	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
IIGHNGHN_02125	1.12e-48	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IIGHNGHN_02126	1.75e-29	-	-	-	-	-	-	-	-
IIGHNGHN_02127	1.19e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
IIGHNGHN_02128	6.02e-186	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IIGHNGHN_02129	1.01e-292	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
IIGHNGHN_02130	1.57e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02131	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IIGHNGHN_02132	3.28e-105	-	-	-	S	-	-	-	GtrA-like protein
IIGHNGHN_02133	3.66e-98	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IIGHNGHN_02134	5.77e-127	cadD	-	-	P	-	-	-	Cadmium resistance transporter
IIGHNGHN_02136	1.3e-132	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IIGHNGHN_02137	7.12e-226	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IIGHNGHN_02138	3.4e-182	-	-	-	I	ko:K01066	-	ko00000,ko01000	Esterase
IIGHNGHN_02139	1.48e-45	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_02140	5.73e-104	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
IIGHNGHN_02141	3.94e-156	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IIGHNGHN_02142	5.5e-121	-	-	-	S	-	-	-	regulation of response to stimulus
IIGHNGHN_02143	4.23e-181	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IIGHNGHN_02145	0.000304	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
IIGHNGHN_02146	7.15e-141	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIGHNGHN_02147	1.83e-46	-	-	-	-	-	-	-	-
IIGHNGHN_02148	1.56e-210	-	-	-	-	-	-	-	-
IIGHNGHN_02149	3.94e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_02150	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIGHNGHN_02151	0.000246	-	-	-	-	-	-	-	-
IIGHNGHN_02152	3.18e-106	-	-	-	-	-	-	-	-
IIGHNGHN_02155	3.57e-19	-	-	-	-	-	-	-	-
IIGHNGHN_02156	5.2e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIGHNGHN_02157	6.04e-269	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IIGHNGHN_02158	2.33e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IIGHNGHN_02159	3.96e-192	yycI	-	-	S	-	-	-	YycH protein
IIGHNGHN_02160	2.27e-305	yycH	-	-	S	-	-	-	YycH protein
IIGHNGHN_02161	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIGHNGHN_02162	1.19e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IIGHNGHN_02164	1.04e-163	-	-	-	E	-	-	-	Matrixin
IIGHNGHN_02165	1.43e-52	-	-	-	-	-	-	-	-
IIGHNGHN_02166	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_02167	1.68e-37	-	-	-	-	-	-	-	-
IIGHNGHN_02168	1.74e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_02169	3.57e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIGHNGHN_02170	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IIGHNGHN_02172	6.37e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIGHNGHN_02173	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IIGHNGHN_02174	9.76e-94	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIGHNGHN_02175	1.27e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02176	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_02177	1.87e-291	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
IIGHNGHN_02178	4.07e-172	-	-	-	-	-	-	-	-
IIGHNGHN_02179	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IIGHNGHN_02180	2.87e-291	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
IIGHNGHN_02181	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIGHNGHN_02182	5.48e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIGHNGHN_02183	3.89e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IIGHNGHN_02184	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIGHNGHN_02185	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIGHNGHN_02186	1.08e-269	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIGHNGHN_02187	9.18e-49	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IIGHNGHN_02188	9.56e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIGHNGHN_02189	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIGHNGHN_02190	1.61e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IIGHNGHN_02191	9.04e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIGHNGHN_02192	1.67e-185	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIGHNGHN_02193	3.96e-143	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IIGHNGHN_02194	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIGHNGHN_02195	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIGHNGHN_02196	2.58e-80	-	-	-	-	-	-	-	-
IIGHNGHN_02197	4.81e-50	-	-	-	-	-	-	-	-
IIGHNGHN_02198	2.92e-161	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IIGHNGHN_02199	4.53e-50	-	-	-	-	-	-	-	-
IIGHNGHN_02200	8.07e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIGHNGHN_02201	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IIGHNGHN_02202	6.15e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IIGHNGHN_02203	2.51e-120	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IIGHNGHN_02204	4.38e-285	-	-	-	S	-	-	-	module of peptide synthetase
IIGHNGHN_02205	5.2e-276	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	Drug resistance transporter Bcr CflA subfamily
IIGHNGHN_02206	2.55e-137	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIGHNGHN_02207	6.39e-102	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_02208	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IIGHNGHN_02209	3.02e-143	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IIGHNGHN_02210	1.06e-68	-	-	-	-	-	-	-	-
IIGHNGHN_02213	8.3e-117	-	-	-	-	-	-	-	-
IIGHNGHN_02214	5.66e-192	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IIGHNGHN_02215	2.12e-30	-	-	-	-	-	-	-	-
IIGHNGHN_02216	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIGHNGHN_02217	2.37e-197	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
IIGHNGHN_02218	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGHNGHN_02219	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IIGHNGHN_02220	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IIGHNGHN_02224	3.99e-112	ccl	-	-	S	-	-	-	QueT transporter
IIGHNGHN_02225	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIGHNGHN_02226	5.13e-214	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IIGHNGHN_02227	8.07e-118	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IIGHNGHN_02228	2.01e-126	-	-	-	K	-	-	-	LysR substrate binding domain
IIGHNGHN_02229	1.7e-164	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IIGHNGHN_02230	4.3e-205	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_02231	5.9e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IIGHNGHN_02234	4.71e-21	-	-	-	K	-	-	-	toxin-antitoxin pair type II binding
IIGHNGHN_02235	1e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IIGHNGHN_02236	1.5e-229	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IIGHNGHN_02237	4.34e-131	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGHNGHN_02238	3.66e-77	-	-	-	-	-	-	-	-
IIGHNGHN_02239	9.09e-236	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
IIGHNGHN_02240	6.34e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGHNGHN_02241	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IIGHNGHN_02242	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IIGHNGHN_02243	1.65e-213	-	-	-	-	-	-	-	-
IIGHNGHN_02244	5.05e-184	-	-	-	K	-	-	-	Helix-turn-helix domain
IIGHNGHN_02245	7.03e-249	-	-	-	M	-	-	-	domain protein
IIGHNGHN_02246	6.21e-120	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IIGHNGHN_02247	7.07e-92	ywnA	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_02248	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IIGHNGHN_02249	2.51e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
IIGHNGHN_02250	2.65e-171	-	-	-	GM	-	-	-	Male sterility protein
IIGHNGHN_02251	8.93e-45	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02252	4.62e-37	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGHNGHN_02253	1.43e-78	-	-	-	T	-	-	-	EAL domain
IIGHNGHN_02254	4.65e-126	-	-	-	S	-	-	-	Alpha beta hydrolase
IIGHNGHN_02255	3.92e-97	-	-	-	GM	-	-	-	NmrA-like family
IIGHNGHN_02256	5.35e-75	-	-	-	K	ko:K08365	-	ko00000,ko03000	MerR, DNA binding
IIGHNGHN_02257	7.83e-63	-	-	-	C	-	-	-	Flavodoxin
IIGHNGHN_02258	1.85e-224	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGHNGHN_02260	1.19e-175	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
IIGHNGHN_02261	6.57e-50	-	-	-	T	-	-	-	Cyclic nucleotide-binding protein
IIGHNGHN_02262	6.36e-81	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIGHNGHN_02263	5.78e-110	fabG3	1.1.1.53	-	IQ	ko:K00038	ko00140,ko01100,map00140,map01100	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIGHNGHN_02264	9.54e-218	-	-	-	M	-	-	-	MucBP domain
IIGHNGHN_02265	6.24e-55	-	-	-	M	-	-	-	MucBP domain
IIGHNGHN_02266	1.6e-64	-	-	-	-	-	-	-	-
IIGHNGHN_02267	1.07e-38	-	-	-	S	-	-	-	MazG-like family
IIGHNGHN_02268	7.54e-240	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IIGHNGHN_02269	4e-84	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02270	3.26e-255	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
IIGHNGHN_02271	1.03e-201	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
IIGHNGHN_02272	3.02e-145	-	-	-	-	-	-	-	-
IIGHNGHN_02273	1.09e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
IIGHNGHN_02274	2.05e-311	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
IIGHNGHN_02275	9.35e-173	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IIGHNGHN_02276	1.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IIGHNGHN_02277	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
IIGHNGHN_02278	0.0	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IIGHNGHN_02280	2.31e-182	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIGHNGHN_02281	1.09e-224	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGHNGHN_02282	1.63e-314	yhdP	-	-	S	-	-	-	Transporter associated domain
IIGHNGHN_02283	1.62e-80	-	-	-	-	-	-	-	-
IIGHNGHN_02284	3.03e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IIGHNGHN_02285	0.0	-	-	-	E	-	-	-	Amino Acid
IIGHNGHN_02286	1.12e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
IIGHNGHN_02287	6.97e-05	-	-	-	-	-	-	-	-
IIGHNGHN_02288	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IIGHNGHN_02289	8.76e-121	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IIGHNGHN_02290	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IIGHNGHN_02291	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IIGHNGHN_02292	3.39e-111	-	-	-	M	-	-	-	LysM domain protein
IIGHNGHN_02293	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
IIGHNGHN_02294	5.43e-82	-	-	-	M	-	-	-	LysM domain protein
IIGHNGHN_02296	7.5e-76	lysM	-	-	M	-	-	-	LysM domain
IIGHNGHN_02297	5.92e-202	yteR	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IIGHNGHN_02298	4.58e-314	yihO3	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IIGHNGHN_02299	2.57e-119	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
IIGHNGHN_02300	1.61e-190	picA	-	-	G	-	-	-	Glycosyl hydrolases family 28
IIGHNGHN_02302	1.81e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02303	2.87e-213	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IIGHNGHN_02304	4.56e-219	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IIGHNGHN_02305	1.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIGHNGHN_02306	1.41e-75	-	-	-	S	-	-	-	3D domain
IIGHNGHN_02307	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
IIGHNGHN_02308	1.21e-213	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IIGHNGHN_02309	2.92e-152	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIGHNGHN_02310	6.54e-316	-	-	-	V	-	-	-	MatE
IIGHNGHN_02311	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IIGHNGHN_02312	5.82e-257	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGHNGHN_02313	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
IIGHNGHN_02314	2.18e-260	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
IIGHNGHN_02315	4.11e-294	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
IIGHNGHN_02316	4.46e-124	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IIGHNGHN_02318	1.05e-36	-	-	-	T	-	-	-	Universal stress protein family
IIGHNGHN_02319	2.78e-56	-	-	-	-	-	-	-	-
IIGHNGHN_02320	3.43e-59	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IIGHNGHN_02329	7.68e-28	-	-	-	-	-	-	-	-
IIGHNGHN_02331	1.42e-29	-	-	-	S	-	-	-	YopX protein
IIGHNGHN_02334	1.59e-58	-	-	-	S	-	-	-	N-terminal phage replisome organiser (Phage_rep_org_N)
IIGHNGHN_02335	7.82e-111	-	-	-	S	-	-	-	Putative HNHc nuclease
IIGHNGHN_02336	3.51e-68	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIGHNGHN_02337	4.76e-57	-	-	-	S	-	-	-	ERF superfamily
IIGHNGHN_02338	8.22e-23	-	-	-	S	-	-	-	DNA protection
IIGHNGHN_02347	1.28e-97	-	-	-	S	-	-	-	Phage regulatory protein
IIGHNGHN_02351	4.65e-46	-	-	-	K	-	-	-	Peptidase S24-like
IIGHNGHN_02352	2.16e-42	-	-	-	-	-	-	-	-
IIGHNGHN_02354	1.15e-57	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IIGHNGHN_02356	2.77e-64	-	-	-	KLT	-	-	-	serine threonine protein kinase
IIGHNGHN_02359	5.89e-10	-	-	-	T	-	-	-	COG COG2337 Growth inhibitor
IIGHNGHN_02360	2.93e-85	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGHNGHN_02362	5.79e-62	-	-	-	-	-	-	-	-
IIGHNGHN_02363	1.44e-121	-	-	-	V	-	-	-	VanZ like family
IIGHNGHN_02364	2.39e-108	ohrR	-	-	K	-	-	-	Transcriptional regulator
IIGHNGHN_02365	8.69e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIGHNGHN_02366	8.5e-48	-	-	-	-	-	-	-	-
IIGHNGHN_02367	4.43e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGHNGHN_02368	3.15e-98	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
IIGHNGHN_02370	2.45e-68	repA	-	-	S	-	-	-	Replication initiator protein A
IIGHNGHN_02371	1.99e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
IIGHNGHN_02372	3.58e-52	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
IIGHNGHN_02373	4.63e-68	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
IIGHNGHN_02374	0.0	cdr	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IIGHNGHN_02375	3.23e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
IIGHNGHN_02376	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IIGHNGHN_02377	4.16e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IIGHNGHN_02378	9.43e-147	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIGHNGHN_02379	5.17e-176	-	-	-	T	-	-	-	Tyrosine phosphatase family
IIGHNGHN_02380	1.11e-161	-	-	-	-	-	-	-	-
IIGHNGHN_02381	4.79e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IIGHNGHN_02382	2.63e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IIGHNGHN_02383	7.34e-222	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IIGHNGHN_02384	1.39e-111	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IIGHNGHN_02385	4.38e-163	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIGHNGHN_02386	1.32e-269	-	-	-	EGP	ko:K02030,ko:K07552	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
IIGHNGHN_02387	8.33e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIGHNGHN_02388	4.91e-200	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IIGHNGHN_02389	2.9e-138	-	-	-	-	-	-	-	-
IIGHNGHN_02390	1.05e-53	-	-	-	C	-	-	-	nadph quinone reductase
IIGHNGHN_02391	1.62e-170	-	-	-	S	-	-	-	KR domain
IIGHNGHN_02392	1.74e-85	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IIGHNGHN_02393	5.5e-83	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGHNGHN_02394	9.82e-92	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGHNGHN_02395	2.94e-34	-	-	-	-	-	-	-	-
IIGHNGHN_02396	5.83e-118	-	-	-	-	-	-	-	-
IIGHNGHN_02397	2.88e-43	-	-	-	S	-	-	-	Transglycosylase associated protein
IIGHNGHN_02398	8.95e-199	-	-	-	-	-	-	-	-
IIGHNGHN_02399	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IIGHNGHN_02400	4.16e-227	-	-	-	U	-	-	-	Major Facilitator Superfamily
IIGHNGHN_02401	4.24e-122	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IIGHNGHN_02402	3.35e-87	lysM	-	-	M	-	-	-	LysM domain
IIGHNGHN_02403	7.71e-167	XK27_07210	-	-	S	-	-	-	B3 4 domain
IIGHNGHN_02404	1.75e-157	-	-	-	K	ko:K10914,ko:K21828	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	Cyclic nucleotide-monophosphate binding domain
IIGHNGHN_02405	4.23e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
IIGHNGHN_02406	4.44e-275	arcT	-	-	E	-	-	-	Aminotransferase
IIGHNGHN_02407	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IIGHNGHN_02408	2.48e-252	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIGHNGHN_02409	5.7e-301	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
IIGHNGHN_02410	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IIGHNGHN_02411	1.22e-288	ycbA	2.7.13.3	-	T	ko:K07706,ko:K07717	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	histidine kinase DNA gyrase B
IIGHNGHN_02412	8.33e-190	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
IIGHNGHN_02413	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IIGHNGHN_02414	0.0	arcT	-	-	E	-	-	-	Dipeptidase
IIGHNGHN_02416	1.58e-264	-	-	-	-	-	-	-	-
IIGHNGHN_02417	1.52e-136	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IIGHNGHN_02418	4.85e-239	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGHNGHN_02419	2.96e-215	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IIGHNGHN_02420	1.1e-281	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIGHNGHN_02421	1.97e-87	-	-	-	S	-	-	-	PFAM Metallo-beta-lactamase superfamily
IIGHNGHN_02422	1.71e-06	-	-	-	CK	-	-	-	HEAT repeats
IIGHNGHN_02424	6.75e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
IIGHNGHN_02425	1.23e-52	-	-	-	-	-	-	-	-
IIGHNGHN_02426	9.51e-102	yafP	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IIGHNGHN_02427	2.86e-97	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
IIGHNGHN_02429	2.85e-47	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IIGHNGHN_02430	0.0	ydaO	-	-	E	-	-	-	amino acid
IIGHNGHN_02431	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIGHNGHN_02432	1.56e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIGHNGHN_02433	3.29e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIGHNGHN_02434	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IIGHNGHN_02435	8.86e-62	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IIGHNGHN_02436	5.18e-272	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IIGHNGHN_02437	1.74e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIGHNGHN_02438	9.52e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IIGHNGHN_02439	5.58e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IIGHNGHN_02440	3.29e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IIGHNGHN_02441	1.36e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIGHNGHN_02442	4.38e-60	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IIGHNGHN_02443	7.34e-226	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIGHNGHN_02444	1.44e-72	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IIGHNGHN_02445	7.79e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIGHNGHN_02446	2.48e-52	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IIGHNGHN_02447	7.57e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIGHNGHN_02448	6.76e-56	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIGHNGHN_02449	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIGHNGHN_02450	7.06e-120	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIGHNGHN_02451	1.78e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IIGHNGHN_02452	1.92e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IIGHNGHN_02453	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIGHNGHN_02454	1.8e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIGHNGHN_02455	4.21e-213	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IIGHNGHN_02456	1.54e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IIGHNGHN_02457	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIGHNGHN_02458	7.9e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIGHNGHN_02459	1.3e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIGHNGHN_02460	1.75e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIGHNGHN_02461	4.14e-94	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIGHNGHN_02462	1.61e-127	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IIGHNGHN_02463	1.27e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIGHNGHN_02464	7.92e-129	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
IIGHNGHN_02465	1.04e-116	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
IIGHNGHN_02466	2.12e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIGHNGHN_02467	7.28e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIGHNGHN_02468	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGHNGHN_02469	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIGHNGHN_02470	4.97e-271	yacL	-	-	S	-	-	-	domain protein
IIGHNGHN_02471	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIGHNGHN_02472	6.13e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IIGHNGHN_02473	4.07e-74	-	-	-	-	-	-	-	-
IIGHNGHN_02474	1.63e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIGHNGHN_02476	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IIGHNGHN_02477	1.68e-293	-	-	-	V	-	-	-	Beta-lactamase
IIGHNGHN_02478	5.67e-157	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIGHNGHN_02479	3.49e-227	-	-	-	EG	-	-	-	EamA-like transporter family
IIGHNGHN_02480	8.11e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IIGHNGHN_02481	3.4e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGHNGHN_02482	3.46e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IIGHNGHN_02483	4.23e-301	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
IIGHNGHN_02484	2.02e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGHNGHN_02485	3.3e-152	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IIGHNGHN_02486	1.51e-35	-	-	-	T	-	-	-	diguanylate cyclase
IIGHNGHN_02487	7.94e-191	-	-	-	T	-	-	-	diguanylate cyclase
IIGHNGHN_02488	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
IIGHNGHN_02489	1.29e-197	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IIGHNGHN_02490	1.13e-175	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IIGHNGHN_02491	1.72e-78	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IIGHNGHN_02492	7.57e-71	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IIGHNGHN_02493	2.83e-138	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IIGHNGHN_02494	3.56e-313	dinF	-	-	V	-	-	-	MatE
IIGHNGHN_02495	1.43e-96	-	-	-	K	-	-	-	MarR family
IIGHNGHN_02496	2.07e-127	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIGHNGHN_02497	1.5e-145	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
IIGHNGHN_02498	8.65e-82	-	-	-	K	-	-	-	transcriptional regulator
IIGHNGHN_02499	5.17e-158	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IIGHNGHN_02500	6.87e-192	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
IIGHNGHN_02502	3.42e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIGHNGHN_02503	1.75e-115	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IIGHNGHN_02504	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IIGHNGHN_02505	8.95e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
IIGHNGHN_02506	9.45e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIGHNGHN_02507	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIGHNGHN_02508	3.69e-178	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IIGHNGHN_02509	1.86e-119	yfbM	-	-	K	-	-	-	FR47-like protein
IIGHNGHN_02510	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IIGHNGHN_02511	2.69e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIGHNGHN_02512	4.03e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIGHNGHN_02515	1.52e-192	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIGHNGHN_02516	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IIGHNGHN_02517	3.2e-70	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IIGHNGHN_02521	6.23e-104	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IIGHNGHN_02522	5.24e-169	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IIGHNGHN_02523	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IIGHNGHN_02524	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IIGHNGHN_02525	8.91e-154	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IIGHNGHN_02526	0.0	-	-	-	E	-	-	-	Peptidase family C69
IIGHNGHN_02527	1.18e-50	-	-	-	-	-	-	-	-
IIGHNGHN_02528	0.0	-	-	-	-	-	-	-	-
IIGHNGHN_02531	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ABC transporter
IIGHNGHN_02533	1.33e-110	-	-	-	M	-	-	-	hydrolase, family 25
IIGHNGHN_02534	3.3e-52	-	-	-	-	-	-	-	-
IIGHNGHN_02537	2.8e-65	-	-	-	-	-	-	-	-
IIGHNGHN_02540	0.0	-	-	-	S	-	-	-	Phage minor structural protein
IIGHNGHN_02541	6.35e-188	-	-	-	S	-	-	-	Phage tail protein
IIGHNGHN_02542	5.33e-226	-	-	-	S	-	-	-	peptidoglycan catabolic process
IIGHNGHN_02543	4.33e-09	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
IIGHNGHN_02544	4.63e-23	-	-	-	S	-	-	-	Phage tail tube protein
IIGHNGHN_02547	1.54e-44	-	-	-	S	-	-	-	Phage head-tail joining protein
IIGHNGHN_02548	0.000127	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IIGHNGHN_02549	2.11e-126	-	-	-	S	-	-	-	Phage capsid family
IIGHNGHN_02550	5.45e-105	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IIGHNGHN_02551	5.15e-140	-	-	-	S	-	-	-	Portal protein
IIGHNGHN_02552	0.0	-	-	-	S	-	-	-	Phage Terminase
IIGHNGHN_02554	3.85e-21	-	-	-	V	-	-	-	HNH endonuclease
IIGHNGHN_02557	4.5e-62	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
IIGHNGHN_02559	1.45e-18	-	-	-	-	-	-	-	-