Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IFMFHLEA_00001	9.9e-240	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IFMFHLEA_00002	5.73e-202	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
IFMFHLEA_00003	2.68e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
IFMFHLEA_00004	2.22e-09	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
IFMFHLEA_00005	1.71e-226	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
IFMFHLEA_00006	1.86e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFMFHLEA_00007	8.07e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IFMFHLEA_00010	2.37e-210	-	-	-	-	-	-	-	-
IFMFHLEA_00011	5.77e-214	-	-	-	-	-	-	-	-
IFMFHLEA_00012	7.72e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00013	7.05e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IFMFHLEA_00014	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IFMFHLEA_00015	1.71e-301	ynbB	-	-	P	-	-	-	aluminum resistance
IFMFHLEA_00016	8.27e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IFMFHLEA_00017	1.48e-90	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IFMFHLEA_00018	4.01e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IFMFHLEA_00019	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IFMFHLEA_00020	3.23e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IFMFHLEA_00021	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IFMFHLEA_00022	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IFMFHLEA_00023	0.0	-	-	-	S	-	-	-	membrane
IFMFHLEA_00024	2.46e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
IFMFHLEA_00025	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMFHLEA_00026	1.06e-69	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IFMFHLEA_00027	3.51e-17	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IFMFHLEA_00028	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IFMFHLEA_00029	1.6e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
IFMFHLEA_00030	3.63e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFMFHLEA_00031	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFMFHLEA_00032	2.59e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IFMFHLEA_00033	1.24e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IFMFHLEA_00034	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFMFHLEA_00035	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IFMFHLEA_00036	1.89e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFMFHLEA_00037	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMFHLEA_00038	6.08e-164	csrR	-	-	K	-	-	-	response regulator
IFMFHLEA_00039	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IFMFHLEA_00040	9.35e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IFMFHLEA_00041	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IFMFHLEA_00042	4.06e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IFMFHLEA_00043	8.11e-159	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IFMFHLEA_00044	4.26e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IFMFHLEA_00045	1.66e-120	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IFMFHLEA_00046	4.78e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IFMFHLEA_00047	8.82e-241	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IFMFHLEA_00048	4.31e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IFMFHLEA_00049	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IFMFHLEA_00050	9.48e-95	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IFMFHLEA_00051	1.92e-118	-	-	-	-	-	-	-	-
IFMFHLEA_00052	1.39e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IFMFHLEA_00053	1.11e-80	-	-	-	K	-	-	-	LytTr DNA-binding domain
IFMFHLEA_00054	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IFMFHLEA_00055	5.35e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IFMFHLEA_00056	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IFMFHLEA_00057	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IFMFHLEA_00058	5.52e-139	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IFMFHLEA_00059	6.72e-205	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IFMFHLEA_00060	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IFMFHLEA_00061	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IFMFHLEA_00062	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IFMFHLEA_00063	3.61e-144	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IFMFHLEA_00064	3.52e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IFMFHLEA_00065	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IFMFHLEA_00066	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMFHLEA_00067	1.15e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMFHLEA_00068	1.88e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMFHLEA_00069	1.24e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IFMFHLEA_00070	1.14e-88	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IFMFHLEA_00071	1.14e-158	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IFMFHLEA_00072	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IFMFHLEA_00073	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IFMFHLEA_00074	1.9e-160	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00075	5.58e-192	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IFMFHLEA_00076	2.68e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IFMFHLEA_00077	2.76e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
IFMFHLEA_00078	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
IFMFHLEA_00079	2.45e-227	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_00080	1.36e-241	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IFMFHLEA_00081	1.67e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IFMFHLEA_00082	1.18e-225	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IFMFHLEA_00083	2.86e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
IFMFHLEA_00084	7.93e-206	-	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_00085	3.62e-89	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IFMFHLEA_00086	2.27e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IFMFHLEA_00087	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IFMFHLEA_00088	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IFMFHLEA_00089	1.47e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFMFHLEA_00090	1.63e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IFMFHLEA_00091	8.15e-94	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
IFMFHLEA_00092	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IFMFHLEA_00093	0.0	-	-	-	S	-	-	-	TerB-C domain
IFMFHLEA_00094	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
IFMFHLEA_00095	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IFMFHLEA_00096	4.47e-81	-	-	-	-	-	-	-	-
IFMFHLEA_00097	1.14e-294	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IFMFHLEA_00098	8.42e-187	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IFMFHLEA_00100	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
IFMFHLEA_00101	0.0	-	-	-	S	-	-	-	AAA ATPase domain
IFMFHLEA_00102	4.51e-59	-	-	-	S	-	-	-	AAA ATPase domain
IFMFHLEA_00103	7.49e-136	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
IFMFHLEA_00104	1.71e-33	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
IFMFHLEA_00105	8.37e-161	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
IFMFHLEA_00107	8.66e-76	-	-	-	-	-	-	-	-
IFMFHLEA_00108	2.66e-270	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IFMFHLEA_00110	3.69e-244	-	-	-	EP	-	-	-	Plasmid replication protein
IFMFHLEA_00111	6.89e-06	-	-	-	-	-	-	-	-
IFMFHLEA_00112	1.14e-295	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMFHLEA_00113	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IFMFHLEA_00114	3.99e-45	-	-	-	-	-	-	-	-
IFMFHLEA_00115	3.99e-88	-	-	-	-	-	-	-	-
IFMFHLEA_00116	1.48e-219	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
IFMFHLEA_00117	2.6e-19	-	-	-	-	-	-	-	-
IFMFHLEA_00118	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_00119	4.35e-207	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IFMFHLEA_00120	2.62e-111	-	-	-	M	-	-	-	LysM domain protein
IFMFHLEA_00121	3.81e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
IFMFHLEA_00122	1e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IFMFHLEA_00123	2.57e-139	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
IFMFHLEA_00124	9.82e-156	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
IFMFHLEA_00125	9.11e-69	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IFMFHLEA_00126	7.11e-236	lacI	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IFMFHLEA_00127	0.0	-	-	-	G	ko:K02027,ko:K10120	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMFHLEA_00128	1.78e-209	-	-	-	P	ko:K10121	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
IFMFHLEA_00129	2.93e-199	msmG	-	-	G	ko:K02026,ko:K10122	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_00130	4.18e-292	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
IFMFHLEA_00131	8.89e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_00132	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
IFMFHLEA_00133	3.18e-92	-	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00135	3.91e-226	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IFMFHLEA_00136	0.0	slpX	-	-	S	-	-	-	SLAP domain
IFMFHLEA_00139	5.81e-272	-	-	-	-	-	-	-	-
IFMFHLEA_00140	2.55e-157	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IFMFHLEA_00141	2.13e-92	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
IFMFHLEA_00142	1.39e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IFMFHLEA_00143	1.85e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
IFMFHLEA_00144	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IFMFHLEA_00145	5.7e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IFMFHLEA_00146	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IFMFHLEA_00147	3.89e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IFMFHLEA_00148	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IFMFHLEA_00149	8.44e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IFMFHLEA_00150	6.32e-83	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IFMFHLEA_00152	1.02e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IFMFHLEA_00153	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IFMFHLEA_00154	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IFMFHLEA_00155	7.29e-267	camS	-	-	S	-	-	-	sex pheromone
IFMFHLEA_00156	4.46e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFMFHLEA_00157	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IFMFHLEA_00158	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFMFHLEA_00159	2.37e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IFMFHLEA_00160	8.38e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IFMFHLEA_00161	4.94e-75	-	-	-	-	-	-	-	-
IFMFHLEA_00162	1.28e-310	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IFMFHLEA_00163	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFMFHLEA_00164	4.2e-30	-	-	-	-	-	-	-	-
IFMFHLEA_00165	1.48e-82	-	-	-	-	-	-	-	-
IFMFHLEA_00166	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
IFMFHLEA_00167	5.51e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
IFMFHLEA_00168	1.05e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IFMFHLEA_00169	9.1e-148	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IFMFHLEA_00170	6.03e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IFMFHLEA_00171	3.15e-62	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
IFMFHLEA_00172	2.43e-76	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
IFMFHLEA_00173	2.98e-246	-	-	-	L	ko:K06400	-	ko00000	Recombinase
IFMFHLEA_00174	3.28e-122	-	-	-	L	-	-	-	Resolvase, N terminal domain
IFMFHLEA_00175	9.05e-231	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
IFMFHLEA_00176	3.49e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMFHLEA_00181	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00182	1.88e-174	-	-	-	S	-	-	-	CAAX protease self-immunity
IFMFHLEA_00183	1.25e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMFHLEA_00184	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IFMFHLEA_00185	3.79e-101	-	-	-	K	-	-	-	acetyltransferase
IFMFHLEA_00186	1.36e-205	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IFMFHLEA_00187	5.13e-141	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_00188	5.81e-165	XK27_08575	-	-	V	ko:K06148	-	ko00000,ko02000	cysteine transport
IFMFHLEA_00189	5.36e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IFMFHLEA_00190	1.39e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFMFHLEA_00191	3.27e-110	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IFMFHLEA_00192	2.03e-67	-	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
IFMFHLEA_00193	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00194	3.81e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IFMFHLEA_00195	1.11e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IFMFHLEA_00196	7.56e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IFMFHLEA_00197	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IFMFHLEA_00198	1.4e-188	-	-	-	-	-	-	-	-
IFMFHLEA_00199	2.22e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_00200	6.57e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IFMFHLEA_00201	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00202	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
IFMFHLEA_00203	8.88e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IFMFHLEA_00204	1.92e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
IFMFHLEA_00205	2.39e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00206	4.3e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_00207	1.43e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00208	8.28e-143	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00209	3.66e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IFMFHLEA_00210	2.75e-95	-	-	-	-	-	-	-	-
IFMFHLEA_00211	5.02e-313	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMFHLEA_00212	5.34e-211	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
IFMFHLEA_00213	9.2e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IFMFHLEA_00214	1.56e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IFMFHLEA_00215	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IFMFHLEA_00216	3.51e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IFMFHLEA_00217	1.98e-175	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IFMFHLEA_00218	1.81e-28	-	-	-	-	-	-	-	-
IFMFHLEA_00219	5.7e-146	-	-	-	-	-	-	-	-
IFMFHLEA_00220	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IFMFHLEA_00221	2.07e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IFMFHLEA_00222	1.21e-93	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IFMFHLEA_00223	3.85e-143	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IFMFHLEA_00224	8.25e-221	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IFMFHLEA_00225	7.73e-79	-	-	-	S	-	-	-	Enterocin A Immunity
IFMFHLEA_00226	3.4e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IFMFHLEA_00227	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IFMFHLEA_00228	2.25e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
IFMFHLEA_00229	7.37e-293	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IFMFHLEA_00230	8.04e-187	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IFMFHLEA_00231	5.93e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMFHLEA_00232	1.35e-196	-	-	-	S	-	-	-	hydrolase
IFMFHLEA_00233	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IFMFHLEA_00234	3.69e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IFMFHLEA_00235	2.25e-105	-	-	-	-	-	-	-	-
IFMFHLEA_00236	5.61e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IFMFHLEA_00237	1.51e-53	-	-	-	-	-	-	-	-
IFMFHLEA_00238	4.33e-154	-	-	-	C	-	-	-	nitroreductase
IFMFHLEA_00239	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IFMFHLEA_00240	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IFMFHLEA_00241	3.27e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
IFMFHLEA_00242	9.79e-168	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IFMFHLEA_00243	2.35e-269	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IFMFHLEA_00244	6.86e-311	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_00247	6.25e-304	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IFMFHLEA_00248	2.45e-214	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
IFMFHLEA_00249	1.09e-135	-	-	-	S	-	-	-	Membrane
IFMFHLEA_00250	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_00251	0.0	-	-	-	G	ko:K02755,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_00252	2.24e-41	-	2.7.1.208, 2.7.1.211	-	G	ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IFMFHLEA_00253	2.69e-191	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IFMFHLEA_00254	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_00255	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IFMFHLEA_00256	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFMFHLEA_00257	5.52e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
IFMFHLEA_00258	9.15e-165	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IFMFHLEA_00259	3.37e-273	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IFMFHLEA_00260	3.15e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00261	1.38e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IFMFHLEA_00262	3.51e-74	-	-	-	-	-	-	-	-
IFMFHLEA_00263	3.26e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IFMFHLEA_00264	3.19e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IFMFHLEA_00265	0.0	yhaN	-	-	L	-	-	-	AAA domain
IFMFHLEA_00266	8.31e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IFMFHLEA_00267	6.93e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IFMFHLEA_00268	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IFMFHLEA_00269	3.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IFMFHLEA_00270	1.34e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IFMFHLEA_00271	2.79e-154	-	-	-	-	-	-	-	-
IFMFHLEA_00272	2.45e-246	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
IFMFHLEA_00273	8.56e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IFMFHLEA_00274	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IFMFHLEA_00275	1.06e-164	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IFMFHLEA_00276	1.29e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IFMFHLEA_00277	3.95e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IFMFHLEA_00279	1.19e-71	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IFMFHLEA_00280	4.1e-251	flp	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_00281	3.16e-72	-	-	-	-	-	-	-	-
IFMFHLEA_00282	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
IFMFHLEA_00283	4.95e-53	-	-	-	S	-	-	-	Enterocin A Immunity
IFMFHLEA_00284	0.0	-	-	-	S	-	-	-	domain, Protein
IFMFHLEA_00285	7.05e-89	-	-	-	S	-	-	-	domain, Protein
IFMFHLEA_00286	6.41e-105	-	-	-	S	-	-	-	Cupin domain
IFMFHLEA_00287	6.36e-193	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IFMFHLEA_00288	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IFMFHLEA_00289	1.39e-22	-	-	-	K	-	-	-	transcriptional regulator
IFMFHLEA_00290	3.3e-94	-	-	-	K	-	-	-	transcriptional regulator
IFMFHLEA_00292	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IFMFHLEA_00293	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IFMFHLEA_00294	7.75e-153	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IFMFHLEA_00295	7.6e-118	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IFMFHLEA_00296	1.29e-150	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IFMFHLEA_00297	1.37e-36	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IFMFHLEA_00298	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00299	5.35e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IFMFHLEA_00304	2.83e-62	-	-	-	-	-	-	-	-
IFMFHLEA_00305	1.3e-99	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IFMFHLEA_00306	1.51e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFMFHLEA_00307	1.97e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMFHLEA_00308	2.93e-173	-	-	-	-	-	-	-	-
IFMFHLEA_00309	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00310	7.42e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00311	1.96e-293	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
IFMFHLEA_00312	7.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IFMFHLEA_00313	1.49e-136	-	-	-	-	-	-	-	-
IFMFHLEA_00314	1.62e-256	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IFMFHLEA_00315	1.71e-170	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IFMFHLEA_00316	7.56e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IFMFHLEA_00317	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IFMFHLEA_00318	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IFMFHLEA_00319	2.9e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
IFMFHLEA_00320	1.74e-112	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFMFHLEA_00321	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IFMFHLEA_00322	5.61e-113	usp5	-	-	T	-	-	-	universal stress protein
IFMFHLEA_00323	7.56e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
IFMFHLEA_00324	4.46e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IFMFHLEA_00325	2.84e-171	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_00326	6.38e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_00327	7.66e-141	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IFMFHLEA_00328	3.65e-109	-	-	-	-	-	-	-	-
IFMFHLEA_00329	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IFMFHLEA_00330	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IFMFHLEA_00331	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IFMFHLEA_00332	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IFMFHLEA_00333	1.29e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IFMFHLEA_00334	1.6e-127	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IFMFHLEA_00335	4.3e-297	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IFMFHLEA_00336	1.88e-292	yttB	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00337	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IFMFHLEA_00338	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IFMFHLEA_00339	6.3e-91	-	-	-	-	-	-	-	-
IFMFHLEA_00340	2.15e-21	-	-	-	-	-	-	-	-
IFMFHLEA_00341	0.0	-	-	-	G	-	-	-	isomerase
IFMFHLEA_00342	1.11e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IFMFHLEA_00343	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IFMFHLEA_00344	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMFHLEA_00345	2.7e-10	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMFHLEA_00346	8.27e-190	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMFHLEA_00347	1.05e-225	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IFMFHLEA_00348	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
IFMFHLEA_00349	5.47e-199	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IFMFHLEA_00350	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_00351	4.63e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IFMFHLEA_00352	9.97e-103	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
IFMFHLEA_00353	4.97e-81	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
IFMFHLEA_00354	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
IFMFHLEA_00355	1.41e-139	-	-	-	-	-	-	-	-
IFMFHLEA_00360	1.98e-96	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IFMFHLEA_00361	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IFMFHLEA_00362	3.83e-61	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IFMFHLEA_00366	3.89e-77	-	-	-	G	-	-	-	polysaccharide catabolic process
IFMFHLEA_00367	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain
IFMFHLEA_00368	2.88e-223	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IFMFHLEA_00369	1.05e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IFMFHLEA_00370	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
IFMFHLEA_00371	1.79e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IFMFHLEA_00372	8.15e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
IFMFHLEA_00373	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IFMFHLEA_00374	1.46e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IFMFHLEA_00386	1.99e-99	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IFMFHLEA_00387	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IFMFHLEA_00388	5.29e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IFMFHLEA_00389	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IFMFHLEA_00390	5.18e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IFMFHLEA_00391	1.5e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IFMFHLEA_00392	2.24e-284	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
IFMFHLEA_00400	4.67e-116	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
IFMFHLEA_00401	8.53e-104	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IFMFHLEA_00402	7.02e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IFMFHLEA_00403	1.14e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IFMFHLEA_00404	6.78e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IFMFHLEA_00405	3.81e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IFMFHLEA_00406	1.39e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IFMFHLEA_00407	3.82e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IFMFHLEA_00408	2.95e-61	-	-	-	-	-	-	-	-
IFMFHLEA_00409	2.13e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IFMFHLEA_00410	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFMFHLEA_00411	4.13e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IFMFHLEA_00412	7.42e-112	-	-	-	-	-	-	-	-
IFMFHLEA_00413	1.02e-93	-	-	-	-	-	-	-	-
IFMFHLEA_00414	1.25e-62	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IFMFHLEA_00415	1.48e-127	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IFMFHLEA_00416	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IFMFHLEA_00417	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IFMFHLEA_00418	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IFMFHLEA_00419	9.05e-55	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IFMFHLEA_00420	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IFMFHLEA_00421	1.08e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IFMFHLEA_00422	2.91e-175	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IFMFHLEA_00423	4.24e-208	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IFMFHLEA_00424	7.54e-149	yjbH	-	-	Q	-	-	-	Thioredoxin
IFMFHLEA_00425	1.46e-145	-	-	-	S	-	-	-	CYTH
IFMFHLEA_00426	1.15e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IFMFHLEA_00427	5.49e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IFMFHLEA_00428	1.81e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IFMFHLEA_00429	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IFMFHLEA_00430	8.93e-153	-	-	-	S	-	-	-	SNARE associated Golgi protein
IFMFHLEA_00431	1.06e-257	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IFMFHLEA_00432	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IFMFHLEA_00433	8.1e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IFMFHLEA_00434	8.9e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IFMFHLEA_00435	1.75e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IFMFHLEA_00436	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IFMFHLEA_00437	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IFMFHLEA_00438	4.09e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IFMFHLEA_00439	2.26e-306	ymfH	-	-	S	-	-	-	Peptidase M16
IFMFHLEA_00440	8.02e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IFMFHLEA_00441	1.43e-160	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IFMFHLEA_00442	1.73e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IFMFHLEA_00443	6.24e-247	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IFMFHLEA_00444	2.13e-292	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IFMFHLEA_00445	3.37e-271	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IFMFHLEA_00446	2.05e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IFMFHLEA_00447	4.82e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IFMFHLEA_00448	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IFMFHLEA_00449	1.75e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IFMFHLEA_00450	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IFMFHLEA_00451	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IFMFHLEA_00452	1.88e-21	-	-	-	-	-	-	-	-
IFMFHLEA_00453	6.85e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IFMFHLEA_00454	4.36e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IFMFHLEA_00455	1.71e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IFMFHLEA_00456	9.38e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IFMFHLEA_00457	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IFMFHLEA_00458	4.02e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IFMFHLEA_00459	5.82e-272	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IFMFHLEA_00460	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IFMFHLEA_00461	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IFMFHLEA_00462	5.93e-60	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IFMFHLEA_00463	1.41e-316	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IFMFHLEA_00464	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IFMFHLEA_00465	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IFMFHLEA_00466	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IFMFHLEA_00467	3.8e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IFMFHLEA_00468	2.44e-116	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IFMFHLEA_00469	5.03e-81	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IFMFHLEA_00470	3.24e-250	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IFMFHLEA_00471	1.17e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IFMFHLEA_00472	2.16e-129	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IFMFHLEA_00473	0.0	-	-	-	S	-	-	-	SH3-like domain
IFMFHLEA_00474	0.0	ycaM	-	-	E	-	-	-	amino acid
IFMFHLEA_00476	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IFMFHLEA_00477	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IFMFHLEA_00478	9.96e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IFMFHLEA_00479	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IFMFHLEA_00480	1.07e-125	-	-	-	-	-	-	-	-
IFMFHLEA_00481	1.02e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IFMFHLEA_00482	1.15e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IFMFHLEA_00483	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IFMFHLEA_00484	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IFMFHLEA_00485	5.26e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IFMFHLEA_00486	7.27e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IFMFHLEA_00487	2.94e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IFMFHLEA_00488	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00489	2.65e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00490	9.5e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_00491	1.06e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IFMFHLEA_00492	3.38e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
IFMFHLEA_00493	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IFMFHLEA_00494	4.85e-191	-	-	-	S	-	-	-	hydrolase
IFMFHLEA_00495	1.45e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IFMFHLEA_00496	7.3e-156	-	-	-	-	-	-	-	-
IFMFHLEA_00497	3.07e-97	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IFMFHLEA_00498	1.37e-269	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IFMFHLEA_00499	4.66e-196	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IFMFHLEA_00500	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_00501	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_00502	6.14e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IFMFHLEA_00503	0.0	-	-	-	E	-	-	-	Amino acid permease
IFMFHLEA_00505	1.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFMFHLEA_00506	2.34e-119	-	-	-	S	-	-	-	VanZ like family
IFMFHLEA_00507	1.97e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IFMFHLEA_00508	7.38e-29	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IFMFHLEA_00509	9.02e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IFMFHLEA_00510	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IFMFHLEA_00511	1.55e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IFMFHLEA_00512	9e-94	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
IFMFHLEA_00513	1.33e-25	-	-	-	-	-	-	-	-
IFMFHLEA_00514	2.61e-120	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IFMFHLEA_00515	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IFMFHLEA_00516	1.35e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFMFHLEA_00518	1.05e-170	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IFMFHLEA_00519	3.52e-224	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IFMFHLEA_00520	4.53e-41	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IFMFHLEA_00521	1.86e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IFMFHLEA_00522	1.68e-81	-	-	-	S	-	-	-	SdpI/YhfL protein family
IFMFHLEA_00523	1.84e-123	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IFMFHLEA_00524	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IFMFHLEA_00525	4.37e-81	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
IFMFHLEA_00526	1.53e-159	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
IFMFHLEA_00527	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IFMFHLEA_00528	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
IFMFHLEA_00529	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IFMFHLEA_00530	5.4e-316	-	-	-	EGP	-	-	-	Major Facilitator
IFMFHLEA_00531	7.36e-251	ampC	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_00534	2.17e-85	-	-	-	-	-	-	-	-
IFMFHLEA_00535	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
IFMFHLEA_00536	1.18e-47	-	-	-	-	-	-	-	-
IFMFHLEA_00537	6.8e-46	-	-	-	-	-	-	-	-
IFMFHLEA_00538	3.84e-90	-	-	-	-	-	-	-	-
IFMFHLEA_00539	2.58e-49	-	-	-	-	-	-	-	-
IFMFHLEA_00541	3.5e-75	-	-	-	K	-	-	-	Transcriptional
IFMFHLEA_00542	1.58e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMFHLEA_00543	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IFMFHLEA_00544	4.64e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IFMFHLEA_00545	1.01e-235	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IFMFHLEA_00546	2.52e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IFMFHLEA_00547	4.93e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IFMFHLEA_00548	1.84e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IFMFHLEA_00549	4.13e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IFMFHLEA_00550	4.36e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFMFHLEA_00551	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IFMFHLEA_00552	6.82e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFMFHLEA_00553	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IFMFHLEA_00554	1.22e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IFMFHLEA_00555	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IFMFHLEA_00556	7.03e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IFMFHLEA_00557	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IFMFHLEA_00558	2.04e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IFMFHLEA_00559	7.58e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IFMFHLEA_00560	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IFMFHLEA_00561	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IFMFHLEA_00562	6.39e-102	uspA	-	-	T	-	-	-	universal stress protein
IFMFHLEA_00563	1.41e-49	-	-	-	-	-	-	-	-
IFMFHLEA_00564	1.18e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IFMFHLEA_00565	9.44e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IFMFHLEA_00566	1.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IFMFHLEA_00567	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IFMFHLEA_00568	1.29e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IFMFHLEA_00569	4.62e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IFMFHLEA_00570	1.56e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IFMFHLEA_00571	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IFMFHLEA_00572	3.52e-261	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IFMFHLEA_00573	1.83e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IFMFHLEA_00574	2.34e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IFMFHLEA_00575	2.03e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IFMFHLEA_00576	1.82e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IFMFHLEA_00577	6.61e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
IFMFHLEA_00578	1.45e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IFMFHLEA_00579	4.84e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IFMFHLEA_00580	3.95e-93	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IFMFHLEA_00581	5.41e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IFMFHLEA_00582	1.32e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IFMFHLEA_00583	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IFMFHLEA_00584	8e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IFMFHLEA_00585	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IFMFHLEA_00586	4.93e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IFMFHLEA_00587	1.71e-182	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IFMFHLEA_00588	1.02e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IFMFHLEA_00589	5.9e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IFMFHLEA_00590	4.09e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IFMFHLEA_00591	1.36e-39	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IFMFHLEA_00592	4.87e-193	ylmH	-	-	S	-	-	-	S4 domain protein
IFMFHLEA_00593	1.18e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IFMFHLEA_00594	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IFMFHLEA_00595	8.09e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IFMFHLEA_00596	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IFMFHLEA_00597	4.49e-42	-	-	-	-	-	-	-	-
IFMFHLEA_00598	1.02e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IFMFHLEA_00599	1.47e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IFMFHLEA_00600	1.62e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IFMFHLEA_00601	1.58e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
IFMFHLEA_00602	1.88e-134	-	-	-	S	-	-	-	repeat protein
IFMFHLEA_00603	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IFMFHLEA_00604	0.0	-	-	-	L	-	-	-	Nuclease-related domain
IFMFHLEA_00605	1.29e-233	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IFMFHLEA_00606	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFMFHLEA_00607	3.13e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IFMFHLEA_00608	2.52e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IFMFHLEA_00609	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IFMFHLEA_00610	2.75e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IFMFHLEA_00611	4.73e-69	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IFMFHLEA_00612	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IFMFHLEA_00613	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IFMFHLEA_00614	1.37e-246	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IFMFHLEA_00615	2.19e-131	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IFMFHLEA_00616	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IFMFHLEA_00617	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IFMFHLEA_00618	3.78e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IFMFHLEA_00619	4.08e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IFMFHLEA_00620	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFMFHLEA_00621	1.45e-195	-	-	-	-	-	-	-	-
IFMFHLEA_00622	8.19e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IFMFHLEA_00623	3.02e-294	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IFMFHLEA_00624	8.42e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IFMFHLEA_00625	1.17e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IFMFHLEA_00626	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IFMFHLEA_00627	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IFMFHLEA_00628	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IFMFHLEA_00629	1.39e-106	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IFMFHLEA_00630	5.48e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IFMFHLEA_00631	1.14e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IFMFHLEA_00632	1.23e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IFMFHLEA_00633	2.42e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IFMFHLEA_00634	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IFMFHLEA_00635	8.12e-262	pbpX1	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_00636	5.27e-57	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IFMFHLEA_00637	2.95e-307	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IFMFHLEA_00638	1.18e-55	-	-	-	C	-	-	-	FMN_bind
IFMFHLEA_00639	1.01e-104	-	-	-	-	-	-	-	-
IFMFHLEA_00640	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_00641	4.65e-228	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
IFMFHLEA_00642	5.52e-24	adhC	1.1.1.90	-	C	ko:K00055,ko:K06898	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	S-(hydroxymethyl)glutathione dehydrogenase activity
IFMFHLEA_00643	8.04e-188	-	-	-	-	-	-	-	-
IFMFHLEA_00647	1.93e-25	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
IFMFHLEA_00648	4.23e-93	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
IFMFHLEA_00649	3.08e-52	-	-	-	S	-	-	-	Transglycosylase associated protein
IFMFHLEA_00650	6.28e-10	-	-	-	S	-	-	-	CsbD-like
IFMFHLEA_00651	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_00652	1.62e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
IFMFHLEA_00653	4.98e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IFMFHLEA_00654	4.75e-80	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
IFMFHLEA_00655	4.68e-104	-	-	-	-	-	-	-	-
IFMFHLEA_00656	1.68e-179	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_00657	2.84e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IFMFHLEA_00658	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_00659	1.45e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IFMFHLEA_00660	1.91e-55	-	-	-	-	-	-	-	-
IFMFHLEA_00661	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_00662	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_00663	3.69e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IFMFHLEA_00664	1.01e-111	yfhC	-	-	C	-	-	-	Nitroreductase family
IFMFHLEA_00665	4.93e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IFMFHLEA_00666	2.12e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFMFHLEA_00667	1.19e-194	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IFMFHLEA_00668	2.64e-128	-	-	-	I	-	-	-	PAP2 superfamily
IFMFHLEA_00669	5.99e-244	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IFMFHLEA_00671	2.59e-229	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMFHLEA_00672	1.09e-34	-	-	-	-	-	-	-	-
IFMFHLEA_00673	1.05e-124	-	-	-	-	-	-	-	-
IFMFHLEA_00674	0.000281	-	-	-	-	-	-	-	-
IFMFHLEA_00675	9.27e-75	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IFMFHLEA_00676	2.16e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_00677	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IFMFHLEA_00678	6.63e-222	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IFMFHLEA_00679	1.53e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IFMFHLEA_00680	9.9e-84	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IFMFHLEA_00681	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IFMFHLEA_00682	1.03e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IFMFHLEA_00683	1.74e-199	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IFMFHLEA_00684	4.45e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00685	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IFMFHLEA_00686	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IFMFHLEA_00687	0.0	-	-	-	M	-	-	-	domain protein
IFMFHLEA_00688	5.14e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IFMFHLEA_00689	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IFMFHLEA_00690	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IFMFHLEA_00691	7.54e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IFMFHLEA_00692	7.35e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IFMFHLEA_00693	2.76e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
IFMFHLEA_00694	6.24e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
IFMFHLEA_00695	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IFMFHLEA_00697	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
IFMFHLEA_00698	6.03e-19	-	-	-	-	-	-	-	-
IFMFHLEA_00699	7.06e-166	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IFMFHLEA_00700	2.69e-43	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00701	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00702	4.42e-124	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IFMFHLEA_00703	2.09e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
IFMFHLEA_00704	5.21e-71	-	-	-	-	-	-	-	-
IFMFHLEA_00705	1.56e-228	citR	-	-	K	-	-	-	Putative sugar-binding domain
IFMFHLEA_00706	3.82e-312	-	-	-	S	-	-	-	Putative threonine/serine exporter
IFMFHLEA_00707	1.88e-111	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IFMFHLEA_00708	1.54e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IFMFHLEA_00709	1.17e-65	-	-	-	-	-	-	-	-
IFMFHLEA_00710	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IFMFHLEA_00711	2.56e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IFMFHLEA_00712	1.74e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IFMFHLEA_00713	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IFMFHLEA_00714	9.94e-287	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IFMFHLEA_00715	1.03e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IFMFHLEA_00716	2.72e-197	-	-	-	S	-	-	-	reductase
IFMFHLEA_00717	3.29e-193	yxeH	-	-	S	-	-	-	hydrolase
IFMFHLEA_00718	2.31e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFMFHLEA_00719	5.04e-298	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IFMFHLEA_00720	4.52e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
IFMFHLEA_00721	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IFMFHLEA_00722	3.01e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IFMFHLEA_00723	9.21e-273	oatA	-	-	I	-	-	-	Acyltransferase
IFMFHLEA_00724	6.51e-113	oatA	-	-	I	-	-	-	Acyltransferase
IFMFHLEA_00725	6.35e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IFMFHLEA_00726	1.5e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMFHLEA_00727	2.25e-45	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IFMFHLEA_00728	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IFMFHLEA_00729	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMFHLEA_00730	3.9e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IFMFHLEA_00731	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IFMFHLEA_00732	7.76e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IFMFHLEA_00733	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IFMFHLEA_00734	1e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IFMFHLEA_00735	2.19e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IFMFHLEA_00736	6.56e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMFHLEA_00737	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IFMFHLEA_00738	5.75e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IFMFHLEA_00739	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IFMFHLEA_00740	2.1e-18	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IFMFHLEA_00741	1.25e-105	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IFMFHLEA_00742	7.33e-71	-	-	-	M	-	-	-	Lysin motif
IFMFHLEA_00743	1.28e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IFMFHLEA_00744	4.07e-270	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IFMFHLEA_00745	3.15e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IFMFHLEA_00746	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IFMFHLEA_00747	2.22e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IFMFHLEA_00748	1.3e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFMFHLEA_00749	8.15e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IFMFHLEA_00750	4.94e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IFMFHLEA_00751	1.31e-96	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IFMFHLEA_00752	1.34e-77	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IFMFHLEA_00753	1.64e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IFMFHLEA_00754	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IFMFHLEA_00755	8.81e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IFMFHLEA_00756	8.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFMFHLEA_00757	1.07e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IFMFHLEA_00758	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IFMFHLEA_00759	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IFMFHLEA_00760	2.27e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IFMFHLEA_00761	3.29e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IFMFHLEA_00762	4.61e-308	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IFMFHLEA_00763	3.4e-230	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IFMFHLEA_00764	1.72e-85	-	-	-	-	-	-	-	-
IFMFHLEA_00765	4.82e-296	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_00766	1.25e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IFMFHLEA_00767	2.82e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IFMFHLEA_00768	7.42e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFMFHLEA_00769	9.18e-83	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFMFHLEA_00770	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IFMFHLEA_00771	0.0	-	-	-	E	-	-	-	Amino acid permease
IFMFHLEA_00772	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IFMFHLEA_00773	1.13e-312	ynbB	-	-	P	-	-	-	aluminum resistance
IFMFHLEA_00774	6.35e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
IFMFHLEA_00775	7.3e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IFMFHLEA_00776	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IFMFHLEA_00777	1.47e-105	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00778	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
IFMFHLEA_00779	4.33e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IFMFHLEA_00780	8.43e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
IFMFHLEA_00781	5.22e-89	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMFHLEA_00782	1.71e-265	-	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_00783	2.42e-201	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IFMFHLEA_00784	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IFMFHLEA_00785	1.84e-281	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IFMFHLEA_00786	5.05e-313	-	-	-	-	-	-	-	-
IFMFHLEA_00787	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_00788	2.78e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IFMFHLEA_00789	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IFMFHLEA_00790	5.68e-165	-	-	-	M	-	-	-	Glycosyl transferases group 1
IFMFHLEA_00791	5.84e-129	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IFMFHLEA_00792	7.57e-211	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IFMFHLEA_00793	2.61e-19	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IFMFHLEA_00794	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IFMFHLEA_00795	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IFMFHLEA_00796	9.5e-39	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IFMFHLEA_00797	1.72e-208	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
IFMFHLEA_00798	5.93e-149	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
IFMFHLEA_00799	5.96e-205	-	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_00800	2.55e-214	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
IFMFHLEA_00801	1.08e-212	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IFMFHLEA_00802	1.31e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
IFMFHLEA_00803	5.42e-275	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_00804	1.7e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMFHLEA_00807	2.77e-134	-	-	-	-	-	-	-	-
IFMFHLEA_00808	2.07e-102	-	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_00809	8.07e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IFMFHLEA_00810	3.34e-211	-	-	-	S	-	-	-	reductase
IFMFHLEA_00811	2.77e-220	-	-	-	-	-	-	-	-
IFMFHLEA_00812	4.2e-42	lysR	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_00813	3.25e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IFMFHLEA_00814	2.48e-131	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IFMFHLEA_00815	6.13e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_00816	3.59e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_00817	2.66e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IFMFHLEA_00818	1.72e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IFMFHLEA_00819	1.81e-223	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IFMFHLEA_00820	5.1e-43	-	-	-	-	-	-	-	-
IFMFHLEA_00821	1.41e-141	-	-	-	-	-	-	-	-
IFMFHLEA_00822	3.18e-140	-	-	-	-	-	-	-	-
IFMFHLEA_00823	3.18e-167	-	-	-	F	-	-	-	glutamine amidotransferase
IFMFHLEA_00824	9.73e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMFHLEA_00825	1.7e-199	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IFMFHLEA_00826	2.53e-152	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IFMFHLEA_00827	2.43e-100	-	-	-	-	-	-	-	-
IFMFHLEA_00828	1.24e-113	-	-	-	FG	-	-	-	HIT domain
IFMFHLEA_00829	5.21e-82	-	-	-	-	-	-	-	-
IFMFHLEA_00830	4.91e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IFMFHLEA_00831	1.62e-135	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IFMFHLEA_00832	6.2e-131	-	-	-	-	-	-	-	-
IFMFHLEA_00833	1.22e-103	-	-	-	-	-	-	-	-
IFMFHLEA_00834	2.72e-188	-	-	-	F	-	-	-	Phosphorylase superfamily
IFMFHLEA_00835	3.34e-139	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IFMFHLEA_00836	2.07e-189	-	-	-	F	-	-	-	Phosphorylase superfamily
IFMFHLEA_00837	1.04e-108	-	-	-	F	-	-	-	Phosphorylase superfamily
IFMFHLEA_00838	2.55e-64	-	-	-	F	-	-	-	Phosphorylase superfamily
IFMFHLEA_00839	1.79e-144	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
IFMFHLEA_00840	1.24e-47	-	-	-	-	-	-	-	-
IFMFHLEA_00841	2.58e-67	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IFMFHLEA_00842	9.6e-137	-	-	-	-	-	-	-	-
IFMFHLEA_00843	8.78e-52	-	-	-	-	-	-	-	-
IFMFHLEA_00844	3.77e-216	mleR	-	-	K	-	-	-	LysR family
IFMFHLEA_00845	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IFMFHLEA_00846	3.74e-130	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IFMFHLEA_00847	2.2e-310	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
IFMFHLEA_00848	2.27e-248	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IFMFHLEA_00849	5.33e-147	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IFMFHLEA_00850	1.23e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IFMFHLEA_00851	3.03e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IFMFHLEA_00852	2.55e-118	-	-	-	L	-	-	-	nuclease
IFMFHLEA_00853	2.51e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IFMFHLEA_00854	2.81e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IFMFHLEA_00855	4.76e-306	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IFMFHLEA_00856	4.4e-138	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IFMFHLEA_00857	6.01e-54	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IFMFHLEA_00858	3.16e-190	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IFMFHLEA_00859	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate carboxylase activity
IFMFHLEA_00860	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_00861	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_00862	2.29e-224	yobV3	-	-	K	-	-	-	WYL domain
IFMFHLEA_00863	4.35e-108	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
IFMFHLEA_00864	1.57e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
IFMFHLEA_00865	3.78e-72	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IFMFHLEA_00866	1.16e-148	-	-	-	C	-	-	-	Aldo/keto reductase family
IFMFHLEA_00867	7.12e-80	-	-	-	C	-	-	-	aldo keto reductase
IFMFHLEA_00868	1.54e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
IFMFHLEA_00869	1.51e-24	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00871	9.87e-139	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00872	2.88e-130	-	-	-	P	-	-	-	esterase
IFMFHLEA_00873	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IFMFHLEA_00874	3.77e-32	-	-	-	-	-	-	-	-
IFMFHLEA_00875	1.29e-182	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00876	7.38e-127	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IFMFHLEA_00877	3.1e-30	-	-	-	C	-	-	-	Flavodoxin
IFMFHLEA_00878	1.39e-190	-	-	-	P	-	-	-	FAD-binding domain
IFMFHLEA_00879	2.54e-101	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IFMFHLEA_00881	0.0	yagE	-	-	E	-	-	-	amino acid
IFMFHLEA_00882	1.37e-15	-	-	-	S	-	-	-	Alpha beta hydrolase
IFMFHLEA_00883	6e-59	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMFHLEA_00884	4.13e-18	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMFHLEA_00885	1.43e-24	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
IFMFHLEA_00886	8.53e-215	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IFMFHLEA_00887	1.17e-130	-	-	-	-	-	-	-	-
IFMFHLEA_00888	1.9e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFMFHLEA_00889	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFMFHLEA_00890	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFMFHLEA_00891	6.17e-236	-	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_00892	3.65e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IFMFHLEA_00893	7.02e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFMFHLEA_00894	9.73e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
IFMFHLEA_00895	4.78e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IFMFHLEA_00896	3.46e-87	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IFMFHLEA_00898	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_00899	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_00900	1.74e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IFMFHLEA_00901	1.06e-110	rmaD	-	-	K	-	-	-	transcriptional
IFMFHLEA_00902	3.92e-76	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IFMFHLEA_00903	3.43e-07	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IFMFHLEA_00904	2.71e-256	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IFMFHLEA_00905	2.62e-138	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
IFMFHLEA_00906	1.27e-119	flaR	-	-	F	-	-	-	topology modulation protein
IFMFHLEA_00907	1.03e-100	-	-	-	-	-	-	-	-
IFMFHLEA_00908	5.95e-250	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IFMFHLEA_00909	7.16e-71	-	-	-	S	-	-	-	EDD domain protein, DegV family
IFMFHLEA_00910	7.03e-104	-	-	-	S	-	-	-	EDD domain protein, DegV family
IFMFHLEA_00911	2.95e-87	-	-	-	-	-	-	-	-
IFMFHLEA_00912	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IFMFHLEA_00913	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IFMFHLEA_00914	2.05e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IFMFHLEA_00915	2.88e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IFMFHLEA_00916	6.23e-113	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IFMFHLEA_00917	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IFMFHLEA_00918	2.01e-310	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IFMFHLEA_00919	2.39e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IFMFHLEA_00920	2.83e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IFMFHLEA_00921	1.61e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IFMFHLEA_00922	1.99e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IFMFHLEA_00923	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IFMFHLEA_00924	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IFMFHLEA_00925	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IFMFHLEA_00926	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IFMFHLEA_00927	8.23e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IFMFHLEA_00928	7.05e-284	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IFMFHLEA_00929	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IFMFHLEA_00930	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IFMFHLEA_00931	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IFMFHLEA_00932	6.78e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IFMFHLEA_00933	3.39e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IFMFHLEA_00934	1.64e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IFMFHLEA_00935	2.09e-242	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IFMFHLEA_00936	1.01e-187	-	-	-	K	-	-	-	SIS domain
IFMFHLEA_00937	1.18e-140	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IFMFHLEA_00938	2.04e-73	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IFMFHLEA_00939	1.14e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IFMFHLEA_00940	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IFMFHLEA_00941	1.05e-228	-	-	-	-	-	-	-	-
IFMFHLEA_00942	1.57e-181	-	-	-	-	-	-	-	-
IFMFHLEA_00943	1.72e-123	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMFHLEA_00944	1.04e-37	-	-	-	-	-	-	-	-
IFMFHLEA_00945	3.64e-175	-	-	-	-	-	-	-	-
IFMFHLEA_00946	2.03e-186	-	-	-	-	-	-	-	-
IFMFHLEA_00947	1.51e-174	-	-	-	-	-	-	-	-
IFMFHLEA_00948	1.09e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IFMFHLEA_00949	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IFMFHLEA_00950	7.64e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IFMFHLEA_00951	3.45e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IFMFHLEA_00952	4.48e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IFMFHLEA_00953	1.87e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IFMFHLEA_00954	2.24e-162	-	-	-	S	-	-	-	Peptidase family M23
IFMFHLEA_00955	3.01e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IFMFHLEA_00956	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IFMFHLEA_00957	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IFMFHLEA_00958	1.05e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IFMFHLEA_00959	5.41e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IFMFHLEA_00960	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IFMFHLEA_00961	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IFMFHLEA_00962	1.82e-226	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IFMFHLEA_00963	4.38e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IFMFHLEA_00964	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IFMFHLEA_00965	2.71e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IFMFHLEA_00966	3.22e-133	-	-	-	S	-	-	-	Peptidase family M23
IFMFHLEA_00967	6.31e-144	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IFMFHLEA_00968	2.17e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFMFHLEA_00969	1.4e-157	-	-	-	-	-	-	-	-
IFMFHLEA_00970	4.04e-207	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IFMFHLEA_00971	1.58e-282	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IFMFHLEA_00972	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IFMFHLEA_00973	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IFMFHLEA_00974	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IFMFHLEA_00975	3.65e-28	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IFMFHLEA_00976	1.92e-141	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IFMFHLEA_00977	0.0	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
IFMFHLEA_00978	2.86e-05	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
IFMFHLEA_00979	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IFMFHLEA_00980	5.4e-282	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IFMFHLEA_00981	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_00982	3.69e-157	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
IFMFHLEA_00983	8.29e-129	-	-	-	-	-	-	-	-
IFMFHLEA_00984	1.82e-139	-	-	-	K	-	-	-	LysR substrate binding domain
IFMFHLEA_00985	8.62e-22	-	-	-	-	-	-	-	-
IFMFHLEA_00986	3.35e-291	-	-	-	S	-	-	-	Sterol carrier protein domain
IFMFHLEA_00987	3.83e-127	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IFMFHLEA_00988	4.54e-95	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IFMFHLEA_00989	1.32e-90	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IFMFHLEA_00990	2.3e-100	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IFMFHLEA_00991	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IFMFHLEA_00992	1.19e-113	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
IFMFHLEA_00993	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFMFHLEA_00994	4.53e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IFMFHLEA_00995	1.73e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IFMFHLEA_00996	1.72e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
IFMFHLEA_00997	6.15e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IFMFHLEA_00999	7.02e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMFHLEA_01000	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IFMFHLEA_01001	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IFMFHLEA_01002	6.07e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IFMFHLEA_01003	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IFMFHLEA_01004	5.85e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IFMFHLEA_01005	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IFMFHLEA_01006	7.55e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IFMFHLEA_01007	2.1e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IFMFHLEA_01008	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IFMFHLEA_01009	2.49e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IFMFHLEA_01010	8.54e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IFMFHLEA_01011	9.65e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IFMFHLEA_01012	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IFMFHLEA_01013	3.95e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
IFMFHLEA_01014	6.47e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IFMFHLEA_01015	3.76e-268	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IFMFHLEA_01016	2.39e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IFMFHLEA_01017	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFMFHLEA_01018	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IFMFHLEA_01019	1.35e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IFMFHLEA_01020	1.89e-188	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IFMFHLEA_01021	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IFMFHLEA_01022	2.53e-114	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IFMFHLEA_01023	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IFMFHLEA_01024	1.45e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IFMFHLEA_01025	2.05e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IFMFHLEA_01026	6.34e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IFMFHLEA_01027	1.59e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IFMFHLEA_01028	9.32e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IFMFHLEA_01029	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IFMFHLEA_01030	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01031	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01032	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IFMFHLEA_01033	2.97e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
IFMFHLEA_01034	2.83e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IFMFHLEA_01035	1.4e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IFMFHLEA_01036	1.19e-156	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
IFMFHLEA_01037	2.58e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IFMFHLEA_01038	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IFMFHLEA_01039	2.48e-91	-	-	-	S	-	-	-	GtrA-like protein
IFMFHLEA_01040	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IFMFHLEA_01041	5.01e-164	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IFMFHLEA_01042	1.07e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IFMFHLEA_01043	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IFMFHLEA_01044	1.9e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IFMFHLEA_01045	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IFMFHLEA_01046	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
IFMFHLEA_01047	1.16e-88	-	-	-	-	-	-	-	-
IFMFHLEA_01048	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IFMFHLEA_01049	1.12e-228	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IFMFHLEA_01050	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IFMFHLEA_01051	4.48e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IFMFHLEA_01052	5.77e-307	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
IFMFHLEA_01053	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IFMFHLEA_01054	3.62e-121	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IFMFHLEA_01055	4.92e-207	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IFMFHLEA_01056	1.84e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IFMFHLEA_01057	1.47e-144	-	-	-	S	-	-	-	SNARE associated Golgi protein
IFMFHLEA_01058	1.28e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IFMFHLEA_01059	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IFMFHLEA_01060	9.18e-112	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IFMFHLEA_01064	9.93e-210	-	-	-	M	-	-	-	Rib/alpha-like repeat
IFMFHLEA_01066	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_01067	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_01068	5.84e-202	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_01069	1.49e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01070	8.73e-234	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01071	1.43e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01072	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IFMFHLEA_01073	3.16e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IFMFHLEA_01074	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IFMFHLEA_01075	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IFMFHLEA_01076	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IFMFHLEA_01077	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IFMFHLEA_01078	1.5e-68	-	-	-	-	-	-	-	-
IFMFHLEA_01079	3.29e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IFMFHLEA_01080	5.27e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IFMFHLEA_01081	3.81e-102	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IFMFHLEA_01082	3.84e-100	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IFMFHLEA_01083	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IFMFHLEA_01084	9.79e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IFMFHLEA_01085	4.61e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IFMFHLEA_01086	1.08e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IFMFHLEA_01087	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IFMFHLEA_01088	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IFMFHLEA_01089	2.53e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IFMFHLEA_01090	2.88e-105	-	-	-	S	-	-	-	ASCH
IFMFHLEA_01091	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IFMFHLEA_01092	1.52e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IFMFHLEA_01093	1.84e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IFMFHLEA_01094	3.76e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFMFHLEA_01095	5.86e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFMFHLEA_01096	5.91e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IFMFHLEA_01097	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IFMFHLEA_01098	2.57e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IFMFHLEA_01099	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFMFHLEA_01100	3.69e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IFMFHLEA_01101	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IFMFHLEA_01102	4.8e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IFMFHLEA_01103	3.54e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFMFHLEA_01104	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IFMFHLEA_01105	3.98e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IFMFHLEA_01106	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IFMFHLEA_01107	4.41e-137	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
IFMFHLEA_01108	9.64e-141	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
IFMFHLEA_01109	7.45e-09	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01110	9.58e-80	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01111	7.38e-127	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01112	3.88e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
IFMFHLEA_01113	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IFMFHLEA_01114	3.04e-198	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
IFMFHLEA_01115	3.74e-244	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IFMFHLEA_01117	4.22e-211	-	-	-	S	-	-	-	Membrane
IFMFHLEA_01118	1.75e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
IFMFHLEA_01119	4.8e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IFMFHLEA_01120	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_01121	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_01122	1.84e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IFMFHLEA_01123	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_01124	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
IFMFHLEA_01125	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
IFMFHLEA_01126	0.0	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_01127	7.89e-213	-	2.7.1.85	-	GK	ko:K18673	-	ko00000,ko01000	ROK family
IFMFHLEA_01128	3.58e-262	xylR	-	-	GK	-	-	-	ROK family
IFMFHLEA_01129	4.89e-301	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_01130	9.35e-128	-	-	-	S	-	-	-	Bacterial PH domain
IFMFHLEA_01131	3.5e-22	-	-	-	-	-	-	-	-
IFMFHLEA_01132	1.02e-85	-	-	-	K	-	-	-	sequence-specific DNA binding
IFMFHLEA_01133	2.45e-63	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
IFMFHLEA_01134	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IFMFHLEA_01135	1.67e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IFMFHLEA_01136	2.43e-62	-	-	-	-	-	-	-	-
IFMFHLEA_01137	1.74e-192	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IFMFHLEA_01138	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_01139	2.73e-07	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IFMFHLEA_01140	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IFMFHLEA_01141	2.85e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IFMFHLEA_01142	1.47e-191	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IFMFHLEA_01143	8.15e-69	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IFMFHLEA_01144	3.43e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IFMFHLEA_01145	1.75e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFMFHLEA_01146	1.71e-33	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IFMFHLEA_01147	2.33e-164	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IFMFHLEA_01148	7.44e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IFMFHLEA_01149	9.13e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IFMFHLEA_01150	3.3e-152	-	-	-	GM	-	-	-	NmrA-like family
IFMFHLEA_01151	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IFMFHLEA_01152	9.28e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IFMFHLEA_01153	1.86e-141	-	-	-	O	-	-	-	Matrixin
IFMFHLEA_01154	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IFMFHLEA_01155	3.89e-122	-	-	-	K	-	-	-	acetyltransferase
IFMFHLEA_01156	1.65e-66	-	-	-	-	-	-	-	-
IFMFHLEA_01157	2.34e-204	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IFMFHLEA_01158	2.87e-62	-	-	-	-	-	-	-	-
IFMFHLEA_01159	7.22e-161	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IFMFHLEA_01160	1.15e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IFMFHLEA_01161	2.66e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IFMFHLEA_01162	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_01164	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
IFMFHLEA_01165	7.81e-82	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
IFMFHLEA_01166	3.88e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IFMFHLEA_01167	1.77e-150	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IFMFHLEA_01168	2.97e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IFMFHLEA_01169	8.85e-85	-	-	-	S	-	-	-	ASCH domain
IFMFHLEA_01170	6.71e-153	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
IFMFHLEA_01172	5.31e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IFMFHLEA_01173	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
IFMFHLEA_01176	2.26e-267	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
IFMFHLEA_01177	1.63e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IFMFHLEA_01178	8.74e-192	-	-	-	T	-	-	-	EAL domain
IFMFHLEA_01179	3.81e-58	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
IFMFHLEA_01180	4.05e-233	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
IFMFHLEA_01181	3.07e-119	-	-	-	-	-	-	-	-
IFMFHLEA_01182	9.37e-227	-	-	-	C	-	-	-	Oxidoreductase
IFMFHLEA_01184	4.69e-271	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
IFMFHLEA_01185	4.27e-37	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
IFMFHLEA_01186	4.83e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
IFMFHLEA_01187	2.86e-19	-	-	-	-	-	-	-	-
IFMFHLEA_01188	0.0	potE	-	-	E	-	-	-	Amino Acid
IFMFHLEA_01189	2.05e-163	-	-	-	S	-	-	-	Alpha beta hydrolase
IFMFHLEA_01191	1.31e-165	-	-	-	-	-	-	-	-
IFMFHLEA_01192	5.44e-163	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
IFMFHLEA_01193	8.84e-93	-	-	-	O	-	-	-	OsmC-like protein
IFMFHLEA_01194	3.65e-272	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMFHLEA_01195	5.46e-297	sptS	-	-	T	-	-	-	Histidine kinase
IFMFHLEA_01196	1.28e-152	dltr	-	-	K	-	-	-	response regulator
IFMFHLEA_01197	4.2e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IFMFHLEA_01198	7.55e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
IFMFHLEA_01199	1.31e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
IFMFHLEA_01200	8.2e-81	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
IFMFHLEA_01201	1.63e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IFMFHLEA_01202	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
IFMFHLEA_01203	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IFMFHLEA_01204	3.33e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01205	7.19e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_01206	1.98e-200	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_01207	6.26e-309	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMFHLEA_01208	2.43e-204	lacR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMFHLEA_01209	2.78e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IFMFHLEA_01210	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IFMFHLEA_01211	4.02e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IFMFHLEA_01212	9.46e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
IFMFHLEA_01213	1.53e-61	-	-	-	-	-	-	-	-
IFMFHLEA_01215	3.46e-53	-	-	-	C	-	-	-	FMN binding
IFMFHLEA_01216	1.42e-215	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_01217	5.56e-246	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IFMFHLEA_01218	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IFMFHLEA_01219	1.45e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IFMFHLEA_01220	9.91e-241	-	-	-	M	-	-	-	domain protein
IFMFHLEA_01221	1.51e-145	-	-	-	-	-	-	-	-
IFMFHLEA_01222	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
IFMFHLEA_01223	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IFMFHLEA_01224	1.31e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IFMFHLEA_01231	7.66e-181	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
IFMFHLEA_01232	8.39e-146	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
IFMFHLEA_01233	6.91e-235	-	-	-	-	-	-	-	-
IFMFHLEA_01234	4.05e-119	-	-	-	-	-	-	-	-
IFMFHLEA_01235	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
IFMFHLEA_01237	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
IFMFHLEA_01238	4.37e-205	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IFMFHLEA_01239	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_01240	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_01241	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_01242	1.24e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IFMFHLEA_01243	2.88e-107	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IFMFHLEA_01244	1.61e-134	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IFMFHLEA_01245	1.96e-192	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IFMFHLEA_01246	3.86e-239	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMFHLEA_01247	7.86e-240	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMFHLEA_01248	1.71e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IFMFHLEA_01249	1.56e-256	-	-	-	S	-	-	-	Membrane
IFMFHLEA_01250	5.59e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IFMFHLEA_01251	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
IFMFHLEA_01252	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
IFMFHLEA_01255	3.39e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IFMFHLEA_01256	1.6e-119	-	-	-	-	-	-	-	-
IFMFHLEA_01257	8.44e-201	-	-	-	-	-	-	-	-
IFMFHLEA_01258	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IFMFHLEA_01259	7.07e-178	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IFMFHLEA_01260	1.35e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
IFMFHLEA_01261	1.25e-22	-	-	-	-	-	-	-	-
IFMFHLEA_01262	3.45e-64	-	-	-	-	-	-	-	-
IFMFHLEA_01263	3.66e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IFMFHLEA_01264	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IFMFHLEA_01265	2.15e-50	-	-	-	-	-	-	-	-
IFMFHLEA_01266	8.94e-26	-	-	-	-	-	-	-	-
IFMFHLEA_01267	7.62e-308	-	-	-	S	-	-	-	response to antibiotic
IFMFHLEA_01268	3.02e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01269	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IFMFHLEA_01270	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IFMFHLEA_01271	4.01e-90	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IFMFHLEA_01272	8.71e-33	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IFMFHLEA_01273	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IFMFHLEA_01274	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01275	1.29e-140	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IFMFHLEA_01276	2.71e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IFMFHLEA_01277	1.25e-106	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IFMFHLEA_01278	1.68e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMFHLEA_01279	3.51e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IFMFHLEA_01280	8.57e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFMFHLEA_01281	9.2e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IFMFHLEA_01282	2.28e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IFMFHLEA_01283	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IFMFHLEA_01284	3.59e-123	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IFMFHLEA_01285	4.9e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
IFMFHLEA_01286	1.34e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IFMFHLEA_01287	2.36e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IFMFHLEA_01288	1.47e-310	-	-	-	T	-	-	-	GHKL domain
IFMFHLEA_01289	2.91e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IFMFHLEA_01290	5.44e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IFMFHLEA_01291	1.85e-246	-	-	-	V	-	-	-	ABC transporter transmembrane region
IFMFHLEA_01292	3.75e-111	-	-	-	V	-	-	-	ABC transporter transmembrane region
IFMFHLEA_01293	9.1e-184	-	-	-	S	-	-	-	PAS domain
IFMFHLEA_01294	7.95e-64	-	-	-	-	-	-	-	-
IFMFHLEA_01295	0.0	-	-	-	-	-	-	-	-
IFMFHLEA_01296	3.05e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IFMFHLEA_01297	0.0	-	-	-	M	-	-	-	domain protein
IFMFHLEA_01298	9.54e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IFMFHLEA_01299	7.21e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMFHLEA_01300	4.72e-200	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IFMFHLEA_01301	4e-234	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
IFMFHLEA_01302	4.53e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IFMFHLEA_01303	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IFMFHLEA_01304	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IFMFHLEA_01305	1.24e-197	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
IFMFHLEA_01306	1.68e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_01307	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
IFMFHLEA_01308	2.47e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMFHLEA_01309	7.19e-202	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IFMFHLEA_01310	2.62e-198	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IFMFHLEA_01311	1.8e-124	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMFHLEA_01312	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IFMFHLEA_01313	6.9e-220	-	-	-	-	-	-	-	-
IFMFHLEA_01314	2.53e-283	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IFMFHLEA_01315	7.59e-269	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IFMFHLEA_01316	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IFMFHLEA_01317	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IFMFHLEA_01318	4.62e-181	-	-	-	-	-	-	-	-
IFMFHLEA_01319	2.12e-176	-	-	-	-	-	-	-	-
IFMFHLEA_01320	1.84e-170	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IFMFHLEA_01321	8.51e-143	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IFMFHLEA_01322	1.96e-132	-	-	-	G	-	-	-	Aldose 1-epimerase
IFMFHLEA_01323	1.34e-259	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IFMFHLEA_01324	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFMFHLEA_01325	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
IFMFHLEA_01326	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
IFMFHLEA_01327	6.28e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFMFHLEA_01328	1.02e-74	-	-	-	-	-	-	-	-
IFMFHLEA_01330	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IFMFHLEA_01331	1.16e-162	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IFMFHLEA_01332	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IFMFHLEA_01333	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IFMFHLEA_01334	8.86e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFMFHLEA_01335	5.46e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMFHLEA_01336	1.92e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMFHLEA_01337	1.9e-256	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01338	1.87e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01339	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IFMFHLEA_01340	1.5e-96	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IFMFHLEA_01341	6.92e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFMFHLEA_01342	1.09e-148	-	-	-	-	-	-	-	-
IFMFHLEA_01344	1.21e-146	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
IFMFHLEA_01345	2.35e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IFMFHLEA_01346	2.69e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
IFMFHLEA_01347	1.25e-142	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IFMFHLEA_01348	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IFMFHLEA_01349	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IFMFHLEA_01350	2.33e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IFMFHLEA_01351	1.63e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IFMFHLEA_01352	4.9e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IFMFHLEA_01353	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IFMFHLEA_01354	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IFMFHLEA_01355	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IFMFHLEA_01356	1.4e-116	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_01357	4.55e-117	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_01358	1.48e-114	-	-	-	-	-	-	-	-
IFMFHLEA_01359	0.0	-	-	-	S	-	-	-	SLAP domain
IFMFHLEA_01360	2.68e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFMFHLEA_01361	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMFHLEA_01362	3.82e-167	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IFMFHLEA_01363	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_01364	4.58e-216	-	-	-	GK	-	-	-	ROK family
IFMFHLEA_01365	4.88e-59	-	-	-	-	-	-	-	-
IFMFHLEA_01366	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IFMFHLEA_01367	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IFMFHLEA_01368	1.11e-96	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IFMFHLEA_01369	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IFMFHLEA_01370	6.32e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFMFHLEA_01371	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IFMFHLEA_01372	7.87e-207	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
IFMFHLEA_01373	8.61e-139	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IFMFHLEA_01374	1.21e-285	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IFMFHLEA_01375	5.8e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IFMFHLEA_01376	1.04e-173	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IFMFHLEA_01377	3.77e-220	-	-	-	K	-	-	-	Helix-turn-helix
IFMFHLEA_01378	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IFMFHLEA_01379	7.77e-199	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMFHLEA_01380	3.12e-191	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IFMFHLEA_01381	2.08e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
IFMFHLEA_01382	1.16e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IFMFHLEA_01383	7.88e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMFHLEA_01384	9.09e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
IFMFHLEA_01385	2.07e-117	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
IFMFHLEA_01386	2.89e-44	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
IFMFHLEA_01387	5.49e-42	-	-	-	-	-	-	-	-
IFMFHLEA_01388	3.18e-106	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IFMFHLEA_01389	6.74e-39	-	-	-	K	ko:K12410	-	ko00000,ko01000	NAD+ binding
IFMFHLEA_01390	4.62e-13	-	-	-	P	-	-	-	Voltage gated chloride channel
IFMFHLEA_01391	7.47e-126	-	-	-	-	-	-	-	-
IFMFHLEA_01392	8.2e-68	-	-	-	-	-	-	-	-
IFMFHLEA_01393	4.88e-59	-	-	-	-	-	-	-	-
IFMFHLEA_01394	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IFMFHLEA_01395	0.0	-	-	-	E	-	-	-	amino acid
IFMFHLEA_01396	9.8e-204	supH	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IFMFHLEA_01397	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IFMFHLEA_01398	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IFMFHLEA_01399	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IFMFHLEA_01400	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IFMFHLEA_01401	3.27e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IFMFHLEA_01402	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IFMFHLEA_01403	1.44e-165	-	-	-	S	-	-	-	(CBS) domain
IFMFHLEA_01404	1.98e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IFMFHLEA_01405	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IFMFHLEA_01406	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IFMFHLEA_01407	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IFMFHLEA_01408	1.79e-46	yabO	-	-	J	-	-	-	S4 domain protein
IFMFHLEA_01409	1.03e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IFMFHLEA_01410	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
IFMFHLEA_01411	5.11e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IFMFHLEA_01412	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IFMFHLEA_01413	6.77e-215	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IFMFHLEA_01414	3.5e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IFMFHLEA_01415	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IFMFHLEA_01419	1.16e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IFMFHLEA_01420	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IFMFHLEA_01421	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMFHLEA_01422	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMFHLEA_01423	6.6e-159	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IFMFHLEA_01424	2.09e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IFMFHLEA_01425	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IFMFHLEA_01426	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IFMFHLEA_01427	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IFMFHLEA_01428	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IFMFHLEA_01429	1.91e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IFMFHLEA_01430	7.21e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IFMFHLEA_01431	9.85e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IFMFHLEA_01432	1.34e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IFMFHLEA_01433	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IFMFHLEA_01434	7.15e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IFMFHLEA_01435	9.64e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IFMFHLEA_01436	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IFMFHLEA_01437	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IFMFHLEA_01438	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IFMFHLEA_01439	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IFMFHLEA_01440	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IFMFHLEA_01441	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFMFHLEA_01442	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IFMFHLEA_01443	2.5e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IFMFHLEA_01444	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IFMFHLEA_01445	5.3e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IFMFHLEA_01446	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IFMFHLEA_01447	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IFMFHLEA_01448	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IFMFHLEA_01449	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IFMFHLEA_01450	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IFMFHLEA_01451	4.63e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IFMFHLEA_01452	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IFMFHLEA_01453	3.95e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IFMFHLEA_01454	2.55e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMFHLEA_01455	1.57e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IFMFHLEA_01456	4.16e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMFHLEA_01457	4.04e-206	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMFHLEA_01458	1.74e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMFHLEA_01459	4.17e-192	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IFMFHLEA_01460	1.6e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IFMFHLEA_01461	8.28e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IFMFHLEA_01462	5.27e-16	-	-	-	-	-	-	-	-
IFMFHLEA_01463	3.63e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IFMFHLEA_01464	4.67e-154	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IFMFHLEA_01465	8.09e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IFMFHLEA_01466	6.91e-164	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IFMFHLEA_01467	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IFMFHLEA_01468	1.14e-27	-	-	-	-	-	-	-	-
IFMFHLEA_01469	1.27e-104	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IFMFHLEA_01470	9.84e-236	-	-	-	S	-	-	-	AAA domain
IFMFHLEA_01471	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IFMFHLEA_01472	9.95e-70	-	-	-	-	-	-	-	-
IFMFHLEA_01473	1.82e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IFMFHLEA_01474	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IFMFHLEA_01475	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IFMFHLEA_01476	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IFMFHLEA_01477	6.01e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IFMFHLEA_01478	8.7e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFMFHLEA_01479	2.91e-121	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IFMFHLEA_01480	2.41e-45	-	-	-	-	-	-	-	-
IFMFHLEA_01481	6.48e-148	-	-	-	-	-	-	-	-
IFMFHLEA_01482	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IFMFHLEA_01483	1.22e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMFHLEA_01484	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IFMFHLEA_01485	1.72e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IFMFHLEA_01486	3.66e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IFMFHLEA_01487	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IFMFHLEA_01488	1.5e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IFMFHLEA_01489	2.83e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IFMFHLEA_01490	1.8e-223	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IFMFHLEA_01491	4.47e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IFMFHLEA_01492	4.47e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFMFHLEA_01493	5.67e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFMFHLEA_01494	1.74e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IFMFHLEA_01495	3.62e-268	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IFMFHLEA_01496	1.86e-38	-	-	-	-	-	-	-	-
IFMFHLEA_01497	2.15e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IFMFHLEA_01498	9.31e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IFMFHLEA_01499	3.83e-167	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
IFMFHLEA_01500	1.25e-147	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IFMFHLEA_01501	4.9e-33	-	-	-	-	-	-	-	-
IFMFHLEA_01502	1.31e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IFMFHLEA_01503	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFMFHLEA_01504	6e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMFHLEA_01505	1.35e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMFHLEA_01506	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMFHLEA_01507	8.05e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01508	2.56e-110	-	-	-	-	-	-	-	-
IFMFHLEA_01509	2.49e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_01512	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
IFMFHLEA_01513	1.53e-118	ymdB	-	-	S	-	-	-	Macro domain protein
IFMFHLEA_01514	1.97e-280	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IFMFHLEA_01516	8.59e-148	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IFMFHLEA_01517	3e-133	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMFHLEA_01518	9.68e-226	-	-	-	-	-	-	-	-
IFMFHLEA_01519	7.67e-80	lysM	-	-	M	-	-	-	LysM domain
IFMFHLEA_01520	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IFMFHLEA_01521	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IFMFHLEA_01522	2.13e-36	-	-	-	-	-	-	-	-
IFMFHLEA_01523	1.71e-282	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IFMFHLEA_01524	3.08e-204	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
IFMFHLEA_01525	3.44e-153	-	-	-	-	-	-	-	-
IFMFHLEA_01526	4.33e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IFMFHLEA_01527	1.19e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
IFMFHLEA_01528	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
IFMFHLEA_01529	1.45e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMFHLEA_01530	1.43e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01531	3.26e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01532	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IFMFHLEA_01533	1.59e-49	-	-	-	-	-	-	-	-
IFMFHLEA_01534	2.15e-144	-	-	-	K	-	-	-	WHG domain
IFMFHLEA_01535	4.14e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IFMFHLEA_01536	6.34e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IFMFHLEA_01537	9.1e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IFMFHLEA_01538	6.64e-233	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IFMFHLEA_01539	8.5e-105	cvpA	-	-	S	-	-	-	Colicin V production protein
IFMFHLEA_01540	3.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IFMFHLEA_01541	2.79e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IFMFHLEA_01542	4.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IFMFHLEA_01543	2.05e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IFMFHLEA_01544	2.22e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IFMFHLEA_01545	1.39e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IFMFHLEA_01546	1.55e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IFMFHLEA_01547	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01548	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IFMFHLEA_01549	1.44e-157	vanR	-	-	K	-	-	-	response regulator
IFMFHLEA_01550	9.58e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IFMFHLEA_01551	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IFMFHLEA_01552	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IFMFHLEA_01553	5.63e-64	-	-	-	S	-	-	-	Enterocin A Immunity
IFMFHLEA_01554	1.4e-69	-	-	-	S	-	-	-	Enterocin A Immunity
IFMFHLEA_01555	1.31e-32	-	-	-	-	-	-	-	-
IFMFHLEA_01556	9.17e-37	-	-	-	-	-	-	-	-
IFMFHLEA_01557	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
IFMFHLEA_01558	2.62e-50	-	-	-	S	-	-	-	Enterocin A Immunity
IFMFHLEA_01559	5.21e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMFHLEA_01560	2.71e-136	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMFHLEA_01562	2.6e-141	-	-	-	-	-	-	-	-
IFMFHLEA_01565	2e-06	-	-	-	-	-	-	-	-
IFMFHLEA_01566	4.67e-297	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IFMFHLEA_01567	7.63e-190	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IFMFHLEA_01570	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IFMFHLEA_01571	3.21e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
IFMFHLEA_01572	1.21e-275	blpT	-	-	-	-	-	-	-
IFMFHLEA_01577	2.26e-29	-	-	-	-	-	-	-	-
IFMFHLEA_01578	9.7e-116	-	-	-	-	-	-	-	-
IFMFHLEA_01579	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IFMFHLEA_01580	6.68e-35	-	-	-	-	-	-	-	-
IFMFHLEA_01581	4.14e-89	-	-	-	-	-	-	-	-
IFMFHLEA_01582	2.89e-12	-	-	-	-	-	-	-	-
IFMFHLEA_01583	1.6e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01584	1.22e-274	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IFMFHLEA_01585	6.57e-252	-	-	-	S	-	-	-	Fic/DOC family
IFMFHLEA_01586	1.49e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IFMFHLEA_01587	1.31e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IFMFHLEA_01588	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IFMFHLEA_01589	4.7e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IFMFHLEA_01590	3e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
IFMFHLEA_01591	7.83e-60	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMFHLEA_01592	1.79e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IFMFHLEA_01593	6.65e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMFHLEA_01594	6.99e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IFMFHLEA_01595	1.04e-82	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IFMFHLEA_01596	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IFMFHLEA_01597	9.86e-59	-	-	-	P	ko:K03449	-	ko00000,ko02000	transmembrane transport
IFMFHLEA_01598	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IFMFHLEA_01599	5.01e-293	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IFMFHLEA_01600	2.7e-59	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IFMFHLEA_01601	3.08e-81	-	-	-	-	-	-	-	-
IFMFHLEA_01602	0.0	-	-	-	S	-	-	-	ABC transporter
IFMFHLEA_01603	3.12e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
IFMFHLEA_01604	4.44e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IFMFHLEA_01605	1.68e-18	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IFMFHLEA_01606	1.08e-62	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IFMFHLEA_01607	1.47e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IFMFHLEA_01608	3.7e-175	-	-	-	S	-	-	-	Peptidase_C39 like family
IFMFHLEA_01609	1.36e-105	-	-	-	-	-	-	-	-
IFMFHLEA_01610	2.71e-233	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFMFHLEA_01611	7.02e-103	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
IFMFHLEA_01612	4.7e-143	-	-	-	-	-	-	-	-
IFMFHLEA_01613	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
IFMFHLEA_01614	2.96e-56	-	-	-	-	-	-	-	-
IFMFHLEA_01615	6.94e-110	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
IFMFHLEA_01616	7.09e-125	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IFMFHLEA_01617	2.99e-176	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IFMFHLEA_01618	1.4e-204	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IFMFHLEA_01619	0.0	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
IFMFHLEA_01620	5.52e-241	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
IFMFHLEA_01621	1.42e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IFMFHLEA_01622	5.44e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IFMFHLEA_01623	1.01e-193	epsB	-	-	M	-	-	-	biosynthesis protein
IFMFHLEA_01624	4.87e-165	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IFMFHLEA_01625	7.21e-190	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IFMFHLEA_01626	1.77e-159	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IFMFHLEA_01627	4.02e-192	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IFMFHLEA_01628	2.65e-215	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
IFMFHLEA_01629	2.89e-150	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IFMFHLEA_01630	7.58e-244	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
IFMFHLEA_01631	1.86e-287	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IFMFHLEA_01632	1.23e-255	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IFMFHLEA_01633	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IFMFHLEA_01634	1.34e-298	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IFMFHLEA_01635	1.63e-175	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IFMFHLEA_01636	2.52e-84	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IFMFHLEA_01637	1.23e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IFMFHLEA_01638	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IFMFHLEA_01639	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IFMFHLEA_01640	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IFMFHLEA_01641	7.42e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFMFHLEA_01642	7.43e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IFMFHLEA_01643	7.79e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IFMFHLEA_01644	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IFMFHLEA_01645	4.8e-99	-	-	-	-	-	-	-	-
IFMFHLEA_01646	1.06e-20	-	-	-	-	-	-	-	-
IFMFHLEA_01647	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IFMFHLEA_01648	6.65e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IFMFHLEA_01649	1.23e-83	-	-	-	S	-	-	-	Protein conserved in bacteria
IFMFHLEA_01650	9.67e-220	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IFMFHLEA_01651	1.91e-171	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IFMFHLEA_01652	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
IFMFHLEA_01653	8.16e-212	-	-	-	EG	-	-	-	EamA-like transporter family
IFMFHLEA_01654	1.03e-211	-	-	-	EG	-	-	-	EamA-like transporter family
IFMFHLEA_01655	1.41e-209	yicL	-	-	EG	-	-	-	EamA-like transporter family
IFMFHLEA_01656	7.08e-137	-	-	-	-	-	-	-	-
IFMFHLEA_01657	6.33e-74	-	-	-	-	-	-	-	-
IFMFHLEA_01658	1.14e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IFMFHLEA_01659	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IFMFHLEA_01660	2.84e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFMFHLEA_01663	1.69e-259	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IFMFHLEA_01664	4.6e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IFMFHLEA_01665	6.65e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
IFMFHLEA_01666	1.23e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IFMFHLEA_01667	6.09e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
IFMFHLEA_01668	1.75e-10	-	-	-	-	-	-	-	-
IFMFHLEA_01669	1.27e-70	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
IFMFHLEA_01670	1e-305	-	-	-	E	-	-	-	amino acid
IFMFHLEA_01671	1.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IFMFHLEA_01672	1.84e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IFMFHLEA_01673	4.27e-293	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IFMFHLEA_01674	8.71e-157	-	-	-	-	-	-	-	-
IFMFHLEA_01675	0.0	-	-	-	L	-	-	-	Transposase
IFMFHLEA_01676	1.07e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMFHLEA_01677	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
IFMFHLEA_01678	4.24e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IFMFHLEA_01679	1e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMFHLEA_01680	8.01e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01681	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01682	5.63e-49	-	-	-	-	-	-	-	-
IFMFHLEA_01683	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IFMFHLEA_01684	9.26e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IFMFHLEA_01685	9.09e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IFMFHLEA_01686	2.86e-81	-	-	-	-	-	-	-	-
IFMFHLEA_01687	3.4e-228	pbpX2	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_01688	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IFMFHLEA_01689	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMFHLEA_01690	3.35e-310	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IFMFHLEA_01691	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMFHLEA_01692	2.17e-25	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IFMFHLEA_01693	2.18e-53	-	-	-	-	-	-	-	-
IFMFHLEA_01694	8.03e-278	-	-	-	S	-	-	-	Membrane
IFMFHLEA_01695	1.97e-107	ykuL	-	-	S	-	-	-	(CBS) domain
IFMFHLEA_01696	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IFMFHLEA_01697	4.69e-262	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IFMFHLEA_01698	2.82e-105	-	-	-	S	-	-	-	Putative adhesin
IFMFHLEA_01699	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IFMFHLEA_01700	1.57e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_01701	5.7e-125	-	-	-	M	-	-	-	CHAP domain
IFMFHLEA_01702	1.4e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_01703	2.41e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMFHLEA_01704	3.39e-253	-	-	-	S	-	-	-	DUF218 domain
IFMFHLEA_01705	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01706	4.51e-134	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IFMFHLEA_01707	1.21e-236	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IFMFHLEA_01708	9.41e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IFMFHLEA_01709	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IFMFHLEA_01710	9.19e-266	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMFHLEA_01711	4.74e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMFHLEA_01712	1.25e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
IFMFHLEA_01713	1.19e-175	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IFMFHLEA_01714	1.63e-152	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IFMFHLEA_01715	6.91e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IFMFHLEA_01716	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IFMFHLEA_01717	3.53e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IFMFHLEA_01718	4.65e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IFMFHLEA_01719	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IFMFHLEA_01720	3.19e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IFMFHLEA_01721	1.9e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IFMFHLEA_01722	6.99e-134	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IFMFHLEA_01723	4.84e-58	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMFHLEA_01724	4.61e-265	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMFHLEA_01725	2.5e-74	-	-	-	-	-	-	-	-
IFMFHLEA_01726	1.62e-211	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IFMFHLEA_01727	9.27e-104	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IFMFHLEA_01728	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IFMFHLEA_01729	4.1e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IFMFHLEA_01730	1.37e-74	-	-	-	-	-	-	-	-
IFMFHLEA_01731	2.09e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IFMFHLEA_01732	3.18e-165	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IFMFHLEA_01733	1.42e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IFMFHLEA_01734	1.33e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IFMFHLEA_01735	5.13e-38	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IFMFHLEA_01736	4.98e-41	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IFMFHLEA_01737	5.94e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IFMFHLEA_01738	1.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IFMFHLEA_01739	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IFMFHLEA_01740	2.03e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IFMFHLEA_01741	3.27e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IFMFHLEA_01742	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IFMFHLEA_01743	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IFMFHLEA_01744	8.26e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IFMFHLEA_01745	9.43e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IFMFHLEA_01746	1.32e-255	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFMFHLEA_01747	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IFMFHLEA_01748	2.41e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IFMFHLEA_01749	1.61e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IFMFHLEA_01750	2.35e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IFMFHLEA_01751	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IFMFHLEA_01752	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IFMFHLEA_01753	2.17e-46	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IFMFHLEA_01754	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IFMFHLEA_01755	2.22e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IFMFHLEA_01756	2.29e-175	-	-	-	S	-	-	-	membrane
IFMFHLEA_01757	1.33e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
IFMFHLEA_01758	4.92e-107	-	-	-	-	-	-	-	-
IFMFHLEA_01759	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMFHLEA_01760	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IFMFHLEA_01761	6.41e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IFMFHLEA_01762	1.24e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IFMFHLEA_01763	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IFMFHLEA_01764	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IFMFHLEA_01765	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IFMFHLEA_01766	1.38e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IFMFHLEA_01767	4.46e-165	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IFMFHLEA_01768	7.2e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IFMFHLEA_01769	9.05e-170	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IFMFHLEA_01770	5.62e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IFMFHLEA_01771	1.49e-138	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IFMFHLEA_01772	8.02e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IFMFHLEA_01773	6.76e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IFMFHLEA_01774	1.29e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IFMFHLEA_01775	2.09e-63	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IFMFHLEA_01776	1.66e-104	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IFMFHLEA_01777	2.65e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IFMFHLEA_01778	5.91e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IFMFHLEA_01779	1.85e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IFMFHLEA_01780	1.69e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IFMFHLEA_01781	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IFMFHLEA_01782	4.56e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IFMFHLEA_01783	2.2e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IFMFHLEA_01784	9.65e-42	-	-	-	K	-	-	-	LysR substrate binding domain
IFMFHLEA_01785	3.73e-65	-	-	-	K	-	-	-	LysR substrate binding domain
IFMFHLEA_01786	4.38e-74	-	-	-	S	-	-	-	FMN_bind
IFMFHLEA_01787	1.87e-292	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IFMFHLEA_01788	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IFMFHLEA_01789	2.5e-51	-	-	-	S	-	-	-	Cytochrome B5
IFMFHLEA_01790	2.27e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IFMFHLEA_01791	1.34e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
IFMFHLEA_01792	1.07e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
IFMFHLEA_01793	6.45e-204	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IFMFHLEA_01794	1.11e-191	-	-	-	I	-	-	-	Acyl-transferase
IFMFHLEA_01795	8.36e-102	-	-	-	-	-	-	-	-
IFMFHLEA_01796	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
IFMFHLEA_01797	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IFMFHLEA_01799	2.21e-129	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IFMFHLEA_01800	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMFHLEA_01801	0.0	yycH	-	-	S	-	-	-	YycH protein
IFMFHLEA_01802	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
IFMFHLEA_01803	9.1e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IFMFHLEA_01804	2.7e-257	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IFMFHLEA_01805	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IFMFHLEA_01806	1.51e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_01808	0.0	-	-	-	S	-	-	-	CAAX protease self-immunity
IFMFHLEA_01809	1.98e-26	-	-	-	-	-	-	-	-
IFMFHLEA_01810	1.09e-157	-	-	-	-	-	-	-	-
IFMFHLEA_01811	8e-226	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IFMFHLEA_01812	6.92e-130	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IFMFHLEA_01813	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01814	2.11e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMFHLEA_01815	9.9e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IFMFHLEA_01816	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IFMFHLEA_01817	4.01e-218	ysdE	-	-	P	-	-	-	Citrate transporter
IFMFHLEA_01818	3.96e-05	ysdE	-	-	P	-	-	-	Citrate transporter
IFMFHLEA_01819	7.83e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IFMFHLEA_01820	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
IFMFHLEA_01821	9.69e-25	-	-	-	-	-	-	-	-
IFMFHLEA_01822	6.75e-127	-	-	-	-	-	-	-	-
IFMFHLEA_01823	4.99e-47	-	-	-	-	-	-	-	-
IFMFHLEA_01825	1.08e-288	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IFMFHLEA_01826	2.11e-271	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IFMFHLEA_01827	1.07e-157	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IFMFHLEA_01828	2.73e-206	-	-	-	L	-	-	-	HNH nucleases
IFMFHLEA_01829	1.63e-233	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
IFMFHLEA_01830	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01831	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IFMFHLEA_01832	3.08e-159	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IFMFHLEA_01833	2.29e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IFMFHLEA_01834	9.33e-180	terC	-	-	P	-	-	-	Integral membrane protein TerC family
IFMFHLEA_01835	2.69e-72	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
IFMFHLEA_01836	2.57e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IFMFHLEA_01837	9.36e-111	-	-	-	-	-	-	-	-
IFMFHLEA_01838	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFMFHLEA_01839	1.45e-231	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IFMFHLEA_01840	1.58e-172	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFMFHLEA_01841	5.06e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IFMFHLEA_01842	2.63e-204	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IFMFHLEA_01843	1.07e-163	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IFMFHLEA_01844	1.02e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMFHLEA_01845	1.33e-75	-	-	-	-	-	-	-	-
IFMFHLEA_01846	4.2e-75	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IFMFHLEA_01847	1.37e-58	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IFMFHLEA_01848	4.08e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IFMFHLEA_01849	3.14e-226	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IFMFHLEA_01850	8.04e-168	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IFMFHLEA_01851	3.51e-209	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IFMFHLEA_01852	8.03e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IFMFHLEA_01853	2.47e-32	-	-	-	-	-	-	-	-
IFMFHLEA_01854	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IFMFHLEA_01855	6.78e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
IFMFHLEA_01856	1.77e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
IFMFHLEA_01857	1.09e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
IFMFHLEA_01858	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IFMFHLEA_01859	2.91e-234	-	-	-	S	-	-	-	DUF218 domain
IFMFHLEA_01860	6.11e-168	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IFMFHLEA_01861	6.65e-153	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IFMFHLEA_01862	1.78e-26	-	-	-	-	-	-	-	-
IFMFHLEA_01863	5.17e-273	-	-	-	-	-	-	-	-
IFMFHLEA_01864	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IFMFHLEA_01865	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IFMFHLEA_01866	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IFMFHLEA_01867	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IFMFHLEA_01868	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IFMFHLEA_01869	2.31e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFMFHLEA_01870	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IFMFHLEA_01871	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IFMFHLEA_01872	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IFMFHLEA_01873	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IFMFHLEA_01874	6.15e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IFMFHLEA_01875	3.1e-269	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IFMFHLEA_01876	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFMFHLEA_01877	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFMFHLEA_01878	9.55e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IFMFHLEA_01879	8.43e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IFMFHLEA_01880	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IFMFHLEA_01881	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IFMFHLEA_01882	6.96e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IFMFHLEA_01883	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IFMFHLEA_01884	1e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
IFMFHLEA_01885	1.96e-225	degV1	-	-	S	-	-	-	DegV family
IFMFHLEA_01886	1.09e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IFMFHLEA_01887	1.38e-33	-	-	-	S	-	-	-	CsbD-like
IFMFHLEA_01888	1.47e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
IFMFHLEA_01889	3.58e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IFMFHLEA_01891	7.47e-133	cadD	-	-	P	-	-	-	Cadmium resistance transporter
IFMFHLEA_01892	2.41e-77	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMFHLEA_01893	2.93e-235	-	-	-	-	-	-	-	-
IFMFHLEA_01894	1.08e-71	-	-	-	-	-	-	-	-
IFMFHLEA_01895	7.23e-264	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IFMFHLEA_01896	4.15e-120	-	-	-	-	-	-	-	-
IFMFHLEA_01897	1.16e-234	-	-	-	EP	-	-	-	Plasmid replication protein
IFMFHLEA_01898	1.45e-42	-	-	-	-	-	-	-	-
IFMFHLEA_01899	4.19e-182	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMFHLEA_01900	3.32e-98	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMFHLEA_01901	4.37e-43	-	-	-	-	-	-	-	-
IFMFHLEA_01902	4.41e-92	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
IFMFHLEA_01903	1.63e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
IFMFHLEA_01906	2.01e-205	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
IFMFHLEA_01907	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IFMFHLEA_01908	5.78e-208	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
IFMFHLEA_01909	4.34e-45	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
IFMFHLEA_01910	1.4e-196	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IFMFHLEA_01911	2.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
IFMFHLEA_01912	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IFMFHLEA_01913	9.95e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IFMFHLEA_01914	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IFMFHLEA_01915	2e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
IFMFHLEA_01916	2.37e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMFHLEA_01917	9.67e-22	-	-	-	-	-	-	-	-
IFMFHLEA_01918	2.79e-313	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IFMFHLEA_01919	6.35e-69	-	-	-	-	-	-	-	-
IFMFHLEA_01920	8.29e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMFHLEA_01921	3.51e-170	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMFHLEA_01922	3.82e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IFMFHLEA_01923	1.29e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IFMFHLEA_01924	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IFMFHLEA_01925	1.15e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IFMFHLEA_01926	9.66e-41	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
IFMFHLEA_01927	1.63e-172	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
IFMFHLEA_01928	8.28e-15	-	-	-	S	-	-	-	interspecies interaction between organisms
IFMFHLEA_01929	5.27e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFMFHLEA_01930	3.08e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IFMFHLEA_01931	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IFMFHLEA_01932	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IFMFHLEA_01933	3.12e-273	pbpX1	-	-	V	-	-	-	Beta-lactamase
IFMFHLEA_01934	6.19e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins