ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NAEKNMFH_00001 4.18e-141 - - - - - - - -
NAEKNMFH_00002 3.03e-243 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NAEKNMFH_00003 7.97e-279 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NAEKNMFH_00004 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NAEKNMFH_00005 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NAEKNMFH_00006 3.27e-38 - - - J - - - Acetyltransferase (GNAT) domain
NAEKNMFH_00007 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NAEKNMFH_00008 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
NAEKNMFH_00009 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NAEKNMFH_00010 2.4e-311 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
NAEKNMFH_00011 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NAEKNMFH_00012 2.73e-206 - - - K - - - Helix-turn-helix domain, rpiR family
NAEKNMFH_00013 2.19e-291 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NAEKNMFH_00014 6.07e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
NAEKNMFH_00016 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NAEKNMFH_00017 5.85e-228 yogA - - C - - - Zinc-binding dehydrogenase
NAEKNMFH_00018 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NAEKNMFH_00019 5.14e-291 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NAEKNMFH_00020 8.27e-96 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NAEKNMFH_00021 5.38e-61 - - - - - - - -
NAEKNMFH_00022 7.52e-197 - - - S - - - TIGRFAM TIGR03943 family protein
NAEKNMFH_00023 1.45e-257 - - - S ko:K07089 - ko00000 Predicted permease
NAEKNMFH_00024 6.34e-33 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
NAEKNMFH_00025 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
NAEKNMFH_00026 1.79e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NAEKNMFH_00027 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAEKNMFH_00028 4.39e-62 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NAEKNMFH_00029 8.64e-177 - - - S - - - cobalamin synthesis protein
NAEKNMFH_00030 5.31e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NAEKNMFH_00031 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
NAEKNMFH_00032 0.0 - - - S - - - Putative esterase
NAEKNMFH_00033 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NAEKNMFH_00034 5.35e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NAEKNMFH_00035 4.93e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NAEKNMFH_00036 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NAEKNMFH_00037 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
NAEKNMFH_00038 9.82e-45 - - - - - - - -
NAEKNMFH_00039 1.64e-90 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NAEKNMFH_00040 4.51e-44 - - - K - - - DNA-binding transcription factor activity
NAEKNMFH_00041 3.66e-187 nnrE - - L - - - Uracil DNA glycosylase superfamily
NAEKNMFH_00042 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
NAEKNMFH_00043 1.08e-146 - - - - - - - -
NAEKNMFH_00044 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
NAEKNMFH_00045 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NAEKNMFH_00046 1.91e-298 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NAEKNMFH_00047 0.0 - - - M - - - Parallel beta-helix repeats
NAEKNMFH_00048 4.41e-291 - - - M - - - Glycosyl transferase 4-like domain
NAEKNMFH_00049 5.42e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
NAEKNMFH_00051 1.16e-80 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NAEKNMFH_00052 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NAEKNMFH_00053 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NAEKNMFH_00054 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NAEKNMFH_00055 0.0 - - - S - - - Esterase-like activity of phytase
NAEKNMFH_00056 7.54e-253 - - - EGP - - - Transmembrane secretion effector
NAEKNMFH_00058 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NAEKNMFH_00059 2.38e-149 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NAEKNMFH_00060 5.95e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NAEKNMFH_00061 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NAEKNMFH_00062 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NAEKNMFH_00063 0.0 - - - S - - - Protein of unknown function DUF262
NAEKNMFH_00064 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_00065 0.0 - - - T - - - Histidine kinase
NAEKNMFH_00066 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
NAEKNMFH_00067 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
NAEKNMFH_00068 1.22e-220 - - - EG - - - EamA-like transporter family
NAEKNMFH_00069 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
NAEKNMFH_00070 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NAEKNMFH_00071 1.31e-235 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NAEKNMFH_00072 4.27e-175 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NAEKNMFH_00073 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
NAEKNMFH_00074 1.29e-159 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NAEKNMFH_00075 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NAEKNMFH_00076 4.91e-104 - - - K - - - Helix-turn-helix XRE-family like proteins
NAEKNMFH_00077 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
NAEKNMFH_00078 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NAEKNMFH_00079 1.46e-146 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NAEKNMFH_00080 9.83e-37 - - - K - - - Winged helix DNA-binding domain
NAEKNMFH_00082 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NAEKNMFH_00083 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAEKNMFH_00085 1.86e-245 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NAEKNMFH_00086 2.64e-141 - - - - - - - -
NAEKNMFH_00087 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NAEKNMFH_00088 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
NAEKNMFH_00089 2.59e-256 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NAEKNMFH_00090 3.28e-156 - - - - - - - -
NAEKNMFH_00091 3.09e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NAEKNMFH_00092 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NAEKNMFH_00093 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NAEKNMFH_00094 1.55e-51 - - - S - - - Protein of unknown function (DUF2975)
NAEKNMFH_00095 1.65e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NAEKNMFH_00096 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
NAEKNMFH_00097 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NAEKNMFH_00098 3.3e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
NAEKNMFH_00099 3.88e-240 - - - S - - - Protein of unknown function (DUF3071)
NAEKNMFH_00100 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
NAEKNMFH_00101 1.23e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NAEKNMFH_00102 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NAEKNMFH_00104 8.48e-88 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
NAEKNMFH_00105 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NAEKNMFH_00106 3.42e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAEKNMFH_00107 6.76e-213 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NAEKNMFH_00108 7.93e-99 - - - P - - - ABC-type metal ion transport system permease component
NAEKNMFH_00109 5.72e-285 - - - S - - - Peptidase dimerisation domain
NAEKNMFH_00110 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NAEKNMFH_00111 4.1e-51 - - - - - - - -
NAEKNMFH_00112 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NAEKNMFH_00113 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAEKNMFH_00114 5.58e-146 - - - S - - - Protein of unknown function (DUF3000)
NAEKNMFH_00115 9.71e-317 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
NAEKNMFH_00116 9.36e-310 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NAEKNMFH_00117 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
NAEKNMFH_00118 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NAEKNMFH_00119 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NAEKNMFH_00120 2.9e-310 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NAEKNMFH_00123 2.12e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
NAEKNMFH_00124 3.37e-290 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NAEKNMFH_00125 1.73e-221 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NAEKNMFH_00126 1.01e-150 safC - - S - - - O-methyltransferase
NAEKNMFH_00127 3.57e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NAEKNMFH_00128 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
NAEKNMFH_00129 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
NAEKNMFH_00130 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
NAEKNMFH_00131 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
NAEKNMFH_00132 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NAEKNMFH_00133 2.83e-201 - - - S - - - Putative ABC-transporter type IV
NAEKNMFH_00134 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
NAEKNMFH_00135 1.53e-215 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_00136 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NAEKNMFH_00137 0.0 - - - I - - - PAP2 superfamily
NAEKNMFH_00138 4.15e-171 - - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_00139 0.0 - - - T - - - Histidine kinase
NAEKNMFH_00140 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
NAEKNMFH_00141 2.58e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NAEKNMFH_00142 2.08e-213 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
NAEKNMFH_00143 5.43e-189 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NAEKNMFH_00144 2.84e-239 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NAEKNMFH_00145 1.1e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NAEKNMFH_00146 2.23e-260 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NAEKNMFH_00147 9.77e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00148 2.11e-291 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NAEKNMFH_00149 7.17e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NAEKNMFH_00150 4.82e-315 - - - K - - - Fic/DOC family
NAEKNMFH_00151 1.92e-162 - - - E - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00152 5.59e-78 yccF - - S - - - Inner membrane component domain
NAEKNMFH_00153 2.48e-198 - - - J - - - Methyltransferase domain
NAEKNMFH_00154 9.93e-100 - - - S - - - Cupin 2, conserved barrel domain protein
NAEKNMFH_00155 0.0 - - - KLT - - - Protein tyrosine kinase
NAEKNMFH_00156 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
NAEKNMFH_00158 1.1e-30 - - - - - - - -
NAEKNMFH_00159 4.68e-265 - - - S - - - Short C-terminal domain
NAEKNMFH_00160 2.37e-117 - - - S - - - Helix-turn-helix
NAEKNMFH_00161 7.03e-86 - - - S - - - Zincin-like metallopeptidase
NAEKNMFH_00162 2.36e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NAEKNMFH_00163 1.59e-48 - - - - - - - -
NAEKNMFH_00164 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NAEKNMFH_00165 2.14e-160 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NAEKNMFH_00166 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
NAEKNMFH_00168 0.0 - - - M - - - Glycosyltransferase like family 2
NAEKNMFH_00169 2.07e-149 - - - E - - - haloacid dehalogenase-like hydrolase
NAEKNMFH_00170 2.58e-186 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NAEKNMFH_00171 6.42e-240 - - - S - - - Conserved hypothetical protein 698
NAEKNMFH_00172 2.04e-79 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NAEKNMFH_00173 6.99e-204 - - - G - - - Phosphoglycerate mutase family
NAEKNMFH_00174 1.12e-303 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
NAEKNMFH_00175 4.89e-105 - - - K - - - AraC-like ligand binding domain
NAEKNMFH_00177 8.2e-68 - - - IQ - - - oxidoreductase activity
NAEKNMFH_00178 2.65e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NAEKNMFH_00179 2.79e-164 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00180 3.19e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAEKNMFH_00181 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NAEKNMFH_00182 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
NAEKNMFH_00183 1.5e-134 - - - - - - - -
NAEKNMFH_00184 5.5e-262 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NAEKNMFH_00185 1.82e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NAEKNMFH_00186 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NAEKNMFH_00187 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
NAEKNMFH_00188 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NAEKNMFH_00189 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NAEKNMFH_00190 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NAEKNMFH_00191 8.68e-229 - - - L - - - Phage integrase family
NAEKNMFH_00192 6.47e-57 - - - V - - - Type I restriction modification DNA specificity domain
NAEKNMFH_00193 4.29e-197 - - - S - - - Domain of unknown function (DUF4357)
NAEKNMFH_00194 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
NAEKNMFH_00195 2.72e-134 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
NAEKNMFH_00196 0.0 - - - K - - - Putative DNA-binding domain
NAEKNMFH_00197 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NAEKNMFH_00198 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NAEKNMFH_00199 9.62e-142 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NAEKNMFH_00200 3.54e-185 - - - S - - - Putative ABC-transporter type IV
NAEKNMFH_00201 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NAEKNMFH_00202 5.64e-280 - - - L - - - Tetratricopeptide repeat
NAEKNMFH_00203 4.37e-242 - - - G - - - Haloacid dehalogenase-like hydrolase
NAEKNMFH_00205 3.26e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NAEKNMFH_00206 4.57e-143 - - - - - - - -
NAEKNMFH_00207 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NAEKNMFH_00208 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
NAEKNMFH_00209 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NAEKNMFH_00210 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NAEKNMFH_00211 8.76e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
NAEKNMFH_00212 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NAEKNMFH_00213 3.01e-225 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00214 6.91e-160 - - - S - - - ABC-2 family transporter protein
NAEKNMFH_00215 3.24e-158 - - - S - - - ABC-2 family transporter protein
NAEKNMFH_00216 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
NAEKNMFH_00217 1.19e-298 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NAEKNMFH_00218 1.27e-120 - - - - - - - -
NAEKNMFH_00219 3.43e-186 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NAEKNMFH_00220 6.24e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAEKNMFH_00222 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NAEKNMFH_00223 6.1e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NAEKNMFH_00224 1.65e-177 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NAEKNMFH_00225 1.26e-100 - - - S - - - Bacterial PH domain
NAEKNMFH_00226 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
NAEKNMFH_00228 8.36e-161 - - - - - - - -
NAEKNMFH_00229 6.92e-171 - - - C - - - Putative TM nitroreductase
NAEKNMFH_00230 1.2e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
NAEKNMFH_00231 3.34e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
NAEKNMFH_00232 1.8e-186 - - - KT - - - RESPONSE REGULATOR receiver
NAEKNMFH_00233 1.12e-246 - - - V - - - VanZ like family
NAEKNMFH_00234 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NAEKNMFH_00235 3.6e-69 - - - S - - - Putative ABC-transporter type IV
NAEKNMFH_00236 1.1e-13 - - - CE ko:K03294 - ko00000 Amino acid permease
NAEKNMFH_00237 1.74e-197 - - - - - - - -
NAEKNMFH_00239 9.04e-126 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NAEKNMFH_00240 3.19e-38 - - - EGP ko:K03446,ko:K03466,ko:K03762,ko:K08217 - br01600,ko00000,ko00002,ko01504,ko02000,ko03036 Major facilitator Superfamily
NAEKNMFH_00241 7.99e-226 - - - M - - - heme binding
NAEKNMFH_00242 1.18e-81 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NAEKNMFH_00244 4.25e-53 - - - - - - - -
NAEKNMFH_00245 2.32e-169 - - - S - - - SOS response associated peptidase (SRAP)
NAEKNMFH_00246 4.97e-99 qseC 2.7.13.3 - T ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Histidine kinase
NAEKNMFH_00247 8.09e-235 - - - S - - - Acetyltransferase (GNAT) domain
NAEKNMFH_00248 1.24e-49 - - - J - - - Aminoacyl-tRNA editing domain
NAEKNMFH_00249 3.96e-28 - - - S - - - Carbon-nitrogen hydrolase
NAEKNMFH_00250 1.08e-46 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
NAEKNMFH_00251 3.41e-72 - - - K - - - Transcriptional regulator
NAEKNMFH_00252 1.55e-116 - - - K - - - FR47-like protein
NAEKNMFH_00253 7.51e-152 - - - J - - - Acetyltransferase (GNAT) domain
NAEKNMFH_00254 8.22e-85 - - - K - - - Protein of unknown function, DUF488
NAEKNMFH_00255 7.28e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NAEKNMFH_00256 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00257 7.67e-188 - - - S - - - Domain of unknown function (DUF4194)
NAEKNMFH_00258 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00259 0.0 - - - E - - - Serine carboxypeptidase
NAEKNMFH_00260 4.05e-207 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NAEKNMFH_00261 1.42e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NAEKNMFH_00262 6.21e-213 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NAEKNMFH_00263 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NAEKNMFH_00264 3.26e-166 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
NAEKNMFH_00265 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
NAEKNMFH_00266 1.05e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NAEKNMFH_00267 7.36e-152 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
NAEKNMFH_00268 1.71e-204 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
NAEKNMFH_00269 9.98e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
NAEKNMFH_00270 1.13e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NAEKNMFH_00272 1.34e-167 - - - M - - - Peptidase family M23
NAEKNMFH_00273 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NAEKNMFH_00274 0.0 - - - G - - - ABC transporter substrate-binding protein
NAEKNMFH_00275 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
NAEKNMFH_00276 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
NAEKNMFH_00277 5.1e-118 - - - - - - - -
NAEKNMFH_00278 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
NAEKNMFH_00279 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NAEKNMFH_00280 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NAEKNMFH_00281 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NAEKNMFH_00282 2.6e-163 - - - S - - - alpha beta
NAEKNMFH_00283 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NAEKNMFH_00284 7.62e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NAEKNMFH_00285 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
NAEKNMFH_00286 2.19e-291 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NAEKNMFH_00287 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NAEKNMFH_00288 2.68e-96 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NAEKNMFH_00289 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NAEKNMFH_00290 1.1e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NAEKNMFH_00291 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00292 1.93e-215 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NAEKNMFH_00293 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
NAEKNMFH_00294 4.48e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NAEKNMFH_00295 1.28e-277 - - - GK - - - ROK family
NAEKNMFH_00296 4.9e-264 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
NAEKNMFH_00297 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NAEKNMFH_00298 4.81e-253 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NAEKNMFH_00299 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
NAEKNMFH_00300 1.31e-178 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NAEKNMFH_00301 0.0 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NAEKNMFH_00302 2.13e-151 - - - K - - - Transcriptional regulatory protein, C terminal
NAEKNMFH_00303 9.29e-79 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NAEKNMFH_00304 3.92e-118 - - - - - - - -
NAEKNMFH_00305 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NAEKNMFH_00306 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NAEKNMFH_00307 2.05e-228 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
NAEKNMFH_00308 3.02e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NAEKNMFH_00309 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NAEKNMFH_00310 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
NAEKNMFH_00311 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAEKNMFH_00312 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
NAEKNMFH_00313 1.23e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NAEKNMFH_00314 2.01e-207 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NAEKNMFH_00315 1.22e-307 - - - V - - - MatE
NAEKNMFH_00318 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NAEKNMFH_00319 1.27e-181 - - - S - - - Protein of unknown function (DUF1275)
NAEKNMFH_00320 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NAEKNMFH_00321 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
NAEKNMFH_00322 3.75e-285 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NAEKNMFH_00323 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NAEKNMFH_00324 1.93e-202 - - - G - - - Fructosamine kinase
NAEKNMFH_00325 2.34e-215 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NAEKNMFH_00326 8.28e-199 - - - S - - - PAC2 family
NAEKNMFH_00330 5.26e-141 - - - - - - - -
NAEKNMFH_00331 5.7e-87 - - - - - - - -
NAEKNMFH_00335 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NAEKNMFH_00336 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NAEKNMFH_00337 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NAEKNMFH_00338 2.79e-176 yebC - - K - - - transcriptional regulatory protein
NAEKNMFH_00339 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NAEKNMFH_00341 2.6e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NAEKNMFH_00342 6.91e-259 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NAEKNMFH_00343 3.73e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
NAEKNMFH_00344 1.12e-130 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NAEKNMFH_00345 8.17e-285 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NAEKNMFH_00346 3.88e-211 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NAEKNMFH_00347 1.35e-314 - - - - - - - -
NAEKNMFH_00348 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NAEKNMFH_00349 5.17e-56 - - - - - - - -
NAEKNMFH_00350 9.95e-160 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NAEKNMFH_00351 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NAEKNMFH_00352 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NAEKNMFH_00353 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NAEKNMFH_00354 8.46e-206 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NAEKNMFH_00355 1.79e-243 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NAEKNMFH_00356 4.24e-142 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
NAEKNMFH_00357 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
NAEKNMFH_00358 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
NAEKNMFH_00359 1.83e-150 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NAEKNMFH_00360 4.59e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
NAEKNMFH_00361 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
NAEKNMFH_00362 3.22e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
NAEKNMFH_00363 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NAEKNMFH_00364 9.35e-152 merR2 - - K - - - helix_turn_helix, mercury resistance
NAEKNMFH_00365 1.35e-80 - - - - - - - -
NAEKNMFH_00367 4.15e-120 - - - L - - - DNA integration
NAEKNMFH_00368 1.07e-162 - - - S - - - GyrI-like small molecule binding domain
NAEKNMFH_00369 1.49e-117 - - - K - - - Putative zinc ribbon domain
NAEKNMFH_00372 5.93e-183 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
NAEKNMFH_00373 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NAEKNMFH_00374 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
NAEKNMFH_00375 3.7e-70 - - - - - - - -
NAEKNMFH_00376 0.0 - - - K - - - WYL domain
NAEKNMFH_00377 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NAEKNMFH_00379 1.24e-87 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
NAEKNMFH_00380 7.48e-186 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NAEKNMFH_00381 1.09e-06 sdh - - S - - - Enoyl-(Acyl carrier protein) reductase
NAEKNMFH_00382 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NAEKNMFH_00383 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NAEKNMFH_00384 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NAEKNMFH_00385 2.27e-119 - - - T - - - Domain of unknown function (DUF4234)
NAEKNMFH_00386 1.66e-131 - - - K - - - Bacterial regulatory proteins, tetR family
NAEKNMFH_00387 2.54e-24 - - - - - - - -
NAEKNMFH_00388 4.89e-63 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
NAEKNMFH_00389 1.17e-54 - - - K - - - Helix-turn-helix
NAEKNMFH_00390 2.42e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
NAEKNMFH_00391 5.34e-90 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
NAEKNMFH_00392 1.13e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
NAEKNMFH_00393 5.92e-119 - - - K - - - Transcriptional regulator PadR-like family
NAEKNMFH_00394 2.21e-171 - - - L ko:K07457 - ko00000 endonuclease III
NAEKNMFH_00395 1.39e-168 - - - S - - - Enoyl-(Acyl carrier protein) reductase
NAEKNMFH_00396 3.81e-309 - - - V - - - MatE
NAEKNMFH_00397 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NAEKNMFH_00398 1.36e-19 - - - KLT - - - Protein tyrosine kinase
NAEKNMFH_00399 2.8e-207 - - - - - - - -
NAEKNMFH_00400 7.02e-245 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NAEKNMFH_00401 2.05e-98 - - - K - - - MerR family regulatory protein
NAEKNMFH_00402 5.01e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NAEKNMFH_00403 1.67e-228 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NAEKNMFH_00404 2.71e-195 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NAEKNMFH_00405 3.99e-231 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
NAEKNMFH_00406 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NAEKNMFH_00407 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NAEKNMFH_00408 7.76e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NAEKNMFH_00409 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NAEKNMFH_00411 8.19e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NAEKNMFH_00412 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NAEKNMFH_00413 5.84e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
NAEKNMFH_00414 1.65e-264 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NAEKNMFH_00415 1.09e-225 - - - I - - - alpha/beta hydrolase fold
NAEKNMFH_00416 1.17e-34 - - - S - - - Rard protein
NAEKNMFH_00417 1.34e-119 - - - E - - - Rard protein
NAEKNMFH_00418 7.96e-41 - - - - - - - -
NAEKNMFH_00419 7.9e-35 - - - S - - - Protein of unknown function DUF262
NAEKNMFH_00420 1.48e-102 - - - K - - - Psort location Cytoplasmic, score
NAEKNMFH_00421 1.64e-282 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator superfamily
NAEKNMFH_00422 0.0 - - - S - - - Protein of unknown function DUF262
NAEKNMFH_00423 3.33e-316 - - - S ko:K06915 - ko00000 AAA-like domain
NAEKNMFH_00424 1.57e-67 - - - S - - - SIR2-like domain
NAEKNMFH_00425 6.12e-233 - - - V - - - Type III restriction enzyme res subunit
NAEKNMFH_00426 5.13e-202 - - - L - - - Eco57I restriction-modification methylase
NAEKNMFH_00427 0.0 - - - KL - - - Type III restriction enzyme res subunit
NAEKNMFH_00428 1.09e-168 - - - - - - - -
NAEKNMFH_00429 3.12e-212 - - - L ko:K07485 - ko00000 Transposase
NAEKNMFH_00430 9.96e-52 - - - L - - - Helix-turn-helix domain
NAEKNMFH_00431 1.58e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NAEKNMFH_00432 5.84e-141 - - - S ko:K07126 - ko00000 Sel1-like repeats.
NAEKNMFH_00433 6.28e-176 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
NAEKNMFH_00434 8.1e-232 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00435 5.82e-313 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
NAEKNMFH_00436 5.23e-107 - - - - - - - -
NAEKNMFH_00437 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NAEKNMFH_00438 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
NAEKNMFH_00439 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
NAEKNMFH_00440 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
NAEKNMFH_00441 4.49e-310 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NAEKNMFH_00442 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NAEKNMFH_00443 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NAEKNMFH_00444 4.63e-175 - - - S - - - UPF0126 domain
NAEKNMFH_00445 2.41e-143 - - - T - - - RNA ligase
NAEKNMFH_00446 7.49e-286 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
NAEKNMFH_00447 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NAEKNMFH_00448 2.09e-242 - - - S ko:K06889 - ko00000 alpha beta
NAEKNMFH_00449 1.16e-304 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NAEKNMFH_00450 3.63e-57 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
NAEKNMFH_00451 6.9e-259 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
NAEKNMFH_00452 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NAEKNMFH_00453 1.45e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NAEKNMFH_00454 0.0 corC - - S - - - CBS domain
NAEKNMFH_00455 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NAEKNMFH_00456 1.05e-253 phoH - - T ko:K06217 - ko00000 PhoH-like protein
NAEKNMFH_00457 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NAEKNMFH_00458 2.09e-173 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NAEKNMFH_00460 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
NAEKNMFH_00461 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NAEKNMFH_00462 1.17e-137 - - - S - - - Iron-sulfur cluster assembly protein
NAEKNMFH_00463 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NAEKNMFH_00464 3.62e-306 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NAEKNMFH_00465 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NAEKNMFH_00466 2.92e-298 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
NAEKNMFH_00467 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
NAEKNMFH_00468 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NAEKNMFH_00469 1.31e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
NAEKNMFH_00470 2e-153 - - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_00471 1.12e-130 - - - - - - - -
NAEKNMFH_00472 2.27e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NAEKNMFH_00473 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NAEKNMFH_00474 1.57e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NAEKNMFH_00475 4.83e-65 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
NAEKNMFH_00476 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NAEKNMFH_00477 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NAEKNMFH_00478 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NAEKNMFH_00479 7.33e-50 - - - - - - - -
NAEKNMFH_00480 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
NAEKNMFH_00481 1.78e-172 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NAEKNMFH_00482 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
NAEKNMFH_00483 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NAEKNMFH_00484 6.67e-173 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NAEKNMFH_00485 4.6e-272 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NAEKNMFH_00486 1e-83 - - - S - - - Domain of unknown function (DUF4418)
NAEKNMFH_00487 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NAEKNMFH_00488 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
NAEKNMFH_00489 6.52e-139 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NAEKNMFH_00490 1.67e-307 pbuX - - F ko:K03458 - ko00000 Permease family
NAEKNMFH_00492 1.25e-54 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NAEKNMFH_00493 2.02e-141 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NAEKNMFH_00495 4.2e-145 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
NAEKNMFH_00496 1.65e-36 - - - - - - - -
NAEKNMFH_00497 3.3e-49 - - - H - - - Adenine-specific methyltransferase EcoRI
NAEKNMFH_00498 1.57e-69 - - - H - - - Adenine-specific methyltransferase EcoRI
NAEKNMFH_00499 1.28e-18 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NAEKNMFH_00500 2.3e-75 - - - L - - - Transposase
NAEKNMFH_00501 1.08e-26 - - - L - - - transposase, IS605 OrfB family
NAEKNMFH_00502 3.72e-55 higA - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix
NAEKNMFH_00503 1.75e-50 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
NAEKNMFH_00505 1e-109 - - - - - - - -
NAEKNMFH_00507 5.6e-115 - - - L - - - Transposase and inactivated derivatives IS30 family
NAEKNMFH_00508 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NAEKNMFH_00509 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NAEKNMFH_00510 1.32e-288 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NAEKNMFH_00511 7.22e-237 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00512 3.23e-25 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
NAEKNMFH_00513 1.45e-298 - - - T - - - Histidine kinase
NAEKNMFH_00514 2.29e-155 - - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_00515 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
NAEKNMFH_00516 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
NAEKNMFH_00517 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NAEKNMFH_00518 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NAEKNMFH_00520 2.71e-101 - - - - - - - -
NAEKNMFH_00521 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
NAEKNMFH_00522 9.36e-295 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NAEKNMFH_00523 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NAEKNMFH_00524 9.85e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
NAEKNMFH_00525 4.61e-31 - - - L - - - Phage integrase family
NAEKNMFH_00526 1.41e-88 - - - L - - - Phage integrase family
NAEKNMFH_00528 5.3e-283 - - - - - - - -
NAEKNMFH_00529 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NAEKNMFH_00530 1.7e-157 - - - L - - - NUDIX domain
NAEKNMFH_00531 3.64e-219 - - - L - - - NIF3 (NGG1p interacting factor 3)
NAEKNMFH_00532 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NAEKNMFH_00533 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
NAEKNMFH_00535 8.13e-141 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NAEKNMFH_00536 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
NAEKNMFH_00537 3.96e-228 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
NAEKNMFH_00538 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NAEKNMFH_00539 2.24e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NAEKNMFH_00540 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NAEKNMFH_00541 2.44e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NAEKNMFH_00542 6.88e-231 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NAEKNMFH_00543 2.83e-210 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00544 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
NAEKNMFH_00545 8.94e-109 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NAEKNMFH_00546 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
NAEKNMFH_00547 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NAEKNMFH_00548 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
NAEKNMFH_00549 8.4e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NAEKNMFH_00550 1.85e-92 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
NAEKNMFH_00551 1.62e-168 pyrE_1 - - S - - - Phosphoribosyl transferase domain
NAEKNMFH_00552 3.31e-200 - - - T - - - Eukaryotic phosphomannomutase
NAEKNMFH_00553 1.05e-85 - - - S - - - Zincin-like metallopeptidase
NAEKNMFH_00554 0.0 - - - - - - - -
NAEKNMFH_00555 0.0 - - - S - - - Glycosyl transferase, family 2
NAEKNMFH_00556 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NAEKNMFH_00557 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
NAEKNMFH_00558 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
NAEKNMFH_00559 1.92e-60 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NAEKNMFH_00560 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NAEKNMFH_00561 2.77e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NAEKNMFH_00563 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NAEKNMFH_00564 3.48e-94 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
NAEKNMFH_00565 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
NAEKNMFH_00566 7.29e-125 - - - - - - - -
NAEKNMFH_00568 5.06e-235 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NAEKNMFH_00569 6.25e-138 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
NAEKNMFH_00570 1.2e-130 - - - D - - - Septum formation initiator
NAEKNMFH_00571 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NAEKNMFH_00572 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
NAEKNMFH_00573 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
NAEKNMFH_00574 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NAEKNMFH_00575 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NAEKNMFH_00576 9.1e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NAEKNMFH_00577 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NAEKNMFH_00578 1.2e-194 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NAEKNMFH_00579 2.01e-251 - - - GM - - - GDP-mannose 4,6 dehydratase
NAEKNMFH_00580 3.01e-164 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NAEKNMFH_00583 2.06e-280 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
NAEKNMFH_00584 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NAEKNMFH_00585 2.04e-263 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NAEKNMFH_00586 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
NAEKNMFH_00587 6.94e-298 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
NAEKNMFH_00588 1.68e-254 - - - - - - - -
NAEKNMFH_00589 1.7e-194 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00590 6.47e-246 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
NAEKNMFH_00591 0.0 argE - - E - - - Peptidase dimerisation domain
NAEKNMFH_00592 2.07e-134 - - - S - - - Protein of unknown function (DUF3043)
NAEKNMFH_00593 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAEKNMFH_00594 5.21e-183 - - - S - - - Domain of unknown function (DUF4191)
NAEKNMFH_00595 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NAEKNMFH_00598 1.5e-15 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
NAEKNMFH_00602 1.9e-98 - - - S - - - GIY-YIG catalytic domain
NAEKNMFH_00603 2.5e-39 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
NAEKNMFH_00604 1.9e-137 - - - L - - - Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NAEKNMFH_00605 2.9e-105 - - - L - - - Phage integrase, N-terminal SAM-like domain
NAEKNMFH_00606 1.73e-204 - - - S - - - Protein conserved in bacteria
NAEKNMFH_00607 2.36e-269 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NAEKNMFH_00608 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NAEKNMFH_00609 0.0 - - - S - - - Tetratricopeptide repeat
NAEKNMFH_00610 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NAEKNMFH_00611 2.32e-99 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NAEKNMFH_00612 1.04e-176 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_00613 3.37e-270 - - - E - - - Aminotransferase class I and II
NAEKNMFH_00614 5.43e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NAEKNMFH_00615 3.41e-136 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NAEKNMFH_00616 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_00617 0.0 - - - EGP - - - Major Facilitator Superfamily
NAEKNMFH_00619 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
NAEKNMFH_00620 0.0 - - - L - - - DEAD DEAH box helicase
NAEKNMFH_00621 2.49e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
NAEKNMFH_00622 6.57e-253 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00623 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00624 5.91e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NAEKNMFH_00625 2.08e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
NAEKNMFH_00626 1.59e-120 - - - S - - - Aminoacyl-tRNA editing domain
NAEKNMFH_00627 1.2e-98 - - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_00628 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NAEKNMFH_00629 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
NAEKNMFH_00630 5.86e-299 - - - S - - - Domain of Unknown Function (DUF349)
NAEKNMFH_00631 9.32e-14 - 2.7.13.3 - T ko:K07675,ko:K20263 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NAEKNMFH_00634 5.19e-204 - - - L - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00635 2.74e-165 - - - L - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00636 4.79e-34 - - - S - - - Transposon-encoded protein TnpW
NAEKNMFH_00637 3.47e-209 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA-dependent DNA replication
NAEKNMFH_00638 2.03e-189 rpiA 5.3.1.6 - K ko:K01807,ko:K02444 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko03000 DNA-binding transcription factor activity
NAEKNMFH_00639 1.19e-89 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00640 0.0 - - - D - - - COG COG3843 Type IV secretory pathway, VirD2 components (relaxase)
NAEKNMFH_00641 1.22e-84 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_00642 1.47e-45 - - - S - - - Helix-turn-helix domain
NAEKNMFH_00643 4.57e-60 - - - K - - - sigma factor activity
NAEKNMFH_00644 1.72e-21 - - - K - - - sigma factor activity
NAEKNMFH_00645 9.79e-183 - - - Q - - - Psort location Cytoplasmic, score
NAEKNMFH_00646 7.28e-207 - - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
NAEKNMFH_00647 3.15e-162 - - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
NAEKNMFH_00648 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
NAEKNMFH_00649 2.42e-237 uspA - - T - - - Belongs to the universal stress protein A family
NAEKNMFH_00650 1.05e-251 - - - S - - - Protein of unknown function (DUF3027)
NAEKNMFH_00651 7.13e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NAEKNMFH_00652 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NAEKNMFH_00653 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
NAEKNMFH_00654 2.69e-229 - - - - - - - -
NAEKNMFH_00655 3.36e-52 - - - S - - - Proteins of 100 residues with WXG
NAEKNMFH_00656 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NAEKNMFH_00657 1.01e-56 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NAEKNMFH_00658 3.46e-104 - - - S - - - LytR cell envelope-related transcriptional attenuator
NAEKNMFH_00659 7.48e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NAEKNMFH_00660 1.22e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NAEKNMFH_00661 1.49e-227 - - - S - - - Protein of unknown function DUF58
NAEKNMFH_00662 1.78e-121 - - - - - - - -
NAEKNMFH_00663 7.9e-247 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NAEKNMFH_00664 9.48e-197 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NAEKNMFH_00665 2.27e-117 - - - - - - - -
NAEKNMFH_00667 0.0 - - - S - - - PGAP1-like protein
NAEKNMFH_00668 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
NAEKNMFH_00669 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
NAEKNMFH_00670 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
NAEKNMFH_00671 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NAEKNMFH_00672 3.51e-27 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NAEKNMFH_00673 3.29e-202 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
NAEKNMFH_00674 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
NAEKNMFH_00675 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
NAEKNMFH_00676 2.25e-178 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
NAEKNMFH_00677 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NAEKNMFH_00678 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NAEKNMFH_00679 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NAEKNMFH_00680 7.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NAEKNMFH_00681 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NAEKNMFH_00682 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
NAEKNMFH_00683 9.33e-223 - - - S - - - Protein conserved in bacteria
NAEKNMFH_00685 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NAEKNMFH_00686 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NAEKNMFH_00687 2.99e-142 - - - - - - - -
NAEKNMFH_00688 7.55e-313 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAEKNMFH_00689 1.87e-172 - - - S - - - Protein of unknown function (DUF3159)
NAEKNMFH_00690 2.66e-196 - - - S - - - Protein of unknown function (DUF3710)
NAEKNMFH_00691 3.49e-216 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
NAEKNMFH_00692 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NAEKNMFH_00693 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NAEKNMFH_00694 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NAEKNMFH_00695 5.29e-212 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
NAEKNMFH_00696 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00697 5.3e-233 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NAEKNMFH_00698 7.67e-56 - - - - - - - -
NAEKNMFH_00699 1.48e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
NAEKNMFH_00700 3.39e-252 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NAEKNMFH_00701 6.4e-110 - - - - - - - -
NAEKNMFH_00702 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
NAEKNMFH_00703 1.52e-299 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
NAEKNMFH_00704 5.53e-210 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
NAEKNMFH_00705 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NAEKNMFH_00706 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NAEKNMFH_00707 6.18e-198 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
NAEKNMFH_00708 2.12e-124 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NAEKNMFH_00709 8.34e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NAEKNMFH_00710 1.31e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NAEKNMFH_00711 9.73e-228 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
NAEKNMFH_00712 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NAEKNMFH_00713 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
NAEKNMFH_00714 6.89e-134 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NAEKNMFH_00715 9.12e-10 - - - S - - - Spermine/spermidine synthase domain
NAEKNMFH_00716 1.39e-171 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
NAEKNMFH_00717 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NAEKNMFH_00718 1.49e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NAEKNMFH_00719 3.63e-228 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NAEKNMFH_00720 6.49e-249 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NAEKNMFH_00721 3.35e-84 - - - - - - - -
NAEKNMFH_00722 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NAEKNMFH_00723 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NAEKNMFH_00724 1.26e-244 - - - V - - - Acetyltransferase (GNAT) domain
NAEKNMFH_00725 7.95e-292 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
NAEKNMFH_00726 6.99e-307 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
NAEKNMFH_00727 1.46e-165 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NAEKNMFH_00728 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NAEKNMFH_00729 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
NAEKNMFH_00731 2.16e-125 - - - F - - - NUDIX domain
NAEKNMFH_00732 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
NAEKNMFH_00733 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NAEKNMFH_00734 3.74e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00735 5.3e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_00736 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NAEKNMFH_00737 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NAEKNMFH_00738 4.88e-195 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NAEKNMFH_00739 4.81e-275 - - - GK - - - ROK family
NAEKNMFH_00740 1.67e-169 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NAEKNMFH_00741 5.33e-286 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NAEKNMFH_00742 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NAEKNMFH_00743 6.45e-302 - - - G - - - Major Facilitator Superfamily
NAEKNMFH_00744 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NAEKNMFH_00747 4.8e-231 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
NAEKNMFH_00748 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NAEKNMFH_00749 4.28e-274 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NAEKNMFH_00750 6.73e-258 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
NAEKNMFH_00751 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NAEKNMFH_00752 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NAEKNMFH_00753 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NAEKNMFH_00754 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NAEKNMFH_00755 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
NAEKNMFH_00756 5.63e-97 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NAEKNMFH_00757 2.17e-246 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NAEKNMFH_00758 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NAEKNMFH_00759 0.0 - - - L - - - DNA helicase
NAEKNMFH_00760 3.23e-290 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NAEKNMFH_00761 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NAEKNMFH_00762 2.4e-65 - - - M - - - Lysin motif
NAEKNMFH_00763 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NAEKNMFH_00764 7.5e-211 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NAEKNMFH_00765 1.13e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NAEKNMFH_00766 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NAEKNMFH_00767 7.35e-221 - - - - - - - -
NAEKNMFH_00768 1.7e-155 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
NAEKNMFH_00769 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
NAEKNMFH_00770 9.89e-241 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NAEKNMFH_00771 2.91e-173 - - - S - - - Domain of unknown function (DUF5067)
NAEKNMFH_00772 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NAEKNMFH_00773 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
NAEKNMFH_00774 8.32e-168 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
NAEKNMFH_00775 3.31e-157 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NAEKNMFH_00776 1.84e-151 - - - - - - - -
NAEKNMFH_00777 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
NAEKNMFH_00778 2.16e-284 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NAEKNMFH_00779 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NAEKNMFH_00780 1.09e-231 - - - S - - - Protein conserved in bacteria
NAEKNMFH_00783 4.15e-98 - - - S - - - Domain of unknown function (DUF4186)
NAEKNMFH_00784 5.19e-222 dkgV - - C - - - Aldo/keto reductase family
NAEKNMFH_00785 6.87e-47 - - - S - - - Aldo/keto reductase family
NAEKNMFH_00786 1.15e-121 - - - S - - - Aldo/keto reductase family
NAEKNMFH_00787 1.69e-256 - - - K - - - WYL domain
NAEKNMFH_00789 0.000563 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NAEKNMFH_00790 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
NAEKNMFH_00791 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
NAEKNMFH_00792 1.48e-146 - - - S - - - zinc-ribbon domain
NAEKNMFH_00793 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
NAEKNMFH_00794 1.11e-53 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NAEKNMFH_00795 1.32e-23 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NAEKNMFH_00796 1.59e-243 - - - S - - - Domain of unknown function (DUF1963)
NAEKNMFH_00797 2.53e-198 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NAEKNMFH_00798 2.49e-183 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NAEKNMFH_00799 0.0 - - - I - - - acetylesterase activity
NAEKNMFH_00800 9.79e-299 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NAEKNMFH_00801 8.77e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NAEKNMFH_00802 1.58e-303 - - - NU - - - Tfp pilus assembly protein FimV
NAEKNMFH_00804 3.79e-16 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_00805 9.38e-13 - - - - - - - -
NAEKNMFH_00806 3.75e-116 - - - - - - - -
NAEKNMFH_00807 2.72e-188 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
NAEKNMFH_00808 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NAEKNMFH_00809 3.55e-283 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
NAEKNMFH_00810 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
NAEKNMFH_00811 1.93e-304 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
NAEKNMFH_00812 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NAEKNMFH_00813 2.62e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NAEKNMFH_00814 1.25e-82 - - - - - - - -
NAEKNMFH_00816 7.68e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NAEKNMFH_00817 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NAEKNMFH_00818 1.65e-191 - - - V - - - DivIVA protein
NAEKNMFH_00819 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
NAEKNMFH_00820 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NAEKNMFH_00821 5.42e-293 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NAEKNMFH_00822 8.15e-315 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NAEKNMFH_00823 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
NAEKNMFH_00824 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
NAEKNMFH_00825 7.14e-202 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NAEKNMFH_00826 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NAEKNMFH_00827 1.62e-110 - - - - - - - -
NAEKNMFH_00828 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
NAEKNMFH_00829 1.71e-209 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NAEKNMFH_00830 1.52e-81 - - - S - - - Thiamine-binding protein
NAEKNMFH_00831 2.78e-248 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_00833 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
NAEKNMFH_00834 4.62e-190 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NAEKNMFH_00835 0.0 - - - S - - - Zincin-like metallopeptidase
NAEKNMFH_00836 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NAEKNMFH_00837 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
NAEKNMFH_00838 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
NAEKNMFH_00839 2.97e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
NAEKNMFH_00840 2.91e-148 - - - S - - - Vitamin K epoxide reductase
NAEKNMFH_00841 7.32e-216 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NAEKNMFH_00842 2.24e-195 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NAEKNMFH_00843 2.16e-218 - - - S - - - Patatin-like phospholipase
NAEKNMFH_00844 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NAEKNMFH_00845 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_00846 5.82e-114 - - - K - - - MarR family
NAEKNMFH_00848 0.0 - - - M - - - Parallel beta-helix repeats
NAEKNMFH_00849 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
NAEKNMFH_00850 3.9e-213 - - - - - - - -
NAEKNMFH_00851 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
NAEKNMFH_00853 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAEKNMFH_00854 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
NAEKNMFH_00855 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAEKNMFH_00856 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAEKNMFH_00857 4.32e-258 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
NAEKNMFH_00859 6.61e-06 - - - K - - - Bacterial regulatory proteins, lacI family
NAEKNMFH_00860 1.65e-234 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NAEKNMFH_00861 0.0 - - - OP - - - Sulfurtransferase TusA
NAEKNMFH_00862 8.74e-193 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
NAEKNMFH_00863 2.78e-170 tmp1 - - S - - - Domain of unknown function (DUF4391)
NAEKNMFH_00864 2.21e-47 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NAEKNMFH_00865 1.27e-291 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
NAEKNMFH_00866 1.95e-140 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NAEKNMFH_00867 0.0 - - - S - - - zinc finger
NAEKNMFH_00868 6.43e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NAEKNMFH_00869 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NAEKNMFH_00870 0.0 vpr - - O - - - Subtilase family
NAEKNMFH_00871 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
NAEKNMFH_00872 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAEKNMFH_00873 6.97e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NAEKNMFH_00874 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NAEKNMFH_00875 3e-47 - - - L - - - Transposase
NAEKNMFH_00876 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NAEKNMFH_00877 8.15e-23 - - - P ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NAEKNMFH_00878 2.64e-316 - - - G - - - Major Facilitator Superfamily
NAEKNMFH_00879 6.85e-195 - - - K - - - -acetyltransferase
NAEKNMFH_00880 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
NAEKNMFH_00881 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
NAEKNMFH_00882 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NAEKNMFH_00883 0.0 - - - S - - - Fibronectin type 3 domain
NAEKNMFH_00884 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NAEKNMFH_00885 9.84e-297 - - - S - - - Protein of unknown function DUF58
NAEKNMFH_00886 0.0 - - - E - - - Transglutaminase-like superfamily
NAEKNMFH_00887 4.74e-211 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
NAEKNMFH_00888 5.39e-99 - - - B - - - Belongs to the OprB family
NAEKNMFH_00889 6.53e-125 - - - T - - - Forkhead associated domain
NAEKNMFH_00890 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAEKNMFH_00891 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAEKNMFH_00892 2.96e-139 - - - - - - - -
NAEKNMFH_00893 3.15e-236 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
NAEKNMFH_00894 2.16e-42 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
NAEKNMFH_00895 1.25e-75 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
NAEKNMFH_00896 5.27e-156 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NAEKNMFH_00897 4.1e-237 - - - S - - - Membrane
NAEKNMFH_00898 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
NAEKNMFH_00899 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NAEKNMFH_00900 1.32e-308 - - - EGP - - - Sugar (and other) transporter
NAEKNMFH_00901 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
NAEKNMFH_00902 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
NAEKNMFH_00903 1.2e-179 - - - K - - - DeoR C terminal sensor domain
NAEKNMFH_00904 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NAEKNMFH_00905 1.5e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
NAEKNMFH_00906 0.0 pon1 - - M - - - Transglycosylase
NAEKNMFH_00907 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NAEKNMFH_00908 7.33e-150 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
NAEKNMFH_00909 2.36e-71 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
NAEKNMFH_00910 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NAEKNMFH_00911 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
NAEKNMFH_00912 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
NAEKNMFH_00913 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NAEKNMFH_00914 0.0 - - - S - - - L,D-transpeptidase catalytic domain
NAEKNMFH_00916 6.95e-204 - - - I - - - Alpha/beta hydrolase family
NAEKNMFH_00917 3.88e-152 - - - F - - - Domain of unknown function (DUF4916)
NAEKNMFH_00918 8.62e-77 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
NAEKNMFH_00919 3.53e-230 - - - S ko:K21688 - ko00000 G5
NAEKNMFH_00920 0.0 - - - - - - - -
NAEKNMFH_00921 6.25e-131 - - - L ko:K07483 - ko00000 Integrase core domain
NAEKNMFH_00923 1.33e-105 - - - K - - - Winged helix DNA-binding domain
NAEKNMFH_00924 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_00925 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NAEKNMFH_00926 2.89e-96 - - - - - - - -
NAEKNMFH_00927 1.4e-89 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NAEKNMFH_00928 1.03e-24 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NAEKNMFH_00929 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NAEKNMFH_00930 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
NAEKNMFH_00931 6.85e-255 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
NAEKNMFH_00932 7.87e-171 icaR - - K - - - Bacterial regulatory proteins, tetR family
NAEKNMFH_00934 4.3e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NAEKNMFH_00935 2.1e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
NAEKNMFH_00936 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
NAEKNMFH_00937 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
NAEKNMFH_00938 0.0 dinF - - V - - - MatE
NAEKNMFH_00939 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NAEKNMFH_00940 0.0 murE - - M - - - Domain of unknown function (DUF1727)
NAEKNMFH_00941 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
NAEKNMFH_00942 3.15e-44 - - - S - - - granule-associated protein
NAEKNMFH_00943 0.0 - - - S ko:K03688 - ko00000 ABC1 family
NAEKNMFH_00944 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NAEKNMFH_00945 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
NAEKNMFH_00946 1.45e-297 rmuC - - S ko:K09760 - ko00000 RmuC family
NAEKNMFH_00947 7.09e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NAEKNMFH_00948 5.56e-213 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
NAEKNMFH_00949 3.01e-79 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NAEKNMFH_00950 7.55e-77 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NAEKNMFH_00952 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAEKNMFH_00953 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NAEKNMFH_00954 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAEKNMFH_00955 1.38e-251 - - - J - - - Acetyltransferase (GNAT) domain
NAEKNMFH_00956 1.32e-68 - - - S - - - Protein of unknown function (DUF2469)
NAEKNMFH_00957 0.0 - - - H - - - Flavin containing amine oxidoreductase
NAEKNMFH_00958 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NAEKNMFH_00959 1.23e-298 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NAEKNMFH_00960 3.12e-117 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
NAEKNMFH_00961 1.55e-94 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
NAEKNMFH_00962 0.0 - - - S - - - domain protein
NAEKNMFH_00963 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NAEKNMFH_00964 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NAEKNMFH_00965 2.07e-162 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NAEKNMFH_00966 3.61e-171 glnR - - KT - - - Transcriptional regulatory protein, C terminal
NAEKNMFH_00967 5.6e-170 - - - - - - - -
NAEKNMFH_00969 3.74e-130 mntP - - P - - - Probably functions as a manganese efflux pump
NAEKNMFH_00971 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NAEKNMFH_00972 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NAEKNMFH_00973 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
NAEKNMFH_00974 8.85e-47 - - - - - - - -
NAEKNMFH_00977 9.75e-07 - - - K - - - sequence-specific DNA binding
NAEKNMFH_00979 9.45e-24 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NAEKNMFH_00984 8.63e-60 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NAEKNMFH_00987 2e-43 - - - V - - - HNH endonuclease
NAEKNMFH_00988 3.32e-81 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NAEKNMFH_01003 2.94e-50 - - - L - - - HNH endonuclease
NAEKNMFH_01004 3.04e-11 - - - - - - - -
NAEKNMFH_01005 4.21e-305 - - - S - - - Terminase
NAEKNMFH_01006 8.32e-271 - - - S - - - Phage portal protein, SPP1 Gp6-like
NAEKNMFH_01007 2.18e-106 - - - - - - - -
NAEKNMFH_01009 1.34e-65 - - - - - - - -
NAEKNMFH_01010 2.32e-188 - - - V - - - Phage capsid family
NAEKNMFH_01012 9.4e-61 - - - S - - - Phage protein Gp19/Gp15/Gp42
NAEKNMFH_01013 3.58e-40 - - - - - - - -
NAEKNMFH_01016 7.03e-77 - - - N - - - domain, Protein
NAEKNMFH_01017 1.62e-36 - - - - - - - -
NAEKNMFH_01019 1.02e-95 - - - NT - - - phage tail tape measure protein
NAEKNMFH_01020 1.98e-89 - - - S - - - phage tail
NAEKNMFH_01021 2.49e-219 - - - S - - - Prophage endopeptidase tail
NAEKNMFH_01024 3.31e-143 - - - - - - - -
NAEKNMFH_01025 3.99e-90 - - - - - - - -
NAEKNMFH_01027 4.64e-83 - - - S - - - SPP1 phage holin
NAEKNMFH_01028 3.77e-169 - - - M - - - NLP P60 protein
NAEKNMFH_01029 5.44e-18 - - - S - - - Putative phage holin Dp-1
NAEKNMFH_01030 1.73e-50 - - - - - - - -
NAEKNMFH_01032 1.29e-126 - - - L - - - Phage integrase family
NAEKNMFH_01034 1.7e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NAEKNMFH_01035 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NAEKNMFH_01037 1.21e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAEKNMFH_01038 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NAEKNMFH_01039 2.81e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAEKNMFH_01040 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NAEKNMFH_01041 7.83e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NAEKNMFH_01042 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NAEKNMFH_01043 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NAEKNMFH_01044 1.83e-167 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NAEKNMFH_01045 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
NAEKNMFH_01046 0.0 - - - - - - - -
NAEKNMFH_01047 7.87e-195 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
NAEKNMFH_01048 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NAEKNMFH_01049 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NAEKNMFH_01050 0.0 pccB - - I - - - Carboxyl transferase domain
NAEKNMFH_01051 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
NAEKNMFH_01052 5.82e-130 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NAEKNMFH_01053 8.48e-207 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
NAEKNMFH_01055 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NAEKNMFH_01056 3.14e-155 - - - - - - - -
NAEKNMFH_01057 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NAEKNMFH_01058 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NAEKNMFH_01059 9.98e-147 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
NAEKNMFH_01060 1.78e-121 lemA - - S ko:K03744 - ko00000 LemA family
NAEKNMFH_01061 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NAEKNMFH_01062 8.61e-92 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
NAEKNMFH_01063 7.28e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAEKNMFH_01064 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAEKNMFH_01065 4.93e-128 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NAEKNMFH_01066 7.29e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NAEKNMFH_01067 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
NAEKNMFH_01068 2.77e-212 - - - L - - - Transposase and inactivated derivatives IS30 family
NAEKNMFH_01069 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
NAEKNMFH_01070 1.85e-239 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
NAEKNMFH_01071 9.04e-186 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NAEKNMFH_01072 2.23e-164 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NAEKNMFH_01073 1.78e-120 - - - D - - - nuclear chromosome segregation
NAEKNMFH_01074 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NAEKNMFH_01075 1.19e-232 - - - L - - - Excalibur calcium-binding domain
NAEKNMFH_01076 1.97e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAEKNMFH_01077 7.42e-311 - - - EGP - - - Major Facilitator Superfamily
NAEKNMFH_01078 1.71e-138 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NAEKNMFH_01079 3.6e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAEKNMFH_01080 8.96e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NAEKNMFH_01081 2.48e-309 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NAEKNMFH_01082 3.28e-166 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NAEKNMFH_01083 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
NAEKNMFH_01084 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NAEKNMFH_01085 1.89e-233 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NAEKNMFH_01086 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAEKNMFH_01087 2.23e-219 - - - S - - - Protein conserved in bacteria
NAEKNMFH_01089 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
NAEKNMFH_01091 0.0 - - - G - - - BNR repeat-like domain
NAEKNMFH_01092 1.45e-235 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
NAEKNMFH_01093 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NAEKNMFH_01094 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NAEKNMFH_01096 0.0 - - - T - - - Forkhead associated domain
NAEKNMFH_01097 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
NAEKNMFH_01098 1.66e-55 - - - - - - - -
NAEKNMFH_01099 2.1e-141 - - - NO - - - SAF
NAEKNMFH_01100 1.88e-51 - - - S - - - Putative regulatory protein
NAEKNMFH_01101 9.44e-153 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
NAEKNMFH_01102 1.2e-191 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NAEKNMFH_01103 3.31e-265 - - - - - - - -
NAEKNMFH_01104 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NAEKNMFH_01105 4.56e-166 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NAEKNMFH_01106 4.72e-54 yeaC - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NAEKNMFH_01110 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
NAEKNMFH_01111 3.03e-277 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NAEKNMFH_01112 5.9e-80 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
NAEKNMFH_01113 2.73e-283 dapC - - E - - - Aminotransferase class I and II
NAEKNMFH_01114 6.06e-303 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAEKNMFH_01116 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
NAEKNMFH_01117 2.32e-146 yigZ - - S - - - Uncharacterized protein family UPF0029
NAEKNMFH_01118 1.46e-152 - - - - - - - -
NAEKNMFH_01119 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NAEKNMFH_01120 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NAEKNMFH_01121 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NAEKNMFH_01122 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NAEKNMFH_01123 3.54e-297 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NAEKNMFH_01124 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NAEKNMFH_01125 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NAEKNMFH_01126 1.26e-207 - - - S - - - YwiC-like protein
NAEKNMFH_01127 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NAEKNMFH_01128 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NAEKNMFH_01129 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NAEKNMFH_01130 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NAEKNMFH_01131 6.65e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NAEKNMFH_01132 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NAEKNMFH_01133 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NAEKNMFH_01134 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NAEKNMFH_01135 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NAEKNMFH_01136 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NAEKNMFH_01137 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NAEKNMFH_01138 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NAEKNMFH_01139 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NAEKNMFH_01140 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NAEKNMFH_01141 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAEKNMFH_01142 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NAEKNMFH_01143 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NAEKNMFH_01144 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NAEKNMFH_01145 2.19e-146 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NAEKNMFH_01146 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
NAEKNMFH_01147 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NAEKNMFH_01148 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NAEKNMFH_01149 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NAEKNMFH_01150 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NAEKNMFH_01151 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NAEKNMFH_01152 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NAEKNMFH_01153 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NAEKNMFH_01154 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAEKNMFH_01155 4.39e-94 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NAEKNMFH_01156 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
NAEKNMFH_01157 4.06e-219 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NAEKNMFH_01158 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
NAEKNMFH_01159 1.58e-198 - - - E - - - Transglutaminase/protease-like homologues
NAEKNMFH_01161 4.97e-186 tnp3503b - - L - - - Transposase and inactivated derivatives
NAEKNMFH_01162 6.58e-227 - - - - - - - -
NAEKNMFH_01163 5.49e-240 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NAEKNMFH_01164 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NAEKNMFH_01165 5.87e-116 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NAEKNMFH_01166 4.25e-293 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NAEKNMFH_01167 6.39e-298 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
NAEKNMFH_01168 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NAEKNMFH_01169 1.63e-140 - - - - - - - -
NAEKNMFH_01170 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
NAEKNMFH_01171 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NAEKNMFH_01172 3.42e-258 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAEKNMFH_01173 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NAEKNMFH_01174 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAEKNMFH_01175 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NAEKNMFH_01179 8.64e-05 - - - O ko:K18546 - ko00000,ko01000,ko01002 Peptidase s1 and s6 chymotrypsin hap
NAEKNMFH_01180 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
NAEKNMFH_01181 5.91e-197 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NAEKNMFH_01182 3.25e-273 - - - I - - - Diacylglycerol kinase catalytic domain
NAEKNMFH_01183 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NAEKNMFH_01184 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NAEKNMFH_01185 2.32e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NAEKNMFH_01187 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
NAEKNMFH_01189 2.95e-121 - - - - - - - -
NAEKNMFH_01190 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NAEKNMFH_01191 7.54e-240 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
NAEKNMFH_01192 2.48e-182 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NAEKNMFH_01194 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NAEKNMFH_01195 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
NAEKNMFH_01196 0.0 tcsS3 - - KT - - - PspC domain
NAEKNMFH_01197 0.0 pspC - - KT - - - PspC domain
NAEKNMFH_01198 4.54e-196 - - - - - - - -
NAEKNMFH_01199 1.3e-143 - - - S - - - Protein of unknown function (DUF4125)
NAEKNMFH_01200 0.0 - - - S - - - Domain of unknown function (DUF4037)
NAEKNMFH_01201 4.31e-277 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
NAEKNMFH_01203 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NAEKNMFH_01204 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NAEKNMFH_01205 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NAEKNMFH_01207 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NAEKNMFH_01208 9.24e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NAEKNMFH_01209 4.6e-53 - - - - - - - -
NAEKNMFH_01210 6.07e-274 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NAEKNMFH_01211 1.18e-228 - - - S - - - CHAP domain
NAEKNMFH_01212 1.14e-144 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NAEKNMFH_01213 1.31e-244 - - - T - - - Universal stress protein family
NAEKNMFH_01214 5.29e-95 - - - O - - - OsmC-like protein
NAEKNMFH_01215 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NAEKNMFH_01216 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
NAEKNMFH_01217 2e-125 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
NAEKNMFH_01218 4.43e-250 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NAEKNMFH_01219 1.23e-60 - - - E - - - Branched-chain amino acid transport protein (AzlD)
NAEKNMFH_01220 5.06e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_01221 6.48e-269 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NAEKNMFH_01222 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NAEKNMFH_01223 2.57e-14 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NAEKNMFH_01224 1.23e-231 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NAEKNMFH_01225 5.77e-77 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NAEKNMFH_01226 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NAEKNMFH_01227 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NAEKNMFH_01228 4.4e-23 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
NAEKNMFH_01229 3.37e-28 - - - S - - - Helix-turn-helix domain
NAEKNMFH_01231 6.71e-196 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NAEKNMFH_01232 1.14e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NAEKNMFH_01233 1.7e-105 - - - S - - - Domain of unknown function (DUF4190)
NAEKNMFH_01236 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NAEKNMFH_01237 1.89e-227 - - - M - - - Glycosyltransferase like family 2
NAEKNMFH_01238 0.0 - - - S - - - AI-2E family transporter
NAEKNMFH_01239 3.97e-295 - - - M - - - Glycosyl transferase family 21
NAEKNMFH_01240 2.26e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01241 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NAEKNMFH_01242 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
NAEKNMFH_01243 2.1e-270 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NAEKNMFH_01244 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NAEKNMFH_01245 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NAEKNMFH_01246 2.39e-129 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NAEKNMFH_01247 1.78e-207 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NAEKNMFH_01248 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NAEKNMFH_01249 2.35e-107 - - - S - - - Protein of unknown function (DUF3180)
NAEKNMFH_01250 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
NAEKNMFH_01251 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
NAEKNMFH_01252 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
NAEKNMFH_01254 3.55e-147 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NAEKNMFH_01255 1.71e-65 - - - S - - - Protein of unknown function (DUF979)
NAEKNMFH_01256 1.86e-101 - - - S - - - DUF218 domain
NAEKNMFH_01258 8.16e-63 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
NAEKNMFH_01259 1.49e-63 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
NAEKNMFH_01260 8.44e-201 - - - I - - - alpha/beta hydrolase fold
NAEKNMFH_01261 2.12e-36 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
NAEKNMFH_01262 2.95e-25 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
NAEKNMFH_01263 0.0 - - - S - - - ATPases associated with a variety of cellular activities
NAEKNMFH_01264 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NAEKNMFH_01266 1.52e-91 - - - EGP - - - Major facilitator superfamily
NAEKNMFH_01267 1.12e-47 - - - C - - - Aldo/keto reductase family
NAEKNMFH_01268 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
NAEKNMFH_01269 5.38e-273 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_01270 4.1e-188 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NAEKNMFH_01271 1.13e-183 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NAEKNMFH_01272 1.23e-210 - - - EG - - - EamA-like transporter family
NAEKNMFH_01273 0.0 - - - JKL - - - helicase superfamily c-terminal domain
NAEKNMFH_01274 2.4e-183 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NAEKNMFH_01275 9.28e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
NAEKNMFH_01276 7.2e-144 - - - - - - - -
NAEKNMFH_01277 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
NAEKNMFH_01278 2.36e-170 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NAEKNMFH_01279 1.95e-67 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
NAEKNMFH_01281 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NAEKNMFH_01282 3.2e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NAEKNMFH_01283 6.73e-234 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NAEKNMFH_01284 1.11e-79 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
NAEKNMFH_01285 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
NAEKNMFH_01286 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
NAEKNMFH_01287 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NAEKNMFH_01288 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
NAEKNMFH_01289 1.16e-28 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NAEKNMFH_01290 7.86e-53 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NAEKNMFH_01291 7.8e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NAEKNMFH_01292 2.73e-203 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NAEKNMFH_01293 0.0 - - - L - - - PIF1-like helicase
NAEKNMFH_01295 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NAEKNMFH_01296 5.42e-219 - - - - - - - -
NAEKNMFH_01297 1.28e-152 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NAEKNMFH_01298 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
NAEKNMFH_01299 8.85e-193 - - - S - - - Short repeat of unknown function (DUF308)
NAEKNMFH_01300 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NAEKNMFH_01301 9.67e-317 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
NAEKNMFH_01302 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
NAEKNMFH_01303 1.04e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
NAEKNMFH_01304 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NAEKNMFH_01305 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01306 1.66e-286 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NAEKNMFH_01307 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
NAEKNMFH_01308 3.15e-298 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NAEKNMFH_01309 2.57e-310 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
NAEKNMFH_01310 1.77e-178 hflK - - O - - - prohibitin homologues
NAEKNMFH_01311 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
NAEKNMFH_01312 2.38e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NAEKNMFH_01313 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NAEKNMFH_01314 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 DEAD-like helicases superfamily
NAEKNMFH_01315 4.71e-133 cas5d - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
NAEKNMFH_01316 5.62e-304 - - - S - - - CRISPR-associated protein (Cas_Csd1)
NAEKNMFH_01317 1.9e-189 - - - L ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
NAEKNMFH_01318 2.82e-140 cas4 3.1.12.1 - L ko:K07464,ko:K15342 - ko00000,ko01000,ko02048,ko03400 Domain of unknown function DUF83
NAEKNMFH_01319 2.35e-225 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAEKNMFH_01320 1.88e-55 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAEKNMFH_01323 1.47e-11 - - - S - - - Protein of unknown function (DUF2442)
NAEKNMFH_01324 3.2e-32 - - - S - - - Domain of unknown function (DUF4160)
NAEKNMFH_01325 1.18e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
NAEKNMFH_01327 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NAEKNMFH_01328 1.35e-24 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NAEKNMFH_01329 2.17e-243 - - - K - - - Periplasmic binding protein domain
NAEKNMFH_01330 2.09e-54 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NAEKNMFH_01331 9.49e-77 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NAEKNMFH_01332 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NAEKNMFH_01333 3.18e-90 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
NAEKNMFH_01334 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NAEKNMFH_01335 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NAEKNMFH_01336 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NAEKNMFH_01337 5.73e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_01338 5.02e-208 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_01339 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
NAEKNMFH_01340 1.57e-199 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01341 5.1e-240 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAEKNMFH_01342 1.53e-123 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NAEKNMFH_01343 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NAEKNMFH_01344 2.06e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NAEKNMFH_01345 3.93e-158 - - - L - - - Protein of unknown function (DUF1524)
NAEKNMFH_01346 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
NAEKNMFH_01347 2.42e-16 chiA 3.1.6.1, 3.2.1.14, 3.2.1.17, 3.2.1.23, 3.2.1.4 AA10,CBM15,CBM73,GH18,GH5,GH9 S ko:K01130,ko:K01179,ko:K01183,ko:K01190,ko:K03933,ko:K12308,ko:K13381 ko00052,ko00140,ko00500,ko00511,ko00520,ko00600,ko01100,map00052,map00140,map00500,map00511,map00520,map00600,map01100 ko00000,ko00001,ko01000 dextransucrase activity
NAEKNMFH_01348 1.61e-258 - - - K - - - helix_turn _helix lactose operon repressor
NAEKNMFH_01349 8.86e-106 - - - G - - - Glycosyl hydrolases family 43
NAEKNMFH_01352 2.33e-143 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NAEKNMFH_01353 8.26e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NAEKNMFH_01354 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NAEKNMFH_01355 6.43e-11 tnp3521a2 - - L - - - Integrase core domain
NAEKNMFH_01356 4.58e-269 - - - K - - - helix_turn _helix lactose operon repressor
NAEKNMFH_01357 6.64e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAEKNMFH_01358 1.03e-201 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NAEKNMFH_01359 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NAEKNMFH_01360 8.39e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
NAEKNMFH_01361 3.64e-219 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
NAEKNMFH_01362 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NAEKNMFH_01363 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NAEKNMFH_01364 4.95e-221 - - - K - - - Putative sugar-binding domain
NAEKNMFH_01366 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NAEKNMFH_01367 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01368 7.79e-27 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
NAEKNMFH_01369 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
NAEKNMFH_01370 4.87e-155 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
NAEKNMFH_01372 6.19e-263 - - - - - - - -
NAEKNMFH_01374 2.09e-272 - - - - - - - -
NAEKNMFH_01375 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NAEKNMFH_01378 5.15e-224 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
NAEKNMFH_01379 3.26e-151 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NAEKNMFH_01380 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NAEKNMFH_01381 1.17e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NAEKNMFH_01384 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NAEKNMFH_01385 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
NAEKNMFH_01386 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NAEKNMFH_01387 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NAEKNMFH_01388 2.17e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NAEKNMFH_01389 3.01e-184 - - - - - - - -
NAEKNMFH_01390 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NAEKNMFH_01391 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
NAEKNMFH_01392 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
NAEKNMFH_01393 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
NAEKNMFH_01394 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NAEKNMFH_01395 4.14e-212 - - - P - - - Cation efflux family
NAEKNMFH_01396 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NAEKNMFH_01397 2.84e-284 - - - S - - - Endonuclease/Exonuclease/phosphatase family
NAEKNMFH_01398 1.36e-131 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NAEKNMFH_01399 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NAEKNMFH_01400 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NAEKNMFH_01401 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NAEKNMFH_01402 9.23e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NAEKNMFH_01403 2.32e-215 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NAEKNMFH_01404 1.61e-108 - - - O - - - Hsp20/alpha crystallin family
NAEKNMFH_01405 2.74e-139 - - - S ko:K07078 - ko00000 Nitroreductase family
NAEKNMFH_01406 7.31e-154 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
NAEKNMFH_01407 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
NAEKNMFH_01408 0.0 - - - - - - - -
NAEKNMFH_01411 7.09e-278 steT - - E ko:K03294 - ko00000 amino acid
NAEKNMFH_01412 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
NAEKNMFH_01413 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NAEKNMFH_01414 7.72e-256 - - - G - - - pfkB family carbohydrate kinase
NAEKNMFH_01417 8.26e-307 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NAEKNMFH_01418 8.3e-171 - - - K - - - helix_turn_helix, mercury resistance
NAEKNMFH_01420 2.07e-71 - - - L - - - RelB antitoxin
NAEKNMFH_01421 1.07e-299 - - - K - - - Helix-turn-helix XRE-family like proteins
NAEKNMFH_01422 3.18e-16 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
NAEKNMFH_01427 3.96e-44 - - - - - - - -
NAEKNMFH_01429 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NAEKNMFH_01430 1.04e-59 - - - K - - - Transcriptional regulator
NAEKNMFH_01432 9.14e-13 - - - M - - - Belongs to the glycosyl hydrolase 28 family
NAEKNMFH_01433 1.67e-295 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
NAEKNMFH_01434 3.75e-304 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_01435 8.74e-153 - - - K - - - Bacterial regulatory proteins, tetR family
NAEKNMFH_01436 1.04e-169 - - - M - - - Mechanosensitive ion channel
NAEKNMFH_01437 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NAEKNMFH_01439 5.72e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
NAEKNMFH_01440 1.18e-188 - - - S - - - Domain of unknown function (DUF4854)
NAEKNMFH_01441 1.31e-270 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NAEKNMFH_01442 0.0 - - - M - - - LPXTG cell wall anchor motif
NAEKNMFH_01443 0.0 - - - M - - - domain protein
NAEKNMFH_01444 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
NAEKNMFH_01445 8.33e-189 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NAEKNMFH_01446 1.72e-247 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NAEKNMFH_01447 7.74e-176 - - - M - - - Protein of unknown function (DUF3152)
NAEKNMFH_01448 1.28e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NAEKNMFH_01450 7.2e-95 - - - E - - - Domain of unknown function (DUF5011)
NAEKNMFH_01451 2.59e-41 - - - S - - - Parallel beta-helix repeats
NAEKNMFH_01452 6.71e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NAEKNMFH_01453 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NAEKNMFH_01454 2.38e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NAEKNMFH_01455 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NAEKNMFH_01456 1.74e-244 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
NAEKNMFH_01457 1.28e-167 - - - - - - - -
NAEKNMFH_01458 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NAEKNMFH_01459 1.26e-242 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAEKNMFH_01460 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
NAEKNMFH_01461 2.02e-252 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NAEKNMFH_01462 1.94e-276 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NAEKNMFH_01463 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAEKNMFH_01464 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NAEKNMFH_01465 6.4e-164 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NAEKNMFH_01466 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NAEKNMFH_01468 2.89e-294 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
NAEKNMFH_01469 1.75e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NAEKNMFH_01470 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NAEKNMFH_01471 3.12e-274 - - - K - - - Psort location Cytoplasmic, score
NAEKNMFH_01472 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
NAEKNMFH_01473 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NAEKNMFH_01474 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
NAEKNMFH_01475 2.34e-303 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NAEKNMFH_01476 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NAEKNMFH_01477 0.0 - - - V - - - Efflux ABC transporter, permease protein
NAEKNMFH_01478 1.59e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01479 8.09e-76 - - - - - - - -
NAEKNMFH_01480 5.49e-85 - - - - - - - -
NAEKNMFH_01481 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
NAEKNMFH_01482 5.51e-239 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NAEKNMFH_01483 6.26e-305 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NAEKNMFH_01484 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NAEKNMFH_01485 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NAEKNMFH_01486 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NAEKNMFH_01487 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NAEKNMFH_01488 4.58e-229 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NAEKNMFH_01489 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
NAEKNMFH_01490 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
NAEKNMFH_01492 1.07e-193 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
NAEKNMFH_01493 1.58e-23 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
NAEKNMFH_01494 1.17e-25 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
NAEKNMFH_01495 4.87e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
NAEKNMFH_01497 5.52e-152 - - - S - - - CYTH
NAEKNMFH_01498 1.03e-213 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
NAEKNMFH_01499 1.68e-231 - - - - - - - -
NAEKNMFH_01500 1.03e-242 - - - - - - - -
NAEKNMFH_01501 1.54e-223 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
NAEKNMFH_01502 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NAEKNMFH_01503 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NAEKNMFH_01504 3e-184 - - - - - - - -
NAEKNMFH_01505 1.69e-169 - - - K - - - Bacterial regulatory proteins, tetR family
NAEKNMFH_01506 1.41e-286 - - - G - - - Transmembrane secretion effector
NAEKNMFH_01507 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAEKNMFH_01508 3.04e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
NAEKNMFH_01509 8.24e-250 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NAEKNMFH_01511 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_01512 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAEKNMFH_01513 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAEKNMFH_01514 1.59e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
NAEKNMFH_01515 1.94e-316 - - - S - - - Calcineurin-like phosphoesterase
NAEKNMFH_01518 5.98e-104 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NAEKNMFH_01519 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NAEKNMFH_01521 1.65e-159 - - - S - - - HAD hydrolase, family IA, variant 3
NAEKNMFH_01522 5.05e-258 - - - P - - - NMT1/THI5 like
NAEKNMFH_01523 4.1e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
NAEKNMFH_01524 2.1e-195 - - - - - - - -
NAEKNMFH_01525 9.49e-163 - - - G - - - Phosphoglycerate mutase family
NAEKNMFH_01526 0.0 - - - EGP - - - Major Facilitator Superfamily
NAEKNMFH_01527 6.15e-127 - - - S - - - GtrA-like protein
NAEKNMFH_01528 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
NAEKNMFH_01529 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
NAEKNMFH_01530 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NAEKNMFH_01531 4.65e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NAEKNMFH_01532 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
NAEKNMFH_01533 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NAEKNMFH_01534 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_01535 8.73e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NAEKNMFH_01536 7.35e-243 - - - C - - - Aldo/keto reductase family
NAEKNMFH_01537 2.62e-41 - - - M - - - F5/8 type C domain
NAEKNMFH_01538 4.74e-69 - - - - - - - -
NAEKNMFH_01540 4.3e-144 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
NAEKNMFH_01541 1.11e-148 - - - K - - - WHG domain
NAEKNMFH_01542 1.56e-37 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
NAEKNMFH_01543 0.0 - - - EGP - - - Major Facilitator Superfamily
NAEKNMFH_01544 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NAEKNMFH_01545 1.51e-190 - - - L ko:K07454 - ko00000 HNH endonuclease
NAEKNMFH_01546 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NAEKNMFH_01547 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NAEKNMFH_01549 7.94e-111 - - - L ko:K07485 - ko00000 Transposase
NAEKNMFH_01550 7.13e-56 - - - O - - - Glutaredoxin
NAEKNMFH_01551 2.1e-191 - - - S ko:K07058 - ko00000 Virulence factor BrkB
NAEKNMFH_01552 2.78e-127 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
NAEKNMFH_01553 4.44e-51 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NAEKNMFH_01554 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NAEKNMFH_01555 1.05e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NAEKNMFH_01556 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NAEKNMFH_01557 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NAEKNMFH_01558 7.06e-132 - - - K - - - Transcriptional regulator C-terminal region
NAEKNMFH_01559 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
NAEKNMFH_01560 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NAEKNMFH_01562 9.44e-234 - - - S - - - Protein of unknown function (DUF559)
NAEKNMFH_01563 1.69e-258 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NAEKNMFH_01564 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NAEKNMFH_01565 0.0 - - - EGP - - - Sugar (and other) transporter
NAEKNMFH_01566 0.0 scrT - - G - - - Transporter major facilitator family protein
NAEKNMFH_01567 1.81e-98 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
NAEKNMFH_01568 6.11e-252 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_01569 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NAEKNMFH_01570 1.24e-210 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NAEKNMFH_01571 9.71e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NAEKNMFH_01572 3.59e-252 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NAEKNMFH_01573 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NAEKNMFH_01574 7.29e-125 - - - - - - - -
NAEKNMFH_01575 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
NAEKNMFH_01576 4.68e-78 - - - S - - - Bacterial mobilisation protein (MobC)
NAEKNMFH_01577 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NAEKNMFH_01578 2.4e-230 - - - V - - - Abi-like protein
NAEKNMFH_01579 3.13e-291 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NAEKNMFH_01581 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
NAEKNMFH_01582 0.0 - - - - - - - -
NAEKNMFH_01583 5.43e-09 - - - - - - - -
NAEKNMFH_01585 1.57e-245 int8 - - L - - - Phage integrase family
NAEKNMFH_01586 8.93e-93 - - - S - - - Domain of unknown function (DUF4411)
NAEKNMFH_01587 2.11e-160 - - - E - - - IrrE N-terminal-like domain
NAEKNMFH_01589 3.47e-216 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NAEKNMFH_01590 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
NAEKNMFH_01591 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NAEKNMFH_01592 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
NAEKNMFH_01593 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NAEKNMFH_01595 1.23e-45 - - - L - - - Transposase, Mutator family
NAEKNMFH_01597 1.06e-49 - - - M - - - Glycosyl hydrolases family 25
NAEKNMFH_01598 3.9e-43 - - - M - - - Glycosyl hydrolases family 25
NAEKNMFH_01599 3.09e-44 - - - - - - - -
NAEKNMFH_01600 1.62e-143 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NAEKNMFH_01601 9.1e-97 - - - L - - - HindVP restriction endonuclease
NAEKNMFH_01604 1.05e-112 tnp3521a2 - - L - - - Integrase core domain
NAEKNMFH_01605 1.4e-184 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
NAEKNMFH_01606 5.39e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NAEKNMFH_01607 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NAEKNMFH_01608 2.31e-185 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NAEKNMFH_01609 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
NAEKNMFH_01610 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
NAEKNMFH_01611 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
NAEKNMFH_01612 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NAEKNMFH_01614 2.55e-222 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAEKNMFH_01615 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
NAEKNMFH_01616 1.06e-197 - - - - - - - -
NAEKNMFH_01617 2.22e-231 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NAEKNMFH_01618 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NAEKNMFH_01619 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
NAEKNMFH_01620 8.38e-129 - - - L - - - Helix-turn-helix domain
NAEKNMFH_01621 2.18e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NAEKNMFH_01622 7.97e-223 - - - K - - - Psort location Cytoplasmic, score
NAEKNMFH_01623 0.0 - - - KLT - - - Protein tyrosine kinase
NAEKNMFH_01624 2.59e-201 - - - O - - - Thioredoxin
NAEKNMFH_01626 1.69e-280 rpfB - - S ko:K21688 - ko00000 G5
NAEKNMFH_01627 2.1e-216 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NAEKNMFH_01628 2.19e-212 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NAEKNMFH_01629 2.83e-145 - - - S - - - LytR cell envelope-related transcriptional attenuator
NAEKNMFH_01630 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
NAEKNMFH_01631 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
NAEKNMFH_01632 0.0 - - - M - - - Conserved repeat domain
NAEKNMFH_01633 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
NAEKNMFH_01634 3.93e-258 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NAEKNMFH_01635 1.7e-313 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NAEKNMFH_01636 1.05e-229 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NAEKNMFH_01637 4.29e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NAEKNMFH_01638 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
NAEKNMFH_01639 2.11e-227 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
NAEKNMFH_01640 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NAEKNMFH_01641 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NAEKNMFH_01642 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NAEKNMFH_01643 5.36e-306 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NAEKNMFH_01644 1.85e-123 - - - S - - - Protein of unknown function (DUF721)
NAEKNMFH_01645 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAEKNMFH_01646 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAEKNMFH_01647 6.81e-103 - - - S - - - Transmembrane domain of unknown function (DUF3566)
NAEKNMFH_01650 4.34e-240 - - - G - - - Glycosyl hydrolases family 43
NAEKNMFH_01651 1.09e-238 - - - K - - - Periplasmic binding protein domain
NAEKNMFH_01652 7.56e-290 - - - I - - - Serine aminopeptidase, S33
NAEKNMFH_01653 2.53e-10 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_01654 1.47e-11 - - - S - - - Protein of unknown function (DUF2442)
NAEKNMFH_01655 4.84e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
NAEKNMFH_01657 9.16e-05 - - - M - - - PA domain
NAEKNMFH_01658 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NAEKNMFH_01659 3.65e-159 gntR - - K - - - FCD
NAEKNMFH_01660 6.17e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NAEKNMFH_01661 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
NAEKNMFH_01664 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
NAEKNMFH_01665 1.03e-243 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_01666 6.23e-102 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NAEKNMFH_01667 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NAEKNMFH_01668 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NAEKNMFH_01669 2.96e-175 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
NAEKNMFH_01670 4.45e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NAEKNMFH_01671 4.01e-240 - - - EG - - - EamA-like transporter family
NAEKNMFH_01672 9.63e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
NAEKNMFH_01673 1.78e-104 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_01674 1.23e-153 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NAEKNMFH_01675 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
NAEKNMFH_01676 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
NAEKNMFH_01677 1.13e-307 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NAEKNMFH_01678 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NAEKNMFH_01679 0.0 - - - S - - - Threonine/Serine exporter, ThrE
NAEKNMFH_01680 1.72e-224 - - - S - - - Amidohydrolase family
NAEKNMFH_01681 3.36e-248 - - - S - - - Protein conserved in bacteria
NAEKNMFH_01682 6.93e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NAEKNMFH_01683 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
NAEKNMFH_01684 6.08e-114 - - - K - - - LytTr DNA-binding domain
NAEKNMFH_01685 5.9e-113 - - - T - - - protein histidine kinase activity
NAEKNMFH_01686 5.04e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NAEKNMFH_01687 8.14e-39 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NAEKNMFH_01688 0.0 - - - M - - - Glycosyl hydrolases family 25
NAEKNMFH_01689 5.91e-234 - - GT2 M ko:K13670 - ko00000,ko01000 Glycosyltransferase like family 2
NAEKNMFH_01690 3.77e-177 tnp3521a2 - - L - - - Integrase core domain
NAEKNMFH_01691 6.79e-68 - - - L ko:K07483 - ko00000 Transposase
NAEKNMFH_01692 2.82e-162 istB - - L - - - IstB-like ATP binding protein
NAEKNMFH_01693 1.96e-158 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01694 2.46e-153 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01695 3.24e-57 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01696 2.28e-57 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01697 0.0 - - - S - - - Glucosyl transferase GtrII
NAEKNMFH_01698 0.0 - - - S - - - Polysaccharide pyruvyl transferase
NAEKNMFH_01699 0.0 - - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
NAEKNMFH_01700 2.1e-246 - - - I - - - Acyltransferase family
NAEKNMFH_01701 1.44e-92 - 1.1.1.339 - GM ko:K19180 ko00523,ko01130,map00523,map01130 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NAEKNMFH_01702 5.35e-107 - - - L ko:K07483,ko:K07497 - ko00000 transposase activity
NAEKNMFH_01703 2.01e-153 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01704 3.08e-207 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01705 0.0 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01706 2.69e-183 istB - - L - - - IstB-like ATP binding protein
NAEKNMFH_01707 2.3e-169 istB - - L - - - IstB-like ATP binding protein
NAEKNMFH_01708 2.98e-130 - - - L - - - PFAM Integrase catalytic
NAEKNMFH_01709 6.8e-250 - - - M - - - Glycosyltransferase like family 2
NAEKNMFH_01710 1.79e-138 - - - - - - - -
NAEKNMFH_01711 1.79e-110 - - - E - - - IrrE N-terminal-like domain
NAEKNMFH_01713 1.72e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NAEKNMFH_01714 3.23e-307 - - - S - - - Putative ABC-transporter type IV
NAEKNMFH_01715 2.24e-103 - - - - - - - -
NAEKNMFH_01716 3.82e-47 - - - Q - - - phosphatase activity
NAEKNMFH_01717 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
NAEKNMFH_01718 1.29e-66 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NAEKNMFH_01719 5.95e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NAEKNMFH_01720 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NAEKNMFH_01722 1.13e-86 - - - S - - - haloacid dehalogenase-like hydrolase
NAEKNMFH_01723 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
NAEKNMFH_01724 8.08e-103 - - - S - - - FMN_bind
NAEKNMFH_01725 7.76e-191 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_01726 3.5e-276 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NAEKNMFH_01727 9.25e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NAEKNMFH_01728 1.02e-294 - - - S - - - Predicted membrane protein (DUF2318)
NAEKNMFH_01729 1.67e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
NAEKNMFH_01730 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
NAEKNMFH_01731 8.33e-31 - - - G - - - MFS/sugar transport protein
NAEKNMFH_01732 1.23e-257 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NAEKNMFH_01733 4.74e-110 - - - S - - - Fic/DOC family
NAEKNMFH_01734 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAEKNMFH_01735 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
NAEKNMFH_01736 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NAEKNMFH_01737 3.65e-273 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NAEKNMFH_01738 2.08e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NAEKNMFH_01739 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NAEKNMFH_01740 4.2e-247 - - - I - - - PAP2 superfamily
NAEKNMFH_01741 0.0 - - - M - - - PA domain
NAEKNMFH_01742 6.63e-175 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NAEKNMFH_01743 6.29e-296 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NAEKNMFH_01744 0.0 pbp5 - - M - - - Transglycosylase
NAEKNMFH_01745 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NAEKNMFH_01746 0.0 - - - S - - - Calcineurin-like phosphoesterase
NAEKNMFH_01747 3.11e-19 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
NAEKNMFH_01748 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
NAEKNMFH_01749 1.77e-148 - - - - - - - -
NAEKNMFH_01750 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NAEKNMFH_01752 1.42e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NAEKNMFH_01753 2.29e-176 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NAEKNMFH_01754 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NAEKNMFH_01755 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
NAEKNMFH_01756 1.61e-274 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
NAEKNMFH_01757 3.62e-73 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
NAEKNMFH_01758 3.96e-55 - - - S - - - Protein of unknown function (DUF4244)
NAEKNMFH_01759 1.3e-20 - - - NU - - - Type II secretion system (T2SS), protein F
NAEKNMFH_01761 2.62e-157 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
NAEKNMFH_01762 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
NAEKNMFH_01763 1.34e-196 - - - D - - - bacterial-type flagellum organization
NAEKNMFH_01765 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NAEKNMFH_01766 1.57e-282 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
NAEKNMFH_01767 5.26e-130 - - - - - - - -
NAEKNMFH_01768 4.48e-75 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NAEKNMFH_01769 8.16e-268 - - - S - - - Glycosyltransferase, group 2 family protein
NAEKNMFH_01770 0.0 - - - - - - - -
NAEKNMFH_01771 1.99e-36 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
NAEKNMFH_01772 1.12e-210 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NAEKNMFH_01773 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NAEKNMFH_01774 0.0 - - - H - - - Protein of unknown function (DUF4012)
NAEKNMFH_01775 0.0 - - - V - - - ABC transporter permease
NAEKNMFH_01776 6.91e-271 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NAEKNMFH_01777 3.42e-178 - - - T ko:K06950 - ko00000 HD domain
NAEKNMFH_01778 3.34e-211 - - - S - - - Glutamine amidotransferase domain
NAEKNMFH_01780 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NAEKNMFH_01781 1.29e-235 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
NAEKNMFH_01782 4e-230 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
NAEKNMFH_01783 1.18e-51 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
NAEKNMFH_01785 9.83e-100 - - - K - - - Transcriptional regulator
NAEKNMFH_01786 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NAEKNMFH_01787 7.68e-170 - - - - - - - -
NAEKNMFH_01788 1.6e-83 - - - - - - - -
NAEKNMFH_01789 5.14e-219 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NAEKNMFH_01790 1.79e-161 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NAEKNMFH_01792 1.17e-171 - - - S - - - HAD hydrolase, family IA, variant 3
NAEKNMFH_01793 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
NAEKNMFH_01794 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NAEKNMFH_01795 6.42e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
NAEKNMFH_01796 3.86e-236 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
NAEKNMFH_01797 8.46e-88 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NAEKNMFH_01798 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NAEKNMFH_01799 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
NAEKNMFH_01800 5.54e-243 - - - K - - - Psort location Cytoplasmic, score
NAEKNMFH_01802 1.84e-180 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NAEKNMFH_01803 5.82e-89 - - - S - - - Protein of unknown function (DUF4235)
NAEKNMFH_01804 7.71e-182 nfrA - - C - - - Nitroreductase family
NAEKNMFH_01805 2.45e-61 - - - - - - - -
NAEKNMFH_01806 1.28e-30 - - - - - - - -
NAEKNMFH_01807 2.49e-14 - - - L ko:K07485 - ko00000 Transposase
NAEKNMFH_01808 1.9e-51 - - - L - - - Transposase
NAEKNMFH_01809 9.29e-220 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NAEKNMFH_01810 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NAEKNMFH_01811 3.56e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NAEKNMFH_01812 2.32e-197 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NAEKNMFH_01813 1.21e-306 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NAEKNMFH_01814 1.63e-121 - - - L - - - Transposase and inactivated derivatives IS30 family
NAEKNMFH_01815 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NAEKNMFH_01816 1.53e-24 yccF - - S - - - Inner membrane component domain
NAEKNMFH_01817 1.9e-17 - - - - - - - -
NAEKNMFH_01818 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NAEKNMFH_01819 7.04e-57 - - - L - - - Integrase core domain
NAEKNMFH_01820 4.03e-56 istB - - L - - - IstB-like ATP binding protein
NAEKNMFH_01821 6.2e-56 - - - L ko:K07485 - ko00000 Transposase
NAEKNMFH_01822 2.31e-45 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
NAEKNMFH_01823 5.53e-96 - - - I - - - Sterol carrier protein
NAEKNMFH_01824 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NAEKNMFH_01826 7.68e-47 - - - - - - - -
NAEKNMFH_01827 4.85e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
NAEKNMFH_01828 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
NAEKNMFH_01829 8.05e-100 crgA - - D - - - Involved in cell division
NAEKNMFH_01830 2.05e-183 - - - S - - - Bacterial protein of unknown function (DUF881)
NAEKNMFH_01831 5.65e-296 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NAEKNMFH_01832 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
NAEKNMFH_01833 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NAEKNMFH_01834 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NAEKNMFH_01835 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NAEKNMFH_01836 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NAEKNMFH_01837 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
NAEKNMFH_01838 1.18e-121 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NAEKNMFH_01839 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
NAEKNMFH_01840 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
NAEKNMFH_01841 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NAEKNMFH_01842 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NAEKNMFH_01843 3.44e-263 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
NAEKNMFH_01844 1.59e-215 - - - EG - - - EamA-like transporter family
NAEKNMFH_01845 4.51e-145 - - - - - - - -
NAEKNMFH_01847 4.1e-251 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAEKNMFH_01849 0.0 - - - KL - - - Domain of unknown function (DUF3427)
NAEKNMFH_01850 3.29e-116 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NAEKNMFH_01851 1.67e-62 - - - - - - - -
NAEKNMFH_01852 1.75e-69 - - - S - - - Putative heavy-metal-binding
NAEKNMFH_01853 6.18e-199 - - - I - - - Serine aminopeptidase, S33
NAEKNMFH_01854 4.51e-110 - - - Q - - - Acetyltransferase (GNAT) domain
NAEKNMFH_01855 1.41e-204 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)