ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EHFOKGKC_00001 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EHFOKGKC_00002 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHFOKGKC_00003 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHFOKGKC_00004 1.7e-259 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EHFOKGKC_00005 6.29e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EHFOKGKC_00006 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EHFOKGKC_00007 9.17e-303 ydaM - - M - - - Glycosyl transferase family group 2
EHFOKGKC_00008 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EHFOKGKC_00009 0.0 ydaO - - E - - - amino acid
EHFOKGKC_00010 3.75e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHFOKGKC_00011 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EHFOKGKC_00012 4.42e-11 - - - - - - - -
EHFOKGKC_00014 2.95e-113 - - - - - - - -
EHFOKGKC_00015 4.22e-130 - - - - - - - -
EHFOKGKC_00016 6.14e-53 - - - - - - - -
EHFOKGKC_00017 1.87e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EHFOKGKC_00019 1.95e-45 ydaT - - - - - - -
EHFOKGKC_00020 1.07e-93 yvaD - - S - - - Family of unknown function (DUF5360)
EHFOKGKC_00021 6.77e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EHFOKGKC_00022 5.17e-180 ydbA - - P - - - EcsC protein family
EHFOKGKC_00023 6.55e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
EHFOKGKC_00024 9.34e-85 ydbB - - G - - - Cupin domain
EHFOKGKC_00025 1.44e-79 ydbC - - S - - - Domain of unknown function (DUF4937
EHFOKGKC_00026 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
EHFOKGKC_00027 6.33e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EHFOKGKC_00028 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHFOKGKC_00029 2.13e-152 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHFOKGKC_00030 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHFOKGKC_00031 8.61e-231 ydbI - - S - - - AI-2E family transporter
EHFOKGKC_00032 4.79e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_00033 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHFOKGKC_00034 2.29e-70 ydbL - - - - - - -
EHFOKGKC_00035 7.51e-262 ydbM - - I - - - acyl-CoA dehydrogenase
EHFOKGKC_00036 1.13e-15 - - - S - - - Fur-regulated basic protein B
EHFOKGKC_00037 1.33e-13 - - - S - - - Fur-regulated basic protein A
EHFOKGKC_00038 2e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHFOKGKC_00039 2.25e-74 ydbP - - CO - - - Thioredoxin
EHFOKGKC_00040 6.19e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EHFOKGKC_00041 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EHFOKGKC_00042 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EHFOKGKC_00043 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EHFOKGKC_00044 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EHFOKGKC_00045 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EHFOKGKC_00046 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EHFOKGKC_00047 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EHFOKGKC_00048 4.17e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHFOKGKC_00049 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EHFOKGKC_00050 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EHFOKGKC_00051 1.43e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EHFOKGKC_00052 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EHFOKGKC_00053 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EHFOKGKC_00054 3.6e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EHFOKGKC_00055 2.8e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EHFOKGKC_00056 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EHFOKGKC_00057 6.56e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_00058 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EHFOKGKC_00059 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EHFOKGKC_00060 1.78e-21 - - - - - - - -
EHFOKGKC_00061 1.49e-76 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EHFOKGKC_00069 3.82e-194 yddH - - M - - - Lysozyme-like
EHFOKGKC_00070 2.14e-79 - - - K - - - Helix-turn-helix XRE-family like proteins
EHFOKGKC_00071 2.03e-63 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHFOKGKC_00072 8.63e-60 - - - - - - - -
EHFOKGKC_00073 1.79e-173 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHFOKGKC_00074 1.35e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EHFOKGKC_00075 1.11e-96 - - - S - - - SnoaL-like polyketide cyclase
EHFOKGKC_00076 1.81e-180 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
EHFOKGKC_00077 2.73e-92 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
EHFOKGKC_00078 1.13e-193 - - - S - - - Serine aminopeptidase, S33
EHFOKGKC_00079 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
EHFOKGKC_00080 2.04e-110 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EHFOKGKC_00081 1.28e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EHFOKGKC_00082 9.56e-82 - - - S - - - YjbR
EHFOKGKC_00083 1.66e-96 ywnA - - K - - - Transcriptional regulator
EHFOKGKC_00084 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EHFOKGKC_00086 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EHFOKGKC_00087 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EHFOKGKC_00088 1.14e-153 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EHFOKGKC_00089 3.77e-127 - - - S - - - Protein of unknown function (DUF2812)
EHFOKGKC_00090 8.2e-68 - - - K - - - Transcriptional regulator PadR-like family
EHFOKGKC_00091 4.85e-232 - - - S - - - Patatin-like phospholipase
EHFOKGKC_00092 2.47e-101 - - - S - - - DinB superfamily
EHFOKGKC_00093 1.49e-84 - - - G - - - Cupin domain
EHFOKGKC_00096 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EHFOKGKC_00097 5.33e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EHFOKGKC_00098 2.89e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EHFOKGKC_00100 2.92e-190 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
EHFOKGKC_00102 1.44e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EHFOKGKC_00103 1.51e-73 ydeH - - - - - - -
EHFOKGKC_00104 9.1e-111 - - - F - - - nucleoside 2-deoxyribosyltransferase
EHFOKGKC_00105 3.78e-248 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHFOKGKC_00106 4.34e-189 - - - Q - - - ubiE/COQ5 methyltransferase family
EHFOKGKC_00107 1.1e-192 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHFOKGKC_00108 1.98e-297 - - - G - - - Haloacid dehalogenase-like hydrolase
EHFOKGKC_00109 3.99e-210 - - - S - - - Sodium Bile acid symporter family
EHFOKGKC_00110 5.46e-259 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EHFOKGKC_00111 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EHFOKGKC_00112 1.94e-288 nhaC_1 - - C - - - antiporter
EHFOKGKC_00113 2.22e-96 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EHFOKGKC_00114 6.16e-213 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EHFOKGKC_00115 1.46e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_00117 1.62e-245 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EHFOKGKC_00118 2.43e-132 ydeS - - K - - - Transcriptional regulator
EHFOKGKC_00119 7.47e-202 ydeK - - EG - - - -transporter
EHFOKGKC_00120 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHFOKGKC_00121 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
EHFOKGKC_00122 3.42e-33 yraE - - - ko:K06440 - ko00000 -
EHFOKGKC_00123 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHFOKGKC_00124 4.76e-84 yraF - - M - - - Spore coat protein
EHFOKGKC_00125 4.19e-50 yraG - - - ko:K06440 - ko00000 -
EHFOKGKC_00126 7.63e-279 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00127 6.89e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_00128 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EHFOKGKC_00129 1.97e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
EHFOKGKC_00130 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EHFOKGKC_00131 6.17e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
EHFOKGKC_00132 1.6e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_00133 2.68e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EHFOKGKC_00134 8.22e-270 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EHFOKGKC_00135 3.76e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHFOKGKC_00136 1.84e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
EHFOKGKC_00137 5.2e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EHFOKGKC_00138 1.99e-104 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EHFOKGKC_00139 4.83e-15 bltR - - K - - - helix_turn_helix, mercury resistance
EHFOKGKC_00140 2.73e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EHFOKGKC_00141 6.64e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
EHFOKGKC_00142 6.25e-107 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EHFOKGKC_00145 3.43e-62 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EHFOKGKC_00146 1.09e-152 ydhC - - K - - - FCD
EHFOKGKC_00147 1.6e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHFOKGKC_00150 0.0 pbpE - - V - - - Beta-lactamase
EHFOKGKC_00152 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
EHFOKGKC_00153 3.18e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EHFOKGKC_00154 2.06e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EHFOKGKC_00155 6.29e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
EHFOKGKC_00156 5.85e-275 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EHFOKGKC_00157 4.25e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EHFOKGKC_00158 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHFOKGKC_00159 1.72e-134 yvdT_1 - - K - - - Transcriptional regulator
EHFOKGKC_00160 0.0 ybeC - - E - - - amino acid
EHFOKGKC_00161 7.31e-213 ydhU - - P ko:K07217 - ko00000 Catalase
EHFOKGKC_00162 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EHFOKGKC_00163 2.23e-234 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EHFOKGKC_00164 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHFOKGKC_00167 3.76e-247 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EHFOKGKC_00168 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHFOKGKC_00169 3.71e-62 yutD - - S - - - protein conserved in bacteria
EHFOKGKC_00170 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
EHFOKGKC_00171 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EHFOKGKC_00172 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EHFOKGKC_00173 1.55e-250 yutH - - S - - - Spore coat protein
EHFOKGKC_00174 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EHFOKGKC_00175 2.3e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHFOKGKC_00176 2.26e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EHFOKGKC_00177 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EHFOKGKC_00178 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EHFOKGKC_00179 3.29e-73 yuzD - - S - - - protein conserved in bacteria
EHFOKGKC_00180 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHFOKGKC_00181 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EHFOKGKC_00182 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHFOKGKC_00183 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHFOKGKC_00184 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EHFOKGKC_00185 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00186 7.08e-123 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EHFOKGKC_00188 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
EHFOKGKC_00190 2.28e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHFOKGKC_00191 5.92e-93 - - - CP - - - Membrane
EHFOKGKC_00192 5.68e-40 - - - - - - - -
EHFOKGKC_00193 5.49e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHFOKGKC_00195 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EHFOKGKC_00196 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHFOKGKC_00197 8.54e-46 yuiB - - S - - - Putative membrane protein
EHFOKGKC_00198 7.98e-150 yuiC - - S - - - protein conserved in bacteria
EHFOKGKC_00199 4.99e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EHFOKGKC_00200 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHFOKGKC_00201 2.86e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EHFOKGKC_00202 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EHFOKGKC_00203 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EHFOKGKC_00204 1.26e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
EHFOKGKC_00205 1.49e-172 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00206 4.55e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHFOKGKC_00207 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EHFOKGKC_00208 3.37e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EHFOKGKC_00209 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_00210 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EHFOKGKC_00211 3.58e-170 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EHFOKGKC_00212 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EHFOKGKC_00213 5.19e-292 yukF - - QT - - - Transcriptional regulator
EHFOKGKC_00214 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
EHFOKGKC_00215 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EHFOKGKC_00216 7.95e-276 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EHFOKGKC_00217 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EHFOKGKC_00218 0.0 yueB - - S - - - type VII secretion protein EsaA
EHFOKGKC_00219 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
EHFOKGKC_00220 4.81e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_00221 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EHFOKGKC_00222 5.68e-31 - - - S - - - Protein of unknown function (DUF2642)
EHFOKGKC_00223 1.88e-238 yueF - - S - - - transporter activity
EHFOKGKC_00224 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EHFOKGKC_00225 5.46e-51 yueH - - S - - - YueH-like protein
EHFOKGKC_00226 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
EHFOKGKC_00227 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EHFOKGKC_00228 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHFOKGKC_00229 3.71e-245 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EHFOKGKC_00230 2.61e-296 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00231 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_00232 3.42e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EHFOKGKC_00233 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EHFOKGKC_00234 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHFOKGKC_00235 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHFOKGKC_00236 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHFOKGKC_00237 6.01e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHFOKGKC_00238 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHFOKGKC_00239 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EHFOKGKC_00241 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHFOKGKC_00242 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHFOKGKC_00243 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_00244 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EHFOKGKC_00245 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHFOKGKC_00246 4.21e-315 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHFOKGKC_00247 4.05e-29 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHFOKGKC_00248 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
EHFOKGKC_00249 2.62e-95 yuxK - - S - - - protein conserved in bacteria
EHFOKGKC_00250 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EHFOKGKC_00251 2.48e-245 yuxJ - - EGP - - - Major facilitator superfamily
EHFOKGKC_00252 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EHFOKGKC_00253 1.62e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EHFOKGKC_00254 1.81e-292 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00255 2.73e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EHFOKGKC_00256 1.22e-54 yugE - - S - - - Domain of unknown function (DUF1871)
EHFOKGKC_00257 4.03e-200 yugF - - I - - - Hydrolase
EHFOKGKC_00258 3.75e-109 alaR - - K - - - Transcriptional regulator
EHFOKGKC_00259 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EHFOKGKC_00260 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHFOKGKC_00261 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EHFOKGKC_00262 1.65e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EHFOKGKC_00263 6.49e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EHFOKGKC_00264 4.34e-152 ycaC - - Q - - - Isochorismatase family
EHFOKGKC_00265 1.95e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
EHFOKGKC_00266 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EHFOKGKC_00268 3.48e-94 yugN - - S - - - YugN-like family
EHFOKGKC_00269 9.77e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EHFOKGKC_00270 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
EHFOKGKC_00271 4.35e-23 - - - - - - - -
EHFOKGKC_00272 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EHFOKGKC_00273 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHFOKGKC_00274 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHFOKGKC_00275 1.89e-98 yugU - - S - - - Uncharacterised protein family UPF0047
EHFOKGKC_00276 3.47e-243 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EHFOKGKC_00277 9.36e-55 - - - - - - - -
EHFOKGKC_00278 9.03e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EHFOKGKC_00279 4.4e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHFOKGKC_00280 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHFOKGKC_00281 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHFOKGKC_00282 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHFOKGKC_00283 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EHFOKGKC_00284 7.8e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHFOKGKC_00285 9.96e-251 yubA - - S - - - transporter activity
EHFOKGKC_00286 1.88e-186 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EHFOKGKC_00288 4.84e-52 - - - - - - - -
EHFOKGKC_00289 2.11e-19 - - - - - - - -
EHFOKGKC_00290 9.76e-14 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EHFOKGKC_00291 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EHFOKGKC_00292 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHFOKGKC_00293 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHFOKGKC_00294 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EHFOKGKC_00295 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
EHFOKGKC_00296 3.55e-133 ypbE - - M - - - Lysin motif
EHFOKGKC_00297 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EHFOKGKC_00298 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHFOKGKC_00299 1.05e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EHFOKGKC_00300 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EHFOKGKC_00301 6.2e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EHFOKGKC_00302 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHFOKGKC_00303 4.07e-249 rsiX - - - - - - -
EHFOKGKC_00304 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_00305 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00306 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_00307 1.26e-251 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EHFOKGKC_00308 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EHFOKGKC_00309 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EHFOKGKC_00310 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHFOKGKC_00311 3.66e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EHFOKGKC_00312 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EHFOKGKC_00313 9.35e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHFOKGKC_00314 5.05e-121 ypuI - - S - - - Protein of unknown function (DUF3907)
EHFOKGKC_00315 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHFOKGKC_00316 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHFOKGKC_00318 5.71e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EHFOKGKC_00319 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHFOKGKC_00320 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EHFOKGKC_00321 1.48e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHFOKGKC_00322 2.2e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EHFOKGKC_00323 5.34e-268 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHFOKGKC_00324 4.92e-71 ypuD - - - - - - -
EHFOKGKC_00325 3.8e-130 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHFOKGKC_00326 9.6e-106 ccdC1 - - O - - - Protein of unknown function (DUF1453)
EHFOKGKC_00327 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHFOKGKC_00328 6.31e-199 ypuA - - S - - - Secreted protein
EHFOKGKC_00329 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EHFOKGKC_00330 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EHFOKGKC_00331 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
EHFOKGKC_00332 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EHFOKGKC_00333 5.77e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EHFOKGKC_00334 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EHFOKGKC_00335 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EHFOKGKC_00336 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_00337 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EHFOKGKC_00338 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EHFOKGKC_00339 1.74e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHFOKGKC_00340 9.06e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHFOKGKC_00341 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHFOKGKC_00342 2.17e-211 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EHFOKGKC_00343 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
EHFOKGKC_00344 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EHFOKGKC_00345 2.04e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EHFOKGKC_00346 1.93e-38 yqkK - - - - - - -
EHFOKGKC_00347 1.96e-30 - - - - - - - -
EHFOKGKC_00348 8.31e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHFOKGKC_00349 5.89e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHFOKGKC_00350 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EHFOKGKC_00351 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EHFOKGKC_00352 1.15e-75 ansR - - K - - - Transcriptional regulator
EHFOKGKC_00353 1.19e-279 yqxK - - L - - - DNA helicase
EHFOKGKC_00354 4.25e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EHFOKGKC_00355 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
EHFOKGKC_00356 1.47e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EHFOKGKC_00357 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
EHFOKGKC_00358 9.23e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHFOKGKC_00359 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
EHFOKGKC_00360 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
EHFOKGKC_00361 1.44e-223 yqkA - - K - - - GrpB protein
EHFOKGKC_00362 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EHFOKGKC_00363 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EHFOKGKC_00364 1.9e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHFOKGKC_00365 9.19e-76 - - - S - - - YolD-like protein
EHFOKGKC_00367 8.33e-238 yueF - - S - - - transporter activity
EHFOKGKC_00369 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHFOKGKC_00370 4.46e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EHFOKGKC_00371 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EHFOKGKC_00372 3.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00373 1.32e-221 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHFOKGKC_00374 8.27e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHFOKGKC_00375 6.86e-175 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EHFOKGKC_00376 3.9e-306 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EHFOKGKC_00377 4.87e-282 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHFOKGKC_00378 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHFOKGKC_00379 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00380 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00381 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00382 8.82e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EHFOKGKC_00383 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EHFOKGKC_00384 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EHFOKGKC_00385 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHFOKGKC_00386 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EHFOKGKC_00387 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHFOKGKC_00388 8.16e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EHFOKGKC_00389 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EHFOKGKC_00390 3.49e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHFOKGKC_00391 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
EHFOKGKC_00392 6.57e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHFOKGKC_00393 4.13e-109 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EHFOKGKC_00394 9.42e-314 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EHFOKGKC_00395 3.84e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHFOKGKC_00396 6.78e-46 ylaI - - S - - - protein conserved in bacteria
EHFOKGKC_00397 2.44e-65 - - - S - - - YlaH-like protein
EHFOKGKC_00398 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EHFOKGKC_00399 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
EHFOKGKC_00400 1.39e-52 ylaE - - - - - - -
EHFOKGKC_00402 4.7e-120 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_00403 7.37e-59 ylaB - - - - - - -
EHFOKGKC_00404 3.93e-234 ylaA - - - - - - -
EHFOKGKC_00405 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EHFOKGKC_00406 7.56e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
EHFOKGKC_00407 8.12e-196 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EHFOKGKC_00408 7.89e-32 ykzI - - - - - - -
EHFOKGKC_00409 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
EHFOKGKC_00410 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
EHFOKGKC_00411 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EHFOKGKC_00412 5.69e-192 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHFOKGKC_00413 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EHFOKGKC_00414 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHFOKGKC_00415 2.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHFOKGKC_00416 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHFOKGKC_00417 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHFOKGKC_00418 3.33e-267 - - - V - - - Beta-lactamase
EHFOKGKC_00419 0.0 - - - IQ - - - Phosphopantetheine attachment site
EHFOKGKC_00420 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00421 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00422 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00423 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00424 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
EHFOKGKC_00425 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_00426 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_00427 5.6e-134 ykyA - - L - - - Putative cell-wall binding lipoprotein
EHFOKGKC_00428 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHFOKGKC_00429 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHFOKGKC_00430 3.05e-187 ykrA - - S - - - hydrolases of the HAD superfamily
EHFOKGKC_00431 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
EHFOKGKC_00432 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHFOKGKC_00433 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
EHFOKGKC_00434 3.82e-39 ypeQ - - S - - - Zinc-finger
EHFOKGKC_00435 5.91e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EHFOKGKC_00436 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHFOKGKC_00437 1.74e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EHFOKGKC_00439 3.19e-208 ypcP - - L - - - 5'3' exonuclease
EHFOKGKC_00440 2.44e-10 - - - - - - - -
EHFOKGKC_00441 2.02e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
EHFOKGKC_00442 0.0 ypbR - - S - - - Dynamin family
EHFOKGKC_00443 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EHFOKGKC_00444 1.79e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EHFOKGKC_00445 3.29e-136 - - - J - - - Acetyltransferase (GNAT) domain
EHFOKGKC_00446 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
EHFOKGKC_00447 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
EHFOKGKC_00448 6.28e-130 yrdC - - Q - - - Isochorismatase family
EHFOKGKC_00449 3.16e-07 - - - S - - - Bacillus cereus group antimicrobial protein
EHFOKGKC_00450 1.45e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
EHFOKGKC_00451 1.16e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EHFOKGKC_00452 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHFOKGKC_00453 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EHFOKGKC_00455 6.91e-31 - - - S - - - YpzG-like protein
EHFOKGKC_00456 2.32e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EHFOKGKC_00457 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EHFOKGKC_00458 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
EHFOKGKC_00459 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
EHFOKGKC_00461 1.83e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EHFOKGKC_00462 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EHFOKGKC_00463 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EHFOKGKC_00464 5.09e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHFOKGKC_00465 1.72e-83 yppG - - S - - - YppG-like protein
EHFOKGKC_00469 0.000542 - - - - ko:K06430 - ko00000 -
EHFOKGKC_00470 3.32e-238 yppC - - S - - - Protein of unknown function (DUF2515)
EHFOKGKC_00471 1.47e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EHFOKGKC_00472 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHFOKGKC_00473 8.6e-118 ypoC - - - - - - -
EHFOKGKC_00474 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHFOKGKC_00475 3.99e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EHFOKGKC_00476 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EHFOKGKC_00477 4.19e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHFOKGKC_00478 9.65e-105 ypmB - - S - - - protein conserved in bacteria
EHFOKGKC_00479 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EHFOKGKC_00480 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EHFOKGKC_00481 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EHFOKGKC_00482 5.71e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHFOKGKC_00483 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EHFOKGKC_00484 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EHFOKGKC_00485 1.98e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EHFOKGKC_00486 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EHFOKGKC_00487 1.23e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EHFOKGKC_00488 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EHFOKGKC_00489 1.39e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EHFOKGKC_00490 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EHFOKGKC_00491 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_00492 1.42e-289 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHFOKGKC_00493 2.05e-182 ypjB - - S - - - sporulation protein
EHFOKGKC_00494 9.19e-137 ypjA - - S - - - membrane
EHFOKGKC_00495 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EHFOKGKC_00496 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EHFOKGKC_00497 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EHFOKGKC_00498 5.77e-102 ypiF - - S - - - Protein of unknown function (DUF2487)
EHFOKGKC_00499 1.06e-128 ypiB - - S - - - Belongs to the UPF0302 family
EHFOKGKC_00500 7.49e-299 ypiA - - S - - - COG0457 FOG TPR repeat
EHFOKGKC_00501 5.73e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EHFOKGKC_00502 1.45e-259 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EHFOKGKC_00503 2.14e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHFOKGKC_00504 1.62e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EHFOKGKC_00505 6.04e-291 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EHFOKGKC_00506 9.06e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EHFOKGKC_00507 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EHFOKGKC_00508 2.03e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHFOKGKC_00509 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHFOKGKC_00510 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EHFOKGKC_00511 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHFOKGKC_00512 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHFOKGKC_00513 2.05e-180 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EHFOKGKC_00514 2.35e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EHFOKGKC_00515 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHFOKGKC_00516 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EHFOKGKC_00517 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EHFOKGKC_00518 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EHFOKGKC_00519 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EHFOKGKC_00520 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHFOKGKC_00521 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EHFOKGKC_00522 3.97e-172 yphF - - - - - - -
EHFOKGKC_00523 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
EHFOKGKC_00524 8.18e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EHFOKGKC_00525 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EHFOKGKC_00526 8.79e-136 yphA - - - - - - -
EHFOKGKC_00527 1.87e-12 - - - S - - - YpzI-like protein
EHFOKGKC_00528 3.28e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EHFOKGKC_00529 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EHFOKGKC_00530 2.87e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EHFOKGKC_00531 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
EHFOKGKC_00532 3.35e-06 ypfA - - M - - - glycosyltransferase
EHFOKGKC_00533 5.02e-31 ypfA - - M - - - Flagellar protein YcgR
EHFOKGKC_00534 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EHFOKGKC_00535 2.54e-211 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EHFOKGKC_00536 1.28e-131 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EHFOKGKC_00539 4.51e-127 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
EHFOKGKC_00540 2.03e-109 yokK - - S - - - SMI1 / KNR4 family
EHFOKGKC_00541 1.9e-35 - - - S - - - Acetyltransferase (GNAT) domain
EHFOKGKC_00543 2.56e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHFOKGKC_00544 3.89e-101 yoqH - - M - - - LysM domain
EHFOKGKC_00549 1.32e-101 - - - - - - - -
EHFOKGKC_00555 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHFOKGKC_00556 9.09e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EHFOKGKC_00557 1.56e-231 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EHFOKGKC_00558 1.55e-90 cgeA - - - ko:K06319 - ko00000 -
EHFOKGKC_00559 3.32e-62 cgeC - - - ko:K06321 - ko00000 -
EHFOKGKC_00560 1.97e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EHFOKGKC_00561 4.02e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EHFOKGKC_00563 2.39e-83 - - - L - - - Bacterial transcription activator, effector binding domain
EHFOKGKC_00564 1.19e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHFOKGKC_00565 6.87e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHFOKGKC_00566 2.68e-159 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHFOKGKC_00567 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EHFOKGKC_00568 1.99e-203 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EHFOKGKC_00569 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EHFOKGKC_00570 2.42e-63 yokU - - S - - - YokU-like protein, putative antitoxin
EHFOKGKC_00571 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
EHFOKGKC_00572 1.9e-161 yodN - - - - - - -
EHFOKGKC_00574 9.77e-34 yozD - - S - - - YozD-like protein
EHFOKGKC_00575 2.23e-135 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EHFOKGKC_00576 1.16e-72 yodL - - S - - - YodL-like
EHFOKGKC_00578 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EHFOKGKC_00579 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EHFOKGKC_00580 6.87e-50 yodI - - - - - - -
EHFOKGKC_00581 1.76e-165 yodH - - Q - - - Methyltransferase
EHFOKGKC_00582 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHFOKGKC_00583 1.23e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_00584 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHFOKGKC_00585 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
EHFOKGKC_00586 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHFOKGKC_00587 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
EHFOKGKC_00588 1.8e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHFOKGKC_00589 4.37e-143 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EHFOKGKC_00590 1.35e-138 yodC - - C - - - nitroreductase
EHFOKGKC_00591 2e-73 yodB - - K - - - transcriptional
EHFOKGKC_00592 1.08e-89 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EHFOKGKC_00593 2.59e-89 iolK - - S - - - tautomerase
EHFOKGKC_00595 1.15e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EHFOKGKC_00596 8.49e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EHFOKGKC_00597 1.05e-30 - - - - - - - -
EHFOKGKC_00598 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EHFOKGKC_00599 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EHFOKGKC_00600 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHFOKGKC_00601 8e-309 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EHFOKGKC_00603 9.47e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHFOKGKC_00604 7.02e-287 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EHFOKGKC_00605 2.12e-291 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHFOKGKC_00606 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHFOKGKC_00607 3.45e-208 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EHFOKGKC_00608 0.0 yojO - - P - - - Von Willebrand factor
EHFOKGKC_00609 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EHFOKGKC_00610 2.47e-261 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EHFOKGKC_00611 5.46e-181 - - - S - - - Metallo-beta-lactamase superfamily
EHFOKGKC_00612 2.82e-214 yocS - - S ko:K03453 - ko00000 -transporter
EHFOKGKC_00613 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHFOKGKC_00614 4.76e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EHFOKGKC_00615 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EHFOKGKC_00616 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHFOKGKC_00617 4.69e-43 yozC - - - - - - -
EHFOKGKC_00619 5.32e-75 yozO - - S - - - Bacterial PH domain
EHFOKGKC_00620 6.36e-50 yocN - - - - - - -
EHFOKGKC_00621 5.58e-59 yozN - - - - - - -
EHFOKGKC_00622 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHFOKGKC_00623 3.51e-13 yocN - - - - - - -
EHFOKGKC_00624 2.71e-13 yocL - - - - - - -
EHFOKGKC_00625 4.5e-79 yocK - - T - - - general stress protein
EHFOKGKC_00627 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHFOKGKC_00628 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHFOKGKC_00629 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
EHFOKGKC_00631 1.77e-236 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EHFOKGKC_00632 1.6e-123 yocC - - - - - - -
EHFOKGKC_00633 4.46e-182 - - - J - - - Protein required for attachment to host cells
EHFOKGKC_00634 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
EHFOKGKC_00635 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHFOKGKC_00636 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EHFOKGKC_00637 2.72e-119 yobW - - - - - - -
EHFOKGKC_00638 1.1e-171 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHFOKGKC_00639 1.86e-122 yobS - - K - - - Transcriptional regulator
EHFOKGKC_00640 3.17e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EHFOKGKC_00641 2.12e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EHFOKGKC_00642 6.38e-81 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
EHFOKGKC_00643 3.41e-88 yvrL - - S - - - Regulatory protein YrvL
EHFOKGKC_00644 8.91e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHFOKGKC_00645 1.88e-21 - - - S - - - YvrJ protein family
EHFOKGKC_00646 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EHFOKGKC_00647 1.67e-50 - - - - - - - -
EHFOKGKC_00648 7.74e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_00649 0.0 yvrG - - T - - - Histidine kinase
EHFOKGKC_00650 1.09e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EHFOKGKC_00651 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00652 9.14e-213 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHFOKGKC_00653 7.3e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_00654 1.04e-286 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EHFOKGKC_00655 3.1e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EHFOKGKC_00656 5.58e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_00657 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EHFOKGKC_00658 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EHFOKGKC_00659 8.26e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EHFOKGKC_00660 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EHFOKGKC_00661 9.98e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00662 1.02e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_00663 7.85e-265 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EHFOKGKC_00664 2.52e-243 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHFOKGKC_00665 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHFOKGKC_00666 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
EHFOKGKC_00667 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EHFOKGKC_00668 3.11e-201 yuxN - - K - - - Transcriptional regulator
EHFOKGKC_00669 4.63e-33 - - - - - - - -
EHFOKGKC_00670 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_00671 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_00672 3.38e-308 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHFOKGKC_00673 4.12e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EHFOKGKC_00674 1.34e-197 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00675 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EHFOKGKC_00676 2.66e-60 - - - S - - - YusW-like protein
EHFOKGKC_00677 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHFOKGKC_00678 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
EHFOKGKC_00679 8.47e-241 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHFOKGKC_00680 1.68e-175 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
EHFOKGKC_00681 8.78e-206 - - - K - - - Transcriptional regulator
EHFOKGKC_00682 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EHFOKGKC_00683 5.19e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00684 1.69e-86 yusQ - - S - - - Tautomerase enzyme
EHFOKGKC_00685 0.0 yusP - - P - - - Major facilitator superfamily
EHFOKGKC_00686 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EHFOKGKC_00687 4.46e-72 yusN - - M - - - Coat F domain
EHFOKGKC_00688 3.2e-58 - - - - - - - -
EHFOKGKC_00689 7.8e-264 yusP - - P - - - Major facilitator superfamily
EHFOKGKC_00690 1.31e-215 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHFOKGKC_00691 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EHFOKGKC_00692 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EHFOKGKC_00693 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHFOKGKC_00694 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EHFOKGKC_00695 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EHFOKGKC_00696 1.8e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EHFOKGKC_00697 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EHFOKGKC_00698 1.64e-72 yusE - - CO - - - Thioredoxin
EHFOKGKC_00699 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
EHFOKGKC_00700 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHFOKGKC_00701 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EHFOKGKC_00702 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EHFOKGKC_00703 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHFOKGKC_00704 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EHFOKGKC_00705 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EHFOKGKC_00706 3.14e-296 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHFOKGKC_00707 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EHFOKGKC_00708 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EHFOKGKC_00709 3.58e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EHFOKGKC_00710 2.82e-100 yncE - - S - - - Protein of unknown function (DUF2691)
EHFOKGKC_00711 1.79e-164 - - - Q - - - ubiE/COQ5 methyltransferase family
EHFOKGKC_00712 8.71e-258 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EHFOKGKC_00713 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EHFOKGKC_00716 3.88e-211 - - - K - - - helix_turn_helix, mercury resistance
EHFOKGKC_00717 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EHFOKGKC_00718 1.49e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EHFOKGKC_00719 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHFOKGKC_00720 1.47e-208 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EHFOKGKC_00721 2.63e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EHFOKGKC_00722 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EHFOKGKC_00723 7.84e-264 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_00724 7.06e-218 bsn - - L - - - Ribonuclease
EHFOKGKC_00725 1.77e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EHFOKGKC_00726 5.95e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EHFOKGKC_00727 3.01e-274 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_00728 5.84e-83 - - - - - - - -
EHFOKGKC_00730 8.86e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EHFOKGKC_00731 2.6e-101 ydaG - - S - - - general stress protein
EHFOKGKC_00732 4.71e-148 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHFOKGKC_00733 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EHFOKGKC_00734 3.82e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_00735 0.0 ydaB - - IQ - - - acyl-CoA ligase
EHFOKGKC_00736 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EHFOKGKC_00737 1.05e-220 ycsN - - S - - - Oxidoreductase
EHFOKGKC_00738 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EHFOKGKC_00739 9.52e-72 yczJ - - S - - - biosynthesis
EHFOKGKC_00741 9.09e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EHFOKGKC_00742 9.38e-167 kipR - - K - - - Transcriptional regulator
EHFOKGKC_00743 4.7e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EHFOKGKC_00744 1.98e-176 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EHFOKGKC_00745 2.41e-192 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EHFOKGKC_00746 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EHFOKGKC_00747 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EHFOKGKC_00748 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHFOKGKC_00750 8.28e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EHFOKGKC_00751 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EHFOKGKC_00752 1.38e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EHFOKGKC_00753 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EHFOKGKC_00754 9.6e-73 - - - - - - - -
EHFOKGKC_00755 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHFOKGKC_00756 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EHFOKGKC_00757 1.39e-129 ycnI - - S - - - protein conserved in bacteria
EHFOKGKC_00758 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_00759 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EHFOKGKC_00760 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHFOKGKC_00761 7.59e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHFOKGKC_00762 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHFOKGKC_00763 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHFOKGKC_00764 1.97e-59 ycnE - - S - - - Monooxygenase
EHFOKGKC_00765 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
EHFOKGKC_00766 1.23e-194 ycnC - - K - - - Transcriptional regulator
EHFOKGKC_00767 9.81e-314 ycnB - - EGP - - - the major facilitator superfamily
EHFOKGKC_00768 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EHFOKGKC_00769 3.8e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_00770 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_00771 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_00772 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHFOKGKC_00774 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHFOKGKC_00775 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
EHFOKGKC_00776 2.6e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_00777 3.67e-311 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EHFOKGKC_00778 1.01e-152 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EHFOKGKC_00779 0.0 yxeQ - - S - - - MmgE/PrpD family
EHFOKGKC_00780 4.14e-278 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EHFOKGKC_00781 9.29e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_00782 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHFOKGKC_00783 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHFOKGKC_00784 3.64e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHFOKGKC_00785 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_00786 9.23e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EHFOKGKC_00787 5.93e-302 gerKC - - S ko:K06297 - ko00000 spore germination
EHFOKGKC_00788 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EHFOKGKC_00790 0.0 yclG - - M - - - Pectate lyase superfamily protein
EHFOKGKC_00791 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EHFOKGKC_00792 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EHFOKGKC_00793 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EHFOKGKC_00794 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EHFOKGKC_00795 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EHFOKGKC_00796 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHFOKGKC_00797 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EHFOKGKC_00798 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EHFOKGKC_00799 1.23e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EHFOKGKC_00800 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EHFOKGKC_00801 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHFOKGKC_00802 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EHFOKGKC_00803 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EHFOKGKC_00804 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EHFOKGKC_00805 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHFOKGKC_00806 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EHFOKGKC_00807 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EHFOKGKC_00808 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EHFOKGKC_00809 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHFOKGKC_00810 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHFOKGKC_00811 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EHFOKGKC_00812 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHFOKGKC_00813 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EHFOKGKC_00814 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EHFOKGKC_00815 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHFOKGKC_00816 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHFOKGKC_00817 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EHFOKGKC_00818 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHFOKGKC_00819 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EHFOKGKC_00820 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHFOKGKC_00821 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHFOKGKC_00822 3.32e-239 ybaC - - S - - - Alpha/beta hydrolase family
EHFOKGKC_00823 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EHFOKGKC_00824 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHFOKGKC_00825 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EHFOKGKC_00826 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EHFOKGKC_00827 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHFOKGKC_00828 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHFOKGKC_00829 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHFOKGKC_00830 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHFOKGKC_00831 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHFOKGKC_00832 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EHFOKGKC_00833 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHFOKGKC_00834 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHFOKGKC_00835 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHFOKGKC_00836 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHFOKGKC_00837 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHFOKGKC_00838 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHFOKGKC_00839 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHFOKGKC_00840 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHFOKGKC_00841 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHFOKGKC_00842 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EHFOKGKC_00843 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHFOKGKC_00844 7.75e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EHFOKGKC_00845 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EHFOKGKC_00846 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHFOKGKC_00847 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHFOKGKC_00848 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EHFOKGKC_00849 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHFOKGKC_00850 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHFOKGKC_00851 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHFOKGKC_00852 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EHFOKGKC_00853 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHFOKGKC_00854 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHFOKGKC_00855 1.13e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHFOKGKC_00856 8.74e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EHFOKGKC_00857 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHFOKGKC_00858 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EHFOKGKC_00859 7.18e-185 ybaJ - - Q - - - Methyltransferase domain
EHFOKGKC_00860 1.06e-106 yizA - - S - - - Damage-inducible protein DinB
EHFOKGKC_00861 1.08e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
EHFOKGKC_00862 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHFOKGKC_00863 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EHFOKGKC_00864 6.81e-103 gerD - - - ko:K06294 - ko00000 -
EHFOKGKC_00865 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EHFOKGKC_00866 9.06e-183 pdaB - - G - - - Polysaccharide deacetylase
EHFOKGKC_00867 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EHFOKGKC_00868 2.17e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHFOKGKC_00869 6.1e-40 yazB - - K - - - transcriptional
EHFOKGKC_00870 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHFOKGKC_00871 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHFOKGKC_00872 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHFOKGKC_00873 5.97e-208 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EHFOKGKC_00874 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EHFOKGKC_00875 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHFOKGKC_00876 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHFOKGKC_00877 1.02e-200 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EHFOKGKC_00878 1.85e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHFOKGKC_00879 6.64e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHFOKGKC_00880 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHFOKGKC_00881 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EHFOKGKC_00882 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EHFOKGKC_00883 1.34e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHFOKGKC_00884 2.19e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHFOKGKC_00885 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EHFOKGKC_00888 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHFOKGKC_00889 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EHFOKGKC_00890 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
EHFOKGKC_00891 5.47e-66 yabP - - S - - - Sporulation protein YabP
EHFOKGKC_00892 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EHFOKGKC_00893 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EHFOKGKC_00894 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_00895 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EHFOKGKC_00896 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHFOKGKC_00897 1.28e-53 yabK - - S - - - Peptide ABC transporter permease
EHFOKGKC_00898 7.09e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EHFOKGKC_00899 6.18e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHFOKGKC_00900 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHFOKGKC_00901 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHFOKGKC_00902 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EHFOKGKC_00903 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EHFOKGKC_00904 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EHFOKGKC_00905 5.51e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHFOKGKC_00906 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
EHFOKGKC_00907 5.32e-53 veg - - S - - - protein conserved in bacteria
EHFOKGKC_00908 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
EHFOKGKC_00909 8.41e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EHFOKGKC_00910 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EHFOKGKC_00911 2.49e-310 yabE - - T - - - protein conserved in bacteria
EHFOKGKC_00912 1.24e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EHFOKGKC_00913 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHFOKGKC_00914 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EHFOKGKC_00915 2.85e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHFOKGKC_00916 1.41e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EHFOKGKC_00917 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EHFOKGKC_00918 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EHFOKGKC_00919 9e-189 yaaT - - S - - - stage 0 sporulation protein
EHFOKGKC_00920 3.29e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EHFOKGKC_00921 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EHFOKGKC_00922 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
EHFOKGKC_00923 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHFOKGKC_00924 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EHFOKGKC_00925 5.11e-246 yaaN - - P - - - Belongs to the TelA family
EHFOKGKC_00926 6.9e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EHFOKGKC_00927 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EHFOKGKC_00928 1.14e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHFOKGKC_00929 1.37e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_00930 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_00931 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHFOKGKC_00932 3.4e-157 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHFOKGKC_00933 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EHFOKGKC_00934 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EHFOKGKC_00935 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EHFOKGKC_00936 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EHFOKGKC_00937 4.72e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EHFOKGKC_00938 6.26e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EHFOKGKC_00939 2.33e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EHFOKGKC_00940 6.87e-145 yfiK - - K - - - Regulator
EHFOKGKC_00941 1.17e-250 - - - T - - - Histidine kinase
EHFOKGKC_00942 1.42e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EHFOKGKC_00943 6.04e-250 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHFOKGKC_00944 2.94e-261 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EHFOKGKC_00945 1.77e-200 yvgN - - S - - - reductase
EHFOKGKC_00946 2.29e-112 yvgO - - - - - - -
EHFOKGKC_00947 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EHFOKGKC_00948 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EHFOKGKC_00949 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHFOKGKC_00950 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHFOKGKC_00951 6.36e-130 yvgT - - S - - - membrane
EHFOKGKC_00952 6.64e-191 - - - S - - - Metallo-peptidase family M12
EHFOKGKC_00953 3.56e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EHFOKGKC_00954 3.33e-140 bdbD - - O - - - Thioredoxin
EHFOKGKC_00955 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHFOKGKC_00956 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EHFOKGKC_00957 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
EHFOKGKC_00958 2.31e-63 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EHFOKGKC_00959 1.86e-244 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHFOKGKC_00960 5.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHFOKGKC_00961 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_00962 4.82e-60 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EHFOKGKC_00963 1.18e-230 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_00964 3.01e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHFOKGKC_00965 1.66e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHFOKGKC_00966 6.25e-158 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHFOKGKC_00967 1.5e-189 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHFOKGKC_00968 3.41e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHFOKGKC_00969 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHFOKGKC_00970 1.14e-205 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EHFOKGKC_00971 3.94e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_00972 1.43e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EHFOKGKC_00973 2.2e-51 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EHFOKGKC_00975 1.39e-106 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHFOKGKC_00976 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EHFOKGKC_00977 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EHFOKGKC_00978 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EHFOKGKC_00979 1.64e-47 yvzC - - K - - - transcriptional
EHFOKGKC_00980 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EHFOKGKC_00981 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EHFOKGKC_00982 2.97e-70 yvaP - - K - - - transcriptional
EHFOKGKC_00983 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
EHFOKGKC_00984 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
EHFOKGKC_00985 2.68e-176 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_00986 6.23e-160 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_00987 4.44e-161 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_00988 1.72e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHFOKGKC_00989 3.12e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHFOKGKC_00990 8e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHFOKGKC_00991 4.07e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHFOKGKC_00992 9.8e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHFOKGKC_00993 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHFOKGKC_00994 6.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHFOKGKC_00995 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHFOKGKC_00996 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHFOKGKC_00997 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHFOKGKC_00998 3.8e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EHFOKGKC_00999 2.66e-157 yvbI - - M - - - Membrane
EHFOKGKC_01000 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EHFOKGKC_01001 1.11e-106 yvbK - - K - - - acetyltransferase
EHFOKGKC_01002 1.81e-268 - - - EGP - - - Major facilitator Superfamily
EHFOKGKC_01003 1.62e-227 - - - - - - - -
EHFOKGKC_01004 7.75e-163 - - - S - - - GlcNAc-PI de-N-acetylase
EHFOKGKC_01005 1.37e-183 - - - C - - - WbqC-like protein family
EHFOKGKC_01006 6.49e-191 - - - M - - - Protein involved in cellulose biosynthesis
EHFOKGKC_01007 1.69e-297 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHFOKGKC_01008 2.99e-220 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
EHFOKGKC_01009 2.3e-276 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EHFOKGKC_01010 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHFOKGKC_01011 1.03e-304 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EHFOKGKC_01012 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EHFOKGKC_01013 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EHFOKGKC_01014 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EHFOKGKC_01015 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EHFOKGKC_01016 4.7e-237 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHFOKGKC_01017 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHFOKGKC_01019 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHFOKGKC_01020 3.31e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EHFOKGKC_01021 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_01023 5.04e-199 yvbU - - K - - - Transcriptional regulator
EHFOKGKC_01024 1.23e-201 yvbV - - EG - - - EamA-like transporter family
EHFOKGKC_01025 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_01026 0.0 - - - - - - - -
EHFOKGKC_01027 3.55e-231 yhjM - - K - - - Transcriptional regulator
EHFOKGKC_01028 3e-147 - - - S ko:K07149 - ko00000 Membrane
EHFOKGKC_01029 2.09e-213 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHFOKGKC_01030 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
EHFOKGKC_01031 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EHFOKGKC_01032 4.57e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EHFOKGKC_01033 1.23e-173 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHFOKGKC_01034 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EHFOKGKC_01035 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHFOKGKC_01036 1.85e-283 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHFOKGKC_01037 3.1e-156 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EHFOKGKC_01038 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EHFOKGKC_01039 6.55e-309 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EHFOKGKC_01040 4.01e-44 yvfG - - S - - - YvfG protein
EHFOKGKC_01041 8.14e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EHFOKGKC_01042 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EHFOKGKC_01043 5.73e-79 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHFOKGKC_01044 1.92e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHFOKGKC_01045 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_01046 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHFOKGKC_01047 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EHFOKGKC_01048 1.61e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHFOKGKC_01049 1.71e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EHFOKGKC_01050 1.43e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EHFOKGKC_01051 3.89e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHFOKGKC_01052 1.68e-275 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EHFOKGKC_01053 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHFOKGKC_01054 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHFOKGKC_01055 4.08e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EHFOKGKC_01056 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EHFOKGKC_01057 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EHFOKGKC_01058 3.85e-125 ywjB - - H - - - RibD C-terminal domain
EHFOKGKC_01059 7.2e-144 yyaS - - S ko:K07149 - ko00000 Membrane
EHFOKGKC_01060 6.12e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHFOKGKC_01061 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EHFOKGKC_01062 6.65e-17 - - - S - - - Protein of unknown function (DUF1433)
EHFOKGKC_01063 3.36e-62 - - - S - - - Protein of unknown function (DUF1433)
EHFOKGKC_01064 1.54e-50 - - - IU - - - Lipase (class 3)
EHFOKGKC_01065 1.43e-33 - - - S - - - Protein of unknown function (DUF1433)
EHFOKGKC_01066 4.02e-31 - - - S - - - Protein of unknown function (DUF1433)
EHFOKGKC_01068 0.0 - - - I - - - Pfam Lipase (class 3)
EHFOKGKC_01069 3.08e-44 - - - - - - - -
EHFOKGKC_01071 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHFOKGKC_01072 2.01e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
EHFOKGKC_01073 1.11e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EHFOKGKC_01074 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EHFOKGKC_01075 1.12e-208 yraN - - K - - - Transcriptional regulator
EHFOKGKC_01076 2.46e-271 yraM - - S - - - PrpF protein
EHFOKGKC_01077 0.0 - - - EGP - - - Sugar (and other) transporter
EHFOKGKC_01079 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EHFOKGKC_01080 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EHFOKGKC_01081 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHFOKGKC_01082 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHFOKGKC_01083 6.9e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHFOKGKC_01084 5.54e-105 - - - M - - - Ribonuclease
EHFOKGKC_01085 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EHFOKGKC_01086 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EHFOKGKC_01087 6.02e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EHFOKGKC_01088 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EHFOKGKC_01089 6e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EHFOKGKC_01090 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHFOKGKC_01091 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EHFOKGKC_01092 1.1e-198 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EHFOKGKC_01093 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EHFOKGKC_01094 1.94e-245 sasA - - T - - - Histidine kinase
EHFOKGKC_01095 6.61e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_01096 1.67e-74 - - - - - - - -
EHFOKGKC_01097 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EHFOKGKC_01098 8.12e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EHFOKGKC_01099 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EHFOKGKC_01100 1.88e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHFOKGKC_01101 4.67e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHFOKGKC_01102 2.75e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EHFOKGKC_01103 2.23e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHFOKGKC_01104 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EHFOKGKC_01105 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EHFOKGKC_01106 1.19e-176 yvpB - - NU - - - protein conserved in bacteria
EHFOKGKC_01107 4.65e-95 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHFOKGKC_01108 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EHFOKGKC_01109 8.74e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHFOKGKC_01110 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHFOKGKC_01111 1.07e-282 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHFOKGKC_01112 9.04e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHFOKGKC_01113 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EHFOKGKC_01114 5.16e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHFOKGKC_01115 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EHFOKGKC_01116 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EHFOKGKC_01117 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EHFOKGKC_01118 3.2e-218 yvlB - - S - - - Putative adhesin
EHFOKGKC_01119 4.87e-66 yvlA - - - - - - -
EHFOKGKC_01120 2.97e-50 yvkN - - - - - - -
EHFOKGKC_01121 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EHFOKGKC_01122 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EHFOKGKC_01123 2.59e-45 csbA - - S - - - protein conserved in bacteria
EHFOKGKC_01124 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EHFOKGKC_01125 6.66e-144 yvkB - - K - - - Transcriptional regulator
EHFOKGKC_01126 5.92e-298 yvkA - - P - - - -transporter
EHFOKGKC_01127 4.5e-233 - - - S - - - Psort location CytoplasmicMembrane, score
EHFOKGKC_01128 8.77e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHFOKGKC_01129 2.47e-73 swrA - - S - - - Swarming motility protein
EHFOKGKC_01130 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHFOKGKC_01131 4.92e-304 ywoF - - P - - - Right handed beta helix region
EHFOKGKC_01132 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EHFOKGKC_01133 5.86e-157 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EHFOKGKC_01134 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHFOKGKC_01135 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_01136 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHFOKGKC_01137 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EHFOKGKC_01138 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHFOKGKC_01139 1.35e-89 - - - - - - - -
EHFOKGKC_01140 5.61e-10 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EHFOKGKC_01141 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EHFOKGKC_01142 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHFOKGKC_01143 1.97e-139 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHFOKGKC_01144 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHFOKGKC_01145 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EHFOKGKC_01146 2.8e-108 yviE - - - - - - -
EHFOKGKC_01147 5.69e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EHFOKGKC_01148 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EHFOKGKC_01149 3.64e-104 yvyG - - NOU - - - FlgN protein
EHFOKGKC_01150 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EHFOKGKC_01151 1.1e-97 yvyF - - S - - - flagellar protein
EHFOKGKC_01152 1.43e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EHFOKGKC_01153 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EHFOKGKC_01154 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EHFOKGKC_01155 8.81e-204 degV - - S - - - protein conserved in bacteria
EHFOKGKC_01156 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_01157 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EHFOKGKC_01158 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EHFOKGKC_01159 1.9e-230 yvhJ - - K - - - Transcriptional regulator
EHFOKGKC_01160 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EHFOKGKC_01161 7.43e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EHFOKGKC_01162 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHFOKGKC_01163 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EHFOKGKC_01164 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EHFOKGKC_01165 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHFOKGKC_01166 5.31e-284 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EHFOKGKC_01167 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_01168 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHFOKGKC_01169 1.99e-264 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHFOKGKC_01170 0.0 lytB - - D - - - Stage II sporulation protein
EHFOKGKC_01171 3.45e-40 - - - - - - - -
EHFOKGKC_01172 2.33e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EHFOKGKC_01173 1.2e-234 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EHFOKGKC_01174 3.04e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHFOKGKC_01175 9.74e-238 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EHFOKGKC_01176 5.47e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EHFOKGKC_01177 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHFOKGKC_01178 7.22e-305 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
EHFOKGKC_01179 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EHFOKGKC_01180 6.38e-184 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EHFOKGKC_01181 2.85e-265 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHFOKGKC_01182 9.86e-169 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHFOKGKC_01183 4.04e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHFOKGKC_01184 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHFOKGKC_01185 4.46e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHFOKGKC_01186 6.05e-272 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EHFOKGKC_01187 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
EHFOKGKC_01188 3.45e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHFOKGKC_01189 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
EHFOKGKC_01190 1.3e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHFOKGKC_01191 4.5e-77 yttA - - S - - - Pfam Transposase IS66
EHFOKGKC_01192 2.73e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHFOKGKC_01193 4.04e-29 ywtC - - - - - - -
EHFOKGKC_01194 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EHFOKGKC_01195 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EHFOKGKC_01196 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EHFOKGKC_01197 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EHFOKGKC_01198 4.4e-247 - - - E - - - Spore germination protein
EHFOKGKC_01199 2.62e-262 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
EHFOKGKC_01200 3.51e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EHFOKGKC_01201 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHFOKGKC_01202 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EHFOKGKC_01203 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EHFOKGKC_01204 4.4e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHFOKGKC_01205 5.69e-207 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EHFOKGKC_01206 3.54e-117 batE - - T - - - Sh3 type 3 domain protein
EHFOKGKC_01207 5.02e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EHFOKGKC_01208 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EHFOKGKC_01209 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EHFOKGKC_01210 8.86e-214 alsR - - K - - - LysR substrate binding domain
EHFOKGKC_01211 1.04e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHFOKGKC_01212 3.43e-163 ywrJ - - - - - - -
EHFOKGKC_01213 1.29e-185 cotB - - - ko:K06325 - ko00000 -
EHFOKGKC_01214 2.76e-271 cotH - - M ko:K06330 - ko00000 Spore Coat
EHFOKGKC_01215 9.51e-25 - - - - - - - -
EHFOKGKC_01216 6.96e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHFOKGKC_01218 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHFOKGKC_01219 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHFOKGKC_01220 5.97e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EHFOKGKC_01221 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EHFOKGKC_01222 4.32e-173 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EHFOKGKC_01223 7.91e-120 - - - - - - - -
EHFOKGKC_01224 6.52e-98 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
EHFOKGKC_01225 8.47e-84 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
EHFOKGKC_01226 3.23e-297 ywqJ - - S - - - Pre-toxin TG
EHFOKGKC_01227 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
EHFOKGKC_01230 9.83e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
EHFOKGKC_01231 5.88e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHFOKGKC_01232 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EHFOKGKC_01233 6.33e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHFOKGKC_01234 1.01e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EHFOKGKC_01235 1.74e-21 - - - - - - - -
EHFOKGKC_01236 0.0 ywqB - - S - - - SWIM zinc finger
EHFOKGKC_01237 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHFOKGKC_01238 7.5e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHFOKGKC_01239 4.82e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
EHFOKGKC_01240 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EHFOKGKC_01241 4.49e-82 ywpG - - - - - - -
EHFOKGKC_01242 9.16e-91 ywpF - - S - - - YwpF-like protein
EHFOKGKC_01243 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EHFOKGKC_01244 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHFOKGKC_01245 1.1e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EHFOKGKC_01246 1.14e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHFOKGKC_01247 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHFOKGKC_01248 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EHFOKGKC_01249 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EHFOKGKC_01250 3.58e-93 ywoH - - K - - - transcriptional
EHFOKGKC_01251 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_01252 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EHFOKGKC_01253 2.69e-310 ywoD - - EGP - - - Major facilitator superfamily
EHFOKGKC_01254 1.37e-133 yjgF - - Q - - - Isochorismatase family
EHFOKGKC_01255 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EHFOKGKC_01256 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EHFOKGKC_01257 2.97e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHFOKGKC_01258 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EHFOKGKC_01259 6.63e-95 ywnJ - - S - - - VanZ like family
EHFOKGKC_01260 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHFOKGKC_01261 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EHFOKGKC_01263 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
EHFOKGKC_01264 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHFOKGKC_01265 8.03e-79 ywnC - - S - - - Family of unknown function (DUF5362)
EHFOKGKC_01266 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EHFOKGKC_01267 3.09e-88 ywnA - - K - - - Transcriptional regulator
EHFOKGKC_01268 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EHFOKGKC_01269 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EHFOKGKC_01270 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EHFOKGKC_01271 7.2e-18 csbD - - K - - - CsbD-like
EHFOKGKC_01272 2.58e-106 ywmF - - S - - - Peptidase M50
EHFOKGKC_01273 3.13e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHFOKGKC_01274 7.6e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHFOKGKC_01275 5.24e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHFOKGKC_01277 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHFOKGKC_01278 1.42e-148 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHFOKGKC_01279 1.16e-241 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EHFOKGKC_01280 2.87e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHFOKGKC_01281 1.62e-172 ywmB - - S - - - TATA-box binding
EHFOKGKC_01282 2.25e-45 ywzB - - S - - - membrane
EHFOKGKC_01283 1.76e-118 ywmA - - - - - - -
EHFOKGKC_01284 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EHFOKGKC_01285 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHFOKGKC_01286 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHFOKGKC_01287 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHFOKGKC_01288 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHFOKGKC_01289 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHFOKGKC_01290 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHFOKGKC_01291 8.61e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EHFOKGKC_01292 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EHFOKGKC_01293 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHFOKGKC_01294 1.7e-300 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHFOKGKC_01295 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
EHFOKGKC_01296 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EHFOKGKC_01297 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHFOKGKC_01298 4.76e-119 mntP - - P - - - Probably functions as a manganese efflux pump
EHFOKGKC_01299 2.64e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EHFOKGKC_01300 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EHFOKGKC_01301 2.68e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EHFOKGKC_01302 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EHFOKGKC_01304 1.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EHFOKGKC_01305 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHFOKGKC_01306 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHFOKGKC_01307 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EHFOKGKC_01308 1.52e-197 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EHFOKGKC_01309 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHFOKGKC_01310 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EHFOKGKC_01311 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EHFOKGKC_01312 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHFOKGKC_01313 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EHFOKGKC_01314 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHFOKGKC_01315 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHFOKGKC_01316 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EHFOKGKC_01317 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EHFOKGKC_01318 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
EHFOKGKC_01319 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EHFOKGKC_01320 3.41e-75 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EHFOKGKC_01321 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EHFOKGKC_01322 6.98e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EHFOKGKC_01323 6.93e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EHFOKGKC_01324 1.13e-58 ywjC - - - - - - -
EHFOKGKC_01325 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHFOKGKC_01326 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHFOKGKC_01327 2.04e-134 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHFOKGKC_01328 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EHFOKGKC_01329 8.93e-124 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EHFOKGKC_01330 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EHFOKGKC_01331 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHFOKGKC_01332 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EHFOKGKC_01333 4.34e-178 ywiC - - S - - - YwiC-like protein
EHFOKGKC_01334 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EHFOKGKC_01335 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHFOKGKC_01336 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EHFOKGKC_01337 1.14e-96 ywiB - - S - - - protein conserved in bacteria
EHFOKGKC_01339 1.79e-65 ywhL - - CO - - - amine dehydrogenase activity
EHFOKGKC_01340 2.06e-187 ywhL - - CO - - - amine dehydrogenase activity
EHFOKGKC_01341 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
EHFOKGKC_01342 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHFOKGKC_01344 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
EHFOKGKC_01345 2.41e-45 - - - - - - - -
EHFOKGKC_01346 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
EHFOKGKC_01348 8.45e-101 - - - CP - - - Membrane
EHFOKGKC_01351 1.22e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHFOKGKC_01352 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EHFOKGKC_01353 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHFOKGKC_01354 3.52e-105 - - - - - - - -
EHFOKGKC_01355 9.52e-124 ywhD - - S - - - YwhD family
EHFOKGKC_01356 2.31e-154 ywhC - - S - - - Peptidase family M50
EHFOKGKC_01357 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EHFOKGKC_01358 1.02e-93 ywhA - - K - - - Transcriptional regulator
EHFOKGKC_01359 5.69e-315 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
EHFOKGKC_01360 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
EHFOKGKC_01361 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EHFOKGKC_01362 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EHFOKGKC_01363 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EHFOKGKC_01364 5.36e-68 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
EHFOKGKC_01365 4.59e-121 - - - S - - - membrane
EHFOKGKC_01366 8.16e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01367 1.03e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
EHFOKGKC_01370 1.92e-237 - - - - - - - -
EHFOKGKC_01372 9.14e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EHFOKGKC_01373 2.63e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_01374 7.2e-215 - - - S - - - Conserved hypothetical protein 698
EHFOKGKC_01375 1.18e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EHFOKGKC_01376 1.98e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EHFOKGKC_01377 4.87e-180 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EHFOKGKC_01378 3.14e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EHFOKGKC_01379 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EHFOKGKC_01380 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EHFOKGKC_01381 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_01382 2.41e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EHFOKGKC_01383 3.85e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EHFOKGKC_01384 2.25e-283 ywfA - - EGP - - - -transporter
EHFOKGKC_01385 2.32e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EHFOKGKC_01386 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHFOKGKC_01387 0.0 rocB - - E - - - arginine degradation protein
EHFOKGKC_01388 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHFOKGKC_01389 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHFOKGKC_01390 3.68e-76 - - - - - - - -
EHFOKGKC_01391 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EHFOKGKC_01392 1.16e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EHFOKGKC_01393 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EHFOKGKC_01394 9.8e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHFOKGKC_01395 9.14e-239 spsG - - M - - - Spore Coat
EHFOKGKC_01396 3.53e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
EHFOKGKC_01397 1.01e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EHFOKGKC_01398 1.92e-205 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EHFOKGKC_01399 2.52e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EHFOKGKC_01400 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EHFOKGKC_01401 9.06e-184 spsA - - M - - - Spore Coat
EHFOKGKC_01402 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EHFOKGKC_01403 1.41e-72 ywdK - - S - - - small membrane protein
EHFOKGKC_01404 3.96e-293 ywdJ - - F - - - Xanthine uracil
EHFOKGKC_01405 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
EHFOKGKC_01406 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHFOKGKC_01407 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
EHFOKGKC_01408 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHFOKGKC_01409 3.52e-26 ywdA - - - - - - -
EHFOKGKC_01410 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHFOKGKC_01411 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_01412 1.57e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHFOKGKC_01414 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHFOKGKC_01415 4.5e-234 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_01416 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EHFOKGKC_01417 3.11e-270 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EHFOKGKC_01418 7.46e-101 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EHFOKGKC_01419 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EHFOKGKC_01420 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHFOKGKC_01421 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHFOKGKC_01422 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHFOKGKC_01423 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EHFOKGKC_01424 5.74e-48 ydaS - - S - - - membrane
EHFOKGKC_01425 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EHFOKGKC_01426 2.85e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHFOKGKC_01427 1.71e-81 gtcA - - S - - - GtrA-like protein
EHFOKGKC_01428 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
EHFOKGKC_01430 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
EHFOKGKC_01431 4.9e-172 - - - S - - - Streptomycin biosynthesis protein StrF
EHFOKGKC_01432 2.54e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHFOKGKC_01433 2.83e-304 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EHFOKGKC_01434 9.61e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EHFOKGKC_01435 6.45e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHFOKGKC_01436 4.83e-202 ywbI - - K - - - Transcriptional regulator
EHFOKGKC_01437 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EHFOKGKC_01438 6.47e-144 ywbG - - M - - - effector of murein hydrolase
EHFOKGKC_01439 2.61e-37 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EHFOKGKC_01440 6.89e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EHFOKGKC_01441 5.57e-216 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EHFOKGKC_01442 3.08e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EHFOKGKC_01443 1.76e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EHFOKGKC_01444 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHFOKGKC_01445 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHFOKGKC_01446 6.3e-209 gspA - - M - - - General stress
EHFOKGKC_01447 4.35e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EHFOKGKC_01448 1.07e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EHFOKGKC_01449 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
EHFOKGKC_01450 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_01451 7.34e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EHFOKGKC_01452 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_01453 3.76e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EHFOKGKC_01454 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHFOKGKC_01455 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHFOKGKC_01456 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_01457 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHFOKGKC_01458 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EHFOKGKC_01459 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EHFOKGKC_01460 5.36e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EHFOKGKC_01461 6.37e-218 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_01462 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_01463 2.64e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EHFOKGKC_01464 1.91e-78 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EHFOKGKC_01465 6.03e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHFOKGKC_01466 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_01467 7.89e-66 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_01468 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHFOKGKC_01469 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHFOKGKC_01470 3.77e-215 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EHFOKGKC_01471 5.91e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHFOKGKC_01472 1.53e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EHFOKGKC_01473 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHFOKGKC_01474 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EHFOKGKC_01475 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EHFOKGKC_01476 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHFOKGKC_01477 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EHFOKGKC_01478 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EHFOKGKC_01479 3.07e-239 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EHFOKGKC_01480 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHFOKGKC_01481 2.25e-287 cimH - - C - - - COG3493 Na citrate symporter
EHFOKGKC_01482 1.57e-196 yxkH - - G - - - Polysaccharide deacetylase
EHFOKGKC_01483 1.76e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_01484 9.16e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EHFOKGKC_01485 6.84e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHFOKGKC_01486 8.94e-119 yxkC - - S - - - Domain of unknown function (DUF4352)
EHFOKGKC_01487 6.54e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHFOKGKC_01488 2.82e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EHFOKGKC_01491 6.11e-111 yxjI - - S - - - LURP-one-related
EHFOKGKC_01492 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EHFOKGKC_01493 1.85e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EHFOKGKC_01494 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHFOKGKC_01495 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
EHFOKGKC_01496 2.38e-65 yxiS - - - - - - -
EHFOKGKC_01498 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHFOKGKC_01499 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHFOKGKC_01500 3.44e-186 bglS - - M - - - licheninase activity
EHFOKGKC_01501 3.41e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHFOKGKC_01502 9e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EHFOKGKC_01503 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EHFOKGKC_01506 9.96e-134 - - - - - - - -
EHFOKGKC_01510 2.09e-91 yxiG - - - - - - -
EHFOKGKC_01511 4.19e-87 yxxG - - - - - - -
EHFOKGKC_01518 5.15e-67 - - - - - - - -
EHFOKGKC_01519 0.0 wapA - - M - - - COG3209 Rhs family protein
EHFOKGKC_01520 4.47e-256 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EHFOKGKC_01521 5.94e-208 yxxF - - EG - - - EamA-like transporter family
EHFOKGKC_01522 1.26e-96 yxiE - - T - - - Belongs to the universal stress protein A family
EHFOKGKC_01523 1.04e-196 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHFOKGKC_01524 0.0 - - - L - - - HKD family nuclease
EHFOKGKC_01525 5.87e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHFOKGKC_01526 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHFOKGKC_01527 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EHFOKGKC_01528 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EHFOKGKC_01529 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHFOKGKC_01530 1.44e-295 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EHFOKGKC_01531 7.97e-224 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EHFOKGKC_01532 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHFOKGKC_01533 3.85e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EHFOKGKC_01534 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHFOKGKC_01535 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHFOKGKC_01536 1.43e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHFOKGKC_01537 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
EHFOKGKC_01540 2.06e-42 yxeE - - - - - - -
EHFOKGKC_01541 5.09e-35 yxeD - - - - - - -
EHFOKGKC_01542 2.8e-46 - - - - - - - -
EHFOKGKC_01543 1.44e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EHFOKGKC_01544 6.96e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
EHFOKGKC_01545 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHFOKGKC_01546 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01547 5e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_01548 1.33e-158 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_01549 4.69e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EHFOKGKC_01550 8.8e-203 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EHFOKGKC_01551 1.53e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EHFOKGKC_01552 5.18e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EHFOKGKC_01553 1.56e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EHFOKGKC_01554 7.67e-222 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EHFOKGKC_01555 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EHFOKGKC_01556 1.33e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EHFOKGKC_01557 2.08e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EHFOKGKC_01558 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHFOKGKC_01559 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHFOKGKC_01560 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EHFOKGKC_01561 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHFOKGKC_01562 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EHFOKGKC_01564 2.51e-194 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHFOKGKC_01565 2.62e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_01566 3.94e-253 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_01567 1.38e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EHFOKGKC_01568 1.22e-271 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EHFOKGKC_01569 9.34e-317 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHFOKGKC_01570 1.5e-190 yxaL - - S - - - PQQ-like domain
EHFOKGKC_01571 8.36e-84 - - - S - - - Family of unknown function (DUF5391)
EHFOKGKC_01572 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHFOKGKC_01573 1.27e-254 - - - EGP - - - Major Facilitator Superfamily
EHFOKGKC_01574 7.8e-97 yxaI - - S - - - membrane protein domain
EHFOKGKC_01575 3.53e-158 - - - E - - - Ring-cleavage extradiol dioxygenase
EHFOKGKC_01576 1.93e-05 htpX3 - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 COG0501 Zn-dependent protease with chaperone function
EHFOKGKC_01577 5.92e-116 mrr2 - - V ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
EHFOKGKC_01578 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EHFOKGKC_01579 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EHFOKGKC_01580 2.79e-282 - - - S - - - Fic/DOC family
EHFOKGKC_01581 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_01582 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EHFOKGKC_01583 3.87e-111 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EHFOKGKC_01584 1.63e-198 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EHFOKGKC_01585 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EHFOKGKC_01586 3.43e-115 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EHFOKGKC_01587 1.4e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EHFOKGKC_01588 5.08e-238 - - - S - - - Fusaric acid resistance protein-like
EHFOKGKC_01589 9.29e-27 - - - - - - - -
EHFOKGKC_01590 1.15e-180 - - - S - - - RES
EHFOKGKC_01591 2.73e-129 - - - - - - - -
EHFOKGKC_01592 1.6e-102 - - - - - - - -
EHFOKGKC_01593 5.09e-147 - - - S - - - ATPase (AAA superfamily
EHFOKGKC_01594 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHFOKGKC_01598 6.89e-279 yycP - - - - - - -
EHFOKGKC_01599 7.96e-170 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EHFOKGKC_01600 2.92e-231 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EHFOKGKC_01601 2.4e-112 yycN - - K - - - Acetyltransferase
EHFOKGKC_01603 1.57e-260 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EHFOKGKC_01604 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHFOKGKC_01605 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHFOKGKC_01606 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EHFOKGKC_01607 6.32e-93 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EHFOKGKC_01608 2.69e-57 sdpR - - K - - - transcriptional
EHFOKGKC_01609 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EHFOKGKC_01610 7.53e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
EHFOKGKC_01611 0.0 - - - S - - - ABC transporter
EHFOKGKC_01612 4.27e-257 - - - S - - - Major Facilitator Superfamily
EHFOKGKC_01613 0.0 - - - - - - - -
EHFOKGKC_01614 9e-241 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
EHFOKGKC_01615 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHFOKGKC_01616 1.17e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
EHFOKGKC_01617 1.94e-24 - - - S - - - Peptidase propeptide and YPEB domain
EHFOKGKC_01619 7.73e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHFOKGKC_01620 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EHFOKGKC_01621 1.98e-194 yycI - - S - - - protein conserved in bacteria
EHFOKGKC_01622 0.0 yycH - - S - - - protein conserved in bacteria
EHFOKGKC_01623 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_01624 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_01629 1.55e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHFOKGKC_01630 2.51e-91 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHFOKGKC_01631 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EHFOKGKC_01632 1.82e-37 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EHFOKGKC_01634 5.12e-25 yycC - - K - - - YycC-like protein
EHFOKGKC_01635 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHFOKGKC_01636 1.04e-304 - - - M - - - Glycosyltransferase Family 4
EHFOKGKC_01637 3.69e-258 - - - S - - - Ecdysteroid kinase
EHFOKGKC_01638 3.12e-295 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
EHFOKGKC_01639 5.47e-298 - - - M - - - Glycosyltransferase Family 4
EHFOKGKC_01640 3.57e-156 - - - S - - - GlcNAc-PI de-N-acetylase
EHFOKGKC_01641 3.53e-116 - - - KLT - - - COG0515 Serine threonine protein kinase
EHFOKGKC_01642 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHFOKGKC_01643 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EHFOKGKC_01644 2.9e-203 yybS - - S - - - membrane
EHFOKGKC_01646 3.8e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
EHFOKGKC_01647 4.56e-87 yybR - - K - - - Transcriptional regulator
EHFOKGKC_01648 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EHFOKGKC_01649 1.68e-196 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHFOKGKC_01650 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EHFOKGKC_01651 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EHFOKGKC_01652 1.33e-149 - - - K - - - FCD domain
EHFOKGKC_01653 7.85e-117 - - - S - - - PFAM DinB family protein
EHFOKGKC_01654 6.69e-204 - - - G - - - Major Facilitator Superfamily
EHFOKGKC_01655 1.59e-103 eamA1 - - EG - - - spore germination
EHFOKGKC_01656 1.94e-74 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
EHFOKGKC_01657 1.7e-148 ydgI - - C - - - nitroreductase
EHFOKGKC_01658 1.37e-89 - - - K - - - Winged helix DNA-binding domain
EHFOKGKC_01659 1.38e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_01660 1.44e-99 yybA - - K - - - transcriptional
EHFOKGKC_01661 3.13e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
EHFOKGKC_01662 2.75e-210 - - - M - - - Domain of Unknown Function (DUF1259)
EHFOKGKC_01663 2.37e-29 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EHFOKGKC_01664 3.16e-61 - - - F - - - Belongs to the Nudix hydrolase family
EHFOKGKC_01665 8.08e-15 - - - S ko:K07137 - ko00000 Pyridine nucleotide-disulphide oxidoreductase
EHFOKGKC_01666 3.4e-126 - - - - - - - -
EHFOKGKC_01667 1.33e-86 - - - S - - - Leucine-rich repeat (LRR) protein
EHFOKGKC_01669 1.01e-82 - - - O - - - Subtilase family
EHFOKGKC_01670 4.3e-312 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHFOKGKC_01671 3.85e-164 - - - EG - - - EamA-like transporter family
EHFOKGKC_01672 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EHFOKGKC_01673 2.43e-209 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHFOKGKC_01674 9.38e-317 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
EHFOKGKC_01675 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHFOKGKC_01676 6.9e-232 ccpB - - K - - - Transcriptional regulator
EHFOKGKC_01677 5.83e-50 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EHFOKGKC_01678 4.11e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHFOKGKC_01679 1.26e-136 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EHFOKGKC_01680 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHFOKGKC_01681 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EHFOKGKC_01682 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EHFOKGKC_01683 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EHFOKGKC_01684 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHFOKGKC_01685 1.82e-45 yyzM - - S - - - protein conserved in bacteria
EHFOKGKC_01686 3.36e-225 yyaD - - S - - - Membrane
EHFOKGKC_01687 2.34e-108 yhhY - - K - - - FR47-like protein
EHFOKGKC_01688 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
EHFOKGKC_01689 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EHFOKGKC_01690 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EHFOKGKC_01691 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EHFOKGKC_01692 7.99e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EHFOKGKC_01693 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EHFOKGKC_01694 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHFOKGKC_01695 6.6e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EHFOKGKC_01696 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHFOKGKC_01697 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EHFOKGKC_01698 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHFOKGKC_01699 3.45e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EHFOKGKC_01700 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EHFOKGKC_01701 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHFOKGKC_01702 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
EHFOKGKC_01703 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHFOKGKC_01704 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHFOKGKC_01705 1.97e-73 - - - Q - - - Thioesterase domain
EHFOKGKC_01706 1.62e-19 - - - - - - - -
EHFOKGKC_01707 1.89e-154 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHFOKGKC_01708 6.11e-184 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHFOKGKC_01709 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01710 1.24e-104 - - - KT - - - helix_turn_helix, Lux Regulon
EHFOKGKC_01711 5e-132 - - - T - - - Histidine kinase
EHFOKGKC_01712 7.81e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHFOKGKC_01713 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_01714 9.32e-92 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_01715 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EHFOKGKC_01716 3.49e-134 yxaC - - M - - - effector of murein hydrolase
EHFOKGKC_01717 2.54e-207 dkgB - - S - - - Aldo/keto reductase family
EHFOKGKC_01718 3.7e-166 ybdO - - S - - - Domain of unknown function (DUF4885)
EHFOKGKC_01719 1.07e-124 ybdN - - - - - - -
EHFOKGKC_01720 2.02e-138 - - - S - - - ABC-2 family transporter protein
EHFOKGKC_01721 1.24e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHFOKGKC_01722 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EHFOKGKC_01723 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHFOKGKC_01724 2.59e-300 ybbR - - S - - - protein conserved in bacteria
EHFOKGKC_01725 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHFOKGKC_01726 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EHFOKGKC_01727 1.87e-126 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_01733 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
EHFOKGKC_01734 1.82e-112 ybbJ - - J - - - acetyltransferase
EHFOKGKC_01735 9.86e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHFOKGKC_01736 3.54e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_01737 9.72e-313 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EHFOKGKC_01738 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EHFOKGKC_01739 3.7e-299 ybbC - - S - - - protein conserved in bacteria
EHFOKGKC_01740 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EHFOKGKC_01741 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EHFOKGKC_01742 3.63e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_01743 5.83e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHFOKGKC_01744 1.26e-148 ybbA - - S ko:K07017 - ko00000 Putative esterase
EHFOKGKC_01745 1.54e-222 ybaS - - S - - - Na -dependent transporter
EHFOKGKC_01746 2.25e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHFOKGKC_01747 9.77e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EHFOKGKC_01748 3.68e-229 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
EHFOKGKC_01749 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHFOKGKC_01750 6.41e-281 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EHFOKGKC_01751 3.33e-204 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHFOKGKC_01752 1.15e-113 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHFOKGKC_01753 3.31e-57 - - - - - - - -
EHFOKGKC_01754 9.42e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_01756 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHFOKGKC_01757 8.91e-248 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHFOKGKC_01758 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EHFOKGKC_01759 7.72e-262 yoaB - - EGP - - - the major facilitator superfamily
EHFOKGKC_01760 9.01e-178 yoxB - - - - - - -
EHFOKGKC_01761 6.9e-56 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHFOKGKC_01762 3.49e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_01763 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EHFOKGKC_01764 7.2e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHFOKGKC_01765 3.29e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHFOKGKC_01766 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_01767 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EHFOKGKC_01768 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EHFOKGKC_01769 3.07e-240 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHFOKGKC_01770 1.29e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_01771 3.67e-18 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHFOKGKC_01772 3.29e-67 - - - K - - - Helix-turn-helix domain
EHFOKGKC_01773 2.18e-252 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
EHFOKGKC_01774 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHFOKGKC_01775 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
EHFOKGKC_01776 3.97e-125 - - - L - - - Integrase
EHFOKGKC_01778 3.68e-125 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EHFOKGKC_01779 2.13e-311 yoeA - - V - - - MATE efflux family protein
EHFOKGKC_01780 1.93e-239 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EHFOKGKC_01781 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHFOKGKC_01782 3.23e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EHFOKGKC_01783 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EHFOKGKC_01784 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EHFOKGKC_01785 5.2e-293 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EHFOKGKC_01786 4.48e-189 yqfA - - S - - - UPF0365 protein
EHFOKGKC_01787 1.79e-85 yqfB - - - - - - -
EHFOKGKC_01788 3.57e-61 yqfC - - S - - - sporulation protein YqfC
EHFOKGKC_01789 1.3e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EHFOKGKC_01790 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EHFOKGKC_01791 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EHFOKGKC_01792 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHFOKGKC_01793 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EHFOKGKC_01794 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EHFOKGKC_01795 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHFOKGKC_01796 6e-24 - - - S - - - YqzL-like protein
EHFOKGKC_01797 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EHFOKGKC_01798 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EHFOKGKC_01799 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EHFOKGKC_01800 5.89e-145 ccpN - - K - - - CBS domain
EHFOKGKC_01801 2.22e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EHFOKGKC_01802 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EHFOKGKC_01803 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EHFOKGKC_01804 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHFOKGKC_01805 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHFOKGKC_01806 1.95e-158 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EHFOKGKC_01807 3.1e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHFOKGKC_01808 1.01e-101 yclD - - - - - - -
EHFOKGKC_01809 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EHFOKGKC_01810 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EHFOKGKC_01811 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EHFOKGKC_01812 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EHFOKGKC_01813 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EHFOKGKC_01814 2.9e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHFOKGKC_01815 2.78e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHFOKGKC_01816 7.33e-143 yczE - - S ko:K07149 - ko00000 membrane
EHFOKGKC_01817 1.11e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EHFOKGKC_01818 2.97e-306 ycxD - - K - - - GntR family transcriptional regulator
EHFOKGKC_01819 4.54e-216 ycxC - - EG - - - EamA-like transporter family
EHFOKGKC_01820 3.86e-84 - - - S - - - YcxB-like protein
EHFOKGKC_01821 0.0 - - - E - - - Aminotransferase class I and II
EHFOKGKC_01822 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EHFOKGKC_01823 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EHFOKGKC_01824 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_01825 2.27e-231 yaaC - - S - - - YaaC-like Protein
EHFOKGKC_01826 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EHFOKGKC_01827 9.38e-317 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHFOKGKC_01828 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHFOKGKC_01829 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHFOKGKC_01830 6.46e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHFOKGKC_01831 2.94e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EHFOKGKC_01833 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EHFOKGKC_01834 4.71e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EHFOKGKC_01835 1.23e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EHFOKGKC_01836 5.85e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EHFOKGKC_01837 2.89e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EHFOKGKC_01838 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHFOKGKC_01839 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHFOKGKC_01840 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHFOKGKC_01841 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
EHFOKGKC_01842 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EHFOKGKC_01843 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_01844 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_01846 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHFOKGKC_01847 4.16e-89 yqfQ - - S - - - YqfQ-like protein
EHFOKGKC_01848 3.5e-307 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EHFOKGKC_01849 1.72e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHFOKGKC_01850 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EHFOKGKC_01851 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_01852 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EHFOKGKC_01853 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EHFOKGKC_01854 6.74e-80 yqfX - - S - - - membrane
EHFOKGKC_01855 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHFOKGKC_01856 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
EHFOKGKC_01857 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
EHFOKGKC_01858 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EHFOKGKC_01859 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EHFOKGKC_01860 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EHFOKGKC_01861 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EHFOKGKC_01865 6.45e-70 yjcN - - - - - - -
EHFOKGKC_01866 5.51e-159 - - - G - - - Cupin
EHFOKGKC_01867 5.93e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHFOKGKC_01868 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHFOKGKC_01869 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHFOKGKC_01870 2.03e-122 yuaB - - - - - - -
EHFOKGKC_01871 2.89e-124 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EHFOKGKC_01872 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHFOKGKC_01873 1.43e-289 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EHFOKGKC_01874 6.79e-141 - - - S - - - MOSC domain
EHFOKGKC_01875 8.91e-106 yuaE - - S - - - DinB superfamily
EHFOKGKC_01876 1.96e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EHFOKGKC_01877 1.45e-275 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EHFOKGKC_01878 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EHFOKGKC_01880 6.7e-148 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHFOKGKC_01881 5e-116 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHFOKGKC_01882 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHFOKGKC_01883 6.48e-148 ypjP - - S - - - YpjP-like protein
EHFOKGKC_01884 3.49e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EHFOKGKC_01885 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
EHFOKGKC_01886 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EHFOKGKC_01887 1.15e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EHFOKGKC_01888 1.33e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EHFOKGKC_01889 1.13e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EHFOKGKC_01890 1.89e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHFOKGKC_01891 5.21e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EHFOKGKC_01892 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EHFOKGKC_01893 1.27e-17 degR - - - - - - -
EHFOKGKC_01894 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EHFOKGKC_01895 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EHFOKGKC_01896 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHFOKGKC_01897 7.22e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EHFOKGKC_01898 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHFOKGKC_01899 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHFOKGKC_01900 6.11e-169 yteA - - T - - - COG1734 DnaK suppressor protein
EHFOKGKC_01901 9.03e-103 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EHFOKGKC_01923 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHFOKGKC_01924 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHFOKGKC_01925 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHFOKGKC_01926 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_01927 8.19e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHFOKGKC_01928 1.99e-193 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EHFOKGKC_01929 2.35e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EHFOKGKC_01930 6.33e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
EHFOKGKC_01932 3.1e-137 ytqB - - J - - - Putative rRNA methylase
EHFOKGKC_01933 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EHFOKGKC_01934 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_01935 1.13e-249 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHFOKGKC_01936 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
EHFOKGKC_01938 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EHFOKGKC_01939 8.47e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01940 7.55e-219 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_01941 3.13e-227 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_01942 9.55e-203 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EHFOKGKC_01943 1.22e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01944 1.36e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EHFOKGKC_01945 5.25e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_01946 3.11e-215 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EHFOKGKC_01947 2.68e-173 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_01948 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EHFOKGKC_01949 7.28e-158 ywaF - - S - - - Integral membrane protein
EHFOKGKC_01950 2.87e-270 yttB - - EGP - - - Major facilitator superfamily
EHFOKGKC_01951 6.17e-177 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EHFOKGKC_01952 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
EHFOKGKC_01953 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EHFOKGKC_01954 6.05e-69 ytwF - - P - - - Sulfurtransferase
EHFOKGKC_01955 8.07e-110 - - - M - - - Acetyltransferase (GNAT) domain
EHFOKGKC_01956 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EHFOKGKC_01957 2.88e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHFOKGKC_01958 2.54e-214 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHFOKGKC_01959 6.55e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHFOKGKC_01960 3.87e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_01961 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EHFOKGKC_01962 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EHFOKGKC_01963 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EHFOKGKC_01964 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_01965 1.01e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHFOKGKC_01966 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EHFOKGKC_01967 2.58e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHFOKGKC_01968 1.5e-277 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EHFOKGKC_01969 2.99e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EHFOKGKC_01970 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EHFOKGKC_01971 4.79e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHFOKGKC_01972 1.1e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EHFOKGKC_01973 2.85e-214 ytlQ - - - - - - -
EHFOKGKC_01974 1.96e-225 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EHFOKGKC_01975 2.93e-199 ytmP - - M - - - Phosphotransferase
EHFOKGKC_01976 3.88e-60 ytzH - - S - - - YtzH-like protein
EHFOKGKC_01977 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EHFOKGKC_01978 4.57e-210 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHFOKGKC_01979 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHFOKGKC_01980 9.96e-69 ytzB - - S - - - small secreted protein
EHFOKGKC_01981 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EHFOKGKC_01982 1.42e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EHFOKGKC_01983 1.57e-75 ytpP - - CO - - - Thioredoxin
EHFOKGKC_01984 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
EHFOKGKC_01985 2.43e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHFOKGKC_01986 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHFOKGKC_01987 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EHFOKGKC_01988 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHFOKGKC_01989 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EHFOKGKC_01990 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
EHFOKGKC_01991 6.28e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EHFOKGKC_01992 2.06e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EHFOKGKC_01993 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHFOKGKC_01994 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHFOKGKC_01995 1.17e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EHFOKGKC_01996 7.2e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EHFOKGKC_01997 1.71e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EHFOKGKC_01998 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHFOKGKC_01999 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHFOKGKC_02000 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
EHFOKGKC_02001 5.77e-160 ygaZ - - E - - - AzlC protein
EHFOKGKC_02002 7.76e-191 - - - K - - - Transcriptional regulator
EHFOKGKC_02003 1.74e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHFOKGKC_02004 1.14e-174 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EHFOKGKC_02006 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHFOKGKC_02008 2.41e-279 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHFOKGKC_02009 1.74e-130 yokH - - G - - - SMI1 / KNR4 family
EHFOKGKC_02010 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHFOKGKC_02011 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHFOKGKC_02012 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EHFOKGKC_02013 2.48e-111 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EHFOKGKC_02014 5.69e-140 yttP - - K - - - Transcriptional regulator
EHFOKGKC_02015 2.42e-195 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EHFOKGKC_02016 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EHFOKGKC_02017 1.32e-306 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHFOKGKC_02018 2.25e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHFOKGKC_02019 2.44e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHFOKGKC_02020 1.34e-40 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EHFOKGKC_02021 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHFOKGKC_02022 0.0 ytcJ - - S - - - amidohydrolase
EHFOKGKC_02023 3.16e-194 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHFOKGKC_02024 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EHFOKGKC_02025 7.94e-114 yteJ - - S - - - RDD family
EHFOKGKC_02026 1.26e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
EHFOKGKC_02027 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
EHFOKGKC_02028 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EHFOKGKC_02029 1.06e-234 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EHFOKGKC_02030 1.06e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHFOKGKC_02031 2.24e-112 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EHFOKGKC_02032 1.23e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EHFOKGKC_02033 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EHFOKGKC_02035 3.41e-183 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_02036 8.4e-166 ytkL - - S - - - Belongs to the UPF0173 family
EHFOKGKC_02037 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
EHFOKGKC_02038 3.05e-63 ytpI - - S - - - YtpI-like protein
EHFOKGKC_02039 3.04e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EHFOKGKC_02040 1e-31 - - - - - - - -
EHFOKGKC_02041 3.08e-113 ytrI - - - - - - -
EHFOKGKC_02042 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
EHFOKGKC_02043 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EHFOKGKC_02044 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHFOKGKC_02045 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHFOKGKC_02046 1.34e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EHFOKGKC_02047 1.14e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHFOKGKC_02048 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EHFOKGKC_02049 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EHFOKGKC_02050 4.52e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
EHFOKGKC_02051 1.92e-96 ytwI - - S - - - membrane
EHFOKGKC_02052 3.87e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EHFOKGKC_02053 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHFOKGKC_02054 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EHFOKGKC_02055 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EHFOKGKC_02056 1.38e-165 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHFOKGKC_02057 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EHFOKGKC_02058 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHFOKGKC_02059 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EHFOKGKC_02060 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EHFOKGKC_02061 3.43e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHFOKGKC_02062 5.53e-206 ytbE - - S - - - reductase
EHFOKGKC_02063 1.97e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EHFOKGKC_02064 1.69e-89 ytcD - - K - - - Transcriptional regulator
EHFOKGKC_02065 2.19e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHFOKGKC_02066 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EHFOKGKC_02067 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHFOKGKC_02068 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EHFOKGKC_02069 1.66e-218 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EHFOKGKC_02070 8.99e-140 ytxB - - S - - - SNARE associated Golgi protein
EHFOKGKC_02071 7.21e-196 ytxC - - S - - - YtxC-like family
EHFOKGKC_02072 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHFOKGKC_02073 7.21e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EHFOKGKC_02074 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_02075 3e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EHFOKGKC_02076 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
EHFOKGKC_02077 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EHFOKGKC_02078 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHFOKGKC_02079 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EHFOKGKC_02080 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHFOKGKC_02081 3.16e-55 ysdA - - S - - - Membrane
EHFOKGKC_02082 5.63e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
EHFOKGKC_02083 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
EHFOKGKC_02084 5.73e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHFOKGKC_02085 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EHFOKGKC_02086 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EHFOKGKC_02087 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EHFOKGKC_02088 3.06e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EHFOKGKC_02089 1.65e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EHFOKGKC_02090 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EHFOKGKC_02091 6.22e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
EHFOKGKC_02092 6.84e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EHFOKGKC_02093 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EHFOKGKC_02094 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EHFOKGKC_02095 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EHFOKGKC_02096 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
EHFOKGKC_02097 2.93e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EHFOKGKC_02098 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EHFOKGKC_02099 3.65e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHFOKGKC_02100 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHFOKGKC_02101 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHFOKGKC_02102 8.83e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHFOKGKC_02103 3.48e-53 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHFOKGKC_02104 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
EHFOKGKC_02105 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EHFOKGKC_02106 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHFOKGKC_02107 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
EHFOKGKC_02108 9.2e-32 ywbB - - S - - - Protein of unknown function (DUF2711)
EHFOKGKC_02109 2.31e-107 ywbB - - S - - - Protein of unknown function (DUF2711)
EHFOKGKC_02110 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHFOKGKC_02111 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02112 1.23e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EHFOKGKC_02113 1.43e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EHFOKGKC_02114 1.01e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EHFOKGKC_02115 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EHFOKGKC_02116 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EHFOKGKC_02117 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EHFOKGKC_02118 8.64e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHFOKGKC_02119 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
EHFOKGKC_02120 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EHFOKGKC_02121 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHFOKGKC_02122 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHFOKGKC_02123 2.19e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EHFOKGKC_02124 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02125 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_02126 4.68e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EHFOKGKC_02127 4.47e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EHFOKGKC_02128 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHFOKGKC_02129 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHFOKGKC_02130 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EHFOKGKC_02134 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
EHFOKGKC_02135 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
EHFOKGKC_02136 2.34e-142 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
EHFOKGKC_02137 2.15e-116 res - - L - - - Resolvase, N terminal domain
EHFOKGKC_02140 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHFOKGKC_02141 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHFOKGKC_02142 2.26e-243 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHFOKGKC_02143 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHFOKGKC_02144 1.68e-252 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EHFOKGKC_02145 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHFOKGKC_02146 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHFOKGKC_02147 9.14e-239 ysoA - - H - - - Tetratricopeptide repeat
EHFOKGKC_02148 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EHFOKGKC_02149 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHFOKGKC_02150 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EHFOKGKC_02151 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHFOKGKC_02152 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EHFOKGKC_02153 3.93e-114 ysxD - - - - - - -
EHFOKGKC_02154 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHFOKGKC_02155 1.88e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
EHFOKGKC_02156 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EHFOKGKC_02157 1.62e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHFOKGKC_02158 1.4e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EHFOKGKC_02159 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHFOKGKC_02160 4.38e-302 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EHFOKGKC_02161 3.66e-249 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHFOKGKC_02162 1.53e-35 - - - - - - - -
EHFOKGKC_02163 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EHFOKGKC_02164 2.18e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EHFOKGKC_02165 1.81e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EHFOKGKC_02166 1.27e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EHFOKGKC_02167 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EHFOKGKC_02168 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EHFOKGKC_02169 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EHFOKGKC_02170 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EHFOKGKC_02171 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EHFOKGKC_02172 3.96e-154 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EHFOKGKC_02173 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EHFOKGKC_02174 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHFOKGKC_02175 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EHFOKGKC_02176 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EHFOKGKC_02177 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EHFOKGKC_02178 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EHFOKGKC_02179 1.48e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EHFOKGKC_02180 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHFOKGKC_02181 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EHFOKGKC_02182 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EHFOKGKC_02183 3.02e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EHFOKGKC_02184 2.72e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHFOKGKC_02185 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EHFOKGKC_02186 3.16e-197 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EHFOKGKC_02187 1.73e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHFOKGKC_02188 2.96e-257 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EHFOKGKC_02189 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHFOKGKC_02191 4.21e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EHFOKGKC_02192 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EHFOKGKC_02193 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EHFOKGKC_02194 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
EHFOKGKC_02195 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHFOKGKC_02196 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EHFOKGKC_02197 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EHFOKGKC_02198 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
EHFOKGKC_02199 2.03e-143 yrbG - - S - - - membrane
EHFOKGKC_02200 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_02201 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
EHFOKGKC_02202 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHFOKGKC_02203 2.18e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHFOKGKC_02204 2.14e-60 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EHFOKGKC_02205 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EHFOKGKC_02206 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHFOKGKC_02207 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHFOKGKC_02208 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EHFOKGKC_02209 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EHFOKGKC_02212 6.05e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EHFOKGKC_02213 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHFOKGKC_02214 2.39e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EHFOKGKC_02215 9.19e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EHFOKGKC_02216 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02217 2.1e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHFOKGKC_02218 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EHFOKGKC_02219 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
EHFOKGKC_02220 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EHFOKGKC_02221 1.76e-107 yrrD - - S - - - protein conserved in bacteria
EHFOKGKC_02222 8.4e-42 yrzR - - - - - - -
EHFOKGKC_02223 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
EHFOKGKC_02224 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHFOKGKC_02225 3.94e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHFOKGKC_02226 4.27e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHFOKGKC_02227 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHFOKGKC_02228 2.7e-236 yrrI - - S - - - AI-2E family transporter
EHFOKGKC_02229 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHFOKGKC_02230 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
EHFOKGKC_02231 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHFOKGKC_02232 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
EHFOKGKC_02233 1.15e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHFOKGKC_02234 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EHFOKGKC_02235 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EHFOKGKC_02236 5.4e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EHFOKGKC_02237 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EHFOKGKC_02238 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHFOKGKC_02239 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EHFOKGKC_02240 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
EHFOKGKC_02241 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
EHFOKGKC_02242 2.94e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EHFOKGKC_02243 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHFOKGKC_02244 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EHFOKGKC_02245 4.58e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHFOKGKC_02246 9.51e-47 yrhC - - S - - - YrhC-like protein
EHFOKGKC_02247 3.91e-105 yrhD - - S - - - Protein of unknown function (DUF1641)
EHFOKGKC_02248 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EHFOKGKC_02249 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EHFOKGKC_02250 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EHFOKGKC_02251 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EHFOKGKC_02252 9.01e-121 yrhH - - Q - - - methyltransferase
EHFOKGKC_02253 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EHFOKGKC_02254 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHFOKGKC_02255 3.77e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_02256 7.57e-211 yybE - - K - - - Transcriptional regulator
EHFOKGKC_02257 5.61e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHFOKGKC_02258 1.98e-232 romA - - S - - - Beta-lactamase superfamily domain
EHFOKGKC_02259 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EHFOKGKC_02260 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_02261 2.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHFOKGKC_02262 4.12e-168 - - - K - - - Helix-turn-helix domain, rpiR family
EHFOKGKC_02263 1.23e-173 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHFOKGKC_02264 3.98e-188 supH - - S - - - hydrolase
EHFOKGKC_02265 6.77e-121 - - - S - - - DinB family
EHFOKGKC_02266 2.89e-103 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EHFOKGKC_02267 7.59e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_02268 5.25e-41 - - - K - - - acetyltransferase
EHFOKGKC_02269 1.83e-128 yqaC - - F - - - adenylate kinase activity
EHFOKGKC_02270 1.76e-130 yrkN - - K - - - Acetyltransferase (GNAT) family
EHFOKGKC_02272 3.14e-275 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EHFOKGKC_02273 1.33e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EHFOKGKC_02274 1.58e-300 yrkQ - - T - - - Histidine kinase
EHFOKGKC_02275 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
EHFOKGKC_02276 1.63e-121 - - - K - - - Transcriptional regulator PadR-like family
EHFOKGKC_02277 6.2e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
EHFOKGKC_02278 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_02279 1.82e-276 - - - EGP - - - Transmembrane secretion effector
EHFOKGKC_02280 4.51e-47 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHFOKGKC_02281 4.84e-137 yqeD - - S - - - SNARE associated Golgi protein
EHFOKGKC_02282 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHFOKGKC_02283 3.07e-179 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EHFOKGKC_02285 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EHFOKGKC_02286 1.13e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EHFOKGKC_02287 2.32e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHFOKGKC_02288 6.3e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EHFOKGKC_02289 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHFOKGKC_02290 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EHFOKGKC_02291 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EHFOKGKC_02292 8.39e-179 yqeM - - Q - - - Methyltransferase
EHFOKGKC_02293 2.3e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHFOKGKC_02294 3.42e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EHFOKGKC_02295 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EHFOKGKC_02296 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EHFOKGKC_02297 3.68e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EHFOKGKC_02298 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EHFOKGKC_02299 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EHFOKGKC_02300 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EHFOKGKC_02301 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
EHFOKGKC_02302 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EHFOKGKC_02303 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EHFOKGKC_02304 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EHFOKGKC_02305 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHFOKGKC_02306 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EHFOKGKC_02307 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EHFOKGKC_02308 6.58e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EHFOKGKC_02309 2.91e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EHFOKGKC_02310 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EHFOKGKC_02311 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
EHFOKGKC_02312 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EHFOKGKC_02313 1.75e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EHFOKGKC_02314 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHFOKGKC_02315 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EHFOKGKC_02316 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHFOKGKC_02317 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
EHFOKGKC_02318 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EHFOKGKC_02319 5.15e-100 ytkA - - S - - - YtkA-like
EHFOKGKC_02321 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EHFOKGKC_02322 3.51e-79 ytkC - - S - - - Bacteriophage holin family
EHFOKGKC_02323 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHFOKGKC_02324 7.52e-174 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EHFOKGKC_02325 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHFOKGKC_02326 2.15e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EHFOKGKC_02327 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EHFOKGKC_02328 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
EHFOKGKC_02329 7.44e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EHFOKGKC_02330 6.32e-228 yplP - - K - - - Transcriptional regulator
EHFOKGKC_02331 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EHFOKGKC_02332 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
EHFOKGKC_02333 5.51e-147 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EHFOKGKC_02334 1.61e-172 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EHFOKGKC_02335 1.6e-125 ypmS - - S - - - protein conserved in bacteria
EHFOKGKC_02336 8.22e-90 ypoP - - K - - - transcriptional
EHFOKGKC_02337 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHFOKGKC_02338 4.44e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EHFOKGKC_02339 2.93e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHFOKGKC_02340 0.0 yokA - - L - - - Recombinase
EHFOKGKC_02341 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_02342 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EHFOKGKC_02343 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EHFOKGKC_02344 6.14e-80 - - - S - - - phosphoglycolate phosphatase activity
EHFOKGKC_02345 8.57e-216 yunF - - S - - - Protein of unknown function DUF72
EHFOKGKC_02346 1.23e-185 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EHFOKGKC_02347 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHFOKGKC_02349 1.52e-74 yokK - - S - - - SMI1 / KNR4 family
EHFOKGKC_02350 3.75e-80 - - - S - - - Protein of unknown function, DUF600
EHFOKGKC_02351 1.25e-108 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
EHFOKGKC_02352 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
EHFOKGKC_02353 2.43e-240 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EHFOKGKC_02355 5.18e-30 - - - - - - - -
EHFOKGKC_02356 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHFOKGKC_02357 3.6e-122 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EHFOKGKC_02358 1.07e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHFOKGKC_02359 2.72e-142 ymaB - - S - - - MutT family
EHFOKGKC_02360 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHFOKGKC_02361 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHFOKGKC_02362 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EHFOKGKC_02363 9.42e-29 ymzA - - - - - - -
EHFOKGKC_02364 6e-59 - - - - - - - -
EHFOKGKC_02365 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EHFOKGKC_02366 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHFOKGKC_02367 5.96e-77 ymaF - - S - - - YmaF family
EHFOKGKC_02369 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHFOKGKC_02370 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHFOKGKC_02371 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EHFOKGKC_02372 6.85e-164 ymaC - - S - - - Replication protein
EHFOKGKC_02373 3.03e-06 - - - - - - - -
EHFOKGKC_02374 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EHFOKGKC_02375 1.61e-81 ymzB - - - - - - -
EHFOKGKC_02376 1.28e-152 yoaK - - S - - - Membrane
EHFOKGKC_02377 6.07e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
EHFOKGKC_02378 3.95e-293 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHFOKGKC_02379 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EHFOKGKC_02380 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHFOKGKC_02381 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_02382 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_02383 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHFOKGKC_02384 1.62e-178 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EHFOKGKC_02385 6.15e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EHFOKGKC_02386 1.04e-308 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EHFOKGKC_02387 2.51e-47 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EHFOKGKC_02388 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_02389 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EHFOKGKC_02390 4.05e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_02391 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EHFOKGKC_02394 3.97e-49 - - - - - - - -
EHFOKGKC_02395 2.34e-88 - - - L - - - Belongs to the 'phage' integrase family
EHFOKGKC_02396 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHFOKGKC_02397 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHFOKGKC_02398 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EHFOKGKC_02399 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EHFOKGKC_02400 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHFOKGKC_02401 1.01e-273 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHFOKGKC_02402 6.82e-250 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EHFOKGKC_02403 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EHFOKGKC_02404 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EHFOKGKC_02405 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EHFOKGKC_02406 5.46e-279 pbpX - - V - - - Beta-lactamase
EHFOKGKC_02407 2.51e-238 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHFOKGKC_02408 9.36e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EHFOKGKC_02409 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHFOKGKC_02410 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EHFOKGKC_02411 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
EHFOKGKC_02412 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
EHFOKGKC_02413 7.08e-165 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EHFOKGKC_02414 4.79e-309 ymfH - - S - - - zinc protease
EHFOKGKC_02415 1.31e-305 albE - - S - - - Peptidase M16
EHFOKGKC_02416 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EHFOKGKC_02417 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_02418 9.04e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_02419 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02420 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHFOKGKC_02421 3.66e-41 - - - S - - - YlzJ-like protein
EHFOKGKC_02422 1.31e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EHFOKGKC_02423 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHFOKGKC_02424 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHFOKGKC_02425 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHFOKGKC_02426 4.97e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHFOKGKC_02427 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EHFOKGKC_02428 1.91e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EHFOKGKC_02429 2.17e-56 ymxH - - S - - - YlmC YmxH family
EHFOKGKC_02430 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
EHFOKGKC_02431 1.02e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EHFOKGKC_02432 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EHFOKGKC_02433 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHFOKGKC_02434 7.46e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EHFOKGKC_02435 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHFOKGKC_02436 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHFOKGKC_02437 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EHFOKGKC_02438 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHFOKGKC_02439 6.16e-63 ylxQ - - J - - - ribosomal protein
EHFOKGKC_02440 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EHFOKGKC_02441 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EHFOKGKC_02442 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EHFOKGKC_02443 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHFOKGKC_02444 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EHFOKGKC_02445 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EHFOKGKC_02446 7.68e-274 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EHFOKGKC_02447 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EHFOKGKC_02448 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHFOKGKC_02449 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EHFOKGKC_02450 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EHFOKGKC_02451 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHFOKGKC_02452 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EHFOKGKC_02453 7.11e-95 ylxL - - - - - - -
EHFOKGKC_02454 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_02455 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EHFOKGKC_02456 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EHFOKGKC_02457 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EHFOKGKC_02458 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EHFOKGKC_02459 2.02e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EHFOKGKC_02460 6.35e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EHFOKGKC_02461 6.52e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EHFOKGKC_02462 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHFOKGKC_02463 1.46e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHFOKGKC_02464 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EHFOKGKC_02465 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EHFOKGKC_02466 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EHFOKGKC_02467 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EHFOKGKC_02468 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EHFOKGKC_02469 1.21e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHFOKGKC_02470 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHFOKGKC_02471 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EHFOKGKC_02472 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EHFOKGKC_02473 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EHFOKGKC_02474 7.04e-259 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EHFOKGKC_02475 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
EHFOKGKC_02476 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EHFOKGKC_02477 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EHFOKGKC_02478 9.29e-121 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EHFOKGKC_02479 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHFOKGKC_02480 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EHFOKGKC_02481 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EHFOKGKC_02482 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EHFOKGKC_02483 8.02e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EHFOKGKC_02484 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EHFOKGKC_02485 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHFOKGKC_02486 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHFOKGKC_02487 3.64e-219 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EHFOKGKC_02488 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHFOKGKC_02489 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHFOKGKC_02490 1.27e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EHFOKGKC_02491 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EHFOKGKC_02492 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EHFOKGKC_02493 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EHFOKGKC_02494 0.0 ylqG - - - - - - -
EHFOKGKC_02495 4.59e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHFOKGKC_02496 7.24e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHFOKGKC_02497 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EHFOKGKC_02498 3.42e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EHFOKGKC_02499 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHFOKGKC_02500 3.41e-80 ylqD - - S - - - YlqD protein
EHFOKGKC_02501 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EHFOKGKC_02502 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EHFOKGKC_02503 1.16e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHFOKGKC_02504 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHFOKGKC_02505 1.44e-180 - - - S - - - Phosphotransferase enzyme family
EHFOKGKC_02506 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EHFOKGKC_02507 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EHFOKGKC_02508 6.09e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EHFOKGKC_02509 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHFOKGKC_02510 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHFOKGKC_02511 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_02512 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EHFOKGKC_02513 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EHFOKGKC_02514 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHFOKGKC_02515 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHFOKGKC_02516 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHFOKGKC_02517 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EHFOKGKC_02518 3.65e-78 yloU - - S - - - protein conserved in bacteria
EHFOKGKC_02519 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EHFOKGKC_02520 1.3e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EHFOKGKC_02521 2.31e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EHFOKGKC_02522 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EHFOKGKC_02523 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHFOKGKC_02524 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EHFOKGKC_02525 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EHFOKGKC_02526 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHFOKGKC_02527 7.57e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHFOKGKC_02528 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHFOKGKC_02529 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHFOKGKC_02530 2.18e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHFOKGKC_02531 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EHFOKGKC_02532 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EHFOKGKC_02533 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EHFOKGKC_02534 3.04e-198 yloC - - S - - - stress-induced protein
EHFOKGKC_02535 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EHFOKGKC_02536 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EHFOKGKC_02537 6.27e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EHFOKGKC_02538 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EHFOKGKC_02539 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHFOKGKC_02540 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EHFOKGKC_02541 3.72e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EHFOKGKC_02542 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EHFOKGKC_02543 4.03e-180 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EHFOKGKC_02545 7.37e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHFOKGKC_02546 1.05e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EHFOKGKC_02547 3e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHFOKGKC_02548 1.01e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EHFOKGKC_02549 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EHFOKGKC_02550 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHFOKGKC_02551 1.28e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EHFOKGKC_02552 3.61e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EHFOKGKC_02553 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EHFOKGKC_02554 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHFOKGKC_02555 3.09e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EHFOKGKC_02556 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHFOKGKC_02557 1.79e-84 ylyA - - T - - - COG1734 DnaK suppressor protein
EHFOKGKC_02558 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHFOKGKC_02559 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EHFOKGKC_02560 3.54e-181 ylmH - - S - - - conserved protein, contains S4-like domain
EHFOKGKC_02561 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EHFOKGKC_02562 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EHFOKGKC_02563 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHFOKGKC_02564 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EHFOKGKC_02565 7.13e-52 ylmC - - S - - - sporulation protein
EHFOKGKC_02566 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EHFOKGKC_02567 1.33e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EHFOKGKC_02568 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_02569 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_02570 9.6e-217 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EHFOKGKC_02571 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EHFOKGKC_02572 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHFOKGKC_02573 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EHFOKGKC_02574 3.8e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EHFOKGKC_02575 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EHFOKGKC_02576 4.67e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHFOKGKC_02577 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHFOKGKC_02578 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHFOKGKC_02579 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHFOKGKC_02580 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHFOKGKC_02581 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EHFOKGKC_02582 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHFOKGKC_02583 2.4e-68 ftsL - - D - - - Essential cell division protein
EHFOKGKC_02584 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EHFOKGKC_02585 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EHFOKGKC_02586 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EHFOKGKC_02587 1.68e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHFOKGKC_02588 1.14e-116 ylbP - - K - - - n-acetyltransferase
EHFOKGKC_02589 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EHFOKGKC_02590 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EHFOKGKC_02591 4.88e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EHFOKGKC_02592 2.13e-294 ylbM - - S - - - Belongs to the UPF0348 family
EHFOKGKC_02593 3.07e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EHFOKGKC_02594 3.52e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHFOKGKC_02595 2.91e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EHFOKGKC_02596 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHFOKGKC_02597 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EHFOKGKC_02598 2.78e-57 ylbG - - S - - - UPF0298 protein
EHFOKGKC_02599 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
EHFOKGKC_02600 1.73e-48 ylbE - - S - - - YlbE-like protein
EHFOKGKC_02601 8.47e-87 ylbD - - S - - - Putative coat protein
EHFOKGKC_02602 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
EHFOKGKC_02603 1.36e-95 ylbB - - T - - - COG0517 FOG CBS domain
EHFOKGKC_02604 1.68e-78 ylbA - - S - - - YugN-like family
EHFOKGKC_02605 7.27e-252 - - - L - - - COG3666 Transposase and inactivated derivatives
EHFOKGKC_02620 1.73e-108 - - - G - - - SMI1-KNR4 cell-wall
EHFOKGKC_02621 3.05e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
EHFOKGKC_02622 6.35e-27 - - - - - - - -
EHFOKGKC_02624 3.29e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHFOKGKC_02625 6.25e-268 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHFOKGKC_02626 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EHFOKGKC_02627 2e-120 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EHFOKGKC_02628 1.05e-97 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHFOKGKC_02630 1.76e-47 - - - K - - - SpoVT / AbrB like domain
EHFOKGKC_02631 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EHFOKGKC_02632 1.53e-158 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHFOKGKC_02633 2.99e-162 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EHFOKGKC_02634 1.23e-48 - - - - - - - -
EHFOKGKC_02635 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHFOKGKC_02636 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
EHFOKGKC_02637 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHFOKGKC_02640 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
EHFOKGKC_02641 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EHFOKGKC_02642 8.38e-36 cotW - - - ko:K06341 - ko00000 -
EHFOKGKC_02643 4.33e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EHFOKGKC_02644 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EHFOKGKC_02645 1.12e-103 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EHFOKGKC_02646 3.38e-125 yjbX - - S - - - Spore coat protein
EHFOKGKC_02647 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EHFOKGKC_02648 3.03e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHFOKGKC_02649 1.65e-242 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHFOKGKC_02650 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EHFOKGKC_02651 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
EHFOKGKC_02652 5.56e-269 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EHFOKGKC_02653 1.63e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EHFOKGKC_02654 4.88e-178 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHFOKGKC_02655 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EHFOKGKC_02656 1.84e-184 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EHFOKGKC_02657 2.86e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHFOKGKC_02658 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHFOKGKC_02659 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EHFOKGKC_02660 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
EHFOKGKC_02661 3.48e-128 yjbK - - S - - - protein conserved in bacteria
EHFOKGKC_02662 3.28e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHFOKGKC_02663 7.06e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EHFOKGKC_02664 2.46e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHFOKGKC_02665 3.14e-27 - - - - - - - -
EHFOKGKC_02666 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EHFOKGKC_02667 4.68e-281 coiA - - S ko:K06198 - ko00000 Competence protein
EHFOKGKC_02668 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHFOKGKC_02669 2.77e-141 yjbE - - P - - - Integral membrane protein TerC family
EHFOKGKC_02670 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EHFOKGKC_02671 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHFOKGKC_02672 1.49e-296 - - - S - - - Putative glycosyl hydrolase domain
EHFOKGKC_02673 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02674 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02675 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_02676 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_02677 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHFOKGKC_02678 2.51e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EHFOKGKC_02679 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
EHFOKGKC_02680 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_02681 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_02682 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EHFOKGKC_02683 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02684 1.45e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02685 1.84e-190 yjaZ - - O - - - Zn-dependent protease
EHFOKGKC_02686 5.48e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHFOKGKC_02687 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHFOKGKC_02688 2.82e-44 yjzB - - - - - - -
EHFOKGKC_02689 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EHFOKGKC_02690 1.9e-212 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EHFOKGKC_02691 9.68e-134 yjaV - - - - - - -
EHFOKGKC_02692 1.83e-177 yjaU - - I - - - carboxylic ester hydrolase activity
EHFOKGKC_02693 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
EHFOKGKC_02694 7.21e-39 yjzC - - S - - - YjzC-like protein
EHFOKGKC_02695 2.48e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHFOKGKC_02696 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EHFOKGKC_02697 2.41e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHFOKGKC_02698 6.88e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EHFOKGKC_02699 6.04e-174 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EHFOKGKC_02700 6.29e-291 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHFOKGKC_02701 3.02e-254 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHFOKGKC_02702 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
EHFOKGKC_02703 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EHFOKGKC_02704 3.22e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EHFOKGKC_02705 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EHFOKGKC_02706 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHFOKGKC_02707 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHFOKGKC_02708 1.49e-11 - - - - - - - -
EHFOKGKC_02709 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
EHFOKGKC_02710 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
EHFOKGKC_02711 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHFOKGKC_02712 9.13e-202 yitS - - S - - - protein conserved in bacteria
EHFOKGKC_02714 8.51e-306 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EHFOKGKC_02715 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EHFOKGKC_02716 1.54e-221 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
EHFOKGKC_02717 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EHFOKGKC_02718 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EHFOKGKC_02719 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EHFOKGKC_02720 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
EHFOKGKC_02721 6.14e-108 yisX - - S - - - Pentapeptide repeats (9 copies)
EHFOKGKC_02722 1.68e-239 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHFOKGKC_02723 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EHFOKGKC_02724 3.11e-116 yisT - - S - - - DinB family
EHFOKGKC_02725 1.35e-205 yisR - - K - - - Transcriptional regulator
EHFOKGKC_02726 9.14e-312 yisQ - - V - - - Mate efflux family protein
EHFOKGKC_02727 2.3e-172 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EHFOKGKC_02728 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHFOKGKC_02729 1.59e-125 yisN - - S - - - Protein of unknown function (DUF2777)
EHFOKGKC_02730 6.36e-78 yisL - - S - - - UPF0344 protein
EHFOKGKC_02731 8.91e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EHFOKGKC_02732 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
EHFOKGKC_02733 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EHFOKGKC_02734 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
EHFOKGKC_02735 3.46e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EHFOKGKC_02736 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EHFOKGKC_02737 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EHFOKGKC_02738 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EHFOKGKC_02739 1.53e-66 yisB - - V - - - COG1403 Restriction endonuclease
EHFOKGKC_02740 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EHFOKGKC_02741 3.31e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EHFOKGKC_02742 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EHFOKGKC_02743 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EHFOKGKC_02744 2.46e-160 ydfS - - S - - - Protein of unknown function (DUF421)
EHFOKGKC_02745 1.79e-122 yhjR - - S - - - Rubrerythrin
EHFOKGKC_02746 3.05e-139 - - - K - - - QacR-like protein, C-terminal region
EHFOKGKC_02747 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_02748 4.88e-262 yhjN - - S ko:K07120 - ko00000 membrane
EHFOKGKC_02749 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_02750 0.0 yhjG - - CH - - - FAD binding domain
EHFOKGKC_02751 9.51e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHFOKGKC_02752 1.64e-144 yhjE - - S - - - SNARE associated Golgi protein
EHFOKGKC_02753 5.86e-79 yhjD - - - - - - -
EHFOKGKC_02754 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
EHFOKGKC_02755 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHFOKGKC_02756 2.64e-63 - - - S - - - Belongs to the UPF0145 family
EHFOKGKC_02757 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
EHFOKGKC_02758 3.65e-162 yrpD - - S - - - Domain of unknown function, YrpD
EHFOKGKC_02759 1.41e-119 - - - S - - - MepB protein
EHFOKGKC_02760 1.36e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EHFOKGKC_02761 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EHFOKGKC_02762 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EHFOKGKC_02763 9.48e-43 yhzC - - S - - - IDEAL
EHFOKGKC_02764 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_02765 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EHFOKGKC_02766 9.28e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EHFOKGKC_02767 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EHFOKGKC_02768 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHFOKGKC_02769 7.74e-257 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHFOKGKC_02770 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EHFOKGKC_02771 2.6e-201 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EHFOKGKC_02772 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHFOKGKC_02773 1.11e-301 yhfN - - O - - - Peptidase M48
EHFOKGKC_02774 2.38e-86 yhfM - - - - - - -
EHFOKGKC_02775 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHFOKGKC_02776 2.58e-142 yhfK - - GM - - - NmrA-like family
EHFOKGKC_02777 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EHFOKGKC_02778 6.93e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EHFOKGKC_02780 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHFOKGKC_02781 2.46e-249 yhfE - - G - - - peptidase M42
EHFOKGKC_02783 8.41e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHFOKGKC_02784 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EHFOKGKC_02785 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02786 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EHFOKGKC_02787 5.24e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EHFOKGKC_02788 1.04e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHFOKGKC_02789 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHFOKGKC_02790 2.55e-116 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EHFOKGKC_02791 1.62e-310 yhfA - - C - - - membrane
EHFOKGKC_02792 2.53e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EHFOKGKC_02793 1.43e-160 ecsC - - S - - - EcsC protein family
EHFOKGKC_02794 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EHFOKGKC_02795 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EHFOKGKC_02796 1.67e-104 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EHFOKGKC_02797 2.31e-256 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHFOKGKC_02798 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
EHFOKGKC_02799 2.55e-24 - - - - - - - -
EHFOKGKC_02800 2.74e-54 yhaH - - S - - - YtxH-like protein
EHFOKGKC_02801 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EHFOKGKC_02802 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
EHFOKGKC_02803 1.29e-123 yhaK - - S - - - Putative zincin peptidase
EHFOKGKC_02804 7.58e-185 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EHFOKGKC_02805 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
EHFOKGKC_02806 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EHFOKGKC_02807 0.0 yhaN - - L - - - AAA domain
EHFOKGKC_02808 3.55e-298 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EHFOKGKC_02809 1.13e-275 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EHFOKGKC_02810 1.12e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_02811 9.58e-18 - - - S - - - YhzD-like protein
EHFOKGKC_02812 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
EHFOKGKC_02814 1.87e-113 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHFOKGKC_02815 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EHFOKGKC_02816 5.77e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
EHFOKGKC_02817 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EHFOKGKC_02818 8.46e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EHFOKGKC_02819 4.79e-256 yhaZ - - L - - - DNA alkylation repair enzyme
EHFOKGKC_02820 9.47e-70 yheA - - S - - - Belongs to the UPF0342 family
EHFOKGKC_02821 1.36e-264 yheB - - S - - - Belongs to the UPF0754 family
EHFOKGKC_02822 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
EHFOKGKC_02823 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EHFOKGKC_02824 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
EHFOKGKC_02825 7.8e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EHFOKGKC_02827 1.35e-142 yheG - - GM - - - NAD(P)H-binding
EHFOKGKC_02828 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHFOKGKC_02829 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHFOKGKC_02831 1.18e-108 - - - T - - - universal stress protein
EHFOKGKC_02832 2.29e-125 ymcC - - S - - - Membrane
EHFOKGKC_02833 1.22e-114 pksA - - K - - - Transcriptional regulator
EHFOKGKC_02834 1.19e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EHFOKGKC_02835 1.7e-201 nodB1 - - G - - - deacetylase
EHFOKGKC_02836 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EHFOKGKC_02837 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EHFOKGKC_02838 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
EHFOKGKC_02839 5.21e-165 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHFOKGKC_02840 4.77e-77 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHFOKGKC_02841 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHFOKGKC_02842 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EHFOKGKC_02843 1.35e-301 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHFOKGKC_02844 3.33e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHFOKGKC_02845 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EHFOKGKC_02846 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHFOKGKC_02847 3.75e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHFOKGKC_02848 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_02849 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
EHFOKGKC_02850 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
EHFOKGKC_02851 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHFOKGKC_02852 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
EHFOKGKC_02853 9.14e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_02854 5.72e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHFOKGKC_02855 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02856 2.62e-176 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHFOKGKC_02857 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EHFOKGKC_02858 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EHFOKGKC_02859 0.0 ygxB - - M - - - Conserved TM helix
EHFOKGKC_02860 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EHFOKGKC_02861 1.48e-297 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHFOKGKC_02862 4.18e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
EHFOKGKC_02863 5.75e-52 yhdB - - S - - - YhdB-like protein
EHFOKGKC_02864 2.92e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EHFOKGKC_02865 1.05e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHFOKGKC_02866 1.02e-260 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_02867 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EHFOKGKC_02868 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHFOKGKC_02869 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHFOKGKC_02870 3.85e-197 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHFOKGKC_02871 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EHFOKGKC_02872 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHFOKGKC_02873 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHFOKGKC_02874 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
EHFOKGKC_02875 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
EHFOKGKC_02876 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
EHFOKGKC_02877 3.92e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHFOKGKC_02878 4.55e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EHFOKGKC_02879 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHFOKGKC_02880 1.81e-150 yhcQ - - M - - - Spore coat protein
EHFOKGKC_02881 1.12e-205 yhcP - - - - - - -
EHFOKGKC_02882 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHFOKGKC_02883 5.51e-80 yhcM - - - - - - -
EHFOKGKC_02884 1.29e-293 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHFOKGKC_02885 3.92e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EHFOKGKC_02886 5.86e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EHFOKGKC_02887 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
EHFOKGKC_02888 6.38e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHFOKGKC_02889 1.93e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_02890 1.03e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_02891 4.35e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_02892 1.33e-65 - - - - - - - -
EHFOKGKC_02893 1.41e-72 yhcC - - - - - - -
EHFOKGKC_02894 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHFOKGKC_02895 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHFOKGKC_02896 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EHFOKGKC_02897 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EHFOKGKC_02898 1.77e-280 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EHFOKGKC_02899 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EHFOKGKC_02900 1.23e-07 - - - - - - - -
EHFOKGKC_02901 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHFOKGKC_02902 1.14e-84 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHFOKGKC_02903 1.39e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
EHFOKGKC_02904 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EHFOKGKC_02905 2.13e-226 yhbB - - S - - - Putative amidase domain
EHFOKGKC_02906 2.42e-286 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHFOKGKC_02907 1.58e-146 yhzB - - S - - - B3/4 domain
EHFOKGKC_02909 5.25e-106 ygaO - - - - - - -
EHFOKGKC_02910 1.14e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHFOKGKC_02911 3.51e-272 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EHFOKGKC_02912 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHFOKGKC_02913 2.13e-230 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EHFOKGKC_02914 4.5e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EHFOKGKC_02915 5.69e-235 - - - S ko:K07045 - ko00000 Amidohydrolase
EHFOKGKC_02916 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHFOKGKC_02917 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02918 7.73e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_02919 4.37e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_02920 2.02e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHFOKGKC_02921 4.47e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
EHFOKGKC_02923 0.0 ygaK - - C - - - Berberine and berberine like
EHFOKGKC_02924 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHFOKGKC_02925 4.02e-171 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EHFOKGKC_02926 0.0 - - - C - - - Na+/H+ antiporter family
EHFOKGKC_02943 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_02944 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
EHFOKGKC_02945 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
EHFOKGKC_02946 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EHFOKGKC_02947 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHFOKGKC_02948 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHFOKGKC_02949 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EHFOKGKC_02950 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EHFOKGKC_02951 1.48e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EHFOKGKC_02952 8.28e-177 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EHFOKGKC_02953 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHFOKGKC_02954 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
EHFOKGKC_02955 8.78e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHFOKGKC_02956 2.26e-95 yngA - - S - - - membrane
EHFOKGKC_02957 2.32e-186 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EHFOKGKC_02958 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EHFOKGKC_02959 4.12e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHFOKGKC_02960 7.76e-169 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHFOKGKC_02961 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHFOKGKC_02962 4.36e-283 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHFOKGKC_02963 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EHFOKGKC_02964 1.48e-160 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHFOKGKC_02965 5.26e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHFOKGKC_02966 6.8e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHFOKGKC_02967 3.21e-286 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_02968 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_02969 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_02970 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_02971 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHFOKGKC_02972 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
EHFOKGKC_02973 1.32e-164 - - - T - - - Transcriptional regulatory protein, C terminal
EHFOKGKC_02974 5.77e-37 - - - T - - - Histidine kinase
EHFOKGKC_02975 2.42e-203 - - - T - - - Histidine kinase
EHFOKGKC_02976 3.64e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
EHFOKGKC_02977 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EHFOKGKC_02978 9.75e-218 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
EHFOKGKC_02981 4.96e-83 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHFOKGKC_02982 4.17e-89 - - - S ko:K02004 - ko00000,ko00002,ko02000 Protein of unknown function (DUF1430)
EHFOKGKC_02987 1.3e-173 - - - S - - - COG0457 FOG TPR repeat
EHFOKGKC_02989 2.99e-34 - - - - - - - -
EHFOKGKC_02991 0.0 yndJ - - S - - - YndJ-like protein
EHFOKGKC_02992 1.11e-99 - - - S - - - Domain of unknown function (DUF4166)
EHFOKGKC_02993 6.47e-205 yndG - - S - - - DoxX-like family
EHFOKGKC_02994 3.21e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
EHFOKGKC_02995 1.5e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
EHFOKGKC_02996 1.06e-193 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHFOKGKC_02997 2.67e-269 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EHFOKGKC_02998 7.48e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EHFOKGKC_02999 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EHFOKGKC_03000 3.68e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EHFOKGKC_03001 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHFOKGKC_03002 1.82e-63 ynfC - - - - - - -
EHFOKGKC_03003 2.21e-19 - - - - - - - -
EHFOKGKC_03004 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHFOKGKC_03005 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHFOKGKC_03006 5.75e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EHFOKGKC_03007 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHFOKGKC_03008 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
EHFOKGKC_03009 7.79e-70 yneQ - - - - - - -
EHFOKGKC_03010 1.7e-96 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EHFOKGKC_03011 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EHFOKGKC_03013 9.94e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHFOKGKC_03014 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EHFOKGKC_03015 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EHFOKGKC_03016 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EHFOKGKC_03017 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
EHFOKGKC_03018 4.83e-98 yneK - - S - - - Protein of unknown function (DUF2621)
EHFOKGKC_03019 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EHFOKGKC_03020 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EHFOKGKC_03021 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EHFOKGKC_03022 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
EHFOKGKC_03023 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EHFOKGKC_03024 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EHFOKGKC_03025 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHFOKGKC_03026 2.33e-43 ynzC - - S - - - UPF0291 protein
EHFOKGKC_03027 4.29e-144 yneB - - L - - - resolvase
EHFOKGKC_03028 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EHFOKGKC_03029 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHFOKGKC_03031 2.25e-95 yndM - - S - - - Protein of unknown function (DUF2512)
EHFOKGKC_03032 6.29e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
EHFOKGKC_03033 1.74e-11 - - - - - - - -
EHFOKGKC_03034 2.03e-184 yndL - - S - - - Replication protein
EHFOKGKC_03035 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EHFOKGKC_03036 0.0 yobO - - M - - - Pectate lyase superfamily protein
EHFOKGKC_03038 2.14e-123 yvgO - - - - - - -
EHFOKGKC_03039 1.5e-82 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHFOKGKC_03040 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHFOKGKC_03041 1.12e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
EHFOKGKC_03042 4.15e-258 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_03043 3.47e-154 - - - S - - - Domain of unknown function (DUF3885)
EHFOKGKC_03045 4.66e-128 - - - J - - - Acetyltransferase (GNAT) domain
EHFOKGKC_03046 4.81e-183 yoaP - - K - - - YoaP-like
EHFOKGKC_03047 5.72e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EHFOKGKC_03048 5.74e-26 yoaW - - - - - - -
EHFOKGKC_03049 6.73e-23 - - - - - - - -
EHFOKGKC_03050 1.2e-236 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EHFOKGKC_03051 1.7e-72 dinB - - S - - - DinB family
EHFOKGKC_03052 2.21e-27 - - - - - - - -
EHFOKGKC_03055 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EHFOKGKC_03056 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EHFOKGKC_03057 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EHFOKGKC_03058 7.75e-279 xylR - - GK - - - ROK family
EHFOKGKC_03059 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHFOKGKC_03060 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EHFOKGKC_03061 5.57e-271 mrjp - - G - - - Major royal jelly protein
EHFOKGKC_03062 4.4e-83 yokK - - S - - - SMI1 / KNR4 family
EHFOKGKC_03063 2.13e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHFOKGKC_03064 2.57e-288 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHFOKGKC_03065 5.15e-117 yokH - - G - - - SMI1 / KNR4 family
EHFOKGKC_03066 8.75e-42 - - - - - - - -
EHFOKGKC_03068 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EHFOKGKC_03069 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EHFOKGKC_03070 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EHFOKGKC_03071 5.44e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHFOKGKC_03072 1.3e-89 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EHFOKGKC_03073 1.66e-309 - - - L ko:K06400 - ko00000 Recombinase
EHFOKGKC_03075 1.22e-119 recU - - L ko:K03700 - ko00000,ko03400 DNA recombination
EHFOKGKC_03090 1.1e-189 - - - S - - - Calcineurin-like phosphoesterase
EHFOKGKC_03095 6.98e-69 - - - - - - - -
EHFOKGKC_03099 4.19e-35 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHFOKGKC_03100 3.82e-192 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHFOKGKC_03101 4.26e-59 - - - S - - - Protein of unknown function (DUF1643)
EHFOKGKC_03106 1.8e-72 ymaB - - S - - - MutT family
EHFOKGKC_03109 3.95e-37 - - - O - - - Glutaredoxin
EHFOKGKC_03110 2.71e-228 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHFOKGKC_03111 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHFOKGKC_03112 1.53e-73 - - - S - - - NrdI Flavodoxin like
EHFOKGKC_03117 1.61e-08 - - - S - - - YopX protein
EHFOKGKC_03128 5.26e-112 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EHFOKGKC_03129 4.33e-92 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
EHFOKGKC_03132 1.48e-30 - - - S - - - protein conserved in bacteria
EHFOKGKC_03133 0.0 - - - L - - - DNA polymerase elongation subunit (Family B)
EHFOKGKC_03134 4.26e-218 - - - S - - - PD-(D/E)XK nuclease superfamily
EHFOKGKC_03135 2.07e-187 - - - L - - - DNA primase activity
EHFOKGKC_03136 7.55e-306 - - - L - - - DnaB-like helicase C terminal domain
EHFOKGKC_03138 1.45e-208 - - - S - - - AAA domain
EHFOKGKC_03139 8.33e-224 - - - - - - - -
EHFOKGKC_03140 1.54e-87 - - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
EHFOKGKC_03146 9.29e-274 - - - M - - - Parallel beta-helix repeats
EHFOKGKC_03147 5.2e-111 - - - S - - - Pfam:DUF867
EHFOKGKC_03149 1.06e-29 - - - S - - - YopX protein
EHFOKGKC_03152 3.84e-160 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EHFOKGKC_03153 2.74e-176 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
EHFOKGKC_03156 1.21e-65 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
EHFOKGKC_03163 5.26e-97 - - - N - - - bacterial-type flagellum assembly
EHFOKGKC_03170 0.000188 - - - S - - - YopX protein
EHFOKGKC_03171 4.53e-55 - - - - - - - -
EHFOKGKC_03175 9.24e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_03177 6.3e-237 - - - - - - - -
EHFOKGKC_03183 2.4e-81 - - - - - - - -
EHFOKGKC_03195 6.23e-13 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EHFOKGKC_03196 5.36e-92 yoaW - - - - - - -
EHFOKGKC_03198 0.000613 - - - I - - - Acyltransferase family
EHFOKGKC_03206 2.64e-248 - - - L - - - Domain of unknown function (DUF4942)
EHFOKGKC_03207 4.19e-05 - - - L - - - SNF2 family N-terminal domain
EHFOKGKC_03208 5.89e-204 - - - - - - - -
EHFOKGKC_03211 6.07e-39 - - - D - - - nuclear chromosome segregation
EHFOKGKC_03212 1.94e-73 - - - D - - - Tubulin/FtsZ family, GTPase domain
EHFOKGKC_03216 0.0 - - - - - - - -
EHFOKGKC_03217 6.78e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHFOKGKC_03221 6.29e-291 - - - S - - - hydrolase activity
EHFOKGKC_03226 3.95e-107 - - - - - - - -
EHFOKGKC_03230 8.56e-85 - - - - - - - -
EHFOKGKC_03233 2.55e-71 - - - - - - - -
EHFOKGKC_03234 1.04e-111 - - - - - - - -
EHFOKGKC_03235 9.4e-149 - - - - - - - -
EHFOKGKC_03236 1.42e-73 - - - - - - - -
EHFOKGKC_03238 3.02e-65 - - - - - - - -
EHFOKGKC_03239 1.22e-40 - - - - - - - -
EHFOKGKC_03241 1.56e-104 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
EHFOKGKC_03242 3.11e-70 - - - - - - - -
EHFOKGKC_03243 2.71e-66 - - - - - - - -
EHFOKGKC_03244 1.92e-140 xerH - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
EHFOKGKC_03245 1.83e-26 - - - - - - - -
EHFOKGKC_03248 2.86e-69 - - - - - - - -
EHFOKGKC_03249 0.0 - - - S - - - peptidoglycan catabolic process
EHFOKGKC_03250 6.18e-109 - - - S - - - Phage tail protein
EHFOKGKC_03251 5.75e-242 - - - S - - - Pfam Transposase IS66
EHFOKGKC_03252 1.17e-156 - - - - - - - -
EHFOKGKC_03253 0.0 - - - M - - - Pectate lyase superfamily protein
EHFOKGKC_03254 1.13e-99 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHFOKGKC_03256 7.46e-45 - - - S - - - Bacteriophage holin
EHFOKGKC_03258 2.4e-08 - - - - - - - -
EHFOKGKC_03259 1.18e-118 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHFOKGKC_03261 1.25e-282 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHFOKGKC_03262 3.11e-54 - - - S - - - YolD-like protein
EHFOKGKC_03265 4.87e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHFOKGKC_03266 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EHFOKGKC_03267 8.36e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EHFOKGKC_03268 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EHFOKGKC_03269 9.22e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHFOKGKC_03270 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EHFOKGKC_03271 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EHFOKGKC_03272 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHFOKGKC_03273 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHFOKGKC_03274 1.65e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHFOKGKC_03275 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EHFOKGKC_03276 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHFOKGKC_03277 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHFOKGKC_03278 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EHFOKGKC_03279 5.94e-119 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EHFOKGKC_03281 2.28e-72 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 accessory gene regulator B
EHFOKGKC_03282 1.27e-71 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
EHFOKGKC_03284 2.8e-240 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
EHFOKGKC_03287 3.93e-164 - - - V - - - PFAM Lanthionine synthetase
EHFOKGKC_03288 6.02e-266 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
EHFOKGKC_03289 4.13e-43 - - - - - - - -
EHFOKGKC_03290 1.23e-174 bcrA1 - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_03291 5.74e-124 bcrB1 - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_03292 9.86e-142 mrsE1 - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_03293 7.82e-35 lanR - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
EHFOKGKC_03294 2.62e-144 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_03295 4.62e-85 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_03296 2.68e-117 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHFOKGKC_03297 4.21e-220 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 COG1404 Subtilisin-like serine proteases
EHFOKGKC_03298 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EHFOKGKC_03299 1.14e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EHFOKGKC_03300 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EHFOKGKC_03301 4.24e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EHFOKGKC_03302 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
EHFOKGKC_03303 1.36e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EHFOKGKC_03304 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHFOKGKC_03305 3.88e-163 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EHFOKGKC_03306 8.25e-210 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EHFOKGKC_03307 0.0 oatA - - I - - - Acyltransferase family
EHFOKGKC_03308 7.99e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
EHFOKGKC_03309 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_03310 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EHFOKGKC_03311 7.91e-83 ydjM - - M - - - Lytic transglycolase
EHFOKGKC_03312 2.47e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EHFOKGKC_03314 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
EHFOKGKC_03315 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EHFOKGKC_03316 1.77e-314 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_03317 2.91e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHFOKGKC_03318 6.84e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EHFOKGKC_03319 2.69e-275 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EHFOKGKC_03320 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EHFOKGKC_03321 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EHFOKGKC_03322 4.68e-72 - - - S - - - Pentapeptide repeat protein
EHFOKGKC_03323 2.97e-156 - - - K - - - Acetyltransferase (GNAT) domain
EHFOKGKC_03324 2.31e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_03325 0.0 - - - S - - - Domain of unknown function (DUF4179)
EHFOKGKC_03326 2.04e-268 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EHFOKGKC_03327 1.36e-171 yebC - - M - - - Membrane
EHFOKGKC_03329 4.41e-119 yebE - - S - - - UPF0316 protein
EHFOKGKC_03330 6.56e-40 yebG - - S - - - NETI protein
EHFOKGKC_03331 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHFOKGKC_03332 9.19e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHFOKGKC_03333 8.99e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHFOKGKC_03334 7.13e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EHFOKGKC_03335 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHFOKGKC_03336 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHFOKGKC_03337 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHFOKGKC_03338 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHFOKGKC_03339 2.53e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EHFOKGKC_03340 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHFOKGKC_03341 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EHFOKGKC_03342 8.08e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EHFOKGKC_03343 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
EHFOKGKC_03344 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EHFOKGKC_03345 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EHFOKGKC_03346 2.03e-67 yerC - - S - - - protein conserved in bacteria
EHFOKGKC_03347 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EHFOKGKC_03348 1.76e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EHFOKGKC_03349 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EHFOKGKC_03350 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHFOKGKC_03351 3.2e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EHFOKGKC_03352 1.48e-247 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EHFOKGKC_03353 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EHFOKGKC_03354 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHFOKGKC_03355 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHFOKGKC_03356 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EHFOKGKC_03357 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHFOKGKC_03358 9.07e-197 yerO - - K - - - Transcriptional regulator
EHFOKGKC_03359 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHFOKGKC_03360 4.95e-216 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHFOKGKC_03361 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHFOKGKC_03362 1.83e-231 - - - L - - - AAA ATPase domain
EHFOKGKC_03363 3.64e-05 - - - L ko:K07459 - ko00000 AAA domain
EHFOKGKC_03364 5.09e-142 - - - L - - - AAA domain
EHFOKGKC_03365 1.38e-74 - - - - - - - -
EHFOKGKC_03366 2.96e-55 - - - S - - - Immunity protein 22
EHFOKGKC_03368 2e-97 - - - S - - - Protein of unknown function, DUF600
EHFOKGKC_03369 1.31e-73 - - - S - - - Protein of unknown function, DUF600
EHFOKGKC_03370 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
EHFOKGKC_03371 1.05e-24 - - - - - - - -
EHFOKGKC_03372 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
EHFOKGKC_03374 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EHFOKGKC_03375 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EHFOKGKC_03376 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EHFOKGKC_03377 4.33e-127 yesJ - - K - - - Acetyltransferase (GNAT) family
EHFOKGKC_03378 4.2e-05 - - - - - - - -
EHFOKGKC_03379 3.01e-155 yetF - - S - - - membrane
EHFOKGKC_03380 6.42e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EHFOKGKC_03381 7.63e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHFOKGKC_03382 1.27e-196 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHFOKGKC_03383 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
EHFOKGKC_03384 1.06e-72 - - - H - - - riboflavin kinase activity
EHFOKGKC_03385 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EHFOKGKC_03386 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_03387 6.72e-262 yetM - - CH - - - FAD binding domain
EHFOKGKC_03388 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
EHFOKGKC_03389 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHFOKGKC_03391 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHFOKGKC_03392 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EHFOKGKC_03393 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EHFOKGKC_03394 2.31e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EHFOKGKC_03395 1.46e-284 yfnE - - S - - - Glycosyltransferase like family 2
EHFOKGKC_03396 3.45e-239 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EHFOKGKC_03397 9.02e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03398 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
EHFOKGKC_03399 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHFOKGKC_03400 4.11e-162 yfmS - - NT - - - chemotaxis protein
EHFOKGKC_03401 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHFOKGKC_03402 5.72e-264 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EHFOKGKC_03403 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHFOKGKC_03404 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EHFOKGKC_03405 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EHFOKGKC_03406 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHFOKGKC_03407 1.53e-265 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EHFOKGKC_03408 4.87e-85 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EHFOKGKC_03409 4.91e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EHFOKGKC_03410 1.1e-30 - - - S - - - Protein of unknown function (DUF3212)
EHFOKGKC_03411 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
EHFOKGKC_03412 4.21e-304 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EHFOKGKC_03413 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EHFOKGKC_03416 4.96e-113 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
EHFOKGKC_03417 0.0 ywpD - - T - - - Histidine kinase
EHFOKGKC_03418 3.54e-193 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
EHFOKGKC_03419 0.0 - - - M - - - cell wall anchor domain
EHFOKGKC_03420 9.62e-105 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EHFOKGKC_03421 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHFOKGKC_03422 2.39e-155 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EHFOKGKC_03423 5.62e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EHFOKGKC_03424 3.33e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHFOKGKC_03425 6.64e-190 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHFOKGKC_03426 1.01e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EHFOKGKC_03427 9.63e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EHFOKGKC_03428 8.55e-131 yflK - - S - - - protein conserved in bacteria
EHFOKGKC_03429 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
EHFOKGKC_03430 1.98e-26 yflI - - - - - - -
EHFOKGKC_03431 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
EHFOKGKC_03432 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHFOKGKC_03433 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EHFOKGKC_03434 1.87e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EHFOKGKC_03435 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHFOKGKC_03436 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EHFOKGKC_03437 1.43e-104 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHFOKGKC_03438 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
EHFOKGKC_03439 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
EHFOKGKC_03440 1.83e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_03441 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHFOKGKC_03442 4.8e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EHFOKGKC_03443 8.4e-158 frp - - C - - - nitroreductase
EHFOKGKC_03444 4.93e-166 yibF - - S - - - YibE/F-like protein
EHFOKGKC_03445 6.6e-257 yibE - - S - - - YibE/F-like protein
EHFOKGKC_03446 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EHFOKGKC_03447 1.58e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHFOKGKC_03448 6.16e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EHFOKGKC_03449 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHFOKGKC_03450 2.38e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EHFOKGKC_03451 3.31e-250 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03452 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
EHFOKGKC_03453 6.88e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHFOKGKC_03454 6.15e-69 yfkI - - S - - - gas vesicle protein
EHFOKGKC_03455 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EHFOKGKC_03456 1.37e-12 - - - - - - - -
EHFOKGKC_03457 8.37e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03458 1.2e-238 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EHFOKGKC_03459 9.38e-185 yfkD - - S - - - YfkD-like protein
EHFOKGKC_03460 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
EHFOKGKC_03461 8.03e-280 yfkA - - S - - - YfkB-like domain
EHFOKGKC_03462 7.99e-37 yfjT - - - - - - -
EHFOKGKC_03463 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EHFOKGKC_03464 2.39e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EHFOKGKC_03466 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EHFOKGKC_03467 1.72e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHFOKGKC_03468 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHFOKGKC_03471 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHFOKGKC_03472 2.71e-116 yfjM - - S - - - Psort location Cytoplasmic, score
EHFOKGKC_03473 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHFOKGKC_03474 7.55e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHFOKGKC_03475 7.99e-274 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHFOKGKC_03476 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHFOKGKC_03477 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EHFOKGKC_03478 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EHFOKGKC_03479 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHFOKGKC_03480 1.28e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EHFOKGKC_03481 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_03482 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
EHFOKGKC_03483 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHFOKGKC_03484 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHFOKGKC_03485 1.36e-82 yfiD3 - - S - - - DoxX
EHFOKGKC_03486 5.51e-204 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EHFOKGKC_03487 2.08e-214 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHFOKGKC_03488 5.62e-126 padR - - K - - - transcriptional
EHFOKGKC_03489 3.61e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHFOKGKC_03490 8.04e-238 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EHFOKGKC_03492 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EHFOKGKC_03493 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EHFOKGKC_03494 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EHFOKGKC_03495 0.0 yfiU - - EGP - - - the major facilitator superfamily
EHFOKGKC_03496 1.38e-108 yfiV - - K - - - transcriptional
EHFOKGKC_03497 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHFOKGKC_03498 2.26e-212 yfhB - - S - - - PhzF family
EHFOKGKC_03499 1.17e-137 yfhC - - C - - - nitroreductase
EHFOKGKC_03500 3.61e-34 yfhD - - S - - - YfhD-like protein
EHFOKGKC_03502 4.94e-214 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EHFOKGKC_03503 3.14e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EHFOKGKC_03504 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
EHFOKGKC_03505 4.06e-268 yfhI - - EGP - - - -transporter
EHFOKGKC_03507 2.45e-216 mpr - - M - - - Belongs to the peptidase S1B family
EHFOKGKC_03508 2.57e-59 yfhJ - - S - - - WVELL protein
EHFOKGKC_03509 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
EHFOKGKC_03510 1.48e-57 yfhL - - S - - - SdpI/YhfL protein family
EHFOKGKC_03511 2.37e-219 - - - S - - - Alpha/beta hydrolase family
EHFOKGKC_03512 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHFOKGKC_03513 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EHFOKGKC_03514 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EHFOKGKC_03515 4.18e-262 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EHFOKGKC_03516 1.47e-49 yfhS - - - - - - -
EHFOKGKC_03517 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_03518 4.52e-08 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EHFOKGKC_03519 1.4e-49 ygaB - - S - - - YgaB-like protein
EHFOKGKC_03520 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EHFOKGKC_03521 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EHFOKGKC_03522 5.48e-239 ygaE - - S - - - Membrane
EHFOKGKC_03523 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHFOKGKC_03524 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EHFOKGKC_03525 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EHFOKGKC_03526 4.67e-75 ygzB - - S - - - UPF0295 protein
EHFOKGKC_03527 4.57e-212 ygxA - - S - - - Nucleotidyltransferase-like
EHFOKGKC_03528 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EHFOKGKC_03529 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHFOKGKC_03530 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EHFOKGKC_03531 2.39e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHFOKGKC_03532 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EHFOKGKC_03533 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EHFOKGKC_03534 4.47e-18 - - - S - - - Uncharacterized protein YkpC
EHFOKGKC_03535 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EHFOKGKC_03536 1.79e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHFOKGKC_03537 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHFOKGKC_03538 5.23e-50 ykoA - - - - - - -
EHFOKGKC_03539 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHFOKGKC_03540 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EHFOKGKC_03541 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EHFOKGKC_03542 6.81e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_03543 2.98e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EHFOKGKC_03544 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_03545 3.37e-238 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHFOKGKC_03546 4.64e-140 yknW - - S - - - Yip1 domain
EHFOKGKC_03547 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHFOKGKC_03548 2.92e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EHFOKGKC_03549 2.64e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EHFOKGKC_03550 4.6e-308 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EHFOKGKC_03551 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHFOKGKC_03552 4.05e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EHFOKGKC_03553 2.53e-218 yknT - - - ko:K06437 - ko00000 -
EHFOKGKC_03554 7.46e-127 rok - - K - - - Repressor of ComK
EHFOKGKC_03555 2.62e-100 ykuV - - CO - - - thiol-disulfide
EHFOKGKC_03556 8.56e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EHFOKGKC_03557 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
EHFOKGKC_03558 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EHFOKGKC_03559 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EHFOKGKC_03560 5.1e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
EHFOKGKC_03561 2.98e-214 ykuO - - - - - - -
EHFOKGKC_03562 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
EHFOKGKC_03563 1.32e-215 ccpC - - K - - - Transcriptional regulator
EHFOKGKC_03564 8.55e-99 ykuL - - S - - - CBS domain
EHFOKGKC_03565 3.09e-35 ykzF - - S - - - Antirepressor AbbA
EHFOKGKC_03566 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
EHFOKGKC_03567 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
EHFOKGKC_03568 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
EHFOKGKC_03570 3.54e-180 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHFOKGKC_03571 6.6e-200 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EHFOKGKC_03572 8.88e-117 ykuD - - S - - - protein conserved in bacteria
EHFOKGKC_03573 7.96e-309 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03574 5.07e-108 ykyB - - S - - - YkyB-like protein
EHFOKGKC_03575 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EHFOKGKC_03576 6.38e-15 - - - - - - - -
EHFOKGKC_03577 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHFOKGKC_03578 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_03579 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHFOKGKC_03580 2.78e-160 ykwD - - J - - - protein with SCP PR1 domains
EHFOKGKC_03581 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EHFOKGKC_03582 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHFOKGKC_03583 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EHFOKGKC_03584 1.04e-49 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EHFOKGKC_03585 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHFOKGKC_03586 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EHFOKGKC_03587 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_03588 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EHFOKGKC_03589 1.01e-224 ykvZ - - K - - - Transcriptional regulator
EHFOKGKC_03591 4.04e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHFOKGKC_03592 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHFOKGKC_03593 2.1e-114 stoA - - CO - - - thiol-disulfide
EHFOKGKC_03594 1.54e-305 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHFOKGKC_03595 1.45e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EHFOKGKC_03596 4.16e-38 - - - - - - - -
EHFOKGKC_03597 2.22e-34 ykvS - - S - - - protein conserved in bacteria
EHFOKGKC_03598 2.54e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
EHFOKGKC_03599 0.0 - - - S - - - AIPR protein
EHFOKGKC_03600 4.26e-169 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHFOKGKC_03601 1.27e-78 - - - K - - - HxlR-like helix-turn-helix
EHFOKGKC_03602 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHFOKGKC_03603 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EHFOKGKC_03604 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EHFOKGKC_03605 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHFOKGKC_03606 1.38e-255 - - - - - - - -
EHFOKGKC_03607 6.6e-233 ykvI - - S - - - membrane
EHFOKGKC_03608 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EHFOKGKC_03609 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHFOKGKC_03610 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHFOKGKC_03611 1.36e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EHFOKGKC_03612 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHFOKGKC_03614 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EHFOKGKC_03615 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EHFOKGKC_03616 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EHFOKGKC_03617 2.73e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EHFOKGKC_03618 1.8e-291 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHFOKGKC_03619 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHFOKGKC_03620 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EHFOKGKC_03621 1.22e-248 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EHFOKGKC_03623 2.65e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHFOKGKC_03624 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_03625 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EHFOKGKC_03626 3.07e-32 ykzE - - - - - - -
EHFOKGKC_03627 3.5e-147 - - - S - - - Protein of unknown function (DUF421)
EHFOKGKC_03628 7.33e-306 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EHFOKGKC_03629 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EHFOKGKC_03630 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
EHFOKGKC_03631 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EHFOKGKC_03632 2.53e-250 ykrI - - S - - - Anti-sigma factor N-terminus
EHFOKGKC_03633 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHFOKGKC_03634 2.05e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EHFOKGKC_03635 1.43e-131 ykoX - - S - - - membrane-associated protein
EHFOKGKC_03636 5.68e-201 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHFOKGKC_03637 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EHFOKGKC_03638 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
EHFOKGKC_03639 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EHFOKGKC_03640 5.25e-37 ykoL - - - - - - -
EHFOKGKC_03641 1.11e-23 - - - - - - - -
EHFOKGKC_03642 1.23e-69 tnrA - - K - - - transcriptional
EHFOKGKC_03643 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EHFOKGKC_03645 5.38e-311 ydhD - - M - - - Glycosyl hydrolase
EHFOKGKC_03646 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EHFOKGKC_03647 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHFOKGKC_03648 5.36e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EHFOKGKC_03649 5.2e-189 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHFOKGKC_03650 1.74e-224 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHFOKGKC_03651 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHFOKGKC_03652 7.47e-154 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EHFOKGKC_03653 1.39e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03654 1.13e-180 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
EHFOKGKC_03655 2.48e-275 - - - M - - - Glycosyl transferase family 2
EHFOKGKC_03657 9.03e-80 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHFOKGKC_03658 1.58e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
EHFOKGKC_03659 2.43e-111 ohrR - - K - - - COG1846 Transcriptional regulators
EHFOKGKC_03660 3.98e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
EHFOKGKC_03661 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHFOKGKC_03662 7.52e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHFOKGKC_03663 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EHFOKGKC_03664 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHFOKGKC_03665 4.09e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHFOKGKC_03666 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHFOKGKC_03667 8.79e-120 ykhA - - I - - - Acyl-CoA hydrolase
EHFOKGKC_03668 1.71e-203 ykgA - - E - - - Amidinotransferase
EHFOKGKC_03669 1.46e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EHFOKGKC_03670 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_03671 3.94e-220 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHFOKGKC_03672 1.06e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHFOKGKC_03673 1.14e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EHFOKGKC_03674 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHFOKGKC_03675 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_03676 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_03677 1.39e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHFOKGKC_03678 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EHFOKGKC_03680 0.0 yubD - - P - - - Major Facilitator Superfamily
EHFOKGKC_03681 3.91e-278 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHFOKGKC_03683 3.15e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHFOKGKC_03684 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHFOKGKC_03685 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHFOKGKC_03686 9.38e-312 steT - - E ko:K03294 - ko00000 amino acid
EHFOKGKC_03687 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EHFOKGKC_03688 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
EHFOKGKC_03689 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EHFOKGKC_03690 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EHFOKGKC_03691 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHFOKGKC_03692 4.7e-52 xhlB - - S - - - SPP1 phage holin
EHFOKGKC_03693 1.11e-50 xhlA - - S - - - Haemolysin XhlA
EHFOKGKC_03694 3.52e-175 xepA - - - - - - -
EHFOKGKC_03695 5.6e-41 xkdX - - - - - - -
EHFOKGKC_03697 2.43e-229 - - - - - - - -
EHFOKGKC_03698 5.16e-37 - - - - - - - -
EHFOKGKC_03699 2.48e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EHFOKGKC_03700 5.34e-213 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EHFOKGKC_03701 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
EHFOKGKC_03702 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
EHFOKGKC_03703 1.87e-206 xkdQ - - G - - - NLP P60 protein
EHFOKGKC_03704 1.88e-144 xkdP - - S - - - Lysin motif
EHFOKGKC_03705 2.04e-284 xkdO - - L - - - Transglycosylase SLT domain
EHFOKGKC_03706 4.33e-27 - - - - - - - -
EHFOKGKC_03707 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EHFOKGKC_03708 8.21e-97 xkdM - - S - - - Phage tail tube protein
EHFOKGKC_03709 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
EHFOKGKC_03710 1.57e-20 - - - - - - - -
EHFOKGKC_03711 4.28e-74 xkdJ - - - - - - -
EHFOKGKC_03712 6.9e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EHFOKGKC_03713 2.35e-55 - - - S - - - Domain of unknown function (DUF3599)
EHFOKGKC_03714 2.17e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
EHFOKGKC_03715 8.3e-203 xkdG - - S - - - Phage capsid family
EHFOKGKC_03716 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
EHFOKGKC_03717 1.26e-302 xkdE3 - - S - - - portal protein
EHFOKGKC_03718 9.59e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EHFOKGKC_03719 4.8e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EHFOKGKC_03720 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHFOKGKC_03724 7.52e-197 xkdC - - L - - - Bacterial dnaA protein
EHFOKGKC_03726 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
EHFOKGKC_03727 1.87e-144 xkdA - - E - - - IrrE N-terminal-like domain
EHFOKGKC_03728 7.99e-189 yjqC - - P ko:K07217 - ko00000 Catalase
EHFOKGKC_03729 8.47e-141 yjqB - - S - - - phage-related replication protein
EHFOKGKC_03730 9.51e-81 yjqA - - S - - - Bacterial PH domain
EHFOKGKC_03731 2.37e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHFOKGKC_03733 1.55e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHFOKGKC_03734 1.02e-103 yjoA - - S - - - DinB family
EHFOKGKC_03735 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EHFOKGKC_03736 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EHFOKGKC_03737 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EHFOKGKC_03738 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EHFOKGKC_03739 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
EHFOKGKC_03740 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EHFOKGKC_03741 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHFOKGKC_03742 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EHFOKGKC_03743 2.1e-119 yjlB - - S - - - Cupin domain
EHFOKGKC_03744 5.01e-228 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EHFOKGKC_03745 1.86e-167 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHFOKGKC_03746 8e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EHFOKGKC_03747 4.13e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHFOKGKC_03748 1e-39 - - - - - - - -
EHFOKGKC_03749 1.53e-286 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHFOKGKC_03750 1.54e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHFOKGKC_03751 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
EHFOKGKC_03752 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EHFOKGKC_03753 3.5e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
EHFOKGKC_03754 1.08e-92 yjgA - - T - - - Protein of unknown function (DUF2809)
EHFOKGKC_03755 2.23e-30 yjfB - - S - - - Putative motility protein
EHFOKGKC_03757 8.28e-135 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EHFOKGKC_03760 2.06e-161 - - - S - - - Haloacid dehalogenase-like hydrolase
EHFOKGKC_03761 5.89e-179 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHFOKGKC_03762 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHFOKGKC_03763 2.56e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHFOKGKC_03764 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHFOKGKC_03765 1.1e-276 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHFOKGKC_03766 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHFOKGKC_03767 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EHFOKGKC_03768 6.62e-282 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EHFOKGKC_03769 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_03770 1.26e-135 yfjF - - EGP - - - Belongs to the major facilitator superfamily
EHFOKGKC_03771 1.19e-162 yfjF - - EGP - - - Belongs to the major facilitator superfamily
EHFOKGKC_03772 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EHFOKGKC_03773 8.5e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EHFOKGKC_03775 8.95e-94 - - - E - - - phosphoribosylanthranilate isomerase activity
EHFOKGKC_03776 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
EHFOKGKC_03779 1.46e-28 - - - - - - - -
EHFOKGKC_03780 2.07e-51 - - - - - - - -
EHFOKGKC_03782 3.43e-106 - - - - - - - -
EHFOKGKC_03783 3.68e-23 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
EHFOKGKC_03784 5.51e-42 - - - S - - - Bacterial EndoU nuclease
EHFOKGKC_03785 1.18e-72 - - - - - - - -
EHFOKGKC_03786 8.52e-34 - - - S - - - YolD-like protein
EHFOKGKC_03787 3.03e-62 - - - - - - - -
EHFOKGKC_03789 5.58e-59 - - - - - - - -
EHFOKGKC_03796 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHFOKGKC_03797 1.38e-82 hxlR - - K - - - transcriptional
EHFOKGKC_03798 3.14e-139 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EHFOKGKC_03799 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EHFOKGKC_03800 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
EHFOKGKC_03801 1.95e-90 nin - - S - - - Competence protein J (ComJ)
EHFOKGKC_03802 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHFOKGKC_03803 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
EHFOKGKC_03804 2.67e-96 yckC - - S - - - membrane
EHFOKGKC_03805 1.29e-283 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHFOKGKC_03806 2.75e-287 yciC - - S - - - GTPases (G3E family)
EHFOKGKC_03807 9.53e-284 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHFOKGKC_03808 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EHFOKGKC_03809 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHFOKGKC_03810 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHFOKGKC_03811 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EHFOKGKC_03812 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHFOKGKC_03813 4.73e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EHFOKGKC_03814 1.17e-289 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EHFOKGKC_03815 2.55e-275 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHFOKGKC_03816 3.12e-45 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHFOKGKC_03817 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHFOKGKC_03818 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHFOKGKC_03819 8.73e-189 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EHFOKGKC_03820 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EHFOKGKC_03821 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHFOKGKC_03822 3.2e-302 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHFOKGKC_03823 1.34e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
EHFOKGKC_03824 3.74e-138 tmrB - - S - - - AAA domain
EHFOKGKC_03825 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
EHFOKGKC_03826 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EHFOKGKC_03827 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EHFOKGKC_03828 4.47e-312 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHFOKGKC_03829 6.95e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EHFOKGKC_03830 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
EHFOKGKC_03831 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHFOKGKC_03832 0.0 mdr - - EGP - - - the major facilitator superfamily
EHFOKGKC_03833 9.37e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EHFOKGKC_03834 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EHFOKGKC_03835 4.41e-106 ycgB - - - - - - -
EHFOKGKC_03836 9.35e-293 ycgA - - S - - - Membrane
EHFOKGKC_03837 1.13e-270 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EHFOKGKC_03838 9.95e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHFOKGKC_03839 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHFOKGKC_03840 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EHFOKGKC_03841 4.48e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EHFOKGKC_03842 1.17e-246 yceH - - P - - - Belongs to the TelA family
EHFOKGKC_03843 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EHFOKGKC_03844 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EHFOKGKC_03845 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHFOKGKC_03846 2.98e-135 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHFOKGKC_03847 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EHFOKGKC_03848 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHFOKGKC_03849 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EHFOKGKC_03850 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EHFOKGKC_03851 2.99e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EHFOKGKC_03852 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHFOKGKC_03853 1.05e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EHFOKGKC_03854 8.19e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EHFOKGKC_03855 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHFOKGKC_03856 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_03857 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHFOKGKC_03858 1.38e-227 ycdA - - S - - - Domain of unknown function (DUF5105)
EHFOKGKC_03859 1.54e-218 yccK - - C - - - Aldo keto reductase
EHFOKGKC_03860 4.81e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
EHFOKGKC_03861 5.23e-144 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHFOKGKC_03862 3.55e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EHFOKGKC_03863 2.19e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHFOKGKC_03864 1.61e-309 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHFOKGKC_03865 1.65e-264 ycbU - - E - - - Selenocysteine lyase
EHFOKGKC_03866 5.93e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHFOKGKC_03867 2.74e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHFOKGKC_03868 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHFOKGKC_03869 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EHFOKGKC_03870 1.05e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EHFOKGKC_03871 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
EHFOKGKC_03872 1.54e-73 ydfQ - - CO - - - Thioredoxin
EHFOKGKC_03873 9.37e-83 ydfP - - S ko:K15977 - ko00000 DoxX
EHFOKGKC_03874 1.24e-234 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHFOKGKC_03875 1.15e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EHFOKGKC_03876 2.59e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHFOKGKC_03877 6.9e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EHFOKGKC_03878 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EHFOKGKC_03879 2.65e-280 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHFOKGKC_03880 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHFOKGKC_03881 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHFOKGKC_03882 1.02e-230 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EHFOKGKC_03883 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHFOKGKC_03884 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHFOKGKC_03885 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHFOKGKC_03886 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EHFOKGKC_03887 2.13e-55 ybfN - - - - - - -
EHFOKGKC_03888 3.05e-194 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EHFOKGKC_03889 8.6e-113 ybfM - - S - - - SNARE associated Golgi protein
EHFOKGKC_03890 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHFOKGKC_03891 7.96e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHFOKGKC_03892 6.1e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EHFOKGKC_03893 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
EHFOKGKC_03894 2.44e-45 - - - - - - - -
EHFOKGKC_03895 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EHFOKGKC_03897 3.34e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EHFOKGKC_03898 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
EHFOKGKC_03899 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EHFOKGKC_03900 3.73e-207 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EHFOKGKC_03901 5.43e-54 - - - M - - - PFAM Glycosyl transferase family 2
EHFOKGKC_03902 0.0 ybeC - - E - - - amino acid
EHFOKGKC_03903 7.84e-55 ybyB - - - - - - -
EHFOKGKC_03904 7.51e-146 yqeB - - - - - - -
EHFOKGKC_03905 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EHFOKGKC_03906 3.52e-101 - - - S - - - Domain of unknown function (DUF4879)
EHFOKGKC_03907 6.02e-51 - - - Q - - - Dimerisation domain
EHFOKGKC_03908 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
EHFOKGKC_03909 1.45e-120 - - - Q - - - Flavin containing amine oxidoreductase
EHFOKGKC_03910 0.0 - - - Q - - - Polyketide synthase modules and related proteins
EHFOKGKC_03911 0.0 - - - Q - - - Beta-ketoacyl synthase
EHFOKGKC_03912 1.92e-150 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
EHFOKGKC_03913 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
EHFOKGKC_03914 0.0 - - - Q ko:K15654 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 TIGRFAM amino acid adenylation domain
EHFOKGKC_03915 2.04e-66 - - - L - - - transposase activity
EHFOKGKC_03917 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_03918 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_03919 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHFOKGKC_03920 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHFOKGKC_03921 5.63e-316 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHFOKGKC_03924 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHFOKGKC_03925 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHFOKGKC_03926 7.04e-42 - - - S - - - GlpM protein
EHFOKGKC_03927 3.63e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EHFOKGKC_03928 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHFOKGKC_03929 2.1e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHFOKGKC_03930 2.28e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EHFOKGKC_03931 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHFOKGKC_03932 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHFOKGKC_03933 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHFOKGKC_03934 1.3e-34 yqzJ - - - - - - -
EHFOKGKC_03935 2.05e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHFOKGKC_03936 8.71e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EHFOKGKC_03937 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHFOKGKC_03938 7.7e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EHFOKGKC_03940 9.08e-124 yqjB - - S - - - protein conserved in bacteria
EHFOKGKC_03941 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EHFOKGKC_03942 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHFOKGKC_03943 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHFOKGKC_03944 2.38e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHFOKGKC_03945 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
EHFOKGKC_03946 4.26e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHFOKGKC_03947 7.25e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHFOKGKC_03948 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHFOKGKC_03949 2.75e-222 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHFOKGKC_03950 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHFOKGKC_03951 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EHFOKGKC_03952 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHFOKGKC_03953 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EHFOKGKC_03954 0.0 bkdR - - KT - - - Transcriptional regulator
EHFOKGKC_03955 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EHFOKGKC_03956 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHFOKGKC_03957 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EHFOKGKC_03958 4.18e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHFOKGKC_03959 1.51e-261 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EHFOKGKC_03960 2.41e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EHFOKGKC_03961 1.95e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHFOKGKC_03962 3.83e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHFOKGKC_03963 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EHFOKGKC_03965 1.13e-130 - - - P - - - Probably functions as a manganese efflux pump
EHFOKGKC_03966 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
EHFOKGKC_03968 3.23e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EHFOKGKC_03971 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHFOKGKC_03972 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EHFOKGKC_03973 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EHFOKGKC_03974 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EHFOKGKC_03975 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EHFOKGKC_03976 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EHFOKGKC_03977 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHFOKGKC_03978 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHFOKGKC_03979 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHFOKGKC_03980 1.95e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHFOKGKC_03981 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHFOKGKC_03982 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHFOKGKC_03983 1.36e-87 yqhY - - S - - - protein conserved in bacteria
EHFOKGKC_03984 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EHFOKGKC_03985 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EHFOKGKC_03986 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EHFOKGKC_03987 2.86e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EHFOKGKC_03988 6.07e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EHFOKGKC_03989 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EHFOKGKC_03990 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EHFOKGKC_03991 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EHFOKGKC_03992 1.7e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EHFOKGKC_03993 1.04e-219 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EHFOKGKC_03994 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EHFOKGKC_03995 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHFOKGKC_03996 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHFOKGKC_03997 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
EHFOKGKC_03998 1.04e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
EHFOKGKC_03999 7.65e-83 yqhP - - - - - - -
EHFOKGKC_04000 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHFOKGKC_04001 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EHFOKGKC_04002 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EHFOKGKC_04003 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EHFOKGKC_04004 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHFOKGKC_04005 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHFOKGKC_04006 1.92e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EHFOKGKC_04007 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHFOKGKC_04008 3.57e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
EHFOKGKC_04009 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EHFOKGKC_04010 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EHFOKGKC_04011 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EHFOKGKC_04012 1.89e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EHFOKGKC_04013 5.44e-155 yqxM - - - ko:K19433 - ko00000 -
EHFOKGKC_04014 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
EHFOKGKC_04015 2e-36 yqzE - - S - - - YqzE-like protein
EHFOKGKC_04016 4.9e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EHFOKGKC_04017 1.82e-84 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EHFOKGKC_04018 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EHFOKGKC_04019 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
EHFOKGKC_04020 9e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EHFOKGKC_04021 4.65e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EHFOKGKC_04022 1.1e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHFOKGKC_04023 6.43e-239 yqxL - - P - - - Mg2 transporter protein
EHFOKGKC_04024 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHFOKGKC_04025 2.05e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHFOKGKC_04027 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EHFOKGKC_04028 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EHFOKGKC_04029 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EHFOKGKC_04030 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
EHFOKGKC_04031 6.04e-65 dglA - - S - - - Thiamine-binding protein
EHFOKGKC_04032 1.55e-255 yqgU - - - - - - -
EHFOKGKC_04033 2.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EHFOKGKC_04034 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EHFOKGKC_04035 1.84e-38 yqgQ - - S - - - Protein conserved in bacteria
EHFOKGKC_04036 1.21e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHFOKGKC_04037 5.38e-11 yqgO - - - - - - -
EHFOKGKC_04038 2.03e-124 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHFOKGKC_04039 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHFOKGKC_04040 3.42e-68 yqzD - - - - - - -
EHFOKGKC_04041 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHFOKGKC_04042 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHFOKGKC_04043 2.91e-186 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHFOKGKC_04044 2.39e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EHFOKGKC_04045 3.53e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EHFOKGKC_04046 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)