ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MKBDJGCF_00002 1e-66 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
MKBDJGCF_00006 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MKBDJGCF_00007 1.29e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MKBDJGCF_00008 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
MKBDJGCF_00009 9.83e-33 - - - S - - - Protein of unknown function (DUF3212)
MKBDJGCF_00010 9.68e-231 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MKBDJGCF_00011 1.34e-259 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MKBDJGCF_00012 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKBDJGCF_00013 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MKBDJGCF_00014 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MKBDJGCF_00015 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKBDJGCF_00016 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_00017 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MKBDJGCF_00018 3.69e-165 yfmS - - NT - - - chemotaxis protein
MKBDJGCF_00019 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKBDJGCF_00020 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
MKBDJGCF_00021 4.78e-272 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_00022 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MKBDJGCF_00023 7.97e-273 yfnE - - S - - - Glycosyltransferase like family 2
MKBDJGCF_00024 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MKBDJGCF_00025 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MKBDJGCF_00026 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MKBDJGCF_00027 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MKBDJGCF_00029 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MKBDJGCF_00030 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
MKBDJGCF_00031 3.35e-246 yetM - - CH - - - FAD binding domain
MKBDJGCF_00032 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_00033 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MKBDJGCF_00034 2.59e-73 - - - H - - - riboflavin kinase activity
MKBDJGCF_00035 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
MKBDJGCF_00036 1.49e-67 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKBDJGCF_00037 7.59e-102 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKBDJGCF_00038 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_00039 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MKBDJGCF_00040 1.26e-147 yetF - - S - - - membrane
MKBDJGCF_00042 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
MKBDJGCF_00043 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MKBDJGCF_00044 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
MKBDJGCF_00045 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MKBDJGCF_00046 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MKBDJGCF_00048 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
MKBDJGCF_00049 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
MKBDJGCF_00050 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
MKBDJGCF_00051 2.48e-66 - - - S - - - Protein of unknown function, DUF600
MKBDJGCF_00052 2.35e-73 - - - S - - - Protein of unknown function, DUF600
MKBDJGCF_00053 5.92e-51 - - - S - - - Protein of unknown function, DUF600
MKBDJGCF_00054 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MKBDJGCF_00055 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MKBDJGCF_00056 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MKBDJGCF_00057 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKBDJGCF_00058 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKBDJGCF_00059 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKBDJGCF_00060 1.01e-189 yerO - - K - - - Transcriptional regulator
MKBDJGCF_00061 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKBDJGCF_00062 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKBDJGCF_00063 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKBDJGCF_00064 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKBDJGCF_00065 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MKBDJGCF_00066 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MKBDJGCF_00067 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MKBDJGCF_00068 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKBDJGCF_00069 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MKBDJGCF_00070 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKBDJGCF_00071 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MKBDJGCF_00072 2.03e-67 yerC - - S - - - protein conserved in bacteria
MKBDJGCF_00073 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MKBDJGCF_00074 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MKBDJGCF_00075 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
MKBDJGCF_00076 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MKBDJGCF_00077 4.48e-81 - - - K - - - helix_turn_helix ASNC type
MKBDJGCF_00078 7.41e-294 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MKBDJGCF_00079 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MKBDJGCF_00080 3.89e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKBDJGCF_00081 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MKBDJGCF_00082 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKBDJGCF_00083 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKBDJGCF_00084 6.14e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKBDJGCF_00085 8.96e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKBDJGCF_00086 2.2e-162 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MKBDJGCF_00087 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKBDJGCF_00088 2.42e-282 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKBDJGCF_00089 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKBDJGCF_00090 7.68e-39 yebG - - S - - - NETI protein
MKBDJGCF_00091 7.62e-120 yebE - - S - - - UPF0316 protein
MKBDJGCF_00093 1.34e-162 yebC - - M - - - Membrane
MKBDJGCF_00094 1.01e-268 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MKBDJGCF_00095 1.51e-313 - - - S - - - Domain of unknown function (DUF4179)
MKBDJGCF_00096 3.03e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_00097 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MKBDJGCF_00098 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MKBDJGCF_00099 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MKBDJGCF_00100 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MKBDJGCF_00101 3.12e-192 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKBDJGCF_00102 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_00103 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MKBDJGCF_00104 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
MKBDJGCF_00106 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MKBDJGCF_00107 7.91e-83 ydjM - - M - - - Lytic transglycolase
MKBDJGCF_00108 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MKBDJGCF_00109 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_00110 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
MKBDJGCF_00111 0.0 oatA - - I - - - Acyltransferase family
MKBDJGCF_00112 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MKBDJGCF_00113 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MKBDJGCF_00114 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKBDJGCF_00115 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MKBDJGCF_00116 1.21e-39 yjdJ - - S - - - Domain of unknown function (DUF4306)
MKBDJGCF_00117 1.36e-217 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MKBDJGCF_00118 6.05e-290 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MKBDJGCF_00119 6.58e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MKBDJGCF_00120 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MKBDJGCF_00121 2.21e-81 - - - - - - - -
MKBDJGCF_00123 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
MKBDJGCF_00124 1.96e-22 - - - - - - - -
MKBDJGCF_00125 1.87e-63 - - - V - - - Abortive infection bacteriophage resistance protein
MKBDJGCF_00126 9.33e-52 - - - - - - - -
MKBDJGCF_00127 3.41e-22 - - - - - - - -
MKBDJGCF_00128 3.37e-86 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_00129 1.36e-77 - - - S - - - Pfam:Phage_holin_4_1
MKBDJGCF_00133 1.56e-244 - - - L - - - Phage minor structural protein
MKBDJGCF_00135 2.31e-70 - - - S - - - Phage-related minor tail protein
MKBDJGCF_00136 1.05e-189 - - - - - - - -
MKBDJGCF_00138 3.23e-44 - - - S - - - Phage tail tube protein
MKBDJGCF_00139 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
MKBDJGCF_00140 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MKBDJGCF_00141 5.19e-38 - - - S - - - Phage head-tail joining protein
MKBDJGCF_00142 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
MKBDJGCF_00145 1.85e-61 - - - S - - - viral capsid
MKBDJGCF_00146 3.82e-56 - - - S - - - Phage minor structural protein GP20
MKBDJGCF_00148 1.53e-116 - - - S - - - Phage Mu protein F like protein
MKBDJGCF_00149 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
MKBDJGCF_00150 9.66e-225 - - - S - - - Pfam:Terminase_3C
MKBDJGCF_00151 1.99e-47 yqaS - - L - - - DNA packaging
MKBDJGCF_00152 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_00153 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MKBDJGCF_00154 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MKBDJGCF_00155 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKBDJGCF_00156 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKBDJGCF_00157 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MKBDJGCF_00159 2.92e-109 - - - L - - - Phage integrase family
MKBDJGCF_00169 1.13e-20 - - - - - - - -
MKBDJGCF_00170 2.83e-74 - - - - - - - -
MKBDJGCF_00172 5.62e-140 - - - L ko:K02315 - ko00000,ko03032 DNA-dependent DNA replication
MKBDJGCF_00176 6.41e-181 - - - L - - - DnaB-like helicase C terminal domain
MKBDJGCF_00177 6.62e-176 - - - L - - - Toprim-like
MKBDJGCF_00178 2.1e-07 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_00179 2.11e-12 - - - S - - - Cro/C1-type HTH DNA-binding domain
MKBDJGCF_00184 1.9e-102 - - - - - - - -
MKBDJGCF_00185 1.77e-62 - - - - - - - -
MKBDJGCF_00186 2.06e-08 - - - - - - - -
MKBDJGCF_00188 0.0 - - - L - - - DNA polymerase family A
MKBDJGCF_00190 6.08e-206 - - - - - - - -
MKBDJGCF_00191 3.31e-34 - - - - - - - -
MKBDJGCF_00192 6.96e-21 - 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Crossover junction endodeoxyribonuclease RuvC
MKBDJGCF_00196 2.45e-57 - - - F - - - Belongs to the NrdI family
MKBDJGCF_00197 6.93e-152 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKBDJGCF_00198 0.000318 - - - S - - - Transcriptional regulator
MKBDJGCF_00199 1.2e-250 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKBDJGCF_00201 8.39e-196 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKBDJGCF_00202 1.95e-77 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
MKBDJGCF_00204 1.07e-35 - - - S - - - AP2 domain
MKBDJGCF_00205 5.57e-125 - 2.1.1.148 - F ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 ko00000,ko00001,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
MKBDJGCF_00206 6.45e-47 - - - S - - - protein conserved in bacteria
MKBDJGCF_00207 2.08e-47 - - - - - - - -
MKBDJGCF_00208 1.39e-78 - - - H - - - dephospho-CoA kinase activity
MKBDJGCF_00209 1.07e-173 - - - S - - - C-5 cytosine-specific DNA methylase
MKBDJGCF_00211 2.17e-56 - - - K - - - Sigma-70, region 4
MKBDJGCF_00212 1.33e-44 - - - - - - - -
MKBDJGCF_00213 7.23e-11 - - - - - - - -
MKBDJGCF_00215 5.78e-150 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
MKBDJGCF_00217 7.61e-32 - - - - - - - -
MKBDJGCF_00218 2.79e-62 - - - - - - - -
MKBDJGCF_00222 6.8e-136 - - - M - - - Right handed beta helix region
MKBDJGCF_00223 3.13e-68 yjqB - - S - - - Pfam:DUF867
MKBDJGCF_00224 2.71e-39 - - - K - - - Cro/C1-type HTH DNA-binding domain
MKBDJGCF_00225 2.32e-50 - - GT2 S ko:K19425,ko:K19427 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_00230 4.77e-50 - - - - - - - -
MKBDJGCF_00233 6.79e-29 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
MKBDJGCF_00234 1.71e-61 - - - L - - - Phage terminase, small subunit
MKBDJGCF_00235 0.0 - - - S - - - Terminase
MKBDJGCF_00236 1.24e-281 - - - S - - - Phage portal protein
MKBDJGCF_00237 5.47e-156 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MKBDJGCF_00238 1.06e-186 - - - S - - - Phage capsid family
MKBDJGCF_00239 9.8e-43 - - - N - - - domain, Protein
MKBDJGCF_00240 4.64e-35 - - - S - - - Phage gp6-like head-tail connector protein
MKBDJGCF_00241 7.49e-47 - - - S - - - Phage head-tail joining protein
MKBDJGCF_00243 1.21e-32 - - - - - - - -
MKBDJGCF_00244 4.26e-90 - - - N - - - phage major tail protein, phi13 family
MKBDJGCF_00245 5.64e-44 - - - - - - - -
MKBDJGCF_00246 1.64e-142 - - - D - - - Phage tail tape measure protein
MKBDJGCF_00247 3.41e-139 - - - S - - - Phage tail protein
MKBDJGCF_00248 3.62e-238 - - - L - - - Prophage endopeptidase tail
MKBDJGCF_00249 0.0 - - - M - - - Pectate lyase superfamily protein
MKBDJGCF_00250 3.32e-100 - - - S - - - Domain of unknown function (DUF2479)
MKBDJGCF_00253 1.66e-39 - - - S - - - BhlA holin family
MKBDJGCF_00254 5.19e-188 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MKBDJGCF_00255 1.04e-45 - - - S - - - Bacteriophage A118-like holin, Hol118
MKBDJGCF_00258 8.37e-29 - - - S - - - protein disulfide oxidoreductase activity
MKBDJGCF_00260 2.97e-159 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
MKBDJGCF_00261 1.73e-83 - - - - - - - -
MKBDJGCF_00262 1.47e-17 - - - K ko:K07727 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MKBDJGCF_00263 5.65e-128 - - - K - - - Helix-turn-helix domain
MKBDJGCF_00266 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MKBDJGCF_00267 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MKBDJGCF_00268 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKBDJGCF_00269 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKBDJGCF_00270 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKBDJGCF_00271 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKBDJGCF_00272 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKBDJGCF_00273 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
MKBDJGCF_00274 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKBDJGCF_00275 2.7e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKBDJGCF_00276 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MKBDJGCF_00277 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKBDJGCF_00278 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MKBDJGCF_00279 3.63e-110 ysxD - - - - - - -
MKBDJGCF_00280 1.61e-310 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKBDJGCF_00281 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MKBDJGCF_00282 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MKBDJGCF_00283 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MKBDJGCF_00284 1.7e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MKBDJGCF_00285 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MKBDJGCF_00286 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MKBDJGCF_00287 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKBDJGCF_00288 3.61e-34 - - - - - - - -
MKBDJGCF_00289 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKBDJGCF_00290 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MKBDJGCF_00291 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MKBDJGCF_00292 2.51e-192 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MKBDJGCF_00293 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MKBDJGCF_00294 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MKBDJGCF_00295 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MKBDJGCF_00296 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MKBDJGCF_00297 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MKBDJGCF_00298 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKBDJGCF_00299 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MKBDJGCF_00300 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MKBDJGCF_00301 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MKBDJGCF_00302 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MKBDJGCF_00303 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MKBDJGCF_00304 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MKBDJGCF_00305 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MKBDJGCF_00306 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKBDJGCF_00307 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MKBDJGCF_00308 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MKBDJGCF_00309 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MKBDJGCF_00310 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MKBDJGCF_00311 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MKBDJGCF_00312 3.89e-182 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MKBDJGCF_00313 2.53e-264 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKBDJGCF_00314 2.41e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MKBDJGCF_00315 1.26e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKBDJGCF_00317 1.93e-117 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MKBDJGCF_00318 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKBDJGCF_00319 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKBDJGCF_00320 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
MKBDJGCF_00321 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKBDJGCF_00322 3.9e-291 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKBDJGCF_00323 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MKBDJGCF_00324 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
MKBDJGCF_00325 1.16e-133 yrbG - - S - - - membrane
MKBDJGCF_00326 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_00327 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
MKBDJGCF_00328 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKBDJGCF_00329 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MKBDJGCF_00330 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MKBDJGCF_00331 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MKBDJGCF_00332 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKBDJGCF_00333 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKBDJGCF_00334 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKBDJGCF_00335 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MKBDJGCF_00338 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MKBDJGCF_00339 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKBDJGCF_00340 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MKBDJGCF_00341 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MKBDJGCF_00342 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_00343 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MKBDJGCF_00344 8.02e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKBDJGCF_00345 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
MKBDJGCF_00346 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKBDJGCF_00347 7.39e-100 yrrD - - S - - - protein conserved in bacteria
MKBDJGCF_00348 8.4e-42 yrzR - - - - - - -
MKBDJGCF_00349 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
MKBDJGCF_00350 1.21e-135 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKBDJGCF_00351 7.62e-138 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKBDJGCF_00352 1.67e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MKBDJGCF_00353 1.67e-163 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MKBDJGCF_00354 2.41e-223 yrrI - - S - - - AI-2E family transporter
MKBDJGCF_00355 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKBDJGCF_00356 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
MKBDJGCF_00357 1.11e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKBDJGCF_00358 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
MKBDJGCF_00359 1.71e-244 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKBDJGCF_00360 3.4e-146 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MKBDJGCF_00361 4.25e-220 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MKBDJGCF_00362 1.8e-310 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MKBDJGCF_00363 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MKBDJGCF_00364 5.41e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKBDJGCF_00365 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MKBDJGCF_00366 6.53e-120 yrrS - - S - - - Protein of unknown function (DUF1510)
MKBDJGCF_00367 2.53e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
MKBDJGCF_00368 3.7e-148 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MKBDJGCF_00369 6.59e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKBDJGCF_00370 8.52e-212 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MKBDJGCF_00371 6.51e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MKBDJGCF_00372 9.51e-47 yrhC - - S - - - YrhC-like protein
MKBDJGCF_00373 4.38e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
MKBDJGCF_00374 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MKBDJGCF_00375 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MKBDJGCF_00376 1.48e-178 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MKBDJGCF_00377 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MKBDJGCF_00378 2.19e-112 yrhH - - Q - - - methyltransferase
MKBDJGCF_00379 8.49e-124 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MKBDJGCF_00380 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MKBDJGCF_00381 8.7e-262 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_00382 3.47e-206 yybE - - K - - - Transcriptional regulator
MKBDJGCF_00383 1.26e-95 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKBDJGCF_00384 1.52e-211 romA - - S - - - Beta-lactamase superfamily domain
MKBDJGCF_00385 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MKBDJGCF_00386 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_00387 5.34e-217 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MKBDJGCF_00388 6.13e-151 - - - K - - - Helix-turn-helix domain, rpiR family
MKBDJGCF_00389 2.86e-178 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MKBDJGCF_00390 5.58e-179 supH - - S - - - hydrolase
MKBDJGCF_00391 2.45e-114 - - - S - - - DinB family
MKBDJGCF_00392 7.94e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_00393 6.92e-35 - - - K - - - acetyltransferase
MKBDJGCF_00394 3.71e-126 yqaC - - F - - - adenylate kinase activity
MKBDJGCF_00395 7.88e-116 - - - K - - - Transcriptional regulator PadR-like family
MKBDJGCF_00396 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MKBDJGCF_00397 1.37e-157 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_00398 2.92e-254 - - - EGP - - - Transmembrane secretion effector
MKBDJGCF_00400 7.69e-134 yqeD - - S - - - SNARE associated Golgi protein
MKBDJGCF_00401 2.21e-140 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_00402 2.3e-171 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MKBDJGCF_00403 7.74e-174 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MKBDJGCF_00405 7.28e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MKBDJGCF_00406 1.08e-269 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MKBDJGCF_00407 5.24e-195 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKBDJGCF_00408 8.62e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MKBDJGCF_00409 8.59e-133 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKBDJGCF_00410 1.13e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MKBDJGCF_00411 1.1e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKBDJGCF_00412 4.47e-174 yqeM - - Q - - - Methyltransferase
MKBDJGCF_00413 1.74e-185 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKBDJGCF_00414 3.77e-123 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MKBDJGCF_00415 8.94e-135 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MKBDJGCF_00416 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MKBDJGCF_00417 3.58e-109 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MKBDJGCF_00418 7.73e-22 - - - S - - - YqzM-like protein
MKBDJGCF_00419 8.29e-229 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MKBDJGCF_00420 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MKBDJGCF_00421 9.8e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKBDJGCF_00422 2.14e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MKBDJGCF_00423 1.17e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
MKBDJGCF_00424 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKBDJGCF_00425 1.93e-265 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MKBDJGCF_00426 1.3e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKBDJGCF_00427 2.08e-106 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKBDJGCF_00428 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MKBDJGCF_00429 4.72e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKBDJGCF_00430 7.67e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MKBDJGCF_00431 1.14e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKBDJGCF_00432 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MKBDJGCF_00433 1.4e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MKBDJGCF_00434 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MKBDJGCF_00435 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MKBDJGCF_00436 7.88e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MKBDJGCF_00437 1.22e-186 yqfA - - S - - - UPF0365 protein
MKBDJGCF_00438 1.28e-48 yqfB - - - - - - -
MKBDJGCF_00439 3.57e-61 yqfC - - S - - - sporulation protein YqfC
MKBDJGCF_00440 7.99e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MKBDJGCF_00441 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MKBDJGCF_00442 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MKBDJGCF_00443 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKBDJGCF_00444 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MKBDJGCF_00445 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKBDJGCF_00446 2.01e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKBDJGCF_00447 6e-24 - - - S - - - YqzL-like protein
MKBDJGCF_00448 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MKBDJGCF_00449 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MKBDJGCF_00450 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MKBDJGCF_00451 3.41e-144 ccpN - - K - - - CBS domain
MKBDJGCF_00452 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKBDJGCF_00453 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MKBDJGCF_00454 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKBDJGCF_00455 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKBDJGCF_00456 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MKBDJGCF_00457 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MKBDJGCF_00458 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKBDJGCF_00459 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKBDJGCF_00460 7.12e-57 yqfQ - - S - - - YqfQ-like protein
MKBDJGCF_00461 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKBDJGCF_00462 5.3e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKBDJGCF_00463 2.48e-48 yqfT - - S - - - Protein of unknown function (DUF2624)
MKBDJGCF_00464 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_00465 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MKBDJGCF_00466 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MKBDJGCF_00467 3.9e-79 yqfX - - S - - - membrane
MKBDJGCF_00468 2.3e-255 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKBDJGCF_00469 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
MKBDJGCF_00470 2.44e-164 yqgB - - S - - - Protein of unknown function (DUF1189)
MKBDJGCF_00471 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MKBDJGCF_00472 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MKBDJGCF_00473 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MKBDJGCF_00474 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MKBDJGCF_00475 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MKBDJGCF_00476 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MKBDJGCF_00477 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MKBDJGCF_00478 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKBDJGCF_00479 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKBDJGCF_00480 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKBDJGCF_00481 3.42e-68 yqzD - - - - - - -
MKBDJGCF_00482 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MKBDJGCF_00483 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKBDJGCF_00484 5.38e-11 yqgO - - - - - - -
MKBDJGCF_00485 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MKBDJGCF_00486 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
MKBDJGCF_00487 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MKBDJGCF_00488 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MKBDJGCF_00489 1.57e-239 yqgU - - - - - - -
MKBDJGCF_00490 2.02e-63 dglA - - S - - - Thiamine-binding protein
MKBDJGCF_00491 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
MKBDJGCF_00492 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MKBDJGCF_00493 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MKBDJGCF_00494 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MKBDJGCF_00496 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKBDJGCF_00497 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MKBDJGCF_00498 1.34e-231 yqxL - - P - - - Mg2 transporter protein
MKBDJGCF_00499 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKBDJGCF_00500 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MKBDJGCF_00501 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MKBDJGCF_00502 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
MKBDJGCF_00503 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MKBDJGCF_00504 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MKBDJGCF_00505 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MKBDJGCF_00506 9.56e-35 yqzE - - S - - - YqzE-like protein
MKBDJGCF_00507 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
MKBDJGCF_00508 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
MKBDJGCF_00509 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MKBDJGCF_00510 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MKBDJGCF_00511 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MKBDJGCF_00512 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MKBDJGCF_00513 1.98e-191 yqhG - - S - - - Bacterial protein YqhG of unknown function
MKBDJGCF_00514 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKBDJGCF_00515 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MKBDJGCF_00516 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKBDJGCF_00517 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKBDJGCF_00518 3.87e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MKBDJGCF_00519 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MKBDJGCF_00520 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MKBDJGCF_00521 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MKBDJGCF_00522 8.59e-80 yqhP - - - - - - -
MKBDJGCF_00523 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
MKBDJGCF_00524 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
MKBDJGCF_00525 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MKBDJGCF_00526 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKBDJGCF_00527 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
MKBDJGCF_00528 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MKBDJGCF_00529 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MKBDJGCF_00530 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MKBDJGCF_00531 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MKBDJGCF_00532 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MKBDJGCF_00533 1.74e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MKBDJGCF_00534 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MKBDJGCF_00535 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MKBDJGCF_00536 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKBDJGCF_00537 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MKBDJGCF_00538 5.53e-87 yqhY - - S - - - protein conserved in bacteria
MKBDJGCF_00539 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKBDJGCF_00540 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKBDJGCF_00541 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKBDJGCF_00542 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKBDJGCF_00543 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MKBDJGCF_00544 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKBDJGCF_00545 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MKBDJGCF_00546 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MKBDJGCF_00547 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MKBDJGCF_00548 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MKBDJGCF_00549 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MKBDJGCF_00550 4.31e-260 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKBDJGCF_00553 2.85e-266 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MKBDJGCF_00555 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
MKBDJGCF_00556 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
MKBDJGCF_00558 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MKBDJGCF_00559 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MKBDJGCF_00560 1.21e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MKBDJGCF_00561 1.53e-184 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MKBDJGCF_00562 9.37e-256 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MKBDJGCF_00563 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MKBDJGCF_00564 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MKBDJGCF_00565 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKBDJGCF_00566 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MKBDJGCF_00567 0.0 bkdR - - KT - - - Transcriptional regulator
MKBDJGCF_00568 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MKBDJGCF_00569 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MKBDJGCF_00570 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MKBDJGCF_00571 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKBDJGCF_00572 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKBDJGCF_00573 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKBDJGCF_00574 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKBDJGCF_00575 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKBDJGCF_00576 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
MKBDJGCF_00577 2.18e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MKBDJGCF_00578 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MKBDJGCF_00579 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MKBDJGCF_00580 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MKBDJGCF_00581 3.99e-118 yqjB - - S - - - protein conserved in bacteria
MKBDJGCF_00583 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MKBDJGCF_00584 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKBDJGCF_00585 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MKBDJGCF_00586 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKBDJGCF_00587 1.36e-36 yqzJ - - - - - - -
MKBDJGCF_00588 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKBDJGCF_00589 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKBDJGCF_00590 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKBDJGCF_00591 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKBDJGCF_00592 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MKBDJGCF_00593 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKBDJGCF_00594 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKBDJGCF_00595 2.42e-61 - - - S - - - GlpM protein
MKBDJGCF_00596 9.08e-202 - - - K - - - LysR substrate binding domain
MKBDJGCF_00597 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKBDJGCF_00598 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MKBDJGCF_00599 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_00600 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MKBDJGCF_00601 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MKBDJGCF_00603 5.73e-206 yueF - - S - - - transporter activity
MKBDJGCF_00605 7.27e-73 - - - S - - - YolD-like protein
MKBDJGCF_00606 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKBDJGCF_00607 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MKBDJGCF_00608 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MKBDJGCF_00609 1.16e-213 yqkA - - K - - - GrpB protein
MKBDJGCF_00610 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
MKBDJGCF_00611 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
MKBDJGCF_00612 2.61e-213 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MKBDJGCF_00613 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
MKBDJGCF_00614 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MKBDJGCF_00615 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
MKBDJGCF_00616 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MKBDJGCF_00617 1.43e-271 yqxK - - L - - - DNA helicase
MKBDJGCF_00618 2.32e-75 ansR - - K - - - Transcriptional regulator
MKBDJGCF_00619 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MKBDJGCF_00620 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MKBDJGCF_00621 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MKBDJGCF_00622 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MKBDJGCF_00623 5.05e-33 - - - - - - - -
MKBDJGCF_00624 2.87e-43 yqkK - - - - - - -
MKBDJGCF_00625 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MKBDJGCF_00626 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MKBDJGCF_00627 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MKBDJGCF_00628 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MKBDJGCF_00629 1.31e-289 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKBDJGCF_00630 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKBDJGCF_00631 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKBDJGCF_00632 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MKBDJGCF_00633 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MKBDJGCF_00634 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_00635 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MKBDJGCF_00636 1.56e-89 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MKBDJGCF_00637 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MKBDJGCF_00638 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MKBDJGCF_00639 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MKBDJGCF_00640 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
MKBDJGCF_00641 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MKBDJGCF_00642 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKBDJGCF_00643 3.35e-194 ypuA - - S - - - Secreted protein
MKBDJGCF_00644 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKBDJGCF_00645 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
MKBDJGCF_00646 2.37e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MKBDJGCF_00647 7.86e-68 ypuD - - - - - - -
MKBDJGCF_00648 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKBDJGCF_00649 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MKBDJGCF_00650 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKBDJGCF_00651 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKBDJGCF_00652 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKBDJGCF_00653 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MKBDJGCF_00655 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKBDJGCF_00656 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKBDJGCF_00657 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
MKBDJGCF_00658 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKBDJGCF_00659 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MKBDJGCF_00660 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MKBDJGCF_00661 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MKBDJGCF_00662 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MKBDJGCF_00663 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MKBDJGCF_00664 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MKBDJGCF_00665 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_00666 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_00667 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_00668 4.67e-216 rsiX - - - - - - -
MKBDJGCF_00669 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKBDJGCF_00670 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKBDJGCF_00671 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MKBDJGCF_00672 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MKBDJGCF_00673 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MKBDJGCF_00674 2.24e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MKBDJGCF_00675 8.85e-110 ypbE - - M - - - Lysin motif
MKBDJGCF_00676 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
MKBDJGCF_00677 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MKBDJGCF_00678 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKBDJGCF_00679 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MKBDJGCF_00680 1.2e-235 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MKBDJGCF_00681 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MKBDJGCF_00682 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MKBDJGCF_00683 9.02e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
MKBDJGCF_00684 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
MKBDJGCF_00685 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
MKBDJGCF_00686 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MKBDJGCF_00687 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MKBDJGCF_00688 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKBDJGCF_00689 6.38e-129 yphA - - - - - - -
MKBDJGCF_00690 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MKBDJGCF_00691 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MKBDJGCF_00692 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
MKBDJGCF_00693 2.47e-166 yphF - - - - - - -
MKBDJGCF_00695 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKBDJGCF_00696 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKBDJGCF_00697 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MKBDJGCF_00698 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MKBDJGCF_00699 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MKBDJGCF_00700 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKBDJGCF_00701 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MKBDJGCF_00702 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MKBDJGCF_00703 8e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MKBDJGCF_00704 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKBDJGCF_00705 3.8e-252 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKBDJGCF_00706 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MKBDJGCF_00707 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKBDJGCF_00708 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKBDJGCF_00709 1.91e-157 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MKBDJGCF_00710 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MKBDJGCF_00711 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKBDJGCF_00712 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKBDJGCF_00713 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKBDJGCF_00714 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MKBDJGCF_00715 3.79e-290 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKBDJGCF_00716 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
MKBDJGCF_00717 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
MKBDJGCF_00718 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
MKBDJGCF_00719 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MKBDJGCF_00720 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MKBDJGCF_00721 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MKBDJGCF_00722 6.12e-126 ypjA - - S - - - membrane
MKBDJGCF_00723 1.09e-177 ypjB - - S - - - sporulation protein
MKBDJGCF_00724 1.7e-281 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MKBDJGCF_00725 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_00726 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MKBDJGCF_00727 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKBDJGCF_00728 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MKBDJGCF_00729 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MKBDJGCF_00730 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MKBDJGCF_00731 1.53e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKBDJGCF_00732 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKBDJGCF_00733 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MKBDJGCF_00734 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKBDJGCF_00735 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKBDJGCF_00736 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MKBDJGCF_00737 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MKBDJGCF_00738 2.74e-95 ypmB - - S - - - protein conserved in bacteria
MKBDJGCF_00739 1.1e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MKBDJGCF_00740 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MKBDJGCF_00741 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MKBDJGCF_00742 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKBDJGCF_00743 4.6e-113 ypoC - - - - - - -
MKBDJGCF_00744 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MKBDJGCF_00745 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKBDJGCF_00746 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
MKBDJGCF_00751 1.18e-60 yppG - - S - - - YppG-like protein
MKBDJGCF_00752 6.64e-80 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MKBDJGCF_00753 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MKBDJGCF_00754 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MKBDJGCF_00755 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MKBDJGCF_00757 4.53e-39 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MKBDJGCF_00758 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
MKBDJGCF_00759 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKBDJGCF_00760 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MKBDJGCF_00761 2.19e-96 yqgA - - - - - - -
MKBDJGCF_00762 6.91e-31 - - - S - - - YpzG-like protein
MKBDJGCF_00764 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MKBDJGCF_00765 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKBDJGCF_00766 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKBDJGCF_00767 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MKBDJGCF_00768 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
MKBDJGCF_00769 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
MKBDJGCF_00770 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
MKBDJGCF_00771 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MKBDJGCF_00772 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MKBDJGCF_00773 0.0 ypbR - - S - - - Dynamin family
MKBDJGCF_00774 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
MKBDJGCF_00775 5.97e-11 - - - - - - - -
MKBDJGCF_00776 2.07e-204 ypcP - - L - - - 5'3' exonuclease
MKBDJGCF_00778 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MKBDJGCF_00779 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKBDJGCF_00780 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MKBDJGCF_00781 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
MKBDJGCF_00782 2.05e-09 degR - - - - - - -
MKBDJGCF_00783 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MKBDJGCF_00784 1.01e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MKBDJGCF_00785 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKBDJGCF_00787 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MKBDJGCF_00788 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MKBDJGCF_00789 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MKBDJGCF_00790 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MKBDJGCF_00791 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
MKBDJGCF_00792 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MKBDJGCF_00793 1.41e-142 ypjP - - S - - - YpjP-like protein
MKBDJGCF_00794 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKBDJGCF_00795 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKBDJGCF_00796 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKBDJGCF_00797 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MKBDJGCF_00798 1.54e-207 yplP - - K - - - Transcriptional regulator
MKBDJGCF_00799 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKBDJGCF_00800 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
MKBDJGCF_00801 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MKBDJGCF_00802 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MKBDJGCF_00803 2.45e-122 ypmS - - S - - - protein conserved in bacteria
MKBDJGCF_00804 1.42e-88 ypoP - - K - - - transcriptional
MKBDJGCF_00805 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKBDJGCF_00806 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MKBDJGCF_00807 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MKBDJGCF_00808 6.94e-262 yokA - - L - - - Recombinase
MKBDJGCF_00809 6.05e-22 - - - S - - - Regulatory protein YrvL
MKBDJGCF_00811 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
MKBDJGCF_00814 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MKBDJGCF_00815 5.79e-269 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MKBDJGCF_00816 3.73e-214 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MKBDJGCF_00817 9.24e-83 cgeA - - - ko:K06319 - ko00000 -
MKBDJGCF_00818 4.04e-54 cgeC - - - ko:K06321 - ko00000 -
MKBDJGCF_00819 7.04e-288 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MKBDJGCF_00820 7.99e-176 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MKBDJGCF_00822 8.69e-84 - - - L - - - Bacterial transcription activator, effector binding domain
MKBDJGCF_00824 7.19e-298 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKBDJGCF_00825 1.05e-155 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKBDJGCF_00826 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKBDJGCF_00827 6.72e-316 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MKBDJGCF_00828 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MKBDJGCF_00829 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MKBDJGCF_00830 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
MKBDJGCF_00831 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
MKBDJGCF_00832 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_00833 1.18e-155 yodN - - - - - - -
MKBDJGCF_00835 1.97e-33 yozD - - S - - - YozD-like protein
MKBDJGCF_00836 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MKBDJGCF_00837 1.16e-72 yodL - - S - - - YodL-like
MKBDJGCF_00839 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MKBDJGCF_00840 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MKBDJGCF_00841 2.3e-30 yodI - - - - - - -
MKBDJGCF_00842 4.97e-156 yodH - - Q - - - Methyltransferase
MKBDJGCF_00843 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MKBDJGCF_00844 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_00845 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKBDJGCF_00846 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MKBDJGCF_00847 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKBDJGCF_00848 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
MKBDJGCF_00849 1.52e-212 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MKBDJGCF_00850 1.35e-137 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MKBDJGCF_00851 5.26e-136 yodC - - C - - - nitroreductase
MKBDJGCF_00852 1.93e-69 yodB - - K - - - transcriptional
MKBDJGCF_00853 9.37e-83 iolK - - S - - - tautomerase
MKBDJGCF_00855 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MKBDJGCF_00856 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MKBDJGCF_00857 3.66e-31 - - - - - - - -
MKBDJGCF_00858 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MKBDJGCF_00859 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MKBDJGCF_00860 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKBDJGCF_00861 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MKBDJGCF_00863 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKBDJGCF_00864 6.89e-278 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MKBDJGCF_00865 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MKBDJGCF_00866 2.75e-137 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKBDJGCF_00867 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MKBDJGCF_00868 0.0 yojO - - P - - - Von Willebrand factor
MKBDJGCF_00869 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MKBDJGCF_00870 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MKBDJGCF_00871 3.22e-164 - - - S - - - Metallo-beta-lactamase superfamily
MKBDJGCF_00872 3.93e-208 yocS - - S ko:K03453 - ko00000 -transporter
MKBDJGCF_00873 3.13e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKBDJGCF_00874 5.98e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MKBDJGCF_00875 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MKBDJGCF_00876 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MKBDJGCF_00877 4.69e-43 yozC - - - - - - -
MKBDJGCF_00878 5.32e-75 yozO - - S - - - Bacterial PH domain
MKBDJGCF_00879 1.83e-49 yocN - - - - - - -
MKBDJGCF_00880 8.77e-41 yozN - - - - - - -
MKBDJGCF_00881 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MKBDJGCF_00882 1.16e-11 yocN - - - - - - -
MKBDJGCF_00884 7.44e-78 yocK - - T - - - general stress protein
MKBDJGCF_00885 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKBDJGCF_00887 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MKBDJGCF_00888 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
MKBDJGCF_00890 3.83e-231 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MKBDJGCF_00891 2.99e-119 yocC - - - - - - -
MKBDJGCF_00892 2.97e-173 - - - J - - - Protein required for attachment to host cells
MKBDJGCF_00893 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
MKBDJGCF_00894 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKBDJGCF_00895 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MKBDJGCF_00896 4.42e-57 yobW - - - - - - -
MKBDJGCF_00897 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MKBDJGCF_00898 1.44e-110 yobS - - K - - - Transcriptional regulator
MKBDJGCF_00899 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MKBDJGCF_00900 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MKBDJGCF_00903 1.52e-38 - - - - - - - -
MKBDJGCF_00904 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_00906 6.3e-36 yoaF - - - - - - -
MKBDJGCF_00907 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKBDJGCF_00908 2.4e-237 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKBDJGCF_00909 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MKBDJGCF_00910 1.03e-248 yoaB - - EGP - - - the major facilitator superfamily
MKBDJGCF_00911 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
MKBDJGCF_00912 2.84e-123 tnpR - - L - - - resolvase
MKBDJGCF_00913 4.04e-103 - - - - - - - -
MKBDJGCF_00915 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
MKBDJGCF_00916 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKBDJGCF_00917 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MKBDJGCF_00918 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MKBDJGCF_00919 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
MKBDJGCF_00920 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
MKBDJGCF_00921 6.56e-192 - - - S - - - membrane
MKBDJGCF_00922 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
MKBDJGCF_00923 0.0 - - - I - - - PLD-like domain
MKBDJGCF_00924 1.2e-147 yoxB - - - - - - -
MKBDJGCF_00925 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKBDJGCF_00926 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_00927 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MKBDJGCF_00928 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKBDJGCF_00929 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKBDJGCF_00930 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_00931 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MKBDJGCF_00932 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKBDJGCF_00933 3.34e-36 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKBDJGCF_00934 1.03e-279 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKBDJGCF_00935 1.91e-66 - - - K - - - Helix-turn-helix domain
MKBDJGCF_00936 1.17e-240 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
MKBDJGCF_00937 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MKBDJGCF_00938 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
MKBDJGCF_00939 7.69e-123 - - - L - - - Integrase
MKBDJGCF_00941 2.04e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MKBDJGCF_00942 9.25e-306 yoeA - - V - - - MATE efflux family protein
MKBDJGCF_00943 3.16e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MKBDJGCF_00944 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MKBDJGCF_00945 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_00946 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
MKBDJGCF_00947 9.31e-83 yngL - - S - - - Protein of unknown function (DUF1360)
MKBDJGCF_00948 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MKBDJGCF_00949 6.97e-264 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MKBDJGCF_00950 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKBDJGCF_00951 1.6e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MKBDJGCF_00952 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MKBDJGCF_00953 2.16e-208 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MKBDJGCF_00954 2.54e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MKBDJGCF_00955 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKBDJGCF_00956 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
MKBDJGCF_00957 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MKBDJGCF_00958 1.02e-88 yngA - - S - - - membrane
MKBDJGCF_00959 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MKBDJGCF_00960 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MKBDJGCF_00961 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKBDJGCF_00962 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKBDJGCF_00963 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MKBDJGCF_00964 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MKBDJGCF_00965 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKBDJGCF_00966 6.43e-136 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKBDJGCF_00967 1.26e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKBDJGCF_00968 3.84e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MKBDJGCF_00969 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_00970 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_00971 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_00972 0.0 - - - Q ko:K15663,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Non-ribosomal peptide synthetase modules and related proteins
MKBDJGCF_00973 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_00974 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MKBDJGCF_00975 3.32e-302 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MKBDJGCF_00976 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
MKBDJGCF_00977 3.49e-282 - - - T - - - Histidine kinase
MKBDJGCF_00978 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
MKBDJGCF_00979 0.0 yndJ - - S - - - YndJ-like protein
MKBDJGCF_00980 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
MKBDJGCF_00981 1.56e-28 yndG - - S - - - DoxX-like family
MKBDJGCF_00982 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MKBDJGCF_00983 2.04e-60 ynfC - - - - - - -
MKBDJGCF_00984 2.21e-19 - - - - - - - -
MKBDJGCF_00985 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKBDJGCF_00986 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKBDJGCF_00987 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MKBDJGCF_00988 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKBDJGCF_00989 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
MKBDJGCF_00990 5.95e-65 yneQ - - - - - - -
MKBDJGCF_00991 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MKBDJGCF_00992 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MKBDJGCF_00994 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKBDJGCF_00995 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKBDJGCF_00996 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MKBDJGCF_00997 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MKBDJGCF_00998 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
MKBDJGCF_00999 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
MKBDJGCF_01000 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MKBDJGCF_01001 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MKBDJGCF_01002 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MKBDJGCF_01003 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
MKBDJGCF_01004 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MKBDJGCF_01005 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MKBDJGCF_01006 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKBDJGCF_01007 2.33e-43 ynzC - - S - - - UPF0291 protein
MKBDJGCF_01008 4.8e-141 yneB - - L - - - resolvase
MKBDJGCF_01009 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MKBDJGCF_01010 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKBDJGCF_01012 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
MKBDJGCF_01013 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MKBDJGCF_01014 4.12e-10 - - - - - - - -
MKBDJGCF_01015 2.53e-162 yndL - - S - - - Replication protein
MKBDJGCF_01016 3.99e-33 - - - S - - - Domain of unknown function (DUF4177)
MKBDJGCF_01017 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MKBDJGCF_01018 1.33e-43 - - - S - - - TM2 domain
MKBDJGCF_01019 0.0 yobO - - M - - - Pectate lyase superfamily protein
MKBDJGCF_01021 1.97e-119 yvgO - - - - - - -
MKBDJGCF_01022 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MKBDJGCF_01023 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
MKBDJGCF_01024 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_01025 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
MKBDJGCF_01027 1.87e-53 - - - - - - - -
MKBDJGCF_01029 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
MKBDJGCF_01030 1.52e-164 yoaP - - K - - - YoaP-like
MKBDJGCF_01031 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MKBDJGCF_01032 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
MKBDJGCF_01033 2.04e-10 - - - - - - - -
MKBDJGCF_01034 5.82e-16 - - - - - - - -
MKBDJGCF_01035 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MKBDJGCF_01036 1.08e-86 dinB - - S - - - DinB family
MKBDJGCF_01038 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MKBDJGCF_01039 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MKBDJGCF_01041 3.77e-225 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MKBDJGCF_01042 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
MKBDJGCF_01043 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MKBDJGCF_01044 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MKBDJGCF_01045 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MKBDJGCF_01046 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MKBDJGCF_01047 6.16e-263 xylR - - GK - - - ROK family
MKBDJGCF_01048 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MKBDJGCF_01049 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MKBDJGCF_01050 2.55e-270 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MKBDJGCF_01051 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MKBDJGCF_01054 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MKBDJGCF_01055 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MKBDJGCF_01056 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MKBDJGCF_01057 5.57e-288 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKBDJGCF_01058 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MKBDJGCF_01059 2e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_01060 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_01061 2.21e-132 ymaB - - S - - - MutT family
MKBDJGCF_01062 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKBDJGCF_01063 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKBDJGCF_01064 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MKBDJGCF_01065 2.31e-29 ymzA - - - - - - -
MKBDJGCF_01066 1.87e-53 - - - - - - - -
MKBDJGCF_01067 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MKBDJGCF_01068 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKBDJGCF_01069 1.06e-70 ymaF - - S - - - YmaF family
MKBDJGCF_01071 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MKBDJGCF_01072 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MKBDJGCF_01073 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MKBDJGCF_01074 3.08e-151 ymaC - - S - - - Replication protein
MKBDJGCF_01075 2.64e-07 - - - - - - - -
MKBDJGCF_01076 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MKBDJGCF_01077 9.32e-81 ymzB - - - - - - -
MKBDJGCF_01078 3.52e-149 yoaK - - S - - - Membrane
MKBDJGCF_01079 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
MKBDJGCF_01080 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MKBDJGCF_01081 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MKBDJGCF_01082 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MKBDJGCF_01083 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MKBDJGCF_01084 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MKBDJGCF_01085 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MKBDJGCF_01086 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MKBDJGCF_01087 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MKBDJGCF_01088 9.98e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MKBDJGCF_01089 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MKBDJGCF_01090 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MKBDJGCF_01091 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MKBDJGCF_01092 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MKBDJGCF_01093 3.58e-160 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MKBDJGCF_01094 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKBDJGCF_01095 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKBDJGCF_01096 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
MKBDJGCF_01097 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MKBDJGCF_01098 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKBDJGCF_01099 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKBDJGCF_01100 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MKBDJGCF_01101 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MKBDJGCF_01102 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MKBDJGCF_01103 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MKBDJGCF_01104 4.31e-260 pbpX - - V - - - Beta-lactamase
MKBDJGCF_01105 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKBDJGCF_01106 2.57e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MKBDJGCF_01107 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKBDJGCF_01108 2.26e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MKBDJGCF_01109 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
MKBDJGCF_01110 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
MKBDJGCF_01111 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MKBDJGCF_01112 2.09e-303 ymfH - - S - - - zinc protease
MKBDJGCF_01113 8.12e-300 albE - - S - - - Peptidase M16
MKBDJGCF_01114 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MKBDJGCF_01115 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_01116 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_01117 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_01118 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MKBDJGCF_01119 7.4e-41 - - - S - - - YlzJ-like protein
MKBDJGCF_01120 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MKBDJGCF_01121 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKBDJGCF_01122 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKBDJGCF_01123 1.83e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MKBDJGCF_01124 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKBDJGCF_01125 6.97e-131 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MKBDJGCF_01126 4.32e-202 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MKBDJGCF_01127 2.17e-56 ymxH - - S - - - YlmC YmxH family
MKBDJGCF_01128 9.79e-298 mlpA - - S - - - Belongs to the peptidase M16 family
MKBDJGCF_01129 2.3e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MKBDJGCF_01130 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKBDJGCF_01131 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKBDJGCF_01132 1.27e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MKBDJGCF_01133 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKBDJGCF_01134 2.38e-67 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKBDJGCF_01135 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MKBDJGCF_01136 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKBDJGCF_01137 6.16e-63 ylxQ - - J - - - ribosomal protein
MKBDJGCF_01138 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MKBDJGCF_01139 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MKBDJGCF_01140 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MKBDJGCF_01141 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKBDJGCF_01142 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKBDJGCF_01143 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MKBDJGCF_01144 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKBDJGCF_01145 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MKBDJGCF_01146 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKBDJGCF_01147 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKBDJGCF_01148 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MKBDJGCF_01149 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKBDJGCF_01150 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MKBDJGCF_01151 2.54e-84 ylxL - - - - - - -
MKBDJGCF_01152 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_01153 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MKBDJGCF_01154 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MKBDJGCF_01155 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MKBDJGCF_01156 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MKBDJGCF_01157 1.2e-240 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MKBDJGCF_01158 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MKBDJGCF_01159 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MKBDJGCF_01160 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKBDJGCF_01161 3.29e-238 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKBDJGCF_01162 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MKBDJGCF_01163 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MKBDJGCF_01164 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MKBDJGCF_01165 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MKBDJGCF_01166 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MKBDJGCF_01167 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKBDJGCF_01168 7.38e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKBDJGCF_01169 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MKBDJGCF_01170 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MKBDJGCF_01171 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MKBDJGCF_01172 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MKBDJGCF_01173 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
MKBDJGCF_01174 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MKBDJGCF_01175 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MKBDJGCF_01176 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MKBDJGCF_01177 3.52e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKBDJGCF_01178 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MKBDJGCF_01179 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MKBDJGCF_01180 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MKBDJGCF_01181 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MKBDJGCF_01182 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKBDJGCF_01183 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKBDJGCF_01184 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKBDJGCF_01185 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MKBDJGCF_01186 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKBDJGCF_01187 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKBDJGCF_01188 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MKBDJGCF_01189 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKBDJGCF_01190 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKBDJGCF_01191 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MKBDJGCF_01192 0.0 ylqG - - - - - - -
MKBDJGCF_01193 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKBDJGCF_01194 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKBDJGCF_01195 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKBDJGCF_01196 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MKBDJGCF_01197 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKBDJGCF_01198 5.66e-79 ylqD - - S - - - YlqD protein
MKBDJGCF_01199 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MKBDJGCF_01200 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MKBDJGCF_01201 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKBDJGCF_01202 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKBDJGCF_01203 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKBDJGCF_01204 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MKBDJGCF_01205 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKBDJGCF_01206 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKBDJGCF_01207 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MKBDJGCF_01208 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MKBDJGCF_01209 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKBDJGCF_01210 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MKBDJGCF_01211 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKBDJGCF_01212 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MKBDJGCF_01213 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MKBDJGCF_01214 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MKBDJGCF_01215 6.07e-77 yloU - - S - - - protein conserved in bacteria
MKBDJGCF_01216 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MKBDJGCF_01217 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MKBDJGCF_01218 1.69e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MKBDJGCF_01219 2.43e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKBDJGCF_01220 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MKBDJGCF_01221 2.84e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MKBDJGCF_01222 3.58e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKBDJGCF_01223 6.91e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKBDJGCF_01224 6.66e-215 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKBDJGCF_01225 1.61e-107 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKBDJGCF_01226 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKBDJGCF_01227 2.84e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKBDJGCF_01228 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKBDJGCF_01229 1.64e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MKBDJGCF_01230 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MKBDJGCF_01231 3.26e-193 yloC - - S - - - stress-induced protein
MKBDJGCF_01232 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MKBDJGCF_01233 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MKBDJGCF_01234 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MKBDJGCF_01235 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MKBDJGCF_01236 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MKBDJGCF_01237 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MKBDJGCF_01238 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MKBDJGCF_01239 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MKBDJGCF_01240 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MKBDJGCF_01241 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MKBDJGCF_01242 3.5e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKBDJGCF_01243 2.37e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKBDJGCF_01244 1.17e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKBDJGCF_01245 2.68e-176 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MKBDJGCF_01246 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MKBDJGCF_01247 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MKBDJGCF_01248 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKBDJGCF_01249 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MKBDJGCF_01250 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MKBDJGCF_01251 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKBDJGCF_01252 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MKBDJGCF_01253 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKBDJGCF_01254 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
MKBDJGCF_01255 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKBDJGCF_01256 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MKBDJGCF_01257 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
MKBDJGCF_01258 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MKBDJGCF_01259 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKBDJGCF_01260 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKBDJGCF_01261 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MKBDJGCF_01262 7.13e-52 ylmC - - S - - - sporulation protein
MKBDJGCF_01263 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MKBDJGCF_01264 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MKBDJGCF_01265 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_01266 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_01267 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MKBDJGCF_01268 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MKBDJGCF_01269 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKBDJGCF_01270 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKBDJGCF_01271 1.07e-169 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKBDJGCF_01272 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MKBDJGCF_01273 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKBDJGCF_01274 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MKBDJGCF_01275 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKBDJGCF_01276 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKBDJGCF_01277 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKBDJGCF_01278 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MKBDJGCF_01279 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MKBDJGCF_01280 2.81e-67 ftsL - - D - - - Essential cell division protein
MKBDJGCF_01281 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKBDJGCF_01282 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MKBDJGCF_01283 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKBDJGCF_01284 4.86e-194 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKBDJGCF_01285 2.68e-115 ylbP - - K - - - n-acetyltransferase
MKBDJGCF_01286 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MKBDJGCF_01287 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MKBDJGCF_01288 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MKBDJGCF_01289 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
MKBDJGCF_01290 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MKBDJGCF_01291 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MKBDJGCF_01292 5.75e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MKBDJGCF_01293 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKBDJGCF_01294 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MKBDJGCF_01295 4.62e-56 ylbG - - S - - - UPF0298 protein
MKBDJGCF_01296 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
MKBDJGCF_01297 1.73e-48 ylbE - - S - - - YlbE-like protein
MKBDJGCF_01298 5.5e-83 ylbD - - S - - - Putative coat protein
MKBDJGCF_01299 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
MKBDJGCF_01300 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
MKBDJGCF_01301 8.01e-77 ylbA - - S - - - YugN-like family
MKBDJGCF_01302 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MKBDJGCF_01303 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MKBDJGCF_01304 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MKBDJGCF_01305 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKBDJGCF_01306 2.78e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MKBDJGCF_01307 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKBDJGCF_01308 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MKBDJGCF_01309 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKBDJGCF_01310 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MKBDJGCF_01311 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
MKBDJGCF_01312 1.94e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MKBDJGCF_01313 7.69e-105 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKBDJGCF_01314 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MKBDJGCF_01315 1.88e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKBDJGCF_01316 7.95e-45 ylaI - - S - - - protein conserved in bacteria
MKBDJGCF_01317 1.41e-64 - - - S - - - YlaH-like protein
MKBDJGCF_01318 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MKBDJGCF_01319 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
MKBDJGCF_01320 1.62e-56 ylaE - - - - - - -
MKBDJGCF_01322 9.3e-32 ylaA - - - - - - -
MKBDJGCF_01323 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MKBDJGCF_01324 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
MKBDJGCF_01325 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MKBDJGCF_01326 7.89e-32 ykzI - - - - - - -
MKBDJGCF_01327 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
MKBDJGCF_01328 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
MKBDJGCF_01329 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MKBDJGCF_01330 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MKBDJGCF_01331 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MKBDJGCF_01332 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKBDJGCF_01333 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKBDJGCF_01334 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKBDJGCF_01335 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKBDJGCF_01336 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
MKBDJGCF_01337 1.04e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MKBDJGCF_01338 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKBDJGCF_01339 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
MKBDJGCF_01340 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
MKBDJGCF_01341 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKBDJGCF_01342 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKBDJGCF_01343 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MKBDJGCF_01344 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MKBDJGCF_01345 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MKBDJGCF_01346 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MKBDJGCF_01347 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MKBDJGCF_01348 7.7e-19 - - - S - - - Uncharacterized protein YkpC
MKBDJGCF_01349 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MKBDJGCF_01350 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKBDJGCF_01351 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKBDJGCF_01352 3.54e-48 ykoA - - - - - - -
MKBDJGCF_01353 4.41e-137 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MKBDJGCF_01354 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKBDJGCF_01355 6.86e-51 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKBDJGCF_01356 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MKBDJGCF_01357 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_01358 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MKBDJGCF_01359 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01360 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKBDJGCF_01361 1.65e-133 yknW - - S - - - Yip1 domain
MKBDJGCF_01362 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKBDJGCF_01363 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MKBDJGCF_01364 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MKBDJGCF_01365 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MKBDJGCF_01366 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKBDJGCF_01367 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MKBDJGCF_01368 8.39e-201 yknT - - - ko:K06437 - ko00000 -
MKBDJGCF_01369 3.55e-125 rok - - K - - - Repressor of ComK
MKBDJGCF_01371 1.9e-93 ykuV - - CO - - - thiol-disulfide
MKBDJGCF_01373 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MKBDJGCF_01374 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
MKBDJGCF_01375 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKBDJGCF_01376 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKBDJGCF_01377 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
MKBDJGCF_01378 1.07e-207 ykuO - - - - - - -
MKBDJGCF_01379 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
MKBDJGCF_01380 1.08e-214 ccpC - - K - - - Transcriptional regulator
MKBDJGCF_01381 8.55e-99 ykuL - - S - - - CBS domain
MKBDJGCF_01382 2.63e-36 ykzF - - S - - - Antirepressor AbbA
MKBDJGCF_01383 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
MKBDJGCF_01384 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
MKBDJGCF_01385 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
MKBDJGCF_01387 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_01388 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MKBDJGCF_01389 3.48e-114 ykuD - - S - - - protein conserved in bacteria
MKBDJGCF_01390 8.16e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_01391 1.45e-107 ykyB - - S - - - YkyB-like protein
MKBDJGCF_01392 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MKBDJGCF_01393 2.22e-15 - - - - - - - -
MKBDJGCF_01394 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MKBDJGCF_01395 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_01396 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MKBDJGCF_01397 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
MKBDJGCF_01398 9.19e-65 - - - - - - - -
MKBDJGCF_01399 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKBDJGCF_01400 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MKBDJGCF_01401 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MKBDJGCF_01402 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_01403 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKBDJGCF_01404 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MKBDJGCF_01405 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_01406 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MKBDJGCF_01407 4.21e-217 ykvZ - - K - - - Transcriptional regulator
MKBDJGCF_01409 1.51e-259 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MKBDJGCF_01410 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MKBDJGCF_01411 4.22e-105 stoA - - CO - - - thiol-disulfide
MKBDJGCF_01412 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_01413 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MKBDJGCF_01414 8.76e-38 - - - - - - - -
MKBDJGCF_01415 1.56e-34 ykvS - - S - - - protein conserved in bacteria
MKBDJGCF_01416 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
MKBDJGCF_01417 2.11e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKBDJGCF_01418 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MKBDJGCF_01419 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MKBDJGCF_01420 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKBDJGCF_01421 1.81e-196 - - - - - - - -
MKBDJGCF_01423 6.18e-222 ykvI - - S - - - membrane
MKBDJGCF_01424 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MKBDJGCF_01425 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MKBDJGCF_01426 2.49e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MKBDJGCF_01427 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MKBDJGCF_01428 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MKBDJGCF_01430 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MKBDJGCF_01431 1.15e-140 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MKBDJGCF_01432 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MKBDJGCF_01433 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MKBDJGCF_01434 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MKBDJGCF_01435 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKBDJGCF_01436 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MKBDJGCF_01437 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MKBDJGCF_01439 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKBDJGCF_01440 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_01441 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MKBDJGCF_01442 1.37e-26 ykzE - - - - - - -
MKBDJGCF_01443 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
MKBDJGCF_01444 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MKBDJGCF_01445 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MKBDJGCF_01446 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
MKBDJGCF_01447 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MKBDJGCF_01448 3.51e-221 ykrI - - S - - - Anti-sigma factor N-terminus
MKBDJGCF_01449 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_01450 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKBDJGCF_01451 1.21e-123 ykoX - - S - - - membrane-associated protein
MKBDJGCF_01452 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MKBDJGCF_01453 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKBDJGCF_01454 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MKBDJGCF_01455 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
MKBDJGCF_01456 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MKBDJGCF_01457 3.57e-35 ykoL - - - - - - -
MKBDJGCF_01458 2.24e-23 - - - - - - - -
MKBDJGCF_01459 3.53e-69 tnrA - - K - - - transcriptional
MKBDJGCF_01460 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MKBDJGCF_01462 5.3e-302 ydhD - - M - - - Glycosyl hydrolase
MKBDJGCF_01463 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MKBDJGCF_01464 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01465 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MKBDJGCF_01466 8.47e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKBDJGCF_01467 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKBDJGCF_01468 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKBDJGCF_01469 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MKBDJGCF_01470 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_01471 8.96e-151 - - - K - - - Collagen triple helix repeat
MKBDJGCF_01472 2.15e-260 - - - M - - - Glycosyl transferase family 2
MKBDJGCF_01474 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MKBDJGCF_01475 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
MKBDJGCF_01476 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
MKBDJGCF_01477 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
MKBDJGCF_01478 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKBDJGCF_01479 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKBDJGCF_01480 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MKBDJGCF_01481 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MKBDJGCF_01482 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MKBDJGCF_01483 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKBDJGCF_01484 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
MKBDJGCF_01485 1.45e-179 ykgA - - E - - - Amidinotransferase
MKBDJGCF_01486 6.11e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MKBDJGCF_01487 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_01488 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKBDJGCF_01489 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MKBDJGCF_01490 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MKBDJGCF_01491 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MKBDJGCF_01492 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_01493 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_01494 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_01495 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MKBDJGCF_01496 0.0 yubD - - P - - - Major Facilitator Superfamily
MKBDJGCF_01497 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKBDJGCF_01499 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_01500 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKBDJGCF_01501 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MKBDJGCF_01502 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
MKBDJGCF_01503 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MKBDJGCF_01504 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
MKBDJGCF_01505 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MKBDJGCF_01506 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MKBDJGCF_01507 4.2e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_01508 5.3e-49 xhlB - - S - - - SPP1 phage holin
MKBDJGCF_01509 6.44e-50 xhlA - - S - - - Haemolysin XhlA
MKBDJGCF_01510 2.64e-134 xepA - - - - - - -
MKBDJGCF_01511 2.74e-23 xkdX - - - - - - -
MKBDJGCF_01512 6.09e-58 xkdW - - S - - - XkdW protein
MKBDJGCF_01513 2.06e-224 - - - - - - - -
MKBDJGCF_01514 1.48e-36 - - - - - - - -
MKBDJGCF_01515 2.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MKBDJGCF_01516 5.1e-211 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKBDJGCF_01517 1.65e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
MKBDJGCF_01518 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
MKBDJGCF_01519 2.78e-208 xkdQ - - G - - - NLP P60 protein
MKBDJGCF_01520 1.88e-144 xkdP - - S - - - Lysin motif
MKBDJGCF_01521 4.3e-253 xkdO - - L - - - Transglycosylase SLT domain
MKBDJGCF_01522 2.1e-270 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MKBDJGCF_01523 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKBDJGCF_01524 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
MKBDJGCF_01525 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MKBDJGCF_01526 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MKBDJGCF_01527 1.35e-216 ybaS - - S - - - Na -dependent transporter
MKBDJGCF_01528 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
MKBDJGCF_01529 8.14e-222 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_01530 5.16e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_01531 3.89e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MKBDJGCF_01532 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MKBDJGCF_01533 4.44e-291 ybbC - - S - - - protein conserved in bacteria
MKBDJGCF_01534 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MKBDJGCF_01535 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MKBDJGCF_01536 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_01537 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKBDJGCF_01538 1.33e-105 ybbJ - - J - - - acetyltransferase
MKBDJGCF_01539 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
MKBDJGCF_01545 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_01546 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MKBDJGCF_01547 7.39e-187 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKBDJGCF_01548 1.1e-291 ybbR - - S - - - protein conserved in bacteria
MKBDJGCF_01549 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKBDJGCF_01550 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKBDJGCF_01551 2.66e-27 - - - S - - - peptidyl-tyrosine sulfation
MKBDJGCF_01552 6.65e-56 - - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 ATPase activity
MKBDJGCF_01553 1.49e-144 - - - O - - - growth
MKBDJGCF_01554 5.91e-68 - - - S - - - ABC-2 family transporter protein
MKBDJGCF_01555 5.33e-125 ybdN - - - - - - -
MKBDJGCF_01556 8.77e-168 ybdO - - S - - - Domain of unknown function (DUF4885)
MKBDJGCF_01557 5.5e-202 dkgB - - S - - - Aldo/keto reductase family
MKBDJGCF_01558 3.49e-134 yxaC - - M - - - effector of murein hydrolase
MKBDJGCF_01559 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MKBDJGCF_01560 6.3e-90 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_01561 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_01562 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MKBDJGCF_01563 6.05e-227 - - - T - - - COG4585 Signal transduction histidine kinase
MKBDJGCF_01564 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MKBDJGCF_01565 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MKBDJGCF_01566 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MKBDJGCF_01567 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MKBDJGCF_01568 6.5e-33 - - - - - - - -
MKBDJGCF_01569 3.66e-103 - - - S - - - Domain of unknown function (DUF4879)
MKBDJGCF_01570 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MKBDJGCF_01571 1.42e-134 yqeB - - - - - - -
MKBDJGCF_01572 2.17e-52 ybyB - - - - - - -
MKBDJGCF_01573 0.0 ybeC - - E - - - amino acid
MKBDJGCF_01574 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
MKBDJGCF_01575 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MKBDJGCF_01576 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MKBDJGCF_01577 1e-23 - - - S - - - Protein of unknown function (DUF2651)
MKBDJGCF_01578 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MKBDJGCF_01580 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_01581 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MKBDJGCF_01582 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKBDJGCF_01583 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKBDJGCF_01584 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
MKBDJGCF_01585 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MKBDJGCF_01586 9.76e-52 ybfN - - - - - - -
MKBDJGCF_01587 4.36e-240 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MKBDJGCF_01588 2.61e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKBDJGCF_01589 5.77e-246 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MKBDJGCF_01590 3.37e-301 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MKBDJGCF_01591 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MKBDJGCF_01592 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MKBDJGCF_01593 1.1e-195 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MKBDJGCF_01594 2.32e-262 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_01595 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MKBDJGCF_01596 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MKBDJGCF_01597 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MKBDJGCF_01598 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKBDJGCF_01599 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MKBDJGCF_01600 1.8e-172 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MKBDJGCF_01601 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
MKBDJGCF_01602 3.11e-73 ydfQ - - CO - - - Thioredoxin
MKBDJGCF_01603 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
MKBDJGCF_01604 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MKBDJGCF_01605 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MKBDJGCF_01606 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKBDJGCF_01607 1.44e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKBDJGCF_01608 1.63e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKBDJGCF_01609 1.19e-241 ycbU - - E - - - Selenocysteine lyase
MKBDJGCF_01610 1.26e-306 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MKBDJGCF_01611 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MKBDJGCF_01612 1.19e-58 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKBDJGCF_01613 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKBDJGCF_01614 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
MKBDJGCF_01615 6.43e-211 yccK - - C - - - Aldo keto reductase
MKBDJGCF_01616 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
MKBDJGCF_01617 2.82e-300 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_01618 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_01619 5.55e-116 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MKBDJGCF_01620 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MKBDJGCF_01621 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MKBDJGCF_01622 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MKBDJGCF_01623 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
MKBDJGCF_01624 1.86e-62 - - - K - - - Virulence activator alpha C-term
MKBDJGCF_01625 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MKBDJGCF_01626 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKBDJGCF_01627 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKBDJGCF_01628 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_01629 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MKBDJGCF_01630 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MKBDJGCF_01631 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MKBDJGCF_01632 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MKBDJGCF_01633 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MKBDJGCF_01634 1.36e-245 yceH - - P - - - Belongs to the TelA family
MKBDJGCF_01635 1.71e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MKBDJGCF_01637 7.07e-290 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MKBDJGCF_01638 3.48e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MKBDJGCF_01639 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MKBDJGCF_01640 3.87e-262 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MKBDJGCF_01641 8.16e-287 ycgA - - S - - - Membrane
MKBDJGCF_01642 1.04e-53 ycgB - - - - - - -
MKBDJGCF_01643 1.05e-15 - - - S - - - RDD family
MKBDJGCF_01644 1.28e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MKBDJGCF_01645 0.0 mdr - - EGP - - - the major facilitator superfamily
MKBDJGCF_01646 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_01647 2.38e-130 ycgF - - E - - - Lysine exporter protein LysE YggA
MKBDJGCF_01648 3.42e-66 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MKBDJGCF_01649 3.71e-103 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MKBDJGCF_01650 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_01651 5.63e-30 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MKBDJGCF_01652 7.68e-97 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MKBDJGCF_01653 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKBDJGCF_01654 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MKBDJGCF_01655 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_01656 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKBDJGCF_01657 7.44e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MKBDJGCF_01658 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MKBDJGCF_01659 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MKBDJGCF_01660 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKBDJGCF_01661 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKBDJGCF_01662 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MKBDJGCF_01663 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MKBDJGCF_01664 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MKBDJGCF_01665 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MKBDJGCF_01666 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKBDJGCF_01667 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MKBDJGCF_01668 9.85e-281 yciC - - S - - - GTPases (G3E family)
MKBDJGCF_01669 2.62e-278 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKBDJGCF_01670 3.65e-94 yckC - - S - - - membrane
MKBDJGCF_01671 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
MKBDJGCF_01672 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKBDJGCF_01673 7.34e-86 nin - - S - - - Competence protein J (ComJ)
MKBDJGCF_01674 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
MKBDJGCF_01675 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MKBDJGCF_01676 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MKBDJGCF_01677 2.89e-84 hxlR - - K - - - transcriptional
MKBDJGCF_01682 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKBDJGCF_01683 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MKBDJGCF_01684 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MKBDJGCF_01685 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
MKBDJGCF_01686 0.0 ybeC - - E - - - amino acid
MKBDJGCF_01687 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
MKBDJGCF_01688 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MKBDJGCF_01689 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MKBDJGCF_01690 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MKBDJGCF_01691 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
MKBDJGCF_01692 1.56e-166 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MKBDJGCF_01693 2.49e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MKBDJGCF_01694 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
MKBDJGCF_01696 3.98e-311 pbpE - - V - - - Beta-lactamase
MKBDJGCF_01698 2.91e-276 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKBDJGCF_01699 1.47e-144 ydhC - - K - - - FCD
MKBDJGCF_01700 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MKBDJGCF_01701 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
MKBDJGCF_01702 1.15e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MKBDJGCF_01703 1.49e-147 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKBDJGCF_01704 8.31e-21 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKBDJGCF_01705 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
MKBDJGCF_01706 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MKBDJGCF_01707 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MKBDJGCF_01708 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_01709 5.7e-281 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKBDJGCF_01710 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MKBDJGCF_01711 1.89e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MKBDJGCF_01712 1.67e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_01713 4.32e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
MKBDJGCF_01714 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MKBDJGCF_01715 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MKBDJGCF_01716 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MKBDJGCF_01717 4.73e-47 yraG - - - ko:K06440 - ko00000 -
MKBDJGCF_01718 4.76e-84 yraF - - M - - - Spore coat protein
MKBDJGCF_01719 3.98e-278 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKBDJGCF_01720 4.86e-33 yraE - - - ko:K06440 - ko00000 -
MKBDJGCF_01721 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
MKBDJGCF_01722 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_01723 2.99e-192 ydeK - - EG - - - -transporter
MKBDJGCF_01724 1.23e-128 ydeS - - K - - - Transcriptional regulator
MKBDJGCF_01725 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MKBDJGCF_01726 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_01727 1.34e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MKBDJGCF_01728 6.33e-278 nhaC_1 - - C - - - antiporter
MKBDJGCF_01729 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MKBDJGCF_01730 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MKBDJGCF_01731 3.65e-206 - - - S - - - Sodium Bile acid symporter family
MKBDJGCF_01732 7.14e-63 ydeH - - - - - - -
MKBDJGCF_01733 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MKBDJGCF_01735 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MKBDJGCF_01736 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MKBDJGCF_01737 1.19e-124 yrkC - - G - - - Cupin domain
MKBDJGCF_01738 3.58e-201 - - - S - - - SNARE associated Golgi protein
MKBDJGCF_01739 7.27e-197 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MKBDJGCF_01740 6.38e-91 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_01741 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MKBDJGCF_01743 4.07e-219 - - - S - - - Patatin-like phospholipase
MKBDJGCF_01744 4.84e-239 ydeG - - EGP - - - Major facilitator superfamily
MKBDJGCF_01745 8.09e-300 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_01746 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
MKBDJGCF_01747 1e-131 - - - S - - - Protein of unknown function (DUF2812)
MKBDJGCF_01748 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MKBDJGCF_01749 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MKBDJGCF_01750 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKBDJGCF_01751 1.19e-99 - - - K - - - Transcriptional regulator
MKBDJGCF_01752 3.96e-71 - - - - - - - -
MKBDJGCF_01754 7.77e-65 ohrR - - K - - - Transcriptional regulator
MKBDJGCF_01755 3.54e-62 ohrB - - O - - - OsmC-like protein
MKBDJGCF_01756 1.06e-176 - - - I ko:K01066 - ko00000,ko01000 esterase
MKBDJGCF_01764 4.1e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MKBDJGCF_01765 1.78e-21 - - - - - - - -
MKBDJGCF_01766 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MKBDJGCF_01767 2.16e-136 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MKBDJGCF_01768 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKBDJGCF_01769 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MKBDJGCF_01770 3.28e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MKBDJGCF_01771 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MKBDJGCF_01772 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MKBDJGCF_01773 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MKBDJGCF_01774 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MKBDJGCF_01775 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MKBDJGCF_01776 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MKBDJGCF_01777 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKBDJGCF_01778 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MKBDJGCF_01779 4.96e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKBDJGCF_01780 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MKBDJGCF_01781 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MKBDJGCF_01782 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MKBDJGCF_01783 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKBDJGCF_01784 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKBDJGCF_01785 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MKBDJGCF_01786 2.25e-74 ydbP - - CO - - - Thioredoxin
MKBDJGCF_01787 9.92e-161 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKBDJGCF_01788 6.11e-15 - - - S - - - Fur-regulated basic protein A
MKBDJGCF_01789 2.36e-17 - - - S - - - Fur-regulated basic protein B
MKBDJGCF_01790 3.34e-143 ydbM - - I - - - acyl-CoA dehydrogenase
MKBDJGCF_01791 8.26e-89 ydbM - - I - - - acyl-CoA dehydrogenase
MKBDJGCF_01792 1.32e-69 ydbL - - - - - - -
MKBDJGCF_01793 9.52e-165 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKBDJGCF_01794 7e-214 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01795 1.31e-225 ydbI - - S - - - AI-2E family transporter
MKBDJGCF_01796 3.75e-285 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKBDJGCF_01797 4.6e-147 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MKBDJGCF_01798 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MKBDJGCF_01799 7.93e-248 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKBDJGCF_01800 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
MKBDJGCF_01801 1.14e-76 ydbC - - S - - - Domain of unknown function (DUF4937
MKBDJGCF_01802 3.48e-74 ydbB - - G - - - Cupin domain
MKBDJGCF_01803 3.49e-172 ydbA - - P - - - EcsC protein family
MKBDJGCF_01804 2.18e-68 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MKBDJGCF_01805 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MKBDJGCF_01806 3.94e-45 ydaT - - - - - - -
MKBDJGCF_01808 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MKBDJGCF_01809 1.06e-53 - - - - - - - -
MKBDJGCF_01812 1.77e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MKBDJGCF_01813 1.04e-83 - - - - - - - -
MKBDJGCF_01814 7.58e-111 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKBDJGCF_01815 5.03e-80 - - - K - - - acetyltransferase
MKBDJGCF_01816 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MKBDJGCF_01817 0.0 ydaO - - E - - - amino acid
MKBDJGCF_01818 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MKBDJGCF_01819 8.42e-299 ydaM - - M - - - Glycosyl transferase family group 2
MKBDJGCF_01820 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MKBDJGCF_01821 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MKBDJGCF_01822 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKBDJGCF_01823 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKBDJGCF_01824 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MKBDJGCF_01825 7.65e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MKBDJGCF_01826 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MKBDJGCF_01827 4.32e-100 ydaG - - S - - - general stress protein
MKBDJGCF_01828 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKBDJGCF_01829 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MKBDJGCF_01830 6.33e-182 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_01831 0.0 ydaB - - IQ - - - acyl-CoA ligase
MKBDJGCF_01832 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MKBDJGCF_01833 7.28e-212 ycsN - - S - - - Oxidoreductase
MKBDJGCF_01834 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MKBDJGCF_01835 6.7e-72 yczJ - - S - - - biosynthesis
MKBDJGCF_01837 9.77e-144 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MKBDJGCF_01838 7.07e-162 kipR - - K - - - Transcriptional regulator
MKBDJGCF_01839 5.16e-226 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MKBDJGCF_01840 1.68e-168 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MKBDJGCF_01841 3.25e-181 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MKBDJGCF_01842 6.98e-267 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MKBDJGCF_01843 1.42e-170 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MKBDJGCF_01844 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MKBDJGCF_01846 5.81e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MKBDJGCF_01847 8.36e-257 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MKBDJGCF_01848 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MKBDJGCF_01849 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MKBDJGCF_01850 6.5e-71 - - - - - - - -
MKBDJGCF_01851 3.23e-133 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MKBDJGCF_01852 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MKBDJGCF_01853 6.58e-128 ycnI - - S - - - protein conserved in bacteria
MKBDJGCF_01854 3.14e-182 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_01855 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MKBDJGCF_01856 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKBDJGCF_01857 3.02e-278 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKBDJGCF_01858 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_01859 1.08e-67 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MKBDJGCF_01860 2.79e-59 ycnE - - S - - - Monooxygenase
MKBDJGCF_01861 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
MKBDJGCF_01862 4.78e-192 ycnC - - K - - - Transcriptional regulator
MKBDJGCF_01863 1.98e-313 ycnB - - EGP - - - the major facilitator superfamily
MKBDJGCF_01864 1.95e-219 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MKBDJGCF_01865 2.01e-44 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01887 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MKBDJGCF_01888 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
MKBDJGCF_01889 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MKBDJGCF_01890 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MKBDJGCF_01891 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MKBDJGCF_01892 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKBDJGCF_01893 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MKBDJGCF_01894 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MKBDJGCF_01895 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MKBDJGCF_01896 9.63e-230 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MKBDJGCF_01897 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MKBDJGCF_01898 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MKBDJGCF_01899 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MKBDJGCF_01900 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MKBDJGCF_01901 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKBDJGCF_01902 9.99e-98 ytkA - - S - - - YtkA-like
MKBDJGCF_01904 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MKBDJGCF_01905 1.67e-77 ytkC - - S - - - Bacteriophage holin family
MKBDJGCF_01906 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MKBDJGCF_01907 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKBDJGCF_01908 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKBDJGCF_01909 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKBDJGCF_01910 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MKBDJGCF_01911 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
MKBDJGCF_01912 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKBDJGCF_01913 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKBDJGCF_01914 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MKBDJGCF_01915 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_01916 7.46e-80 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKBDJGCF_01917 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MKBDJGCF_01918 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MKBDJGCF_01920 4.07e-133 ytqB - - J - - - Putative rRNA methylase
MKBDJGCF_01921 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MKBDJGCF_01922 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
MKBDJGCF_01924 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MKBDJGCF_01925 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01926 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MKBDJGCF_01927 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MKBDJGCF_01928 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MKBDJGCF_01929 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01930 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MKBDJGCF_01931 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_01932 4.31e-206 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MKBDJGCF_01933 6.3e-170 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_01934 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MKBDJGCF_01935 1.46e-151 ywaF - - S - - - Integral membrane protein
MKBDJGCF_01936 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
MKBDJGCF_01937 1.79e-172 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MKBDJGCF_01938 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
MKBDJGCF_01939 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MKBDJGCF_01940 8.6e-69 ytwF - - P - - - Sulfurtransferase
MKBDJGCF_01941 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
MKBDJGCF_01942 2.49e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MKBDJGCF_01943 1.37e-182 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MKBDJGCF_01944 6.99e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKBDJGCF_01945 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MKBDJGCF_01946 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_01947 3.57e-35 yteV - - S - - - Sporulation protein Cse60
MKBDJGCF_01948 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MKBDJGCF_01949 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MKBDJGCF_01950 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_01951 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MKBDJGCF_01952 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MKBDJGCF_01953 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MKBDJGCF_01954 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MKBDJGCF_01955 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MKBDJGCF_01956 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MKBDJGCF_01957 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MKBDJGCF_01958 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKBDJGCF_01959 2.86e-198 ytlQ - - - - - - -
MKBDJGCF_01960 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MKBDJGCF_01961 3.42e-198 ytmP - - M - - - Phosphotransferase
MKBDJGCF_01962 4.54e-59 ytzH - - S - - - YtzH-like protein
MKBDJGCF_01963 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKBDJGCF_01964 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MKBDJGCF_01965 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MKBDJGCF_01966 9.96e-69 ytzB - - S - - - small secreted protein
MKBDJGCF_01967 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MKBDJGCF_01968 9.21e-99 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MKBDJGCF_01969 2.23e-75 ytpP - - CO - - - Thioredoxin
MKBDJGCF_01970 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
MKBDJGCF_01971 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKBDJGCF_01972 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MKBDJGCF_01973 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MKBDJGCF_01974 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKBDJGCF_01975 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MKBDJGCF_01976 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
MKBDJGCF_01977 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MKBDJGCF_01978 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MKBDJGCF_01979 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MKBDJGCF_01980 1.87e-127 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MKBDJGCF_01981 8.46e-285 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MKBDJGCF_01982 1.43e-139 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MKBDJGCF_01983 3.32e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MKBDJGCF_01984 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKBDJGCF_01985 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKBDJGCF_01986 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MKBDJGCF_01987 7.21e-154 ygaZ - - E - - - AzlC protein
MKBDJGCF_01988 1.06e-188 - - - K - - - Transcriptional regulator
MKBDJGCF_01989 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKBDJGCF_01990 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MKBDJGCF_01992 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MKBDJGCF_01994 2.12e-273 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKBDJGCF_01995 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKBDJGCF_01996 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MKBDJGCF_01997 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MKBDJGCF_01998 2.22e-137 yttP - - K - - - Transcriptional regulator
MKBDJGCF_01999 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MKBDJGCF_02000 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKBDJGCF_02001 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MKBDJGCF_02002 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MKBDJGCF_02003 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKBDJGCF_02004 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MKBDJGCF_02005 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKBDJGCF_02006 0.0 ytcJ - - S - - - amidohydrolase
MKBDJGCF_02007 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKBDJGCF_02008 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MKBDJGCF_02009 1.31e-103 yteJ - - S - - - RDD family
MKBDJGCF_02010 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
MKBDJGCF_02011 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
MKBDJGCF_02012 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKBDJGCF_02013 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MKBDJGCF_02014 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKBDJGCF_02015 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MKBDJGCF_02016 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKBDJGCF_02017 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MKBDJGCF_02019 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_02020 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
MKBDJGCF_02021 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
MKBDJGCF_02022 3.44e-60 ytpI - - S - - - YtpI-like protein
MKBDJGCF_02023 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MKBDJGCF_02024 1.17e-30 - - - - - - - -
MKBDJGCF_02025 3.08e-113 ytrI - - - - - - -
MKBDJGCF_02026 9.23e-71 ytrH - - S - - - Sporulation protein YtrH
MKBDJGCF_02027 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MKBDJGCF_02028 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MKBDJGCF_02029 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKBDJGCF_02030 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MKBDJGCF_02031 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKBDJGCF_02032 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MKBDJGCF_02033 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MKBDJGCF_02034 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
MKBDJGCF_02035 1.14e-95 ytwI - - S - - - membrane
MKBDJGCF_02036 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MKBDJGCF_02037 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MKBDJGCF_02038 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MKBDJGCF_02039 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_02040 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MKBDJGCF_02041 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKBDJGCF_02042 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKBDJGCF_02043 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
MKBDJGCF_02044 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKBDJGCF_02045 4.68e-198 ytbE - - S - - - reductase
MKBDJGCF_02046 3.31e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MKBDJGCF_02047 7.74e-86 ytcD - - K - - - Transcriptional regulator
MKBDJGCF_02048 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKBDJGCF_02049 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKBDJGCF_02050 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKBDJGCF_02051 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MKBDJGCF_02052 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MKBDJGCF_02053 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
MKBDJGCF_02054 6.12e-192 ytxC - - S - - - YtxC-like family
MKBDJGCF_02055 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKBDJGCF_02056 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MKBDJGCF_02057 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02058 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MKBDJGCF_02059 3.04e-64 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
MKBDJGCF_02060 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKBDJGCF_02061 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKBDJGCF_02062 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MKBDJGCF_02063 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKBDJGCF_02064 5.91e-51 ysdA - - S - - - Membrane
MKBDJGCF_02065 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
MKBDJGCF_02066 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MKBDJGCF_02067 4.34e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MKBDJGCF_02068 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MKBDJGCF_02069 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MKBDJGCF_02070 2.82e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MKBDJGCF_02071 1.33e-175 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MKBDJGCF_02072 2.36e-269 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MKBDJGCF_02073 2.69e-312 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MKBDJGCF_02074 8.11e-211 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
MKBDJGCF_02075 1.27e-186 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MKBDJGCF_02076 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MKBDJGCF_02077 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MKBDJGCF_02078 6.09e-310 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MKBDJGCF_02079 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
MKBDJGCF_02080 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MKBDJGCF_02081 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MKBDJGCF_02082 1.94e-165 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKBDJGCF_02083 1.27e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKBDJGCF_02084 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKBDJGCF_02085 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKBDJGCF_02086 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKBDJGCF_02087 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
MKBDJGCF_02088 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MKBDJGCF_02089 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKBDJGCF_02090 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
MKBDJGCF_02091 6.57e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
MKBDJGCF_02092 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKBDJGCF_02093 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_02094 2.18e-172 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MKBDJGCF_02095 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MKBDJGCF_02096 4.79e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MKBDJGCF_02097 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MKBDJGCF_02098 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MKBDJGCF_02099 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKBDJGCF_02100 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MKBDJGCF_02101 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
MKBDJGCF_02102 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MKBDJGCF_02103 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MKBDJGCF_02104 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MKBDJGCF_02105 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MKBDJGCF_02106 3.34e-80 - - - S - - - dUTPase
MKBDJGCF_02107 4.41e-08 - - - S - - - YopX protein
MKBDJGCF_02108 2.39e-14 - - - FG - - - Mazg nucleotide pyrophosphohydrolase
MKBDJGCF_02110 1.09e-61 - - - - - - - -
MKBDJGCF_02113 4.82e-87 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKBDJGCF_02114 3.94e-58 - - - S - - - dUTPase
MKBDJGCF_02117 2.62e-08 - - - S - - - YopX protein
MKBDJGCF_02122 2.97e-59 - - - - - - - -
MKBDJGCF_02124 1.76e-22 - - - V - - - VanZ like family
MKBDJGCF_02125 4.82e-87 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKBDJGCF_02127 1.74e-17 - - - K - - - Transcriptional regulator
MKBDJGCF_02129 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MKBDJGCF_02130 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MKBDJGCF_02131 7.32e-105 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MKBDJGCF_02132 1.42e-102 yuaE - - S - - - DinB superfamily
MKBDJGCF_02133 1.21e-134 - - - S - - - MOSC domain
MKBDJGCF_02134 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MKBDJGCF_02135 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MKBDJGCF_02136 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MKBDJGCF_02137 4.6e-119 yuaB - - - - - - -
MKBDJGCF_02138 8.02e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MKBDJGCF_02139 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKBDJGCF_02140 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKBDJGCF_02141 2.36e-47 - - - G - - - Cupin
MKBDJGCF_02142 2.17e-57 yjcN - - - - - - -
MKBDJGCF_02145 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
MKBDJGCF_02146 7.36e-20 - - - - - - - -
MKBDJGCF_02148 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKBDJGCF_02149 2.73e-248 yubA - - S - - - transporter activity
MKBDJGCF_02150 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MKBDJGCF_02151 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MKBDJGCF_02152 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MKBDJGCF_02153 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MKBDJGCF_02154 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MKBDJGCF_02155 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MKBDJGCF_02156 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MKBDJGCF_02157 1.82e-52 - - - - - - - -
MKBDJGCF_02158 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MKBDJGCF_02159 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MKBDJGCF_02160 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MKBDJGCF_02161 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MKBDJGCF_02162 3.56e-22 - - - - - - - -
MKBDJGCF_02163 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
MKBDJGCF_02164 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MKBDJGCF_02165 4.57e-90 yugN - - S - - - YugN-like family
MKBDJGCF_02167 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MKBDJGCF_02168 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MKBDJGCF_02169 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MKBDJGCF_02170 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MKBDJGCF_02171 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MKBDJGCF_02172 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MKBDJGCF_02173 1.53e-108 alaR - - K - - - Transcriptional regulator
MKBDJGCF_02174 3.41e-192 yugF - - I - - - Hydrolase
MKBDJGCF_02175 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
MKBDJGCF_02176 2.21e-275 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MKBDJGCF_02177 5e-278 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02178 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MKBDJGCF_02179 2.54e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MKBDJGCF_02180 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
MKBDJGCF_02181 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MKBDJGCF_02182 5.95e-92 yuxK - - S - - - protein conserved in bacteria
MKBDJGCF_02183 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
MKBDJGCF_02184 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MKBDJGCF_02185 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MKBDJGCF_02186 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MKBDJGCF_02187 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_02188 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MKBDJGCF_02189 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MKBDJGCF_02191 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKBDJGCF_02192 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKBDJGCF_02193 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKBDJGCF_02194 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKBDJGCF_02195 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKBDJGCF_02196 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKBDJGCF_02197 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MKBDJGCF_02198 3.29e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKBDJGCF_02199 1.19e-315 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02201 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
MKBDJGCF_02202 1.87e-11 - - - S - - - DegQ (SacQ) family
MKBDJGCF_02203 1.59e-62 yuzC - - - - - - -
MKBDJGCF_02204 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MKBDJGCF_02205 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKBDJGCF_02206 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MKBDJGCF_02207 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
MKBDJGCF_02208 1.1e-50 yueH - - S - - - YueH-like protein
MKBDJGCF_02209 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MKBDJGCF_02210 5.91e-233 yueF - - S - - - transporter activity
MKBDJGCF_02211 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
MKBDJGCF_02212 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MKBDJGCF_02213 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_02214 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
MKBDJGCF_02215 0.0 yueB - - S - - - type VII secretion protein EsaA
MKBDJGCF_02216 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKBDJGCF_02217 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MKBDJGCF_02218 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MKBDJGCF_02219 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
MKBDJGCF_02220 1.66e-288 yukF - - QT - - - Transcriptional regulator
MKBDJGCF_02221 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MKBDJGCF_02222 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MKBDJGCF_02223 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MKBDJGCF_02224 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_02225 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MKBDJGCF_02226 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MKBDJGCF_02227 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MKBDJGCF_02228 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_02229 2.31e-198 eSD - - S ko:K07017 - ko00000 Putative esterase
MKBDJGCF_02230 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MKBDJGCF_02231 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MKBDJGCF_02232 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MKBDJGCF_02233 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKBDJGCF_02234 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MKBDJGCF_02235 2.23e-149 yuiC - - S - - - protein conserved in bacteria
MKBDJGCF_02236 1.21e-45 yuiB - - S - - - Putative membrane protein
MKBDJGCF_02237 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MKBDJGCF_02238 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MKBDJGCF_02240 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKBDJGCF_02241 1.57e-37 - - - - - - - -
MKBDJGCF_02242 5.41e-87 - - - CP - - - Membrane
MKBDJGCF_02243 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MKBDJGCF_02245 1.25e-42 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
MKBDJGCF_02247 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MKBDJGCF_02248 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_02249 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MKBDJGCF_02250 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKBDJGCF_02251 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKBDJGCF_02252 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
MKBDJGCF_02253 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MKBDJGCF_02254 2.61e-70 yuzD - - S - - - protein conserved in bacteria
MKBDJGCF_02255 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MKBDJGCF_02256 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MKBDJGCF_02257 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKBDJGCF_02258 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKBDJGCF_02259 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MKBDJGCF_02260 5.56e-244 yutH - - S - - - Spore coat protein
MKBDJGCF_02261 1.07e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MKBDJGCF_02262 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKBDJGCF_02263 3e-93 yutE - - S - - - Protein of unknown function DUF86
MKBDJGCF_02264 3.71e-62 yutD - - S - - - protein conserved in bacteria
MKBDJGCF_02265 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKBDJGCF_02266 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MKBDJGCF_02267 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MKBDJGCF_02268 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MKBDJGCF_02269 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MKBDJGCF_02270 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
MKBDJGCF_02271 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
MKBDJGCF_02272 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MKBDJGCF_02273 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MKBDJGCF_02274 6.3e-86 - - - - - - - -
MKBDJGCF_02275 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_02276 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MKBDJGCF_02277 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKBDJGCF_02278 3.33e-209 bsn - - L - - - Ribonuclease
MKBDJGCF_02279 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_02280 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MKBDJGCF_02281 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MKBDJGCF_02282 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MKBDJGCF_02283 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKBDJGCF_02284 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MKBDJGCF_02285 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MKBDJGCF_02286 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
MKBDJGCF_02288 1.66e-96 - - - - - - - -
MKBDJGCF_02289 2.77e-27 - - - S - - - Sporulation delaying protein SdpA
MKBDJGCF_02291 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MKBDJGCF_02292 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MKBDJGCF_02293 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
MKBDJGCF_02294 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
MKBDJGCF_02295 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MKBDJGCF_02296 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MKBDJGCF_02297 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MKBDJGCF_02298 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKBDJGCF_02299 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MKBDJGCF_02300 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MKBDJGCF_02302 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKBDJGCF_02303 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MKBDJGCF_02304 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MKBDJGCF_02305 1.51e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKBDJGCF_02306 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
MKBDJGCF_02307 2.25e-70 yusE - - CO - - - Thioredoxin
MKBDJGCF_02308 6.99e-79 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MKBDJGCF_02309 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
MKBDJGCF_02310 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MKBDJGCF_02311 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MKBDJGCF_02312 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MKBDJGCF_02313 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MKBDJGCF_02314 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MKBDJGCF_02315 1.72e-10 - - - S - - - YuzL-like protein
MKBDJGCF_02316 5.15e-191 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MKBDJGCF_02317 7.03e-53 - - - - - - - -
MKBDJGCF_02318 3.53e-69 yusN - - M - - - Coat F domain
MKBDJGCF_02319 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MKBDJGCF_02320 0.0 yusP - - P - - - Major facilitator superfamily
MKBDJGCF_02321 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
MKBDJGCF_02322 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_02323 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MKBDJGCF_02324 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
MKBDJGCF_02325 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKBDJGCF_02326 2.79e-62 - - - S - - - YusW-like protein
MKBDJGCF_02327 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MKBDJGCF_02328 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_02329 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MKBDJGCF_02330 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKBDJGCF_02331 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_02332 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02333 2.68e-32 - - - - - - - -
MKBDJGCF_02334 6.7e-196 yuxN - - K - - - Transcriptional regulator
MKBDJGCF_02335 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKBDJGCF_02336 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
MKBDJGCF_02337 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MKBDJGCF_02338 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MKBDJGCF_02339 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MKBDJGCF_02340 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKBDJGCF_02341 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02342 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MKBDJGCF_02343 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MKBDJGCF_02344 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MKBDJGCF_02345 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MKBDJGCF_02346 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_02347 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MKBDJGCF_02348 1.87e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MKBDJGCF_02349 5.73e-224 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_02350 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MKBDJGCF_02351 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_02352 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MKBDJGCF_02353 0.0 yvrG - - T - - - Histidine kinase
MKBDJGCF_02354 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_02355 1.14e-48 - - - - - - - -
MKBDJGCF_02356 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MKBDJGCF_02357 1.88e-21 - - - S - - - YvrJ protein family
MKBDJGCF_02358 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MKBDJGCF_02359 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
MKBDJGCF_02360 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MKBDJGCF_02361 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_02362 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_02363 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MKBDJGCF_02364 2.17e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKBDJGCF_02365 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MKBDJGCF_02366 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MKBDJGCF_02367 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MKBDJGCF_02368 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MKBDJGCF_02369 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MKBDJGCF_02370 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MKBDJGCF_02371 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MKBDJGCF_02372 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MKBDJGCF_02373 2.17e-146 yfiK - - K - - - Regulator
MKBDJGCF_02374 3.01e-237 - - - T - - - Histidine kinase
MKBDJGCF_02375 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MKBDJGCF_02376 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MKBDJGCF_02377 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MKBDJGCF_02378 1.2e-198 yvgN - - S - - - reductase
MKBDJGCF_02379 6.3e-110 yvgO - - - - - - -
MKBDJGCF_02380 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MKBDJGCF_02381 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MKBDJGCF_02382 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKBDJGCF_02383 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MKBDJGCF_02384 9.04e-130 yvgT - - S - - - membrane
MKBDJGCF_02385 8.69e-187 - - - S - - - Metallo-peptidase family M12
MKBDJGCF_02386 2.51e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MKBDJGCF_02387 4.84e-133 bdbD - - O - - - Thioredoxin
MKBDJGCF_02388 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MKBDJGCF_02389 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MKBDJGCF_02390 1.09e-38 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
MKBDJGCF_02391 2.05e-61 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MKBDJGCF_02392 3.08e-243 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MKBDJGCF_02393 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKBDJGCF_02394 2.7e-313 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_02395 9.38e-58 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MKBDJGCF_02396 1.65e-221 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_02397 2.03e-177 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MKBDJGCF_02398 6.21e-151 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKBDJGCF_02399 9.1e-151 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKBDJGCF_02400 5.62e-185 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MKBDJGCF_02401 1.81e-164 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MKBDJGCF_02402 1.57e-128 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MKBDJGCF_02403 3.97e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MKBDJGCF_02404 3.93e-178 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MKBDJGCF_02405 1.1e-54 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MKBDJGCF_02407 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKBDJGCF_02408 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKBDJGCF_02409 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MKBDJGCF_02410 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MKBDJGCF_02411 1.64e-47 yvzC - - K - - - transcriptional
MKBDJGCF_02412 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MKBDJGCF_02413 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MKBDJGCF_02414 1.17e-67 yvaP - - K - - - transcriptional
MKBDJGCF_02415 8.25e-307 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MKBDJGCF_02416 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MKBDJGCF_02417 1.93e-167 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MKBDJGCF_02418 1.35e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MKBDJGCF_02419 1.73e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_02420 4.05e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MKBDJGCF_02421 4.75e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKBDJGCF_02422 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MKBDJGCF_02423 1.25e-262 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKBDJGCF_02424 3.5e-108 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MKBDJGCF_02425 2.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MKBDJGCF_02426 2.99e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKBDJGCF_02427 5.4e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MKBDJGCF_02428 1.21e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKBDJGCF_02429 2.67e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MKBDJGCF_02430 1.55e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MKBDJGCF_02431 2.61e-148 yvbI - - M - - - Membrane
MKBDJGCF_02432 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MKBDJGCF_02433 5.07e-103 yvbK - - K - - - acetyltransferase
MKBDJGCF_02434 4.16e-260 - - - EGP - - - Major facilitator Superfamily
MKBDJGCF_02435 1.87e-219 - - - - - - - -
MKBDJGCF_02436 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
MKBDJGCF_02437 1.13e-182 - - - C - - - WbqC-like protein family
MKBDJGCF_02438 2.49e-179 - - - M - - - Protein involved in cellulose biosynthesis
MKBDJGCF_02439 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKBDJGCF_02440 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MKBDJGCF_02441 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MKBDJGCF_02442 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKBDJGCF_02443 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MKBDJGCF_02444 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKBDJGCF_02445 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MKBDJGCF_02446 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKBDJGCF_02447 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MKBDJGCF_02448 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKBDJGCF_02449 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKBDJGCF_02451 2.95e-268 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKBDJGCF_02452 6.86e-255 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MKBDJGCF_02453 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_02454 5.29e-161 yvbU - - K - - - Transcriptional regulator
MKBDJGCF_02455 5.35e-196 yvbV - - EG - - - EamA-like transporter family
MKBDJGCF_02456 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_02458 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
MKBDJGCF_02459 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MKBDJGCF_02460 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MKBDJGCF_02461 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKBDJGCF_02462 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MKBDJGCF_02463 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKBDJGCF_02464 3.33e-172 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_02465 5.05e-76 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_02466 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MKBDJGCF_02467 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MKBDJGCF_02468 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MKBDJGCF_02469 4.01e-44 yvfG - - S - - - YvfG protein
MKBDJGCF_02470 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MKBDJGCF_02471 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MKBDJGCF_02472 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MKBDJGCF_02473 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKBDJGCF_02474 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_02475 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_02476 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MKBDJGCF_02477 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MKBDJGCF_02478 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MKBDJGCF_02479 1.95e-253 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MKBDJGCF_02480 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_02481 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MKBDJGCF_02482 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MKBDJGCF_02483 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MKBDJGCF_02484 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MKBDJGCF_02485 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MKBDJGCF_02486 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MKBDJGCF_02488 8.3e-111 ywjB - - H - - - RibD C-terminal domain
MKBDJGCF_02489 4.2e-164 - - - CH - - - FAD binding domain
MKBDJGCF_02490 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
MKBDJGCF_02491 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
MKBDJGCF_02492 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKBDJGCF_02493 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MKBDJGCF_02494 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
MKBDJGCF_02495 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
MKBDJGCF_02496 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
MKBDJGCF_02497 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
MKBDJGCF_02498 0.0 - - - I - - - Pfam Lipase (class 3)
MKBDJGCF_02499 3.08e-44 - - - - - - - -
MKBDJGCF_02501 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MKBDJGCF_02502 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MKBDJGCF_02503 9.34e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MKBDJGCF_02504 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKBDJGCF_02505 1.4e-202 yraN - - K - - - Transcriptional regulator
MKBDJGCF_02506 3.16e-258 yraM - - S - - - PrpF protein
MKBDJGCF_02507 6.64e-313 - - - EGP - - - Sugar (and other) transporter
MKBDJGCF_02508 1.06e-110 - - - - - - - -
MKBDJGCF_02509 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MKBDJGCF_02510 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MKBDJGCF_02511 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MKBDJGCF_02512 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MKBDJGCF_02513 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKBDJGCF_02514 4.11e-100 - - - M - - - Ribonuclease
MKBDJGCF_02515 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MKBDJGCF_02516 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MKBDJGCF_02517 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MKBDJGCF_02518 3.51e-223 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MKBDJGCF_02519 1.41e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MKBDJGCF_02520 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKBDJGCF_02521 4.78e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKBDJGCF_02522 4.88e-195 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MKBDJGCF_02523 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MKBDJGCF_02524 1.01e-231 sasA - - T - - - Histidine kinase
MKBDJGCF_02525 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_02526 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MKBDJGCF_02527 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MKBDJGCF_02528 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKBDJGCF_02529 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKBDJGCF_02530 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKBDJGCF_02531 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MKBDJGCF_02532 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKBDJGCF_02533 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKBDJGCF_02534 9.79e-260 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKBDJGCF_02535 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
MKBDJGCF_02536 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MKBDJGCF_02537 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MKBDJGCF_02538 2.06e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKBDJGCF_02539 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKBDJGCF_02540 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKBDJGCF_02541 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKBDJGCF_02542 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MKBDJGCF_02543 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MKBDJGCF_02544 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MKBDJGCF_02545 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
MKBDJGCF_02546 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MKBDJGCF_02547 4.14e-214 yvlB - - S - - - Putative adhesin
MKBDJGCF_02548 1.79e-61 yvlA - - - - - - -
MKBDJGCF_02549 1.29e-40 yvkN - - - - - - -
MKBDJGCF_02550 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKBDJGCF_02551 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKBDJGCF_02552 2.59e-45 csbA - - S - - - protein conserved in bacteria
MKBDJGCF_02553 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MKBDJGCF_02554 1.12e-119 yvkB - - K - - - Transcriptional regulator
MKBDJGCF_02555 3.49e-290 yvkA - - P - - - -transporter
MKBDJGCF_02558 7.71e-276 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKBDJGCF_02559 5.83e-72 swrA - - S - - - Swarming motility protein
MKBDJGCF_02560 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MKBDJGCF_02561 5.2e-276 ywoF - - P - - - Right handed beta helix region
MKBDJGCF_02562 5e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MKBDJGCF_02563 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MKBDJGCF_02564 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MKBDJGCF_02565 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_02566 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKBDJGCF_02567 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKBDJGCF_02568 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKBDJGCF_02569 1.92e-89 - - - - - - - -
MKBDJGCF_02570 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MKBDJGCF_02571 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MKBDJGCF_02572 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKBDJGCF_02573 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKBDJGCF_02574 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKBDJGCF_02575 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKBDJGCF_02576 1.48e-103 yviE - - - - - - -
MKBDJGCF_02577 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MKBDJGCF_02578 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MKBDJGCF_02579 1.43e-101 yvyG - - NOU - - - FlgN protein
MKBDJGCF_02580 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MKBDJGCF_02581 6.15e-95 yvyF - - S - - - flagellar protein
MKBDJGCF_02582 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MKBDJGCF_02583 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MKBDJGCF_02584 5.41e-316 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKBDJGCF_02585 3.16e-197 degV - - S - - - protein conserved in bacteria
MKBDJGCF_02586 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKBDJGCF_02587 2.31e-245 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKBDJGCF_02588 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MKBDJGCF_02589 9.24e-234 yvhJ - - K - - - Transcriptional regulator
MKBDJGCF_02590 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MKBDJGCF_02591 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MKBDJGCF_02592 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MKBDJGCF_02593 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MKBDJGCF_02594 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MKBDJGCF_02595 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKBDJGCF_02596 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MKBDJGCF_02597 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_02598 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKBDJGCF_02599 1.27e-267 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_02600 0.0 lytB - - D - - - Stage II sporulation protein
MKBDJGCF_02601 1.99e-39 - - - - - - - -
MKBDJGCF_02602 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKBDJGCF_02603 4.2e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKBDJGCF_02604 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MKBDJGCF_02605 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKBDJGCF_02606 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MKBDJGCF_02607 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKBDJGCF_02608 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
MKBDJGCF_02609 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MKBDJGCF_02610 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKBDJGCF_02611 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKBDJGCF_02612 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKBDJGCF_02613 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MKBDJGCF_02614 9.27e-172 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MKBDJGCF_02615 3.58e-99 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MKBDJGCF_02616 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MKBDJGCF_02617 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MKBDJGCF_02618 1.37e-305 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
MKBDJGCF_02619 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKBDJGCF_02620 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
MKBDJGCF_02621 2.21e-194 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MKBDJGCF_02622 1.4e-60 yttA - - S - - - Pfam Transposase IS66
MKBDJGCF_02623 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKBDJGCF_02624 1.16e-28 ywtC - - - - - - -
MKBDJGCF_02625 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MKBDJGCF_02626 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MKBDJGCF_02627 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MKBDJGCF_02628 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MKBDJGCF_02629 6.95e-228 - - - E - - - Spore germination protein
MKBDJGCF_02630 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MKBDJGCF_02631 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MKBDJGCF_02632 7.26e-220 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MKBDJGCF_02633 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKBDJGCF_02634 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKBDJGCF_02635 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKBDJGCF_02636 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MKBDJGCF_02637 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MKBDJGCF_02638 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
MKBDJGCF_02639 3.96e-114 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MKBDJGCF_02640 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MKBDJGCF_02641 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MKBDJGCF_02642 6.98e-211 alsR - - K - - - LysR substrate binding domain
MKBDJGCF_02643 1.69e-296 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKBDJGCF_02644 8.96e-150 ywrJ - - - - - - -
MKBDJGCF_02645 4.38e-157 cotB - - - ko:K06325 - ko00000 -
MKBDJGCF_02646 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
MKBDJGCF_02647 6.86e-13 - - - - - - - -
MKBDJGCF_02648 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKBDJGCF_02650 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MKBDJGCF_02651 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MKBDJGCF_02652 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MKBDJGCF_02653 2.89e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MKBDJGCF_02654 1.29e-130 - - - - - - - -
MKBDJGCF_02655 7.15e-83 - - - - - - - -
MKBDJGCF_02656 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
MKBDJGCF_02657 1.92e-25 - - - - - - - -
MKBDJGCF_02658 2.19e-75 - - - S - - - SUKH-4 immunity protein
MKBDJGCF_02659 3.1e-288 ywqJ - - S - - - Pre-toxin TG
MKBDJGCF_02660 1.59e-47 ywqI - - S - - - Family of unknown function (DUF5344)
MKBDJGCF_02662 1.68e-182 ywqG - - S - - - Domain of unknown function (DUF1963)
MKBDJGCF_02663 2.45e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKBDJGCF_02664 6.3e-174 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MKBDJGCF_02665 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MKBDJGCF_02666 1.2e-143 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MKBDJGCF_02667 3e-22 - - - - - - - -
MKBDJGCF_02668 0.0 ywqB - - S - - - SWIM zinc finger
MKBDJGCF_02669 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKBDJGCF_02670 7.72e-195 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MKBDJGCF_02671 5.39e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MKBDJGCF_02672 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MKBDJGCF_02673 1.83e-74 ywpG - - - - - - -
MKBDJGCF_02674 1.79e-89 ywpF - - S - - - YwpF-like protein
MKBDJGCF_02675 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKBDJGCF_02676 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKBDJGCF_02677 1.47e-245 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MKBDJGCF_02678 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MKBDJGCF_02679 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MKBDJGCF_02680 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MKBDJGCF_02681 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MKBDJGCF_02682 5.3e-93 ywoH - - K - - - transcriptional
MKBDJGCF_02683 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_02684 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MKBDJGCF_02685 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
MKBDJGCF_02686 2.1e-128 yjgF - - Q - - - Isochorismatase family
MKBDJGCF_02687 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MKBDJGCF_02688 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MKBDJGCF_02689 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MKBDJGCF_02690 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MKBDJGCF_02691 3.41e-88 ywnJ - - S - - - VanZ like family
MKBDJGCF_02692 1.17e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MKBDJGCF_02693 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MKBDJGCF_02695 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
MKBDJGCF_02696 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKBDJGCF_02697 1.12e-21 yqgA - - - - - - -
MKBDJGCF_02698 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
MKBDJGCF_02699 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MKBDJGCF_02700 3.09e-88 ywnA - - K - - - Transcriptional regulator
MKBDJGCF_02701 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MKBDJGCF_02702 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MKBDJGCF_02703 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MKBDJGCF_02704 2.41e-16 csbD - - K - - - CsbD-like
MKBDJGCF_02705 1.01e-105 ywmF - - S - - - Peptidase M50
MKBDJGCF_02706 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MKBDJGCF_02707 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKBDJGCF_02708 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKBDJGCF_02710 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MKBDJGCF_02711 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MKBDJGCF_02712 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MKBDJGCF_02713 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKBDJGCF_02714 1.27e-169 ywmB - - S - - - TATA-box binding
MKBDJGCF_02715 1.85e-44 ywzB - - S - - - membrane
MKBDJGCF_02716 1.98e-115 ywmA - - - - - - -
MKBDJGCF_02717 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MKBDJGCF_02718 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKBDJGCF_02719 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKBDJGCF_02720 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKBDJGCF_02721 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKBDJGCF_02722 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKBDJGCF_02723 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKBDJGCF_02724 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MKBDJGCF_02725 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MKBDJGCF_02726 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKBDJGCF_02727 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKBDJGCF_02728 8.33e-122 ywlG - - S - - - Belongs to the UPF0340 family
MKBDJGCF_02729 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MKBDJGCF_02730 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKBDJGCF_02731 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
MKBDJGCF_02732 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKBDJGCF_02733 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MKBDJGCF_02734 1.73e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MKBDJGCF_02735 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MKBDJGCF_02737 3.54e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKBDJGCF_02738 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKBDJGCF_02739 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_02740 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MKBDJGCF_02741 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MKBDJGCF_02742 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MKBDJGCF_02743 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MKBDJGCF_02744 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MKBDJGCF_02745 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKBDJGCF_02746 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MKBDJGCF_02747 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKBDJGCF_02748 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKBDJGCF_02749 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MKBDJGCF_02750 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MKBDJGCF_02751 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
MKBDJGCF_02752 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKBDJGCF_02753 1.53e-71 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKBDJGCF_02754 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MKBDJGCF_02755 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MKBDJGCF_02756 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MKBDJGCF_02757 3.23e-58 ywjC - - - - - - -
MKBDJGCF_02758 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MKBDJGCF_02759 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKBDJGCF_02760 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MKBDJGCF_02761 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MKBDJGCF_02762 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MKBDJGCF_02763 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKBDJGCF_02764 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MKBDJGCF_02765 8.59e-162 ywiC - - S - - - YwiC-like protein
MKBDJGCF_02766 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MKBDJGCF_02767 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MKBDJGCF_02768 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MKBDJGCF_02769 4.46e-94 ywiB - - S - - - protein conserved in bacteria
MKBDJGCF_02771 1.55e-248 ywhL - - CO - - - amine dehydrogenase activity
MKBDJGCF_02772 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MKBDJGCF_02774 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MKBDJGCF_02775 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKBDJGCF_02776 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MKBDJGCF_02777 1.96e-93 - - - - - - - -
MKBDJGCF_02778 2.07e-116 ywhD - - S - - - YwhD family
MKBDJGCF_02779 1.1e-152 ywhC - - S - - - Peptidase family M50
MKBDJGCF_02780 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MKBDJGCF_02781 3.29e-90 ywhA - - K - - - Transcriptional regulator
MKBDJGCF_02782 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
MKBDJGCF_02783 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
MKBDJGCF_02784 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MKBDJGCF_02785 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MKBDJGCF_02786 6.18e-139 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MKBDJGCF_02788 4.25e-65 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
MKBDJGCF_02789 7.2e-109 - - - S - - - membrane
MKBDJGCF_02790 1.29e-117 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_02791 4.46e-54 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_02792 3.03e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
MKBDJGCF_02795 6.53e-210 - - - - - - - -
MKBDJGCF_02797 1.33e-196 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MKBDJGCF_02798 6.57e-200 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_02799 6.26e-205 - - - S - - - Conserved hypothetical protein 698
MKBDJGCF_02800 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MKBDJGCF_02801 2.22e-183 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MKBDJGCF_02802 2.12e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MKBDJGCF_02803 1.6e-290 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MKBDJGCF_02804 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MKBDJGCF_02805 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MKBDJGCF_02806 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_02807 4.67e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MKBDJGCF_02808 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MKBDJGCF_02809 1.14e-276 ywfA - - EGP - - - -transporter
MKBDJGCF_02810 9.06e-238 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MKBDJGCF_02811 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MKBDJGCF_02812 0.0 rocB - - E - - - arginine degradation protein
MKBDJGCF_02813 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKBDJGCF_02814 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MKBDJGCF_02815 4.02e-80 - - - - - - - -
MKBDJGCF_02816 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MKBDJGCF_02817 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKBDJGCF_02818 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKBDJGCF_02819 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKBDJGCF_02820 3.15e-214 spsG - - M - - - Spore Coat
MKBDJGCF_02821 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
MKBDJGCF_02822 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MKBDJGCF_02823 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MKBDJGCF_02824 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MKBDJGCF_02825 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MKBDJGCF_02826 4.13e-180 spsA - - M - - - Spore Coat
MKBDJGCF_02827 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MKBDJGCF_02828 4.39e-76 ywdK - - S - - - small membrane protein
MKBDJGCF_02829 8.52e-288 ywdJ - - F - - - Xanthine uracil
MKBDJGCF_02830 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
MKBDJGCF_02831 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKBDJGCF_02832 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
MKBDJGCF_02834 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MKBDJGCF_02835 6.09e-27 ywdA - - - - - - -
MKBDJGCF_02836 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MKBDJGCF_02837 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_02838 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MKBDJGCF_02840 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKBDJGCF_02841 2.49e-231 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_02842 1.26e-150 - - - K - - - WYL domain
MKBDJGCF_02843 8.59e-162 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_02844 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
MKBDJGCF_02845 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
MKBDJGCF_02846 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MKBDJGCF_02847 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MKBDJGCF_02848 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MKBDJGCF_02849 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MKBDJGCF_02850 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MKBDJGCF_02851 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MKBDJGCF_02852 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKBDJGCF_02853 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MKBDJGCF_02854 5.74e-48 ydaS - - S - - - membrane
MKBDJGCF_02855 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MKBDJGCF_02856 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKBDJGCF_02857 7.8e-78 gtcA - - S - - - GtrA-like protein
MKBDJGCF_02858 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MKBDJGCF_02860 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
MKBDJGCF_02861 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
MKBDJGCF_02862 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MKBDJGCF_02863 9.8e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MKBDJGCF_02864 5.83e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MKBDJGCF_02865 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MKBDJGCF_02866 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKBDJGCF_02867 2.45e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKBDJGCF_02868 2.29e-200 ywbI - - K - - - Transcriptional regulator
MKBDJGCF_02869 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MKBDJGCF_02870 6.2e-142 ywbG - - M - - - effector of murein hydrolase
MKBDJGCF_02871 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MKBDJGCF_02872 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MKBDJGCF_02873 1.97e-200 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MKBDJGCF_02874 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MKBDJGCF_02875 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MKBDJGCF_02876 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKBDJGCF_02877 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKBDJGCF_02878 2.87e-205 gspA - - M - - - General stress
MKBDJGCF_02880 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MKBDJGCF_02881 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MKBDJGCF_02882 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MKBDJGCF_02883 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_02884 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MKBDJGCF_02885 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_02886 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKBDJGCF_02887 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MKBDJGCF_02888 4.7e-316 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKBDJGCF_02889 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_02890 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKBDJGCF_02891 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MKBDJGCF_02892 2.88e-286 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MKBDJGCF_02893 1.95e-145 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MKBDJGCF_02894 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MKBDJGCF_02895 7.43e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_02896 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_02897 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MKBDJGCF_02898 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MKBDJGCF_02899 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKBDJGCF_02900 3.25e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_02901 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_02902 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKBDJGCF_02903 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKBDJGCF_02904 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MKBDJGCF_02905 1.05e-227 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MKBDJGCF_02906 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MKBDJGCF_02907 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MKBDJGCF_02908 2.33e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MKBDJGCF_02909 8.74e-315 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MKBDJGCF_02910 3.54e-191 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKBDJGCF_02911 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MKBDJGCF_02912 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MKBDJGCF_02913 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MKBDJGCF_02914 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MKBDJGCF_02915 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
MKBDJGCF_02916 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
MKBDJGCF_02917 3.56e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_02918 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MKBDJGCF_02919 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKBDJGCF_02921 6.7e-114 yxkC - - S - - - Domain of unknown function (DUF4352)
MKBDJGCF_02922 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MKBDJGCF_02923 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MKBDJGCF_02926 3.81e-105 yxjI - - S - - - LURP-one-related
MKBDJGCF_02927 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MKBDJGCF_02928 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MKBDJGCF_02929 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKBDJGCF_02930 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
MKBDJGCF_02931 3.23e-60 yxiS - - - - - - -
MKBDJGCF_02932 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
MKBDJGCF_02933 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MKBDJGCF_02934 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MKBDJGCF_02935 9.73e-176 bglS - - M - - - licheninase activity
MKBDJGCF_02936 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MKBDJGCF_02937 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MKBDJGCF_02938 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MKBDJGCF_02940 9.75e-27 - - - - - - - -
MKBDJGCF_02942 2.79e-140 - - - - - - - -
MKBDJGCF_02943 4.23e-103 - - - - - - - -
MKBDJGCF_02944 2.91e-85 yxiG - - - - - - -
MKBDJGCF_02945 9.79e-75 yxxG - - - - - - -
MKBDJGCF_02947 6.82e-251 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MKBDJGCF_02948 7.42e-202 yxxF - - EG - - - EamA-like transporter family
MKBDJGCF_02949 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
MKBDJGCF_02950 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKBDJGCF_02951 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_02952 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MKBDJGCF_02953 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MKBDJGCF_02954 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MKBDJGCF_02955 0.0 - - - L - - - Z1 domain
MKBDJGCF_02956 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
MKBDJGCF_02957 2.49e-244 - - - S - - - AIPR protein
MKBDJGCF_02958 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MKBDJGCF_02959 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MKBDJGCF_02960 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MKBDJGCF_02961 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKBDJGCF_02962 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MKBDJGCF_02963 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MKBDJGCF_02964 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MKBDJGCF_02965 2.59e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MKBDJGCF_02966 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKBDJGCF_02967 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKBDJGCF_02968 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKBDJGCF_02969 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
MKBDJGCF_02972 9.45e-26 yxeE - - - - - - -
MKBDJGCF_02974 9.67e-33 yxeD - - - - - - -
MKBDJGCF_02975 4.86e-47 - - - - - - - -
MKBDJGCF_02976 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MKBDJGCF_02977 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
MKBDJGCF_02978 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MKBDJGCF_02979 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_02980 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02981 5.2e-156 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_02982 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MKBDJGCF_02983 2.32e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MKBDJGCF_02984 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MKBDJGCF_02985 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MKBDJGCF_02986 2.76e-289 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MKBDJGCF_02987 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MKBDJGCF_02988 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MKBDJGCF_02989 1e-224 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MKBDJGCF_02990 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MKBDJGCF_02991 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKBDJGCF_02992 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MKBDJGCF_02993 1.26e-217 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MKBDJGCF_02994 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKBDJGCF_02995 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MKBDJGCF_02996 1.28e-187 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MKBDJGCF_02997 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKBDJGCF_02998 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_02999 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MKBDJGCF_03000 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MKBDJGCF_03001 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MKBDJGCF_03002 1.22e-184 yxaL - - S - - - PQQ-like domain
MKBDJGCF_03003 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
MKBDJGCF_03004 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MKBDJGCF_03005 2.86e-251 - - - EGP - - - Major Facilitator Superfamily
MKBDJGCF_03006 8.64e-85 yxaI - - S - - - membrane protein domain
MKBDJGCF_03007 7.66e-153 - - - E - - - Ring-cleavage extradiol dioxygenase
MKBDJGCF_03008 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MKBDJGCF_03009 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MKBDJGCF_03010 9.59e-234 mrjp - - G - - - Major royal jelly protein
MKBDJGCF_03011 1.26e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MKBDJGCF_03012 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
MKBDJGCF_03013 2.97e-95 - - - K - - - Integron-associated effector binding protein
MKBDJGCF_03014 6.31e-98 yjhE - - S - - - Phage tail protein
MKBDJGCF_03019 0.0 - - - KLT - - - Protein kinase domain
MKBDJGCF_03020 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MKBDJGCF_03021 3.87e-94 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
MKBDJGCF_03022 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKBDJGCF_03023 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKBDJGCF_03024 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MKBDJGCF_03026 3.41e-178 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MKBDJGCF_03027 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MKBDJGCF_03028 7.99e-37 yfjT - - - - - - -
MKBDJGCF_03029 1.09e-277 yfkA - - S - - - YfkB-like domain
MKBDJGCF_03030 6.79e-185 yfkC - - M - - - Mechanosensitive ion channel
MKBDJGCF_03031 3.01e-181 yfkD - - S - - - YfkD-like protein
MKBDJGCF_03032 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MKBDJGCF_03033 3.65e-272 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_03034 7.59e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MKBDJGCF_03035 4.68e-64 yfkI - - S - - - gas vesicle protein
MKBDJGCF_03036 5.02e-105 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKBDJGCF_03037 7.02e-40 yfkK - - S - - - Belongs to the UPF0435 family
MKBDJGCF_03038 1.23e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_03039 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKBDJGCF_03040 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKBDJGCF_03041 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MKBDJGCF_03042 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MKBDJGCF_03043 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MKBDJGCF_03044 5.49e-235 yibE - - S - - - YibE/F-like protein
MKBDJGCF_03045 1.06e-160 yibF - - S - - - YibE/F-like protein
MKBDJGCF_03046 1.34e-154 frp - - C - - - nitroreductase
MKBDJGCF_03047 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MKBDJGCF_03048 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MKBDJGCF_03049 7.43e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_03050 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
MKBDJGCF_03051 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
MKBDJGCF_03052 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MKBDJGCF_03053 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MKBDJGCF_03054 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MKBDJGCF_03055 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MKBDJGCF_03056 3.41e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKBDJGCF_03057 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MKBDJGCF_03058 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MKBDJGCF_03059 5.69e-26 yflI - - - - - - -
MKBDJGCF_03060 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
MKBDJGCF_03061 1.9e-153 yflK - - S - - - protein conserved in bacteria
MKBDJGCF_03062 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MKBDJGCF_03063 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKBDJGCF_03064 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MKBDJGCF_03065 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MKBDJGCF_03066 1.36e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MKBDJGCF_03067 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MKBDJGCF_03068 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MKBDJGCF_03069 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MKBDJGCF_03070 0.0 - - - M - - - cell wall anchor domain
MKBDJGCF_03071 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
MKBDJGCF_03072 0.0 ywpD - - T - - - Histidine kinase
MKBDJGCF_03074 7.54e-07 - - - S - - - domain, Protein
MKBDJGCF_03075 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKBDJGCF_03076 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MKBDJGCF_03077 1.34e-174 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MKBDJGCF_03078 5.89e-314 - - - E - - - Aminotransferase class I and II
MKBDJGCF_03079 5.03e-156 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MKBDJGCF_03080 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
MKBDJGCF_03081 9.29e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MKBDJGCF_03082 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MKBDJGCF_03083 3.82e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MKBDJGCF_03084 3.54e-198 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MKBDJGCF_03085 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKBDJGCF_03086 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MKBDJGCF_03087 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MKBDJGCF_03088 8.93e-96 yclD - - - - - - -
MKBDJGCF_03089 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MKBDJGCF_03090 0.0 yclG - - M - - - Pectate lyase superfamily protein
MKBDJGCF_03092 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MKBDJGCF_03093 6.53e-290 gerKC - - S ko:K06297 - ko00000 spore germination
MKBDJGCF_03094 4.68e-242 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MKBDJGCF_03095 8.5e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKBDJGCF_03096 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKBDJGCF_03097 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MKBDJGCF_03098 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MKBDJGCF_03099 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_03100 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MKBDJGCF_03101 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
MKBDJGCF_03102 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MKBDJGCF_03103 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MKBDJGCF_03104 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_03105 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
MKBDJGCF_03106 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MKBDJGCF_03109 4.17e-314 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MKBDJGCF_03110 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_03111 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKBDJGCF_03126 0.0 - - - C - - - Na+/H+ antiporter family
MKBDJGCF_03127 2.38e-158 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MKBDJGCF_03128 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKBDJGCF_03129 3.15e-313 ygaK - - C - - - Berberine and berberine like
MKBDJGCF_03131 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
MKBDJGCF_03132 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MKBDJGCF_03133 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_03134 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03135 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03136 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MKBDJGCF_03137 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
MKBDJGCF_03138 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKBDJGCF_03139 2.34e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MKBDJGCF_03140 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MKBDJGCF_03141 1.37e-269 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MKBDJGCF_03143 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKBDJGCF_03144 2.4e-102 ygaO - - - - - - -
MKBDJGCF_03145 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_03147 1.34e-138 yhzB - - S - - - B3/4 domain
MKBDJGCF_03148 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKBDJGCF_03149 8.37e-216 yhbB - - S - - - Putative amidase domain
MKBDJGCF_03150 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKBDJGCF_03151 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
MKBDJGCF_03152 2.64e-17 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MKBDJGCF_03153 1.58e-50 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MKBDJGCF_03154 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MKBDJGCF_03155 1.23e-07 - - - - - - - -
MKBDJGCF_03156 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MKBDJGCF_03157 2.12e-276 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MKBDJGCF_03158 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MKBDJGCF_03159 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MKBDJGCF_03160 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MKBDJGCF_03161 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MKBDJGCF_03162 1.03e-65 yhcC - - - - - - -
MKBDJGCF_03163 7.54e-65 - - - - - - - -
MKBDJGCF_03164 8.78e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_03165 3.78e-148 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_03166 3.07e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_03167 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKBDJGCF_03168 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MKBDJGCF_03169 2.09e-165 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MKBDJGCF_03170 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MKBDJGCF_03171 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKBDJGCF_03172 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKBDJGCF_03173 5.08e-60 yhcM - - - - - - -
MKBDJGCF_03174 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKBDJGCF_03175 3.99e-199 yhcP - - - - - - -
MKBDJGCF_03176 2.2e-149 yhcQ - - M - - - Spore coat protein
MKBDJGCF_03177 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MKBDJGCF_03178 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MKBDJGCF_03179 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MKBDJGCF_03180 2.19e-82 yhcU - - S - - - Family of unknown function (DUF5365)
MKBDJGCF_03181 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
MKBDJGCF_03182 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
MKBDJGCF_03183 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKBDJGCF_03184 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKBDJGCF_03185 3.35e-131 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKBDJGCF_03186 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MKBDJGCF_03187 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKBDJGCF_03188 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKBDJGCF_03189 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MKBDJGCF_03190 3.71e-245 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_03191 7.97e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKBDJGCF_03192 3.01e-110 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MKBDJGCF_03193 1.16e-51 yhdB - - S - - - YhdB-like protein
MKBDJGCF_03194 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
MKBDJGCF_03195 3.78e-279 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MKBDJGCF_03196 6.05e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MKBDJGCF_03197 5.72e-314 ygxB - - M - - - Conserved TM helix
MKBDJGCF_03198 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MKBDJGCF_03199 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MKBDJGCF_03200 2.18e-164 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MKBDJGCF_03201 2.85e-193 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_03202 8.91e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MKBDJGCF_03203 2.41e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_03204 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
MKBDJGCF_03205 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKBDJGCF_03206 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
MKBDJGCF_03207 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
MKBDJGCF_03208 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MKBDJGCF_03209 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKBDJGCF_03210 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MKBDJGCF_03211 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MKBDJGCF_03212 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MKBDJGCF_03213 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKBDJGCF_03214 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MKBDJGCF_03215 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKBDJGCF_03216 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKBDJGCF_03217 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MKBDJGCF_03218 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
MKBDJGCF_03219 1.54e-251 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MKBDJGCF_03220 7.42e-174 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKBDJGCF_03221 3.96e-191 nodB1 - - G - - - deacetylase
MKBDJGCF_03222 6.34e-193 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MKBDJGCF_03223 4.2e-106 pksA - - K - - - Transcriptional regulator
MKBDJGCF_03224 1.66e-118 ymcC - - S - - - Membrane
MKBDJGCF_03225 2.39e-108 - - - T - - - universal stress protein
MKBDJGCF_03226 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MKBDJGCF_03227 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MKBDJGCF_03228 4.78e-127 yheG - - GM - - - NAD(P)H-binding
MKBDJGCF_03230 1.91e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MKBDJGCF_03231 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
MKBDJGCF_03232 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
MKBDJGCF_03233 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
MKBDJGCF_03234 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
MKBDJGCF_03235 2.72e-69 yheA - - S - - - Belongs to the UPF0342 family
MKBDJGCF_03236 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MKBDJGCF_03237 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MKBDJGCF_03238 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
MKBDJGCF_03239 7.44e-262 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MKBDJGCF_03240 1.53e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MKBDJGCF_03242 1.87e-171 yhaR - - I - - - enoyl-CoA hydratase
MKBDJGCF_03243 1.21e-20 - - - S - - - YhzD-like protein
MKBDJGCF_03244 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MKBDJGCF_03245 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MKBDJGCF_03246 3.8e-293 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MKBDJGCF_03247 0.0 yhaN - - L - - - AAA domain
MKBDJGCF_03248 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MKBDJGCF_03249 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
MKBDJGCF_03250 7.87e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKBDJGCF_03251 4.32e-122 yhaK - - S - - - Putative zincin peptidase
MKBDJGCF_03252 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
MKBDJGCF_03253 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MKBDJGCF_03254 1.58e-53 yhaH - - S - - - YtxH-like protein
MKBDJGCF_03255 2.55e-24 - - - - - - - -
MKBDJGCF_03256 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
MKBDJGCF_03257 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKBDJGCF_03258 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MKBDJGCF_03259 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MKBDJGCF_03260 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MKBDJGCF_03261 9.96e-152 ecsC - - S - - - EcsC protein family
MKBDJGCF_03262 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKBDJGCF_03263 1.65e-303 yhfA - - C - - - membrane
MKBDJGCF_03264 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MKBDJGCF_03265 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MKBDJGCF_03266 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKBDJGCF_03267 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MKBDJGCF_03268 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKBDJGCF_03269 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MKBDJGCF_03270 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MKBDJGCF_03271 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKBDJGCF_03273 1.66e-247 yhfE - - G - - - peptidase M42
MKBDJGCF_03274 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKBDJGCF_03275 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MKBDJGCF_03276 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MKBDJGCF_03277 3.92e-137 yhfK - - GM - - - NmrA-like family
MKBDJGCF_03278 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MKBDJGCF_03279 9.31e-84 yhfM - - - - - - -
MKBDJGCF_03280 1.33e-293 yhfN - - O - - - Peptidase M48
MKBDJGCF_03281 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKBDJGCF_03282 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MKBDJGCF_03283 1.59e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MKBDJGCF_03284 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MKBDJGCF_03285 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MKBDJGCF_03286 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MKBDJGCF_03287 2.08e-272 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MKBDJGCF_03288 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MKBDJGCF_03289 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_03290 5.49e-42 yhzC - - S - - - IDEAL
MKBDJGCF_03291 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MKBDJGCF_03292 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MKBDJGCF_03293 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
MKBDJGCF_03294 3.92e-157 yrpD - - S - - - Domain of unknown function, YrpD
MKBDJGCF_03295 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
MKBDJGCF_03296 2.64e-63 - - - S - - - Belongs to the UPF0145 family
MKBDJGCF_03297 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKBDJGCF_03298 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
MKBDJGCF_03299 2.3e-76 yhjD - - - - - - -
MKBDJGCF_03300 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
MKBDJGCF_03301 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MKBDJGCF_03302 0.0 yhjG - - CH - - - FAD binding domain
MKBDJGCF_03303 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_03304 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
MKBDJGCF_03305 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MKBDJGCF_03306 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
MKBDJGCF_03307 3.47e-108 yhjR - - S - - - Rubrerythrin
MKBDJGCF_03308 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
MKBDJGCF_03309 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MKBDJGCF_03310 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MKBDJGCF_03311 3.04e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKBDJGCF_03312 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MKBDJGCF_03313 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
MKBDJGCF_03314 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MKBDJGCF_03315 1.43e-78 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MKBDJGCF_03316 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MKBDJGCF_03317 3.28e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MKBDJGCF_03318 1.01e-44 gerPB - - S ko:K06300 - ko00000 cell differentiation
MKBDJGCF_03319 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MKBDJGCF_03320 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
MKBDJGCF_03321 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MKBDJGCF_03322 4.48e-78 yisL - - S - - - UPF0344 protein
MKBDJGCF_03323 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MKBDJGCF_03324 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
MKBDJGCF_03325 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MKBDJGCF_03326 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MKBDJGCF_03327 1.69e-307 yisQ - - V - - - Mate efflux family protein
MKBDJGCF_03328 1.77e-201 yisR - - K - - - Transcriptional regulator
MKBDJGCF_03329 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MKBDJGCF_03330 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MKBDJGCF_03331 3.26e-100 yisT - - S - - - DinB family
MKBDJGCF_03332 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MKBDJGCF_03333 1.49e-233 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKBDJGCF_03334 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
MKBDJGCF_03335 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
MKBDJGCF_03336 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKBDJGCF_03337 3.25e-47 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MKBDJGCF_03338 2.47e-11 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MKBDJGCF_03339 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MKBDJGCF_03340 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
MKBDJGCF_03341 1.06e-288 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MKBDJGCF_03342 8.38e-297 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MKBDJGCF_03344 3.42e-197 yitS - - S - - - protein conserved in bacteria
MKBDJGCF_03345 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_03346 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
MKBDJGCF_03347 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
MKBDJGCF_03348 1.49e-11 - - - - - - - -
MKBDJGCF_03349 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MKBDJGCF_03350 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MKBDJGCF_03351 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MKBDJGCF_03352 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MKBDJGCF_03353 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MKBDJGCF_03354 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
MKBDJGCF_03355 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKBDJGCF_03356 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKBDJGCF_03357 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MKBDJGCF_03358 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MKBDJGCF_03359 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MKBDJGCF_03360 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MKBDJGCF_03361 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKBDJGCF_03362 2.07e-38 yjzC - - S - - - YjzC-like protein
MKBDJGCF_03363 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
MKBDJGCF_03364 1.09e-169 yjaU - - I - - - carboxylic ester hydrolase activity
MKBDJGCF_03365 7.04e-127 yjaV - - - - - - -
MKBDJGCF_03366 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MKBDJGCF_03367 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MKBDJGCF_03368 1.46e-37 yjzB - - - - - - -
MKBDJGCF_03369 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKBDJGCF_03370 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKBDJGCF_03371 4.99e-179 yjaZ - - O - - - Zn-dependent protease
MKBDJGCF_03372 4.64e-229 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03373 1.1e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03374 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MKBDJGCF_03375 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_03376 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_03377 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
MKBDJGCF_03378 3.56e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MKBDJGCF_03379 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MKBDJGCF_03380 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_03381 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKBDJGCF_03382 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03383 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03384 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
MKBDJGCF_03385 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKBDJGCF_03386 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKBDJGCF_03387 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
MKBDJGCF_03388 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKBDJGCF_03389 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
MKBDJGCF_03390 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MKBDJGCF_03391 3.14e-27 - - - - - - - -
MKBDJGCF_03392 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MKBDJGCF_03393 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MKBDJGCF_03394 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKBDJGCF_03395 8.1e-118 yjbK - - S - - - protein conserved in bacteria
MKBDJGCF_03396 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
MKBDJGCF_03397 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MKBDJGCF_03398 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKBDJGCF_03399 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MKBDJGCF_03400 5.22e-175 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MKBDJGCF_03401 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKBDJGCF_03402 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKBDJGCF_03403 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MKBDJGCF_03404 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MKBDJGCF_03405 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
MKBDJGCF_03406 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKBDJGCF_03407 7.09e-228 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKBDJGCF_03408 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MKBDJGCF_03409 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MKBDJGCF_03410 2.47e-100 yjbX - - S - - - Spore coat protein
MKBDJGCF_03411 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MKBDJGCF_03412 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MKBDJGCF_03413 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MKBDJGCF_03414 1.02e-36 cotW - - - ko:K06341 - ko00000 -
MKBDJGCF_03415 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MKBDJGCF_03416 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
MKBDJGCF_03419 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MKBDJGCF_03420 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
MKBDJGCF_03421 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MKBDJGCF_03422 1.62e-44 - - - - - - - -
MKBDJGCF_03423 6.27e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MKBDJGCF_03424 3.3e-134 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MKBDJGCF_03425 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MKBDJGCF_03426 1.19e-45 - - - K - - - SpoVT / AbrB like domain
MKBDJGCF_03427 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKBDJGCF_03428 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MKBDJGCF_03429 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MKBDJGCF_03430 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MKBDJGCF_03431 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MKBDJGCF_03433 2.89e-73 - - - - - - - -
MKBDJGCF_03434 2.31e-90 - - - S - - - Bacterial EndoU nuclease
MKBDJGCF_03435 1.06e-42 - - - - - - - -
MKBDJGCF_03436 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
MKBDJGCF_03437 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
MKBDJGCF_03438 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
MKBDJGCF_03439 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
MKBDJGCF_03441 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
MKBDJGCF_03442 0.0 - - - K - - - Psort location Cytoplasmic, score
MKBDJGCF_03443 9.18e-49 - - - S - - - YolD-like protein
MKBDJGCF_03444 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKBDJGCF_03445 3.58e-16 - - - S - - - Bacillus cereus group antimicrobial protein
MKBDJGCF_03449 6.15e-32 - - - N - - - Kelch motif
MKBDJGCF_03451 1.32e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MKBDJGCF_03452 5.19e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MKBDJGCF_03453 1.35e-302 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MKBDJGCF_03454 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_03455 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MKBDJGCF_03456 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKBDJGCF_03457 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_03458 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MKBDJGCF_03459 1.14e-176 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MKBDJGCF_03460 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
MKBDJGCF_03461 3.81e-45 - - - - - - - -
MKBDJGCF_03462 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MKBDJGCF_03463 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MKBDJGCF_03465 1.07e-28 yjfB - - S - - - Putative motility protein
MKBDJGCF_03466 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
MKBDJGCF_03467 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
MKBDJGCF_03468 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MKBDJGCF_03469 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
MKBDJGCF_03470 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MKBDJGCF_03471 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKBDJGCF_03472 1.73e-40 - - - - - - - -
MKBDJGCF_03473 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MKBDJGCF_03474 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MKBDJGCF_03475 2.23e-159 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
MKBDJGCF_03476 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MKBDJGCF_03477 1.47e-110 yjlB - - S - - - Cupin domain
MKBDJGCF_03478 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MKBDJGCF_03479 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MKBDJGCF_03480 1.75e-98 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MKBDJGCF_03481 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MKBDJGCF_03482 2.6e-202 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MKBDJGCF_03483 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
MKBDJGCF_03484 1.84e-166 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKBDJGCF_03486 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MKBDJGCF_03487 9.4e-100 yjoA - - S - - - DinB family
MKBDJGCF_03488 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MKBDJGCF_03490 5.72e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MKBDJGCF_03491 3.19e-79 yjqA - - S - - - Bacterial PH domain
MKBDJGCF_03492 2.69e-128 yjqB - - S - - - phage-related replication protein
MKBDJGCF_03493 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
MKBDJGCF_03494 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_03496 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
MKBDJGCF_03500 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKBDJGCF_03501 3.6e-137 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MKBDJGCF_03502 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MKBDJGCF_03503 1.72e-302 xkdE3 - - S - - - portal protein
MKBDJGCF_03504 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
MKBDJGCF_03505 3.38e-202 xkdG - - S - - - Phage capsid family
MKBDJGCF_03506 8.84e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
MKBDJGCF_03508 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MKBDJGCF_03509 1.82e-75 xkdJ - - - - - - -
MKBDJGCF_03510 3.86e-21 - - - - - - - -
MKBDJGCF_03511 4.44e-285 xkdK - - S - - - Phage tail sheath C-terminal domain
MKBDJGCF_03512 8.21e-97 xkdM - - S - - - Phage tail tube protein
MKBDJGCF_03513 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MKBDJGCF_03514 4.33e-27 - - - - - - - -
MKBDJGCF_03515 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKBDJGCF_03516 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKBDJGCF_03517 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
MKBDJGCF_03518 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKBDJGCF_03519 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MKBDJGCF_03520 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKBDJGCF_03521 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKBDJGCF_03522 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKBDJGCF_03523 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKBDJGCF_03524 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MKBDJGCF_03525 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKBDJGCF_03526 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKBDJGCF_03527 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MKBDJGCF_03528 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MKBDJGCF_03529 2.38e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MKBDJGCF_03530 6.79e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MKBDJGCF_03531 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
MKBDJGCF_03532 2.63e-74 yhhY - - K - - - FR47-like protein
MKBDJGCF_03533 3.84e-215 yyaD - - S - - - Membrane
MKBDJGCF_03534 1.82e-45 yyzM - - S - - - protein conserved in bacteria
MKBDJGCF_03535 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKBDJGCF_03536 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKBDJGCF_03537 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MKBDJGCF_03538 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKBDJGCF_03539 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKBDJGCF_03540 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MKBDJGCF_03541 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKBDJGCF_03542 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MKBDJGCF_03543 7.31e-218 ccpB - - K - - - Transcriptional regulator
MKBDJGCF_03544 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_03545 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MKBDJGCF_03546 1.66e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKBDJGCF_03547 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MKBDJGCF_03548 4.35e-208 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MKBDJGCF_03549 1.25e-88 ynaF - - - - - - -
MKBDJGCF_03550 8.63e-130 - - - S - - - Alpha/beta hydrolase family
MKBDJGCF_03551 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MKBDJGCF_03552 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
MKBDJGCF_03553 7.24e-97 yybA - - K - - - transcriptional
MKBDJGCF_03554 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MKBDJGCF_03555 2.55e-85 - - - K - - - Winged helix DNA-binding domain
MKBDJGCF_03556 1.56e-144 ydgI - - C - - - nitroreductase
MKBDJGCF_03557 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MKBDJGCF_03558 3.23e-183 - - - G - - - Major Facilitator Superfamily
MKBDJGCF_03559 3.74e-115 - - - S - - - PFAM DinB family protein
MKBDJGCF_03560 7.61e-142 - - - K - - - FCD domain
MKBDJGCF_03561 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MKBDJGCF_03562 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MKBDJGCF_03563 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKBDJGCF_03564 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MKBDJGCF_03565 2.54e-84 yybR - - K - - - Transcriptional regulator
MKBDJGCF_03566 9.65e-105 cotF - - M ko:K06329 - ko00000 Spore coat protein
MKBDJGCF_03568 6.36e-191 yybS - - S - - - membrane
MKBDJGCF_03569 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MKBDJGCF_03570 1.85e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MKBDJGCF_03571 1.92e-106 - - - KLT - - - COG0515 Serine threonine protein kinase
MKBDJGCF_03572 3.43e-154 - - - S - - - GlcNAc-PI de-N-acetylase
MKBDJGCF_03573 1.6e-278 - - - M - - - Glycosyltransferase Family 4
MKBDJGCF_03574 7.36e-294 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
MKBDJGCF_03575 5.54e-244 - - - S - - - Ecdysteroid kinase
MKBDJGCF_03576 3.86e-271 - - - M - - - Glycosyltransferase Family 4
MKBDJGCF_03577 3.6e-25 yycC - - K - - - YycC-like protein
MKBDJGCF_03579 9e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MKBDJGCF_03580 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MKBDJGCF_03581 1.57e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKBDJGCF_03582 1.83e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKBDJGCF_03587 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKBDJGCF_03588 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MKBDJGCF_03589 0.0 yycH - - S - - - protein conserved in bacteria
MKBDJGCF_03590 1.1e-191 yycI - - S - - - protein conserved in bacteria
MKBDJGCF_03591 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MKBDJGCF_03592 1.6e-269 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKBDJGCF_03593 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
MKBDJGCF_03594 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
MKBDJGCF_03595 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MKBDJGCF_03596 8.24e-255 - - - S - - - Major Facilitator Superfamily
MKBDJGCF_03597 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MKBDJGCF_03598 3.82e-57 sdpR - - K - - - transcriptional
MKBDJGCF_03599 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MKBDJGCF_03600 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MKBDJGCF_03601 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MKBDJGCF_03602 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MKBDJGCF_03603 2.05e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MKBDJGCF_03605 2.13e-106 yycN - - K - - - Acetyltransferase
MKBDJGCF_03606 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MKBDJGCF_03607 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKBDJGCF_03608 5.96e-264 yycP - - - - - - -
MKBDJGCF_03612 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKBDJGCF_03613 0.0 - - - L - - - AAA ATPase domain
MKBDJGCF_03614 0.0 - - - L - - - AAA domain
MKBDJGCF_03615 6.58e-27 - - - - - - - -
MKBDJGCF_03616 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
MKBDJGCF_03617 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKBDJGCF_03618 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MKBDJGCF_03619 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MKBDJGCF_03620 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MKBDJGCF_03621 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MKBDJGCF_03622 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MKBDJGCF_03623 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MKBDJGCF_03624 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKBDJGCF_03625 9.99e-39 yazB - - K - - - transcriptional
MKBDJGCF_03626 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKBDJGCF_03627 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKBDJGCF_03628 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKBDJGCF_03629 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MKBDJGCF_03630 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MKBDJGCF_03631 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKBDJGCF_03632 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MKBDJGCF_03633 4.24e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MKBDJGCF_03634 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKBDJGCF_03635 5.46e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKBDJGCF_03636 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKBDJGCF_03637 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MKBDJGCF_03638 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKBDJGCF_03639 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MKBDJGCF_03640 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MKBDJGCF_03641 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MKBDJGCF_03644 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MKBDJGCF_03645 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MKBDJGCF_03646 5.13e-129 yabQ - - S - - - spore cortex biosynthesis protein
MKBDJGCF_03647 5.47e-66 yabP - - S - - - Sporulation protein YabP
MKBDJGCF_03648 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MKBDJGCF_03649 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MKBDJGCF_03650 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKBDJGCF_03651 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MKBDJGCF_03652 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKBDJGCF_03653 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
MKBDJGCF_03654 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKBDJGCF_03655 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKBDJGCF_03656 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKBDJGCF_03657 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKBDJGCF_03658 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MKBDJGCF_03659 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MKBDJGCF_03660 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MKBDJGCF_03661 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKBDJGCF_03662 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
MKBDJGCF_03663 5.32e-53 veg - - S - - - protein conserved in bacteria
MKBDJGCF_03664 1.2e-185 yabG - - S ko:K06436 - ko00000 peptidase
MKBDJGCF_03665 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKBDJGCF_03666 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKBDJGCF_03667 3.55e-288 yabE - - T - - - protein conserved in bacteria
MKBDJGCF_03668 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MKBDJGCF_03669 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKBDJGCF_03670 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MKBDJGCF_03671 8.06e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKBDJGCF_03672 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MKBDJGCF_03673 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MKBDJGCF_03674 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
MKBDJGCF_03675 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MKBDJGCF_03676 5.75e-224 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MKBDJGCF_03677 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MKBDJGCF_03678 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
MKBDJGCF_03679 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKBDJGCF_03680 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MKBDJGCF_03681 6.32e-226 yaaN - - P - - - Belongs to the TelA family
MKBDJGCF_03682 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKBDJGCF_03683 1.5e-40 csfB - - S - - - Inhibitor of sigma-G Gin
MKBDJGCF_03684 3.37e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
MKBDJGCF_03685 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
MKBDJGCF_03689 3.27e-110 - - - - - - - -
MKBDJGCF_03690 1.67e-76 - - - S - - - DNA binding
MKBDJGCF_03691 1.18e-48 - - - - - - - -
MKBDJGCF_03692 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_03693 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_03694 8.41e-82 - - - - - - - -
MKBDJGCF_03695 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
MKBDJGCF_03696 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
MKBDJGCF_03697 1.16e-43 - - - L - - - Arm DNA-binding domain
MKBDJGCF_03698 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKBDJGCF_03699 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKBDJGCF_03700 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MKBDJGCF_03701 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MKBDJGCF_03702 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKBDJGCF_03703 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKBDJGCF_03704 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKBDJGCF_03705 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MKBDJGCF_03706 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MKBDJGCF_03707 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKBDJGCF_03708 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKBDJGCF_03709 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MKBDJGCF_03710 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MKBDJGCF_03711 4.4e-221 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKBDJGCF_03714 5.51e-62 xkdA - - E - - - IrrE N-terminal-like domain
MKBDJGCF_03715 4.58e-98 - - - S - - - Bacterial PH domain
MKBDJGCF_03716 1.26e-131 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MKBDJGCF_03717 4.47e-35 - - - K ko:K07467 - ko00000 sequence-specific DNA binding
MKBDJGCF_03718 9.21e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
MKBDJGCF_03723 1.89e-41 - - - K - - - Phage regulatory protein Rha (Phage_pRha)
MKBDJGCF_03724 4.13e-97 - - - - - - - -
MKBDJGCF_03729 2.3e-194 yqaJ - - L - - - YqaJ-like viral recombinase domain
MKBDJGCF_03731 2.94e-78 recT - - L ko:K07455 - ko00000,ko03400 RecT family
MKBDJGCF_03732 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
MKBDJGCF_03733 1.1e-73 ygzB - - S - - - UPF0295 protein
MKBDJGCF_03734 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MKBDJGCF_03735 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MKBDJGCF_03736 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MKBDJGCF_03737 1.76e-237 ygaE - - S - - - Membrane
MKBDJGCF_03738 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MKBDJGCF_03739 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MKBDJGCF_03740 5.69e-49 ygaB - - S - - - YgaB-like protein
MKBDJGCF_03741 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MKBDJGCF_03742 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKBDJGCF_03743 1.47e-49 yfhS - - - - - - -
MKBDJGCF_03744 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MKBDJGCF_03745 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MKBDJGCF_03746 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MKBDJGCF_03747 4.51e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MKBDJGCF_03748 6.02e-213 - - - S - - - Alpha/beta hydrolase family
MKBDJGCF_03749 2.82e-48 yfhL - - S - - - SdpI/YhfL protein family
MKBDJGCF_03750 1.14e-112 yfhK - - T - - - Bacterial SH3 domain homologues
MKBDJGCF_03751 1.49e-58 yfhJ - - S - - - WVELL protein
MKBDJGCF_03752 1.4e-206 mpr - - M - - - Belongs to the peptidase S1B family
MKBDJGCF_03754 4.06e-147 yfhI - - EGP - - - -transporter
MKBDJGCF_03755 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
MKBDJGCF_03756 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MKBDJGCF_03757 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MKBDJGCF_03759 6.01e-33 yfhD - - S - - - YfhD-like protein
MKBDJGCF_03760 3.09e-133 yfhC - - C - - - nitroreductase
MKBDJGCF_03761 1.27e-193 yfhB - - S - - - PhzF family
MKBDJGCF_03762 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKBDJGCF_03763 1.48e-103 yfiV - - K - - - transcriptional
MKBDJGCF_03764 0.0 yfiU - - EGP - - - the major facilitator superfamily
MKBDJGCF_03765 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MKBDJGCF_03766 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MKBDJGCF_03767 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MKBDJGCF_03768 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MKBDJGCF_03769 1e-119 padR - - K - - - transcriptional
MKBDJGCF_03770 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKBDJGCF_03771 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKBDJGCF_03772 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MKBDJGCF_03773 7.86e-82 yfiD3 - - S - - - DoxX
MKBDJGCF_03774 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MKBDJGCF_03775 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MKBDJGCF_03776 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
MKBDJGCF_03777 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MKBDJGCF_03778 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MKBDJGCF_03779 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKBDJGCF_03780 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MKBDJGCF_03781 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MKBDJGCF_03782 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKBDJGCF_03783 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKBDJGCF_03784 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKBDJGCF_03785 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKBDJGCF_03786 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
MKBDJGCF_03787 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKBDJGCF_03788 1.83e-60 - - - S - - - YfzA-like protein
MKBDJGCF_03791 1.6e-200 - - - L - - - Recombinase
MKBDJGCF_03792 7.33e-09 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKBDJGCF_03795 2.46e-31 - - - S - - - STAS-like domain of unknown function (DUF4325)
MKBDJGCF_03796 1.4e-111 - - - T - - - Histidine kinase-like ATPases
MKBDJGCF_03797 4.75e-38 - - - K - - - Helix-turn-helix domain
MKBDJGCF_03799 7.74e-86 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_03800 2.07e-37 xhlB - - S - - - SPP1 phage holin
MKBDJGCF_03801 1.98e-39 xhlA - - S - - - Haemolysin XhlA
MKBDJGCF_03802 1.4e-25 xkdX - - - - - - -
MKBDJGCF_03804 5.64e-60 - - - - - - - -
MKBDJGCF_03805 4.28e-79 - - - - - - - -
MKBDJGCF_03806 7.91e-127 - - - S - - - homolog of phage Mu protein gp47
MKBDJGCF_03807 2.39e-32 - - - S - - - Protein of unknown function (DUF2634)
MKBDJGCF_03808 3.21e-35 - - - - - - - -
MKBDJGCF_03809 3.57e-109 - - - - - - - -
MKBDJGCF_03810 5.45e-31 - - - - - - - -
MKBDJGCF_03811 9.44e-55 - - - M - - - LysM domain
MKBDJGCF_03812 4e-181 - - - N - - - phage tail tape measure protein
MKBDJGCF_03813 1.16e-19 - - - - - - - -
MKBDJGCF_03814 2.25e-46 - - - - - - - -
MKBDJGCF_03815 8.83e-131 - - - S - - - Protein of unknown function (DUF3383)
MKBDJGCF_03816 5.17e-42 - - - - - - - -
MKBDJGCF_03818 3.47e-61 - - - - - - - -
MKBDJGCF_03820 2.65e-39 - - - S - - - Phage Mu protein F like protein
MKBDJGCF_03822 8.89e-154 - - - S - - - P22 coat protein - gene protein 5
MKBDJGCF_03823 4.94e-71 - - - S - - - Domain of unknown function (DUF4355)
MKBDJGCF_03825 1.75e-193 - - - S - - - Phage portal protein, SPP1 Gp6-like
MKBDJGCF_03826 1.57e-229 - - - S - - - Terminase-like family
MKBDJGCF_03827 3.1e-52 yqaS - - L - - - DNA packaging
MKBDJGCF_03828 1.64e-224 yaaC - - S - - - YaaC-like Protein
MKBDJGCF_03829 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKBDJGCF_03830 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MKBDJGCF_03831 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKBDJGCF_03832 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKBDJGCF_03833 4.16e-281 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKBDJGCF_03834 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MKBDJGCF_03836 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MKBDJGCF_03837 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MKBDJGCF_03838 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MKBDJGCF_03839 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MKBDJGCF_03840 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKBDJGCF_03841 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKBDJGCF_03842 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKBDJGCF_03843 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKBDJGCF_03844 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
MKBDJGCF_03845 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MKBDJGCF_03846 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MKBDJGCF_03847 2.05e-170 yqaM - - L - - - IstB-like ATP binding protein
MKBDJGCF_03849 5.4e-17 - - - S - - - YopX protein
MKBDJGCF_03850 5.48e-72 - - - S - - - Protein of unknown function (DUF1064)
MKBDJGCF_03852 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
MKBDJGCF_03855 5.46e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MKBDJGCF_03856 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
MKBDJGCF_03857 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MKBDJGCF_03858 1.95e-102 gerD - - - ko:K06294 - ko00000 -
MKBDJGCF_03859 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKBDJGCF_03860 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MKBDJGCF_03861 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
MKBDJGCF_03862 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
MKBDJGCF_03863 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MKBDJGCF_03864 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKBDJGCF_03865 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKBDJGCF_03866 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKBDJGCF_03867 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKBDJGCF_03868 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKBDJGCF_03869 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MKBDJGCF_03870 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKBDJGCF_03871 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKBDJGCF_03872 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKBDJGCF_03873 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MKBDJGCF_03874 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKBDJGCF_03875 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MKBDJGCF_03876 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKBDJGCF_03877 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKBDJGCF_03878 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MKBDJGCF_03879 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MKBDJGCF_03880 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKBDJGCF_03881 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKBDJGCF_03882 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKBDJGCF_03883 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKBDJGCF_03884 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKBDJGCF_03885 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKBDJGCF_03886 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKBDJGCF_03887 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKBDJGCF_03888 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKBDJGCF_03889 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MKBDJGCF_03890 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKBDJGCF_03891 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKBDJGCF_03892 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKBDJGCF_03893 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKBDJGCF_03894 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKBDJGCF_03895 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKBDJGCF_03896 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MKBDJGCF_03897 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKBDJGCF_03898 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MKBDJGCF_03899 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
MKBDJGCF_03900 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKBDJGCF_03901 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKBDJGCF_03902 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKBDJGCF_03903 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKBDJGCF_03904 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MKBDJGCF_03905 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKBDJGCF_03906 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKBDJGCF_03907 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MKBDJGCF_03908 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKBDJGCF_03909 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKBDJGCF_03910 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKBDJGCF_03911 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKBDJGCF_03912 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MKBDJGCF_03913 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKBDJGCF_03914 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MKBDJGCF_03915 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MKBDJGCF_03916 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKBDJGCF_03917 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKBDJGCF_03918 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MKBDJGCF_03919 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MKBDJGCF_03920 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKBDJGCF_03921 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKBDJGCF_03922 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKBDJGCF_03923 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MKBDJGCF_03924 3.64e-249 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKBDJGCF_03925 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKBDJGCF_03926 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MKBDJGCF_03927 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MKBDJGCF_03928 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MKBDJGCF_03929 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MKBDJGCF_03946 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)