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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOEIEHHP_00001	4.36e-284	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOEIEHHP_00002	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_00003	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_00004	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IOEIEHHP_00006	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IOEIEHHP_00007	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IOEIEHHP_00008	1.96e-126	-	-	-	-	-	-	-	-
IOEIEHHP_00009	1.69e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOEIEHHP_00010	6e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
IOEIEHHP_00011	1.42e-132	-	-	-	-	-	-	-	-
IOEIEHHP_00012	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOEIEHHP_00013	3.08e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOEIEHHP_00014	2.08e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOEIEHHP_00015	5.79e-85	-	-	-	-	-	-	-	-
IOEIEHHP_00016	1.37e-90	-	-	-	-	-	-	-	-
IOEIEHHP_00017	4.44e-62	-	-	-	-	-	-	-	-
IOEIEHHP_00018	2.83e-202	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOEIEHHP_00019	6.87e-162	citR	-	-	K	-	-	-	FCD
IOEIEHHP_00020	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
IOEIEHHP_00021	1.97e-130	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IOEIEHHP_00022	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IOEIEHHP_00023	2.5e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
IOEIEHHP_00024	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
IOEIEHHP_00025	2.88e-226	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOEIEHHP_00026	6.58e-07	-	-	-	-	-	-	-	-
IOEIEHHP_00027	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
IOEIEHHP_00028	7.15e-58	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
IOEIEHHP_00029	1.11e-66	-	-	-	-	-	-	-	-
IOEIEHHP_00030	2.47e-308	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
IOEIEHHP_00031	4.38e-56	-	-	-	-	-	-	-	-
IOEIEHHP_00032	1.56e-127	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IOEIEHHP_00033	2.85e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_00034	2.23e-136	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IOEIEHHP_00035	7.63e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOEIEHHP_00036	4.82e-83	ORF00048	-	-	-	-	-	-	-
IOEIEHHP_00037	2.28e-170	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IOEIEHHP_00038	3.44e-208	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00039	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
IOEIEHHP_00040	6.93e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IOEIEHHP_00041	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_00042	2.1e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOEIEHHP_00043	2.51e-236	-	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00044	1.65e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
IOEIEHHP_00045	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IOEIEHHP_00046	3.66e-165	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00047	4.85e-16	-	-	-	-	-	-	-	-
IOEIEHHP_00048	2.23e-204	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOEIEHHP_00049	4.8e-251	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOEIEHHP_00050	5.22e-65	-	-	-	-	-	-	-	-
IOEIEHHP_00051	3.34e-217	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOEIEHHP_00052	4.34e-212	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00053	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOEIEHHP_00054	2.35e-06	-	-	-	-	-	-	-	-
IOEIEHHP_00055	2.72e-51	-	-	-	-	-	-	-	-
IOEIEHHP_00056	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_00057	6.18e-11	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_00058	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
IOEIEHHP_00059	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOEIEHHP_00060	1.3e-144	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
IOEIEHHP_00061	8.3e-10	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
IOEIEHHP_00062	1.05e-155	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
IOEIEHHP_00063	2.21e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00065	1.16e-11	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
IOEIEHHP_00066	3.97e-49	-	-	-	-	-	-	-	-
IOEIEHHP_00067	4.25e-34	-	-	-	-	-	-	-	-
IOEIEHHP_00068	5.94e-21	-	-	-	-	-	-	-	-
IOEIEHHP_00069	2.65e-06	-	-	-	S	-	-	-	Phage minor structural protein GP20
IOEIEHHP_00071	1.12e-84	-	-	-	S	-	-	-	Phage minor capsid protein 2
IOEIEHHP_00072	5.57e-110	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IOEIEHHP_00073	2.53e-158	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
IOEIEHHP_00074	3.37e-11	-	-	-	L	ko:K07474	-	ko00000	DNA packaging
IOEIEHHP_00075	1.36e-13	-	-	-	-	-	-	-	-
IOEIEHHP_00078	2.71e-33	-	-	-	-	-	-	-	-
IOEIEHHP_00080	1.13e-22	-	-	-	-	-	-	-	-
IOEIEHHP_00081	1.59e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IOEIEHHP_00086	1.51e-07	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IOEIEHHP_00089	8.8e-125	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
IOEIEHHP_00091	2.77e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOEIEHHP_00092	4.69e-86	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
IOEIEHHP_00094	2.62e-105	-	-	-	L	-	-	-	DnaD domain protein
IOEIEHHP_00095	2.21e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
IOEIEHHP_00096	3.15e-68	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
IOEIEHHP_00097	8.34e-28	-	-	-	-	-	-	-	-
IOEIEHHP_00098	9.58e-60	-	-	-	-	-	-	-	-
IOEIEHHP_00099	3.74e-37	-	-	-	D	-	-	-	nuclear chromosome segregation
IOEIEHHP_00100	3.18e-69	-	-	-	D	-	-	-	nuclear chromosome segregation
IOEIEHHP_00103	1.71e-26	-	-	-	-	-	-	-	-
IOEIEHHP_00105	1.07e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00106	2.01e-59	-	-	-	E	-	-	-	Zn peptidase
IOEIEHHP_00107	2.77e-13	-	-	-	S	-	-	-	Short C-terminal domain
IOEIEHHP_00108	5.37e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOEIEHHP_00109	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOEIEHHP_00110	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IOEIEHHP_00111	1.02e-64	-	-	-	-	-	-	-	-
IOEIEHHP_00112	5.88e-52	-	-	-	-	-	-	-	-
IOEIEHHP_00113	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOEIEHHP_00114	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IOEIEHHP_00115	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOEIEHHP_00116	1.82e-37	-	-	-	-	-	-	-	-
IOEIEHHP_00117	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IOEIEHHP_00118	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOEIEHHP_00119	8.4e-95	yjhE	-	-	S	-	-	-	Phage tail protein
IOEIEHHP_00120	1.08e-303	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOEIEHHP_00121	1.07e-236	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IOEIEHHP_00122	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IOEIEHHP_00123	5.9e-219	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IOEIEHHP_00124	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOEIEHHP_00125	3.26e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00126	0.0	-	-	-	E	-	-	-	Amino Acid
IOEIEHHP_00127	2.64e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOEIEHHP_00128	6.21e-302	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOEIEHHP_00129	4.99e-195	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
IOEIEHHP_00130	1.38e-125	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOEIEHHP_00131	9.92e-143	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOEIEHHP_00132	4.22e-127	-	-	-	M	-	-	-	Peptidase_C39 like family
IOEIEHHP_00133	7.43e-05	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOEIEHHP_00134	8.06e-253	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
IOEIEHHP_00135	2.39e-255	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IOEIEHHP_00136	5.87e-172	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_00137	1.07e-209	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOEIEHHP_00138	5.19e-148	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00139	9.72e-156	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00140	3.15e-174	-	-	-	-	-	-	-	-
IOEIEHHP_00143	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
IOEIEHHP_00144	1.02e-188	-	-	-	M	-	-	-	hydrolase, family 25
IOEIEHHP_00145	1.17e-35	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOEIEHHP_00146	6.48e-115	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_00147	3.29e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00148	2.12e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00149	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
IOEIEHHP_00150	1.58e-195	-	-	-	S	-	-	-	hydrolase
IOEIEHHP_00151	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
IOEIEHHP_00152	9.06e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IOEIEHHP_00160	4.66e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOEIEHHP_00161	2.28e-250	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IOEIEHHP_00162	1.01e-224	-	-	-	-	-	-	-	-
IOEIEHHP_00163	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IOEIEHHP_00164	1.61e-24	-	-	-	-	-	-	-	-
IOEIEHHP_00165	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_00166	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00167	7.03e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
IOEIEHHP_00168	1.47e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
IOEIEHHP_00169	2.13e-101	-	-	-	O	-	-	-	OsmC-like protein
IOEIEHHP_00170	1.28e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00171	6.45e-265	-	-	-	-	-	-	-	-
IOEIEHHP_00173	7.65e-187	-	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00175	0.0	-	-	-	L	-	-	-	Exonuclease
IOEIEHHP_00176	3.53e-08	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
IOEIEHHP_00177	1.38e-41	-	-	-	L	-	-	-	RelB antitoxin
IOEIEHHP_00178	2.1e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00179	5.46e-260	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
IOEIEHHP_00180	1.2e-176	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00181	3.32e-155	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOEIEHHP_00182	8.35e-77	ydfF	-	-	K	-	-	-	Transcriptional
IOEIEHHP_00183	1.54e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IOEIEHHP_00184	3.42e-45	-	-	-	-	-	-	-	-
IOEIEHHP_00185	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IOEIEHHP_00186	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOEIEHHP_00187	1.01e-61	-	-	-	-	-	-	-	-
IOEIEHHP_00188	1.02e-187	pbpE	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_00189	1.31e-244	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOEIEHHP_00190	5.64e-172	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
IOEIEHHP_00191	2.49e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IOEIEHHP_00192	2.55e-35	-	-	-	S	-	-	-	Belongs to the UPF0342 family
IOEIEHHP_00193	7.49e-121	-	-	-	S	-	-	-	Glucosyl transferase GtrII
IOEIEHHP_00194	2.55e-58	-	-	-	-	-	-	-	-
IOEIEHHP_00195	8.03e-183	-	-	-	-	-	-	-	-
IOEIEHHP_00196	7.95e-154	-	-	-	M	-	-	-	Peptidase_C39 like family
IOEIEHHP_00197	3.74e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOEIEHHP_00198	1.97e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOEIEHHP_00199	2.2e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IOEIEHHP_00200	1.53e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOEIEHHP_00201	3.24e-220	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOEIEHHP_00202	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
IOEIEHHP_00203	1.61e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
IOEIEHHP_00204	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00205	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00206	4.13e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOEIEHHP_00208	8.66e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00209	4.58e-220	-	-	-	-	-	-	-	-
IOEIEHHP_00210	0.000417	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IOEIEHHP_00211	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOEIEHHP_00212	1.1e-13	-	-	-	-	-	-	-	-
IOEIEHHP_00213	5.13e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IOEIEHHP_00214	1.12e-86	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_00215	1.34e-199	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IOEIEHHP_00216	5.36e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOEIEHHP_00217	5.22e-207	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOEIEHHP_00218	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOEIEHHP_00219	1.27e-221	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOEIEHHP_00220	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOEIEHHP_00221	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOEIEHHP_00222	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOEIEHHP_00223	6.1e-258	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IOEIEHHP_00224	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOEIEHHP_00225	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOEIEHHP_00226	1.02e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOEIEHHP_00227	1.38e-161	-	-	-	M	-	-	-	Sortase family
IOEIEHHP_00228	1.28e-163	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOEIEHHP_00229	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
IOEIEHHP_00230	3.92e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
IOEIEHHP_00231	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
IOEIEHHP_00232	2.22e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IOEIEHHP_00233	2.24e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_00237	3.87e-58	-	-	-	-	-	-	-	-
IOEIEHHP_00238	3.67e-97	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
IOEIEHHP_00239	8.14e-62	-	-	-	-	-	-	-	-
IOEIEHHP_00241	2e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
IOEIEHHP_00242	1.91e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IOEIEHHP_00243	3.52e-177	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IOEIEHHP_00244	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IOEIEHHP_00245	3.64e-119	-	-	-	S	-	-	-	VanZ like family
IOEIEHHP_00246	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
IOEIEHHP_00247	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOEIEHHP_00248	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOEIEHHP_00249	2.95e-215	ybbR	-	-	S	-	-	-	YbbR-like protein
IOEIEHHP_00250	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOEIEHHP_00251	3.36e-164	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOEIEHHP_00252	6.18e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00253	9.33e-153	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_00254	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IOEIEHHP_00256	1.37e-78	-	-	-	-	-	-	-	-
IOEIEHHP_00257	2.9e-111	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IOEIEHHP_00258	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_00259	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00260	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00261	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOEIEHHP_00262	4.84e-125	-	-	-	K	-	-	-	Cupin domain
IOEIEHHP_00263	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IOEIEHHP_00264	8.79e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IOEIEHHP_00265	3.32e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IOEIEHHP_00266	1.62e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOEIEHHP_00267	1.88e-274	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOEIEHHP_00268	5.97e-210	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00269	5.07e-108	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IOEIEHHP_00270	6.35e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IOEIEHHP_00271	5.47e-167	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOEIEHHP_00272	4.87e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOEIEHHP_00273	5.33e-119	-	-	-	-	-	-	-	-
IOEIEHHP_00274	1.6e-133	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
IOEIEHHP_00275	1.73e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00276	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
IOEIEHHP_00277	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00278	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOEIEHHP_00279	4.21e-305	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
IOEIEHHP_00280	7.78e-66	-	-	-	-	-	-	-	-
IOEIEHHP_00281	5.6e-148	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOEIEHHP_00282	1.57e-112	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IOEIEHHP_00283	2.96e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOEIEHHP_00284	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOEIEHHP_00285	1.7e-96	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOEIEHHP_00286	1.54e-271	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOEIEHHP_00287	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOEIEHHP_00288	9.46e-184	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOEIEHHP_00289	4.99e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
IOEIEHHP_00290	6.48e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_00291	6.94e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IOEIEHHP_00292	1.53e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOEIEHHP_00293	7.89e-304	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_00294	9.43e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOEIEHHP_00295	2.28e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOEIEHHP_00296	1.05e-164	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IOEIEHHP_00297	6.25e-217	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IOEIEHHP_00298	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IOEIEHHP_00299	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
IOEIEHHP_00300	1.03e-185	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOEIEHHP_00301	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_00302	5.77e-295	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_00303	2.71e-198	-	-	-	-	-	-	-	-
IOEIEHHP_00304	3.26e-153	-	-	-	-	-	-	-	-
IOEIEHHP_00305	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
IOEIEHHP_00306	3.9e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOEIEHHP_00307	1.74e-111	-	-	-	-	-	-	-	-
IOEIEHHP_00308	2.76e-248	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOEIEHHP_00309	1.33e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IOEIEHHP_00310	1.91e-279	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
IOEIEHHP_00311	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOEIEHHP_00312	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
IOEIEHHP_00313	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00314	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00315	1.23e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00316	3.18e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00317	1.13e-221	lacC	2.7.1.144	-	F	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_00318	1.69e-189	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	KR domain
IOEIEHHP_00319	1.74e-308	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00320	1.7e-112	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00321	8.14e-63	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00322	6.21e-208	-	-	-	-	-	-	-	-
IOEIEHHP_00324	3.16e-166	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOEIEHHP_00325	2.17e-80	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
IOEIEHHP_00326	8.19e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00327	0.0	-	-	-	GK	-	-	-	helix_turn_helix, arabinose operon control protein
IOEIEHHP_00328	3.34e-209	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOEIEHHP_00329	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IOEIEHHP_00330	0.0	-	-	-	E	-	-	-	Amino Acid
IOEIEHHP_00331	0.0	ebgA	3.2.1.23	-	G	ko:K01190,ko:K12111	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IOEIEHHP_00332	5.62e-126	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IOEIEHHP_00333	3.84e-311	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
IOEIEHHP_00334	2.97e-286	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00335	1.22e-271	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOEIEHHP_00337	8.04e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IOEIEHHP_00338	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
IOEIEHHP_00339	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IOEIEHHP_00340	4.54e-204	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IOEIEHHP_00341	1.16e-304	-	-	-	G	-	-	-	Metalloenzyme superfamily
IOEIEHHP_00342	6.68e-283	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
IOEIEHHP_00343	2.17e-264	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
IOEIEHHP_00344	6.49e-212	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
IOEIEHHP_00345	1.17e-274	-	-	-	S	-	-	-	Protein of unknown function
IOEIEHHP_00346	1.01e-75	-	-	-	S	-	-	-	Protein of unknown function DUF2620
IOEIEHHP_00348	1.37e-218	-	-	-	P	-	-	-	YhfZ C-terminal domain
IOEIEHHP_00349	2.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOEIEHHP_00350	1.74e-162	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
IOEIEHHP_00351	8.2e-163	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
IOEIEHHP_00352	1.74e-131	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
IOEIEHHP_00353	4.01e-99	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOEIEHHP_00354	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
IOEIEHHP_00355	2.4e-280	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IOEIEHHP_00356	9.22e-317	-	-	-	E	-	-	-	Amino acid permease
IOEIEHHP_00357	7.73e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOEIEHHP_00358	6.47e-209	-	-	-	S	-	-	-	reductase
IOEIEHHP_00359	8.93e-249	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOEIEHHP_00360	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IOEIEHHP_00361	4.38e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOEIEHHP_00362	5.19e-254	-	-	-	-	-	-	-	-
IOEIEHHP_00363	8.61e-167	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00364	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOEIEHHP_00365	1.63e-162	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOEIEHHP_00366	1.9e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOEIEHHP_00367	1.2e-205	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOEIEHHP_00368	7.68e-254	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOEIEHHP_00369	1.75e-135	-	-	-	-	-	-	-	-
IOEIEHHP_00371	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IOEIEHHP_00372	0.0	ycaM	-	-	E	-	-	-	amino acid
IOEIEHHP_00373	1.03e-302	xylP	-	-	G	-	-	-	MFS/sugar transport protein
IOEIEHHP_00374	1.87e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IOEIEHHP_00375	4.75e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IOEIEHHP_00376	1.27e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOEIEHHP_00378	4.46e-180	-	-	-	-	-	-	-	-
IOEIEHHP_00380	7.58e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOEIEHHP_00381	5.64e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00382	2.66e-217	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00383	9.16e-194	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00384	7.64e-223	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IOEIEHHP_00385	2.31e-69	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00386	6.85e-103	-	2.7.1.202	-	GT	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00387	5.18e-172	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_00388	8.9e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IOEIEHHP_00389	9.56e-243	tktC	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase
IOEIEHHP_00390	8.16e-206	tktN	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
IOEIEHHP_00391	5.28e-234	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00392	1.2e-59	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
IOEIEHHP_00393	8.85e-102	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00394	2.23e-166	alsE	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
IOEIEHHP_00395	7.16e-155	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOEIEHHP_00396	3.36e-202	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IOEIEHHP_00397	5.34e-64	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00398	8.5e-100	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00399	2.48e-91	-	-	-	G	ko:K02806	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00400	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
IOEIEHHP_00401	3.86e-107	-	-	-	-	-	-	-	-
IOEIEHHP_00402	1.11e-74	-	-	-	-	-	-	-	-
IOEIEHHP_00403	1.86e-42	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00404	8.52e-41	-	-	-	-	-	-	-	-
IOEIEHHP_00405	1.01e-134	-	-	-	-	-	-	-	-
IOEIEHHP_00406	1.27e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOEIEHHP_00407	3.38e-308	-	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_00408	2.13e-118	-	-	-	-	-	-	-	-
IOEIEHHP_00409	4.7e-80	-	-	-	-	-	-	-	-
IOEIEHHP_00410	3.1e-103	-	-	-	-	-	-	-	-
IOEIEHHP_00411	1.2e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOEIEHHP_00412	7.38e-67	-	-	-	-	-	-	-	-
IOEIEHHP_00413	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
IOEIEHHP_00414	1.59e-162	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IOEIEHHP_00418	7.37e-48	-	-	-	-	-	-	-	-
IOEIEHHP_00419	1.79e-57	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IOEIEHHP_00420	2.32e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOEIEHHP_00421	5.6e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IOEIEHHP_00422	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOEIEHHP_00423	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_00424	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOEIEHHP_00425	5.98e-242	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOEIEHHP_00426	0.0	-	-	-	E	-	-	-	Amino acid permease
IOEIEHHP_00427	6.61e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOEIEHHP_00428	1.43e-134	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOEIEHHP_00429	3.99e-194	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOEIEHHP_00430	8.48e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
IOEIEHHP_00431	3.15e-162	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOEIEHHP_00432	1.33e-142	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IOEIEHHP_00433	2.58e-309	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_00434	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOEIEHHP_00435	1.09e-48	-	-	-	-	-	-	-	-
IOEIEHHP_00436	8.76e-34	-	-	-	-	-	-	-	-
IOEIEHHP_00437	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
IOEIEHHP_00439	3.02e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOEIEHHP_00440	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IOEIEHHP_00441	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IOEIEHHP_00442	1.36e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IOEIEHHP_00443	8.19e-209	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOEIEHHP_00444	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IOEIEHHP_00445	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_00446	1.85e-75	-	-	-	-	-	-	-	-
IOEIEHHP_00447	2.77e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
IOEIEHHP_00448	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IOEIEHHP_00449	2.09e-242	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IOEIEHHP_00450	1.69e-162	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
IOEIEHHP_00451	7.49e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
IOEIEHHP_00452	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
IOEIEHHP_00453	7.99e-271	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IOEIEHHP_00454	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IOEIEHHP_00455	7.28e-213	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IOEIEHHP_00456	4.62e-189	gntR	-	-	K	-	-	-	rpiR family
IOEIEHHP_00457	2.19e-217	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IOEIEHHP_00458	9.82e-203	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
IOEIEHHP_00459	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
IOEIEHHP_00460	9.08e-201	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00461	2.46e-221	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOEIEHHP_00462	4.1e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOEIEHHP_00463	1.94e-246	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOEIEHHP_00464	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOEIEHHP_00465	1.62e-227	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOEIEHHP_00466	5.96e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOEIEHHP_00467	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOEIEHHP_00468	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOEIEHHP_00469	4.62e-181	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_00470	1.93e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
IOEIEHHP_00471	1.83e-180	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IOEIEHHP_00472	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOEIEHHP_00473	1.04e-110	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOEIEHHP_00474	1.85e-301	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOEIEHHP_00475	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
IOEIEHHP_00476	1.68e-156	vanR	-	-	K	-	-	-	response regulator
IOEIEHHP_00477	6.07e-155	-	-	-	-	-	-	-	-
IOEIEHHP_00478	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOEIEHHP_00479	7.99e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IOEIEHHP_00480	4.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOEIEHHP_00481	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IOEIEHHP_00482	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOEIEHHP_00483	1.28e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IOEIEHHP_00484	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOEIEHHP_00485	8.67e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IOEIEHHP_00486	8.1e-87	-	-	-	-	-	-	-	-
IOEIEHHP_00487	2.07e-164	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IOEIEHHP_00489	5.43e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IOEIEHHP_00490	1.7e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOEIEHHP_00491	5.63e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
IOEIEHHP_00492	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
IOEIEHHP_00493	3.19e-165	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOEIEHHP_00494	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOEIEHHP_00495	8.91e-59	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOEIEHHP_00496	1.32e-39	-	-	-	-	-	-	-	-
IOEIEHHP_00497	1.68e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
IOEIEHHP_00498	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
IOEIEHHP_00499	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOEIEHHP_00500	8.56e-221	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOEIEHHP_00501	4.87e-37	-	-	-	-	-	-	-	-
IOEIEHHP_00502	4.57e-49	-	-	-	-	-	-	-	-
IOEIEHHP_00503	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
IOEIEHHP_00504	2.13e-68	-	-	-	-	-	-	-	-
IOEIEHHP_00505	8.87e-85	-	-	-	-	-	-	-	-
IOEIEHHP_00506	1.47e-07	-	-	-	-	-	-	-	-
IOEIEHHP_00507	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
IOEIEHHP_00508	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOEIEHHP_00509	6.46e-302	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IOEIEHHP_00510	1.25e-149	-	-	-	-	-	-	-	-
IOEIEHHP_00511	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IOEIEHHP_00512	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
IOEIEHHP_00513	6.86e-206	-	-	-	K	ko:K20373,ko:K20374,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
IOEIEHHP_00514	1.01e-239	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_00515	3.21e-98	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_00516	1.87e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
IOEIEHHP_00517	1.24e-104	-	-	-	S	-	-	-	NUDIX domain
IOEIEHHP_00518	9.35e-99	-	-	-	-	-	-	-	-
IOEIEHHP_00519	1.62e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00520	2.65e-161	-	-	-	-	-	-	-	-
IOEIEHHP_00521	5.28e-147	-	-	-	-	-	-	-	-
IOEIEHHP_00522	4.55e-118	-	-	-	-	-	-	-	-
IOEIEHHP_00523	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOEIEHHP_00524	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IOEIEHHP_00526	4.18e-27	-	-	-	-	-	-	-	-
IOEIEHHP_00527	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_00528	7.19e-177	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
IOEIEHHP_00529	1.16e-204	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOEIEHHP_00530	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00531	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00532	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOEIEHHP_00533	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOEIEHHP_00534	4.86e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOEIEHHP_00535	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IOEIEHHP_00536	2.4e-75	-	-	-	-	-	-	-	-
IOEIEHHP_00537	8.13e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IOEIEHHP_00538	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_00539	2.83e-241	ynjC	-	-	S	-	-	-	Cell surface protein
IOEIEHHP_00540	4.34e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_00542	0.0	-	-	-	-	-	-	-	-
IOEIEHHP_00543	3.78e-137	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOEIEHHP_00544	3.34e-57	-	-	-	-	-	-	-	-
IOEIEHHP_00545	3.57e-236	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOEIEHHP_00546	6.13e-144	-	-	-	K	-	-	-	LysR substrate binding domain
IOEIEHHP_00547	0.0	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
IOEIEHHP_00548	0.0	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOEIEHHP_00549	3.27e-183	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00550	7.17e-233	-	-	-	P	ko:K15551	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
IOEIEHHP_00551	8.4e-178	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_00554	4.18e-71	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
IOEIEHHP_00555	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOEIEHHP_00556	9.85e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
IOEIEHHP_00557	5.56e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IOEIEHHP_00558	6.75e-57	-	-	-	-	-	-	-	-
IOEIEHHP_00559	9.7e-169	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
IOEIEHHP_00560	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_00561	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_00562	3.35e-111	-	-	-	-	-	-	-	-
IOEIEHHP_00563	2.83e-69	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_00564	1.73e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00565	4.75e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOEIEHHP_00566	1e-116	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
IOEIEHHP_00567	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IOEIEHHP_00568	1.19e-256	yclK	-	-	T	-	-	-	Histidine kinase
IOEIEHHP_00569	2.25e-111	-	-	-	-	-	-	-	-
IOEIEHHP_00570	6.96e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00571	7.43e-144	-	-	-	-	-	-	-	-
IOEIEHHP_00572	1.56e-55	-	-	-	-	-	-	-	-
IOEIEHHP_00573	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOEIEHHP_00574	2.67e-56	-	-	-	-	-	-	-	-
IOEIEHHP_00575	5.31e-266	mccF	-	-	V	-	-	-	LD-carboxypeptidase
IOEIEHHP_00576	5.72e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
IOEIEHHP_00577	1.05e-156	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
IOEIEHHP_00578	7.15e-164	-	-	-	-	-	-	-	-
IOEIEHHP_00579	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IOEIEHHP_00580	3.1e-130	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOEIEHHP_00581	1.16e-155	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00582	2.27e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IOEIEHHP_00583	5.44e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00584	6.1e-261	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00586	1.47e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IOEIEHHP_00587	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IOEIEHHP_00589	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOEIEHHP_00590	1.4e-262	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
IOEIEHHP_00591	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00592	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00593	9.89e-138	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOEIEHHP_00594	5.07e-202	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOEIEHHP_00595	5.42e-254	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IOEIEHHP_00596	3.05e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOEIEHHP_00597	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_00598	3.05e-282	-	-	-	-	-	-	-	-
IOEIEHHP_00599	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOEIEHHP_00600	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOEIEHHP_00601	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IOEIEHHP_00603	1.55e-193	-	-	-	EG	-	-	-	EamA-like transporter family
IOEIEHHP_00604	1.64e-98	-	-	-	L	-	-	-	NUDIX domain
IOEIEHHP_00605	8.49e-66	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_00606	8.46e-84	-	-	-	-	-	-	-	-
IOEIEHHP_00607	3.52e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOEIEHHP_00608	3.6e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOEIEHHP_00609	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOEIEHHP_00610	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOEIEHHP_00611	1.79e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOEIEHHP_00612	2.73e-285	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOEIEHHP_00613	8.2e-214	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOEIEHHP_00614	2.21e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOEIEHHP_00615	1.93e-137	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
IOEIEHHP_00617	1.67e-159	-	-	-	-	-	-	-	-
IOEIEHHP_00618	9.98e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_00619	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_00620	4.15e-234	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOEIEHHP_00621	1.37e-175	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IOEIEHHP_00622	2.53e-139	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IOEIEHHP_00623	1.67e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOEIEHHP_00624	3.66e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOEIEHHP_00626	3.33e-208	bglK_1	-	-	GK	-	-	-	ROK family
IOEIEHHP_00627	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_00628	1.05e-181	-	-	-	K	-	-	-	SIS domain
IOEIEHHP_00629	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
IOEIEHHP_00630	2.07e-106	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00631	0.0	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00632	5.29e-206	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOEIEHHP_00634	4.02e-116	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
IOEIEHHP_00635	5.03e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_00636	4.48e-152	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
IOEIEHHP_00637	2.65e-133	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IOEIEHHP_00638	4.23e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IOEIEHHP_00639	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IOEIEHHP_00641	3.6e-92	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOEIEHHP_00642	5.26e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IOEIEHHP_00643	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00644	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00645	3.39e-226	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOEIEHHP_00646	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_00648	5.87e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
IOEIEHHP_00649	4.53e-90	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
IOEIEHHP_00650	1.88e-316	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IOEIEHHP_00651	5.55e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOEIEHHP_00652	2.63e-137	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IOEIEHHP_00653	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IOEIEHHP_00655	7.98e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_00656	6.91e-280	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOEIEHHP_00657	1.98e-313	-	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_00658	1.31e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IOEIEHHP_00659	3.4e-78	ps105	-	-	-	-	-	-	-
IOEIEHHP_00660	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
IOEIEHHP_00661	1.44e-245	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_00662	1.34e-163	kdgR	-	-	K	-	-	-	FCD domain
IOEIEHHP_00663	2.3e-293	-	-	-	G	-	-	-	Major Facilitator
IOEIEHHP_00664	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
IOEIEHHP_00665	6.06e-278	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IOEIEHHP_00666	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IOEIEHHP_00667	3.83e-230	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_00668	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOEIEHHP_00670	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
IOEIEHHP_00671	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
IOEIEHHP_00672	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
IOEIEHHP_00673	1.13e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
IOEIEHHP_00674	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IOEIEHHP_00675	5.05e-66	-	-	-	-	-	-	-	-
IOEIEHHP_00676	2.7e-232	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
IOEIEHHP_00678	4.41e-67	-	-	-	-	-	-	-	-
IOEIEHHP_00679	5.63e-114	-	-	-	-	-	-	-	-
IOEIEHHP_00680	1.45e-143	-	-	-	S	-	-	-	Membrane
IOEIEHHP_00681	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOEIEHHP_00682	1.54e-73	-	-	-	-	-	-	-	-
IOEIEHHP_00683	9.22e-147	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOEIEHHP_00684	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOEIEHHP_00685	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOEIEHHP_00686	1.7e-62	-	-	-	-	-	-	-	-
IOEIEHHP_00687	8.78e-197	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOEIEHHP_00688	3.25e-125	-	-	-	K	-	-	-	transcriptional regulator
IOEIEHHP_00689	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00690	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00691	6.5e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
IOEIEHHP_00692	3.65e-274	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
IOEIEHHP_00693	1.43e-251	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
IOEIEHHP_00694	1.47e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00695	3.37e-108	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
IOEIEHHP_00696	1.96e-165	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOEIEHHP_00697	9.94e-143	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOEIEHHP_00698	1.76e-39	-	-	-	-	-	-	-	-
IOEIEHHP_00699	3.87e-238	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
IOEIEHHP_00700	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
IOEIEHHP_00701	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IOEIEHHP_00702	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOEIEHHP_00703	1.41e-130	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOEIEHHP_00704	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOEIEHHP_00705	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOEIEHHP_00706	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOEIEHHP_00710	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOEIEHHP_00711	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOEIEHHP_00712	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOEIEHHP_00713	8.07e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOEIEHHP_00714	1.21e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IOEIEHHP_00715	1.77e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOEIEHHP_00716	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOEIEHHP_00717	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IOEIEHHP_00719	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOEIEHHP_00720	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOEIEHHP_00721	5.21e-178	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IOEIEHHP_00722	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOEIEHHP_00723	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOEIEHHP_00724	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOEIEHHP_00725	6.86e-43	-	-	-	-	-	-	-	-
IOEIEHHP_00727	1.48e-172	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOEIEHHP_00728	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOEIEHHP_00729	2.27e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
IOEIEHHP_00732	7.4e-254	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
IOEIEHHP_00735	5.43e-192	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOEIEHHP_00736	1.34e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IOEIEHHP_00737	8.18e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOEIEHHP_00738	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
IOEIEHHP_00739	5.68e-242	-	-	-	-	-	-	-	-
IOEIEHHP_00740	4.13e-39	-	-	-	-	-	-	-	-
IOEIEHHP_00741	2.04e-96	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00742	7.21e-112	-	-	-	C	-	-	-	nadph quinone reductase
IOEIEHHP_00743	1.11e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOEIEHHP_00744	1.19e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00745	4.57e-197	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOEIEHHP_00746	1.31e-286	-	-	-	K	-	-	-	IrrE N-terminal-like domain
IOEIEHHP_00747	3.01e-176	-	-	-	-	-	-	-	-
IOEIEHHP_00748	1.1e-26	-	-	-	-	-	-	-	-
IOEIEHHP_00749	7.2e-60	-	-	-	-	-	-	-	-
IOEIEHHP_00750	1.35e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IOEIEHHP_00751	1.02e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOEIEHHP_00752	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00753	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
IOEIEHHP_00754	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_00755	4.29e-276	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IOEIEHHP_00756	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
IOEIEHHP_00757	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IOEIEHHP_00758	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOEIEHHP_00760	3.35e-217	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IOEIEHHP_00761	1.11e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
IOEIEHHP_00762	3.93e-90	-	-	-	-	-	-	-	-
IOEIEHHP_00763	2.39e-193	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
IOEIEHHP_00766	6.38e-88	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IOEIEHHP_00767	3.5e-143	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IOEIEHHP_00768	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IOEIEHHP_00769	3.22e-268	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOEIEHHP_00770	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
IOEIEHHP_00771	5.03e-172	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOEIEHHP_00772	2.34e-214	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOEIEHHP_00773	5.02e-134	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
IOEIEHHP_00774	1.39e-130	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOEIEHHP_00775	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_00776	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_00777	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00778	2.1e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
IOEIEHHP_00779	1.29e-184	-	-	-	S	-	-	-	AAA ATPase domain
IOEIEHHP_00780	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IOEIEHHP_00781	1.9e-104	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IOEIEHHP_00782	6.94e-70	-	-	-	-	-	-	-	-
IOEIEHHP_00783	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOEIEHHP_00784	6.34e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOEIEHHP_00785	6.61e-16	-	-	-	-	-	-	-	-
IOEIEHHP_00786	9.15e-301	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOEIEHHP_00787	1.27e-51	-	-	-	-	-	-	-	-
IOEIEHHP_00788	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_00789	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00790	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IOEIEHHP_00794	8.77e-204	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_00795	9.72e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00796	3.46e-241	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
IOEIEHHP_00797	2.3e-277	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOEIEHHP_00798	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00799	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IOEIEHHP_00800	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IOEIEHHP_00801	2.19e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
IOEIEHHP_00802	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IOEIEHHP_00803	3.51e-272	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IOEIEHHP_00804	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_00805	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
IOEIEHHP_00806	2.83e-116	-	-	-	S	-	-	-	AAA domain
IOEIEHHP_00807	1.39e-106	-	-	-	F	-	-	-	NUDIX domain
IOEIEHHP_00808	5.23e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_00809	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
IOEIEHHP_00810	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00811	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IOEIEHHP_00812	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_00813	1.51e-95	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOEIEHHP_00814	6.51e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
IOEIEHHP_00815	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOEIEHHP_00816	1.7e-300	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOEIEHHP_00817	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00818	1.29e-158	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
IOEIEHHP_00819	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOEIEHHP_00820	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOEIEHHP_00821	0.0	yycH	-	-	S	-	-	-	YycH protein
IOEIEHHP_00822	4.46e-184	yycI	-	-	S	-	-	-	YycH protein
IOEIEHHP_00823	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IOEIEHHP_00825	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IOEIEHHP_00826	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOEIEHHP_00827	7.07e-100	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
IOEIEHHP_00828	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IOEIEHHP_00829	1.1e-218	-	-	-	-	-	-	-	-
IOEIEHHP_00832	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOEIEHHP_00833	5.64e-315	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IOEIEHHP_00834	1.17e-136	-	-	-	-	-	-	-	-
IOEIEHHP_00835	3.13e-253	ysdE	-	-	P	-	-	-	Citrate transporter
IOEIEHHP_00836	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOEIEHHP_00837	3.41e-89	-	-	-	S	-	-	-	ASCH
IOEIEHHP_00838	5.06e-160	-	-	-	-	-	-	-	-
IOEIEHHP_00839	2.58e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_00840	1.67e-171	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IOEIEHHP_00841	1.94e-99	-	-	-	E	-	-	-	HAD-hyrolase-like
IOEIEHHP_00842	6.5e-105	yfbM	-	-	K	-	-	-	FR47-like protein
IOEIEHHP_00843	5.69e-140	-	-	-	S	-	-	-	alpha beta
IOEIEHHP_00844	1.78e-49	-	-	-	-	-	-	-	-
IOEIEHHP_00845	3.14e-76	-	-	-	-	-	-	-	-
IOEIEHHP_00846	1.98e-92	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_00848	1.53e-176	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_00849	6.94e-07	-	-	-	K	-	-	-	SpoVT / AbrB like domain
IOEIEHHP_00850	1.25e-67	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
IOEIEHHP_00851	3.29e-182	-	-	-	Q	-	-	-	Methyltransferase
IOEIEHHP_00852	5.84e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOEIEHHP_00853	1.24e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IOEIEHHP_00854	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IOEIEHHP_00855	8.02e-255	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
IOEIEHHP_00857	3.98e-172	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00858	7.12e-15	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00859	6.03e-159	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00860	7.93e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00861	7.77e-210	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOEIEHHP_00862	2.54e-186	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOEIEHHP_00863	1.04e-243	-	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_00864	3.41e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IOEIEHHP_00865	7.56e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOEIEHHP_00866	1.08e-267	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
IOEIEHHP_00867	1.76e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
IOEIEHHP_00868	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_00869	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOEIEHHP_00870	5.9e-92	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOEIEHHP_00871	3.53e-22	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOEIEHHP_00872	1.74e-132	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOEIEHHP_00873	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOEIEHHP_00874	1.09e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
IOEIEHHP_00875	5.05e-171	-	-	-	F	-	-	-	NUDIX domain
IOEIEHHP_00876	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOEIEHHP_00877	1.31e-127	-	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00879	3.05e-145	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IOEIEHHP_00880	3.1e-117	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IOEIEHHP_00881	5.64e-173	farR	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_00882	5.31e-206	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00883	2.18e-101	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00884	5.95e-65	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00885	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00886	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
IOEIEHHP_00887	8.85e-208	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
IOEIEHHP_00888	2e-309	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00889	7.23e-93	ahaA	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00890	8.01e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00891	4.28e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00892	1.21e-199	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00893	9.81e-261	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IOEIEHHP_00894	0.0	-	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
IOEIEHHP_00895	8.36e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
IOEIEHHP_00896	8.42e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOEIEHHP_00897	4.11e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IOEIEHHP_00898	5.02e-168	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IOEIEHHP_00899	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
IOEIEHHP_00900	1.23e-229	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IOEIEHHP_00901	1.44e-201	-	-	-	GK	-	-	-	ROK family
IOEIEHHP_00902	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IOEIEHHP_00903	2.34e-148	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOEIEHHP_00904	5.35e-232	-	1.1.1.405	-	E	ko:K05352	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IOEIEHHP_00905	8.83e-52	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00906	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
IOEIEHHP_00907	1.46e-201	is18	-	-	L	-	-	-	Integrase core domain
IOEIEHHP_00908	1.41e-29	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00909	1.72e-92	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00910	3.78e-170	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00911	7.99e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00912	4.26e-125	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOEIEHHP_00913	2.74e-35	-	-	-	K	ko:K02443	-	ko00000,ko03000	glycerol-3-phosphate responsive antiterminator
IOEIEHHP_00914	2.04e-100	-	-	-	G	-	-	-	DeoC/LacD family aldolase
IOEIEHHP_00915	7.7e-207	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IOEIEHHP_00917	1e-121	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOEIEHHP_00918	4.48e-55	-	-	-	-	-	-	-	-
IOEIEHHP_00919	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOEIEHHP_00920	1.21e-270	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
IOEIEHHP_00921	4.02e-104	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00922	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00923	2.76e-60	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00924	3.7e-148	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
IOEIEHHP_00925	2.12e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOEIEHHP_00926	3.47e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
IOEIEHHP_00927	5.06e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOEIEHHP_00928	6.13e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IOEIEHHP_00929	1.38e-183	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
IOEIEHHP_00930	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IOEIEHHP_00931	7.24e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
IOEIEHHP_00932	3e-87	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
IOEIEHHP_00933	1.88e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
IOEIEHHP_00934	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IOEIEHHP_00935	8.39e-159	-	-	-	H	-	-	-	Pfam:Transaldolase
IOEIEHHP_00936	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_00937	5.66e-72	-	-	-	S	-	-	-	PRD domain
IOEIEHHP_00938	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
IOEIEHHP_00939	1.66e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
IOEIEHHP_00940	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
IOEIEHHP_00941	3.36e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
IOEIEHHP_00942	1.23e-274	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
IOEIEHHP_00943	3.41e-257	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
IOEIEHHP_00944	9.74e-178	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
IOEIEHHP_00945	4.78e-105	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOEIEHHP_00946	2.35e-161	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOEIEHHP_00947	3.79e-135	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
IOEIEHHP_00948	1.72e-261	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IOEIEHHP_00949	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOEIEHHP_00950	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IOEIEHHP_00951	4.29e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOEIEHHP_00952	9.21e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IOEIEHHP_00953	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00954	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00955	9.75e-54	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00956	2.35e-249	-	-	-	G	-	-	-	Melibiase
IOEIEHHP_00957	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
IOEIEHHP_00959	5.2e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOEIEHHP_00960	2.29e-191	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_00961	3.4e-114	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOEIEHHP_00962	1.74e-170	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOEIEHHP_00963	1.54e-182	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOEIEHHP_00964	6.48e-140	-	-	-	K	-	-	-	Bacterial transcriptional regulator
IOEIEHHP_00965	1.2e-129	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOEIEHHP_00966	4.45e-257	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IOEIEHHP_00967	1.2e-105	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_00968	1.63e-170	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_00969	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_00970	5.11e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_00971	0.000891	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IOEIEHHP_00972	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
IOEIEHHP_00973	1.92e-99	-	-	-	-	-	-	-	-
IOEIEHHP_00974	0.0	-	-	-	M	-	-	-	Right handed beta helix region
IOEIEHHP_00975	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOEIEHHP_00976	7.4e-145	-	-	-	-	-	-	-	-
IOEIEHHP_00977	9.11e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOEIEHHP_00978	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IOEIEHHP_00979	1.04e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOEIEHHP_00980	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
IOEIEHHP_00981	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOEIEHHP_00982	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IOEIEHHP_00983	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
IOEIEHHP_00984	1.86e-212	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IOEIEHHP_00986	3.93e-156	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_00987	4.19e-89	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_00988	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00989	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_00991	1.05e-166	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
IOEIEHHP_00992	2.31e-174	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IOEIEHHP_00993	2e-301	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_00994	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
IOEIEHHP_00995	1.16e-315	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
IOEIEHHP_00996	1.63e-200	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOEIEHHP_00997	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_00998	3.76e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_00999	1.84e-65	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_01000	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_01001	4.69e-144	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOEIEHHP_01002	5.47e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_01003	4.82e-60	sgcB	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_01004	2.82e-314	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_01005	2.83e-284	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
IOEIEHHP_01006	2.08e-113	-	-	-	-	-	-	-	-
IOEIEHHP_01007	6.65e-311	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
IOEIEHHP_01008	2.35e-84	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_01009	1.75e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOEIEHHP_01010	4.24e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOEIEHHP_01011	7.89e-89	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_01012	8.18e-61	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOEIEHHP_01013	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOEIEHHP_01014	4.66e-176	-	-	-	K	-	-	-	UTRA domain
IOEIEHHP_01015	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOEIEHHP_01016	1e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOEIEHHP_01017	2.36e-217	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_01018	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_01021	6.36e-117	-	-	-	-	-	-	-	-
IOEIEHHP_01022	5.46e-13	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IOEIEHHP_01023	1.68e-119	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IOEIEHHP_01024	1.04e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOEIEHHP_01025	1.49e-74	-	-	-	-	-	-	-	-
IOEIEHHP_01026	3.7e-60	-	-	-	-	-	-	-	-
IOEIEHHP_01027	4.08e-289	-	-	-	EK	-	-	-	Aminotransferase, class I
IOEIEHHP_01028	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
IOEIEHHP_01029	3.96e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOEIEHHP_01030	3.29e-193	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IOEIEHHP_01031	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
IOEIEHHP_01032	2.88e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IOEIEHHP_01033	1.71e-17	-	-	-	-	-	-	-	-
IOEIEHHP_01034	3.33e-78	-	-	-	-	-	-	-	-
IOEIEHHP_01035	2.56e-181	-	-	-	S	-	-	-	hydrolase
IOEIEHHP_01036	2.96e-242	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IOEIEHHP_01037	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
IOEIEHHP_01038	4.69e-94	-	-	-	K	-	-	-	MarR family
IOEIEHHP_01039	7.97e-139	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOEIEHHP_01040	0.000878	PBK	2.7.11.1, 2.7.12.2	-	KLT	ko:K08843,ko:K08865	-	ko00000,ko01000,ko01001	protein kinase activity
IOEIEHHP_01041	9.35e-258	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IOEIEHHP_01042	4.43e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01043	4.2e-108	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
IOEIEHHP_01044	3.21e-176	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOEIEHHP_01045	7.84e-40	-	-	-	-	-	-	-	-
IOEIEHHP_01046	7.74e-62	-	-	-	-	-	-	-	-
IOEIEHHP_01047	8.86e-195	repA	-	-	S	-	-	-	Replication initiator protein A
IOEIEHHP_01048	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
IOEIEHHP_01049	2.25e-111	-	-	-	-	-	-	-	-
IOEIEHHP_01050	5.09e-51	-	-	-	-	-	-	-	-
IOEIEHHP_01051	3.4e-33	-	-	-	-	-	-	-	-
IOEIEHHP_01052	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
IOEIEHHP_01053	5.19e-181	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOEIEHHP_01054	1.65e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01055	5.65e-105	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01056	3.15e-161	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
IOEIEHHP_01057	2.29e-17	ohr	-	-	O	-	-	-	redox protein regulator of disulfide bond formation
IOEIEHHP_01058	2.31e-159	-	-	-	-	-	-	-	-
IOEIEHHP_01059	8.43e-71	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOEIEHHP_01060	1.11e-44	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOEIEHHP_01061	1.05e-29	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IOEIEHHP_01062	4.6e-40	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	Addiction module toxin, Txe YoeB family
IOEIEHHP_01063	5.26e-299	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOEIEHHP_01064	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
IOEIEHHP_01065	1.09e-158	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOEIEHHP_01066	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOEIEHHP_01067	4.15e-280	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IOEIEHHP_01068	3.25e-294	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IOEIEHHP_01069	1.1e-254	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOEIEHHP_01070	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_01071	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_01072	4.4e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_01073	1.2e-222	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IOEIEHHP_01074	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_01075	7.51e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IOEIEHHP_01076	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOEIEHHP_01077	5.5e-155	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IOEIEHHP_01102	2.21e-121	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
IOEIEHHP_01103	0.0	ybeC	-	-	E	-	-	-	amino acid
IOEIEHHP_01104	1.55e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IOEIEHHP_01105	4.43e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IOEIEHHP_01106	1.08e-222	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOEIEHHP_01107	1.51e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOEIEHHP_01108	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IOEIEHHP_01109	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOEIEHHP_01110	2.56e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IOEIEHHP_01111	1.1e-171	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_01112	1.24e-179	-	-	-	U	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_01113	3.07e-276	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOEIEHHP_01114	2.8e-228	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01115	2.39e-113	is18	-	-	L	-	-	-	Integrase core domain
IOEIEHHP_01116	4.05e-41	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
IOEIEHHP_01117	3.4e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
IOEIEHHP_01118	5.71e-97	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOEIEHHP_01119	1.82e-276	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IOEIEHHP_01120	2.95e-152	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
IOEIEHHP_01121	2.19e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01122	4.59e-47	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
IOEIEHHP_01123	6.89e-107	tnp2PF3	-	-	L	-	-	-	Transposase
IOEIEHHP_01124	2.83e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOEIEHHP_01125	1.64e-209	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
IOEIEHHP_01126	1.5e-178	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
IOEIEHHP_01127	0.0	-	-	-	S	-	-	-	ABC transporter
IOEIEHHP_01128	1.13e-221	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
IOEIEHHP_01129	2.96e-138	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOEIEHHP_01130	9.9e-69	-	-	-	-	-	-	-	-
IOEIEHHP_01131	2.7e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOEIEHHP_01132	4.68e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOEIEHHP_01133	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_01134	3.02e-99	-	-	-	T	-	-	-	Sh3 type 3 domain protein
IOEIEHHP_01135	9.99e-08	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOEIEHHP_01137	1.19e-14	-	-	-	-	-	-	-	-
IOEIEHHP_01139	4.81e-105	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
IOEIEHHP_01141	2.77e-157	-	-	-	S	-	-	-	AIPR protein
IOEIEHHP_01143	8.72e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
IOEIEHHP_01146	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
IOEIEHHP_01148	0.0	-	-	-	L	-	-	-	Transposase DDE domain
IOEIEHHP_01149	2.59e-278	-	-	-	L	-	-	-	Transposase
IOEIEHHP_01151	1.56e-165	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
IOEIEHHP_01152	3.06e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOEIEHHP_01153	2.79e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOEIEHHP_01154	1.49e-185	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IOEIEHHP_01155	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOEIEHHP_01156	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOEIEHHP_01157	3.2e-212	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IOEIEHHP_01158	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOEIEHHP_01159	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOEIEHHP_01160	2.78e-221	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOEIEHHP_01161	5.92e-142	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOEIEHHP_01162	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOEIEHHP_01163	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOEIEHHP_01164	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IOEIEHHP_01165	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOEIEHHP_01166	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
IOEIEHHP_01167	3.94e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IOEIEHHP_01168	1.36e-265	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IOEIEHHP_01169	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
IOEIEHHP_01170	4.44e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01171	3.37e-222	-	-	-	T	-	-	-	Histidine kinase-like ATPases
IOEIEHHP_01172	3.04e-165	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOEIEHHP_01173	3.69e-278	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOEIEHHP_01174	4.99e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01175	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01176	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
IOEIEHHP_01177	5.66e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
IOEIEHHP_01178	6.17e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOEIEHHP_01179	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
IOEIEHHP_01180	5.62e-75	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOEIEHHP_01181	3.5e-170	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOEIEHHP_01182	4.29e-174	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOEIEHHP_01183	5.71e-145	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOEIEHHP_01184	1.21e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IOEIEHHP_01185	5.99e-286	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOEIEHHP_01186	9.41e-140	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOEIEHHP_01187	2.59e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOEIEHHP_01188	1.4e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
IOEIEHHP_01189	3.8e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IOEIEHHP_01190	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
IOEIEHHP_01192	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IOEIEHHP_01193	1.43e-67	-	-	-	S	-	-	-	MazG-like family
IOEIEHHP_01194	4.5e-244	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IOEIEHHP_01195	4.63e-219	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IOEIEHHP_01196	1.19e-208	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOEIEHHP_01197	5.44e-242	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
IOEIEHHP_01198	3.21e-220	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
IOEIEHHP_01199	9.86e-221	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IOEIEHHP_01200	2.24e-290	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
IOEIEHHP_01201	7.39e-226	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
IOEIEHHP_01202	7.07e-138	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
IOEIEHHP_01203	5.68e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOEIEHHP_01204	9.32e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOEIEHHP_01205	1.8e-191	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOEIEHHP_01206	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IOEIEHHP_01207	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOEIEHHP_01208	2.64e-304	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOEIEHHP_01209	1.44e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOEIEHHP_01210	2.72e-298	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IOEIEHHP_01211	7.77e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOEIEHHP_01213	3.23e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOEIEHHP_01214	2.83e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOEIEHHP_01215	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IOEIEHHP_01216	2.01e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
IOEIEHHP_01217	2.28e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IOEIEHHP_01218	9.94e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IOEIEHHP_01219	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOEIEHHP_01220	2.23e-71	-	-	-	-	-	-	-	-
IOEIEHHP_01221	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_01222	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOEIEHHP_01223	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOEIEHHP_01224	1.46e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOEIEHHP_01225	1.47e-209	lysR	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_01226	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IOEIEHHP_01227	2.36e-247	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IOEIEHHP_01228	2.09e-45	-	-	-	-	-	-	-	-
IOEIEHHP_01229	4.44e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOEIEHHP_01230	4.12e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IOEIEHHP_01232	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOEIEHHP_01233	7.64e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IOEIEHHP_01234	4.21e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOEIEHHP_01235	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IOEIEHHP_01236	1.11e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IOEIEHHP_01237	2.81e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOEIEHHP_01238	2.33e-143	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IOEIEHHP_01239	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IOEIEHHP_01240	3.43e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOEIEHHP_01241	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IOEIEHHP_01242	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IOEIEHHP_01243	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IOEIEHHP_01244	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOEIEHHP_01245	1.46e-212	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IOEIEHHP_01246	3.66e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IOEIEHHP_01247	2.87e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOEIEHHP_01248	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IOEIEHHP_01249	6.55e-224	-	-	-	-	-	-	-	-
IOEIEHHP_01250	2.93e-180	-	-	-	-	-	-	-	-
IOEIEHHP_01251	4.01e-80	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IOEIEHHP_01252	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IOEIEHHP_01253	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
IOEIEHHP_01254	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_01255	2.22e-188	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOEIEHHP_01256	4.11e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IOEIEHHP_01257	1.41e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOEIEHHP_01258	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOEIEHHP_01259	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IOEIEHHP_01260	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IOEIEHHP_01261	1.91e-120	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOEIEHHP_01263	5.18e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_01264	3.11e-71	-	-	-	-	-	-	-	-
IOEIEHHP_01265	8.93e-191	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOEIEHHP_01266	1.94e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOEIEHHP_01267	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOEIEHHP_01268	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IOEIEHHP_01269	1.03e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOEIEHHP_01270	6.59e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IOEIEHHP_01271	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IOEIEHHP_01272	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IOEIEHHP_01273	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOEIEHHP_01274	3.62e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOEIEHHP_01275	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOEIEHHP_01276	2.55e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IOEIEHHP_01277	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOEIEHHP_01278	7.34e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IOEIEHHP_01279	0.0	-	-	-	-	-	-	-	-
IOEIEHHP_01280	3.99e-200	-	-	-	V	-	-	-	ABC transporter
IOEIEHHP_01281	1.04e-104	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
IOEIEHHP_01282	9.45e-317	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IOEIEHHP_01283	5.95e-147	-	-	-	J	-	-	-	HAD-hyrolase-like
IOEIEHHP_01284	2.64e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOEIEHHP_01285	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOEIEHHP_01286	2.42e-70	-	-	-	-	-	-	-	-
IOEIEHHP_01287	1.05e-166	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOEIEHHP_01288	5.37e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IOEIEHHP_01289	6.03e-114	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
IOEIEHHP_01290	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IOEIEHHP_01291	1.1e-50	-	-	-	-	-	-	-	-
IOEIEHHP_01292	3.03e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOEIEHHP_01293	2e-36	-	-	-	-	-	-	-	-
IOEIEHHP_01294	2.8e-79	-	-	-	-	-	-	-	-
IOEIEHHP_01296	3.23e-27	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
IOEIEHHP_01297	3.16e-186	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
IOEIEHHP_01298	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
IOEIEHHP_01299	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOEIEHHP_01300	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOEIEHHP_01301	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IOEIEHHP_01302	2.01e-81	-	-	-	-	-	-	-	-
IOEIEHHP_01303	1.33e-105	-	-	-	S	-	-	-	ASCH
IOEIEHHP_01304	4.01e-44	-	-	-	-	-	-	-	-
IOEIEHHP_01305	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOEIEHHP_01306	2.45e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOEIEHHP_01307	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOEIEHHP_01308	2.41e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOEIEHHP_01309	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOEIEHHP_01311	4.19e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOEIEHHP_01312	2.11e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IOEIEHHP_01313	2.7e-203	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOEIEHHP_01314	1.91e-152	yceF	-	-	P	ko:K05794	-	ko00000	membrane
IOEIEHHP_01315	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOEIEHHP_01316	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOEIEHHP_01317	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
IOEIEHHP_01318	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IOEIEHHP_01319	4.49e-278	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOEIEHHP_01320	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IOEIEHHP_01321	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOEIEHHP_01322	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOEIEHHP_01323	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IOEIEHHP_01324	4.82e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IOEIEHHP_01325	8.75e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOEIEHHP_01326	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOEIEHHP_01327	9.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOEIEHHP_01328	3.83e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOEIEHHP_01329	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOEIEHHP_01330	0.0	-	-	-	L	-	-	-	PFAM Integrase core domain
IOEIEHHP_01331	4.52e-60	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IOEIEHHP_01332	8.66e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IOEIEHHP_01333	4.02e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IOEIEHHP_01334	1.64e-300	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IOEIEHHP_01335	7.66e-178	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
IOEIEHHP_01336	1.45e-63	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
IOEIEHHP_01337	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
IOEIEHHP_01338	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_01339	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_01340	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IOEIEHHP_01341	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
IOEIEHHP_01342	6.28e-35	-	-	-	-	-	-	-	-
IOEIEHHP_01343	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOEIEHHP_01344	7.48e-190	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOEIEHHP_01345	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOEIEHHP_01346	6.31e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOEIEHHP_01347	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOEIEHHP_01348	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOEIEHHP_01349	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOEIEHHP_01350	1.21e-32	-	-	-	-	-	-	-	-
IOEIEHHP_01351	6.51e-69	-	-	-	-	-	-	-	-
IOEIEHHP_01352	3.16e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOEIEHHP_01353	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOEIEHHP_01354	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOEIEHHP_01355	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOEIEHHP_01356	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_01357	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_01358	1.39e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOEIEHHP_01359	2.99e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOEIEHHP_01360	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOEIEHHP_01361	1.72e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOEIEHHP_01362	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOEIEHHP_01363	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IOEIEHHP_01364	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOEIEHHP_01365	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IOEIEHHP_01366	2.82e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IOEIEHHP_01367	2.81e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOEIEHHP_01368	1.12e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOEIEHHP_01369	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOEIEHHP_01370	4.47e-175	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IOEIEHHP_01371	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOEIEHHP_01372	1.68e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOEIEHHP_01373	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOEIEHHP_01374	3.26e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOEIEHHP_01375	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOEIEHHP_01376	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOEIEHHP_01377	1.89e-157	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
IOEIEHHP_01378	6.65e-67	-	-	-	-	-	-	-	-
IOEIEHHP_01379	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOEIEHHP_01380	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOEIEHHP_01381	9.45e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IOEIEHHP_01382	4.58e-186	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOEIEHHP_01383	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOEIEHHP_01384	2.22e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOEIEHHP_01385	5.67e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOEIEHHP_01386	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOEIEHHP_01387	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IOEIEHHP_01388	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOEIEHHP_01389	1.51e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOEIEHHP_01390	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IOEIEHHP_01391	2.42e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IOEIEHHP_01392	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOEIEHHP_01393	1.88e-43	-	-	-	-	-	-	-	-
IOEIEHHP_01394	1.77e-20	-	-	-	-	-	-	-	-
IOEIEHHP_01395	7.4e-295	-	-	-	S	-	-	-	Membrane
IOEIEHHP_01397	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOEIEHHP_01398	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOEIEHHP_01399	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOEIEHHP_01400	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IOEIEHHP_01401	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IOEIEHHP_01402	5.77e-306	ynbB	-	-	P	-	-	-	aluminum resistance
IOEIEHHP_01403	4.85e-231	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOEIEHHP_01404	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IOEIEHHP_01405	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IOEIEHHP_01406	4.82e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IOEIEHHP_01407	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IOEIEHHP_01408	1.49e-155	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IOEIEHHP_01409	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOEIEHHP_01410	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOEIEHHP_01411	1.57e-69	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IOEIEHHP_01412	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
IOEIEHHP_01413	5.63e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOEIEHHP_01414	3.99e-167	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IOEIEHHP_01415	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOEIEHHP_01416	1.45e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IOEIEHHP_01417	5.55e-267	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOEIEHHP_01418	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOEIEHHP_01419	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOEIEHHP_01420	1.44e-90	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IOEIEHHP_01421	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOEIEHHP_01422	1.01e-174	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOEIEHHP_01423	4.33e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IOEIEHHP_01424	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOEIEHHP_01425	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOEIEHHP_01426	1.01e-157	csrR	-	-	K	-	-	-	response regulator
IOEIEHHP_01427	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOEIEHHP_01428	2.79e-123	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IOEIEHHP_01429	8.84e-266	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IOEIEHHP_01430	4.16e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
IOEIEHHP_01431	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOEIEHHP_01432	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IOEIEHHP_01433	9.8e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOEIEHHP_01434	3.25e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IOEIEHHP_01435	5.63e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IOEIEHHP_01436	1.69e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IOEIEHHP_01437	8.54e-215	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOEIEHHP_01438	3.74e-241	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOEIEHHP_01439	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
IOEIEHHP_01440	1.02e-229	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
IOEIEHHP_01441	1.17e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOEIEHHP_01442	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOEIEHHP_01443	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IOEIEHHP_01444	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOEIEHHP_01445	1.95e-94	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_01446	3.42e-295	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOEIEHHP_01447	6.63e-173	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOEIEHHP_01448	2.49e-162	-	-	-	S	-	-	-	SseB protein N-terminal domain
IOEIEHHP_01449	2.05e-86	-	-	-	-	-	-	-	-
IOEIEHHP_01450	3.72e-77	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
IOEIEHHP_01451	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOEIEHHP_01452	1.12e-216	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IOEIEHHP_01453	3.71e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IOEIEHHP_01454	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOEIEHHP_01455	1.15e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOEIEHHP_01456	1.25e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOEIEHHP_01457	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOEIEHHP_01458	4.05e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
IOEIEHHP_01460	2.16e-241	-	-	-	S	-	-	-	Cell surface protein
IOEIEHHP_01462	1.73e-175	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_01463	0.0	-	-	-	N	-	-	-	domain, Protein
IOEIEHHP_01464	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_01465	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOEIEHHP_01466	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOEIEHHP_01468	4e-147	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOEIEHHP_01469	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IOEIEHHP_01471	9.12e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOEIEHHP_01472	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
IOEIEHHP_01473	5.12e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_01474	8.67e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01475	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IOEIEHHP_01476	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
IOEIEHHP_01477	2.05e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOEIEHHP_01478	1.25e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOEIEHHP_01479	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
IOEIEHHP_01480	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOEIEHHP_01481	8.44e-200	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOEIEHHP_01482	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOEIEHHP_01483	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOEIEHHP_01485	1.97e-88	-	-	-	-	-	-	-	-
IOEIEHHP_01486	5.54e-30	-	-	-	-	-	-	-	-
IOEIEHHP_01487	3.26e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
IOEIEHHP_01488	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IOEIEHHP_01489	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOEIEHHP_01490	1.8e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOEIEHHP_01491	9.8e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOEIEHHP_01492	9.97e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOEIEHHP_01493	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IOEIEHHP_01494	6.57e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_01495	3.79e-157	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IOEIEHHP_01496	1.71e-262	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
IOEIEHHP_01497	1.09e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOEIEHHP_01498	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
IOEIEHHP_01499	6.75e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IOEIEHHP_01500	4.95e-288	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOEIEHHP_01501	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOEIEHHP_01502	4.58e-128	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOEIEHHP_01503	1.52e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOEIEHHP_01504	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOEIEHHP_01505	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOEIEHHP_01506	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOEIEHHP_01507	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOEIEHHP_01508	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOEIEHHP_01509	1.74e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOEIEHHP_01510	3.48e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOEIEHHP_01511	2.72e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IOEIEHHP_01513	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOEIEHHP_01514	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOEIEHHP_01515	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IOEIEHHP_01516	6.69e-39	-	-	-	-	-	-	-	-
IOEIEHHP_01517	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IOEIEHHP_01518	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IOEIEHHP_01519	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOEIEHHP_01520	7.65e-307	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IOEIEHHP_01521	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
IOEIEHHP_01522	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01523	1.16e-124	-	-	-	-	-	-	-	-
IOEIEHHP_01524	4.26e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IOEIEHHP_01525	1.37e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IOEIEHHP_01526	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_01527	2.61e-83	-	-	-	-	-	-	-	-
IOEIEHHP_01528	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOEIEHHP_01529	9.69e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IOEIEHHP_01530	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOEIEHHP_01532	1.24e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IOEIEHHP_01533	2.72e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IOEIEHHP_01534	1.64e-264	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOEIEHHP_01535	6.96e-64	-	-	-	-	-	-	-	-
IOEIEHHP_01536	9.55e-205	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IOEIEHHP_01537	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
IOEIEHHP_01538	1.41e-202	-	-	-	G	-	-	-	Aldose 1-epimerase
IOEIEHHP_01539	7.93e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IOEIEHHP_01540	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IOEIEHHP_01542	3.29e-104	-	-	-	K	-	-	-	FR47-like protein
IOEIEHHP_01543	1.53e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IOEIEHHP_01544	1.59e-165	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01545	7.2e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOEIEHHP_01546	4.41e-224	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_01547	4.59e-93	-	-	-	-	-	-	-	-
IOEIEHHP_01548	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IOEIEHHP_01549	4.12e-275	-	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_01550	1.45e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOEIEHHP_01551	5.31e-284	-	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_01552	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOEIEHHP_01553	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IOEIEHHP_01554	2.91e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOEIEHHP_01555	4.58e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOEIEHHP_01556	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
IOEIEHHP_01557	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IOEIEHHP_01558	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOEIEHHP_01560	9.9e-203	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOEIEHHP_01561	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IOEIEHHP_01562	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01563	2.43e-87	-	-	-	-	-	-	-	-
IOEIEHHP_01564	1.39e-96	-	-	-	S	-	-	-	function, without similarity to other proteins
IOEIEHHP_01565	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
IOEIEHHP_01566	1.89e-266	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOEIEHHP_01567	3.89e-75	-	-	-	-	-	-	-	-
IOEIEHHP_01568	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IOEIEHHP_01569	3.18e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
IOEIEHHP_01570	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IOEIEHHP_01571	2.5e-106	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
IOEIEHHP_01572	2.11e-171	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IOEIEHHP_01573	1.12e-115	-	-	-	E	-	-	-	AAA domain
IOEIEHHP_01576	5.07e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IOEIEHHP_01577	5.61e-118	-	-	-	S	-	-	-	MucBP domain
IOEIEHHP_01578	5.24e-113	-	-	-	-	-	-	-	-
IOEIEHHP_01580	3.62e-54	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOEIEHHP_01581	2.57e-204	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
IOEIEHHP_01582	1.45e-46	-	-	-	-	-	-	-	-
IOEIEHHP_01583	7.15e-73	XK27_02555	-	-	-	-	-	-	-
IOEIEHHP_01584	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOEIEHHP_01585	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IOEIEHHP_01586	6.97e-126	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOEIEHHP_01587	1.02e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IOEIEHHP_01588	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOEIEHHP_01589	1.18e-191	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IOEIEHHP_01590	6.14e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IOEIEHHP_01591	6.29e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOEIEHHP_01592	1.03e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOEIEHHP_01593	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01594	2.08e-110	-	-	-	-	-	-	-	-
IOEIEHHP_01595	3.2e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOEIEHHP_01596	1.71e-206	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOEIEHHP_01597	4.71e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IOEIEHHP_01598	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOEIEHHP_01599	5.22e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOEIEHHP_01600	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOEIEHHP_01601	4.45e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IOEIEHHP_01602	6.23e-87	-	-	-	M	-	-	-	Lysin motif
IOEIEHHP_01603	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOEIEHHP_01604	3.43e-236	-	-	-	S	-	-	-	Helix-turn-helix domain
IOEIEHHP_01605	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
IOEIEHHP_01606	4.54e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOEIEHHP_01607	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOEIEHHP_01608	6.34e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOEIEHHP_01609	2.56e-162	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOEIEHHP_01610	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOEIEHHP_01611	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IOEIEHHP_01612	1.26e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IOEIEHHP_01613	6.13e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
IOEIEHHP_01614	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IOEIEHHP_01615	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOEIEHHP_01616	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IOEIEHHP_01617	2.92e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IOEIEHHP_01618	2.15e-187	-	-	-	-	-	-	-	-
IOEIEHHP_01619	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
IOEIEHHP_01620	3.94e-122	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IOEIEHHP_01621	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOEIEHHP_01622	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOEIEHHP_01623	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IOEIEHHP_01624	9e-182	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
IOEIEHHP_01625	3.56e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOEIEHHP_01626	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IOEIEHHP_01627	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOEIEHHP_01628	5.84e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_01629	2.09e-213	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOEIEHHP_01630	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IOEIEHHP_01631	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOEIEHHP_01632	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01633	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_01634	2.34e-28	-	-	-	-	-	-	-	-
IOEIEHHP_01635	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IOEIEHHP_01636	5.12e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IOEIEHHP_01637	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOEIEHHP_01638	4.81e-270	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOEIEHHP_01639	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IOEIEHHP_01640	5.91e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOEIEHHP_01641	4.55e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOEIEHHP_01642	8.39e-171	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOEIEHHP_01643	3.26e-108	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IOEIEHHP_01644	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOEIEHHP_01645	2.82e-205	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOEIEHHP_01646	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOEIEHHP_01647	1.17e-152	-	-	-	-	-	-	-	-
IOEIEHHP_01648	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOEIEHHP_01649	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOEIEHHP_01650	5.79e-247	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOEIEHHP_01651	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IOEIEHHP_01652	1.27e-143	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IOEIEHHP_01653	3.95e-245	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOEIEHHP_01654	1.71e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOEIEHHP_01655	2.89e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IOEIEHHP_01656	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IOEIEHHP_01657	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOEIEHHP_01658	1.31e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOEIEHHP_01659	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IOEIEHHP_01660	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IOEIEHHP_01661	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IOEIEHHP_01662	2.05e-200	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
IOEIEHHP_01663	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IOEIEHHP_01664	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOEIEHHP_01665	4.67e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IOEIEHHP_01666	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IOEIEHHP_01667	8.12e-174	-	-	-	S	-	-	-	E1-E2 ATPase
IOEIEHHP_01668	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOEIEHHP_01669	3.16e-36	-	-	-	-	-	-	-	-
IOEIEHHP_01670	1.2e-95	-	-	-	-	-	-	-	-
IOEIEHHP_01672	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IOEIEHHP_01673	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOEIEHHP_01674	7.21e-236	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOEIEHHP_01675	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
IOEIEHHP_01676	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOEIEHHP_01677	7.96e-148	-	-	-	S	-	-	-	repeat protein
IOEIEHHP_01678	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IOEIEHHP_01679	8.38e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOEIEHHP_01680	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
IOEIEHHP_01681	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IOEIEHHP_01682	3.82e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IOEIEHHP_01683	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOEIEHHP_01684	1.36e-46	-	-	-	-	-	-	-	-
IOEIEHHP_01685	7.71e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IOEIEHHP_01686	1.39e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOEIEHHP_01687	6e-268	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
IOEIEHHP_01688	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_01689	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOEIEHHP_01690	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IOEIEHHP_01691	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOEIEHHP_01692	8.06e-114	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
IOEIEHHP_01693	1.57e-184	ylmH	-	-	S	-	-	-	S4 domain protein
IOEIEHHP_01694	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
IOEIEHHP_01695	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOEIEHHP_01696	1.09e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOEIEHHP_01697	6.05e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOEIEHHP_01698	3.84e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOEIEHHP_01699	1.5e-254	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOEIEHHP_01700	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOEIEHHP_01701	3.67e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOEIEHHP_01702	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOEIEHHP_01703	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
IOEIEHHP_01704	6.49e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOEIEHHP_01705	9.34e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOEIEHHP_01706	1.49e-70	-	-	-	-	-	-	-	-
IOEIEHHP_01707	2.02e-09	-	-	-	-	-	-	-	-
IOEIEHHP_01708	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IOEIEHHP_01709	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOEIEHHP_01710	5.69e-194	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IOEIEHHP_01711	1.29e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_01712	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOEIEHHP_01713	3.51e-181	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IOEIEHHP_01714	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOEIEHHP_01715	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IOEIEHHP_01716	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IOEIEHHP_01717	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IOEIEHHP_01718	8.02e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IOEIEHHP_01719	5.68e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOEIEHHP_01720	4.4e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IOEIEHHP_01721	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOEIEHHP_01722	1.97e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
IOEIEHHP_01723	4.95e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOEIEHHP_01724	8.98e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IOEIEHHP_01725	7.64e-11	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOEIEHHP_01726	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOEIEHHP_01727	2.89e-110	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IOEIEHHP_01728	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOEIEHHP_01729	0.0	-	-	-	L	-	-	-	AAA domain
IOEIEHHP_01730	3.01e-23	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOEIEHHP_01731	4.59e-289	-	-	-	E	-	-	-	Amino acid permease
IOEIEHHP_01732	3.42e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IOEIEHHP_01733	1.6e-107	-	-	-	-	-	-	-	-
IOEIEHHP_01734	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IOEIEHHP_01735	7.43e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01736	6.73e-190	-	-	-	-	-	-	-	-
IOEIEHHP_01737	0.0	-	-	-	-	-	-	-	-
IOEIEHHP_01738	1.57e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_01739	2.07e-163	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOEIEHHP_01740	1.98e-257	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOEIEHHP_01741	5.07e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
IOEIEHHP_01742	1.32e-25	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IOEIEHHP_01744	8.67e-126	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOEIEHHP_01745	5.91e-199	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IOEIEHHP_01746	6.61e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01747	1.21e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01748	5.87e-112	-	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOEIEHHP_01749	6.4e-168	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
IOEIEHHP_01750	6.56e-34	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOEIEHHP_01751	2.48e-48	-	-	-	-	-	-	-	-
IOEIEHHP_01752	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOEIEHHP_01753	1.63e-103	yphH	-	-	S	-	-	-	Cupin domain
IOEIEHHP_01754	4.03e-206	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_01755	1.25e-165	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOEIEHHP_01756	1.86e-214	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOEIEHHP_01757	5.03e-154	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOEIEHHP_01758	7.74e-203	-	-	-	T	-	-	-	GHKL domain
IOEIEHHP_01759	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOEIEHHP_01760	1.65e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
IOEIEHHP_01761	6.87e-172	-	-	-	F	-	-	-	deoxynucleoside kinase
IOEIEHHP_01762	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IOEIEHHP_01763	1.31e-215	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
IOEIEHHP_01764	2.32e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOEIEHHP_01765	7.12e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOEIEHHP_01766	4.99e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOEIEHHP_01767	2.93e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IOEIEHHP_01768	6.44e-139	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IOEIEHHP_01769	3.28e-95	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOEIEHHP_01770	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
IOEIEHHP_01771	4.37e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IOEIEHHP_01772	0.000345	-	-	-	-	-	-	-	-
IOEIEHHP_01773	8.18e-53	-	-	-	-	-	-	-	-
IOEIEHHP_01774	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
IOEIEHHP_01775	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_01776	1.5e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IOEIEHHP_01777	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOEIEHHP_01778	2.14e-36	-	-	-	-	-	-	-	-
IOEIEHHP_01779	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IOEIEHHP_01780	1.17e-101	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IOEIEHHP_01781	4.84e-282	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOEIEHHP_01782	1.04e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IOEIEHHP_01783	9.79e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IOEIEHHP_01784	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOEIEHHP_01785	2.43e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOEIEHHP_01786	8.69e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOEIEHHP_01788	1.28e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOEIEHHP_01789	1.48e-271	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IOEIEHHP_01790	1.41e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
IOEIEHHP_01791	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IOEIEHHP_01792	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IOEIEHHP_01793	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IOEIEHHP_01794	3.18e-34	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
IOEIEHHP_01795	2.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IOEIEHHP_01796	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IOEIEHHP_01797	5.03e-22	-	-	-	-	-	-	-	-
IOEIEHHP_01798	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOEIEHHP_01799	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOEIEHHP_01800	3.68e-15	-	-	-	-	-	-	-	-
IOEIEHHP_01801	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOEIEHHP_01802	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOEIEHHP_01803	4.59e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOEIEHHP_01804	1.03e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOEIEHHP_01805	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOEIEHHP_01806	4.11e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOEIEHHP_01807	1.51e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOEIEHHP_01808	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOEIEHHP_01809	4.24e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOEIEHHP_01810	1.85e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOEIEHHP_01811	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOEIEHHP_01812	8.22e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IOEIEHHP_01813	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IOEIEHHP_01814	2.47e-252	ampC	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_01815	5.78e-212	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IOEIEHHP_01816	1.29e-181	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IOEIEHHP_01817	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOEIEHHP_01818	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_01819	1.29e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_01820	6.73e-163	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
IOEIEHHP_01823	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOEIEHHP_01824	3.41e-248	yttB	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_01825	1.56e-25	-	-	-	-	-	-	-	-
IOEIEHHP_01827	2.6e-106	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
IOEIEHHP_01828	1.27e-219	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
IOEIEHHP_01829	9.25e-293	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
IOEIEHHP_01830	2.53e-105	-	-	-	S	-	-	-	Pfam Transposase IS66
IOEIEHHP_01831	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IOEIEHHP_01832	8.64e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOEIEHHP_01834	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOEIEHHP_01835	1.9e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IOEIEHHP_01836	1.31e-142	vanZ	-	-	V	-	-	-	VanZ like family
IOEIEHHP_01837	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOEIEHHP_01838	2.76e-165	-	-	-	-	-	-	-	-
IOEIEHHP_01839	7.35e-134	-	-	-	-	-	-	-	-
IOEIEHHP_01840	5.79e-316	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOEIEHHP_01841	3.45e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOEIEHHP_01842	2.65e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IOEIEHHP_01843	6.51e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOEIEHHP_01844	1.84e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IOEIEHHP_01845	4.85e-106	yvbK	-	-	K	-	-	-	GNAT family
IOEIEHHP_01846	9.75e-32	-	-	-	T	-	-	-	PFAM SpoVT AbrB
IOEIEHHP_01847	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IOEIEHHP_01848	9.9e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IOEIEHHP_01849	5.01e-142	-	-	-	-	-	-	-	-
IOEIEHHP_01850	3.64e-221	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IOEIEHHP_01851	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOEIEHHP_01852	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOEIEHHP_01853	9.15e-238	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_01854	5.77e-114	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_01855	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_01856	1.32e-124	-	-	-	N	-	-	-	domain, Protein
IOEIEHHP_01857	6.52e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOEIEHHP_01858	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IOEIEHHP_01859	3.93e-166	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
IOEIEHHP_01860	1.23e-39	-	-	-	-	-	-	-	-
IOEIEHHP_01862	1.6e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOEIEHHP_01863	2.34e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IOEIEHHP_01864	3.05e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IOEIEHHP_01865	1.49e-228	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IOEIEHHP_01866	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IOEIEHHP_01868	3.46e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_01869	5.28e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
IOEIEHHP_01870	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOEIEHHP_01871	2.25e-07	-	-	-	-	-	-	-	-
IOEIEHHP_01873	9.05e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOEIEHHP_01875	8.36e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_01876	7.24e-301	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IOEIEHHP_01877	7.7e-227	mocA	-	-	S	-	-	-	Oxidoreductase
IOEIEHHP_01878	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IOEIEHHP_01879	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOEIEHHP_01880	1.28e-171	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IOEIEHHP_01881	1.05e-40	-	-	-	-	-	-	-	-
IOEIEHHP_01882	1.95e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IOEIEHHP_01883	5.78e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IOEIEHHP_01884	3.07e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_01885	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IOEIEHHP_01886	2.97e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IOEIEHHP_01887	3.82e-188	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOEIEHHP_01888	4.14e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_01889	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOEIEHHP_01890	1.42e-247	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IOEIEHHP_01891	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOEIEHHP_01892	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOEIEHHP_01893	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOEIEHHP_01894	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
IOEIEHHP_01895	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOEIEHHP_01896	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IOEIEHHP_01897	1.92e-53	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IOEIEHHP_01898	2.31e-162	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
IOEIEHHP_01899	4.8e-273	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IOEIEHHP_01901	2.29e-244	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOEIEHHP_01903	9.56e-317	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IOEIEHHP_01904	5.76e-77	-	-	-	-	-	-	-	-
IOEIEHHP_01905	2.24e-106	-	-	-	-	-	-	-	-
IOEIEHHP_01906	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IOEIEHHP_01907	2.21e-42	-	-	-	-	-	-	-	-
IOEIEHHP_01908	3.15e-120	-	-	-	S	-	-	-	acetyltransferase
IOEIEHHP_01909	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IOEIEHHP_01910	3.15e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IOEIEHHP_01911	3.12e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOEIEHHP_01913	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOEIEHHP_01914	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
IOEIEHHP_01915	2.3e-23	-	-	-	-	-	-	-	-
IOEIEHHP_01916	1.37e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
IOEIEHHP_01917	4.43e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOEIEHHP_01918	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
IOEIEHHP_01919	1.39e-277	-	-	-	S	-	-	-	Phage portal protein
IOEIEHHP_01920	1.04e-29	-	-	-	-	-	-	-	-
IOEIEHHP_01921	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
IOEIEHHP_01922	9.4e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
IOEIEHHP_01925	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
IOEIEHHP_01926	3.87e-199	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
IOEIEHHP_01928	1.38e-20	-	-	-	-	-	-	-	-
IOEIEHHP_01929	1.33e-78	-	-	-	-	-	-	-	-
IOEIEHHP_01930	7.55e-58	-	-	-	-	-	-	-	-
IOEIEHHP_01931	2.32e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOEIEHHP_01932	2.48e-274	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOEIEHHP_01933	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IOEIEHHP_01934	6.04e-217	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IOEIEHHP_01935	1.98e-234	arbY	-	-	M	-	-	-	family 8
IOEIEHHP_01936	2.87e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IOEIEHHP_01937	1.07e-190	arbV	-	-	I	-	-	-	Phosphate acyltransferases
IOEIEHHP_01938	1.83e-316	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IOEIEHHP_01939	1.35e-97	-	-	-	-	-	-	-	-
IOEIEHHP_01940	9.09e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IOEIEHHP_01949	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IOEIEHHP_01950	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOEIEHHP_01951	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOEIEHHP_01952	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOEIEHHP_01953	9.92e-110	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
IOEIEHHP_01954	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOEIEHHP_01955	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOEIEHHP_01956	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOEIEHHP_01957	1.43e-251	-	-	-	K	-	-	-	WYL domain
IOEIEHHP_01958	1.68e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
IOEIEHHP_01959	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IOEIEHHP_01960	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOEIEHHP_01961	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOEIEHHP_01962	4e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOEIEHHP_01963	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOEIEHHP_01964	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOEIEHHP_01965	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOEIEHHP_01966	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOEIEHHP_01967	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOEIEHHP_01968	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOEIEHHP_01969	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOEIEHHP_01970	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOEIEHHP_01971	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOEIEHHP_01972	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOEIEHHP_01973	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOEIEHHP_01974	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOEIEHHP_01975	7.47e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOEIEHHP_01976	2.3e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOEIEHHP_01977	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOEIEHHP_01978	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IOEIEHHP_01979	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOEIEHHP_01980	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOEIEHHP_01981	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOEIEHHP_01982	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOEIEHHP_01983	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOEIEHHP_01984	2.66e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOEIEHHP_01985	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOEIEHHP_01986	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOEIEHHP_01987	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOEIEHHP_01988	4.67e-155	-	-	-	-	-	-	-	-
IOEIEHHP_01989	2.32e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOEIEHHP_01990	4.3e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOEIEHHP_01991	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOEIEHHP_01992	3.99e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOEIEHHP_01994	7.1e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IOEIEHHP_01996	1.28e-45	-	-	-	-	-	-	-	-
IOEIEHHP_01997	1.56e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_01998	2.91e-235	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOEIEHHP_01999	1.76e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_02000	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOEIEHHP_02001	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOEIEHHP_02002	8.8e-265	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOEIEHHP_02003	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOEIEHHP_02004	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOEIEHHP_02006	3.43e-18	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOEIEHHP_02007	8.73e-13	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOEIEHHP_02008	5.25e-157	-	-	-	S	-	-	-	B3/4 domain
IOEIEHHP_02009	3.03e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOEIEHHP_02010	1.12e-152	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_02011	7.21e-301	-	-	-	I	-	-	-	Acyltransferase family
IOEIEHHP_02012	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
IOEIEHHP_02013	3.2e-218	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
IOEIEHHP_02014	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
IOEIEHHP_02015	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IOEIEHHP_02016	1.3e-90	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOEIEHHP_02017	2.83e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOEIEHHP_02018	3.81e-153	-	-	-	-	-	-	-	-
IOEIEHHP_02019	7.32e-28	-	-	-	-	-	-	-	-
IOEIEHHP_02020	1.21e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOEIEHHP_02021	7.54e-113	-	-	-	-	-	-	-	-
IOEIEHHP_02022	1.64e-151	-	-	-	GM	-	-	-	NmrA-like family
IOEIEHHP_02023	1.12e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOEIEHHP_02024	2.39e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOEIEHHP_02025	2.78e-169	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOEIEHHP_02026	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IOEIEHHP_02027	3.65e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOEIEHHP_02028	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IOEIEHHP_02029	4.84e-144	-	-	-	P	-	-	-	Cation efflux family
IOEIEHHP_02030	2.5e-34	-	-	-	-	-	-	-	-
IOEIEHHP_02031	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
IOEIEHHP_02032	1.61e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_02033	4.42e-84	-	-	-	-	-	-	-	-
IOEIEHHP_02034	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IOEIEHHP_02035	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOEIEHHP_02036	7.48e-25	-	-	-	-	-	-	-	-
IOEIEHHP_02037	5.43e-173	-	-	-	-	-	-	-	-
IOEIEHHP_02038	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOEIEHHP_02039	3.11e-31	-	-	-	S	-	-	-	Short C-terminal domain
IOEIEHHP_02040	1.33e-273	yqiG	-	-	C	-	-	-	Oxidoreductase
IOEIEHHP_02041	4.27e-167	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOEIEHHP_02042	9.77e-230	ydhF	-	-	S	-	-	-	Aldo keto reductase
IOEIEHHP_02043	4.57e-71	-	-	-	S	-	-	-	Enterocin A Immunity
IOEIEHHP_02044	6.09e-70	-	-	-	-	-	-	-	-
IOEIEHHP_02045	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOEIEHHP_02046	2.35e-91	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_02047	1.52e-172	-	-	-	S	-	-	-	CAAX protease self-immunity
IOEIEHHP_02052	1.93e-31	-	-	-	-	-	-	-	-
IOEIEHHP_02053	1.11e-60	-	-	-	S	-	-	-	Enterocin A Immunity
IOEIEHHP_02056	2.5e-167	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOEIEHHP_02057	3.75e-104	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOEIEHHP_02059	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOEIEHHP_02060	5.75e-303	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
IOEIEHHP_02061	4e-76	-	-	-	-	-	-	-	-
IOEIEHHP_02062	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOEIEHHP_02063	1.12e-239	tas	-	-	C	-	-	-	Aldo/keto reductase family
IOEIEHHP_02064	3.12e-61	-	-	-	S	-	-	-	Enterocin A Immunity
IOEIEHHP_02065	3.12e-176	-	-	-	-	-	-	-	-
IOEIEHHP_02066	2.03e-178	-	-	-	-	-	-	-	-
IOEIEHHP_02067	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOEIEHHP_02068	2.91e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOEIEHHP_02069	2.52e-265	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IOEIEHHP_02070	2.68e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IOEIEHHP_02071	4.45e-133	-	-	-	-	-	-	-	-
IOEIEHHP_02072	0.0	-	-	-	M	-	-	-	domain protein
IOEIEHHP_02073	0.0	-	-	-	M	-	-	-	domain protein
IOEIEHHP_02074	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
IOEIEHHP_02075	2.19e-184	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOEIEHHP_02076	2.13e-124	-	-	-	-	-	-	-	-
IOEIEHHP_02078	7.14e-192	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOEIEHHP_02079	4.09e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOEIEHHP_02080	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOEIEHHP_02081	4.69e-46	-	-	-	-	-	-	-	-
IOEIEHHP_02082	2.13e-44	-	-	-	-	-	-	-	-
IOEIEHHP_02086	9.49e-26	-	-	-	S	-	-	-	CsbD-like
IOEIEHHP_02087	8.49e-265	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IOEIEHHP_02088	5.45e-61	-	-	-	-	-	-	-	-
IOEIEHHP_02089	1.4e-259	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IOEIEHHP_02090	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOEIEHHP_02091	2.02e-120	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
IOEIEHHP_02092	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
IOEIEHHP_02093	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IOEIEHHP_02094	1.79e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_02095	3.39e-275	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOEIEHHP_02096	4.64e-255	-	-	-	-	-	-	-	-
IOEIEHHP_02097	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOEIEHHP_02098	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IOEIEHHP_02099	5.8e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IOEIEHHP_02100	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
IOEIEHHP_02101	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOEIEHHP_02102	1.06e-258	yacL	-	-	S	-	-	-	domain protein
IOEIEHHP_02103	2.83e-151	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_02104	7.55e-302	inlJ	-	-	M	-	-	-	MucBP domain
IOEIEHHP_02105	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_02106	3.03e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
IOEIEHHP_02107	2.37e-227	-	-	-	S	-	-	-	Membrane
IOEIEHHP_02108	4.13e-190	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IOEIEHHP_02109	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOEIEHHP_02111	1.05e-135	-	-	-	-	-	-	-	-
IOEIEHHP_02112	5.9e-192	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IOEIEHHP_02113	4.53e-133	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IOEIEHHP_02114	1.16e-208	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_02115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOEIEHHP_02116	2.79e-97	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOEIEHHP_02117	5.24e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOEIEHHP_02118	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
IOEIEHHP_02119	7.66e-251	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
IOEIEHHP_02120	5.66e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
IOEIEHHP_02121	1.92e-245	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOEIEHHP_02122	9.72e-53	-	-	-	-	-	-	-	-
IOEIEHHP_02123	7.98e-204	-	-	-	-	-	-	-	-
IOEIEHHP_02124	5.07e-203	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOEIEHHP_02125	3.21e-212	-	-	-	-	-	-	-	-
IOEIEHHP_02126	4.09e-125	-	-	-	-	-	-	-	-
IOEIEHHP_02127	1.2e-196	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOEIEHHP_02128	2.45e-109	-	-	-	-	-	-	-	-
IOEIEHHP_02129	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOEIEHHP_02130	4.01e-125	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
IOEIEHHP_02131	2.87e-106	-	-	-	S	-	-	-	NusG domain II
IOEIEHHP_02132	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOEIEHHP_02133	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
IOEIEHHP_02134	2.67e-295	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IOEIEHHP_02135	2.9e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOEIEHHP_02136	3.19e-212	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IOEIEHHP_02137	1.13e-220	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IOEIEHHP_02138	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOEIEHHP_02139	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOEIEHHP_02140	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOEIEHHP_02141	9.51e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOEIEHHP_02142	9.25e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
IOEIEHHP_02143	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IOEIEHHP_02144	4.11e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IOEIEHHP_02145	4.26e-115	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IOEIEHHP_02146	1.09e-116	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
IOEIEHHP_02147	3.06e-167	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IOEIEHHP_02148	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IOEIEHHP_02149	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOEIEHHP_02150	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOEIEHHP_02151	2.21e-122	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOEIEHHP_02152	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOEIEHHP_02153	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOEIEHHP_02154	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOEIEHHP_02155	1.28e-313	-	-	-	-	-	-	-	-
IOEIEHHP_02156	5.93e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOEIEHHP_02157	3.28e-115	-	-	-	-	-	-	-	-
IOEIEHHP_02158	1.51e-195	-	-	-	K	-	-	-	acetyltransferase
IOEIEHHP_02159	1.04e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IOEIEHHP_02160	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOEIEHHP_02161	4.57e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOEIEHHP_02162	2.29e-199	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOEIEHHP_02163	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOEIEHHP_02164	1.73e-220	ccpB	-	-	K	-	-	-	lacI family
IOEIEHHP_02165	1.92e-88	-	-	-	-	-	-	-	-
IOEIEHHP_02166	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOEIEHHP_02167	9.56e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IOEIEHHP_02168	5.69e-65	-	-	-	-	-	-	-	-
IOEIEHHP_02169	4.22e-112	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOEIEHHP_02170	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOEIEHHP_02171	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOEIEHHP_02172	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOEIEHHP_02173	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IOEIEHHP_02174	3.17e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOEIEHHP_02175	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IOEIEHHP_02176	2.04e-226	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOEIEHHP_02177	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IOEIEHHP_02178	1.33e-195	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOEIEHHP_02179	9.48e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IOEIEHHP_02180	2.5e-231	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IOEIEHHP_02181	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
IOEIEHHP_02182	8.31e-159	-	-	-	-	-	-	-	-
IOEIEHHP_02183	2.21e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IOEIEHHP_02184	8.73e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IOEIEHHP_02185	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOEIEHHP_02186	1.98e-65	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_02187	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IOEIEHHP_02188	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOEIEHHP_02189	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOEIEHHP_02190	1.02e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_02191	6.27e-248	-	-	-	-	-	-	-	-
IOEIEHHP_02193	4.11e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IOEIEHHP_02194	4.3e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOEIEHHP_02195	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOEIEHHP_02196	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOEIEHHP_02197	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IOEIEHHP_02198	0.0	ydaO	-	-	E	-	-	-	amino acid
IOEIEHHP_02199	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOEIEHHP_02200	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOEIEHHP_02201	1.49e-125	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
IOEIEHHP_02202	2.65e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IOEIEHHP_02203	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IOEIEHHP_02204	9.69e-254	-	-	-	I	-	-	-	Acyltransferase
IOEIEHHP_02205	2.58e-183	-	-	-	S	-	-	-	Alpha beta hydrolase
IOEIEHHP_02206	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IOEIEHHP_02207	3.15e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
IOEIEHHP_02208	3.59e-147	-	-	-	F	-	-	-	glutamine amidotransferase
IOEIEHHP_02209	8.9e-139	-	-	-	T	-	-	-	Sh3 type 3 domain protein
IOEIEHHP_02210	5.22e-132	-	-	-	Q	-	-	-	methyltransferase
IOEIEHHP_02212	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOEIEHHP_02213	3.64e-83	-	-	-	-	-	-	-	-
IOEIEHHP_02214	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
IOEIEHHP_02215	7.44e-186	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IOEIEHHP_02216	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
IOEIEHHP_02217	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
IOEIEHHP_02218	6.97e-144	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IOEIEHHP_02219	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
IOEIEHHP_02220	1.57e-34	-	-	-	-	-	-	-	-
IOEIEHHP_02221	5.18e-114	-	-	-	-	-	-	-	-
IOEIEHHP_02222	1.18e-50	-	-	-	-	-	-	-	-
IOEIEHHP_02223	4.63e-230	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOEIEHHP_02224	1.85e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
IOEIEHHP_02225	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IOEIEHHP_02226	4.83e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IOEIEHHP_02227	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IOEIEHHP_02228	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IOEIEHHP_02229	9.16e-230	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
IOEIEHHP_02230	1.28e-97	-	-	-	S	-	-	-	NusG domain II
IOEIEHHP_02231	8.89e-40	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOEIEHHP_02232	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOEIEHHP_02233	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOEIEHHP_02234	2.33e-203	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOEIEHHP_02235	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_02236	1.16e-293	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_02237	1.69e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
IOEIEHHP_02238	6.91e-149	-	-	-	I	-	-	-	ABC-2 family transporter protein
IOEIEHHP_02239	3.59e-206	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_02240	3.94e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOEIEHHP_02241	3.41e-279	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOEIEHHP_02242	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_02243	7.82e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOEIEHHP_02244	9.33e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOEIEHHP_02245	3.55e-205	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IOEIEHHP_02246	2.15e-263	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOEIEHHP_02247	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOEIEHHP_02248	1.09e-60	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	arabinose-5-phosphate isomerase activity
IOEIEHHP_02249	1.86e-107	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOEIEHHP_02250	8.78e-71	-	-	-	M	-	-	-	SIS domain
IOEIEHHP_02251	5.78e-87	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
IOEIEHHP_02252	2.56e-42	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_02253	3.07e-221	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_02254	4.46e-71	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_02255	1.63e-306	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_02256	5.52e-214	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOEIEHHP_02257	3.07e-225	-	-	-	V	ko:K01421	-	ko00000	domain protein
IOEIEHHP_02258	9.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOEIEHHP_02259	4.57e-155	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IOEIEHHP_02260	1.7e-33	-	-	-	E	-	-	-	lactoylglutathione lyase activity
IOEIEHHP_02261	2.12e-273	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOEIEHHP_02262	1.49e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOEIEHHP_02263	6.71e-211	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IOEIEHHP_02264	2.72e-88	-	-	-	-	-	-	-	-
IOEIEHHP_02265	1.16e-284	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
IOEIEHHP_02266	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOEIEHHP_02267	9.26e-290	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IOEIEHHP_02268	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IOEIEHHP_02269	1.02e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOEIEHHP_02270	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IOEIEHHP_02271	3.66e-91	usp1	-	-	T	-	-	-	Universal stress protein family
IOEIEHHP_02272	1.05e-171	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
IOEIEHHP_02273	1.85e-284	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IOEIEHHP_02274	1.23e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOEIEHHP_02275	4.09e-218	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOEIEHHP_02276	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOEIEHHP_02277	4.9e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
IOEIEHHP_02278	2.05e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOEIEHHP_02279	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
IOEIEHHP_02280	6.1e-255	pbpX	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_02281	3.68e-197	-	-	-	S	-	-	-	zinc-ribbon domain
IOEIEHHP_02282	1.98e-40	-	-	-	-	-	-	-	-
IOEIEHHP_02283	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOEIEHHP_02284	1.7e-107	-	-	-	F	-	-	-	NUDIX domain
IOEIEHHP_02285	9.22e-135	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IOEIEHHP_02286	3.44e-236	-	-	-	-	-	-	-	-
IOEIEHHP_02287	3.47e-209	-	-	-	S	-	-	-	Putative esterase
IOEIEHHP_02288	1.6e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOEIEHHP_02289	3.31e-89	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
IOEIEHHP_02290	9.96e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOEIEHHP_02291	4.26e-80	-	-	-	P	-	-	-	Rhodanese-like domain
IOEIEHHP_02292	1.42e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
IOEIEHHP_02293	1.65e-242	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
IOEIEHHP_02294	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IOEIEHHP_02295	4.21e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOEIEHHP_02296	1.67e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOEIEHHP_02297	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOEIEHHP_02298	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
IOEIEHHP_02299	1.46e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IOEIEHHP_02300	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IOEIEHHP_02301	4.91e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOEIEHHP_02302	9.15e-90	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOEIEHHP_02303	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOEIEHHP_02304	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IOEIEHHP_02305	1.45e-192	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOEIEHHP_02306	1.39e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IOEIEHHP_02307	3.95e-297	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IOEIEHHP_02308	7.51e-204	-	-	-	GM	-	-	-	NmrA-like family
IOEIEHHP_02310	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IOEIEHHP_02311	2.55e-224	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOEIEHHP_02312	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOEIEHHP_02313	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_02314	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
IOEIEHHP_02315	2.18e-259	-	-	-	-	-	-	-	-
IOEIEHHP_02317	2.33e-100	-	-	-	-	-	-	-	-
IOEIEHHP_02318	6.81e-13	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IOEIEHHP_02319	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IOEIEHHP_02320	9.6e-253	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IOEIEHHP_02321	3.68e-85	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IOEIEHHP_02322	6.7e-212	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOEIEHHP_02323	1.25e-96	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
IOEIEHHP_02324	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
IOEIEHHP_02325	1.47e-149	-	-	-	-	-	-	-	-
IOEIEHHP_02327	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
IOEIEHHP_02328	7.99e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_02329	3.96e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_02330	1.52e-136	-	-	-	-	-	-	-	-
IOEIEHHP_02331	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
IOEIEHHP_02332	8.66e-173	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
IOEIEHHP_02333	1.01e-171	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IOEIEHHP_02334	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IOEIEHHP_02335	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOEIEHHP_02336	7.54e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOEIEHHP_02337	3.77e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
IOEIEHHP_02338	1.53e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_02339	1.09e-130	-	-	-	-	-	-	-	-
IOEIEHHP_02340	3.29e-188	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
IOEIEHHP_02341	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
IOEIEHHP_02342	1.56e-169	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
IOEIEHHP_02343	5.82e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOEIEHHP_02344	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_02345	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOEIEHHP_02346	1.99e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOEIEHHP_02347	1.17e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOEIEHHP_02348	2.89e-250	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOEIEHHP_02349	7.74e-232	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOEIEHHP_02350	3.43e-148	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
IOEIEHHP_02351	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOEIEHHP_02352	1.73e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
IOEIEHHP_02353	6.57e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IOEIEHHP_02354	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
IOEIEHHP_02355	8.32e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IOEIEHHP_02356	5.16e-164	epsB	-	-	M	-	-	-	biosynthesis protein
IOEIEHHP_02357	3.96e-141	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IOEIEHHP_02358	4.44e-252	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IOEIEHHP_02359	5.78e-181	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IOEIEHHP_02363	5.14e-268	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOEIEHHP_02365	4.04e-27	-	-	-	-	-	-	-	-
IOEIEHHP_02367	2.69e-62	-	-	-	-	-	-	-	-
IOEIEHHP_02368	4.19e-120	XK27_10050	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_02369	1.09e-51	-	-	-	S	-	-	-	sequence-specific DNA binding
IOEIEHHP_02370	1.91e-161	-	-	-	S	-	-	-	DNA binding
IOEIEHHP_02373	1.01e-150	-	-	-	S	-	-	-	ORF6N domain
IOEIEHHP_02378	1.14e-135	-	-	-	S	-	-	-	calcium ion binding
IOEIEHHP_02379	4.28e-292	-	-	-	S	-	-	-	DNA helicase activity
IOEIEHHP_02381	2.13e-46	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IOEIEHHP_02382	1.28e-33	-	-	-	-	-	-	-	-
IOEIEHHP_02383	1.71e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
IOEIEHHP_02385	6.3e-46	-	-	-	-	-	-	-	-
IOEIEHHP_02387	1.49e-77	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
IOEIEHHP_02388	1.35e-50	-	-	-	S	-	-	-	YopX protein
IOEIEHHP_02390	1.28e-65	-	-	-	-	-	-	-	-
IOEIEHHP_02391	2.04e-39	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOEIEHHP_02393	0.000459	-	-	-	S	-	-	-	CsbD-like
IOEIEHHP_02394	9.02e-277	-	-	-	S	-	-	-	GcrA cell cycle regulator
IOEIEHHP_02396	5.08e-85	-	-	-	-	-	-	-	-
IOEIEHHP_02397	1.28e-91	-	-	-	L	-	-	-	HNH nucleases
IOEIEHHP_02398	4.9e-100	-	-	-	S	-	-	-	Phage terminase, small subunit
IOEIEHHP_02399	0.0	-	-	-	S	-	-	-	Phage Terminase
IOEIEHHP_02401	4.6e-274	-	-	-	S	-	-	-	Phage portal protein
IOEIEHHP_02402	3.52e-135	-	-	-	S	-	-	-	peptidase activity
IOEIEHHP_02403	7e-256	-	-	-	S	-	-	-	peptidase activity
IOEIEHHP_02404	8.86e-38	-	-	-	S	-	-	-	peptidase activity
IOEIEHHP_02405	3.09e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOEIEHHP_02406	1.33e-51	-	-	-	S	-	-	-	Phage head-tail joining protein
IOEIEHHP_02407	1.39e-88	-	-	-	S	-	-	-	exonuclease activity
IOEIEHHP_02408	1.87e-38	-	-	-	-	-	-	-	-
IOEIEHHP_02409	4.84e-94	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
IOEIEHHP_02410	1.09e-26	-	-	-	-	-	-	-	-
IOEIEHHP_02411	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
IOEIEHHP_02412	3.48e-296	-	-	-	S	-	-	-	Phage tail protein
IOEIEHHP_02413	0.0	-	-	-	S	-	-	-	cellulase activity
IOEIEHHP_02414	1.16e-64	-	-	-	-	-	-	-	-
IOEIEHHP_02416	4.55e-60	-	-	-	-	-	-	-	-
IOEIEHHP_02417	3.43e-85	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
IOEIEHHP_02418	3.85e-278	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOEIEHHP_02420	4.08e-138	-	-	-	-	-	-	-	-
IOEIEHHP_02421	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOEIEHHP_02422	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
IOEIEHHP_02423	1.97e-106	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IOEIEHHP_02424	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IOEIEHHP_02425	1.3e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IOEIEHHP_02426	1.49e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IOEIEHHP_02427	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOEIEHHP_02428	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IOEIEHHP_02429	5.43e-166	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOEIEHHP_02430	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IOEIEHHP_02431	2.15e-176	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOEIEHHP_02432	1.09e-122	-	-	-	F	-	-	-	NUDIX domain
IOEIEHHP_02434	2.8e-111	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IOEIEHHP_02435	1.82e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IOEIEHHP_02436	1.27e-279	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOEIEHHP_02437	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IOEIEHHP_02438	3.14e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IOEIEHHP_02439	3.45e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IOEIEHHP_02440	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
IOEIEHHP_02441	3.46e-136	-	-	-	S	-	-	-	CYTH
IOEIEHHP_02442	4.15e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IOEIEHHP_02443	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOEIEHHP_02444	8.25e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOEIEHHP_02445	2.81e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOEIEHHP_02446	3.56e-143	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IOEIEHHP_02447	4.82e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOEIEHHP_02448	1.81e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IOEIEHHP_02449	2.53e-80	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IOEIEHHP_02450	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOEIEHHP_02451	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOEIEHHP_02452	2.76e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOEIEHHP_02453	1.34e-197	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IOEIEHHP_02454	7.57e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOEIEHHP_02455	8.84e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IOEIEHHP_02456	1.5e-14	-	-	-	-	-	-	-	-
IOEIEHHP_02457	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOEIEHHP_02458	7.4e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IOEIEHHP_02459	1.87e-307	ymfH	-	-	S	-	-	-	Peptidase M16
IOEIEHHP_02460	1.22e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IOEIEHHP_02461	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IOEIEHHP_02462	7.88e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOEIEHHP_02463	5.58e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOEIEHHP_02464	9.49e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOEIEHHP_02465	1.91e-16	-	-	-	-	-	-	-	-
IOEIEHHP_02466	1.75e-21	-	-	-	-	-	-	-	-
IOEIEHHP_02467	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IOEIEHHP_02468	7.45e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IOEIEHHP_02469	1.06e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IOEIEHHP_02470	5.17e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IOEIEHHP_02471	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOEIEHHP_02472	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOEIEHHP_02473	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOEIEHHP_02474	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
IOEIEHHP_02475	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOEIEHHP_02476	5.6e-251	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IOEIEHHP_02477	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOEIEHHP_02478	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOEIEHHP_02479	5.25e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOEIEHHP_02480	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOEIEHHP_02481	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IOEIEHHP_02482	6.38e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOEIEHHP_02483	1.44e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOEIEHHP_02484	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IOEIEHHP_02485	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
IOEIEHHP_02486	3.47e-49	-	-	-	-	-	-	-	-
IOEIEHHP_02487	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IOEIEHHP_02488	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOEIEHHP_02489	2.43e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOEIEHHP_02490	2.2e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IOEIEHHP_02491	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOEIEHHP_02492	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOEIEHHP_02493	1.03e-107	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOEIEHHP_02494	3.28e-143	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IOEIEHHP_02495	4.02e-116	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_02496	2.31e-299	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOEIEHHP_02497	2.71e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IOEIEHHP_02498	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOEIEHHP_02499	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOEIEHHP_02500	2.45e-109	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOEIEHHP_02501	1.21e-212	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOEIEHHP_02502	2.87e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IOEIEHHP_02503	2.36e-199	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOEIEHHP_02504	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IOEIEHHP_02505	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOEIEHHP_02507	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IOEIEHHP_02508	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOEIEHHP_02509	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IOEIEHHP_02510	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOEIEHHP_02511	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOEIEHHP_02512	2.63e-82	-	-	-	-	-	-	-	-
IOEIEHHP_02514	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IOEIEHHP_02515	3.49e-77	-	-	-	-	-	-	-	-
IOEIEHHP_02516	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IOEIEHHP_02517	3.69e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
IOEIEHHP_02518	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOEIEHHP_02519	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOEIEHHP_02520	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOEIEHHP_02521	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IOEIEHHP_02522	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
IOEIEHHP_02523	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOEIEHHP_02524	6.41e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IOEIEHHP_02525	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
IOEIEHHP_02526	3.54e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IOEIEHHP_02527	1.03e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IOEIEHHP_02528	3.69e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOEIEHHP_02529	2.96e-144	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IOEIEHHP_02530	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOEIEHHP_02531	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOEIEHHP_02532	6.9e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IOEIEHHP_02533	1.63e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IOEIEHHP_02534	3.48e-73	-	-	-	-	-	-	-	-
IOEIEHHP_02535	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOEIEHHP_02536	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IOEIEHHP_02537	3.4e-173	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOEIEHHP_02538	1.51e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOEIEHHP_02539	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
IOEIEHHP_02540	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IOEIEHHP_02541	1.27e-273	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOEIEHHP_02542	4.48e-120	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
IOEIEHHP_02543	1.93e-100	ytxH	-	-	S	-	-	-	YtxH-like protein
IOEIEHHP_02544	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOEIEHHP_02546	2.14e-201	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IOEIEHHP_02547	6.86e-201	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
IOEIEHHP_02548	5.39e-111	ykuL	-	-	S	-	-	-	CBS domain
IOEIEHHP_02549	2.59e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
IOEIEHHP_02550	6.42e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IOEIEHHP_02551	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOEIEHHP_02552	4.8e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IOEIEHHP_02553	3.64e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOEIEHHP_02554	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOEIEHHP_02555	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IOEIEHHP_02556	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOEIEHHP_02557	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOEIEHHP_02558	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOEIEHHP_02559	3.15e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
IOEIEHHP_02560	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOEIEHHP_02561	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IOEIEHHP_02562	3.79e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOEIEHHP_02563	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IOEIEHHP_02564	1.42e-266	-	-	-	-	-	-	-	-
IOEIEHHP_02565	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOEIEHHP_02566	1.42e-219	-	-	-	-	-	-	-	-
IOEIEHHP_02567	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOEIEHHP_02568	3.39e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IOEIEHHP_02569	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
IOEIEHHP_02570	2.53e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOEIEHHP_02571	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOEIEHHP_02572	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
IOEIEHHP_02573	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IOEIEHHP_02574	2.9e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IOEIEHHP_02575	2e-288	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOEIEHHP_02576	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOEIEHHP_02577	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOEIEHHP_02578	2.42e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOEIEHHP_02579	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
IOEIEHHP_02580	1.39e-111	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOEIEHHP_02581	6.91e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IOEIEHHP_02582	3.04e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IOEIEHHP_02583	1.29e-149	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOEIEHHP_02584	4.04e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
IOEIEHHP_02585	3.71e-161	-	-	-	-	-	-	-	-
IOEIEHHP_02586	3.19e-202	dkgB	-	-	S	-	-	-	reductase
IOEIEHHP_02587	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IOEIEHHP_02588	6.89e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IOEIEHHP_02589	2.15e-99	-	-	-	K	-	-	-	Transcriptional regulator
IOEIEHHP_02590	2.61e-155	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IOEIEHHP_02591	9.32e-255	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOEIEHHP_02592	2.15e-121	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOEIEHHP_02593	1.03e-77	-	-	-	-	-	-	-	-
IOEIEHHP_02594	8.32e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOEIEHHP_02595	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IOEIEHHP_02596	1.91e-78	-	-	-	-	-	-	-	-
IOEIEHHP_02597	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IOEIEHHP_02598	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
IOEIEHHP_02599	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_02600	1.42e-221	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_02601	2.68e-31	-	-	-	-	-	-	-	-
IOEIEHHP_02602	2.23e-81	-	-	-	-	-	-	-	-
IOEIEHHP_02603	4.58e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOEIEHHP_02604	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IOEIEHHP_02605	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IOEIEHHP_02606	1.4e-205	mleR	-	-	K	-	-	-	LysR family
IOEIEHHP_02607	2.46e-220	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOEIEHHP_02608	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IOEIEHHP_02609	5.82e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOEIEHHP_02610	3.78e-158	-	-	-	-	-	-	-	-
IOEIEHHP_02611	1.1e-136	-	-	-	S	-	-	-	Flavin reductase like domain
IOEIEHHP_02612	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IOEIEHHP_02613	7.69e-100	-	-	-	-	-	-	-	-
IOEIEHHP_02614	2.46e-130	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOEIEHHP_02615	1.99e-36	-	-	-	-	-	-	-	-
IOEIEHHP_02616	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IOEIEHHP_02617	6.82e-104	-	-	-	-	-	-	-	-
IOEIEHHP_02618	2.38e-74	-	-	-	-	-	-	-	-
IOEIEHHP_02619	3.18e-238	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOEIEHHP_02620	1.46e-65	-	-	-	-	-	-	-	-
IOEIEHHP_02621	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IOEIEHHP_02622	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOEIEHHP_02623	7.49e-196	-	-	-	K	-	-	-	sequence-specific DNA binding
IOEIEHHP_02627	2.15e-261	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
IOEIEHHP_02628	3.43e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
IOEIEHHP_02629	1.35e-85	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IOEIEHHP_02630	1.08e-306	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IOEIEHHP_02631	4.31e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
IOEIEHHP_02632	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
IOEIEHHP_02633	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IOEIEHHP_02634	9.42e-232	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
IOEIEHHP_02635	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOEIEHHP_02636	6.23e-218	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOEIEHHP_02637	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_02638	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOEIEHHP_02639	3.97e-212	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_02641	2.16e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IOEIEHHP_02642	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IOEIEHHP_02644	3.69e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
IOEIEHHP_02646	4.63e-253	-	-	-	-	-	-	-	-
IOEIEHHP_02647	1.35e-196	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOEIEHHP_02648	1.56e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOEIEHHP_02650	2.02e-154	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IOEIEHHP_02651	6.41e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOEIEHHP_02652	3.94e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
IOEIEHHP_02653	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOEIEHHP_02654	4.79e-21	-	-	-	-	-	-	-	-
IOEIEHHP_02655	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IOEIEHHP_02656	1.85e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOEIEHHP_02657	2.74e-77	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IOEIEHHP_02664	1.03e-16	amfT	-	-	KLT	-	-	-	serine threonine protein kinase
IOEIEHHP_02666	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOEIEHHP_02668	6.32e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOEIEHHP_02669	3.42e-167	ydfF	-	-	K	-	-	-	Transcriptional
IOEIEHHP_02670	3e-171	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_02671	1.88e-175	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IOEIEHHP_02672	1.23e-226	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
IOEIEHHP_02673	7.39e-188	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IOEIEHHP_02674	0.0	-	-	-	L	-	-	-	DNA helicase
IOEIEHHP_02675	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOEIEHHP_02676	2.58e-226	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_02677	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IOEIEHHP_02678	5.17e-82	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOEIEHHP_02679	4.94e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOEIEHHP_02680	5.07e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IOEIEHHP_02681	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IOEIEHHP_02682	3.21e-303	dinF	-	-	V	-	-	-	MatE
IOEIEHHP_02683	2.66e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IOEIEHHP_02684	5.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IOEIEHHP_02685	1.43e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
IOEIEHHP_02686	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IOEIEHHP_02687	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOEIEHHP_02688	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IOEIEHHP_02689	4.92e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IOEIEHHP_02690	1.32e-51	-	-	-	-	-	-	-	-
IOEIEHHP_02691	2.75e-62	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IOEIEHHP_02692	4.22e-215	-	-	-	-	-	-	-	-
IOEIEHHP_02693	1.29e-23	-	-	-	-	-	-	-	-
IOEIEHHP_02694	1.14e-164	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOEIEHHP_02695	5.76e-140	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOEIEHHP_02696	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IOEIEHHP_02697	1.28e-117	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOEIEHHP_02698	2.82e-194	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IOEIEHHP_02700	7.4e-222	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOEIEHHP_02701	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOEIEHHP_02702	6.92e-85	-	-	-	-	-	-	-	-
IOEIEHHP_02703	5.39e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IOEIEHHP_02704	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOEIEHHP_02705	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOEIEHHP_02706	5.78e-215	-	-	-	T	-	-	-	GHKL domain
IOEIEHHP_02707	5e-161	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOEIEHHP_02708	8.61e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
IOEIEHHP_02709	3.72e-237	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
IOEIEHHP_02710	2.64e-103	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IOEIEHHP_02711	2.14e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IOEIEHHP_02712	2.76e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOEIEHHP_02713	1.14e-196	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOEIEHHP_02714	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IOEIEHHP_02715	6.22e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOEIEHHP_02716	6.67e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IOEIEHHP_02717	2.5e-159	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IOEIEHHP_02718	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_02719	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IOEIEHHP_02720	8.74e-280	ysaA	-	-	V	-	-	-	RDD family
IOEIEHHP_02721	1.05e-295	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOEIEHHP_02722	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOEIEHHP_02723	9.05e-67	nudA	-	-	S	-	-	-	ASCH
IOEIEHHP_02724	1.36e-47	-	-	-	-	-	-	-	-
IOEIEHHP_02725	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOEIEHHP_02726	4.14e-235	-	-	-	S	-	-	-	DUF218 domain
IOEIEHHP_02727	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOEIEHHP_02728	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IOEIEHHP_02729	1.63e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
IOEIEHHP_02730	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IOEIEHHP_02731	1.09e-102	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOEIEHHP_02732	2.12e-195	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOEIEHHP_02735	9.47e-281	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOEIEHHP_02736	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOEIEHHP_02737	6.15e-06	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOEIEHHP_02738	1.99e-19	-	-	-	-	-	-	-	-
IOEIEHHP_02739	3.31e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOEIEHHP_02740	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IOEIEHHP_02741	2.21e-94	-	-	-	-	-	-	-	-
IOEIEHHP_02742	2.22e-159	-	-	-	-	-	-	-	-
IOEIEHHP_02743	6.44e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOEIEHHP_02744	8.77e-190	-	-	-	-	-	-	-	-
IOEIEHHP_02745	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOEIEHHP_02746	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOEIEHHP_02747	4.55e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOEIEHHP_02748	1.68e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOEIEHHP_02749	5.46e-51	-	-	-	-	-	-	-	-
IOEIEHHP_02750	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IOEIEHHP_02751	5.65e-113	queT	-	-	S	-	-	-	QueT transporter
IOEIEHHP_02752	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
IOEIEHHP_02753	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOEIEHHP_02754	2.4e-167	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IOEIEHHP_02755	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
IOEIEHHP_02756	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
IOEIEHHP_02757	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
IOEIEHHP_02758	6.37e-125	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOEIEHHP_02759	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IOEIEHHP_02760	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOEIEHHP_02761	2.48e-130	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOEIEHHP_02762	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOEIEHHP_02763	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IOEIEHHP_02764	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
IOEIEHHP_02765	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
IOEIEHHP_02766	3.52e-106	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IOEIEHHP_02767	6.09e-311	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOEIEHHP_02768	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOEIEHHP_02769	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOEIEHHP_02771	1.71e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOEIEHHP_02772	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOEIEHHP_02773	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOEIEHHP_02774	8.37e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IOEIEHHP_02775	3.35e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_02776	4.28e-173	-	-	-	-	-	-	-	-
IOEIEHHP_02777	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOEIEHHP_02778	1.12e-84	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_02779	4.11e-229	-	-	-	S	-	-	-	Cell surface protein
IOEIEHHP_02780	9.71e-64	-	-	-	-	-	-	-	-
IOEIEHHP_02781	8.95e-302	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IOEIEHHP_02783	3.52e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_02784	3.6e-80	-	-	-	-	-	-	-	-
IOEIEHHP_02785	4.1e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
IOEIEHHP_02786	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IOEIEHHP_02787	3.1e-214	yicL	-	-	EG	-	-	-	EamA-like transporter family
IOEIEHHP_02788	0.0	-	-	-	-	-	-	-	-
IOEIEHHP_02789	7.71e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOEIEHHP_02790	2.58e-101	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IOEIEHHP_02791	3.39e-188	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IOEIEHHP_02792	2.64e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IOEIEHHP_02793	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOEIEHHP_02794	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOEIEHHP_02795	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_02796	8.8e-283	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IOEIEHHP_02797	6.34e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IOEIEHHP_02798	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOEIEHHP_02799	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOEIEHHP_02800	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IOEIEHHP_02801	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IOEIEHHP_02802	2.66e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
IOEIEHHP_02803	4.65e-316	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOEIEHHP_02804	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOEIEHHP_02805	2.9e-90	-	-	-	-	-	-	-	-
IOEIEHHP_02806	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
IOEIEHHP_02807	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IOEIEHHP_02808	1.11e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IOEIEHHP_02809	2.06e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
IOEIEHHP_02810	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IOEIEHHP_02811	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
IOEIEHHP_02812	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IOEIEHHP_02813	4.03e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IOEIEHHP_02814	5.63e-12	-	-	-	K	-	-	-	LytTr DNA-binding domain
IOEIEHHP_02815	6.56e-193	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IOEIEHHP_02816	4.47e-200	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOEIEHHP_02817	1.34e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOEIEHHP_02818	1.83e-148	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IOEIEHHP_02819	1.24e-68	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IOEIEHHP_02820	6.99e-120	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
IOEIEHHP_02821	4.29e-201	-	-	-	C	-	-	-	nadph quinone reductase
IOEIEHHP_02822	5.42e-311	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IOEIEHHP_02823	1.97e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IOEIEHHP_02824	2.22e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IOEIEHHP_02825	6.15e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IOEIEHHP_02827	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IOEIEHHP_02828	6.84e-301	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
IOEIEHHP_02829	5.13e-37	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
IOEIEHHP_02830	8.94e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IOEIEHHP_02831	2.82e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOEIEHHP_02832	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
IOEIEHHP_02833	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOEIEHHP_02834	1.09e-168	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
IOEIEHHP_02836	1.47e-176	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
IOEIEHHP_02837	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
IOEIEHHP_02838	1.89e-311	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOEIEHHP_02839	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOEIEHHP_02840	1.64e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOEIEHHP_02841	1.04e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOEIEHHP_02842	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOEIEHHP_02843	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOEIEHHP_02844	7.62e-248	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IOEIEHHP_02846	4.46e-91	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOEIEHHP_02847	2.13e-64	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOEIEHHP_02848	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOEIEHHP_02850	1.91e-38	-	-	-	-	-	-	-	-
IOEIEHHP_02851	3.71e-237	-	-	-	V	-	-	-	Beta-lactamase
IOEIEHHP_02852	9.05e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
IOEIEHHP_02853	1.43e-224	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOEIEHHP_02854	1.71e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
IOEIEHHP_02855	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IOEIEHHP_02856	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IOEIEHHP_02857	2.49e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IOEIEHHP_02858	2.08e-63	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant