Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PFLHLHFN_00001	1.44e-62	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PFLHLHFN_00002	1.64e-169	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PFLHLHFN_00003	8.27e-88	-	-	-	GM	-	-	-	NAD(P)H-binding
PFLHLHFN_00004	1.59e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
PFLHLHFN_00005	3.49e-113	-	-	-	K	-	-	-	LysR substrate binding domain
PFLHLHFN_00007	2.25e-57	-	-	-	K	-	-	-	Tetracycline repressor, C-terminal all-alpha domain
PFLHLHFN_00008	5.94e-100	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
PFLHLHFN_00010	4.85e-93	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PFLHLHFN_00011	1.91e-28	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PFLHLHFN_00012	1.52e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
PFLHLHFN_00013	2.53e-287	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00015	2.77e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PFLHLHFN_00016	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFLHLHFN_00017	1.44e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PFLHLHFN_00018	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PFLHLHFN_00019	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PFLHLHFN_00020	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PFLHLHFN_00021	7.25e-309	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PFLHLHFN_00022	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFLHLHFN_00023	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
PFLHLHFN_00024	1.5e-90	-	-	-	-	-	-	-	-
PFLHLHFN_00025	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PFLHLHFN_00026	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PFLHLHFN_00027	3.19e-165	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PFLHLHFN_00028	6.44e-200	epsV	-	-	S	-	-	-	glycosyl transferase family 2
PFLHLHFN_00029	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PFLHLHFN_00030	1.46e-189	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFLHLHFN_00031	1.51e-233	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PFLHLHFN_00032	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFLHLHFN_00033	2.29e-112	-	-	-	-	-	-	-	-
PFLHLHFN_00034	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PFLHLHFN_00035	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PFLHLHFN_00036	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_00037	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
PFLHLHFN_00038	2.18e-122	yneE	-	-	K	-	-	-	Transcriptional regulator
PFLHLHFN_00039	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PFLHLHFN_00040	5.05e-11	-	-	-	-	-	-	-	-
PFLHLHFN_00041	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
PFLHLHFN_00043	7.68e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFLHLHFN_00045	4e-79	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PFLHLHFN_00046	4.52e-178	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_00047	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PFLHLHFN_00048	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
PFLHLHFN_00049	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
PFLHLHFN_00050	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PFLHLHFN_00051	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00052	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00053	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFLHLHFN_00054	3.87e-73	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PFLHLHFN_00055	4.66e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFLHLHFN_00056	1.19e-43	-	-	-	S	-	-	-	reductase
PFLHLHFN_00057	2.98e-50	-	-	-	S	-	-	-	reductase
PFLHLHFN_00058	1.26e-40	-	-	-	S	-	-	-	reductase
PFLHLHFN_00059	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
PFLHLHFN_00060	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFLHLHFN_00061	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PFLHLHFN_00062	1.99e-22	-	-	-	E	-	-	-	Pfam:DUF955
PFLHLHFN_00063	4.53e-143	-	-	-	S	-	-	-	Fic/DOC family
PFLHLHFN_00064	2.13e-23	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PFLHLHFN_00065	1.02e-34	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PFLHLHFN_00068	1.21e-209	lprD	-	-	V	ko:K02005,ko:K02022	-	ko00000	PFAM secretion protein HlyD family protein
PFLHLHFN_00069	1.5e-27	-	-	-	S	-	-	-	Enterocin A Immunity
PFLHLHFN_00071	1.23e-54	-	-	-	V	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
PFLHLHFN_00072	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PFLHLHFN_00073	1.64e-101	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PFLHLHFN_00074	1.79e-99	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PFLHLHFN_00075	3.09e-71	-	-	-	-	-	-	-	-
PFLHLHFN_00076	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PFLHLHFN_00077	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PFLHLHFN_00078	4.52e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PFLHLHFN_00079	4.31e-175	-	-	-	-	-	-	-	-
PFLHLHFN_00080	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PFLHLHFN_00081	2.36e-12	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
PFLHLHFN_00082	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
PFLHLHFN_00086	8.04e-143	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PFLHLHFN_00087	5.71e-230	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PFLHLHFN_00088	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PFLHLHFN_00089	1.24e-188	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
PFLHLHFN_00090	3.43e-79	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
PFLHLHFN_00091	3.61e-60	-	-	-	-	-	-	-	-
PFLHLHFN_00092	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PFLHLHFN_00094	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_00095	6.55e-97	-	-	-	-	-	-	-	-
PFLHLHFN_00096	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PFLHLHFN_00101	2.38e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
PFLHLHFN_00102	7.62e-41	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_00103	4.74e-30	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
PFLHLHFN_00104	6.66e-31	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_00106	2.63e-194	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_00107	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PFLHLHFN_00108	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PFLHLHFN_00109	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFLHLHFN_00112	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PFLHLHFN_00113	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PFLHLHFN_00114	6.45e-291	-	-	-	E	-	-	-	amino acid
PFLHLHFN_00115	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PFLHLHFN_00117	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
PFLHLHFN_00118	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_00119	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PFLHLHFN_00120	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PFLHLHFN_00121	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PFLHLHFN_00122	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
PFLHLHFN_00123	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PFLHLHFN_00124	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00125	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00126	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00127	1.96e-49	-	-	-	-	-	-	-	-
PFLHLHFN_00128	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PFLHLHFN_00129	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFLHLHFN_00130	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PFLHLHFN_00131	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_00132	9.71e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFLHLHFN_00133	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFLHLHFN_00134	3.08e-306	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PFLHLHFN_00135	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFLHLHFN_00136	9.18e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PFLHLHFN_00137	1.42e-58	-	-	-	-	-	-	-	-
PFLHLHFN_00138	5.11e-265	-	-	-	S	-	-	-	Membrane
PFLHLHFN_00139	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
PFLHLHFN_00140	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PFLHLHFN_00141	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
PFLHLHFN_00142	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PFLHLHFN_00143	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
PFLHLHFN_00144	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PFLHLHFN_00145	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_00146	1.05e-67	-	-	-	-	-	-	-	-
PFLHLHFN_00147	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PFLHLHFN_00148	1.49e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
PFLHLHFN_00149	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PFLHLHFN_00150	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
PFLHLHFN_00151	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00152	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PFLHLHFN_00153	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PFLHLHFN_00154	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PFLHLHFN_00155	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PFLHLHFN_00156	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PFLHLHFN_00157	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PFLHLHFN_00158	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PFLHLHFN_00159	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
PFLHLHFN_00160	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PFLHLHFN_00161	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PFLHLHFN_00162	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PFLHLHFN_00163	6.64e-94	-	-	-	-	-	-	-	-
PFLHLHFN_00164	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PFLHLHFN_00165	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PFLHLHFN_00166	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
PFLHLHFN_00167	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
PFLHLHFN_00170	5.43e-63	-	-	-	D	-	-	-	Plasmid recombination enzyme
PFLHLHFN_00172	4.14e-133	-	-	-	L	-	-	-	Initiator Replication protein
PFLHLHFN_00173	4.29e-137	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PFLHLHFN_00174	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PFLHLHFN_00175	3.46e-32	-	-	-	S	-	-	-	Alpha beta hydrolase
PFLHLHFN_00176	1.47e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PFLHLHFN_00177	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PFLHLHFN_00179	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00180	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PFLHLHFN_00181	2.16e-79	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFLHLHFN_00182	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFLHLHFN_00183	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PFLHLHFN_00184	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PFLHLHFN_00185	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PFLHLHFN_00186	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PFLHLHFN_00187	2.43e-196	-	-	-	I	-	-	-	Alpha/beta hydrolase family
PFLHLHFN_00188	2.09e-105	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PFLHLHFN_00189	1.91e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PFLHLHFN_00190	3.09e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PFLHLHFN_00191	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PFLHLHFN_00192	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFLHLHFN_00194	3.54e-94	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
PFLHLHFN_00195	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PFLHLHFN_00196	2.06e-111	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
PFLHLHFN_00197	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
PFLHLHFN_00198	4.49e-108	-	-	-	-	-	-	-	-
PFLHLHFN_00199	1.83e-54	-	-	-	C	-	-	-	FMN_bind
PFLHLHFN_00200	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PFLHLHFN_00201	7.73e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PFLHLHFN_00202	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PFLHLHFN_00203	5.01e-150	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PFLHLHFN_00204	7.68e-63	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PFLHLHFN_00205	1.43e-309	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PFLHLHFN_00206	0.0	-	-	-	L	-	-	-	PLD-like domain
PFLHLHFN_00207	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
PFLHLHFN_00208	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
PFLHLHFN_00209	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
PFLHLHFN_00210	5.51e-35	-	-	-	-	-	-	-	-
PFLHLHFN_00212	4.36e-46	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
PFLHLHFN_00213	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
PFLHLHFN_00214	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PFLHLHFN_00215	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PFLHLHFN_00216	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PFLHLHFN_00217	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PFLHLHFN_00218	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PFLHLHFN_00219	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PFLHLHFN_00220	9.48e-31	-	-	-	-	-	-	-	-
PFLHLHFN_00221	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFLHLHFN_00222	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
PFLHLHFN_00223	2.24e-162	-	-	-	L	-	-	-	Transposase and inactivated derivatives
PFLHLHFN_00224	5.6e-133	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PFLHLHFN_00225	1.31e-245	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PFLHLHFN_00226	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PFLHLHFN_00227	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PFLHLHFN_00228	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PFLHLHFN_00229	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PFLHLHFN_00230	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PFLHLHFN_00231	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PFLHLHFN_00232	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PFLHLHFN_00233	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PFLHLHFN_00234	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PFLHLHFN_00235	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PFLHLHFN_00236	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PFLHLHFN_00237	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PFLHLHFN_00238	5.57e-107	-	-	-	M	-	-	-	family 8
PFLHLHFN_00239	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFLHLHFN_00240	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PFLHLHFN_00241	6.15e-36	-	-	-	-	-	-	-	-
PFLHLHFN_00242	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PFLHLHFN_00243	3.64e-188	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
PFLHLHFN_00244	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PFLHLHFN_00245	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PFLHLHFN_00247	1.61e-117	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_00248	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PFLHLHFN_00249	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFLHLHFN_00250	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFLHLHFN_00251	2.48e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PFLHLHFN_00252	1.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PFLHLHFN_00253	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PFLHLHFN_00254	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PFLHLHFN_00255	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PFLHLHFN_00256	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PFLHLHFN_00257	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PFLHLHFN_00258	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PFLHLHFN_00259	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PFLHLHFN_00260	1.19e-45	-	-	-	-	-	-	-	-
PFLHLHFN_00261	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
PFLHLHFN_00262	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFLHLHFN_00263	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PFLHLHFN_00264	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PFLHLHFN_00265	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PFLHLHFN_00266	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PFLHLHFN_00267	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PFLHLHFN_00268	4.51e-69	-	-	-	-	-	-	-	-
PFLHLHFN_00269	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PFLHLHFN_00270	2.13e-66	-	-	-	-	-	-	-	-
PFLHLHFN_00271	2.32e-234	-	-	-	S	-	-	-	AAA domain
PFLHLHFN_00272	9.82e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFLHLHFN_00273	2.42e-33	-	-	-	-	-	-	-	-
PFLHLHFN_00274	5.08e-207	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PFLHLHFN_00275	1.34e-161	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PFLHLHFN_00276	7.36e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PFLHLHFN_00277	2.7e-153	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PFLHLHFN_00278	2.64e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PFLHLHFN_00279	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PFLHLHFN_00280	4.4e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
PFLHLHFN_00282	8.71e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PFLHLHFN_00283	1.21e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_00284	7.51e-16	-	-	-	L	-	-	-	Transposase
PFLHLHFN_00285	1.01e-22	-	-	-	L	-	-	-	Transposase
PFLHLHFN_00286	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PFLHLHFN_00287	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
PFLHLHFN_00288	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PFLHLHFN_00289	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
PFLHLHFN_00290	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
PFLHLHFN_00291	1.13e-40	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PFLHLHFN_00292	1.97e-294	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PFLHLHFN_00293	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_00294	2.58e-220	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
PFLHLHFN_00295	6.76e-101	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
PFLHLHFN_00296	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
PFLHLHFN_00297	4.63e-32	-	-	-	-	-	-	-	-
PFLHLHFN_00298	5.49e-222	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
PFLHLHFN_00299	3.77e-68	-	-	-	-	-	-	-	-
PFLHLHFN_00300	3.6e-81	-	-	-	CO	-	-	-	Thioredoxin
PFLHLHFN_00301	3.19e-120	-	-	-	-	-	-	-	-
PFLHLHFN_00302	9.67e-311	-	-	-	NU	-	-	-	CHAP domain
PFLHLHFN_00303	6.37e-74	-	-	-	M	-	-	-	Cell wall surface anchor family protein
PFLHLHFN_00304	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
PFLHLHFN_00305	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PFLHLHFN_00306	1.02e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PFLHLHFN_00307	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_00308	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PFLHLHFN_00309	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PFLHLHFN_00310	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PFLHLHFN_00311	1.86e-91	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_00312	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_00313	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PFLHLHFN_00314	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PFLHLHFN_00315	1.94e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
PFLHLHFN_00316	2.36e-217	degV1	-	-	S	-	-	-	DegV family
PFLHLHFN_00317	7.09e-172	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_00318	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00319	1.73e-79	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PFLHLHFN_00320	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PFLHLHFN_00321	1.32e-171	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFLHLHFN_00322	8.83e-170	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PFLHLHFN_00323	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PFLHLHFN_00324	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PFLHLHFN_00325	1.12e-28	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
PFLHLHFN_00326	1.74e-33	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_00328	9.22e-113	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_00332	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PFLHLHFN_00333	2.47e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PFLHLHFN_00334	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PFLHLHFN_00335	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PFLHLHFN_00336	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
PFLHLHFN_00337	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_00338	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PFLHLHFN_00339	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PFLHLHFN_00340	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_00345	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_00346	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFLHLHFN_00347	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_00348	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PFLHLHFN_00349	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PFLHLHFN_00350	1.46e-75	-	-	-	-	-	-	-	-
PFLHLHFN_00351	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PFLHLHFN_00352	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PFLHLHFN_00353	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFLHLHFN_00354	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PFLHLHFN_00355	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFLHLHFN_00356	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
PFLHLHFN_00357	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PFLHLHFN_00358	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PFLHLHFN_00359	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PFLHLHFN_00361	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PFLHLHFN_00362	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PFLHLHFN_00363	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PFLHLHFN_00364	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PFLHLHFN_00365	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PFLHLHFN_00366	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PFLHLHFN_00367	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PFLHLHFN_00368	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFLHLHFN_00369	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
PFLHLHFN_00370	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PFLHLHFN_00371	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
PFLHLHFN_00372	9.75e-163	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PFLHLHFN_00373	2.17e-232	-	-	-	-	-	-	-	-
PFLHLHFN_00374	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00375	7.83e-303	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00378	7.62e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PFLHLHFN_00379	1.48e-14	-	-	-	-	-	-	-	-
PFLHLHFN_00380	5.24e-31	-	-	-	S	-	-	-	transposase or invertase
PFLHLHFN_00381	9.6e-309	slpX	-	-	S	-	-	-	SLAP domain
PFLHLHFN_00382	1.43e-186	-	-	-	K	-	-	-	SIS domain
PFLHLHFN_00383	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PFLHLHFN_00384	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PFLHLHFN_00385	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFLHLHFN_00387	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PFLHLHFN_00389	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PFLHLHFN_00390	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PFLHLHFN_00391	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
PFLHLHFN_00392	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PFLHLHFN_00393	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
PFLHLHFN_00394	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
PFLHLHFN_00395	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00396	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00397	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_00398	1.25e-17	-	-	-	-	-	-	-	-
PFLHLHFN_00399	2.77e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
PFLHLHFN_00400	1.04e-41	-	-	-	-	-	-	-	-
PFLHLHFN_00402	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PFLHLHFN_00403	4.53e-11	-	-	-	-	-	-	-	-
PFLHLHFN_00404	1.02e-75	-	-	-	-	-	-	-	-
PFLHLHFN_00405	2.62e-69	-	-	-	-	-	-	-	-
PFLHLHFN_00407	4.4e-165	-	-	-	S	-	-	-	PAS domain
PFLHLHFN_00408	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PFLHLHFN_00409	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PFLHLHFN_00410	4.36e-27	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PFLHLHFN_00411	5.76e-292	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PFLHLHFN_00412	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PFLHLHFN_00413	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PFLHLHFN_00414	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PFLHLHFN_00415	1.64e-45	-	-	-	-	-	-	-	-
PFLHLHFN_00416	8.08e-117	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00417	1.02e-67	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00418	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00419	4.11e-150	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00420	1.8e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
PFLHLHFN_00421	1.8e-36	-	-	-	M	-	-	-	LysM domain protein
PFLHLHFN_00422	9.44e-63	-	-	-	M	-	-	-	LysM domain protein
PFLHLHFN_00423	9.11e-110	-	-	-	C	-	-	-	Aldo keto reductase
PFLHLHFN_00424	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PFLHLHFN_00425	2.86e-169	-	-	-	L	-	-	-	Transposase and inactivated derivatives
PFLHLHFN_00427	3.31e-65	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PFLHLHFN_00431	8.34e-116	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00432	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PFLHLHFN_00433	1.1e-96	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PFLHLHFN_00434	1.91e-233	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PFLHLHFN_00435	8.77e-189	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
PFLHLHFN_00437	1.28e-162	sagD	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
PFLHLHFN_00439	5.6e-11	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_00440	5.22e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
PFLHLHFN_00441	5.45e-72	-	-	-	-	-	-	-	-
PFLHLHFN_00443	5.2e-119	-	-	-	D	-	-	-	ftsk spoiiie
PFLHLHFN_00445	2.13e-53	-	-	-	-	-	-	-	-
PFLHLHFN_00446	4.61e-304	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
PFLHLHFN_00447	7.01e-207	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
PFLHLHFN_00448	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PFLHLHFN_00449	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
PFLHLHFN_00450	7.92e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PFLHLHFN_00451	1.08e-289	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PFLHLHFN_00452	2.73e-201	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
PFLHLHFN_00453	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFLHLHFN_00454	7.28e-97	-	-	-	K	-	-	-	acetyltransferase
PFLHLHFN_00455	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFLHLHFN_00456	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PFLHLHFN_00457	2.38e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PFLHLHFN_00458	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PFLHLHFN_00459	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PFLHLHFN_00460	2.53e-56	-	-	-	-	-	-	-	-
PFLHLHFN_00461	1.37e-219	-	-	-	GK	-	-	-	ROK family
PFLHLHFN_00462	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFLHLHFN_00463	0.0	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_00464	5.52e-113	-	-	-	-	-	-	-	-
PFLHLHFN_00465	5.17e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PFLHLHFN_00466	9.72e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PFLHLHFN_00467	1.42e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PFLHLHFN_00468	2.14e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PFLHLHFN_00469	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PFLHLHFN_00470	1.11e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PFLHLHFN_00471	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFLHLHFN_00472	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PFLHLHFN_00473	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PFLHLHFN_00474	4.29e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
PFLHLHFN_00475	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PFLHLHFN_00476	1.66e-143	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
PFLHLHFN_00478	1.43e-144	-	-	-	-	-	-	-	-
PFLHLHFN_00479	5.69e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFLHLHFN_00480	6.87e-93	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PFLHLHFN_00481	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PFLHLHFN_00482	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PFLHLHFN_00483	6.08e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PFLHLHFN_00484	1.11e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFLHLHFN_00485	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFLHLHFN_00486	4.39e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFLHLHFN_00487	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00488	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00489	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PFLHLHFN_00490	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PFLHLHFN_00492	9.39e-71	-	-	-	-	-	-	-	-
PFLHLHFN_00493	4.06e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PFLHLHFN_00494	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
PFLHLHFN_00495	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PFLHLHFN_00496	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PFLHLHFN_00497	9e-132	-	-	-	L	-	-	-	Integrase
PFLHLHFN_00498	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
PFLHLHFN_00499	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
PFLHLHFN_00500	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PFLHLHFN_00501	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_00502	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PFLHLHFN_00503	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PFLHLHFN_00504	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
PFLHLHFN_00505	4.1e-34	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PFLHLHFN_00506	7.44e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_00507	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PFLHLHFN_00508	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
PFLHLHFN_00509	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PFLHLHFN_00511	2.72e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
PFLHLHFN_00517	7.36e-155	-	-	-	-	-	-	-	-
PFLHLHFN_00518	6.81e-16	-	-	-	-	-	-	-	-
PFLHLHFN_00519	6.86e-33	-	-	-	-	-	-	-	-
PFLHLHFN_00520	1.32e-54	-	-	-	-	-	-	-	-
PFLHLHFN_00521	1.71e-16	-	-	-	S	-	-	-	Transposase
PFLHLHFN_00522	9.84e-18	-	-	-	-	-	-	-	-
PFLHLHFN_00524	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PFLHLHFN_00525	3.11e-200	-	-	-	S	-	-	-	domain, Protein
PFLHLHFN_00527	1.71e-30	-	-	-	S	-	-	-	Uncharacterized protein pXO2-11
PFLHLHFN_00528	4.84e-85	-	-	-	-	-	-	-	-
PFLHLHFN_00529	0.0	-	-	-	S	-	-	-	AAA-like domain
PFLHLHFN_00530	5.67e-134	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFLHLHFN_00531	4.87e-11	-	-	-	-	-	-	-	-
PFLHLHFN_00532	4.4e-49	-	-	-	-	-	-	-	-
PFLHLHFN_00533	6.39e-30	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
PFLHLHFN_00534	5.36e-57	-	-	-	-	-	-	-	-
PFLHLHFN_00535	2.15e-181	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
PFLHLHFN_00536	1.65e-40	-	-	-	-	-	-	-	-
PFLHLHFN_00537	1.57e-44	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
PFLHLHFN_00538	1.18e-278	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
PFLHLHFN_00539	0.0	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
PFLHLHFN_00540	1.91e-11	-	-	-	-	-	-	-	-
PFLHLHFN_00542	5.39e-37	-	-	-	-	-	-	-	-
PFLHLHFN_00545	4.79e-70	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFLHLHFN_00548	7.33e-289	-	-	-	-	-	-	-	-
PFLHLHFN_00550	1.96e-54	-	-	-	M	-	-	-	Glycosyl transferase family 2
PFLHLHFN_00551	8.94e-59	sunT	-	-	V	ko:K02021,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	Peptidase C39 family
PFLHLHFN_00553	1.58e-05	bdbA	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
PFLHLHFN_00554	5.36e-28	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	COG0526, thiol-disulfide isomerase and thioredoxins
PFLHLHFN_00557	1.38e-128	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
PFLHLHFN_00561	4.89e-28	-	-	-	-	-	-	-	-
PFLHLHFN_00565	4.27e-258	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	impB/mucB/samB family
PFLHLHFN_00567	7.04e-42	-	-	-	-	-	-	-	-
PFLHLHFN_00568	8.98e-156	-	-	-	D	-	-	-	AAA domain
PFLHLHFN_00569	0.0	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
PFLHLHFN_00570	5.94e-24	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00571	2.18e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PFLHLHFN_00572	1.11e-80	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00573	2.52e-111	traB	-	-	S	-	-	-	TraB family
PFLHLHFN_00578	6.16e-14	-	-	-	-	-	-	-	-
PFLHLHFN_00579	2.93e-195	-	-	-	-	-	-	-	-
PFLHLHFN_00580	3.23e-59	-	-	-	-	-	-	-	-
PFLHLHFN_00581	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PFLHLHFN_00582	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PFLHLHFN_00583	5.83e-24	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PFLHLHFN_00584	5.08e-229	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PFLHLHFN_00585	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PFLHLHFN_00586	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_00587	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PFLHLHFN_00588	8.97e-47	-	-	-	-	-	-	-	-
PFLHLHFN_00589	9.17e-54	-	-	-	-	-	-	-	-
PFLHLHFN_00591	8.34e-76	-	-	-	S	-	-	-	PrgU-like protein
PFLHLHFN_00592	4.27e-30	-	-	-	D	ko:K20382	ko02024,map02024	ko00000,ko00001	Glucan-binding protein C
PFLHLHFN_00593	3.48e-105	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PFLHLHFN_00594	2.96e-176	-	-	-	V	-	-	-	N-6 DNA Methylase
PFLHLHFN_00595	1.48e-136	-	-	-	L	-	-	-	PFAM Integrase catalytic
PFLHLHFN_00596	1.44e-57	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFLHLHFN_00597	4.23e-46	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_00599	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PFLHLHFN_00600	3.54e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PFLHLHFN_00602	5.22e-125	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
PFLHLHFN_00603	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
PFLHLHFN_00604	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PFLHLHFN_00606	1.45e-133	-	-	-	-	-	-	-	-
PFLHLHFN_00607	2.6e-37	-	-	-	-	-	-	-	-
PFLHLHFN_00608	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PFLHLHFN_00609	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PFLHLHFN_00610	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PFLHLHFN_00611	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PFLHLHFN_00612	2.63e-205	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PFLHLHFN_00613	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
PFLHLHFN_00614	2.44e-143	-	-	-	S	-	-	-	CYTH
PFLHLHFN_00615	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PFLHLHFN_00616	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PFLHLHFN_00617	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PFLHLHFN_00618	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PFLHLHFN_00619	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
PFLHLHFN_00620	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PFLHLHFN_00621	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PFLHLHFN_00622	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PFLHLHFN_00623	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PFLHLHFN_00624	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PFLHLHFN_00625	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PFLHLHFN_00626	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PFLHLHFN_00627	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
PFLHLHFN_00628	3.27e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PFLHLHFN_00629	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PFLHLHFN_00630	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFLHLHFN_00631	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PFLHLHFN_00632	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PFLHLHFN_00633	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PFLHLHFN_00634	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PFLHLHFN_00635	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PFLHLHFN_00636	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PFLHLHFN_00637	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PFLHLHFN_00638	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFLHLHFN_00639	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PFLHLHFN_00640	8.33e-27	-	-	-	-	-	-	-	-
PFLHLHFN_00641	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PFLHLHFN_00642	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PFLHLHFN_00643	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PFLHLHFN_00644	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PFLHLHFN_00645	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PFLHLHFN_00646	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PFLHLHFN_00647	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PFLHLHFN_00648	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PFLHLHFN_00649	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PFLHLHFN_00650	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PFLHLHFN_00651	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PFLHLHFN_00652	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PFLHLHFN_00653	0.0	-	-	-	S	-	-	-	SH3-like domain
PFLHLHFN_00654	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00655	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PFLHLHFN_00656	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PFLHLHFN_00657	5.46e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PFLHLHFN_00658	2.74e-06	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_00659	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PFLHLHFN_00660	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PFLHLHFN_00661	4.65e-219	-	-	-	L	-	-	-	Bifunctional protein
PFLHLHFN_00662	6.1e-186	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00663	9.92e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00664	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PFLHLHFN_00665	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PFLHLHFN_00666	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PFLHLHFN_00667	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PFLHLHFN_00668	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PFLHLHFN_00669	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PFLHLHFN_00670	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PFLHLHFN_00671	6.02e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PFLHLHFN_00672	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PFLHLHFN_00673	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PFLHLHFN_00674	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PFLHLHFN_00675	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PFLHLHFN_00676	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
PFLHLHFN_00677	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PFLHLHFN_00678	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PFLHLHFN_00679	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PFLHLHFN_00680	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFLHLHFN_00681	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PFLHLHFN_00682	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PFLHLHFN_00683	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PFLHLHFN_00684	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PFLHLHFN_00685	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PFLHLHFN_00686	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PFLHLHFN_00687	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PFLHLHFN_00688	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PFLHLHFN_00689	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PFLHLHFN_00690	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PFLHLHFN_00691	1.74e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PFLHLHFN_00692	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PFLHLHFN_00693	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFLHLHFN_00694	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFLHLHFN_00695	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PFLHLHFN_00696	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
PFLHLHFN_00697	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PFLHLHFN_00698	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PFLHLHFN_00699	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PFLHLHFN_00700	4.96e-270	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_00701	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PFLHLHFN_00702	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PFLHLHFN_00703	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PFLHLHFN_00704	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PFLHLHFN_00705	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PFLHLHFN_00706	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PFLHLHFN_00707	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PFLHLHFN_00708	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PFLHLHFN_00709	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00713	5.73e-153	-	-	-	-	-	-	-	-
PFLHLHFN_00714	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
PFLHLHFN_00715	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PFLHLHFN_00716	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PFLHLHFN_00717	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PFLHLHFN_00718	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PFLHLHFN_00719	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PFLHLHFN_00720	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PFLHLHFN_00721	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PFLHLHFN_00722	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PFLHLHFN_00723	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PFLHLHFN_00724	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PFLHLHFN_00725	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PFLHLHFN_00726	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
PFLHLHFN_00727	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PFLHLHFN_00728	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PFLHLHFN_00729	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PFLHLHFN_00730	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PFLHLHFN_00731	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PFLHLHFN_00732	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PFLHLHFN_00733	1.65e-180	-	-	-	-	-	-	-	-
PFLHLHFN_00734	2.54e-176	-	-	-	-	-	-	-	-
PFLHLHFN_00735	3.85e-193	-	-	-	-	-	-	-	-
PFLHLHFN_00736	3.49e-36	-	-	-	-	-	-	-	-
PFLHLHFN_00737	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PFLHLHFN_00738	4.01e-184	-	-	-	-	-	-	-	-
PFLHLHFN_00739	4.4e-215	-	-	-	-	-	-	-	-
PFLHLHFN_00740	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PFLHLHFN_00741	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PFLHLHFN_00742	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PFLHLHFN_00743	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PFLHLHFN_00744	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PFLHLHFN_00745	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
PFLHLHFN_00746	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PFLHLHFN_00747	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PFLHLHFN_00748	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PFLHLHFN_00749	1.66e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PFLHLHFN_00750	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PFLHLHFN_00751	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PFLHLHFN_00752	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PFLHLHFN_00753	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PFLHLHFN_00754	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PFLHLHFN_00755	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PFLHLHFN_00756	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PFLHLHFN_00757	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PFLHLHFN_00758	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PFLHLHFN_00759	9.67e-104	-	-	-	-	-	-	-	-
PFLHLHFN_00760	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
PFLHLHFN_00761	9.13e-157	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PFLHLHFN_00762	4.07e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PFLHLHFN_00763	3.81e-18	-	-	-	S	-	-	-	CsbD-like
PFLHLHFN_00764	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
PFLHLHFN_00765	1.29e-164	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_00766	6.91e-67	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PFLHLHFN_00767	0.0	-	-	-	L	-	-	-	Transposase DDE domain
PFLHLHFN_00768	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
PFLHLHFN_00769	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFLHLHFN_00770	1.93e-268	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFLHLHFN_00771	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
PFLHLHFN_00772	3.5e-114	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
PFLHLHFN_00773	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFLHLHFN_00774	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFLHLHFN_00775	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PFLHLHFN_00776	2.14e-154	-	-	-	C	-	-	-	nitroreductase
PFLHLHFN_00777	1.76e-52	-	-	-	-	-	-	-	-
PFLHLHFN_00778	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PFLHLHFN_00779	1.52e-103	-	-	-	-	-	-	-	-
PFLHLHFN_00780	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PFLHLHFN_00781	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PFLHLHFN_00782	7.44e-189	-	-	-	S	-	-	-	hydrolase
PFLHLHFN_00783	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
PFLHLHFN_00784	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PFLHLHFN_00785	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PFLHLHFN_00786	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
PFLHLHFN_00787	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PFLHLHFN_00788	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PFLHLHFN_00789	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PFLHLHFN_00790	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PFLHLHFN_00791	2.59e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PFLHLHFN_00792	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFLHLHFN_00793	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PFLHLHFN_00794	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PFLHLHFN_00795	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PFLHLHFN_00796	2.09e-110	-	-	-	-	-	-	-	-
PFLHLHFN_00797	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PFLHLHFN_00798	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00799	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00800	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_00801	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00802	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
PFLHLHFN_00803	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
PFLHLHFN_00804	8.41e-314	-	-	-	G	-	-	-	MFS/sugar transport protein
PFLHLHFN_00805	1.72e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PFLHLHFN_00806	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
PFLHLHFN_00807	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00808	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PFLHLHFN_00809	2.05e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFLHLHFN_00810	1.07e-165	-	-	-	F	-	-	-	glutamine amidotransferase
PFLHLHFN_00811	3.41e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PFLHLHFN_00812	3.97e-33	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PFLHLHFN_00813	1.11e-256	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PFLHLHFN_00814	1.53e-176	-	-	-	-	-	-	-	-
PFLHLHFN_00815	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
PFLHLHFN_00816	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PFLHLHFN_00817	2.33e-230	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PFLHLHFN_00818	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
PFLHLHFN_00819	5.93e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFLHLHFN_00820	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFLHLHFN_00821	1.45e-34	-	-	-	K	-	-	-	FCD
PFLHLHFN_00822	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
PFLHLHFN_00823	1.08e-229	-	-	-	L	-	-	-	DDE superfamily endonuclease
PFLHLHFN_00824	0.0	-	-	-	E	-	-	-	Amino acid permease
PFLHLHFN_00826	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PFLHLHFN_00827	1.96e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PFLHLHFN_00828	2.64e-46	-	-	-	-	-	-	-	-
PFLHLHFN_00829	1.67e-136	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
PFLHLHFN_00830	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PFLHLHFN_00831	6.91e-118	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PFLHLHFN_00832	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PFLHLHFN_00833	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PFLHLHFN_00834	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PFLHLHFN_00835	3.42e-194	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PFLHLHFN_00836	1.25e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PFLHLHFN_00837	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFLHLHFN_00838	2.85e-153	-	-	-	-	-	-	-	-
PFLHLHFN_00839	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
PFLHLHFN_00840	8.04e-190	-	-	-	S	-	-	-	hydrolase
PFLHLHFN_00841	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PFLHLHFN_00842	1.6e-220	ybbR	-	-	S	-	-	-	YbbR-like protein
PFLHLHFN_00843	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFLHLHFN_00844	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFLHLHFN_00845	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00846	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00847	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PFLHLHFN_00848	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PFLHLHFN_00849	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PFLHLHFN_00850	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PFLHLHFN_00851	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PFLHLHFN_00852	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PFLHLHFN_00853	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PFLHLHFN_00854	3.07e-124	-	-	-	-	-	-	-	-
PFLHLHFN_00855	1.18e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PFLHLHFN_00856	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFLHLHFN_00857	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PFLHLHFN_00858	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PFLHLHFN_00859	9.26e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PFLHLHFN_00861	0.0	-	-	-	-	-	-	-	-
PFLHLHFN_00862	0.0	ycaM	-	-	E	-	-	-	amino acid
PFLHLHFN_00863	3.49e-50	-	-	-	-	-	-	-	-
PFLHLHFN_00864	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFLHLHFN_00865	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PFLHLHFN_00866	1.11e-177	-	-	-	-	-	-	-	-
PFLHLHFN_00867	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PFLHLHFN_00868	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00869	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PFLHLHFN_00870	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PFLHLHFN_00871	2.45e-164	-	-	-	-	-	-	-	-
PFLHLHFN_00872	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PFLHLHFN_00873	7.8e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PFLHLHFN_00874	2.7e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PFLHLHFN_00875	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PFLHLHFN_00876	8.82e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFLHLHFN_00877	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
PFLHLHFN_00879	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PFLHLHFN_00880	3.77e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_00881	1.24e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PFLHLHFN_00882	9.29e-111	usp5	-	-	T	-	-	-	universal stress protein
PFLHLHFN_00883	8.61e-202	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PFLHLHFN_00884	1.67e-175	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PFLHLHFN_00885	1.02e-154	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_00886	1.83e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_00887	6.82e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PFLHLHFN_00888	5.18e-109	-	-	-	-	-	-	-	-
PFLHLHFN_00889	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PFLHLHFN_00890	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PFLHLHFN_00891	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PFLHLHFN_00892	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PFLHLHFN_00893	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PFLHLHFN_00894	1.69e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PFLHLHFN_00895	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PFLHLHFN_00896	3.11e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_00897	1.11e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PFLHLHFN_00898	5.67e-278	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
PFLHLHFN_00899	5.59e-98	-	-	-	-	-	-	-	-
PFLHLHFN_00900	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFLHLHFN_00901	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PFLHLHFN_00902	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
PFLHLHFN_00903	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PFLHLHFN_00904	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFLHLHFN_00905	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PFLHLHFN_00906	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFLHLHFN_00907	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PFLHLHFN_00908	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PFLHLHFN_00909	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PFLHLHFN_00910	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PFLHLHFN_00911	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
PFLHLHFN_00912	2.04e-226	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_00913	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PFLHLHFN_00914	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PFLHLHFN_00915	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFLHLHFN_00916	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
PFLHLHFN_00918	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PFLHLHFN_00919	1.63e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PFLHLHFN_00920	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_00921	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PFLHLHFN_00922	1.2e-41	-	-	-	-	-	-	-	-
PFLHLHFN_00923	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PFLHLHFN_00924	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PFLHLHFN_00925	0.0	-	-	-	-	-	-	-	-
PFLHLHFN_00926	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
PFLHLHFN_00928	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PFLHLHFN_00929	0.0	yhaN	-	-	L	-	-	-	AAA domain
PFLHLHFN_00930	4.24e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PFLHLHFN_00931	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PFLHLHFN_00932	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PFLHLHFN_00933	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PFLHLHFN_00934	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
PFLHLHFN_00936	4.24e-46	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PFLHLHFN_00937	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PFLHLHFN_00938	5.95e-72	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PFLHLHFN_00939	8.41e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PFLHLHFN_00940	5.32e-285	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PFLHLHFN_00941	6.09e-121	-	-	-	-	-	-	-	-
PFLHLHFN_00943	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
PFLHLHFN_00944	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PFLHLHFN_00945	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFLHLHFN_00946	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
PFLHLHFN_00947	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFLHLHFN_00948	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PFLHLHFN_00949	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PFLHLHFN_00950	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PFLHLHFN_00951	0.0	-	-	-	S	-	-	-	membrane
PFLHLHFN_00952	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PFLHLHFN_00953	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PFLHLHFN_00954	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PFLHLHFN_00955	3.25e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
PFLHLHFN_00956	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PFLHLHFN_00957	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PFLHLHFN_00958	3.84e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PFLHLHFN_00959	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
PFLHLHFN_00960	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PFLHLHFN_00961	2.37e-219	-	-	-	-	-	-	-	-
PFLHLHFN_00962	2.09e-205	-	-	-	-	-	-	-	-
PFLHLHFN_00966	6.78e-47	-	-	-	-	-	-	-	-
PFLHLHFN_00967	1.94e-165	-	-	-	S	-	-	-	interspecies interaction between organisms
PFLHLHFN_00968	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
PFLHLHFN_00969	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
PFLHLHFN_00970	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_00971	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PFLHLHFN_00972	2.65e-154	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PFLHLHFN_00973	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
PFLHLHFN_00974	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PFLHLHFN_00975	1.48e-166	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PFLHLHFN_00976	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFLHLHFN_00977	1.4e-74	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
PFLHLHFN_00978	2.58e-17	axe1	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	acetyl xylan esterase
PFLHLHFN_00979	6.9e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PFLHLHFN_00980	2.58e-13	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFLHLHFN_00981	1.59e-108	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFLHLHFN_00982	4.56e-24	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
PFLHLHFN_00983	1.06e-210	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PFLHLHFN_00984	6.09e-233	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PFLHLHFN_00986	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PFLHLHFN_00987	1.71e-128	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PFLHLHFN_00988	2.02e-137	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PFLHLHFN_00989	3e-219	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PFLHLHFN_00990	1.12e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PFLHLHFN_00991	3.95e-242	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
PFLHLHFN_00992	2.71e-16	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PFLHLHFN_00993	9.42e-267	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PFLHLHFN_00994	3.45e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_00995	2.28e-291	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PFLHLHFN_00996	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PFLHLHFN_00997	6.55e-129	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PFLHLHFN_00998	9.19e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_00999	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PFLHLHFN_01000	3.21e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFLHLHFN_01001	1.2e-147	-	-	-	I	-	-	-	Acid phosphatase homologues
PFLHLHFN_01002	9.17e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PFLHLHFN_01003	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PFLHLHFN_01004	7.27e-106	-	-	-	C	-	-	-	Flavodoxin
PFLHLHFN_01005	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PFLHLHFN_01006	2.88e-310	ynbB	-	-	P	-	-	-	aluminum resistance
PFLHLHFN_01007	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PFLHLHFN_01008	0.0	-	-	-	E	-	-	-	Amino acid permease
PFLHLHFN_01009	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
PFLHLHFN_01010	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PFLHLHFN_01011	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PFLHLHFN_01012	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PFLHLHFN_01013	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFLHLHFN_01014	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFLHLHFN_01015	2.15e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PFLHLHFN_01017	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
PFLHLHFN_01020	7.88e-59	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
PFLHLHFN_01023	6.57e-45	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PFLHLHFN_01024	1.49e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01025	7.56e-230	-	-	-	L	-	-	-	N-6 DNA Methylase
PFLHLHFN_01027	3.62e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFLHLHFN_01033	3.37e-15	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_01034	6.95e-21	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PFLHLHFN_01036	8.5e-10	-	-	-	M	-	-	-	oxidoreductase activity
PFLHLHFN_01037	3.24e-13	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_01042	2.66e-165	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PFLHLHFN_01046	6.51e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
PFLHLHFN_01047	8.52e-25	lysM	-	-	M	-	-	-	LysM domain
PFLHLHFN_01054	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
PFLHLHFN_01057	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
PFLHLHFN_01058	7.27e-42	-	-	-	-	-	-	-	-
PFLHLHFN_01059	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PFLHLHFN_01060	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PFLHLHFN_01061	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PFLHLHFN_01062	7.2e-40	-	-	-	-	-	-	-	-
PFLHLHFN_01063	5.49e-46	-	-	-	-	-	-	-	-
PFLHLHFN_01064	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PFLHLHFN_01065	2.52e-76	-	-	-	-	-	-	-	-
PFLHLHFN_01066	0.0	-	-	-	S	-	-	-	ABC transporter
PFLHLHFN_01067	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
PFLHLHFN_01068	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PFLHLHFN_01069	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
PFLHLHFN_01070	1.16e-101	-	-	-	-	-	-	-	-
PFLHLHFN_01071	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFLHLHFN_01072	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PFLHLHFN_01073	5.48e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PFLHLHFN_01074	8.77e-144	-	-	-	-	-	-	-	-
PFLHLHFN_01075	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
PFLHLHFN_01076	3.72e-55	-	-	-	-	-	-	-	-
PFLHLHFN_01077	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
PFLHLHFN_01078	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PFLHLHFN_01079	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PFLHLHFN_01080	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PFLHLHFN_01081	3.01e-54	-	-	-	-	-	-	-	-
PFLHLHFN_01082	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PFLHLHFN_01083	7.5e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFLHLHFN_01087	1.47e-243	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PFLHLHFN_01088	3.05e-184	epsB	-	-	M	-	-	-	biosynthesis protein
PFLHLHFN_01089	6.84e-161	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PFLHLHFN_01090	6.64e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PFLHLHFN_01091	1.1e-153	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
PFLHLHFN_01092	1.68e-199	-	-	-	M	-	-	-	Glycosyltransferase
PFLHLHFN_01093	2.64e-103	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
PFLHLHFN_01094	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
PFLHLHFN_01095	1.55e-29	-	-	-	-	-	-	-	-
PFLHLHFN_01096	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PFLHLHFN_01097	1.68e-185	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PFLHLHFN_01098	5.58e-92	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PFLHLHFN_01099	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PFLHLHFN_01100	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PFLHLHFN_01101	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PFLHLHFN_01102	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PFLHLHFN_01103	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PFLHLHFN_01104	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PFLHLHFN_01105	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFLHLHFN_01106	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PFLHLHFN_01107	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PFLHLHFN_01108	1.74e-274	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PFLHLHFN_01109	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PFLHLHFN_01110	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PFLHLHFN_01111	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PFLHLHFN_01112	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PFLHLHFN_01113	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PFLHLHFN_01114	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PFLHLHFN_01115	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PFLHLHFN_01116	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PFLHLHFN_01117	2.79e-102	-	-	-	-	-	-	-	-
PFLHLHFN_01118	2.14e-231	-	-	-	M	-	-	-	CHAP domain
PFLHLHFN_01119	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PFLHLHFN_01120	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PFLHLHFN_01121	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PFLHLHFN_01122	3.12e-65	-	-	-	-	-	-	-	-
PFLHLHFN_01123	5.57e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PFLHLHFN_01124	4.52e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PFLHLHFN_01125	2.07e-178	-	-	-	P	-	-	-	Voltage gated chloride channel
PFLHLHFN_01126	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
PFLHLHFN_01127	1.05e-69	-	-	-	-	-	-	-	-
PFLHLHFN_01128	7.17e-56	-	-	-	-	-	-	-	-
PFLHLHFN_01129	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PFLHLHFN_01130	0.0	-	-	-	E	-	-	-	amino acid
PFLHLHFN_01131	3.87e-199	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PFLHLHFN_01132	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
PFLHLHFN_01133	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PFLHLHFN_01134	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PFLHLHFN_01135	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PFLHLHFN_01136	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PFLHLHFN_01137	2.3e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFLHLHFN_01138	3.54e-166	-	-	-	S	-	-	-	(CBS) domain
PFLHLHFN_01139	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PFLHLHFN_01140	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PFLHLHFN_01141	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PFLHLHFN_01142	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
PFLHLHFN_01143	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PFLHLHFN_01144	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
PFLHLHFN_01145	1.36e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PFLHLHFN_01146	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PFLHLHFN_01147	1.37e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PFLHLHFN_01148	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFLHLHFN_01149	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PFLHLHFN_01150	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
PFLHLHFN_01152	7.14e-139	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PFLHLHFN_01155	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFLHLHFN_01156	0.0	potE	-	-	E	-	-	-	Amino Acid
PFLHLHFN_01157	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
PFLHLHFN_01158	0.0	-	-	-	-	-	-	-	-
PFLHLHFN_01159	5.87e-110	-	-	-	-	-	-	-	-
PFLHLHFN_01160	1.92e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
PFLHLHFN_01161	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
PFLHLHFN_01162	1.36e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PFLHLHFN_01163	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
PFLHLHFN_01164	5.97e-177	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PFLHLHFN_01165	2.34e-40	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PFLHLHFN_01166	6.89e-93	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
PFLHLHFN_01167	2.14e-48	-	-	-	-	-	-	-	-
PFLHLHFN_01168	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PFLHLHFN_01169	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PFLHLHFN_01170	3.56e-281	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PFLHLHFN_01171	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PFLHLHFN_01172	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PFLHLHFN_01173	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PFLHLHFN_01174	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PFLHLHFN_01175	4.35e-185	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PFLHLHFN_01176	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PFLHLHFN_01177	2.44e-210	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
PFLHLHFN_01178	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
PFLHLHFN_01179	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
PFLHLHFN_01181	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PFLHLHFN_01182	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PFLHLHFN_01183	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PFLHLHFN_01184	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
PFLHLHFN_01185	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
PFLHLHFN_01186	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PFLHLHFN_01187	7.99e-309	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PFLHLHFN_01188	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PFLHLHFN_01189	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PFLHLHFN_01190	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PFLHLHFN_01191	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
PFLHLHFN_01192	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PFLHLHFN_01193	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFLHLHFN_01194	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
PFLHLHFN_01195	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PFLHLHFN_01196	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PFLHLHFN_01197	3.36e-42	-	-	-	-	-	-	-	-
PFLHLHFN_01198	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
PFLHLHFN_01199	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01200	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PFLHLHFN_01201	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PFLHLHFN_01202	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
PFLHLHFN_01203	7.8e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PFLHLHFN_01204	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PFLHLHFN_01205	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PFLHLHFN_01206	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
PFLHLHFN_01207	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PFLHLHFN_01208	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PFLHLHFN_01209	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PFLHLHFN_01210	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_01211	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01212	1.4e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
PFLHLHFN_01213	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
PFLHLHFN_01214	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PFLHLHFN_01215	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PFLHLHFN_01216	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
PFLHLHFN_01217	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PFLHLHFN_01218	9.69e-25	-	-	-	-	-	-	-	-
PFLHLHFN_01219	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PFLHLHFN_01220	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PFLHLHFN_01221	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
PFLHLHFN_01222	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PFLHLHFN_01223	1.16e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PFLHLHFN_01224	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PFLHLHFN_01225	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01226	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PFLHLHFN_01227	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PFLHLHFN_01228	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
PFLHLHFN_01229	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
PFLHLHFN_01230	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
PFLHLHFN_01231	6.14e-107	-	-	-	-	-	-	-	-
PFLHLHFN_01232	1.67e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PFLHLHFN_01233	8.44e-65	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PFLHLHFN_01234	9.89e-112	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFLHLHFN_01235	1.98e-47	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFLHLHFN_01236	4.22e-41	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFLHLHFN_01237	2.77e-177	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PFLHLHFN_01238	1.4e-137	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PFLHLHFN_01239	2.53e-268	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFLHLHFN_01240	3.17e-67	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PFLHLHFN_01241	7.28e-80	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
PFLHLHFN_01242	3.44e-300	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PFLHLHFN_01243	4.9e-180	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PFLHLHFN_01244	2.42e-163	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PFLHLHFN_01245	1.9e-158	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PFLHLHFN_01246	7.01e-103	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PFLHLHFN_01247	2.27e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFLHLHFN_01248	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
PFLHLHFN_01250	1.2e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PFLHLHFN_01251	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PFLHLHFN_01252	9.56e-274	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PFLHLHFN_01253	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PFLHLHFN_01254	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_01255	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PFLHLHFN_01256	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PFLHLHFN_01257	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
PFLHLHFN_01258	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
PFLHLHFN_01259	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
PFLHLHFN_01260	1.09e-74	-	-	-	-	-	-	-	-
PFLHLHFN_01261	6.77e-111	-	-	-	-	-	-	-	-
PFLHLHFN_01262	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
PFLHLHFN_01263	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
PFLHLHFN_01264	9.07e-143	-	-	-	-	-	-	-	-
PFLHLHFN_01265	1.32e-137	-	-	-	-	-	-	-	-
PFLHLHFN_01266	1.07e-177	yicL	-	-	EG	-	-	-	EamA-like transporter family
PFLHLHFN_01267	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
PFLHLHFN_01268	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
PFLHLHFN_01269	5.51e-47	-	-	-	-	-	-	-	-
PFLHLHFN_01270	1.03e-07	-	-	-	-	-	-	-	-
PFLHLHFN_01271	1.02e-200	-	-	-	-	-	-	-	-
PFLHLHFN_01274	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
PFLHLHFN_01275	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PFLHLHFN_01276	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
PFLHLHFN_01277	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_01278	3.65e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFLHLHFN_01279	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_01280	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
PFLHLHFN_01281	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PFLHLHFN_01282	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PFLHLHFN_01283	1e-131	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PFLHLHFN_01284	1.22e-192	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
PFLHLHFN_01286	3.74e-180	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PFLHLHFN_01287	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
PFLHLHFN_01288	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PFLHLHFN_01289	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
PFLHLHFN_01290	5.49e-97	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PFLHLHFN_01291	7.93e-63	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PFLHLHFN_01292	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PFLHLHFN_01293	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PFLHLHFN_01294	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PFLHLHFN_01295	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01296	8.58e-60	-	-	-	-	-	-	-	-
PFLHLHFN_01297	3.56e-85	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_01298	1.08e-79	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PFLHLHFN_01299	7.61e-59	-	-	-	-	-	-	-	-
PFLHLHFN_01300	1.53e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01301	2.81e-102	-	-	-	E	-	-	-	Zn peptidase
PFLHLHFN_01302	1.06e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PFLHLHFN_01303	2.55e-26	-	-	-	-	-	-	-	-
PFLHLHFN_01304	1.95e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PFLHLHFN_01305	2.54e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
PFLHLHFN_01306	3e-118	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_01307	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_01308	5.76e-66	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PFLHLHFN_01310	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01311	0.000868	-	-	-	-	-	-	-	-
PFLHLHFN_01312	2.04e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PFLHLHFN_01313	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PFLHLHFN_01314	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PFLHLHFN_01315	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PFLHLHFN_01316	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PFLHLHFN_01317	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PFLHLHFN_01318	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PFLHLHFN_01319	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PFLHLHFN_01320	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PFLHLHFN_01321	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PFLHLHFN_01322	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PFLHLHFN_01323	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01324	3.41e-88	-	-	-	-	-	-	-	-
PFLHLHFN_01325	2.52e-32	-	-	-	-	-	-	-	-
PFLHLHFN_01326	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
PFLHLHFN_01327	2.13e-63	-	-	-	-	-	-	-	-
PFLHLHFN_01328	7.66e-32	-	-	-	-	-	-	-	-
PFLHLHFN_01329	7.87e-30	-	-	-	-	-	-	-	-
PFLHLHFN_01333	5.02e-180	blpT	-	-	-	-	-	-	-
PFLHLHFN_01334	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PFLHLHFN_01335	1.85e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PFLHLHFN_01336	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PFLHLHFN_01337	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PFLHLHFN_01338	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PFLHLHFN_01339	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PFLHLHFN_01340	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PFLHLHFN_01341	5.75e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PFLHLHFN_01342	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PFLHLHFN_01343	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_01344	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_01345	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01349	2.92e-204	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PFLHLHFN_01350	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PFLHLHFN_01351	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PFLHLHFN_01352	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFLHLHFN_01353	9.32e-109	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFLHLHFN_01354	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
PFLHLHFN_01355	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PFLHLHFN_01356	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PFLHLHFN_01357	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PFLHLHFN_01358	3.11e-256	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PFLHLHFN_01359	4.84e-42	-	-	-	-	-	-	-	-
PFLHLHFN_01360	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PFLHLHFN_01361	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PFLHLHFN_01362	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PFLHLHFN_01363	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFLHLHFN_01364	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PFLHLHFN_01365	7.72e-156	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PFLHLHFN_01366	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PFLHLHFN_01368	6.04e-49	-	-	-	-	-	-	-	-
PFLHLHFN_01369	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
PFLHLHFN_01370	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PFLHLHFN_01371	4.17e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PFLHLHFN_01372	8.21e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PFLHLHFN_01373	1.08e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFLHLHFN_01374	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PFLHLHFN_01375	2.57e-223	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PFLHLHFN_01376	5.31e-206	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PFLHLHFN_01377	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PFLHLHFN_01378	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_01379	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PFLHLHFN_01380	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PFLHLHFN_01381	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PFLHLHFN_01382	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PFLHLHFN_01383	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PFLHLHFN_01384	5.38e-39	-	-	-	-	-	-	-	-
PFLHLHFN_01385	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PFLHLHFN_01386	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PFLHLHFN_01387	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PFLHLHFN_01388	5.58e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFLHLHFN_01389	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PFLHLHFN_01390	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PFLHLHFN_01391	1.92e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PFLHLHFN_01392	1.05e-240	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PFLHLHFN_01393	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PFLHLHFN_01394	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PFLHLHFN_01395	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFLHLHFN_01396	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFLHLHFN_01397	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PFLHLHFN_01398	7.46e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFLHLHFN_01399	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PFLHLHFN_01400	2.15e-63	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_01401	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PFLHLHFN_01402	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PFLHLHFN_01403	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
PFLHLHFN_01404	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PFLHLHFN_01405	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFLHLHFN_01406	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PFLHLHFN_01407	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFLHLHFN_01408	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PFLHLHFN_01409	1.08e-95	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFLHLHFN_01410	1.87e-85	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PFLHLHFN_01411	4.46e-89	-	-	-	P	-	-	-	NhaP-type Na H and K H
PFLHLHFN_01412	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PFLHLHFN_01413	8.83e-187	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PFLHLHFN_01414	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PFLHLHFN_01415	1.72e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PFLHLHFN_01416	4.7e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFLHLHFN_01417	2.75e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
PFLHLHFN_01418	1.11e-41	yagE	-	-	E	-	-	-	Amino acid permease
PFLHLHFN_01419	2.25e-125	yagE	-	-	E	-	-	-	Amino acid permease
PFLHLHFN_01420	5.92e-191	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
PFLHLHFN_01421	4.87e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
PFLHLHFN_01422	6.97e-53	-	-	-	F	-	-	-	NUDIX domain
PFLHLHFN_01423	2.14e-104	-	-	-	S	-	-	-	AAA domain
PFLHLHFN_01424	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
PFLHLHFN_01425	2.06e-88	-	-	-	-	-	-	-	-
PFLHLHFN_01426	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PFLHLHFN_01427	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PFLHLHFN_01428	2.91e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PFLHLHFN_01429	2.28e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PFLHLHFN_01430	1.1e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PFLHLHFN_01431	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PFLHLHFN_01432	1.61e-70	-	-	-	-	-	-	-	-
PFLHLHFN_01433	3.15e-132	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
PFLHLHFN_01434	5.56e-07	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PFLHLHFN_01435	8.99e-100	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
PFLHLHFN_01436	5.77e-127	-	-	-	S	-	-	-	AAA domain
PFLHLHFN_01437	3.02e-232	-	-	-	-	-	-	-	-
PFLHLHFN_01438	8.53e-45	-	-	-	-	-	-	-	-
PFLHLHFN_01439	6.75e-101	-	-	-	S	-	-	-	HIRAN
PFLHLHFN_01440	1.3e-62	-	-	-	L	-	-	-	DNA helicase
PFLHLHFN_01441	1.04e-144	-	-	-	S	ko:K07459	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PFLHLHFN_01442	8.29e-84	-	-	-	S	-	-	-	TcpE family
PFLHLHFN_01443	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PFLHLHFN_01444	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PFLHLHFN_01445	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PFLHLHFN_01446	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PFLHLHFN_01447	3.3e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PFLHLHFN_01448	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PFLHLHFN_01449	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PFLHLHFN_01450	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PFLHLHFN_01451	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PFLHLHFN_01452	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PFLHLHFN_01453	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PFLHLHFN_01454	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PFLHLHFN_01455	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PFLHLHFN_01456	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PFLHLHFN_01457	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFLHLHFN_01458	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PFLHLHFN_01459	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PFLHLHFN_01460	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PFLHLHFN_01461	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PFLHLHFN_01462	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PFLHLHFN_01463	2.86e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PFLHLHFN_01464	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PFLHLHFN_01465	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PFLHLHFN_01466	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PFLHLHFN_01467	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PFLHLHFN_01468	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PFLHLHFN_01469	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PFLHLHFN_01470	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFLHLHFN_01471	1.29e-79	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PFLHLHFN_01472	1.02e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFLHLHFN_01473	5.5e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFLHLHFN_01474	6.51e-177	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFLHLHFN_01475	5.08e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PFLHLHFN_01476	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PFLHLHFN_01477	1.61e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PFLHLHFN_01478	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
PFLHLHFN_01479	1.2e-220	-	-	-	-	-	-	-	-
PFLHLHFN_01480	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_01482	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PFLHLHFN_01483	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PFLHLHFN_01484	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PFLHLHFN_01485	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PFLHLHFN_01486	1.23e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PFLHLHFN_01487	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
PFLHLHFN_01488	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_01489	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PFLHLHFN_01490	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PFLHLHFN_01491	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFLHLHFN_01492	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PFLHLHFN_01493	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
PFLHLHFN_01494	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PFLHLHFN_01495	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PFLHLHFN_01496	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PFLHLHFN_01497	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PFLHLHFN_01498	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PFLHLHFN_01499	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PFLHLHFN_01500	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PFLHLHFN_01501	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFLHLHFN_01502	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PFLHLHFN_01503	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PFLHLHFN_01504	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PFLHLHFN_01505	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PFLHLHFN_01506	1.13e-41	-	-	-	M	-	-	-	Lysin motif
PFLHLHFN_01507	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PFLHLHFN_01508	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PFLHLHFN_01509	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PFLHLHFN_01510	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFLHLHFN_01511	3.52e-293	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PFLHLHFN_01512	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFLHLHFN_01513	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_01514	9.44e-117	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_01515	2.56e-291	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PFLHLHFN_01516	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PFLHLHFN_01517	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PFLHLHFN_01518	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
PFLHLHFN_01519	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
PFLHLHFN_01520	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PFLHLHFN_01521	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PFLHLHFN_01522	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PFLHLHFN_01523	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PFLHLHFN_01524	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PFLHLHFN_01525	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PFLHLHFN_01526	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PFLHLHFN_01527	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFLHLHFN_01528	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFLHLHFN_01529	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_01530	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PFLHLHFN_01532	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFLHLHFN_01533	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PFLHLHFN_01534	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PFLHLHFN_01535	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PFLHLHFN_01536	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PFLHLHFN_01537	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PFLHLHFN_01538	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PFLHLHFN_01539	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PFLHLHFN_01540	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PFLHLHFN_01541	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PFLHLHFN_01542	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PFLHLHFN_01543	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PFLHLHFN_01544	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PFLHLHFN_01545	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PFLHLHFN_01546	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFLHLHFN_01547	5.43e-191	-	-	-	-	-	-	-	-
PFLHLHFN_01548	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PFLHLHFN_01549	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
PFLHLHFN_01550	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PFLHLHFN_01551	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PFLHLHFN_01552	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
PFLHLHFN_01553	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFLHLHFN_01554	1.72e-149	-	-	-	-	-	-	-	-
PFLHLHFN_01555	1.98e-168	-	-	-	-	-	-	-	-
PFLHLHFN_01556	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PFLHLHFN_01557	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PFLHLHFN_01558	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PFLHLHFN_01559	1.14e-235	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PFLHLHFN_01560	1.47e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFLHLHFN_01562	1.3e-162	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_01565	3.56e-47	-	-	-	-	-	-	-	-
PFLHLHFN_01566	4.13e-83	-	-	-	-	-	-	-	-
PFLHLHFN_01569	1.51e-159	-	-	-	-	-	-	-	-
PFLHLHFN_01570	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
PFLHLHFN_01571	1.24e-08	-	-	-	-	-	-	-	-
PFLHLHFN_01572	1.73e-48	-	-	-	-	-	-	-	-
PFLHLHFN_01573	0.0	snf	-	-	KL	-	-	-	domain protein
PFLHLHFN_01574	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PFLHLHFN_01575	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFLHLHFN_01576	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFLHLHFN_01577	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
PFLHLHFN_01578	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PFLHLHFN_01579	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PFLHLHFN_01580	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_01581	6.73e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_01582	1.71e-156	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PFLHLHFN_01583	7.98e-35	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_01584	4.68e-25	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PFLHLHFN_01585	8.24e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PFLHLHFN_01586	7.62e-32	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_01588	1.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_01589	5.85e-67	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_01591	2.19e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
PFLHLHFN_01592	2.78e-45	-	-	-	-	-	-	-	-
PFLHLHFN_01595	4.97e-29	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PFLHLHFN_01597	2.62e-155	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PFLHLHFN_01599	1.47e-18	-	-	-	-	-	-	-	-
PFLHLHFN_01600	1.19e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
PFLHLHFN_01601	1.13e-24	-	-	-	EL	-	-	-	Toprim-like
PFLHLHFN_01602	3.22e-121	ydiM	-	-	G	-	-	-	Major facilitator superfamily
PFLHLHFN_01603	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PFLHLHFN_01604	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFLHLHFN_01605	1.72e-92	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFLHLHFN_01606	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PFLHLHFN_01607	5.5e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PFLHLHFN_01608	1.8e-34	-	-	-	-	-	-	-	-
PFLHLHFN_01609	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
PFLHLHFN_01610	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PFLHLHFN_01611	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PFLHLHFN_01612	2.77e-292	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PFLHLHFN_01613	5.84e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
PFLHLHFN_01614	1.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
PFLHLHFN_01615	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
PFLHLHFN_01616	1.89e-23	-	-	-	-	-	-	-	-
PFLHLHFN_01617	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
PFLHLHFN_01618	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PFLHLHFN_01619	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
PFLHLHFN_01620	4.48e-34	-	-	-	-	-	-	-	-
PFLHLHFN_01621	1.07e-35	-	-	-	-	-	-	-	-
PFLHLHFN_01622	1.95e-45	-	-	-	-	-	-	-	-
PFLHLHFN_01623	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
PFLHLHFN_01624	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PFLHLHFN_01625	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PFLHLHFN_01626	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PFLHLHFN_01627	8.32e-157	vanR	-	-	K	-	-	-	response regulator
PFLHLHFN_01629	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PFLHLHFN_01630	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01631	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01633	3.11e-13	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PFLHLHFN_01634	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
PFLHLHFN_01635	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
PFLHLHFN_01636	3.92e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PFLHLHFN_01637	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
PFLHLHFN_01638	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
PFLHLHFN_01639	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PFLHLHFN_01640	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
PFLHLHFN_01642	1.09e-46	-	-	-	-	-	-	-	-
PFLHLHFN_01644	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PFLHLHFN_01645	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PFLHLHFN_01646	0.0	yycH	-	-	S	-	-	-	YycH protein
PFLHLHFN_01647	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
PFLHLHFN_01648	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PFLHLHFN_01649	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PFLHLHFN_01650	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PFLHLHFN_01651	1.12e-178	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
PFLHLHFN_01652	3.93e-46	-	-	-	-	-	-	-	-
PFLHLHFN_01653	2.58e-31	-	-	-	-	-	-	-	-
PFLHLHFN_01658	3.38e-119	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
PFLHLHFN_01661	4.79e-190	-	-	-	S	-	-	-	Glucosyl transferase GtrII
PFLHLHFN_01663	2.06e-86	-	-	-	-	-	-	-	-
PFLHLHFN_01667	7.27e-63	-	-	-	-	-	-	-	-
PFLHLHFN_01668	6.3e-109	-	-	-	S	-	-	-	PcfJ-like protein
PFLHLHFN_01669	5.49e-117	-	-	-	S	-	-	-	PcfK-like protein
PFLHLHFN_01672	1e-156	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PFLHLHFN_01673	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PFLHLHFN_01674	3.68e-276	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PFLHLHFN_01675	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
PFLHLHFN_01676	0.0	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_01678	2.52e-303	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PFLHLHFN_01679	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PFLHLHFN_01680	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PFLHLHFN_01681	0.0	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PFLHLHFN_01682	5.28e-215	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PFLHLHFN_01683	3.53e-63	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
PFLHLHFN_01684	1.55e-82	-	-	-	M	-	-	-	SIS domain
PFLHLHFN_01685	8.46e-98	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
PFLHLHFN_01686	1.38e-46	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PFLHLHFN_01687	3.94e-254	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PFLHLHFN_01688	3.05e-53	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_01689	2.39e-85	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PFLHLHFN_01690	1.94e-188	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PFLHLHFN_01691	3.38e-91	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PFLHLHFN_01693	2.94e-94	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
PFLHLHFN_01694	5.18e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PFLHLHFN_01695	2.56e-66	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
PFLHLHFN_01696	2.38e-130	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PFLHLHFN_01697	2.82e-97	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
PFLHLHFN_01699	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PFLHLHFN_01700	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFLHLHFN_01701	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFLHLHFN_01702	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PFLHLHFN_01703	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PFLHLHFN_01704	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PFLHLHFN_01705	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PFLHLHFN_01706	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PFLHLHFN_01707	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PFLHLHFN_01708	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PFLHLHFN_01709	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFLHLHFN_01710	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFLHLHFN_01711	1.75e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PFLHLHFN_01712	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
PFLHLHFN_01740	1.1e-128	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_01741	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PFLHLHFN_01742	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PFLHLHFN_01743	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PFLHLHFN_01744	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PFLHLHFN_01745	1.25e-192	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PFLHLHFN_01746	2.47e-254	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PFLHLHFN_01747	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PFLHLHFN_01748	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PFLHLHFN_01749	1.02e-156	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PFLHLHFN_01750	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PFLHLHFN_01751	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PFLHLHFN_01752	4.63e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PFLHLHFN_01753	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PFLHLHFN_01754	3.52e-163	csrR	-	-	K	-	-	-	response regulator
PFLHLHFN_01755	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PFLHLHFN_01756	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
PFLHLHFN_01757	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PFLHLHFN_01758	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PFLHLHFN_01759	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PFLHLHFN_01760	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PFLHLHFN_01761	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PFLHLHFN_01762	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PFLHLHFN_01763	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PFLHLHFN_01764	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PFLHLHFN_01765	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PFLHLHFN_01766	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PFLHLHFN_01767	3.74e-62	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PFLHLHFN_01768	3.83e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PFLHLHFN_01769	7.58e-134	-	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	Excalibur calcium-binding domain
PFLHLHFN_01770	3.65e-92	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
PFLHLHFN_01771	2.4e-54	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
PFLHLHFN_01772	7.3e-116	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
PFLHLHFN_01773	2.3e-57	-	-	-	-	-	-	-	-
PFLHLHFN_01774	1.55e-115	-	-	-	-	-	-	-	-
PFLHLHFN_01775	1.96e-141	-	-	-	K	-	-	-	Replication-relaxation
PFLHLHFN_01776	0.0	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
PFLHLHFN_01777	0.0	-	-	-	M	-	-	-	Membrane
PFLHLHFN_01779	0.0	-	-	-	U	-	-	-	AAA-like domain
PFLHLHFN_01780	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PFLHLHFN_01781	3.17e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PFLHLHFN_01783	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
PFLHLHFN_01785	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01786	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
PFLHLHFN_01788	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_01789	4.82e-144	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_01792	2.41e-39	-	-	-	-	-	-	-	-
PFLHLHFN_01793	6.97e-289	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PFLHLHFN_01794	7.15e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PFLHLHFN_01795	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PFLHLHFN_01797	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PFLHLHFN_01798	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PFLHLHFN_01799	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PFLHLHFN_01800	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PFLHLHFN_01801	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PFLHLHFN_01802	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_01803	9.96e-45	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_01804	2.13e-42	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PFLHLHFN_01805	7.02e-36	-	-	-	-	-	-	-	-
PFLHLHFN_01806	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
PFLHLHFN_01807	5.5e-155	-	-	-	-	-	-	-	-
PFLHLHFN_01808	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PFLHLHFN_01809	3.58e-251	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PFLHLHFN_01810	2.61e-23	-	-	-	-	-	-	-	-
PFLHLHFN_01811	3.15e-121	-	-	-	S	-	-	-	membrane
PFLHLHFN_01812	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
PFLHLHFN_01813	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PFLHLHFN_01814	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PFLHLHFN_01815	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PFLHLHFN_01816	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
PFLHLHFN_01817	7.62e-223	-	-	-	-	-	-	-	-
PFLHLHFN_01818	1.36e-211	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PFLHLHFN_01819	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PFLHLHFN_01820	4.26e-22	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
PFLHLHFN_01821	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFLHLHFN_01822	5.23e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PFLHLHFN_01823	1.48e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFLHLHFN_01824	1.07e-141	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
PFLHLHFN_01825	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
PFLHLHFN_01826	4.87e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PFLHLHFN_01827	1.17e-38	-	-	-	-	-	-	-	-
PFLHLHFN_01828	4.65e-184	-	-	-	D	-	-	-	AAA domain
PFLHLHFN_01829	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
PFLHLHFN_01830	1.14e-164	-	-	-	S	-	-	-	Fic/DOC family
PFLHLHFN_01833	4.19e-92	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PFLHLHFN_01834	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
PFLHLHFN_01835	8.85e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PFLHLHFN_01836	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PFLHLHFN_01837	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PFLHLHFN_01838	2.75e-130	-	-	-	I	-	-	-	PAP2 superfamily
PFLHLHFN_01839	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PFLHLHFN_01841	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PFLHLHFN_01842	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PFLHLHFN_01843	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
PFLHLHFN_01844	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
PFLHLHFN_01845	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PFLHLHFN_01847	7.74e-61	-	-	-	-	-	-	-	-
PFLHLHFN_01848	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PFLHLHFN_01849	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PFLHLHFN_01850	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFLHLHFN_01851	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PFLHLHFN_01852	1.74e-111	-	-	-	-	-	-	-	-
PFLHLHFN_01853	7.76e-98	-	-	-	-	-	-	-	-
PFLHLHFN_01854	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PFLHLHFN_01855	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PFLHLHFN_01856	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PFLHLHFN_01857	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PFLHLHFN_01858	3.65e-84	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PFLHLHFN_01861	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PFLHLHFN_01864	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PFLHLHFN_01865	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_01867	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PFLHLHFN_01868	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PFLHLHFN_01869	1.32e-151	-	-	-	S	-	-	-	Putative esterase
PFLHLHFN_01870	1.81e-270	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PFLHLHFN_01871	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PFLHLHFN_01872	3.75e-168	-	-	-	K	-	-	-	rpiR family
PFLHLHFN_01873	1.29e-27	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PFLHLHFN_01874	2.46e-302	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_01875	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_01876	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PFLHLHFN_01877	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PFLHLHFN_01878	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PFLHLHFN_01879	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PFLHLHFN_01880	1.69e-06	-	-	-	-	-	-	-	-
PFLHLHFN_01881	2.1e-31	-	-	-	-	-	-	-	-
PFLHLHFN_01882	2.63e-50	-	-	-	-	-	-	-	-
PFLHLHFN_01883	1.25e-143	-	-	-	K	-	-	-	WHG domain
PFLHLHFN_01884	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PFLHLHFN_01885	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PFLHLHFN_01886	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PFLHLHFN_01887	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PFLHLHFN_01888	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
PFLHLHFN_01889	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PFLHLHFN_01890	1.18e-190	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PFLHLHFN_01891	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PFLHLHFN_01892	2.48e-196	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PFLHLHFN_01893	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PFLHLHFN_01894	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PFLHLHFN_01895	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PFLHLHFN_01896	3.31e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFLHLHFN_01897	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
PFLHLHFN_01898	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PFLHLHFN_01899	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PFLHLHFN_01900	2.4e-297	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
PFLHLHFN_01901	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PFLHLHFN_01902	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
PFLHLHFN_01903	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PFLHLHFN_01904	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
PFLHLHFN_01905	4.04e-29	-	-	-	-	-	-	-	-
PFLHLHFN_01906	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
PFLHLHFN_01907	1.13e-126	-	-	-	-	-	-	-	-
PFLHLHFN_01908	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PFLHLHFN_01909	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PFLHLHFN_01910	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_01911	2.27e-179	-	-	-	-	-	-	-	-
PFLHLHFN_01915	2.23e-48	-	-	-	-	-	-	-	-
PFLHLHFN_01916	2.52e-76	-	-	-	S	-	-	-	Cupredoxin-like domain
PFLHLHFN_01917	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
PFLHLHFN_01918	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PFLHLHFN_01919	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
PFLHLHFN_01920	7.41e-136	-	-	-	-	-	-	-	-
PFLHLHFN_01921	1.03e-65	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PFLHLHFN_01924	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
PFLHLHFN_01925	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PFLHLHFN_01926	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PFLHLHFN_01927	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PFLHLHFN_01928	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PFLHLHFN_01929	5.47e-151	-	-	-	-	-	-	-	-
PFLHLHFN_01930	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFLHLHFN_01932	1.22e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFLHLHFN_01933	2e-149	-	-	-	S	-	-	-	Peptidase family M23
PFLHLHFN_01934	3.51e-96	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
PFLHLHFN_01935	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PFLHLHFN_01936	1.2e-30	-	-	-	-	-	-	-	-
PFLHLHFN_01937	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PFLHLHFN_01938	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PFLHLHFN_01939	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PFLHLHFN_01940	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
PFLHLHFN_01941	7.91e-14	-	-	-	-	-	-	-	-
PFLHLHFN_01942	2.41e-66	-	-	-	-	-	-	-	-
PFLHLHFN_01943	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
PFLHLHFN_01944	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
PFLHLHFN_01946	5.26e-15	-	-	-	-	-	-	-	-
PFLHLHFN_01947	3.35e-55	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_01948	3.74e-182	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PFLHLHFN_01949	7.92e-221	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PFLHLHFN_01950	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PFLHLHFN_01951	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PFLHLHFN_01952	7.32e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFLHLHFN_01953	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PFLHLHFN_01954	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PFLHLHFN_01955	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PFLHLHFN_01956	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PFLHLHFN_01957	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PFLHLHFN_01958	1.13e-115	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
PFLHLHFN_01959	5.77e-39	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PFLHLHFN_01967	1.61e-155	-	-	-	S	-	-	-	Phage minor structural protein
PFLHLHFN_01969	7.57e-134	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PFLHLHFN_01977	6.39e-66	-	-	-	S	-	-	-	Phage capsid family
PFLHLHFN_01978	2.93e-108	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PFLHLHFN_01979	3.53e-168	-	-	-	S	-	-	-	Phage portal protein
PFLHLHFN_01981	0.0	-	-	-	S	-	-	-	Phage Terminase
PFLHLHFN_01984	1.21e-74	-	-	-	S	-	-	-	Phage terminase, small subunit
PFLHLHFN_01985	1.34e-62	-	-	-	L	-	-	-	HNH nucleases
PFLHLHFN_01990	3.85e-49	-	-	-	S	-	-	-	VRR_NUC
PFLHLHFN_02001	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
PFLHLHFN_02002	1.41e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
PFLHLHFN_02003	1.07e-182	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PFLHLHFN_02005	8.83e-88	-	-	-	S	-	-	-	AAA domain
PFLHLHFN_02011	5.99e-61	-	-	-	-	-	-	-	-
PFLHLHFN_02012	1.23e-101	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
PFLHLHFN_02013	2.69e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_02014	2.15e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_02017	8.76e-146	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_02018	2.29e-41	-	-	-	-	-	-	-	-
PFLHLHFN_02019	1.1e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PFLHLHFN_02020	7.49e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PFLHLHFN_02021	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PFLHLHFN_02022	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PFLHLHFN_02023	3.28e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PFLHLHFN_02024	7.82e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PFLHLHFN_02025	1.27e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PFLHLHFN_02026	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFLHLHFN_02027	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PFLHLHFN_02028	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PFLHLHFN_02029	2.19e-100	-	-	-	S	-	-	-	ASCH
PFLHLHFN_02030	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PFLHLHFN_02031	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PFLHLHFN_02032	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PFLHLHFN_02033	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFLHLHFN_02034	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFLHLHFN_02035	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PFLHLHFN_02036	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PFLHLHFN_02037	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PFLHLHFN_02038	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFLHLHFN_02039	1.75e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PFLHLHFN_02040	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PFLHLHFN_02041	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PFLHLHFN_02042	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFLHLHFN_02043	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PFLHLHFN_02045	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PFLHLHFN_02046	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PFLHLHFN_02047	8.21e-200	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PFLHLHFN_02048	4.73e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PFLHLHFN_02050	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
PFLHLHFN_02051	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PFLHLHFN_02052	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PFLHLHFN_02053	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PFLHLHFN_02054	1.13e-155	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PFLHLHFN_02057	8.77e-220	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PFLHLHFN_02058	2.16e-39	-	-	-	-	-	-	-	-
PFLHLHFN_02059	6.31e-27	-	-	-	-	-	-	-	-
PFLHLHFN_02062	1.75e-26	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
PFLHLHFN_02063	4.37e-38	-	-	-	-	-	-	-	-
PFLHLHFN_02071	3.57e-141	-	-	-	S	-	-	-	Baseplate J-like protein
PFLHLHFN_02072	1.55e-40	-	-	-	-	-	-	-	-
PFLHLHFN_02073	1.66e-48	-	-	-	-	-	-	-	-
PFLHLHFN_02074	2.15e-126	-	-	-	-	-	-	-	-
PFLHLHFN_02075	1.62e-59	-	-	-	-	-	-	-	-
PFLHLHFN_02076	4.24e-53	-	-	-	M	-	-	-	LysM domain
PFLHLHFN_02077	1.13e-236	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PFLHLHFN_02080	1.2e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
PFLHLHFN_02083	6.61e-24	-	-	-	-	-	-	-	-
PFLHLHFN_02084	2.36e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4054)
PFLHLHFN_02086	8.98e-25	-	-	-	-	-	-	-	-
PFLHLHFN_02087	5.02e-70	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
PFLHLHFN_02088	2.36e-27	-	-	-	S	-	-	-	Lysin motif
PFLHLHFN_02089	5.57e-69	-	-	-	S	-	-	-	Phage Mu protein F like protein
PFLHLHFN_02090	1.16e-110	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
PFLHLHFN_02091	4.27e-234	-	-	-	S	-	-	-	Terminase-like family
PFLHLHFN_02094	9.77e-27	-	-	-	S	-	-	-	N-methyltransferase activity
PFLHLHFN_02102	3.69e-15	-	-	-	S	-	-	-	VRR_NUC
PFLHLHFN_02104	7.58e-90	-	-	-	S	-	-	-	ORF6C domain
PFLHLHFN_02109	5.95e-24	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
PFLHLHFN_02111	2.8e-38	-	-	-	K	-	-	-	Helix-turn-helix domain
PFLHLHFN_02112	4.86e-54	-	-	-	S	-	-	-	ERF superfamily
PFLHLHFN_02113	4.51e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
PFLHLHFN_02121	6.19e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_02122	7.75e-24	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
PFLHLHFN_02124	3.93e-05	-	-	-	-	-	-	-	-
PFLHLHFN_02125	2.73e-112	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_02126	2.93e-16	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PFLHLHFN_02127	4.3e-66	-	-	-	-	-	-	-	-
PFLHLHFN_02128	8.51e-50	-	-	-	-	-	-	-	-
PFLHLHFN_02129	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
PFLHLHFN_02130	6.78e-24	-	-	-	S	-	-	-	Alpha beta hydrolase
PFLHLHFN_02131	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PFLHLHFN_02132	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PFLHLHFN_02133	8.74e-62	-	-	-	-	-	-	-	-
PFLHLHFN_02134	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PFLHLHFN_02135	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PFLHLHFN_02136	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PFLHLHFN_02137	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PFLHLHFN_02138	8.31e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PFLHLHFN_02139	3.68e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PFLHLHFN_02140	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PFLHLHFN_02141	8.81e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PFLHLHFN_02142	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PFLHLHFN_02143	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PFLHLHFN_02144	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
PFLHLHFN_02145	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
PFLHLHFN_02146	8.13e-169	-	-	-	G	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PFLHLHFN_02147	0.0	-	3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
PFLHLHFN_02148	4.34e-198	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, fructose-specific IIC component
PFLHLHFN_02149	5.84e-50	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 9.98
PFLHLHFN_02150	2.4e-54	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFLHLHFN_02152	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFLHLHFN_02153	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PFLHLHFN_02154	3.69e-30	-	-	-	-	-	-	-	-
PFLHLHFN_02155	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
PFLHLHFN_02156	1.68e-55	-	-	-	-	-	-	-	-
PFLHLHFN_02157	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
PFLHLHFN_02158	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PFLHLHFN_02159	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PFLHLHFN_02160	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PFLHLHFN_02161	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PFLHLHFN_02162	2.33e-120	-	-	-	S	-	-	-	VanZ like family
PFLHLHFN_02163	3.9e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PFLHLHFN_02164	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFLHLHFN_02166	1.08e-69	-	-	-	L	-	-	-	Transposase and inactivated derivatives
PFLHLHFN_02167	6.56e-86	sagB	-	-	C	-	-	-	Nitroreductase family
PFLHLHFN_02169	8.25e-65	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
PFLHLHFN_02170	9.75e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PFLHLHFN_02172	3.5e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PFLHLHFN_02173	4.04e-36	-	-	-	-	-	-	-	-
PFLHLHFN_02174	1.33e-72	-	-	-	-	-	-	-	-
PFLHLHFN_02175	1.74e-185	-	-	-	S	-	-	-	Replication initiation factor
PFLHLHFN_02176	1.36e-171	-	-	-	D	-	-	-	Ftsk spoiiie family protein
PFLHLHFN_02177	7.06e-110	-	-	-	-	-	-	-	-
PFLHLHFN_02178	7.2e-84	-	-	-	-	-	-	-	-
PFLHLHFN_02181	4.38e-150	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PFLHLHFN_02182	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PFLHLHFN_02183	4.8e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PFLHLHFN_02184	3.8e-80	-	-	-	-	-	-	-	-
PFLHLHFN_02185	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PFLHLHFN_02186	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PFLHLHFN_02187	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PFLHLHFN_02188	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PFLHLHFN_02189	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PFLHLHFN_02190	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PFLHLHFN_02191	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFLHLHFN_02192	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PFLHLHFN_02193	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PFLHLHFN_02194	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PFLHLHFN_02195	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_02196	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PFLHLHFN_02197	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PFLHLHFN_02198	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PFLHLHFN_02199	1.47e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PFLHLHFN_02200	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PFLHLHFN_02201	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PFLHLHFN_02202	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PFLHLHFN_02203	7.81e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PFLHLHFN_02204	4.65e-14	-	-	-	-	-	-	-	-
PFLHLHFN_02205	1.42e-57	-	-	-	-	-	-	-	-
PFLHLHFN_02206	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PFLHLHFN_02207	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PFLHLHFN_02208	1.34e-162	-	-	-	-	-	-	-	-
PFLHLHFN_02209	1.08e-307	-	-	-	S	-	-	-	response to antibiotic
PFLHLHFN_02210	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PFLHLHFN_02211	3.99e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PFLHLHFN_02212	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PFLHLHFN_02213	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PFLHLHFN_02214	4.25e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PFLHLHFN_02215	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PFLHLHFN_02216	9.89e-74	-	-	-	-	-	-	-	-
PFLHLHFN_02217	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PFLHLHFN_02218	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PFLHLHFN_02219	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PFLHLHFN_02220	2.71e-222	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PFLHLHFN_02221	6.46e-27	-	-	-	-	-	-	-	-
PFLHLHFN_02222	1.59e-268	-	-	-	-	-	-	-	-
PFLHLHFN_02223	6.57e-175	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_02224	1.14e-154	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_02225	1.06e-133	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PFLHLHFN_02226	2.35e-58	-	-	-	-	-	-	-	-
PFLHLHFN_02227	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PFLHLHFN_02228	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
PFLHLHFN_02229	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PFLHLHFN_02230	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PFLHLHFN_02231	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PFLHLHFN_02232	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PFLHLHFN_02233	2.37e-242	-	-	-	T	-	-	-	GHKL domain
PFLHLHFN_02234	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PFLHLHFN_02235	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PFLHLHFN_02236	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PFLHLHFN_02237	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
PFLHLHFN_02238	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
PFLHLHFN_02239	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
PFLHLHFN_02240	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PFLHLHFN_02241	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PFLHLHFN_02242	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PFLHLHFN_02243	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PFLHLHFN_02244	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PFLHLHFN_02245	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PFLHLHFN_02246	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
PFLHLHFN_02247	2.52e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PFLHLHFN_02248	1.15e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PFLHLHFN_02249	9.75e-20	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_02250	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PFLHLHFN_02251	3.31e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PFLHLHFN_02253	6.58e-175	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PFLHLHFN_02254	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PFLHLHFN_02255	7.82e-80	-	-	-	-	-	-	-	-
PFLHLHFN_02256	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PFLHLHFN_02257	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
PFLHLHFN_02258	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
PFLHLHFN_02259	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PFLHLHFN_02260	8.12e-60	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PFLHLHFN_02261	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PFLHLHFN_02262	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PFLHLHFN_02263	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PFLHLHFN_02264	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PFLHLHFN_02265	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PFLHLHFN_02266	5.32e-35	-	-	-	C	ko:K21832	-	ko00000	nitric oxide dioxygenase activity
PFLHLHFN_02267	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PFLHLHFN_02268	1.22e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PFLHLHFN_02269	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PFLHLHFN_02270	1.4e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PFLHLHFN_02271	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PFLHLHFN_02272	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PFLHLHFN_02273	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
PFLHLHFN_02274	1.07e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PFLHLHFN_02275	1.28e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PFLHLHFN_02276	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
PFLHLHFN_02277	3.77e-86	-	-	-	K	-	-	-	HxlR family
PFLHLHFN_02278	9.35e-63	-	-	-	-	-	-	-	-
PFLHLHFN_02279	2.1e-270	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
PFLHLHFN_02280	1.44e-80	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PFLHLHFN_02282	5.74e-69	-	-	-	-	-	-	-	-
PFLHLHFN_02283	7.51e-174	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PFLHLHFN_02284	1.14e-143	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
PFLHLHFN_02285	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
PFLHLHFN_02286	3.59e-69	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PFLHLHFN_02287	5.36e-100	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PFLHLHFN_02289	2.85e-54	-	-	-	-	-	-	-	-
PFLHLHFN_02290	8.49e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PFLHLHFN_02292	5.32e-190	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFLHLHFN_02293	6.87e-27	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFLHLHFN_02294	4.54e-135	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_02295	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PFLHLHFN_02296	1.21e-40	-	-	-	-	-	-	-	-
PFLHLHFN_02297	2.5e-136	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
PFLHLHFN_02298	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
PFLHLHFN_02299	4.12e-205	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
PFLHLHFN_02300	5.38e-184	-	-	-	K	-	-	-	LysR substrate binding domain
PFLHLHFN_02301	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PFLHLHFN_02302	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PFLHLHFN_02303	3.28e-101	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PFLHLHFN_02304	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
PFLHLHFN_02306	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PFLHLHFN_02308	4.87e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PFLHLHFN_02309	3.23e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFLHLHFN_02310	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PFLHLHFN_02311	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFLHLHFN_02312	2.08e-95	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PFLHLHFN_02313	2.42e-69	-	-	-	S	-	-	-	Abi-like protein
PFLHLHFN_02314	7.24e-284	-	-	-	S	-	-	-	SLAP domain
PFLHLHFN_02315	9.04e-162	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PFLHLHFN_02316	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PFLHLHFN_02317	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_02318	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PFLHLHFN_02319	1.38e-95	-	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_02320	2.58e-45	-	-	-	-	-	-	-	-
PFLHLHFN_02323	3.3e-42	-	-	-	-	-	-	-	-
PFLHLHFN_02324	3.98e-97	-	-	-	M	-	-	-	LysM domain
PFLHLHFN_02325	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PFLHLHFN_02326	0.0	-	-	-	L	-	-	-	Nuclease-related domain
PFLHLHFN_02327	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PFLHLHFN_02328	2.31e-148	-	-	-	S	-	-	-	repeat protein
PFLHLHFN_02329	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
PFLHLHFN_02330	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PFLHLHFN_02331	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PFLHLHFN_02332	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PFLHLHFN_02333	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PFLHLHFN_02334	1.22e-55	-	-	-	-	-	-	-	-
PFLHLHFN_02335	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PFLHLHFN_02336	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PFLHLHFN_02337	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PFLHLHFN_02338	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PFLHLHFN_02339	4.01e-192	ylmH	-	-	S	-	-	-	S4 domain protein
PFLHLHFN_02340	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PFLHLHFN_02341	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PFLHLHFN_02342	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PFLHLHFN_02343	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PFLHLHFN_02344	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PFLHLHFN_02345	3.88e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PFLHLHFN_02346	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PFLHLHFN_02347	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PFLHLHFN_02348	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PFLHLHFN_02349	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PFLHLHFN_02350	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PFLHLHFN_02351	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PFLHLHFN_02352	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
PFLHLHFN_02353	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PFLHLHFN_02354	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
PFLHLHFN_02355	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PFLHLHFN_02356	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PFLHLHFN_02357	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PFLHLHFN_02358	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PFLHLHFN_02359	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PFLHLHFN_02360	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PFLHLHFN_02361	2.91e-67	-	-	-	-	-	-	-	-
PFLHLHFN_02362	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PFLHLHFN_02363	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PFLHLHFN_02364	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFLHLHFN_02365	8.53e-59	-	-	-	-	-	-	-	-
PFLHLHFN_02366	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
PFLHLHFN_02367	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PFLHLHFN_02368	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
PFLHLHFN_02369	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PFLHLHFN_02370	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PFLHLHFN_02371	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PFLHLHFN_02372	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFLHLHFN_02373	4.1e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PFLHLHFN_02374	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PFLHLHFN_02375	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PFLHLHFN_02376	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PFLHLHFN_02377	5.98e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PFLHLHFN_02378	1.35e-56	-	-	-	-	-	-	-	-
PFLHLHFN_02379	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
PFLHLHFN_02380	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PFLHLHFN_02381	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PFLHLHFN_02382	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PFLHLHFN_02383	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PFLHLHFN_02384	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PFLHLHFN_02385	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PFLHLHFN_02386	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PFLHLHFN_02387	1.04e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PFLHLHFN_02388	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PFLHLHFN_02389	3.24e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFLHLHFN_02390	2.57e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PFLHLHFN_02391	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFLHLHFN_02392	1.01e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PFLHLHFN_02393	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PFLHLHFN_02394	1.36e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PFLHLHFN_02395	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PFLHLHFN_02396	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PFLHLHFN_02397	9.98e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PFLHLHFN_02398	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PFLHLHFN_02401	3.94e-250	ampC	-	-	V	-	-	-	Beta-lactamase
PFLHLHFN_02402	4.63e-274	-	-	-	EGP	-	-	-	Major Facilitator
PFLHLHFN_02403	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PFLHLHFN_02404	1.52e-136	vanZ	-	-	V	-	-	-	VanZ like family
PFLHLHFN_02405	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFLHLHFN_02406	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PFLHLHFN_02407	4.96e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PFLHLHFN_02408	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
PFLHLHFN_02409	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PFLHLHFN_02410	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PFLHLHFN_02411	3e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PFLHLHFN_02412	3.68e-14	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PFLHLHFN_02413	6.88e-11	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
PFLHLHFN_02415	7.88e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)