ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PHKHPGGK_00001 4.14e-113 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
PHKHPGGK_00002 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
PHKHPGGK_00003 3.61e-60 - - - - - - - -
PHKHPGGK_00004 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHKHPGGK_00006 3.75e-48 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_00007 6.55e-97 - - - - - - - -
PHKHPGGK_00008 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHKHPGGK_00009 2.63e-194 int3 - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_00011 6.66e-31 - - - K - - - Helix-turn-helix domain
PHKHPGGK_00012 4.74e-30 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
PHKHPGGK_00013 7.62e-41 - - - K - - - Helix-turn-helix domain
PHKHPGGK_00014 2.38e-32 - - - S - - - Domain of unknown function (DUF771)
PHKHPGGK_00019 1.47e-303 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PHKHPGGK_00020 3.46e-32 - - - S - - - Alpha beta hydrolase
PHKHPGGK_00021 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
PHKHPGGK_00022 4.29e-137 ybbB - - S - - - Protein of unknown function (DUF1211)
PHKHPGGK_00023 6.73e-78 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHKHPGGK_00024 2.16e-79 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHKHPGGK_00025 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
PHKHPGGK_00026 3.76e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_00028 1.62e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHKHPGGK_00029 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
PHKHPGGK_00030 1.79e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
PHKHPGGK_00031 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
PHKHPGGK_00032 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PHKHPGGK_00033 2.43e-196 - - - I - - - Alpha/beta hydrolase family
PHKHPGGK_00034 2.09e-105 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
PHKHPGGK_00035 1.91e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PHKHPGGK_00036 3.09e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PHKHPGGK_00037 3.05e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PHKHPGGK_00038 3.68e-176 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PHKHPGGK_00040 9.91e-150 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
PHKHPGGK_00041 9.67e-104 - - - - - - - -
PHKHPGGK_00042 6.74e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
PHKHPGGK_00043 1.68e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PHKHPGGK_00044 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHKHPGGK_00045 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
PHKHPGGK_00046 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHKHPGGK_00047 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
PHKHPGGK_00048 1.92e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHKHPGGK_00049 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
PHKHPGGK_00050 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
PHKHPGGK_00051 1.66e-116 ypmB - - S - - - Protein conserved in bacteria
PHKHPGGK_00052 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PHKHPGGK_00053 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PHKHPGGK_00054 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHKHPGGK_00055 3.02e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
PHKHPGGK_00056 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
PHKHPGGK_00057 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
PHKHPGGK_00058 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHKHPGGK_00059 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PHKHPGGK_00060 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
PHKHPGGK_00061 4.4e-215 - - - - - - - -
PHKHPGGK_00062 4.01e-184 - - - - - - - -
PHKHPGGK_00063 1.27e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PHKHPGGK_00064 3.49e-36 - - - - - - - -
PHKHPGGK_00065 3.85e-193 - - - - - - - -
PHKHPGGK_00066 2.54e-176 - - - - - - - -
PHKHPGGK_00067 1.65e-180 - - - - - - - -
PHKHPGGK_00068 1.33e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHKHPGGK_00069 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
PHKHPGGK_00070 2.86e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PHKHPGGK_00071 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHKHPGGK_00072 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PHKHPGGK_00073 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
PHKHPGGK_00074 4.34e-166 - - - S - - - Peptidase family M23
PHKHPGGK_00075 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHKHPGGK_00076 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHKHPGGK_00077 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PHKHPGGK_00078 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PHKHPGGK_00079 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PHKHPGGK_00080 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHKHPGGK_00081 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHKHPGGK_00082 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
PHKHPGGK_00083 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
PHKHPGGK_00084 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PHKHPGGK_00085 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PHKHPGGK_00086 1.34e-22 - - - S - - - CRISPR-associated protein (Cas_Csn2)
PHKHPGGK_00087 1.83e-54 - - - C - - - FMN_bind
PHKHPGGK_00088 4.49e-108 - - - - - - - -
PHKHPGGK_00089 3.14e-226 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
PHKHPGGK_00090 2.06e-111 alkD - - L - - - DNA alkylation repair enzyme
PHKHPGGK_00091 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHKHPGGK_00092 3.54e-94 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
PHKHPGGK_00093 1.43e-309 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHKHPGGK_00094 7.68e-63 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
PHKHPGGK_00095 5.01e-150 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
PHKHPGGK_00096 6.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
PHKHPGGK_00097 7.73e-199 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PHKHPGGK_00098 9.46e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
PHKHPGGK_00099 5.51e-35 - - - - - - - -
PHKHPGGK_00100 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
PHKHPGGK_00101 6.13e-70 - - - K - - - sequence-specific DNA binding
PHKHPGGK_00102 5.97e-55 - - - S - - - SnoaL-like domain
PHKHPGGK_00103 0.0 - - - L - - - PLD-like domain
PHKHPGGK_00105 7.56e-230 - - - L - - - N-6 DNA Methylase
PHKHPGGK_00106 1.49e-47 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00107 6.57e-45 - - - S - - - Phage derived protein Gp49-like (DUF891)
PHKHPGGK_00111 4.36e-46 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
PHKHPGGK_00112 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
PHKHPGGK_00113 2.52e-06 - - - D - - - Domain of Unknown Function (DUF1542)
PHKHPGGK_00114 0.0 qacA - - EGP - - - Major Facilitator
PHKHPGGK_00115 1.02e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHKHPGGK_00116 3.34e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
PHKHPGGK_00117 3.55e-28 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
PHKHPGGK_00118 2.33e-230 pepA - - E - - - M42 glutamyl aminopeptidase
PHKHPGGK_00119 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
PHKHPGGK_00120 6.07e-223 ydhF - - S - - - Aldo keto reductase
PHKHPGGK_00121 1.53e-176 - - - - - - - -
PHKHPGGK_00122 1.11e-256 steT - - E ko:K03294 - ko00000 amino acid
PHKHPGGK_00123 3.97e-33 steT - - E ko:K03294 - ko00000 amino acid
PHKHPGGK_00124 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
PHKHPGGK_00125 1.07e-165 - - - F - - - glutamine amidotransferase
PHKHPGGK_00126 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHKHPGGK_00127 2.53e-106 - - - K - - - Transcriptional regulator, MarR family
PHKHPGGK_00128 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00129 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
PHKHPGGK_00130 1.72e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PHKHPGGK_00131 8.41e-314 - - - G - - - MFS/sugar transport protein
PHKHPGGK_00132 5.43e-50 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
PHKHPGGK_00133 2.72e-60 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
PHKHPGGK_00134 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00135 3.39e-187 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00136 4.29e-122 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00137 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00138 1.04e-211 - - - S - - - Protein of unknown function (DUF2974)
PHKHPGGK_00139 2.09e-110 - - - - - - - -
PHKHPGGK_00140 3.52e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
PHKHPGGK_00141 2.2e-308 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHKHPGGK_00142 7.29e-209 - - - C - - - Domain of unknown function (DUF4931)
PHKHPGGK_00143 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHKHPGGK_00144 2.59e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHKHPGGK_00145 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHKHPGGK_00146 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
PHKHPGGK_00147 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
PHKHPGGK_00148 3.18e-198 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
PHKHPGGK_00149 2.9e-79 - - - S - - - Enterocin A Immunity
PHKHPGGK_00150 4.44e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
PHKHPGGK_00151 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
PHKHPGGK_00152 1.85e-205 - - - S - - - Phospholipase, patatin family
PHKHPGGK_00153 7.44e-189 - - - S - - - hydrolase
PHKHPGGK_00154 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
PHKHPGGK_00155 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PHKHPGGK_00156 1.52e-103 - - - - - - - -
PHKHPGGK_00157 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHKHPGGK_00158 1.76e-52 - - - - - - - -
PHKHPGGK_00159 2.14e-154 - - - C - - - nitroreductase
PHKHPGGK_00160 0.0 yhdP - - S - - - Transporter associated domain
PHKHPGGK_00161 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
PHKHPGGK_00162 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHKHPGGK_00163 1.73e-114 - - - L - - - PFAM transposase, IS4 family protein
PHKHPGGK_00164 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
PHKHPGGK_00165 1.93e-268 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHKHPGGK_00166 7.32e-157 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHKHPGGK_00167 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PHKHPGGK_00168 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
PHKHPGGK_00169 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PHKHPGGK_00170 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PHKHPGGK_00171 4.77e-248 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
PHKHPGGK_00172 1.28e-226 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_00173 1.86e-91 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_00174 7.09e-172 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_00175 2.36e-217 degV1 - - S - - - DegV family
PHKHPGGK_00176 1.94e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
PHKHPGGK_00177 1.32e-171 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
PHKHPGGK_00178 1.45e-36 - - - S - - - Peptidase propeptide and YPEB domain
PHKHPGGK_00179 1.73e-79 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
PHKHPGGK_00180 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_00181 8.83e-170 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHKHPGGK_00182 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHKHPGGK_00183 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHKHPGGK_00185 1.12e-28 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
PHKHPGGK_00186 1.74e-33 - - - K - - - Helix-turn-helix domain
PHKHPGGK_00188 1.85e-112 int3 - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_00192 1.5e-93 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHKHPGGK_00193 2.47e-104 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHKHPGGK_00194 1.44e-164 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHKHPGGK_00195 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHKHPGGK_00196 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
PHKHPGGK_00197 0.0 ycaM - - E - - - amino acid
PHKHPGGK_00198 0.0 - - - - - - - -
PHKHPGGK_00200 9.26e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
PHKHPGGK_00201 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHKHPGGK_00202 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PHKHPGGK_00203 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHKHPGGK_00204 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
PHKHPGGK_00205 3.07e-124 - - - - - - - -
PHKHPGGK_00206 2.81e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHKHPGGK_00207 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHKHPGGK_00208 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
PHKHPGGK_00209 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
PHKHPGGK_00210 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PHKHPGGK_00211 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
PHKHPGGK_00212 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHKHPGGK_00213 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00214 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00215 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHKHPGGK_00216 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHKHPGGK_00217 1.6e-220 ybbR - - S - - - YbbR-like protein
PHKHPGGK_00218 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHKHPGGK_00219 8.04e-190 - - - S - - - hydrolase
PHKHPGGK_00220 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
PHKHPGGK_00221 2.85e-153 - - - - - - - -
PHKHPGGK_00222 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHKHPGGK_00223 1.25e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PHKHPGGK_00224 3.42e-194 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
PHKHPGGK_00225 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHKHPGGK_00226 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHKHPGGK_00227 5.12e-199 ybcH - - D ko:K06889 - ko00000 Alpha beta
PHKHPGGK_00228 6.91e-118 - - - T - - - Putative diguanylate phosphodiesterase
PHKHPGGK_00229 2.21e-34 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
PHKHPGGK_00230 1.67e-136 icaA - - M - - - Glycosyl transferase family group 2
PHKHPGGK_00231 2.64e-46 - - - - - - - -
PHKHPGGK_00232 1.96e-110 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
PHKHPGGK_00233 1.14e-99 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHKHPGGK_00235 0.0 - - - E - - - Amino acid permease
PHKHPGGK_00236 4.53e-11 - - - - - - - -
PHKHPGGK_00237 1.02e-75 - - - - - - - -
PHKHPGGK_00238 2.62e-69 - - - - - - - -
PHKHPGGK_00240 4.4e-165 - - - S - - - PAS domain
PHKHPGGK_00241 4.64e-63 - - - S - - - Domain of unknown function (DUF4811)
PHKHPGGK_00242 5.76e-292 ycnB - - U - - - Belongs to the major facilitator superfamily
PHKHPGGK_00243 4.36e-27 ycnB - - U - - - Belongs to the major facilitator superfamily
PHKHPGGK_00244 7.65e-101 - - - K - - - MerR HTH family regulatory protein
PHKHPGGK_00245 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
PHKHPGGK_00246 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
PHKHPGGK_00247 1.69e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
PHKHPGGK_00248 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHKHPGGK_00249 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
PHKHPGGK_00250 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
PHKHPGGK_00251 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PHKHPGGK_00252 0.0 - - - S - - - Calcineurin-like phosphoesterase
PHKHPGGK_00253 5.18e-109 - - - - - - - -
PHKHPGGK_00254 6.82e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
PHKHPGGK_00255 1.83e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_00256 1.02e-154 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_00257 1.67e-175 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PHKHPGGK_00258 8.61e-202 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
PHKHPGGK_00259 9.29e-111 usp5 - - T - - - universal stress protein
PHKHPGGK_00260 1.24e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHKHPGGK_00261 3.77e-113 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_00262 4.83e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
PHKHPGGK_00264 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
PHKHPGGK_00265 8.82e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHKHPGGK_00266 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
PHKHPGGK_00267 2.7e-199 - - - I - - - alpha/beta hydrolase fold
PHKHPGGK_00268 7.8e-167 yibF - - S - - - overlaps another CDS with the same product name
PHKHPGGK_00269 1.69e-258 yibE - - S - - - overlaps another CDS with the same product name
PHKHPGGK_00270 2.45e-164 - - - - - - - -
PHKHPGGK_00271 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PHKHPGGK_00272 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
PHKHPGGK_00273 1.01e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00274 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00275 1.11e-177 - - - - - - - -
PHKHPGGK_00276 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
PHKHPGGK_00277 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHKHPGGK_00278 2.32e-47 - - - - - - - -
PHKHPGGK_00279 3.82e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PHKHPGGK_00280 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
PHKHPGGK_00281 1.64e-45 - - - - - - - -
PHKHPGGK_00282 6.09e-121 - - - - - - - -
PHKHPGGK_00284 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
PHKHPGGK_00285 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PHKHPGGK_00286 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHKHPGGK_00287 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PHKHPGGK_00288 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHKHPGGK_00289 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
PHKHPGGK_00290 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
PHKHPGGK_00291 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
PHKHPGGK_00292 0.0 - - - S - - - membrane
PHKHPGGK_00293 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PHKHPGGK_00294 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PHKHPGGK_00295 7.92e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHKHPGGK_00296 3.25e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
PHKHPGGK_00297 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
PHKHPGGK_00298 4.95e-89 yqhL - - P - - - Rhodanese-like protein
PHKHPGGK_00299 3.84e-216 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHKHPGGK_00300 2.05e-286 ynbB - - P - - - aluminum resistance
PHKHPGGK_00301 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PHKHPGGK_00302 2.37e-219 - - - - - - - -
PHKHPGGK_00303 2.09e-205 - - - - - - - -
PHKHPGGK_00307 6.78e-47 - - - - - - - -
PHKHPGGK_00308 1.44e-161 - - - S - - - interspecies interaction between organisms
PHKHPGGK_00309 1.28e-09 - - - S - - - PFAM HicB family
PHKHPGGK_00310 2.86e-13 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
PHKHPGGK_00311 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_00312 1.57e-84 - - - K - - - Helix-turn-helix domain, rpiR family
PHKHPGGK_00313 2.65e-154 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PHKHPGGK_00314 1.03e-112 nanK - - GK - - - ROK family
PHKHPGGK_00315 3.74e-70 - - - G - - - Xylose isomerase domain protein TIM barrel
PHKHPGGK_00316 1.48e-166 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHKHPGGK_00317 6.48e-279 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PHKHPGGK_00318 1.4e-74 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PHKHPGGK_00319 2.58e-17 axe1 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 acetyl xylan esterase
PHKHPGGK_00320 6.9e-141 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PHKHPGGK_00321 2.58e-13 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHKHPGGK_00322 1.59e-108 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHKHPGGK_00323 1.8e-142 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
PHKHPGGK_00324 4.11e-150 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00325 1.89e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00326 1.02e-67 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00327 8.08e-117 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00328 9.4e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PHKHPGGK_00329 9.11e-110 - - - C - - - Aldo keto reductase
PHKHPGGK_00330 9.44e-63 - - - M - - - LysM domain protein
PHKHPGGK_00331 1.8e-36 - - - M - - - LysM domain protein
PHKHPGGK_00333 2.86e-169 - - - L - - - Transposase and inactivated derivatives
PHKHPGGK_00335 3.31e-65 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
PHKHPGGK_00340 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHKHPGGK_00341 1.71e-128 treR - - K ko:K03486 - ko00000,ko03000 UTRA
PHKHPGGK_00342 2.02e-137 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHKHPGGK_00343 3e-219 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHKHPGGK_00344 1.12e-85 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHKHPGGK_00345 3.95e-242 - - - L ko:K07478 - ko00000 AAA C-terminal domain
PHKHPGGK_00346 2.71e-16 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PHKHPGGK_00347 9.42e-267 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PHKHPGGK_00348 3.45e-109 - - - K - - - Acetyltransferase (GNAT) domain
PHKHPGGK_00349 2.28e-291 - - - S - - - Putative peptidoglycan binding domain
PHKHPGGK_00350 7.89e-124 - - - S - - - ECF-type riboflavin transporter, S component
PHKHPGGK_00351 6.55e-129 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
PHKHPGGK_00352 9.19e-259 pbpX1 - - V - - - Beta-lactamase
PHKHPGGK_00353 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
PHKHPGGK_00354 3.21e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHKHPGGK_00355 1.2e-147 - - - I - - - Acid phosphatase homologues
PHKHPGGK_00356 9.17e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
PHKHPGGK_00357 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
PHKHPGGK_00358 7.27e-106 - - - C - - - Flavodoxin
PHKHPGGK_00359 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
PHKHPGGK_00360 2.88e-310 ynbB - - P - - - aluminum resistance
PHKHPGGK_00361 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
PHKHPGGK_00362 0.0 - - - E - - - Amino acid permease
PHKHPGGK_00363 7.88e-121 - - - C - - - Pyridoxamine 5'-phosphate oxidase
PHKHPGGK_00364 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
PHKHPGGK_00365 3.03e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PHKHPGGK_00366 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
PHKHPGGK_00367 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHKHPGGK_00368 7.64e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHKHPGGK_00369 2.15e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
PHKHPGGK_00370 1.1e-96 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHKHPGGK_00371 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHKHPGGK_00372 8.34e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00374 1.28e-162 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
PHKHPGGK_00376 2.64e-103 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
PHKHPGGK_00377 1.68e-199 - - - M - - - Glycosyltransferase
PHKHPGGK_00378 1.1e-153 epsE2 - - M - - - Bacterial sugar transferase
PHKHPGGK_00379 6.64e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
PHKHPGGK_00380 6.84e-161 ywqD - - D - - - Capsular exopolysaccharide family
PHKHPGGK_00381 3.05e-184 epsB - - M - - - biosynthesis protein
PHKHPGGK_00382 1.47e-243 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHKHPGGK_00386 7.5e-282 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHKHPGGK_00387 1.26e-223 - - - S - - - Cysteine-rich secretory protein family
PHKHPGGK_00388 3.01e-54 - - - - - - - -
PHKHPGGK_00389 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
PHKHPGGK_00390 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
PHKHPGGK_00391 1.47e-114 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
PHKHPGGK_00392 4.26e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
PHKHPGGK_00393 3.72e-55 - - - - - - - -
PHKHPGGK_00394 0.0 - - - S - - - O-antigen ligase like membrane protein
PHKHPGGK_00395 8.77e-144 - - - - - - - -
PHKHPGGK_00396 5.48e-283 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
PHKHPGGK_00397 4.75e-101 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
PHKHPGGK_00398 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHKHPGGK_00399 1.16e-101 - - - - - - - -
PHKHPGGK_00400 1.58e-143 - - - S - - - Peptidase_C39 like family
PHKHPGGK_00401 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
PHKHPGGK_00402 7.35e-174 - - - S - - - Putative threonine/serine exporter
PHKHPGGK_00403 0.0 - - - S - - - ABC transporter
PHKHPGGK_00404 2.52e-76 - - - - - - - -
PHKHPGGK_00405 8.69e-93 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHKHPGGK_00406 5.49e-46 - - - - - - - -
PHKHPGGK_00407 7.2e-40 - - - - - - - -
PHKHPGGK_00408 2.33e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PHKHPGGK_00409 5.74e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHKHPGGK_00410 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PHKHPGGK_00411 7.27e-42 - - - - - - - -
PHKHPGGK_00412 1.47e-91 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
PHKHPGGK_00415 4.61e-37 - - - S - - - Enterocin A Immunity
PHKHPGGK_00417 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHKHPGGK_00420 4.19e-92 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PHKHPGGK_00421 1.41e-37 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_00422 2.35e-117 - - - F - - - Nucleoside 2-deoxyribosyltransferase
PHKHPGGK_00423 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PHKHPGGK_00425 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHKHPGGK_00426 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PHKHPGGK_00427 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHKHPGGK_00428 2.14e-231 - - - M - - - CHAP domain
PHKHPGGK_00429 2.79e-102 - - - - - - - -
PHKHPGGK_00430 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHKHPGGK_00431 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHKHPGGK_00432 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHKHPGGK_00433 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHKHPGGK_00434 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHKHPGGK_00435 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHKHPGGK_00436 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
PHKHPGGK_00437 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHKHPGGK_00438 1.74e-274 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHKHPGGK_00439 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
PHKHPGGK_00440 1.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHKHPGGK_00441 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHKHPGGK_00442 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
PHKHPGGK_00443 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHKHPGGK_00444 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
PHKHPGGK_00445 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHKHPGGK_00446 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PHKHPGGK_00447 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHKHPGGK_00448 5.58e-92 yslB - - S - - - Protein of unknown function (DUF2507)
PHKHPGGK_00449 1.68e-185 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PHKHPGGK_00450 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHKHPGGK_00451 1.55e-29 - - - - - - - -
PHKHPGGK_00452 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
PHKHPGGK_00453 4.1e-34 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PHKHPGGK_00454 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_00455 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHKHPGGK_00456 5.26e-171 - - - H - - - Aldolase/RraA
PHKHPGGK_00457 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PHKHPGGK_00458 2.07e-178 - - - P - - - Voltage gated chloride channel
PHKHPGGK_00459 3.44e-238 - - - C - - - FMN-dependent dehydrogenase
PHKHPGGK_00460 1.05e-69 - - - - - - - -
PHKHPGGK_00461 7.17e-56 - - - - - - - -
PHKHPGGK_00462 2.21e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHKHPGGK_00463 0.0 - - - E - - - amino acid
PHKHPGGK_00464 3.87e-199 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHKHPGGK_00465 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
PHKHPGGK_00466 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PHKHPGGK_00467 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHKHPGGK_00468 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHKHPGGK_00469 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHKHPGGK_00470 2.3e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHKHPGGK_00471 3.54e-166 - - - S - - - (CBS) domain
PHKHPGGK_00472 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PHKHPGGK_00473 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHKHPGGK_00474 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHKHPGGK_00475 7.32e-46 yabO - - J - - - S4 domain protein
PHKHPGGK_00476 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PHKHPGGK_00477 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
PHKHPGGK_00478 1.36e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHKHPGGK_00479 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHKHPGGK_00480 1.37e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHKHPGGK_00481 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHKHPGGK_00482 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PHKHPGGK_00483 2.84e-108 - - - K - - - FR47-like protein
PHKHPGGK_00492 2.72e-35 - - - S - - - Domain of unknown function (DUF771)
PHKHPGGK_00494 3.51e-96 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
PHKHPGGK_00495 2.93e-195 - - - - - - - -
PHKHPGGK_00496 6.16e-14 - - - - - - - -
PHKHPGGK_00502 8.52e-25 lysM - - M - - - LysM domain
PHKHPGGK_00503 6.51e-194 - - - S - - - COG0433 Predicted ATPase
PHKHPGGK_00507 2.66e-165 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
PHKHPGGK_00512 3.24e-13 - - - S - - - SLAP domain
PHKHPGGK_00513 8.5e-10 - - - M - - - oxidoreductase activity
PHKHPGGK_00515 6.95e-21 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PHKHPGGK_00516 3.37e-15 - - - S - - - SLAP domain
PHKHPGGK_00522 3.35e-55 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00523 3.74e-182 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_00524 7.92e-221 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00525 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHKHPGGK_00526 1.21e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHKHPGGK_00527 7.32e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHKHPGGK_00528 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHKHPGGK_00529 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHKHPGGK_00530 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
PHKHPGGK_00531 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
PHKHPGGK_00532 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PHKHPGGK_00533 1.13e-115 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
PHKHPGGK_00534 5.77e-39 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
PHKHPGGK_00542 1.61e-155 - - - S - - - Phage minor structural protein
PHKHPGGK_00544 7.57e-134 - - - L - - - Phage tail tape measure protein TP901
PHKHPGGK_00552 6.39e-66 - - - S - - - Phage capsid family
PHKHPGGK_00553 2.93e-108 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
PHKHPGGK_00554 3.53e-168 - - - S - - - Phage portal protein
PHKHPGGK_00556 0.0 - - - S - - - Phage Terminase
PHKHPGGK_00559 1.21e-74 - - - S - - - Phage terminase, small subunit
PHKHPGGK_00560 1.34e-62 - - - L - - - HNH nucleases
PHKHPGGK_00565 3.85e-49 - - - S - - - VRR_NUC
PHKHPGGK_00576 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
PHKHPGGK_00577 1.41e-23 - - - S - - - Protein of unknown function (DUF669)
PHKHPGGK_00578 1.07e-182 - - - L - - - Helicase C-terminal domain protein
PHKHPGGK_00580 8.83e-88 - - - S - - - AAA domain
PHKHPGGK_00586 5.99e-61 - - - - - - - -
PHKHPGGK_00587 1.23e-101 - - - S - - - Phage antirepressor protein KilAC domain
PHKHPGGK_00588 2.69e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00589 2.15e-09 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00592 8.76e-146 int3 - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_00593 2.29e-41 - - - - - - - -
PHKHPGGK_00594 1.1e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PHKHPGGK_00595 7.49e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PHKHPGGK_00596 1.71e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHKHPGGK_00597 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PHKHPGGK_00598 3.28e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PHKHPGGK_00599 7.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHKHPGGK_00600 1.27e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHKHPGGK_00601 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHKHPGGK_00602 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHKHPGGK_00603 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PHKHPGGK_00604 2.19e-100 - - - S - - - ASCH
PHKHPGGK_00605 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PHKHPGGK_00606 7.22e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
PHKHPGGK_00607 6.44e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHKHPGGK_00608 1.53e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHKHPGGK_00609 1.97e-248 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHKHPGGK_00610 7.19e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHKHPGGK_00611 2.78e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHKHPGGK_00612 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
PHKHPGGK_00613 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHKHPGGK_00614 1.75e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
PHKHPGGK_00615 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PHKHPGGK_00616 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PHKHPGGK_00617 5.24e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHKHPGGK_00618 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
PHKHPGGK_00620 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
PHKHPGGK_00621 0.0 - - - S - - - Predicted membrane protein (DUF2207)
PHKHPGGK_00622 8.21e-200 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
PHKHPGGK_00623 4.73e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHKHPGGK_00625 1.23e-227 lipA - - I - - - Carboxylesterase family
PHKHPGGK_00626 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PHKHPGGK_00627 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
PHKHPGGK_00628 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
PHKHPGGK_00629 1.13e-155 supH - - S - - - haloacid dehalogenase-like hydrolase
PHKHPGGK_00632 8.77e-220 - - - M - - - Glycosyl hydrolases family 25
PHKHPGGK_00633 2.16e-39 - - - - - - - -
PHKHPGGK_00634 6.31e-27 - - - - - - - -
PHKHPGGK_00637 1.75e-26 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
PHKHPGGK_00638 4.37e-38 - - - - - - - -
PHKHPGGK_00646 3.57e-141 - - - S - - - Baseplate J-like protein
PHKHPGGK_00647 1.55e-40 - - - - - - - -
PHKHPGGK_00648 1.66e-48 - - - - - - - -
PHKHPGGK_00649 2.15e-126 - - - - - - - -
PHKHPGGK_00650 1.62e-59 - - - - - - - -
PHKHPGGK_00651 4.24e-53 - - - M - - - LysM domain
PHKHPGGK_00652 1.13e-236 - - - L - - - Phage tail tape measure protein TP901
PHKHPGGK_00655 1.2e-167 - - - S - - - Protein of unknown function (DUF3383)
PHKHPGGK_00658 6.61e-24 - - - - - - - -
PHKHPGGK_00659 2.36e-37 - - - S - - - Protein of unknown function (DUF4054)
PHKHPGGK_00661 8.98e-25 - - - - - - - -
PHKHPGGK_00662 5.02e-70 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
PHKHPGGK_00663 2.36e-27 - - - S - - - Lysin motif
PHKHPGGK_00664 5.57e-69 - - - S - - - Phage Mu protein F like protein
PHKHPGGK_00665 1.16e-110 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
PHKHPGGK_00666 4.27e-234 - - - S - - - Terminase-like family
PHKHPGGK_00669 9.77e-27 - - - S - - - N-methyltransferase activity
PHKHPGGK_00677 3.69e-15 - - - S - - - VRR_NUC
PHKHPGGK_00679 7.58e-90 - - - S - - - ORF6C domain
PHKHPGGK_00684 5.95e-24 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PHKHPGGK_00686 2.8e-38 - - - K - - - Helix-turn-helix domain
PHKHPGGK_00687 4.86e-54 - - - S - - - ERF superfamily
PHKHPGGK_00688 4.51e-65 - - - S - - - Protein of unknown function (DUF1351)
PHKHPGGK_00696 6.19e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00697 7.75e-24 - - - S - - - protein disulfide oxidoreductase activity
PHKHPGGK_00699 3.93e-05 - - - - - - - -
PHKHPGGK_00700 2.73e-112 - - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_00701 2.93e-16 supH - - S - - - haloacid dehalogenase-like hydrolase
PHKHPGGK_00702 4.3e-66 - - - - - - - -
PHKHPGGK_00703 8.51e-50 - - - - - - - -
PHKHPGGK_00704 2.48e-80 - - - S - - - Alpha beta hydrolase
PHKHPGGK_00705 6.78e-24 - - - S - - - Alpha beta hydrolase
PHKHPGGK_00706 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHKHPGGK_00707 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PHKHPGGK_00708 8.74e-62 - - - - - - - -
PHKHPGGK_00709 6.79e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
PHKHPGGK_00710 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PHKHPGGK_00711 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
PHKHPGGK_00712 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PHKHPGGK_00713 8.31e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHKHPGGK_00714 3.68e-230 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PHKHPGGK_00715 2.9e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHKHPGGK_00716 8.81e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHKHPGGK_00717 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHKHPGGK_00718 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHKHPGGK_00719 4.37e-132 - - - GM - - - NmrA-like family
PHKHPGGK_00720 5.08e-229 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
PHKHPGGK_00721 5.83e-24 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
PHKHPGGK_00722 4.36e-93 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PHKHPGGK_00723 3.23e-59 - - - - - - - -
PHKHPGGK_00724 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
PHKHPGGK_00725 1.23e-242 - - - S - - - TerB-C domain
PHKHPGGK_00726 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
PHKHPGGK_00727 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
PHKHPGGK_00728 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00729 9.05e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
PHKHPGGK_00730 3.36e-42 - - - - - - - -
PHKHPGGK_00731 1.78e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PHKHPGGK_00732 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PHKHPGGK_00733 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
PHKHPGGK_00734 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_00735 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHKHPGGK_00736 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
PHKHPGGK_00737 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHKHPGGK_00738 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
PHKHPGGK_00739 4.47e-58 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
PHKHPGGK_00740 7.99e-309 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
PHKHPGGK_00741 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
PHKHPGGK_00742 2.07e-203 - - - K - - - Transcriptional regulator
PHKHPGGK_00743 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
PHKHPGGK_00744 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
PHKHPGGK_00745 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
PHKHPGGK_00746 2.72e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
PHKHPGGK_00748 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
PHKHPGGK_00749 5.94e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
PHKHPGGK_00750 8.97e-47 - - - - - - - -
PHKHPGGK_00752 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
PHKHPGGK_00753 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
PHKHPGGK_00754 1.14e-164 terC - - P - - - Integral membrane protein TerC family
PHKHPGGK_00755 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
PHKHPGGK_00756 1.41e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PHKHPGGK_00757 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00758 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00759 1.4e-191 yhaH - - S - - - Protein of unknown function (DUF805)
PHKHPGGK_00760 2.42e-204 - - - L - - - HNH nucleases
PHKHPGGK_00761 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
PHKHPGGK_00762 3.67e-225 - - - G - - - Glycosyl hydrolases family 8
PHKHPGGK_00763 4.75e-239 - - - M - - - Glycosyl transferase
PHKHPGGK_00764 1.34e-09 - - - S - - - Uncharacterised protein family (UPF0236)
PHKHPGGK_00765 9.69e-25 - - - - - - - -
PHKHPGGK_00766 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
PHKHPGGK_00767 3.34e-92 - - - S - - - Iron-sulphur cluster biosynthesis
PHKHPGGK_00768 7.23e-244 ysdE - - P - - - Citrate transporter
PHKHPGGK_00769 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
PHKHPGGK_00770 1.16e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PHKHPGGK_00771 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
PHKHPGGK_00772 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00773 1.19e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PHKHPGGK_00774 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
PHKHPGGK_00775 6.67e-115 - - - G - - - Peptidase_C39 like family
PHKHPGGK_00776 2.16e-207 - - - M - - - NlpC/P60 family
PHKHPGGK_00777 1.93e-32 - - - G - - - Peptidase_C39 like family
PHKHPGGK_00778 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
PHKHPGGK_00779 2.96e-176 - - - V - - - N-6 DNA Methylase
PHKHPGGK_00780 3.48e-105 - - - V - - - Type I restriction modification DNA specificity domain
PHKHPGGK_00781 6.14e-107 - - - - - - - -
PHKHPGGK_00782 1.67e-95 - - - K - - - Transcriptional regulator, MarR family
PHKHPGGK_00783 8.44e-65 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PHKHPGGK_00784 9.89e-112 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHKHPGGK_00785 1.98e-47 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHKHPGGK_00786 4.22e-41 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHKHPGGK_00787 2.77e-177 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
PHKHPGGK_00788 1.4e-137 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PHKHPGGK_00789 2.53e-268 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHKHPGGK_00790 3.17e-67 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHKHPGGK_00791 7.28e-80 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PHKHPGGK_00792 3.44e-300 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
PHKHPGGK_00793 4.9e-180 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHKHPGGK_00794 2.42e-163 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
PHKHPGGK_00795 1.9e-158 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PHKHPGGK_00796 7.01e-103 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHKHPGGK_00797 2.27e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHKHPGGK_00798 1.44e-07 - - - S - - - YSIRK type signal peptide
PHKHPGGK_00800 1.2e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PHKHPGGK_00801 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
PHKHPGGK_00802 9.56e-274 - - - L - - - Helicase C-terminal domain protein
PHKHPGGK_00803 0.0 - - - L - - - Helicase C-terminal domain protein
PHKHPGGK_00804 6.72e-261 pbpX - - V - - - Beta-lactamase
PHKHPGGK_00805 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
PHKHPGGK_00806 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHKHPGGK_00807 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
PHKHPGGK_00808 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
PHKHPGGK_00809 9e-132 - - - L - - - Integrase
PHKHPGGK_00810 1e-131 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHKHPGGK_00811 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHKHPGGK_00812 3.66e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PHKHPGGK_00813 1.74e-248 - - - G - - - Transmembrane secretion effector
PHKHPGGK_00814 5.63e-171 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_00815 3.65e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
PHKHPGGK_00816 1.83e-91 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_00817 6.69e-84 - - - L - - - RelB antitoxin
PHKHPGGK_00818 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
PHKHPGGK_00819 8.6e-108 - - - M - - - NlpC/P60 family
PHKHPGGK_00822 1.02e-200 - - - - - - - -
PHKHPGGK_00823 1.03e-07 - - - - - - - -
PHKHPGGK_00824 5.51e-47 - - - - - - - -
PHKHPGGK_00825 4.48e-206 - - - EG - - - EamA-like transporter family
PHKHPGGK_00826 3.18e-209 - - - EG - - - EamA-like transporter family
PHKHPGGK_00827 1.07e-177 yicL - - EG - - - EamA-like transporter family
PHKHPGGK_00828 1.32e-137 - - - - - - - -
PHKHPGGK_00829 9.07e-143 - - - - - - - -
PHKHPGGK_00830 1.84e-238 - - - S - - - DUF218 domain
PHKHPGGK_00831 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
PHKHPGGK_00832 6.77e-111 - - - - - - - -
PHKHPGGK_00833 1.09e-74 - - - - - - - -
PHKHPGGK_00834 7.26e-35 - - - S - - - Protein conserved in bacteria
PHKHPGGK_00835 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
PHKHPGGK_00836 1.01e-38 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
PHKHPGGK_00837 3.87e-73 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHKHPGGK_00838 1.48e-136 - - - L - - - PFAM Integrase catalytic
PHKHPGGK_00839 1.44e-57 eriC - - P ko:K03281 - ko00000 chloride
PHKHPGGK_00841 3.74e-180 - - - EGP - - - Major Facilitator Superfamily
PHKHPGGK_00842 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
PHKHPGGK_00843 0.0 fusA1 - - J - - - elongation factor G
PHKHPGGK_00844 9.52e-205 yvgN - - C - - - Aldo keto reductase
PHKHPGGK_00845 5.49e-97 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHKHPGGK_00846 7.93e-63 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHKHPGGK_00847 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHKHPGGK_00848 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
PHKHPGGK_00849 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHKHPGGK_00850 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00851 8.58e-60 - - - - - - - -
PHKHPGGK_00852 3.56e-85 - - - S - - - SLAP domain
PHKHPGGK_00853 1.08e-79 - - - S - - - Bacteriocin helveticin-J
PHKHPGGK_00854 7.61e-59 - - - - - - - -
PHKHPGGK_00855 1.53e-54 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_00856 2.81e-102 - - - E - - - Zn peptidase
PHKHPGGK_00857 1.06e-311 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
PHKHPGGK_00858 2.55e-26 - - - - - - - -
PHKHPGGK_00859 1.95e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
PHKHPGGK_00860 2.54e-225 ydbI - - K - - - AI-2E family transporter
PHKHPGGK_00861 3e-118 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00862 3.26e-292 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_00863 5.76e-66 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PHKHPGGK_00864 6.8e-48 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
PHKHPGGK_00865 3.54e-53 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
PHKHPGGK_00867 5.22e-125 - - - D ko:K03496 - ko00000,ko03036,ko04812 VirC1 protein
PHKHPGGK_00868 4.18e-208 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
PHKHPGGK_00869 1.79e-74 - - - L - - - Resolvase, N-terminal
PHKHPGGK_00871 1.13e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PHKHPGGK_00872 0.000868 - - - - - - - -
PHKHPGGK_00873 2.04e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
PHKHPGGK_00874 6.6e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHKHPGGK_00875 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PHKHPGGK_00876 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
PHKHPGGK_00877 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PHKHPGGK_00878 9.9e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PHKHPGGK_00879 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
PHKHPGGK_00880 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
PHKHPGGK_00881 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHKHPGGK_00882 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
PHKHPGGK_00883 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHKHPGGK_00884 3.09e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_00885 3.41e-88 - - - - - - - -
PHKHPGGK_00886 2.52e-32 - - - - - - - -
PHKHPGGK_00887 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PHKHPGGK_00888 2.13e-63 - - - - - - - -
PHKHPGGK_00889 7.66e-32 - - - - - - - -
PHKHPGGK_00890 7.87e-30 - - - - - - - -
PHKHPGGK_00894 5.02e-180 blpT - - - - - - -
PHKHPGGK_00895 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
PHKHPGGK_00896 1.85e-141 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHKHPGGK_00897 1.45e-133 - - - - - - - -
PHKHPGGK_00899 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHKHPGGK_00900 7.72e-156 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PHKHPGGK_00901 6.07e-138 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
PHKHPGGK_00902 4.66e-179 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHKHPGGK_00903 8.63e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
PHKHPGGK_00904 8.73e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PHKHPGGK_00905 9.14e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PHKHPGGK_00906 4.84e-42 - - - - - - - -
PHKHPGGK_00907 3.11e-256 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_00908 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PHKHPGGK_00909 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PHKHPGGK_00910 1.39e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PHKHPGGK_00911 6.75e-216 - - - K - - - LysR substrate binding domain
PHKHPGGK_00912 9.32e-109 - - - S - - - PD-(D/E)XK nuclease family transposase
PHKHPGGK_00913 1.41e-51 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHKHPGGK_00914 3.01e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PHKHPGGK_00915 1.03e-206 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
PHKHPGGK_00916 2.92e-204 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHKHPGGK_00917 2.74e-06 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_00918 5.46e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHKHPGGK_00919 7.62e-134 - - - G - - - Phosphoglycerate mutase family
PHKHPGGK_00920 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
PHKHPGGK_00921 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PHKHPGGK_00922 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHKHPGGK_00923 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHKHPGGK_00924 2.34e-122 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_00925 5.74e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHKHPGGK_00926 5.31e-206 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PHKHPGGK_00927 2.57e-223 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
PHKHPGGK_00928 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
PHKHPGGK_00929 1.08e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHKHPGGK_00930 8.21e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHKHPGGK_00931 4.17e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
PHKHPGGK_00932 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
PHKHPGGK_00933 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
PHKHPGGK_00934 6.04e-49 - - - - - - - -
PHKHPGGK_00936 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
PHKHPGGK_00937 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
PHKHPGGK_00938 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
PHKHPGGK_00940 5.01e-55 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
PHKHPGGK_00941 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHKHPGGK_00942 5.38e-39 - - - - - - - -
PHKHPGGK_00943 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHKHPGGK_00944 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHKHPGGK_00945 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHKHPGGK_00946 5.58e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHKHPGGK_00947 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHKHPGGK_00948 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
PHKHPGGK_00949 1.92e-315 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHKHPGGK_00950 1.05e-240 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHKHPGGK_00951 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
PHKHPGGK_00952 5.14e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHKHPGGK_00953 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHKHPGGK_00954 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHKHPGGK_00955 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PHKHPGGK_00956 7.46e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHKHPGGK_00957 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHKHPGGK_00958 2.14e-104 - - - S - - - AAA domain
PHKHPGGK_00959 6.97e-53 - - - F - - - NUDIX domain
PHKHPGGK_00960 4.87e-187 - - - F - - - Phosphorylase superfamily
PHKHPGGK_00961 5.92e-191 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
PHKHPGGK_00962 2.25e-125 yagE - - E - - - Amino acid permease
PHKHPGGK_00963 1.11e-41 yagE - - E - - - Amino acid permease
PHKHPGGK_00964 2.75e-111 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
PHKHPGGK_00965 4.7e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHKHPGGK_00966 1.72e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHKHPGGK_00967 1.48e-142 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
PHKHPGGK_00968 8.83e-187 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
PHKHPGGK_00969 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
PHKHPGGK_00970 4.46e-89 - - - P - - - NhaP-type Na H and K H
PHKHPGGK_00971 3.21e-87 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
PHKHPGGK_00972 1.08e-95 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
PHKHPGGK_00973 2.15e-198 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHKHPGGK_00974 1e-168 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHKHPGGK_00975 1.5e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
PHKHPGGK_00976 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHKHPGGK_00977 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHKHPGGK_00978 2.09e-180 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
PHKHPGGK_00979 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PHKHPGGK_00980 1.4e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PHKHPGGK_00981 7.88e-22 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
PHKHPGGK_00983 6.88e-11 - - - T ko:K07172 - ko00000,ko02048 SpoVT / AbrB like domain
PHKHPGGK_00984 3.68e-14 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHKHPGGK_00985 3e-128 - - - M - - - Protein of unknown function (DUF3737)
PHKHPGGK_00986 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
PHKHPGGK_00987 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PHKHPGGK_00988 9.01e-90 - - - S - - - SdpI/YhfL protein family
PHKHPGGK_00989 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
PHKHPGGK_00990 0.0 yclK - - T - - - Histidine kinase
PHKHPGGK_00991 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHKHPGGK_00992 1.52e-136 vanZ - - V - - - VanZ like family
PHKHPGGK_00993 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PHKHPGGK_00994 4.63e-274 - - - EGP - - - Major Facilitator
PHKHPGGK_00995 3.94e-250 ampC - - V - - - Beta-lactamase
PHKHPGGK_00998 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
PHKHPGGK_00999 9.98e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PHKHPGGK_01000 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHKHPGGK_01001 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHKHPGGK_01002 1.36e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHKHPGGK_01003 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHKHPGGK_01004 1.01e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PHKHPGGK_01005 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHKHPGGK_01006 2.57e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHKHPGGK_01007 3.24e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHKHPGGK_01008 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHKHPGGK_01009 1.04e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHKHPGGK_01010 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHKHPGGK_01011 2.45e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PHKHPGGK_01012 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
PHKHPGGK_01013 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
PHKHPGGK_01014 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
PHKHPGGK_01015 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
PHKHPGGK_01016 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PHKHPGGK_01017 9.45e-104 uspA - - T - - - universal stress protein
PHKHPGGK_01018 1.35e-56 - - - - - - - -
PHKHPGGK_01019 5.98e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
PHKHPGGK_01020 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
PHKHPGGK_01021 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHKHPGGK_01022 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHKHPGGK_01023 1.32e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
PHKHPGGK_01024 3.48e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHKHPGGK_01025 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
PHKHPGGK_01026 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PHKHPGGK_01027 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
PHKHPGGK_01028 1.06e-86 - - - S - - - GtrA-like protein
PHKHPGGK_01029 4.08e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
PHKHPGGK_01030 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
PHKHPGGK_01031 8.53e-59 - - - - - - - -
PHKHPGGK_01032 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
PHKHPGGK_01033 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHKHPGGK_01034 3.02e-166 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
PHKHPGGK_01035 2.91e-67 - - - - - - - -
PHKHPGGK_01036 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHKHPGGK_01037 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PHKHPGGK_01038 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
PHKHPGGK_01039 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
PHKHPGGK_01040 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
PHKHPGGK_01041 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PHKHPGGK_01042 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
PHKHPGGK_01043 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
PHKHPGGK_01044 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
PHKHPGGK_01045 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PHKHPGGK_01046 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHKHPGGK_01047 6.55e-72 ftsL - - D - - - Cell division protein FtsL
PHKHPGGK_01048 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PHKHPGGK_01049 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHKHPGGK_01050 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHKHPGGK_01051 3.88e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHKHPGGK_01052 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHKHPGGK_01053 3.3e-315 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHKHPGGK_01054 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHKHPGGK_01055 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHKHPGGK_01056 2.42e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
PHKHPGGK_01057 4.01e-192 ylmH - - S - - - S4 domain protein
PHKHPGGK_01058 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
PHKHPGGK_01059 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHKHPGGK_01060 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
PHKHPGGK_01061 5.18e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PHKHPGGK_01062 1.22e-55 - - - - - - - -
PHKHPGGK_01063 2.05e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHKHPGGK_01064 1.62e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
PHKHPGGK_01065 9.98e-75 XK27_04120 - - S - - - Putative amino acid metabolism
PHKHPGGK_01066 4.47e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHKHPGGK_01067 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
PHKHPGGK_01068 2.31e-148 - - - S - - - repeat protein
PHKHPGGK_01069 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHKHPGGK_01070 0.0 - - - L - - - Nuclease-related domain
PHKHPGGK_01071 1.75e-211 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PHKHPGGK_01072 1.04e-144 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
PHKHPGGK_01073 1.3e-62 - - - L - - - DNA helicase
PHKHPGGK_01074 6.75e-101 - - - S - - - HIRAN
PHKHPGGK_01075 8.53e-45 - - - - - - - -
PHKHPGGK_01076 3.02e-232 - - - - - - - -
PHKHPGGK_01077 5.77e-127 - - - S - - - AAA domain
PHKHPGGK_01078 8.99e-100 - - - S ko:K07126 - ko00000 Sel1-like repeats.
PHKHPGGK_01079 5.56e-07 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHKHPGGK_01080 3.15e-132 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
PHKHPGGK_01081 1.61e-70 - - - - - - - -
PHKHPGGK_01082 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
PHKHPGGK_01083 1.1e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHKHPGGK_01084 2.28e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHKHPGGK_01085 2.91e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PHKHPGGK_01086 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
PHKHPGGK_01087 0.0 FbpA - - K - - - Fibronectin-binding protein
PHKHPGGK_01088 2.06e-88 - - - - - - - -
PHKHPGGK_01089 1.15e-204 - - - S - - - EDD domain protein, DegV family
PHKHPGGK_01090 4.65e-219 - - - L - - - Bifunctional protein
PHKHPGGK_01091 6.1e-186 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_01092 9.92e-65 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_01093 1.44e-234 - - - L - - - Phage integrase family
PHKHPGGK_01094 1.61e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PHKHPGGK_01095 3.22e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHKHPGGK_01096 5.08e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHKHPGGK_01097 6.51e-177 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHKHPGGK_01098 5.5e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHKHPGGK_01099 1.02e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHKHPGGK_01100 1.29e-79 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PHKHPGGK_01101 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHKHPGGK_01102 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHKHPGGK_01103 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHKHPGGK_01104 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PHKHPGGK_01105 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHKHPGGK_01106 3.7e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHKHPGGK_01107 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHKHPGGK_01108 2.86e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
PHKHPGGK_01109 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PHKHPGGK_01110 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHKHPGGK_01111 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHKHPGGK_01112 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHKHPGGK_01113 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHKHPGGK_01114 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHKHPGGK_01115 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHKHPGGK_01116 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHKHPGGK_01117 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHKHPGGK_01118 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHKHPGGK_01119 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PHKHPGGK_01120 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHKHPGGK_01121 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHKHPGGK_01122 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHKHPGGK_01123 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHKHPGGK_01124 3.3e-197 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHKHPGGK_01125 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHKHPGGK_01126 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PHKHPGGK_01127 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHKHPGGK_01128 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PHKHPGGK_01129 1.2e-220 - - - - - - - -
PHKHPGGK_01130 1.86e-31 - - - K - - - Acetyltransferase (GNAT) domain
PHKHPGGK_01132 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
PHKHPGGK_01133 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
PHKHPGGK_01134 1.89e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
PHKHPGGK_01135 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHKHPGGK_01136 1.23e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHKHPGGK_01137 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
PHKHPGGK_01138 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_01139 1.64e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
PHKHPGGK_01140 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHKHPGGK_01141 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHKHPGGK_01142 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
PHKHPGGK_01143 1.29e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
PHKHPGGK_01144 5.11e-203 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PHKHPGGK_01145 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
PHKHPGGK_01146 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
PHKHPGGK_01150 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHKHPGGK_01151 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PHKHPGGK_01152 1.21e-213 yitL - - S ko:K00243 - ko00000 S1 domain
PHKHPGGK_01153 6.74e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
PHKHPGGK_01154 1.13e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHKHPGGK_01155 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHKHPGGK_01156 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHKHPGGK_01157 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PHKHPGGK_01158 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHKHPGGK_01159 1.13e-41 - - - M - - - Lysin motif
PHKHPGGK_01160 1.96e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PHKHPGGK_01161 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PHKHPGGK_01162 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PHKHPGGK_01163 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHKHPGGK_01164 3.52e-293 XK27_05225 - - S - - - Tetratricopeptide repeat protein
PHKHPGGK_01165 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHKHPGGK_01166 0.0 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_01167 9.44e-117 yokL3 - - J - - - Acetyltransferase (GNAT) domain
PHKHPGGK_01168 2.56e-291 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHKHPGGK_01169 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHKHPGGK_01170 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PHKHPGGK_01171 2.58e-48 potE - - E - - - Amino Acid
PHKHPGGK_01172 1.27e-220 potE - - E - - - Amino Acid
PHKHPGGK_01173 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHKHPGGK_01174 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PHKHPGGK_01175 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHKHPGGK_01176 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHKHPGGK_01177 3.29e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHKHPGGK_01178 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHKHPGGK_01179 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHKHPGGK_01180 9.03e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHKHPGGK_01181 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHKHPGGK_01182 4.2e-249 pbpX1 - - V - - - Beta-lactamase
PHKHPGGK_01183 0.0 - - - I - - - Protein of unknown function (DUF2974)
PHKHPGGK_01184 5.73e-153 - - - - - - - -
PHKHPGGK_01185 2.26e-31 - - - S - - - Transglycosylase associated protein
PHKHPGGK_01186 3.81e-18 - - - S - - - CsbD-like
PHKHPGGK_01187 4.07e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
PHKHPGGK_01188 4.23e-46 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01189 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHKHPGGK_01190 5.43e-191 - - - - - - - -
PHKHPGGK_01191 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHKHPGGK_01192 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHKHPGGK_01193 3.64e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PHKHPGGK_01194 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PHKHPGGK_01195 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PHKHPGGK_01196 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
PHKHPGGK_01197 1.42e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PHKHPGGK_01198 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHKHPGGK_01199 5.21e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
PHKHPGGK_01200 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
PHKHPGGK_01201 3.91e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PHKHPGGK_01202 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PHKHPGGK_01203 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHKHPGGK_01204 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
PHKHPGGK_01205 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHKHPGGK_01206 1.29e-164 - - - S - - - SLAP domain
PHKHPGGK_01207 4.34e-64 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHKHPGGK_01208 9.13e-157 - - - L - - - PFAM transposase IS116 IS110 IS902
PHKHPGGK_01209 7.61e-42 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
PHKHPGGK_01210 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
PHKHPGGK_01211 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
PHKHPGGK_01212 2.44e-210 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
PHKHPGGK_01213 2.84e-240 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PHKHPGGK_01214 4.35e-185 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
PHKHPGGK_01215 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
PHKHPGGK_01216 1.48e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PHKHPGGK_01217 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
PHKHPGGK_01218 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
PHKHPGGK_01219 3.56e-281 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHKHPGGK_01220 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PHKHPGGK_01221 1.6e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
PHKHPGGK_01222 2.14e-48 - - - - - - - -
PHKHPGGK_01223 6.89e-93 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
PHKHPGGK_01224 0.0 XK27_08315 - - M - - - Sulfatase
PHKHPGGK_01225 1.03e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHKHPGGK_01226 2.92e-258 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHKHPGGK_01227 5.18e-128 - - - G - - - Aldose 1-epimerase
PHKHPGGK_01228 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHKHPGGK_01229 1.72e-149 - - - - - - - -
PHKHPGGK_01230 1.98e-168 - - - - - - - -
PHKHPGGK_01231 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHKHPGGK_01232 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PHKHPGGK_01233 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
PHKHPGGK_01234 1.14e-235 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
PHKHPGGK_01235 1.47e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PHKHPGGK_01237 1.3e-162 - - - S - - - SLAP domain
PHKHPGGK_01238 5.44e-44 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01239 0.0 - - - L - - - Transposase DDE domain
PHKHPGGK_01240 2.22e-296 - - - E ko:K03294 - ko00000 amino acid
PHKHPGGK_01241 6.59e-296 - - - L - - - Transposase DDE domain
PHKHPGGK_01242 5.03e-76 - - - K - - - Helix-turn-helix domain
PHKHPGGK_01243 1.17e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHKHPGGK_01244 1.05e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
PHKHPGGK_01245 1.11e-234 - - - K - - - Transcriptional regulator
PHKHPGGK_01246 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHKHPGGK_01247 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHKHPGGK_01248 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHKHPGGK_01249 0.0 snf - - KL - - - domain protein
PHKHPGGK_01250 1.73e-48 - - - - - - - -
PHKHPGGK_01251 1.24e-08 - - - - - - - -
PHKHPGGK_01252 4.83e-136 pncA - - Q - - - Isochorismatase family
PHKHPGGK_01253 1.51e-159 - - - - - - - -
PHKHPGGK_01256 4.13e-83 - - - - - - - -
PHKHPGGK_01257 3.56e-47 - - - - - - - -
PHKHPGGK_01258 5.77e-25 - - - EL - - - Toprim-like
PHKHPGGK_01259 1.19e-31 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
PHKHPGGK_01260 1.47e-18 - - - - - - - -
PHKHPGGK_01262 2.62e-155 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHKHPGGK_01264 4.97e-29 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHKHPGGK_01266 2.78e-45 - - - - - - - -
PHKHPGGK_01267 2.19e-87 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
PHKHPGGK_01269 5.85e-67 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01270 1.78e-21 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01272 7.62e-32 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_01273 8.24e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHKHPGGK_01274 4.68e-25 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHKHPGGK_01275 7.98e-35 - - - GKT - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_01276 1.71e-156 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PHKHPGGK_01277 6.73e-129 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01278 9.69e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PHKHPGGK_01279 2.56e-179 - - - S - - - haloacid dehalogenase-like hydrolase
PHKHPGGK_01280 6.64e-94 - - - - - - - -
PHKHPGGK_01281 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
PHKHPGGK_01282 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
PHKHPGGK_01283 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHKHPGGK_01284 3.08e-205 - - - S - - - Aldo/keto reductase family
PHKHPGGK_01285 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHKHPGGK_01286 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHKHPGGK_01287 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
PHKHPGGK_01288 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
PHKHPGGK_01289 1.97e-255 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
PHKHPGGK_01290 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
PHKHPGGK_01291 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PHKHPGGK_01292 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_01293 5.14e-248 - - - S - - - DUF218 domain
PHKHPGGK_01294 3.43e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHKHPGGK_01295 1.49e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
PHKHPGGK_01296 3.62e-202 - - - EGP - - - Major facilitator Superfamily
PHKHPGGK_01297 1.05e-67 - - - - - - - -
PHKHPGGK_01298 1.91e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_01299 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
PHKHPGGK_01300 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
PHKHPGGK_01301 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
PHKHPGGK_01302 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
PHKHPGGK_01303 0.0 cadA - - P - - - P-type ATPase
PHKHPGGK_01304 3.41e-107 ykuL - - S - - - (CBS) domain
PHKHPGGK_01305 5.11e-265 - - - S - - - Membrane
PHKHPGGK_01306 1.42e-58 - - - - - - - -
PHKHPGGK_01307 9.18e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
PHKHPGGK_01308 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHKHPGGK_01309 3.08e-306 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
PHKHPGGK_01310 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHKHPGGK_01311 9.71e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHKHPGGK_01312 1.97e-227 pbpX2 - - V - - - Beta-lactamase
PHKHPGGK_01313 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
PHKHPGGK_01314 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHKHPGGK_01315 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PHKHPGGK_01316 1.96e-49 - - - - - - - -
PHKHPGGK_01317 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHKHPGGK_01318 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_01319 3.09e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_01320 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHKHPGGK_01321 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
PHKHPGGK_01322 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PHKHPGGK_01323 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
PHKHPGGK_01324 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
PHKHPGGK_01325 6.36e-173 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_01326 1.95e-221 - - - V - - - HNH endonuclease
PHKHPGGK_01328 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
PHKHPGGK_01329 6.45e-291 - - - E - - - amino acid
PHKHPGGK_01330 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
PHKHPGGK_01331 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
PHKHPGGK_01334 1.35e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHKHPGGK_01335 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHKHPGGK_01336 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHKHPGGK_01337 5.93e-50 eriC - - P ko:K03281 - ko00000 chloride
PHKHPGGK_01338 6.55e-76 eriC - - P ko:K03281 - ko00000 chloride
PHKHPGGK_01339 1.45e-34 - - - K - - - FCD
PHKHPGGK_01340 3.22e-121 ydiM - - G - - - Major facilitator superfamily
PHKHPGGK_01341 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHKHPGGK_01342 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHKHPGGK_01343 1.72e-92 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHKHPGGK_01344 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
PHKHPGGK_01345 5.5e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PHKHPGGK_01346 1.8e-34 - - - - - - - -
PHKHPGGK_01347 0.0 sufI - - Q - - - Multicopper oxidase
PHKHPGGK_01348 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHKHPGGK_01349 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHKHPGGK_01350 2.77e-292 - - - Q - - - Imidazolonepropionase and related amidohydrolases
PHKHPGGK_01351 5.84e-312 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
PHKHPGGK_01352 1.3e-175 - - - S - - - Protein of unknown function (DUF3100)
PHKHPGGK_01353 2.04e-60 - - - S - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01354 7.7e-126 - - - L - - - Helix-turn-helix domain
PHKHPGGK_01355 1.89e-23 - - - - - - - -
PHKHPGGK_01356 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
PHKHPGGK_01357 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
PHKHPGGK_01358 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
PHKHPGGK_01359 4.48e-34 - - - - - - - -
PHKHPGGK_01360 1.07e-35 - - - - - - - -
PHKHPGGK_01361 1.95e-45 - - - - - - - -
PHKHPGGK_01362 6.94e-70 - - - S - - - Enterocin A Immunity
PHKHPGGK_01363 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PHKHPGGK_01364 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHKHPGGK_01365 9.28e-271 - - - T - - - His Kinase A (phosphoacceptor) domain
PHKHPGGK_01366 8.32e-157 vanR - - K - - - response regulator
PHKHPGGK_01368 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
PHKHPGGK_01369 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_01370 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_01371 1.08e-229 - - - L - - - DDE superfamily endonuclease
PHKHPGGK_01372 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHKHPGGK_01373 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
PHKHPGGK_01374 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
PHKHPGGK_01375 7.44e-192 yycI - - S - - - YycH protein
PHKHPGGK_01376 0.0 yycH - - S - - - YycH protein
PHKHPGGK_01377 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHKHPGGK_01378 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PHKHPGGK_01380 1.09e-46 - - - - - - - -
PHKHPGGK_01382 4.19e-192 - - - I - - - Acyl-transferase
PHKHPGGK_01383 7.23e-201 arbx - - M - - - Glycosyl transferase family 8
PHKHPGGK_01384 1.91e-236 - - - M - - - Glycosyl transferase family 8
PHKHPGGK_01385 5.48e-235 - - - M - - - Glycosyl transferase family 8
PHKHPGGK_01386 3.92e-215 arbZ - - I - - - Phosphate acyltransferases
PHKHPGGK_01387 3.37e-50 - - - S - - - Cytochrome B5
PHKHPGGK_01388 1.38e-107 - - - J - - - FR47-like protein
PHKHPGGK_01389 3.11e-13 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PHKHPGGK_01391 1e-156 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
PHKHPGGK_01392 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
PHKHPGGK_01393 3.68e-276 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
PHKHPGGK_01394 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
PHKHPGGK_01395 0.0 - - - S - - - SLAP domain
PHKHPGGK_01397 2.52e-303 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
PHKHPGGK_01398 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
PHKHPGGK_01399 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHKHPGGK_01400 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
PHKHPGGK_01401 2.82e-97 - - - S - - - Glycosyltransferase family 28 C-terminal domain
PHKHPGGK_01402 2.38e-130 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHKHPGGK_01403 2.56e-66 - - - M - - - Domain of unknown function (DUF1919)
PHKHPGGK_01404 5.18e-109 - - - M - - - Glycosyltransferase like family 2
PHKHPGGK_01405 2.94e-94 - - - S - - - Bacterial transferase hexapeptide (six repeats)
PHKHPGGK_01407 3.38e-91 - - - M - - - Glycosyltransferase like family 2
PHKHPGGK_01408 1.94e-188 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
PHKHPGGK_01409 2.39e-85 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PHKHPGGK_01410 3.05e-53 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_01411 3.94e-254 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHKHPGGK_01412 1.38e-46 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHKHPGGK_01413 8.46e-98 - - - S - - - Uncharacterised protein family UPF0047
PHKHPGGK_01414 1.55e-82 - - - M - - - SIS domain
PHKHPGGK_01415 3.53e-63 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PHKHPGGK_01416 5.28e-215 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PHKHPGGK_01417 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHKHPGGK_01418 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHKHPGGK_01419 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHKHPGGK_01420 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
PHKHPGGK_01421 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHKHPGGK_01422 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHKHPGGK_01423 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHKHPGGK_01424 1.11e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
PHKHPGGK_01425 3.11e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_01426 1.1e-128 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_01427 6.18e-123 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
PHKHPGGK_01428 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHKHPGGK_01429 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PHKHPGGK_01430 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHKHPGGK_01431 1.25e-192 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PHKHPGGK_01432 2.47e-254 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
PHKHPGGK_01433 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
PHKHPGGK_01434 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
PHKHPGGK_01435 1.02e-156 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHKHPGGK_01436 9.22e-141 yqeK - - H - - - Hydrolase, HD family
PHKHPGGK_01437 5.09e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHKHPGGK_01438 4.63e-275 ylbM - - S - - - Belongs to the UPF0348 family
PHKHPGGK_01439 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
PHKHPGGK_01440 3.52e-163 csrR - - K - - - response regulator
PHKHPGGK_01441 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHKHPGGK_01442 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PHKHPGGK_01443 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
PHKHPGGK_01444 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PHKHPGGK_01445 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PHKHPGGK_01446 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
PHKHPGGK_01447 1.18e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PHKHPGGK_01448 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHKHPGGK_01449 0.0 oatA - - I - - - Acyltransferase
PHKHPGGK_01450 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHKHPGGK_01451 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHKHPGGK_01452 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
PHKHPGGK_01453 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHKHPGGK_01454 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHKHPGGK_01455 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
PHKHPGGK_01456 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHKHPGGK_01457 5.35e-224 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHKHPGGK_01458 1.75e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
PHKHPGGK_01459 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
PHKHPGGK_01487 4.63e-32 - - - - - - - -
PHKHPGGK_01488 6.72e-177 - - - EP - - - Plasmid replication protein
PHKHPGGK_01489 6.76e-101 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
PHKHPGGK_01490 2.58e-220 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
PHKHPGGK_01491 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_01492 1.97e-294 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHKHPGGK_01493 1.13e-40 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHKHPGGK_01494 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
PHKHPGGK_01495 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
PHKHPGGK_01496 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PHKHPGGK_01497 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
PHKHPGGK_01498 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
PHKHPGGK_01499 1.01e-22 - - - L - - - Transposase
PHKHPGGK_01500 7.51e-16 - - - L - - - Transposase
PHKHPGGK_01501 1.21e-72 - - - K - - - Acetyltransferase (GNAT) domain
PHKHPGGK_01503 4.4e-86 - - - K - - - LytTr DNA-binding domain
PHKHPGGK_01504 6.11e-66 - - - S - - - Protein of unknown function (DUF3021)
PHKHPGGK_01505 2.64e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
PHKHPGGK_01506 2.7e-153 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHKHPGGK_01507 7.36e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
PHKHPGGK_01508 1.34e-161 - - - G - - - Belongs to the phosphoglycerate mutase family
PHKHPGGK_01509 5.08e-207 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
PHKHPGGK_01510 2.42e-33 - - - - - - - -
PHKHPGGK_01511 9.82e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHKHPGGK_01512 2.32e-234 - - - S - - - AAA domain
PHKHPGGK_01513 2.13e-66 - - - - - - - -
PHKHPGGK_01514 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
PHKHPGGK_01515 4.51e-69 - - - - - - - -
PHKHPGGK_01516 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
PHKHPGGK_01517 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHKHPGGK_01518 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHKHPGGK_01519 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHKHPGGK_01520 2.45e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHKHPGGK_01521 2.69e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHKHPGGK_01522 1.55e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PHKHPGGK_01523 1.19e-45 - - - - - - - -
PHKHPGGK_01524 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PHKHPGGK_01525 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHKHPGGK_01526 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHKHPGGK_01527 5e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PHKHPGGK_01528 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHKHPGGK_01529 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHKHPGGK_01530 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PHKHPGGK_01531 1.13e-210 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PHKHPGGK_01532 2.48e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
PHKHPGGK_01533 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHKHPGGK_01534 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHKHPGGK_01535 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
PHKHPGGK_01536 1.61e-117 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_01538 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHKHPGGK_01539 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHKHPGGK_01540 3.64e-188 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
PHKHPGGK_01541 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PHKHPGGK_01542 6.15e-36 - - - - - - - -
PHKHPGGK_01543 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHKHPGGK_01544 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHKHPGGK_01545 5.57e-107 - - - M - - - family 8
PHKHPGGK_01546 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHKHPGGK_01547 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHKHPGGK_01548 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
PHKHPGGK_01549 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHKHPGGK_01550 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
PHKHPGGK_01551 8.4e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PHKHPGGK_01552 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
PHKHPGGK_01553 3.05e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHKHPGGK_01554 4.27e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
PHKHPGGK_01555 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
PHKHPGGK_01556 3.27e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
PHKHPGGK_01557 3.93e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
PHKHPGGK_01558 1.31e-245 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHKHPGGK_01559 5.6e-133 - - - L ko:K07484 - ko00000 Transposase IS66 family
PHKHPGGK_01560 2.24e-162 - - - L - - - Transposase and inactivated derivatives
PHKHPGGK_01561 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
PHKHPGGK_01562 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
PHKHPGGK_01563 9.48e-31 - - - - - - - -
PHKHPGGK_01564 3.06e-53 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PHKHPGGK_01565 6.43e-230 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PHKHPGGK_01566 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PHKHPGGK_01567 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
PHKHPGGK_01568 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHKHPGGK_01569 5.61e-38 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PHKHPGGK_01570 3.17e-189 - - - S - - - Putative ABC-transporter type IV
PHKHPGGK_01572 4.11e-124 potE - - E - - - thought to be involved in transport amino acids across the membrane
PHKHPGGK_01574 2.67e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PHKHPGGK_01575 6.66e-27 - - - S - - - CAAX protease self-immunity
PHKHPGGK_01577 1.25e-94 - - - K - - - Helix-turn-helix domain
PHKHPGGK_01578 4.82e-144 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_01581 2.41e-39 - - - - - - - -
PHKHPGGK_01582 5.67e-278 yqjV - - EGP - - - Major Facilitator Superfamily
PHKHPGGK_01583 1.27e-58 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
PHKHPGGK_01584 1.36e-211 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
PHKHPGGK_01585 7.62e-223 - - - - - - - -
PHKHPGGK_01586 2.2e-79 lysM - - M - - - LysM domain
PHKHPGGK_01587 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
PHKHPGGK_01588 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
PHKHPGGK_01589 6.93e-34 - - - S - - - Sugar efflux transporter for intercellular exchange
PHKHPGGK_01590 5.3e-92 - - - K - - - LytTr DNA-binding domain
PHKHPGGK_01591 3.15e-121 - - - S - - - membrane
PHKHPGGK_01592 2.61e-23 - - - - - - - -
PHKHPGGK_01593 3.58e-251 - - - S - - - Putative peptidoglycan binding domain
PHKHPGGK_01594 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
PHKHPGGK_01595 5.5e-155 - - - - - - - -
PHKHPGGK_01596 2.15e-127 - - - L - - - Helix-turn-helix domain
PHKHPGGK_01597 1.14e-164 - - - S - - - Fic/DOC family
PHKHPGGK_01598 5.88e-212 repA - - S - - - Replication initiator protein A
PHKHPGGK_01599 4.65e-184 - - - D - - - AAA domain
PHKHPGGK_01600 1.17e-38 - - - - - - - -
PHKHPGGK_01601 4.87e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PHKHPGGK_01602 6.91e-92 - - - L - - - IS1381, transposase OrfA
PHKHPGGK_01603 1.07e-141 tnpR1 - - L - - - Resolvase, N terminal domain
PHKHPGGK_01604 1.48e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHKHPGGK_01605 5.23e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
PHKHPGGK_01606 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHKHPGGK_01607 4.26e-22 - - - L ko:K07467 - ko00000 Replication initiation factor
PHKHPGGK_01608 2.43e-95 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PHKHPGGK_01609 2.33e-130 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
PHKHPGGK_01610 3.87e-15 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
PHKHPGGK_01611 1.63e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PHKHPGGK_01612 1.73e-227 - - - S - - - Conserved hypothetical protein 698
PHKHPGGK_01614 1.21e-243 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHKHPGGK_01615 2.75e-130 - - - I - - - PAP2 superfamily
PHKHPGGK_01616 1.23e-187 - - - S - - - Uncharacterised protein, DegV family COG1307
PHKHPGGK_01617 1.43e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHKHPGGK_01618 8.85e-94 - - - S - - - Domain of unknown function (DUF4767)
PHKHPGGK_01619 2.08e-95 yfhC - - C - - - nitroreductase
PHKHPGGK_01620 6.36e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
PHKHPGGK_01621 4.24e-46 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHKHPGGK_01622 8.41e-42 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PHKHPGGK_01623 5.95e-72 ykoJ - - S - - - Peptidase propeptide and YPEB domain
PHKHPGGK_01624 5.32e-285 - - - I - - - Protein of unknown function (DUF2974)
PHKHPGGK_01625 7.74e-61 - - - - - - - -
PHKHPGGK_01626 1.04e-48 ybcH - - D ko:K06889 - ko00000 Alpha beta
PHKHPGGK_01627 1.94e-150 ybcH - - D ko:K06889 - ko00000 Alpha beta
PHKHPGGK_01628 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHKHPGGK_01629 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
PHKHPGGK_01630 1.74e-111 - - - - - - - -
PHKHPGGK_01631 7.76e-98 - - - - - - - -
PHKHPGGK_01632 1.76e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
PHKHPGGK_01633 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHKHPGGK_01634 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
PHKHPGGK_01635 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
PHKHPGGK_01636 3.65e-84 - - - L - - - PFAM transposase IS116 IS110 IS902
PHKHPGGK_01637 1.29e-27 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
PHKHPGGK_01638 3.75e-168 - - - K - - - rpiR family
PHKHPGGK_01639 7.66e-248 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
PHKHPGGK_01640 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHKHPGGK_01641 1.32e-151 - - - S - - - Putative esterase
PHKHPGGK_01642 3.39e-154 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PHKHPGGK_01643 1.92e-102 - - - K - - - Helix-turn-helix domain, rpiR family
PHKHPGGK_01645 0.0 mdr - - EGP - - - Major Facilitator
PHKHPGGK_01646 7.29e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHKHPGGK_01649 5.31e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PHKHPGGK_01652 4.56e-24 - - - L - - - transposase and inactivated derivatives, IS30 family
PHKHPGGK_01653 1.06e-210 - - - L - - - Transposase and inactivated derivatives, IS30 family
PHKHPGGK_01654 2.1e-31 - - - - - - - -
PHKHPGGK_01655 1.69e-06 - - - - - - - -
PHKHPGGK_01656 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHKHPGGK_01657 4.69e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHKHPGGK_01658 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PHKHPGGK_01659 2.8e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHKHPGGK_01660 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_01661 2.46e-302 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_01662 6.09e-233 - - - S - - - Uncharacterised protein family (UPF0236)
PHKHPGGK_01663 7.15e-300 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
PHKHPGGK_01664 1.59e-61 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PHKHPGGK_01666 9.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PHKHPGGK_01667 2.23e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHKHPGGK_01668 5.6e-129 - - - M - - - ErfK YbiS YcfS YnhG
PHKHPGGK_01669 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PHKHPGGK_01670 6.03e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
PHKHPGGK_01671 8.08e-108 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_01672 9.96e-45 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_01673 2.13e-42 - - - S - - - PFAM Archaeal ATPase
PHKHPGGK_01674 7.02e-36 - - - - - - - -
PHKHPGGK_01675 1.01e-98 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
PHKHPGGK_01676 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
PHKHPGGK_01677 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHKHPGGK_01678 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
PHKHPGGK_01679 2.48e-196 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PHKHPGGK_01680 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
PHKHPGGK_01681 1.18e-190 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PHKHPGGK_01682 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
PHKHPGGK_01683 2.99e-75 cvpA - - S - - - Colicin V production protein
PHKHPGGK_01684 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHKHPGGK_01685 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHKHPGGK_01686 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PHKHPGGK_01687 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PHKHPGGK_01688 1.25e-143 - - - K - - - WHG domain
PHKHPGGK_01689 2.63e-50 - - - - - - - -
PHKHPGGK_01690 2.14e-103 - - - - - - - -
PHKHPGGK_01691 4.97e-64 - - - S - - - Metal binding domain of Ada
PHKHPGGK_01692 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
PHKHPGGK_01693 3.03e-177 lysR5 - - K - - - LysR substrate binding domain
PHKHPGGK_01694 2.4e-297 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
PHKHPGGK_01695 5.39e-84 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHKHPGGK_01696 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
PHKHPGGK_01697 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PHKHPGGK_01698 1.07e-287 - - - S - - - Sterol carrier protein domain
PHKHPGGK_01699 4.04e-29 - - - - - - - -
PHKHPGGK_01700 6.93e-140 - - - K - - - LysR substrate binding domain
PHKHPGGK_01701 1.13e-126 - - - - - - - -
PHKHPGGK_01702 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
PHKHPGGK_01703 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
PHKHPGGK_01705 1.04e-41 - - - - - - - -
PHKHPGGK_01706 2.77e-220 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
PHKHPGGK_01707 1.25e-17 - - - - - - - -
PHKHPGGK_01708 1.83e-22 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_01709 6.31e-99 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_01710 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_01711 1.33e-130 - - - M - - - LysM domain protein
PHKHPGGK_01712 5.68e-211 - - - D - - - nuclear chromosome segregation
PHKHPGGK_01713 8.92e-136 - - - G - - - Phosphoglycerate mutase family
PHKHPGGK_01714 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
PHKHPGGK_01715 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
PHKHPGGK_01716 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PHKHPGGK_01718 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
PHKHPGGK_01720 1.93e-266 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHKHPGGK_01721 1.03e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHKHPGGK_01722 3.01e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PHKHPGGK_01723 1.43e-186 - - - K - - - SIS domain
PHKHPGGK_01724 9.6e-309 slpX - - S - - - SLAP domain
PHKHPGGK_01725 5.24e-31 - - - S - - - transposase or invertase
PHKHPGGK_01726 1.48e-14 - - - - - - - -
PHKHPGGK_01727 7.62e-306 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
PHKHPGGK_01730 1.01e-302 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_01731 1.15e-54 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_01732 2.17e-232 - - - - - - - -
PHKHPGGK_01733 9.75e-163 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
PHKHPGGK_01734 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
PHKHPGGK_01735 3.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PHKHPGGK_01736 1.03e-261 - - - M - - - Glycosyl transferases group 1
PHKHPGGK_01737 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHKHPGGK_01738 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHKHPGGK_01739 9.83e-261 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
PHKHPGGK_01740 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHKHPGGK_01741 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHKHPGGK_01742 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PHKHPGGK_01743 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
PHKHPGGK_01744 2.62e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PHKHPGGK_01746 2.26e-118 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
PHKHPGGK_01747 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PHKHPGGK_01748 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHKHPGGK_01749 6.25e-268 camS - - S - - - sex pheromone
PHKHPGGK_01750 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHKHPGGK_01751 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHKHPGGK_01752 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHKHPGGK_01753 5.58e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
PHKHPGGK_01754 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
PHKHPGGK_01755 1.46e-75 - - - - - - - -
PHKHPGGK_01756 9.92e-187 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
PHKHPGGK_01757 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
PHKHPGGK_01758 1.01e-256 flp - - V - - - Beta-lactamase
PHKHPGGK_01759 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHKHPGGK_01760 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
PHKHPGGK_01765 0.0 qacA - - EGP - - - Major Facilitator
PHKHPGGK_01766 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
PHKHPGGK_01767 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
PHKHPGGK_01768 6.61e-186 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_01769 7.23e-50 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PHKHPGGK_01770 0.0 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_01771 2.27e-179 - - - - - - - -
PHKHPGGK_01775 2.23e-48 - - - - - - - -
PHKHPGGK_01776 2.52e-76 - - - S - - - Cupredoxin-like domain
PHKHPGGK_01777 4.44e-65 - - - S - - - Cupredoxin-like domain
PHKHPGGK_01778 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PHKHPGGK_01779 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
PHKHPGGK_01780 7.41e-136 - - - - - - - -
PHKHPGGK_01781 1.03e-65 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
PHKHPGGK_01784 1.86e-114 ymdB - - S - - - Macro domain protein
PHKHPGGK_01785 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
PHKHPGGK_01786 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PHKHPGGK_01787 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
PHKHPGGK_01788 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PHKHPGGK_01789 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHKHPGGK_01790 5.47e-151 - - - - - - - -
PHKHPGGK_01791 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHKHPGGK_01793 1.22e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHKHPGGK_01794 2e-149 - - - S - - - Peptidase family M23
PHKHPGGK_01795 5.26e-15 - - - - - - - -
PHKHPGGK_01797 9.28e-317 - - - S - - - Putative threonine/serine exporter
PHKHPGGK_01798 1.05e-226 citR - - K - - - Putative sugar-binding domain
PHKHPGGK_01799 2.41e-66 - - - - - - - -
PHKHPGGK_01800 7.91e-14 - - - - - - - -
PHKHPGGK_01801 8.1e-87 - - - S - - - Domain of unknown function DUF1828
PHKHPGGK_01802 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
PHKHPGGK_01803 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_01804 2.58e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
PHKHPGGK_01805 1.2e-30 - - - - - - - -
PHKHPGGK_01806 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
PHKHPGGK_01808 7.88e-59 - - - L - - - Transposase, IS116 IS110 IS902 family
PHKHPGGK_01809 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
PHKHPGGK_01810 8.13e-169 - - - G ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PHKHPGGK_01811 0.0 - 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
PHKHPGGK_01812 4.34e-198 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, fructose-specific IIC component
PHKHPGGK_01813 5.84e-50 - - - G - - - Psort location Cytoplasmic, score 9.98
PHKHPGGK_01814 2.4e-54 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHKHPGGK_01815 5.51e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHKHPGGK_01816 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHKHPGGK_01817 7.1e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PHKHPGGK_01818 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHKHPGGK_01819 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHKHPGGK_01820 3.8e-80 - - - - - - - -
PHKHPGGK_01821 4.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
PHKHPGGK_01822 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHKHPGGK_01823 3.06e-68 - - - L - - - Transposase and inactivated derivatives
PHKHPGGK_01825 3.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHKHPGGK_01826 3.9e-130 ylbE - - GM - - - NAD(P)H-binding
PHKHPGGK_01827 2.33e-120 - - - S - - - VanZ like family
PHKHPGGK_01828 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
PHKHPGGK_01829 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
PHKHPGGK_01830 1.72e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
PHKHPGGK_01831 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
PHKHPGGK_01832 8.19e-91 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
PHKHPGGK_01833 1.68e-55 - - - - - - - -
PHKHPGGK_01834 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PHKHPGGK_01835 3.69e-30 - - - - - - - -
PHKHPGGK_01836 2.42e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
PHKHPGGK_01837 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHKHPGGK_01839 4.38e-150 - - - S ko:K07507 - ko00000,ko02000 MgtC family
PHKHPGGK_01842 7.2e-84 - - - - - - - -
PHKHPGGK_01843 7.06e-110 - - - - - - - -
PHKHPGGK_01844 1.36e-171 - - - D - - - Ftsk spoiiie family protein
PHKHPGGK_01845 5.28e-180 - - - S - - - Replication initiation factor
PHKHPGGK_01846 1.33e-72 - - - - - - - -
PHKHPGGK_01847 4.04e-36 - - - - - - - -
PHKHPGGK_01848 3.5e-280 - - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_01850 9.75e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PHKHPGGK_01851 8.25e-65 - - - V ko:K01990,ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
PHKHPGGK_01853 6.56e-86 sagB - - C - - - Nitroreductase family
PHKHPGGK_01854 4e-31 dltr - - K - - - response regulator
PHKHPGGK_01855 3e-290 sptS - - T - - - Histidine kinase
PHKHPGGK_01856 1.36e-266 - - - EGP - - - Major Facilitator Superfamily
PHKHPGGK_01857 2.65e-89 - - - O - - - OsmC-like protein
PHKHPGGK_01858 1.92e-113 yhaH - - S - - - Protein of unknown function (DUF805)
PHKHPGGK_01859 5.87e-110 - - - - - - - -
PHKHPGGK_01860 0.0 - - - - - - - -
PHKHPGGK_01861 2.65e-107 - - - S - - - Fic/DOC family
PHKHPGGK_01862 0.0 potE - - E - - - Amino Acid
PHKHPGGK_01863 2.44e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHKHPGGK_01864 7.55e-53 - - - S - - - Transglycosylase associated protein
PHKHPGGK_01865 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
PHKHPGGK_01866 1.47e-158 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
PHKHPGGK_01867 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PHKHPGGK_01868 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
PHKHPGGK_01869 6.89e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
PHKHPGGK_01870 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_01871 1.36e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
PHKHPGGK_01872 1.88e-125 - - - E - - - GDSL-like Lipase/Acylhydrolase
PHKHPGGK_01873 1.95e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PHKHPGGK_01874 1.48e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHKHPGGK_01875 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
PHKHPGGK_01876 0.0 - - - S - - - Fibronectin type III domain
PHKHPGGK_01877 4.06e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHKHPGGK_01878 9.39e-71 - - - - - - - -
PHKHPGGK_01880 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
PHKHPGGK_01881 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHKHPGGK_01882 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_01883 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHKHPGGK_01884 4.39e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHKHPGGK_01885 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHKHPGGK_01886 1.11e-239 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHKHPGGK_01887 6.08e-253 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHKHPGGK_01888 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHKHPGGK_01889 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
PHKHPGGK_01890 6.87e-93 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PHKHPGGK_01891 5.69e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHKHPGGK_01892 1.43e-144 - - - - - - - -
PHKHPGGK_01894 1.66e-143 - - - E - - - Belongs to the SOS response-associated peptidase family
PHKHPGGK_01895 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHKHPGGK_01896 4.29e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
PHKHPGGK_01897 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
PHKHPGGK_01898 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
PHKHPGGK_01899 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHKHPGGK_01900 1.11e-188 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
PHKHPGGK_01901 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHKHPGGK_01902 2.14e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHKHPGGK_01903 1.42e-52 veg - - S - - - Biofilm formation stimulator VEG
PHKHPGGK_01904 9.72e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PHKHPGGK_01905 5.17e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHKHPGGK_01906 5.52e-113 - - - - - - - -
PHKHPGGK_01907 0.0 - - - S - - - SLAP domain
PHKHPGGK_01908 5.4e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHKHPGGK_01909 1.37e-219 - - - GK - - - ROK family
PHKHPGGK_01910 2.53e-56 - - - - - - - -
PHKHPGGK_01911 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHKHPGGK_01912 1.75e-89 - - - S - - - Domain of unknown function (DUF1934)
PHKHPGGK_01913 2.38e-88 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHKHPGGK_01914 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHKHPGGK_01915 1.89e-312 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHKHPGGK_01916 7.28e-97 - - - K - - - acetyltransferase
PHKHPGGK_01917 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHKHPGGK_01918 2.73e-201 msmR - - K - - - AraC-like ligand binding domain
PHKHPGGK_01919 1.08e-289 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
PHKHPGGK_01920 7.92e-135 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHKHPGGK_01921 1.1e-54 - - - K - - - Helix-turn-helix
PHKHPGGK_01922 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PHKHPGGK_01923 7.01e-207 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
PHKHPGGK_01924 4.61e-304 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
PHKHPGGK_01925 2.13e-53 - - - - - - - -
PHKHPGGK_01927 5.2e-119 - - - D - - - ftsk spoiiie
PHKHPGGK_01929 5.45e-72 - - - - - - - -
PHKHPGGK_01930 5.22e-18 - - - S - - - Domain of unknown function (DUF3173)
PHKHPGGK_01931 5.6e-11 - - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_01932 3.12e-65 - - - - - - - -
PHKHPGGK_01933 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
PHKHPGGK_01934 8.28e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PHKHPGGK_01935 7.81e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
PHKHPGGK_01936 4.65e-14 - - - - - - - -
PHKHPGGK_01937 1.42e-57 - - - - - - - -
PHKHPGGK_01938 6.28e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PHKHPGGK_01939 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHKHPGGK_01940 1.34e-162 - - - - - - - -
PHKHPGGK_01941 1.08e-307 - - - S - - - response to antibiotic
PHKHPGGK_01942 1.76e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PHKHPGGK_01943 3.99e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
PHKHPGGK_01944 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
PHKHPGGK_01945 6.38e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHKHPGGK_01946 4.25e-119 yutD - - S - - - Protein of unknown function (DUF1027)
PHKHPGGK_01947 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PHKHPGGK_01948 9.89e-74 - - - - - - - -
PHKHPGGK_01949 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PHKHPGGK_01950 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PHKHPGGK_01951 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
PHKHPGGK_01952 5.57e-22 - - - S - - - Protein of unknown function (DUF1275)
PHKHPGGK_01953 4.52e-114 - - - S - - - Protein of unknown function (DUF1275)
PHKHPGGK_01954 2.71e-222 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
PHKHPGGK_01955 6.46e-27 - - - - - - - -
PHKHPGGK_01956 1.59e-268 - - - - - - - -
PHKHPGGK_01957 6.57e-175 - - - S - - - SLAP domain
PHKHPGGK_01958 1.14e-154 - - - S - - - SLAP domain
PHKHPGGK_01959 1.06e-133 - - - S - - - Bacteriocin helveticin-J
PHKHPGGK_01960 2.35e-58 - - - - - - - -
PHKHPGGK_01961 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_01962 1.98e-41 - - - E - - - Zn peptidase
PHKHPGGK_01963 0.0 eriC - - P ko:K03281 - ko00000 chloride
PHKHPGGK_01964 7.14e-139 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
PHKHPGGK_01965 2.36e-12 - - - S - - - Bacteriophage abortive infection AbiH
PHKHPGGK_01966 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
PHKHPGGK_01970 2.45e-201 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHKHPGGK_01971 1.91e-233 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PHKHPGGK_01972 8.77e-189 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
PHKHPGGK_01973 1.13e-201 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
PHKHPGGK_01974 2.91e-83 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
PHKHPGGK_01975 8.64e-85 yybA - - K - - - Transcriptional regulator
PHKHPGGK_01976 8e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PHKHPGGK_01977 5.59e-109 - - - S - - - Peptidase propeptide and YPEB domain
PHKHPGGK_01978 2.88e-98 ykoJ - - S - - - Peptidase propeptide and YPEB domain
PHKHPGGK_01979 2.37e-242 - - - T - - - GHKL domain
PHKHPGGK_01980 1.75e-168 - - - T - - - Transcriptional regulatory protein, C terminal
PHKHPGGK_01981 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
PHKHPGGK_01982 0.0 - - - V - - - ABC transporter transmembrane region
PHKHPGGK_01983 9.75e-20 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_01984 1.15e-201 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
PHKHPGGK_01985 2.52e-194 - - - I - - - alpha/beta hydrolase fold
PHKHPGGK_01986 3.2e-143 - - - S - - - SNARE associated Golgi protein
PHKHPGGK_01987 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHKHPGGK_01988 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHKHPGGK_01989 4.98e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHKHPGGK_01990 1.44e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHKHPGGK_01991 9.06e-184 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHKHPGGK_01992 1.38e-165 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHKHPGGK_01995 5.53e-173 - - - S - - - TerB-C domain
PHKHPGGK_01996 2.14e-312 - - - P - - - P-loop Domain of unknown function (DUF2791)
PHKHPGGK_01997 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
PHKHPGGK_01998 7.82e-80 - - - - - - - -
PHKHPGGK_01999 1.49e-290 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
PHKHPGGK_02000 6.58e-175 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
PHKHPGGK_02002 3.31e-79 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
PHKHPGGK_02003 1.08e-145 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHKHPGGK_02004 1.27e-311 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PHKHPGGK_02005 8.12e-60 yitW - - S - - - Iron-sulfur cluster assembly protein
PHKHPGGK_02006 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
PHKHPGGK_02007 6.98e-78 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
PHKHPGGK_02008 1.39e-224 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHKHPGGK_02009 6.22e-232 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
PHKHPGGK_02010 4.43e-179 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
PHKHPGGK_02011 5.32e-35 - - - C ko:K21832 - ko00000 nitric oxide dioxygenase activity
PHKHPGGK_02012 7.46e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
PHKHPGGK_02013 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
PHKHPGGK_02014 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
PHKHPGGK_02015 1.4e-208 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PHKHPGGK_02016 3.22e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PHKHPGGK_02017 1.22e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PHKHPGGK_02018 4.42e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
PHKHPGGK_02022 1.44e-80 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PHKHPGGK_02023 2.1e-270 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
PHKHPGGK_02024 9.35e-63 - - - - - - - -
PHKHPGGK_02025 3.77e-86 - - - K - - - HxlR family
PHKHPGGK_02026 0.0 - - - L - - - Plasmid pRiA4b ORF-3-like protein
PHKHPGGK_02027 1.28e-310 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PHKHPGGK_02028 1.07e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
PHKHPGGK_02029 0.0 - - - M - - - Rib/alpha-like repeat
PHKHPGGK_02030 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
PHKHPGGK_02031 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PHKHPGGK_02032 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
PHKHPGGK_02033 7.7e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
PHKHPGGK_02034 5.75e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHKHPGGK_02035 2.73e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHKHPGGK_02036 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHKHPGGK_02037 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHKHPGGK_02038 4.73e-84 - - - K - - - Helix-turn-helix XRE-family like proteins
PHKHPGGK_02042 1.21e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHKHPGGK_02043 5.59e-98 - - - - - - - -
PHKHPGGK_02044 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHKHPGGK_02045 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PHKHPGGK_02046 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
PHKHPGGK_02047 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHKHPGGK_02048 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHKHPGGK_02049 7.81e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHKHPGGK_02050 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHKHPGGK_02051 1.98e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
PHKHPGGK_02052 2.53e-139 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
PHKHPGGK_02053 1.33e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
PHKHPGGK_02054 2.43e-239 - - - S - - - Bacteriocin helveticin-J
PHKHPGGK_02055 0.0 - - - M - - - Peptidase family M1 domain
PHKHPGGK_02056 2.04e-226 - - - S - - - SLAP domain
PHKHPGGK_02057 4.65e-278 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
PHKHPGGK_02058 2.59e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PHKHPGGK_02059 8.78e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHKHPGGK_02060 1.35e-71 ytpP - - CO - - - Thioredoxin
PHKHPGGK_02062 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHKHPGGK_02063 1.63e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PHKHPGGK_02064 3.67e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_02065 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
PHKHPGGK_02066 1.2e-41 - - - - - - - -
PHKHPGGK_02067 3.12e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHKHPGGK_02068 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
PHKHPGGK_02069 0.0 - - - - - - - -
PHKHPGGK_02070 9.67e-33 - - - S - - - Domain of unknown function DUF1829
PHKHPGGK_02072 4.53e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHKHPGGK_02073 0.0 yhaN - - L - - - AAA domain
PHKHPGGK_02074 4.24e-289 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
PHKHPGGK_02075 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
PHKHPGGK_02076 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PHKHPGGK_02077 1.21e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PHKHPGGK_02079 5.94e-100 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
PHKHPGGK_02080 2.25e-57 - - - K - - - Tetracycline repressor, C-terminal all-alpha domain
PHKHPGGK_02082 3.49e-113 - - - K - - - LysR substrate binding domain
PHKHPGGK_02083 1.59e-44 - - - S - - - Domain of unknown function (DUF4440)
PHKHPGGK_02084 8.27e-88 - - - GM - - - NAD(P)H-binding
PHKHPGGK_02085 1.64e-169 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PHKHPGGK_02086 1.44e-62 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHKHPGGK_02087 8.26e-123 - - - L - - - Transposase and inactivated derivatives, IS30 family
PHKHPGGK_02088 5.74e-69 - - - - - - - -
PHKHPGGK_02089 7.51e-174 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHKHPGGK_02090 1.14e-143 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
PHKHPGGK_02091 0.0 - - - G - - - PTS system sorbose-specific iic component
PHKHPGGK_02092 3.59e-69 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PHKHPGGK_02093 5.36e-100 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
PHKHPGGK_02095 1.21e-40 - - - - - - - -
PHKHPGGK_02096 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
PHKHPGGK_02097 4.54e-135 - - - S - - - SLAP domain
PHKHPGGK_02098 6.87e-27 - - - S - - - PD-(D/E)XK nuclease family transposase
PHKHPGGK_02099 5.32e-190 - - - S - - - PD-(D/E)XK nuclease family transposase
PHKHPGGK_02101 8.49e-100 - - - K - - - DNA-templated transcription, initiation
PHKHPGGK_02102 2.85e-54 - - - - - - - -
PHKHPGGK_02103 2.5e-136 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
PHKHPGGK_02104 8.45e-102 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
PHKHPGGK_02105 4.12e-205 pct 2.8.3.1 - I ko:K01026 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 ko00000,ko00001,ko01000 Coenzyme A transferase
PHKHPGGK_02106 5.38e-184 - - - K - - - LysR substrate binding domain
PHKHPGGK_02107 1.47e-70 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHKHPGGK_02108 1.41e-97 - - - S - - - ECF transporter, substrate-specific component
PHKHPGGK_02109 3.28e-101 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PHKHPGGK_02110 1.29e-41 - - - O - - - OsmC-like protein
PHKHPGGK_02112 1.33e-44 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHKHPGGK_02113 9.04e-162 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHKHPGGK_02114 7.24e-284 - - - S - - - SLAP domain
PHKHPGGK_02115 2.42e-69 - - - S - - - Abi-like protein
PHKHPGGK_02116 2.08e-95 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
PHKHPGGK_02117 2.43e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHKHPGGK_02118 5.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PHKHPGGK_02119 3.23e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHKHPGGK_02120 4.87e-81 yodB - - K - - - Transcriptional regulator, HxlR family
PHKHPGGK_02122 1.08e-161 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_02123 1.48e-139 - - - EGP - - - Major Facilitator
PHKHPGGK_02124 9.16e-301 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
PHKHPGGK_02125 1.38e-95 - - - EGP - - - Major Facilitator
PHKHPGGK_02126 2.58e-45 - - - - - - - -
PHKHPGGK_02129 3.3e-42 - - - - - - - -
PHKHPGGK_02130 3.98e-97 - - - M - - - LysM domain
PHKHPGGK_02131 2.25e-76 - - - L - - - An automated process has identified a potential problem with this gene model
PHKHPGGK_02132 3.19e-165 - - - S - - - Alpha/beta hydrolase family
PHKHPGGK_02133 6.44e-200 epsV - - S - - - glycosyl transferase family 2
PHKHPGGK_02134 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
PHKHPGGK_02135 1.46e-189 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHKHPGGK_02136 1.51e-233 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHKHPGGK_02137 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHKHPGGK_02138 2.29e-112 - - - - - - - -
PHKHPGGK_02139 4.85e-93 - - - K - - - Helix-turn-helix domain, rpiR family
PHKHPGGK_02140 1.91e-28 - - - K - - - Helix-turn-helix domain, rpiR family
PHKHPGGK_02141 1.52e-105 - - - L - - - MgsA AAA+ ATPase C terminal
PHKHPGGK_02142 2.53e-287 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHKHPGGK_02144 2.77e-135 - - - K ko:K06977 - ko00000 acetyltransferase
PHKHPGGK_02145 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
PHKHPGGK_02146 7.25e-309 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
PHKHPGGK_02147 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
PHKHPGGK_02148 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PHKHPGGK_02149 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PHKHPGGK_02150 1.44e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PHKHPGGK_02151 7.8e-10 - - - S - - - Protein of unknown function (DUF3290)
PHKHPGGK_02152 3.85e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
PHKHPGGK_02153 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHKHPGGK_02154 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
PHKHPGGK_02155 1.5e-90 - - - - - - - -
PHKHPGGK_02156 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
PHKHPGGK_02157 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHKHPGGK_02158 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
PHKHPGGK_02159 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_02160 0.0 - - - S - - - SH3-like domain
PHKHPGGK_02161 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHKHPGGK_02162 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PHKHPGGK_02163 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PHKHPGGK_02164 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PHKHPGGK_02165 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
PHKHPGGK_02166 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHKHPGGK_02167 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHKHPGGK_02168 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHKHPGGK_02169 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHKHPGGK_02170 2.72e-238 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PHKHPGGK_02171 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHKHPGGK_02172 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHKHPGGK_02173 8.33e-27 - - - - - - - -
PHKHPGGK_02174 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHKHPGGK_02175 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHKHPGGK_02176 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHKHPGGK_02177 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
PHKHPGGK_02178 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
PHKHPGGK_02179 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
PHKHPGGK_02180 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
PHKHPGGK_02181 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PHKHPGGK_02182 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHKHPGGK_02183 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHKHPGGK_02184 1.63e-154 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
PHKHPGGK_02185 3.27e-170 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
PHKHPGGK_02186 5.49e-301 ymfH - - S - - - Peptidase M16
PHKHPGGK_02187 1.47e-284 ymfF - - S - - - Peptidase M16 inactive domain protein
PHKHPGGK_02188 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PHKHPGGK_02189 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
PHKHPGGK_02190 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHKHPGGK_02191 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
PHKHPGGK_02192 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
PHKHPGGK_02193 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
PHKHPGGK_02194 3.77e-122 - - - S - - - SNARE associated Golgi protein
PHKHPGGK_02195 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
PHKHPGGK_02196 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHKHPGGK_02197 1.91e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHKHPGGK_02198 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
PHKHPGGK_02199 2.44e-143 - - - S - - - CYTH
PHKHPGGK_02200 5.74e-148 yjbH - - Q - - - Thioredoxin
PHKHPGGK_02201 2.63e-205 coiA - - S ko:K06198 - ko00000 Competence protein
PHKHPGGK_02202 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHKHPGGK_02203 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHKHPGGK_02204 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHKHPGGK_02205 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
PHKHPGGK_02206 2.6e-37 - - - - - - - -
PHKHPGGK_02207 1.28e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PHKHPGGK_02208 8.73e-187 - - - S - - - haloacid dehalogenase-like hydrolase
PHKHPGGK_02209 9.01e-287 - - - S ko:K07133 - ko00000 cog cog1373
PHKHPGGK_02210 1.92e-80 yneE - - K - - - Transcriptional regulator
PHKHPGGK_02211 2.18e-122 yneE - - K - - - Transcriptional regulator
PHKHPGGK_02212 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
PHKHPGGK_02213 5.05e-11 - - - - - - - -
PHKHPGGK_02214 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
PHKHPGGK_02216 7.68e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PHKHPGGK_02218 4e-79 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
PHKHPGGK_02219 4.52e-178 - - - L - - - Belongs to the 'phage' integrase family
PHKHPGGK_02220 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHKHPGGK_02221 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_02222 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHKHPGGK_02223 1.45e-119 - - - K - - - Bacterial regulatory proteins, tetR family
PHKHPGGK_02224 2.75e-143 - - - G - - - phosphoglycerate mutase
PHKHPGGK_02225 9.79e-181 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
PHKHPGGK_02226 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
PHKHPGGK_02227 4.66e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHKHPGGK_02228 1.19e-43 - - - S - - - reductase
PHKHPGGK_02229 2.98e-50 - - - S - - - reductase
PHKHPGGK_02230 1.26e-40 - - - S - - - reductase
PHKHPGGK_02231 1.83e-190 yxeH - - S - - - hydrolase
PHKHPGGK_02232 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHKHPGGK_02233 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
PHKHPGGK_02234 1.99e-22 - - - E - - - Pfam:DUF955
PHKHPGGK_02235 4.53e-143 - - - S - - - Fic/DOC family
PHKHPGGK_02236 2.13e-23 - - - L - - - Psort location Cytoplasmic, score
PHKHPGGK_02237 1.02e-34 - - - S - - - Psort location Cytoplasmic, score 8.87
PHKHPGGK_02239 1.79e-99 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHKHPGGK_02240 1.64e-101 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHKHPGGK_02241 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHKHPGGK_02242 1.23e-54 - - - V ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
PHKHPGGK_02244 1.5e-27 - - - S - - - Enterocin A Immunity
PHKHPGGK_02245 1.22e-192 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
PHKHPGGK_02246 3.09e-71 - - - - - - - -
PHKHPGGK_02247 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHKHPGGK_02248 4.28e-187 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
PHKHPGGK_02249 4.52e-126 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHKHPGGK_02250 4.31e-175 - - - - - - - -
PHKHPGGK_02251 5.53e-147 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
PHKHPGGK_02252 8.04e-143 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PHKHPGGK_02253 5.71e-230 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
PHKHPGGK_02254 7.13e-67 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
PHKHPGGK_02255 1.24e-188 - 5.2.1.13 - Q ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
PHKHPGGK_02256 3.43e-79 - - - C - - - 2Fe-2S iron-sulfur cluster binding domain
PHKHPGGK_02257 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHKHPGGK_02258 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHKHPGGK_02259 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
PHKHPGGK_02260 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHKHPGGK_02261 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHKHPGGK_02262 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PHKHPGGK_02263 2.08e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHKHPGGK_02264 1.63e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PHKHPGGK_02265 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHKHPGGK_02266 4.96e-270 - - - S - - - SLAP domain
PHKHPGGK_02267 1.15e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
PHKHPGGK_02268 7.18e-187 - - - E - - - GDSL-like Lipase/Acylhydrolase family
PHKHPGGK_02269 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHKHPGGK_02270 4.16e-51 ynzC - - S - - - UPF0291 protein
PHKHPGGK_02271 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
PHKHPGGK_02272 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHKHPGGK_02273 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHKHPGGK_02274 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
PHKHPGGK_02275 1.74e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
PHKHPGGK_02276 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
PHKHPGGK_02277 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
PHKHPGGK_02278 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PHKHPGGK_02279 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHKHPGGK_02280 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PHKHPGGK_02281 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHKHPGGK_02282 6.38e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHKHPGGK_02283 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PHKHPGGK_02284 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PHKHPGGK_02285 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHKHPGGK_02286 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHKHPGGK_02287 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PHKHPGGK_02288 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PHKHPGGK_02289 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
PHKHPGGK_02290 1.61e-64 ylxQ - - J - - - ribosomal protein
PHKHPGGK_02291 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHKHPGGK_02292 1.67e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHKHPGGK_02293 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHKHPGGK_02294 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PHKHPGGK_02295 6.02e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHKHPGGK_02296 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHKHPGGK_02297 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PHKHPGGK_02298 6.87e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHKHPGGK_02299 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHKHPGGK_02300 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
PHKHPGGK_02301 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PHKHPGGK_02302 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)