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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KNIHOGBD_00001	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KNIHOGBD_00002	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
KNIHOGBD_00005	1.83e-54	-	-	-	C	-	-	-	FMN_bind
KNIHOGBD_00006	4.49e-108	-	-	-	-	-	-	-	-
KNIHOGBD_00007	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
KNIHOGBD_00008	2.06e-111	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
KNIHOGBD_00009	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KNIHOGBD_00010	3.54e-94	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
KNIHOGBD_00011	2.61e-24	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
KNIHOGBD_00012	0.0	-	-	-	L	-	-	-	PLD-like domain
KNIHOGBD_00013	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
KNIHOGBD_00014	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
KNIHOGBD_00015	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
KNIHOGBD_00016	5.51e-35	-	-	-	-	-	-	-	-
KNIHOGBD_00017	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
KNIHOGBD_00018	7.73e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KNIHOGBD_00019	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KNIHOGBD_00020	5.01e-150	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KNIHOGBD_00021	7.68e-63	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KNIHOGBD_00022	1.43e-309	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KNIHOGBD_00023	3.03e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KNIHOGBD_00024	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
KNIHOGBD_00025	4.82e-102	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
KNIHOGBD_00026	5.44e-299	-	-	-	V	-	-	-	N-6 DNA Methylase
KNIHOGBD_00027	4.17e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KNIHOGBD_00028	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00029	4.73e-72	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
KNIHOGBD_00030	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KNIHOGBD_00031	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNIHOGBD_00033	1.23e-175	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_00034	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KNIHOGBD_00035	8.41e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KNIHOGBD_00037	4.97e-45	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
KNIHOGBD_00038	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
KNIHOGBD_00039	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
KNIHOGBD_00040	1.34e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KNIHOGBD_00041	6.21e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KNIHOGBD_00042	1.53e-142	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
KNIHOGBD_00043	4.83e-107	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KNIHOGBD_00044	1.42e-57	-	-	-	-	-	-	-	-
KNIHOGBD_00045	4.65e-14	-	-	-	-	-	-	-	-
KNIHOGBD_00046	7.81e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
KNIHOGBD_00047	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
KNIHOGBD_00048	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
KNIHOGBD_00065	2.25e-90	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KNIHOGBD_00068	1.6e-16	-	-	-	-	-	-	-	-
KNIHOGBD_00070	2.85e-34	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00071	4.58e-26	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00072	1.05e-159	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
KNIHOGBD_00078	3.84e-81	-	-	-	S	-	-	-	ERF superfamily
KNIHOGBD_00079	1.95e-71	-	-	-	S	-	-	-	calcium ion binding
KNIHOGBD_00080	6.6e-107	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
KNIHOGBD_00085	1.87e-55	-	-	-	S	-	-	-	ASCH domain
KNIHOGBD_00086	2.48e-129	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
KNIHOGBD_00088	6.14e-41	-	-	-	-	-	-	-	-
KNIHOGBD_00089	9.09e-143	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
KNIHOGBD_00090	1.26e-108	-	-	-	L	-	-	-	transposase activity
KNIHOGBD_00091	1.01e-270	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
KNIHOGBD_00092	4.77e-269	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KNIHOGBD_00093	1.32e-214	-	-	-	S	-	-	-	Phage minor capsid protein 2
KNIHOGBD_00095	1.89e-53	-	-	-	S	-	-	-	Phage minor structural protein GP20
KNIHOGBD_00096	6.19e-195	gpG	-	-	-	-	-	-	-
KNIHOGBD_00097	6.65e-58	-	-	-	-	-	-	-	-
KNIHOGBD_00098	2.27e-52	-	-	-	S	-	-	-	Minor capsid protein
KNIHOGBD_00099	1.92e-41	-	-	-	S	-	-	-	Minor capsid protein
KNIHOGBD_00100	1.67e-67	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
KNIHOGBD_00101	1.61e-105	-	-	-	N	-	-	-	domain, Protein
KNIHOGBD_00102	2.11e-45	-	-	-	-	-	-	-	-
KNIHOGBD_00103	4.82e-110	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
KNIHOGBD_00104	0.0	-	-	-	D	-	-	-	domain protein
KNIHOGBD_00105	7.46e-139	-	-	-	S	-	-	-	phage tail
KNIHOGBD_00106	0.0	-	-	-	S	-	-	-	Phage minor structural protein
KNIHOGBD_00116	1.8e-49	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
KNIHOGBD_00117	7.31e-130	-	-	-	M	-	-	-	hydrolase, family 25
KNIHOGBD_00120	5.1e-09	-	-	-	-	-	-	-	-
KNIHOGBD_00123	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_00124	1.02e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNIHOGBD_00125	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
KNIHOGBD_00126	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
KNIHOGBD_00127	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KNIHOGBD_00128	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KNIHOGBD_00129	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_00130	1.86e-91	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_00131	3.53e-35	-	-	-	C	ko:K21832	-	ko00000	nitric oxide dioxygenase activity
KNIHOGBD_00132	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
KNIHOGBD_00133	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KNIHOGBD_00134	5.17e-79	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KNIHOGBD_00135	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNIHOGBD_00136	1.21e-204	-	-	-	-	-	-	-	-
KNIHOGBD_00137	2.79e-19	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
KNIHOGBD_00138	1.92e-42	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
KNIHOGBD_00140	2.76e-46	-	-	-	-	-	-	-	-
KNIHOGBD_00141	1.92e-147	-	-	-	S	-	-	-	interspecies interaction between organisms
KNIHOGBD_00142	1.64e-215	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00143	2.73e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KNIHOGBD_00144	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KNIHOGBD_00145	2.3e-169	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
KNIHOGBD_00146	4.4e-165	-	-	-	S	-	-	-	PAS domain
KNIHOGBD_00148	2.62e-69	-	-	-	-	-	-	-	-
KNIHOGBD_00149	6.31e-84	-	-	-	-	-	-	-	-
KNIHOGBD_00150	2.41e-39	-	-	-	-	-	-	-	-
KNIHOGBD_00153	4.82e-144	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00154	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
KNIHOGBD_00156	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
KNIHOGBD_00157	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KNIHOGBD_00158	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KNIHOGBD_00159	3.73e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KNIHOGBD_00160	2.29e-184	-	-	-	K	-	-	-	LysR substrate binding domain
KNIHOGBD_00161	4.12e-205	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
KNIHOGBD_00162	8.45e-102	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
KNIHOGBD_00163	2.5e-136	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
KNIHOGBD_00164	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
KNIHOGBD_00165	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIHOGBD_00166	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIHOGBD_00167	2.47e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNIHOGBD_00168	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNIHOGBD_00169	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KNIHOGBD_00170	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KNIHOGBD_00171	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KNIHOGBD_00172	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KNIHOGBD_00173	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNIHOGBD_00174	3.8e-80	-	-	-	-	-	-	-	-
KNIHOGBD_00175	4.8e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KNIHOGBD_00176	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNIHOGBD_00177	5.26e-15	-	-	-	-	-	-	-	-
KNIHOGBD_00179	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
KNIHOGBD_00180	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
KNIHOGBD_00181	2.41e-66	-	-	-	-	-	-	-	-
KNIHOGBD_00182	7.91e-14	-	-	-	-	-	-	-	-
KNIHOGBD_00183	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
KNIHOGBD_00184	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KNIHOGBD_00185	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00186	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KNIHOGBD_00187	9.9e-30	-	-	-	-	-	-	-	-
KNIHOGBD_00188	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
KNIHOGBD_00189	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
KNIHOGBD_00190	4.21e-213	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
KNIHOGBD_00191	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
KNIHOGBD_00192	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KNIHOGBD_00193	2.56e-196	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KNIHOGBD_00194	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KNIHOGBD_00195	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
KNIHOGBD_00196	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KNIHOGBD_00197	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KNIHOGBD_00198	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KNIHOGBD_00199	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KNIHOGBD_00200	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00201	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNIHOGBD_00202	5.31e-206	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KNIHOGBD_00203	2.57e-223	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KNIHOGBD_00204	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KNIHOGBD_00205	1.86e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNIHOGBD_00206	8.21e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNIHOGBD_00207	3.87e-73	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
KNIHOGBD_00208	2.76e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KNIHOGBD_00209	4.31e-175	-	-	-	-	-	-	-	-
KNIHOGBD_00210	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KNIHOGBD_00211	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KNIHOGBD_00212	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
KNIHOGBD_00213	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_00214	1.19e-19	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_00215	4.06e-109	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KNIHOGBD_00216	1.04e-94	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KNIHOGBD_00217	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KNIHOGBD_00218	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNIHOGBD_00219	3.79e-158	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KNIHOGBD_00220	7.88e-59	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
KNIHOGBD_00221	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_00222	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KNIHOGBD_00223	8.97e-47	-	-	-	-	-	-	-	-
KNIHOGBD_00224	4.93e-43	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
KNIHOGBD_00225	2.51e-46	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
KNIHOGBD_00226	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
KNIHOGBD_00227	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
KNIHOGBD_00228	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
KNIHOGBD_00229	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KNIHOGBD_00230	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
KNIHOGBD_00231	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
KNIHOGBD_00232	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
KNIHOGBD_00233	0.0	cadA	-	-	P	-	-	-	P-type ATPase
KNIHOGBD_00234	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
KNIHOGBD_00235	5.11e-265	-	-	-	S	-	-	-	Membrane
KNIHOGBD_00236	1.42e-58	-	-	-	-	-	-	-	-
KNIHOGBD_00237	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KNIHOGBD_00238	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNIHOGBD_00239	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
KNIHOGBD_00240	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNIHOGBD_00241	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNIHOGBD_00242	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_00243	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
KNIHOGBD_00244	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_00245	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KNIHOGBD_00246	1.96e-49	-	-	-	-	-	-	-	-
KNIHOGBD_00247	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00248	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00249	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00250	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KNIHOGBD_00251	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
KNIHOGBD_00252	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KNIHOGBD_00253	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KNIHOGBD_00254	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KNIHOGBD_00255	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_00256	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
KNIHOGBD_00258	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KNIHOGBD_00259	6.45e-291	-	-	-	E	-	-	-	amino acid
KNIHOGBD_00260	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KNIHOGBD_00261	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
KNIHOGBD_00264	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNIHOGBD_00265	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNIHOGBD_00266	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNIHOGBD_00267	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_00268	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNIHOGBD_00269	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KNIHOGBD_00271	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KNIHOGBD_00272	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_00273	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_00274	7.02e-36	-	-	-	-	-	-	-	-
KNIHOGBD_00275	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KNIHOGBD_00276	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KNIHOGBD_00277	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KNIHOGBD_00278	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KNIHOGBD_00279	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KNIHOGBD_00280	4.24e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
KNIHOGBD_00281	0.0	yhaN	-	-	L	-	-	-	AAA domain
KNIHOGBD_00282	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIHOGBD_00284	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
KNIHOGBD_00285	0.0	-	-	-	-	-	-	-	-
KNIHOGBD_00286	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
KNIHOGBD_00287	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KNIHOGBD_00288	2.41e-41	-	-	-	-	-	-	-	-
KNIHOGBD_00289	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
KNIHOGBD_00290	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00291	1.63e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KNIHOGBD_00292	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KNIHOGBD_00294	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
KNIHOGBD_00295	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNIHOGBD_00296	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KNIHOGBD_00297	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
KNIHOGBD_00298	6.21e-136	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_00299	7.87e-54	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_00300	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
KNIHOGBD_00301	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
KNIHOGBD_00302	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KNIHOGBD_00303	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KNIHOGBD_00304	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KNIHOGBD_00305	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNIHOGBD_00306	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KNIHOGBD_00307	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNIHOGBD_00308	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNIHOGBD_00309	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
KNIHOGBD_00310	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KNIHOGBD_00311	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNIHOGBD_00312	5.69e-179	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KNIHOGBD_00313	1.14e-208	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
KNIHOGBD_00314	2.14e-48	-	-	-	-	-	-	-	-
KNIHOGBD_00315	1.47e-70	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNIHOGBD_00316	1.41e-97	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KNIHOGBD_00317	3.28e-101	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KNIHOGBD_00318	1.48e-136	-	-	-	L	-	-	-	PFAM Integrase catalytic
KNIHOGBD_00319	2.28e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KNIHOGBD_00320	2.87e-107	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_00321	3.54e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
KNIHOGBD_00322	6.24e-210	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_00323	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KNIHOGBD_00324	3.05e-15	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KNIHOGBD_00325	4.49e-156	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KNIHOGBD_00326	2.74e-06	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_00327	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00328	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00331	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KNIHOGBD_00334	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNIHOGBD_00335	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_00337	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KNIHOGBD_00338	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KNIHOGBD_00339	1.32e-151	-	-	-	S	-	-	-	Putative esterase
KNIHOGBD_00340	1.81e-270	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KNIHOGBD_00341	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KNIHOGBD_00342	3.75e-168	-	-	-	K	-	-	-	rpiR family
KNIHOGBD_00343	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
KNIHOGBD_00344	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
KNIHOGBD_00345	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KNIHOGBD_00346	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KNIHOGBD_00347	8.7e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KNIHOGBD_00348	1.38e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KNIHOGBD_00349	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KNIHOGBD_00350	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KNIHOGBD_00351	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KNIHOGBD_00352	9.32e-109	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
KNIHOGBD_00353	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
KNIHOGBD_00354	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
KNIHOGBD_00355	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KNIHOGBD_00356	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KNIHOGBD_00357	4.57e-254	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_00358	4.84e-42	-	-	-	-	-	-	-	-
KNIHOGBD_00359	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KNIHOGBD_00360	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KNIHOGBD_00361	2.03e-193	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KNIHOGBD_00362	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNIHOGBD_00363	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KNIHOGBD_00364	4.65e-157	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
KNIHOGBD_00365	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KNIHOGBD_00367	1.45e-133	-	-	-	-	-	-	-	-
KNIHOGBD_00368	9e-132	-	-	-	L	-	-	-	Integrase
KNIHOGBD_00369	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
KNIHOGBD_00370	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
KNIHOGBD_00371	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
KNIHOGBD_00372	6.1e-186	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_00373	2.55e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_00374	1.74e-63	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KNIHOGBD_00375	7.47e-164	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_00376	7.3e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
KNIHOGBD_00377	3.59e-315	-	-	-	G	-	-	-	MFS/sugar transport protein
KNIHOGBD_00378	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
KNIHOGBD_00379	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
KNIHOGBD_00380	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00381	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_00382	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00383	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00384	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
KNIHOGBD_00385	2.09e-110	-	-	-	-	-	-	-	-
KNIHOGBD_00386	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KNIHOGBD_00387	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KNIHOGBD_00388	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
KNIHOGBD_00389	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNIHOGBD_00390	1.82e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNIHOGBD_00391	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KNIHOGBD_00392	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
KNIHOGBD_00393	1.1e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
KNIHOGBD_00394	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KNIHOGBD_00395	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
KNIHOGBD_00396	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
KNIHOGBD_00397	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KNIHOGBD_00398	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
KNIHOGBD_00399	7.44e-189	-	-	-	S	-	-	-	hydrolase
KNIHOGBD_00400	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KNIHOGBD_00401	8.04e-189	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
KNIHOGBD_00402	1.52e-103	-	-	-	-	-	-	-	-
KNIHOGBD_00403	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KNIHOGBD_00404	1.76e-52	-	-	-	-	-	-	-	-
KNIHOGBD_00405	2.14e-154	-	-	-	C	-	-	-	nitroreductase
KNIHOGBD_00406	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
KNIHOGBD_00407	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KNIHOGBD_00408	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KNIHOGBD_00409	1.42e-113	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
KNIHOGBD_00410	1.67e-66	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
KNIHOGBD_00411	6.74e-269	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KNIHOGBD_00412	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KNIHOGBD_00413	2.14e-103	-	-	-	-	-	-	-	-
KNIHOGBD_00414	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
KNIHOGBD_00415	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
KNIHOGBD_00416	1.21e-40	-	-	-	-	-	-	-	-
KNIHOGBD_00417	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
KNIHOGBD_00418	1.2e-248	pbpX1	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_00419	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNIHOGBD_00420	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KNIHOGBD_00421	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KNIHOGBD_00422	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNIHOGBD_00423	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KNIHOGBD_00424	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNIHOGBD_00425	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KNIHOGBD_00426	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KNIHOGBD_00427	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KNIHOGBD_00428	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
KNIHOGBD_00429	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
KNIHOGBD_00430	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KNIHOGBD_00431	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNIHOGBD_00432	2.49e-282	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KNIHOGBD_00433	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNIHOGBD_00434	5.43e-191	-	-	-	-	-	-	-	-
KNIHOGBD_00435	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNIHOGBD_00436	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNIHOGBD_00437	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KNIHOGBD_00438	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KNIHOGBD_00439	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KNIHOGBD_00440	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
KNIHOGBD_00441	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KNIHOGBD_00442	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNIHOGBD_00443	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
KNIHOGBD_00444	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
KNIHOGBD_00445	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KNIHOGBD_00446	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KNIHOGBD_00447	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KNIHOGBD_00448	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KNIHOGBD_00449	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNIHOGBD_00450	0.0	-	-	-	L	-	-	-	Transposase DDE domain
KNIHOGBD_00451	5.93e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KNIHOGBD_00452	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KNIHOGBD_00453	1.45e-34	-	-	-	K	-	-	-	FCD
KNIHOGBD_00455	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
KNIHOGBD_00458	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
KNIHOGBD_00459	7.27e-42	-	-	-	-	-	-	-	-
KNIHOGBD_00460	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KNIHOGBD_00461	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KNIHOGBD_00462	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KNIHOGBD_00463	7.2e-40	-	-	-	-	-	-	-	-
KNIHOGBD_00464	5.49e-46	-	-	-	-	-	-	-	-
KNIHOGBD_00465	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KNIHOGBD_00466	2.52e-76	-	-	-	-	-	-	-	-
KNIHOGBD_00467	0.0	-	-	-	S	-	-	-	ABC transporter
KNIHOGBD_00468	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
KNIHOGBD_00469	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KNIHOGBD_00470	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
KNIHOGBD_00471	1.16e-101	-	-	-	-	-	-	-	-
KNIHOGBD_00472	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNIHOGBD_00473	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
KNIHOGBD_00474	5.48e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KNIHOGBD_00475	8.77e-144	-	-	-	-	-	-	-	-
KNIHOGBD_00476	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
KNIHOGBD_00477	4.52e-56	-	-	-	-	-	-	-	-
KNIHOGBD_00478	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
KNIHOGBD_00479	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
KNIHOGBD_00480	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
KNIHOGBD_00481	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
KNIHOGBD_00482	3.01e-54	-	-	-	-	-	-	-	-
KNIHOGBD_00483	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KNIHOGBD_00484	6.72e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNIHOGBD_00487	8.14e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KNIHOGBD_00488	5.52e-187	epsB	-	-	M	-	-	-	biosynthesis protein
KNIHOGBD_00489	5.61e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KNIHOGBD_00490	2.22e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KNIHOGBD_00491	2.91e-140	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
KNIHOGBD_00492	9.92e-152	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KNIHOGBD_00494	3.52e-103	epsIIG	1.1.1.133	-	S	ko:K00067,ko:K07011	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Glycosyltransferase, group 2 family protein
KNIHOGBD_00495	1.81e-91	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
KNIHOGBD_00496	1.63e-52	-	-	-	M	-	-	-	Glycosyl transferase family 2
KNIHOGBD_00497	1.33e-44	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_00499	1.29e-41	-	-	-	O	-	-	-	OsmC-like protein
KNIHOGBD_00500	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
KNIHOGBD_00501	1.45e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
KNIHOGBD_00502	1.08e-229	-	-	-	L	-	-	-	DDE superfamily endonuclease
KNIHOGBD_00503	2.43e-55	-	-	-	-	-	-	-	-
KNIHOGBD_00504	1.35e-56	-	-	-	-	-	-	-	-
KNIHOGBD_00505	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
KNIHOGBD_00506	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KNIHOGBD_00507	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KNIHOGBD_00508	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KNIHOGBD_00509	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
KNIHOGBD_00510	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
KNIHOGBD_00511	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KNIHOGBD_00512	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNIHOGBD_00513	1.48e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNIHOGBD_00514	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNIHOGBD_00515	6.55e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNIHOGBD_00516	2.48e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNIHOGBD_00517	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNIHOGBD_00518	5.87e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KNIHOGBD_00519	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNIHOGBD_00520	1.66e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KNIHOGBD_00521	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KNIHOGBD_00522	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNIHOGBD_00523	7.02e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KNIHOGBD_00524	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
KNIHOGBD_00527	7.95e-250	ampC	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_00528	3.26e-274	-	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_00529	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KNIHOGBD_00530	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
KNIHOGBD_00531	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNIHOGBD_00532	0.0	yclK	-	-	T	-	-	-	Histidine kinase
KNIHOGBD_00533	4.96e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KNIHOGBD_00534	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
KNIHOGBD_00535	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KNIHOGBD_00536	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KNIHOGBD_00537	3e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
KNIHOGBD_00538	3.68e-14	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNIHOGBD_00539	6.88e-11	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
KNIHOGBD_00541	1.94e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
KNIHOGBD_00542	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
KNIHOGBD_00543	4.3e-175	-	-	-	S	-	-	-	Alpha/beta hydrolase family
KNIHOGBD_00544	2.95e-123	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KNIHOGBD_00545	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNIHOGBD_00546	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
KNIHOGBD_00547	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KNIHOGBD_00548	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KNIHOGBD_00549	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KNIHOGBD_00550	9.48e-31	-	-	-	-	-	-	-	-
KNIHOGBD_00551	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
KNIHOGBD_00552	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
KNIHOGBD_00553	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
KNIHOGBD_00554	5.79e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNIHOGBD_00555	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
KNIHOGBD_00556	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
KNIHOGBD_00557	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KNIHOGBD_00558	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KNIHOGBD_00559	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNIHOGBD_00560	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KNIHOGBD_00561	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KNIHOGBD_00562	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
KNIHOGBD_00563	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNIHOGBD_00564	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KNIHOGBD_00565	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNIHOGBD_00566	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNIHOGBD_00567	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
KNIHOGBD_00568	1.12e-136	-	-	-	M	-	-	-	family 8
KNIHOGBD_00569	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNIHOGBD_00570	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KNIHOGBD_00571	6.15e-36	-	-	-	-	-	-	-	-
KNIHOGBD_00572	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
KNIHOGBD_00573	9.32e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
KNIHOGBD_00574	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KNIHOGBD_00575	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNIHOGBD_00577	5.61e-118	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_00578	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KNIHOGBD_00579	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNIHOGBD_00580	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNIHOGBD_00581	1.31e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KNIHOGBD_00582	2.82e-228	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00583	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KNIHOGBD_00584	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
KNIHOGBD_00586	1.16e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_00587	8.57e-202	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
KNIHOGBD_00588	1.03e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KNIHOGBD_00589	2.47e-243	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KNIHOGBD_00590	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KNIHOGBD_00592	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KNIHOGBD_00593	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIHOGBD_00594	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KNIHOGBD_00595	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KNIHOGBD_00596	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KNIHOGBD_00597	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNIHOGBD_00598	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
KNIHOGBD_00599	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNIHOGBD_00600	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNIHOGBD_00601	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNIHOGBD_00602	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNIHOGBD_00603	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KNIHOGBD_00604	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KNIHOGBD_00605	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KNIHOGBD_00606	2.19e-100	-	-	-	S	-	-	-	ASCH
KNIHOGBD_00607	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KNIHOGBD_00608	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KNIHOGBD_00609	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNIHOGBD_00610	4.41e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNIHOGBD_00611	1.06e-308	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNIHOGBD_00612	1.98e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KNIHOGBD_00613	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KNIHOGBD_00614	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KNIHOGBD_00615	4.33e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KNIHOGBD_00616	3.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KNIHOGBD_00617	2.2e-41	-	-	-	-	-	-	-	-
KNIHOGBD_00618	8.76e-146	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KNIHOGBD_00621	2.79e-10	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00624	1.7e-23	-	-	-	-	-	-	-	-
KNIHOGBD_00625	6.73e-97	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
KNIHOGBD_00632	8.93e-33	-	-	-	S	-	-	-	HNH endonuclease
KNIHOGBD_00633	9.54e-88	-	-	-	S	-	-	-	AAA domain
KNIHOGBD_00635	2.27e-187	-	-	-	L	-	-	-	Helicase C-terminal domain protein
KNIHOGBD_00638	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
KNIHOGBD_00650	2.71e-49	-	-	-	S	-	-	-	VRR_NUC
KNIHOGBD_00654	1.71e-72	-	-	-	S	-	-	-	Phage terminase, small subunit
KNIHOGBD_00656	2.37e-263	-	-	-	S	-	-	-	Phage Terminase
KNIHOGBD_00658	4.25e-167	-	-	-	S	-	-	-	Phage portal protein
KNIHOGBD_00659	1.59e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
KNIHOGBD_00660	8.25e-69	-	-	-	S	-	-	-	Phage capsid family
KNIHOGBD_00668	6.67e-135	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
KNIHOGBD_00670	1.61e-155	-	-	-	S	-	-	-	Phage minor structural protein
KNIHOGBD_00679	6.5e-51	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
KNIHOGBD_00680	8.02e-127	-	-	-	M	-	-	-	hydrolase, family 25
KNIHOGBD_00682	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KNIHOGBD_00683	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KNIHOGBD_00684	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
KNIHOGBD_00685	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNIHOGBD_00686	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KNIHOGBD_00687	1.04e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNIHOGBD_00688	7.02e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KNIHOGBD_00689	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KNIHOGBD_00690	1.53e-218	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00691	3.06e-181	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KNIHOGBD_00692	5.92e-90	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00693	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KNIHOGBD_00694	3.85e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KNIHOGBD_00695	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KNIHOGBD_00696	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KNIHOGBD_00697	6.64e-94	-	-	-	-	-	-	-	-
KNIHOGBD_00698	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
KNIHOGBD_00699	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
KNIHOGBD_00700	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNIHOGBD_00701	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
KNIHOGBD_00702	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KNIHOGBD_00703	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KNIHOGBD_00704	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
KNIHOGBD_00705	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
KNIHOGBD_00706	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
KNIHOGBD_00707	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KNIHOGBD_00708	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KNIHOGBD_00709	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00710	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
KNIHOGBD_00711	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KNIHOGBD_00712	8.6e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
KNIHOGBD_00713	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KNIHOGBD_00714	1.05e-67	-	-	-	-	-	-	-	-
KNIHOGBD_00715	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00717	2.45e-62	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
KNIHOGBD_00718	2.25e-72	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
KNIHOGBD_00722	3.92e-153	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
KNIHOGBD_00723	1.37e-287	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
KNIHOGBD_00724	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
KNIHOGBD_00725	3.81e-18	-	-	-	S	-	-	-	CsbD-like
KNIHOGBD_00726	4.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KNIHOGBD_00727	8.66e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
KNIHOGBD_00728	2.26e-215	degV1	-	-	S	-	-	-	DegV family
KNIHOGBD_00729	5.56e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
KNIHOGBD_00730	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KNIHOGBD_00731	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KNIHOGBD_00732	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KNIHOGBD_00733	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNIHOGBD_00734	4.83e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNIHOGBD_00735	6.72e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KNIHOGBD_00736	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNIHOGBD_00737	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNIHOGBD_00738	4.22e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNIHOGBD_00739	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
KNIHOGBD_00740	8.11e-245	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KNIHOGBD_00741	9.14e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNIHOGBD_00742	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KNIHOGBD_00743	4.24e-46	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KNIHOGBD_00745	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KNIHOGBD_00746	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
KNIHOGBD_00747	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
KNIHOGBD_00748	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
KNIHOGBD_00749	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
KNIHOGBD_00750	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KNIHOGBD_00751	1.38e-309	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KNIHOGBD_00752	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KNIHOGBD_00753	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KNIHOGBD_00754	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KNIHOGBD_00755	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
KNIHOGBD_00756	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KNIHOGBD_00757	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00758	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
KNIHOGBD_00759	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KNIHOGBD_00760	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KNIHOGBD_00761	3.36e-42	-	-	-	-	-	-	-	-
KNIHOGBD_00762	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
KNIHOGBD_00763	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_00764	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KNIHOGBD_00765	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
KNIHOGBD_00766	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
KNIHOGBD_00767	7.88e-79	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
KNIHOGBD_00768	2.19e-73	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KNIHOGBD_00769	5.55e-20	-	-	-	K	-	-	-	LytTr DNA-binding domain
KNIHOGBD_00770	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KNIHOGBD_00771	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
KNIHOGBD_00772	1.1e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KNIHOGBD_00773	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KNIHOGBD_00774	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
KNIHOGBD_00775	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KNIHOGBD_00776	2.42e-33	-	-	-	-	-	-	-	-
KNIHOGBD_00777	3.43e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNIHOGBD_00778	2.32e-234	-	-	-	S	-	-	-	AAA domain
KNIHOGBD_00779	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KNIHOGBD_00780	1.11e-69	-	-	-	-	-	-	-	-
KNIHOGBD_00781	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
KNIHOGBD_00782	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNIHOGBD_00783	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNIHOGBD_00784	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KNIHOGBD_00785	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNIHOGBD_00786	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNIHOGBD_00787	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
KNIHOGBD_00788	1.19e-45	-	-	-	-	-	-	-	-
KNIHOGBD_00789	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KNIHOGBD_00790	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNIHOGBD_00791	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KNIHOGBD_00792	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KNIHOGBD_00793	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNIHOGBD_00794	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KNIHOGBD_00795	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KNIHOGBD_00796	2.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KNIHOGBD_00797	1.56e-217	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KNIHOGBD_00798	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
KNIHOGBD_00799	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
KNIHOGBD_00800	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
KNIHOGBD_00801	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KNIHOGBD_00802	4.04e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KNIHOGBD_00803	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_00804	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00805	1.4e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
KNIHOGBD_00806	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
KNIHOGBD_00807	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
KNIHOGBD_00808	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
KNIHOGBD_00809	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
KNIHOGBD_00810	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
KNIHOGBD_00811	9.69e-25	-	-	-	-	-	-	-	-
KNIHOGBD_00812	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
KNIHOGBD_00813	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KNIHOGBD_00814	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
KNIHOGBD_00815	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KNIHOGBD_00816	1.16e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KNIHOGBD_00817	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KNIHOGBD_00818	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00819	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KNIHOGBD_00820	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KNIHOGBD_00821	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
KNIHOGBD_00822	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
KNIHOGBD_00823	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
KNIHOGBD_00824	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
KNIHOGBD_00826	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KNIHOGBD_00827	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KNIHOGBD_00828	6.72e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_00829	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
KNIHOGBD_00830	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
KNIHOGBD_00831	1.2e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KNIHOGBD_00833	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
KNIHOGBD_00834	2.27e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIHOGBD_00835	7.01e-103	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KNIHOGBD_00836	1.9e-158	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
KNIHOGBD_00837	2.42e-163	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
KNIHOGBD_00838	4.9e-180	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNIHOGBD_00839	3.44e-300	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
KNIHOGBD_00840	7.28e-80	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
KNIHOGBD_00841	3.17e-67	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KNIHOGBD_00842	2.53e-268	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KNIHOGBD_00843	1.4e-137	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KNIHOGBD_00844	2.77e-177	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KNIHOGBD_00845	4.22e-41	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNIHOGBD_00846	1.98e-47	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNIHOGBD_00847	9.89e-112	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNIHOGBD_00848	8.44e-65	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KNIHOGBD_00849	1.67e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
KNIHOGBD_00850	6.14e-107	-	-	-	-	-	-	-	-
KNIHOGBD_00851	2.57e-206	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_00852	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
KNIHOGBD_00853	1.83e-103	-	-	-	S	-	-	-	AAA domain
KNIHOGBD_00854	6.42e-73	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KNIHOGBD_00855	1.89e-23	-	-	-	-	-	-	-	-
KNIHOGBD_00856	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
KNIHOGBD_00857	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
KNIHOGBD_00858	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
KNIHOGBD_00859	4.48e-34	-	-	-	-	-	-	-	-
KNIHOGBD_00860	1.07e-35	-	-	-	-	-	-	-	-
KNIHOGBD_00861	1.95e-45	-	-	-	-	-	-	-	-
KNIHOGBD_00862	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
KNIHOGBD_00863	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KNIHOGBD_00864	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNIHOGBD_00865	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
KNIHOGBD_00866	8.32e-157	vanR	-	-	K	-	-	-	response regulator
KNIHOGBD_00868	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KNIHOGBD_00869	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00870	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_00871	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KNIHOGBD_00872	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KNIHOGBD_00873	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
KNIHOGBD_00874	4.28e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KNIHOGBD_00875	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
KNIHOGBD_00876	5.86e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KNIHOGBD_00877	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KNIHOGBD_00878	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
KNIHOGBD_00879	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
KNIHOGBD_00880	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNIHOGBD_00881	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KNIHOGBD_00882	8.81e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KNIHOGBD_00883	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNIHOGBD_00884	2.22e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KNIHOGBD_00885	8.31e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNIHOGBD_00886	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KNIHOGBD_00887	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KNIHOGBD_00888	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KNIHOGBD_00889	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KNIHOGBD_00890	8.74e-62	-	-	-	-	-	-	-	-
KNIHOGBD_00891	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KNIHOGBD_00892	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNIHOGBD_00893	1.02e-29	-	-	-	S	-	-	-	Alpha beta hydrolase
KNIHOGBD_00894	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
KNIHOGBD_00895	8.51e-50	-	-	-	-	-	-	-	-
KNIHOGBD_00896	4.3e-66	-	-	-	-	-	-	-	-
KNIHOGBD_00897	2.13e-51	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KNIHOGBD_00898	1.03e-124	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KNIHOGBD_00899	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00900	2.35e-101	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
KNIHOGBD_00901	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
KNIHOGBD_00902	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
KNIHOGBD_00903	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
KNIHOGBD_00904	1.09e-74	-	-	-	-	-	-	-	-
KNIHOGBD_00905	6.77e-111	-	-	-	-	-	-	-	-
KNIHOGBD_00906	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
KNIHOGBD_00907	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
KNIHOGBD_00908	9.07e-143	-	-	-	-	-	-	-	-
KNIHOGBD_00909	1.32e-137	-	-	-	-	-	-	-	-
KNIHOGBD_00910	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
KNIHOGBD_00911	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
KNIHOGBD_00912	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
KNIHOGBD_00913	5.51e-47	-	-	-	-	-	-	-	-
KNIHOGBD_00914	1.03e-07	-	-	-	-	-	-	-	-
KNIHOGBD_00915	1.02e-200	-	-	-	-	-	-	-	-
KNIHOGBD_00918	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
KNIHOGBD_00919	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KNIHOGBD_00920	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
KNIHOGBD_00921	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
KNIHOGBD_00922	3.65e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KNIHOGBD_00923	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
KNIHOGBD_00924	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
KNIHOGBD_00925	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KNIHOGBD_00926	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNIHOGBD_00927	1e-131	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KNIHOGBD_00928	4.06e-88	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00929	1.33e-92	-	-	-	-	-	-	-	-
KNIHOGBD_00930	1.81e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNIHOGBD_00931	2.05e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KNIHOGBD_00932	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
KNIHOGBD_00933	8.93e-194	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNIHOGBD_00934	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNIHOGBD_00935	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
KNIHOGBD_00936	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNIHOGBD_00937	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
KNIHOGBD_00938	1.71e-173	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
KNIHOGBD_00939	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
KNIHOGBD_00940	1.5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
KNIHOGBD_00941	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KNIHOGBD_00942	7.04e-145	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
KNIHOGBD_00944	1.17e-143	-	-	-	-	-	-	-	-
KNIHOGBD_00945	8.08e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNIHOGBD_00946	3.4e-93	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KNIHOGBD_00947	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KNIHOGBD_00948	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KNIHOGBD_00949	7.1e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KNIHOGBD_00950	7.82e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNIHOGBD_00951	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNIHOGBD_00952	2.64e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNIHOGBD_00953	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
KNIHOGBD_00954	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
KNIHOGBD_00955	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
KNIHOGBD_00956	7.82e-80	-	-	-	-	-	-	-	-
KNIHOGBD_00957	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
KNIHOGBD_00958	6.58e-175	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KNIHOGBD_00960	4.51e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
KNIHOGBD_00961	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KNIHOGBD_00962	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KNIHOGBD_00964	1.04e-41	-	-	-	-	-	-	-	-
KNIHOGBD_00965	2.77e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
KNIHOGBD_00966	1.25e-17	-	-	-	-	-	-	-	-
KNIHOGBD_00967	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00968	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00969	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_00970	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
KNIHOGBD_00971	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
KNIHOGBD_00972	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KNIHOGBD_00973	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
KNIHOGBD_00974	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
KNIHOGBD_00975	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KNIHOGBD_00977	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
KNIHOGBD_00979	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KNIHOGBD_00980	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KNIHOGBD_00981	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KNIHOGBD_00982	1.43e-186	-	-	-	K	-	-	-	SIS domain
KNIHOGBD_00983	1.36e-308	slpX	-	-	S	-	-	-	SLAP domain
KNIHOGBD_00984	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
KNIHOGBD_00985	1.18e-13	-	-	-	-	-	-	-	-
KNIHOGBD_00986	4.41e-305	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KNIHOGBD_00989	7.83e-303	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_00990	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_00991	2.17e-232	-	-	-	-	-	-	-	-
KNIHOGBD_00992	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
KNIHOGBD_00993	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
KNIHOGBD_00994	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KNIHOGBD_00995	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
KNIHOGBD_00996	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNIHOGBD_00997	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KNIHOGBD_00998	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KNIHOGBD_00999	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KNIHOGBD_01000	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KNIHOGBD_01001	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KNIHOGBD_01002	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
KNIHOGBD_01003	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KNIHOGBD_01005	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
KNIHOGBD_01006	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KNIHOGBD_01007	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNIHOGBD_01008	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
KNIHOGBD_01009	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNIHOGBD_01010	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KNIHOGBD_01011	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNIHOGBD_01012	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
KNIHOGBD_01013	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KNIHOGBD_01014	1.46e-75	-	-	-	-	-	-	-	-
KNIHOGBD_01015	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KNIHOGBD_01016	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KNIHOGBD_01017	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_01018	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNIHOGBD_01019	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01024	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_01025	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KNIHOGBD_01026	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KNIHOGBD_01027	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_01028	5.57e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KNIHOGBD_01029	4.52e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KNIHOGBD_01030	1.55e-29	-	-	-	-	-	-	-	-
KNIHOGBD_01031	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNIHOGBD_01032	4.13e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KNIHOGBD_01033	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KNIHOGBD_01034	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KNIHOGBD_01035	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KNIHOGBD_01036	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNIHOGBD_01037	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KNIHOGBD_01038	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNIHOGBD_01039	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KNIHOGBD_01040	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNIHOGBD_01041	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KNIHOGBD_01042	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
KNIHOGBD_01043	1.74e-274	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNIHOGBD_01044	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNIHOGBD_01045	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KNIHOGBD_01046	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KNIHOGBD_01047	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KNIHOGBD_01048	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNIHOGBD_01049	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNIHOGBD_01050	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
KNIHOGBD_01051	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
KNIHOGBD_01052	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
KNIHOGBD_01053	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
KNIHOGBD_01054	4.87e-262	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
KNIHOGBD_01055	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNIHOGBD_01056	6.47e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KNIHOGBD_01057	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
KNIHOGBD_01058	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KNIHOGBD_01059	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KNIHOGBD_01060	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KNIHOGBD_01061	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01062	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KNIHOGBD_01063	6.84e-243	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
KNIHOGBD_01064	1.12e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KNIHOGBD_01065	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KNIHOGBD_01066	4.21e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KNIHOGBD_01067	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KNIHOGBD_01068	1.99e-43	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KNIHOGBD_01069	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KNIHOGBD_01070	3.61e-60	-	-	-	-	-	-	-	-
KNIHOGBD_01071	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNIHOGBD_01073	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
KNIHOGBD_01074	6.55e-97	-	-	-	-	-	-	-	-
KNIHOGBD_01075	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KNIHOGBD_01076	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KNIHOGBD_01077	2.31e-277	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
KNIHOGBD_01078	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
KNIHOGBD_01079	3.41e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KNIHOGBD_01080	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNIHOGBD_01081	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KNIHOGBD_01082	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
KNIHOGBD_01083	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KNIHOGBD_01084	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KNIHOGBD_01085	5.18e-109	-	-	-	-	-	-	-	-
KNIHOGBD_01086	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KNIHOGBD_01087	3.8e-213	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
KNIHOGBD_01089	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01090	0.000868	-	-	-	-	-	-	-	-
KNIHOGBD_01091	2.04e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KNIHOGBD_01092	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KNIHOGBD_01093	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KNIHOGBD_01094	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KNIHOGBD_01095	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KNIHOGBD_01096	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KNIHOGBD_01097	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KNIHOGBD_01098	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
KNIHOGBD_01099	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KNIHOGBD_01100	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
KNIHOGBD_01101	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KNIHOGBD_01102	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01103	3.41e-88	-	-	-	-	-	-	-	-
KNIHOGBD_01104	2.52e-32	-	-	-	-	-	-	-	-
KNIHOGBD_01105	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
KNIHOGBD_01106	4.74e-107	-	-	-	-	-	-	-	-
KNIHOGBD_01107	7.87e-30	-	-	-	-	-	-	-	-
KNIHOGBD_01110	5.02e-180	blpT	-	-	-	-	-	-	-
KNIHOGBD_01111	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
KNIHOGBD_01112	1.85e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNIHOGBD_01116	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01117	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_01118	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KNIHOGBD_01119	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KNIHOGBD_01120	2.85e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KNIHOGBD_01121	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KNIHOGBD_01122	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KNIHOGBD_01123	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KNIHOGBD_01124	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
KNIHOGBD_01125	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
KNIHOGBD_01126	2.09e-105	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KNIHOGBD_01127	3.74e-125	-	-	-	-	-	-	-	-
KNIHOGBD_01128	1.94e-96	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KNIHOGBD_01129	1.82e-05	-	-	-	-	-	-	-	-
KNIHOGBD_01130	1.38e-225	-	-	-	M	-	-	-	Rib/alpha-like repeat
KNIHOGBD_01131	4.21e-148	-	-	-	M	-	-	-	Rib/alpha-like repeat
KNIHOGBD_01132	1.89e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KNIHOGBD_01134	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KNIHOGBD_01135	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
KNIHOGBD_01136	9.63e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KNIHOGBD_01137	8.34e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KNIHOGBD_01138	2.07e-196	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
KNIHOGBD_01139	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KNIHOGBD_01140	1.69e-61	-	-	-	F	-	-	-	AAA domain
KNIHOGBD_01141	4.61e-104	-	-	-	K	-	-	-	acetyltransferase
KNIHOGBD_01142	6.58e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNIHOGBD_01143	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KNIHOGBD_01144	2.45e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KNIHOGBD_01145	1.44e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KNIHOGBD_01146	8.49e-85	-	-	-	E	-	-	-	amino acid
KNIHOGBD_01147	6.08e-161	yagE	-	-	E	-	-	-	Amino acid permease
KNIHOGBD_01148	9.58e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
KNIHOGBD_01149	8.13e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIHOGBD_01150	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KNIHOGBD_01151	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
KNIHOGBD_01152	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KNIHOGBD_01153	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KNIHOGBD_01154	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
KNIHOGBD_01155	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KNIHOGBD_01156	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KNIHOGBD_01157	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNIHOGBD_01158	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNIHOGBD_01159	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KNIHOGBD_01160	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNIHOGBD_01161	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNIHOGBD_01162	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
KNIHOGBD_01163	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KNIHOGBD_01164	8.06e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KNIHOGBD_01165	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KNIHOGBD_01166	9.11e-110	-	-	-	C	-	-	-	Aldo keto reductase
KNIHOGBD_01167	9.44e-63	-	-	-	M	-	-	-	LysM domain protein
KNIHOGBD_01168	1.8e-36	-	-	-	M	-	-	-	LysM domain protein
KNIHOGBD_01169	3.16e-179	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KNIHOGBD_01170	7.8e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
KNIHOGBD_01171	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KNIHOGBD_01172	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KNIHOGBD_01173	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KNIHOGBD_01174	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KNIHOGBD_01175	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
KNIHOGBD_01176	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KNIHOGBD_01177	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KNIHOGBD_01178	0.0	oatA	-	-	I	-	-	-	Acyltransferase
KNIHOGBD_01179	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNIHOGBD_01180	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KNIHOGBD_01181	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
KNIHOGBD_01182	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
KNIHOGBD_01183	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIHOGBD_01184	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
KNIHOGBD_01185	6.32e-41	-	-	-	S	-	-	-	reductase
KNIHOGBD_01186	2.98e-50	-	-	-	S	-	-	-	reductase
KNIHOGBD_01187	1.19e-43	-	-	-	S	-	-	-	reductase
KNIHOGBD_01188	4.66e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNIHOGBD_01189	2.37e-169	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01191	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNIHOGBD_01192	4.19e-92	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KNIHOGBD_01196	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
KNIHOGBD_01197	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KNIHOGBD_01198	1.87e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNIHOGBD_01199	1.06e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KNIHOGBD_01200	5.12e-174	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIHOGBD_01201	2.24e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIHOGBD_01202	1.02e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIHOGBD_01203	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KNIHOGBD_01204	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIHOGBD_01205	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNIHOGBD_01206	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNIHOGBD_01207	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KNIHOGBD_01208	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNIHOGBD_01209	1.51e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNIHOGBD_01210	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNIHOGBD_01211	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KNIHOGBD_01212	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KNIHOGBD_01213	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNIHOGBD_01214	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNIHOGBD_01215	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNIHOGBD_01216	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNIHOGBD_01217	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNIHOGBD_01218	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNIHOGBD_01219	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNIHOGBD_01220	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNIHOGBD_01221	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNIHOGBD_01222	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KNIHOGBD_01223	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNIHOGBD_01224	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNIHOGBD_01225	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNIHOGBD_01226	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNIHOGBD_01227	3.3e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNIHOGBD_01228	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KNIHOGBD_01229	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KNIHOGBD_01230	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNIHOGBD_01231	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KNIHOGBD_01232	6.44e-213	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KNIHOGBD_01233	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
KNIHOGBD_01234	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
KNIHOGBD_01235	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNIHOGBD_01236	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
KNIHOGBD_01237	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KNIHOGBD_01238	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KNIHOGBD_01239	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
KNIHOGBD_01240	1.91e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
KNIHOGBD_01241	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KNIHOGBD_01242	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
KNIHOGBD_01243	2.12e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KNIHOGBD_01244	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KNIHOGBD_01245	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KNIHOGBD_01246	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KNIHOGBD_01247	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KNIHOGBD_01249	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01250	1.2e-220	-	-	-	-	-	-	-	-
KNIHOGBD_01251	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNIHOGBD_01252	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KNIHOGBD_01253	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KNIHOGBD_01254	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNIHOGBD_01255	7.03e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KNIHOGBD_01256	4.39e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KNIHOGBD_01257	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNIHOGBD_01258	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNIHOGBD_01259	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNIHOGBD_01260	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
KNIHOGBD_01261	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
KNIHOGBD_01262	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KNIHOGBD_01263	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KNIHOGBD_01264	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNIHOGBD_01265	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNIHOGBD_01266	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KNIHOGBD_01267	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KNIHOGBD_01268	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNIHOGBD_01269	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KNIHOGBD_01270	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KNIHOGBD_01271	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNIHOGBD_01272	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KNIHOGBD_01273	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
KNIHOGBD_01274	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KNIHOGBD_01275	8.61e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KNIHOGBD_01276	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KNIHOGBD_01277	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KNIHOGBD_01278	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KNIHOGBD_01279	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
KNIHOGBD_01280	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
KNIHOGBD_01281	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNIHOGBD_01282	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KNIHOGBD_01283	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
KNIHOGBD_01284	4.96e-270	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01285	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KNIHOGBD_01286	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KNIHOGBD_01287	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNIHOGBD_01288	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KNIHOGBD_01289	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNIHOGBD_01290	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KNIHOGBD_01291	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
KNIHOGBD_01292	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KNIHOGBD_01293	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01294	2.1e-31	-	-	-	-	-	-	-	-
KNIHOGBD_01295	1.69e-06	-	-	-	-	-	-	-	-
KNIHOGBD_01296	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KNIHOGBD_01297	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KNIHOGBD_01298	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KNIHOGBD_01299	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNIHOGBD_01300	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01301	1.22e-192	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
KNIHOGBD_01302	1.35e-47	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01303	2.16e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNIHOGBD_01304	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KNIHOGBD_01305	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNIHOGBD_01306	1.31e-194	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNIHOGBD_01307	5.81e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KNIHOGBD_01308	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
KNIHOGBD_01309	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
KNIHOGBD_01310	2.51e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNIHOGBD_01311	1.59e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
KNIHOGBD_01312	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KNIHOGBD_01313	8.01e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KNIHOGBD_01314	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KNIHOGBD_01315	3.52e-163	csrR	-	-	K	-	-	-	response regulator
KNIHOGBD_01316	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KNIHOGBD_01317	2.19e-18	-	-	-	-	-	-	-	-
KNIHOGBD_01318	6.5e-122	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KNIHOGBD_01319	2.95e-283	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01320	1.13e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
KNIHOGBD_01321	8.13e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNIHOGBD_01322	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KNIHOGBD_01323	5.59e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNIHOGBD_01324	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KNIHOGBD_01326	2.9e-31	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
KNIHOGBD_01328	3.74e-180	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KNIHOGBD_01329	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
KNIHOGBD_01330	0.0	fusA1	-	-	J	-	-	-	elongation factor G
KNIHOGBD_01331	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
KNIHOGBD_01332	1.7e-200	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KNIHOGBD_01333	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KNIHOGBD_01334	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KNIHOGBD_01335	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KNIHOGBD_01336	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01337	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KNIHOGBD_01338	2.55e-26	-	-	-	-	-	-	-	-
KNIHOGBD_01339	3.93e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KNIHOGBD_01340	8.87e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
KNIHOGBD_01341	4.65e-120	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01342	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01343	1.09e-148	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KNIHOGBD_01344	5.76e-66	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KNIHOGBD_01345	3.47e-19	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
KNIHOGBD_01346	3.75e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNIHOGBD_01347	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
KNIHOGBD_01348	8.08e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KNIHOGBD_01349	2.23e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
KNIHOGBD_01350	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
KNIHOGBD_01351	2.45e-164	-	-	-	-	-	-	-	-
KNIHOGBD_01352	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KNIHOGBD_01353	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KNIHOGBD_01354	1.01e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01355	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KNIHOGBD_01356	1.11e-177	-	-	-	-	-	-	-	-
KNIHOGBD_01357	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KNIHOGBD_01358	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNIHOGBD_01359	2.32e-47	-	-	-	-	-	-	-	-
KNIHOGBD_01360	1.88e-157	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
KNIHOGBD_01361	4.04e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
KNIHOGBD_01362	5.84e-312	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
KNIHOGBD_01363	7.95e-292	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
KNIHOGBD_01364	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
KNIHOGBD_01365	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KNIHOGBD_01366	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
KNIHOGBD_01367	1.8e-34	-	-	-	-	-	-	-	-
KNIHOGBD_01368	2.24e-202	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KNIHOGBD_01369	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
KNIHOGBD_01370	7.84e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNIHOGBD_01371	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNIHOGBD_01372	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNIHOGBD_01373	2.82e-201	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01374	7.91e-164	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01375	1.68e-149	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
KNIHOGBD_01376	1.11e-98	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
KNIHOGBD_01377	4.55e-79	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
KNIHOGBD_01378	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
KNIHOGBD_01379	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
KNIHOGBD_01380	2.44e-210	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
KNIHOGBD_01381	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNIHOGBD_01382	4.61e-180	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
KNIHOGBD_01383	2.22e-98	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KNIHOGBD_01384	4.06e-277	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KNIHOGBD_01385	6.03e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KNIHOGBD_01386	3.77e-260	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KNIHOGBD_01387	4.09e-127	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KNIHOGBD_01388	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
KNIHOGBD_01389	4.16e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNIHOGBD_01390	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KNIHOGBD_01391	3.94e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KNIHOGBD_01393	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KNIHOGBD_01394	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
KNIHOGBD_01395	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KNIHOGBD_01397	0.0	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01398	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
KNIHOGBD_01399	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
KNIHOGBD_01400	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
KNIHOGBD_01401	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KNIHOGBD_01402	2.57e-61	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
KNIHOGBD_01403	2.64e-49	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
KNIHOGBD_01404	4.37e-78	-	-	-	S	-	-	-	SIR2-like domain
KNIHOGBD_01406	1.15e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
KNIHOGBD_01407	2.06e-88	-	-	-	-	-	-	-	-
KNIHOGBD_01408	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
KNIHOGBD_01409	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KNIHOGBD_01410	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KNIHOGBD_01411	2.28e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KNIHOGBD_01412	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNIHOGBD_01413	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KNIHOGBD_01414	1.61e-70	-	-	-	-	-	-	-	-
KNIHOGBD_01416	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
KNIHOGBD_01417	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KNIHOGBD_01418	3.39e-88	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
KNIHOGBD_01420	3.11e-13	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KNIHOGBD_01421	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
KNIHOGBD_01422	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
KNIHOGBD_01423	3.92e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
KNIHOGBD_01424	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
KNIHOGBD_01425	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
KNIHOGBD_01426	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
KNIHOGBD_01427	1.2e-191	-	-	-	I	-	-	-	Acyl-transferase
KNIHOGBD_01429	1.09e-46	-	-	-	-	-	-	-	-
KNIHOGBD_01431	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KNIHOGBD_01432	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KNIHOGBD_01433	0.0	yycH	-	-	S	-	-	-	YycH protein
KNIHOGBD_01434	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
KNIHOGBD_01435	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
KNIHOGBD_01436	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
KNIHOGBD_01437	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KNIHOGBD_01438	9.45e-180	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01440	2.09e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNIHOGBD_01441	7.32e-232	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
KNIHOGBD_01442	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
KNIHOGBD_01443	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KNIHOGBD_01444	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KNIHOGBD_01445	1.98e-168	-	-	-	-	-	-	-	-
KNIHOGBD_01446	1.72e-149	-	-	-	-	-	-	-	-
KNIHOGBD_01447	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNIHOGBD_01448	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
KNIHOGBD_01449	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KNIHOGBD_01450	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KNIHOGBD_01451	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
KNIHOGBD_01452	1.11e-131	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01453	1.77e-83	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
KNIHOGBD_01454	4.63e-32	-	-	-	-	-	-	-	-
KNIHOGBD_01455	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
KNIHOGBD_01456	8.28e-102	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
KNIHOGBD_01457	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
KNIHOGBD_01458	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KNIHOGBD_01459	1.97e-294	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KNIHOGBD_01460	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KNIHOGBD_01461	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
KNIHOGBD_01462	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
KNIHOGBD_01463	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KNIHOGBD_01464	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
KNIHOGBD_01465	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KNIHOGBD_01466	1.01e-22	-	-	-	L	-	-	-	Transposase
KNIHOGBD_01467	7.51e-16	-	-	-	L	-	-	-	Transposase
KNIHOGBD_01468	1.21e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01470	1.77e-60	-	-	-	K	-	-	-	LytTr DNA-binding domain
KNIHOGBD_01471	1.47e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KNIHOGBD_01472	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KNIHOGBD_01473	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNIHOGBD_01474	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNIHOGBD_01475	3.52e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KNIHOGBD_01476	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNIHOGBD_01477	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
KNIHOGBD_01478	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KNIHOGBD_01479	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
KNIHOGBD_01480	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
KNIHOGBD_01481	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KNIHOGBD_01482	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
KNIHOGBD_01483	8.53e-59	-	-	-	-	-	-	-	-
KNIHOGBD_01484	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
KNIHOGBD_01485	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KNIHOGBD_01486	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
KNIHOGBD_01487	2.91e-67	-	-	-	-	-	-	-	-
KNIHOGBD_01488	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNIHOGBD_01489	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KNIHOGBD_01490	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KNIHOGBD_01491	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
KNIHOGBD_01492	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
KNIHOGBD_01493	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KNIHOGBD_01494	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
KNIHOGBD_01495	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
KNIHOGBD_01496	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KNIHOGBD_01497	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KNIHOGBD_01498	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KNIHOGBD_01499	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
KNIHOGBD_01500	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KNIHOGBD_01501	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNIHOGBD_01502	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNIHOGBD_01503	3.88e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNIHOGBD_01504	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KNIHOGBD_01505	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNIHOGBD_01506	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNIHOGBD_01507	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KNIHOGBD_01508	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KNIHOGBD_01509	4.01e-192	ylmH	-	-	S	-	-	-	S4 domain protein
KNIHOGBD_01510	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
KNIHOGBD_01511	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNIHOGBD_01512	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KNIHOGBD_01513	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KNIHOGBD_01514	1.22e-55	-	-	-	-	-	-	-	-
KNIHOGBD_01515	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNIHOGBD_01516	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KNIHOGBD_01517	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KNIHOGBD_01518	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KNIHOGBD_01519	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
KNIHOGBD_01520	2.31e-148	-	-	-	S	-	-	-	repeat protein
KNIHOGBD_01521	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KNIHOGBD_01522	0.0	-	-	-	L	-	-	-	Nuclease-related domain
KNIHOGBD_01523	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KNIHOGBD_01524	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNIHOGBD_01525	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIHOGBD_01526	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIHOGBD_01527	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KNIHOGBD_01528	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNIHOGBD_01529	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KNIHOGBD_01530	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNIHOGBD_01531	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_01532	2.16e-79	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_01533	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KNIHOGBD_01534	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIHOGBD_01536	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KNIHOGBD_01537	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
KNIHOGBD_01538	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
KNIHOGBD_01539	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KNIHOGBD_01540	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
KNIHOGBD_01541	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KNIHOGBD_01542	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KNIHOGBD_01543	2.12e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
KNIHOGBD_01544	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
KNIHOGBD_01545	1.09e-58	-	-	-	L	-	-	-	Transposase
KNIHOGBD_01546	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNIHOGBD_01547	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KNIHOGBD_01548	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KNIHOGBD_01549	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KNIHOGBD_01550	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KNIHOGBD_01551	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
KNIHOGBD_01552	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KNIHOGBD_01553	0.0	-	-	-	E	-	-	-	amino acid
KNIHOGBD_01554	1.33e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNIHOGBD_01555	1.17e-56	-	-	-	-	-	-	-	-
KNIHOGBD_01556	8.68e-69	-	-	-	-	-	-	-	-
KNIHOGBD_01557	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
KNIHOGBD_01558	8.88e-178	-	-	-	P	-	-	-	Voltage gated chloride channel
KNIHOGBD_01559	9.64e-219	-	-	-	-	-	-	-	-
KNIHOGBD_01560	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KNIHOGBD_01561	1.74e-282	ynbB	-	-	P	-	-	-	aluminum resistance
KNIHOGBD_01562	1.9e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNIHOGBD_01563	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
KNIHOGBD_01564	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
KNIHOGBD_01565	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
KNIHOGBD_01566	1.94e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNIHOGBD_01567	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KNIHOGBD_01568	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KNIHOGBD_01569	0.0	-	-	-	S	-	-	-	membrane
KNIHOGBD_01570	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
KNIHOGBD_01571	3.87e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KNIHOGBD_01572	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
KNIHOGBD_01573	1.32e-171	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KNIHOGBD_01574	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KNIHOGBD_01575	1.73e-79	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
KNIHOGBD_01576	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_01577	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KNIHOGBD_01578	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KNIHOGBD_01579	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
KNIHOGBD_01580	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KNIHOGBD_01581	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KNIHOGBD_01582	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KNIHOGBD_01583	2.37e-242	-	-	-	T	-	-	-	GHKL domain
KNIHOGBD_01584	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
KNIHOGBD_01585	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KNIHOGBD_01586	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
KNIHOGBD_01589	1.71e-156	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KNIHOGBD_01590	7.98e-35	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KNIHOGBD_01591	4.68e-25	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KNIHOGBD_01592	8.24e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KNIHOGBD_01593	7.62e-32	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KNIHOGBD_01595	1.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01596	5.85e-67	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01598	1.54e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
KNIHOGBD_01599	2.78e-45	-	-	-	-	-	-	-	-
KNIHOGBD_01601	7.63e-28	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KNIHOGBD_01603	2.62e-155	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KNIHOGBD_01605	2.12e-86	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01606	2.24e-36	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KNIHOGBD_01607	0.0	snf	-	-	KL	-	-	-	domain protein
KNIHOGBD_01608	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KNIHOGBD_01609	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNIHOGBD_01610	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNIHOGBD_01611	1.91e-194	-	-	-	K	-	-	-	Transcriptional regulator
KNIHOGBD_01612	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KNIHOGBD_01613	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNIHOGBD_01614	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
KNIHOGBD_01615	2.15e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KNIHOGBD_01616	7.64e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNIHOGBD_01617	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNIHOGBD_01618	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
KNIHOGBD_01619	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KNIHOGBD_01620	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
KNIHOGBD_01621	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
KNIHOGBD_01622	0.0	-	-	-	E	-	-	-	Amino acid permease
KNIHOGBD_01623	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
KNIHOGBD_01624	4.97e-311	ynbB	-	-	P	-	-	-	aluminum resistance
KNIHOGBD_01625	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KNIHOGBD_01626	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KNIHOGBD_01627	6.74e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KNIHOGBD_01628	7.62e-223	-	-	-	-	-	-	-	-
KNIHOGBD_01629	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
KNIHOGBD_01630	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KNIHOGBD_01631	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KNIHOGBD_01632	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KNIHOGBD_01633	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
KNIHOGBD_01634	1.05e-119	-	-	-	S	-	-	-	membrane
KNIHOGBD_01635	2.61e-23	-	-	-	-	-	-	-	-
KNIHOGBD_01636	2.94e-250	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KNIHOGBD_01637	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
KNIHOGBD_01638	1.03e-104	-	-	-	-	-	-	-	-
KNIHOGBD_01639	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KNIHOGBD_01640	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KNIHOGBD_01641	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KNIHOGBD_01642	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KNIHOGBD_01643	0.0	ycaM	-	-	E	-	-	-	amino acid
KNIHOGBD_01644	0.0	-	-	-	-	-	-	-	-
KNIHOGBD_01646	9.26e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
KNIHOGBD_01647	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNIHOGBD_01648	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KNIHOGBD_01649	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNIHOGBD_01650	2.6e-37	-	-	-	-	-	-	-	-
KNIHOGBD_01651	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
KNIHOGBD_01652	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNIHOGBD_01653	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KNIHOGBD_01654	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KNIHOGBD_01655	2.63e-205	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KNIHOGBD_01656	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
KNIHOGBD_01657	2.44e-143	-	-	-	S	-	-	-	CYTH
KNIHOGBD_01658	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KNIHOGBD_01659	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNIHOGBD_01660	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KNIHOGBD_01661	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KNIHOGBD_01662	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
KNIHOGBD_01663	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KNIHOGBD_01664	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KNIHOGBD_01665	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
KNIHOGBD_01666	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KNIHOGBD_01667	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
KNIHOGBD_01668	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KNIHOGBD_01669	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
KNIHOGBD_01670	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
KNIHOGBD_01671	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KNIHOGBD_01672	2.13e-152	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
KNIHOGBD_01673	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNIHOGBD_01674	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNIHOGBD_01675	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KNIHOGBD_01676	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KNIHOGBD_01677	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KNIHOGBD_01678	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
KNIHOGBD_01679	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KNIHOGBD_01680	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNIHOGBD_01681	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNIHOGBD_01682	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNIHOGBD_01683	8.33e-27	-	-	-	-	-	-	-	-
KNIHOGBD_01684	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNIHOGBD_01685	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNIHOGBD_01686	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KNIHOGBD_01687	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KNIHOGBD_01688	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KNIHOGBD_01689	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNIHOGBD_01690	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KNIHOGBD_01691	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KNIHOGBD_01692	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KNIHOGBD_01693	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KNIHOGBD_01694	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KNIHOGBD_01695	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNIHOGBD_01696	0.0	-	-	-	S	-	-	-	SH3-like domain
KNIHOGBD_01697	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_01698	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KNIHOGBD_01699	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KNIHOGBD_01700	6.9e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KNIHOGBD_01701	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
KNIHOGBD_01702	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KNIHOGBD_01703	2.46e-118	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
KNIHOGBD_01704	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KNIHOGBD_01705	9.89e-74	-	-	-	-	-	-	-	-
KNIHOGBD_01706	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KNIHOGBD_01707	5.03e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KNIHOGBD_01708	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KNIHOGBD_01709	3.09e-71	-	-	-	-	-	-	-	-
KNIHOGBD_01710	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KNIHOGBD_01711	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KNIHOGBD_01712	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNIHOGBD_01713	0.0	potE	-	-	E	-	-	-	Amino Acid
KNIHOGBD_01714	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
KNIHOGBD_01715	0.0	-	-	-	-	-	-	-	-
KNIHOGBD_01716	5.87e-110	-	-	-	-	-	-	-	-
KNIHOGBD_01717	1.92e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
KNIHOGBD_01718	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
KNIHOGBD_01719	1.36e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KNIHOGBD_01720	2.27e-132	sptS	-	-	T	-	-	-	Histidine kinase
KNIHOGBD_01721	2.05e-146	sptS	-	-	T	-	-	-	Histidine kinase
KNIHOGBD_01722	1.52e-135	dltr	-	-	K	-	-	-	response regulator
KNIHOGBD_01723	1.19e-128	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
KNIHOGBD_01724	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
KNIHOGBD_01725	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KNIHOGBD_01726	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
KNIHOGBD_01727	2.06e-298	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
KNIHOGBD_01728	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KNIHOGBD_01729	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
KNIHOGBD_01730	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KNIHOGBD_01731	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
KNIHOGBD_01732	4.04e-29	-	-	-	-	-	-	-	-
KNIHOGBD_01733	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
KNIHOGBD_01734	1.13e-126	-	-	-	-	-	-	-	-
KNIHOGBD_01735	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
KNIHOGBD_01736	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KNIHOGBD_01737	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
KNIHOGBD_01738	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNIHOGBD_01739	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
KNIHOGBD_01740	7.76e-98	-	-	-	-	-	-	-	-
KNIHOGBD_01741	1.74e-111	-	-	-	-	-	-	-	-
KNIHOGBD_01742	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KNIHOGBD_01743	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNIHOGBD_01744	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KNIHOGBD_01745	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KNIHOGBD_01746	7.74e-61	-	-	-	-	-	-	-	-
KNIHOGBD_01747	2e-149	-	-	-	S	-	-	-	Peptidase family M23
KNIHOGBD_01748	1.22e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNIHOGBD_01750	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIHOGBD_01751	5.47e-151	-	-	-	-	-	-	-	-
KNIHOGBD_01752	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KNIHOGBD_01753	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KNIHOGBD_01754	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KNIHOGBD_01755	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KNIHOGBD_01756	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
KNIHOGBD_01757	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_01758	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KNIHOGBD_01759	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIHOGBD_01760	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KNIHOGBD_01762	9.39e-71	-	-	-	-	-	-	-	-
KNIHOGBD_01763	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNIHOGBD_01764	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
KNIHOGBD_01765	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
KNIHOGBD_01766	5.05e-11	-	-	-	-	-	-	-	-
KNIHOGBD_01767	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
KNIHOGBD_01768	2.18e-122	yneE	-	-	K	-	-	-	Transcriptional regulator
KNIHOGBD_01769	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
KNIHOGBD_01770	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_01771	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KNIHOGBD_01772	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KNIHOGBD_01773	1.58e-282	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
KNIHOGBD_01774	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
KNIHOGBD_01775	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
KNIHOGBD_01776	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNIHOGBD_01777	5.38e-39	-	-	-	-	-	-	-	-
KNIHOGBD_01778	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KNIHOGBD_01779	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KNIHOGBD_01780	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNIHOGBD_01781	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNIHOGBD_01782	2.65e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KNIHOGBD_01783	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
KNIHOGBD_01784	1.97e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
KNIHOGBD_01785	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KNIHOGBD_01786	5.61e-156	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KNIHOGBD_01787	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
KNIHOGBD_01788	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
KNIHOGBD_01789	1.48e-166	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KNIHOGBD_01790	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNIHOGBD_01791	2.82e-84	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
KNIHOGBD_01792	1.48e-28	axe1	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	acetyl xylan esterase
KNIHOGBD_01793	1.19e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KNIHOGBD_01794	1.1e-155	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNIHOGBD_01795	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
KNIHOGBD_01796	1.51e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
KNIHOGBD_01797	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KNIHOGBD_01798	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KNIHOGBD_01799	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
KNIHOGBD_01800	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KNIHOGBD_01801	3.2e-95	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KNIHOGBD_01802	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KNIHOGBD_01803	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KNIHOGBD_01804	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNIHOGBD_01805	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KNIHOGBD_01806	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
KNIHOGBD_01807	9.67e-104	-	-	-	-	-	-	-	-
KNIHOGBD_01808	1.93e-308	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KNIHOGBD_01809	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KNIHOGBD_01810	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KNIHOGBD_01811	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KNIHOGBD_01812	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KNIHOGBD_01813	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
KNIHOGBD_01814	5.5e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNIHOGBD_01815	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
KNIHOGBD_01816	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KNIHOGBD_01817	9.62e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
KNIHOGBD_01818	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KNIHOGBD_01819	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KNIHOGBD_01820	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KNIHOGBD_01821	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
KNIHOGBD_01822	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KNIHOGBD_01823	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
KNIHOGBD_01824	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KNIHOGBD_01825	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
KNIHOGBD_01826	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KNIHOGBD_01827	4.4e-215	-	-	-	-	-	-	-	-
KNIHOGBD_01828	4.01e-184	-	-	-	-	-	-	-	-
KNIHOGBD_01829	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KNIHOGBD_01830	3.49e-36	-	-	-	-	-	-	-	-
KNIHOGBD_01831	3.85e-193	-	-	-	-	-	-	-	-
KNIHOGBD_01832	2.22e-154	-	-	-	-	-	-	-	-
KNIHOGBD_01833	1.65e-180	-	-	-	-	-	-	-	-
KNIHOGBD_01834	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KNIHOGBD_01835	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
KNIHOGBD_01836	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KNIHOGBD_01837	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNIHOGBD_01838	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KNIHOGBD_01839	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KNIHOGBD_01840	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
KNIHOGBD_01841	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNIHOGBD_01842	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KNIHOGBD_01843	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KNIHOGBD_01844	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KNIHOGBD_01845	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KNIHOGBD_01846	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNIHOGBD_01847	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNIHOGBD_01848	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KNIHOGBD_01849	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
KNIHOGBD_01850	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KNIHOGBD_01851	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KNIHOGBD_01852	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
KNIHOGBD_01858	5.74e-285	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
KNIHOGBD_01859	3.68e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KNIHOGBD_01860	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNIHOGBD_01861	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNIHOGBD_01862	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KNIHOGBD_01863	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNIHOGBD_01864	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KNIHOGBD_01865	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KNIHOGBD_01866	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
KNIHOGBD_01867	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01868	2.35e-58	-	-	-	-	-	-	-	-
KNIHOGBD_01869	1.06e-133	-	-	-	S	-	-	-	Bacteriocin helveticin-J
KNIHOGBD_01870	1.14e-154	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01871	6.57e-175	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01872	6.49e-268	-	-	-	-	-	-	-	-
KNIHOGBD_01873	6.46e-27	-	-	-	-	-	-	-	-
KNIHOGBD_01874	2.71e-222	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
KNIHOGBD_01881	2.72e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
KNIHOGBD_01884	2.13e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
KNIHOGBD_01887	1.11e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
KNIHOGBD_01888	1.11e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KNIHOGBD_01891	3.07e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
KNIHOGBD_01892	2.19e-46	-	-	-	K	-	-	-	Helix-turn-helix domain
KNIHOGBD_01894	2.95e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01896	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KNIHOGBD_01898	2.23e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KNIHOGBD_01900	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
KNIHOGBD_01902	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01903	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
KNIHOGBD_01905	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
KNIHOGBD_01906	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KNIHOGBD_01907	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNIHOGBD_01908	1.59e-213	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNIHOGBD_01909	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNIHOGBD_01910	2.75e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KNIHOGBD_01911	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
KNIHOGBD_01912	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KNIHOGBD_01913	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KNIHOGBD_01914	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KNIHOGBD_01915	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KNIHOGBD_01916	2.14e-231	-	-	-	M	-	-	-	CHAP domain
KNIHOGBD_01917	2.79e-102	-	-	-	-	-	-	-	-
KNIHOGBD_01918	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNIHOGBD_01919	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNIHOGBD_01920	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
KNIHOGBD_01921	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KNIHOGBD_01922	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KNIHOGBD_01923	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNIHOGBD_01924	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KNIHOGBD_01926	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
KNIHOGBD_01927	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
KNIHOGBD_01928	1.38e-154	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01930	2.85e-54	-	-	-	-	-	-	-	-
KNIHOGBD_01931	3.6e-101	-	-	-	K	-	-	-	DNA-templated transcription, initiation
KNIHOGBD_01933	1.03e-188	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
KNIHOGBD_01934	6.87e-27	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
KNIHOGBD_01935	1.2e-89	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_01936	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KNIHOGBD_01937	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KNIHOGBD_01938	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KNIHOGBD_01939	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KNIHOGBD_01940	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNIHOGBD_01941	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KNIHOGBD_01942	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
KNIHOGBD_01943	1.77e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KNIHOGBD_01944	6.76e-80	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KNIHOGBD_01945	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNIHOGBD_01946	1.23e-125	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KNIHOGBD_01947	4.33e-95	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KNIHOGBD_01948	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNIHOGBD_01949	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KNIHOGBD_01950	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KNIHOGBD_01951	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KNIHOGBD_01952	1.13e-41	-	-	-	M	-	-	-	Lysin motif
KNIHOGBD_01953	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNIHOGBD_01954	1.09e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KNIHOGBD_01960	7e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KNIHOGBD_01961	1.21e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_01962	1.71e-102	-	-	-	S	-	-	-	DNA binding
KNIHOGBD_01967	8.72e-07	-	-	-	-	-	-	-	-
KNIHOGBD_01968	5.23e-122	-	-	-	S	-	-	-	AntA/AntB antirepressor
KNIHOGBD_01974	2.36e-08	-	-	-	K	-	-	-	DNA-binding protein
KNIHOGBD_01978	1.11e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
KNIHOGBD_01979	3.2e-41	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
KNIHOGBD_01980	9.24e-64	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
KNIHOGBD_01986	5.99e-52	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
KNIHOGBD_01987	1.08e-10	-	-	-	-	-	-	-	-
KNIHOGBD_01996	8.27e-46	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
KNIHOGBD_01997	7.69e-16	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
KNIHOGBD_01998	3.14e-48	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
KNIHOGBD_01999	1.22e-24	-	-	-	S	-	-	-	Terminase-like family
KNIHOGBD_02000	1.1e-235	-	-	-	S	-	-	-	Terminase-like family
KNIHOGBD_02001	2.28e-178	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
KNIHOGBD_02002	5.89e-127	-	-	-	S	-	-	-	Phage Mu protein F like protein
KNIHOGBD_02003	1.14e-16	-	-	-	S	-	-	-	Lysin motif
KNIHOGBD_02004	2.77e-137	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
KNIHOGBD_02005	5.09e-76	-	-	-	-	-	-	-	-
KNIHOGBD_02006	1.83e-181	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2184)
KNIHOGBD_02008	2.18e-96	-	-	-	-	-	-	-	-
KNIHOGBD_02009	1.8e-59	-	-	-	-	-	-	-	-
KNIHOGBD_02010	7.95e-69	-	-	-	-	-	-	-	-
KNIHOGBD_02011	1.75e-190	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
KNIHOGBD_02012	1.1e-72	-	-	-	-	-	-	-	-
KNIHOGBD_02015	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
KNIHOGBD_02016	1.19e-68	-	-	-	M	-	-	-	LysM domain
KNIHOGBD_02017	6.91e-61	-	-	-	-	-	-	-	-
KNIHOGBD_02018	1.57e-128	-	-	-	-	-	-	-	-
KNIHOGBD_02019	4.6e-63	-	-	-	-	-	-	-	-
KNIHOGBD_02020	2.37e-43	-	-	-	-	-	-	-	-
KNIHOGBD_02021	3.71e-154	-	-	-	S	-	-	-	Baseplate J-like protein
KNIHOGBD_02023	8.2e-07	-	-	-	-	-	-	-	-
KNIHOGBD_02029	1.28e-54	-	-	-	-	-	-	-	-
KNIHOGBD_02030	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
KNIHOGBD_02033	6.31e-27	-	-	-	-	-	-	-	-
KNIHOGBD_02034	1.76e-38	-	-	-	-	-	-	-	-
KNIHOGBD_02035	5.31e-221	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KNIHOGBD_02036	5.3e-32	-	-	-	-	-	-	-	-
KNIHOGBD_02037	9.71e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNIHOGBD_02038	1.03e-65	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
KNIHOGBD_02039	7.41e-136	-	-	-	-	-	-	-	-
KNIHOGBD_02040	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
KNIHOGBD_02041	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KNIHOGBD_02042	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
KNIHOGBD_02043	2.52e-76	-	-	-	S	-	-	-	Cupredoxin-like domain
KNIHOGBD_02044	2.23e-48	-	-	-	-	-	-	-	-
KNIHOGBD_02048	2.27e-179	-	-	-	-	-	-	-	-
KNIHOGBD_02050	4.93e-34	-	-	-	L	-	-	-	four-way junction helicase activity
KNIHOGBD_02051	5.53e-20	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
KNIHOGBD_02052	1.11e-143	-	-	-	S	-	-	-	Fic/DOC family
KNIHOGBD_02053	7.42e-55	-	-	-	E	-	-	-	Pfam:DUF955
KNIHOGBD_02054	8.4e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
KNIHOGBD_02055	1.33e-22	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNIHOGBD_02057	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KNIHOGBD_02058	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNIHOGBD_02059	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNIHOGBD_02060	1.13e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNIHOGBD_02061	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
KNIHOGBD_02062	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
KNIHOGBD_02063	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KNIHOGBD_02064	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KNIHOGBD_02065	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KNIHOGBD_02066	1.64e-59	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KNIHOGBD_02067	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KNIHOGBD_02068	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KNIHOGBD_02069	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNIHOGBD_02070	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
KNIHOGBD_02071	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KNIHOGBD_02073	1.14e-115	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
KNIHOGBD_02074	7.6e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KNIHOGBD_02075	3.56e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KNIHOGBD_02076	3.92e-110	usp5	-	-	T	-	-	-	universal stress protein
KNIHOGBD_02078	1.78e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
KNIHOGBD_02079	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KNIHOGBD_02080	5.49e-168	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KNIHOGBD_02081	1.29e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KNIHOGBD_02082	7.05e-103	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
KNIHOGBD_02083	3.98e-97	-	-	-	M	-	-	-	LysM domain
KNIHOGBD_02084	3.3e-42	-	-	-	-	-	-	-	-
KNIHOGBD_02086	2.58e-45	-	-	-	-	-	-	-	-
KNIHOGBD_02087	7.84e-95	-	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_02088	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
KNIHOGBD_02089	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_02090	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
KNIHOGBD_02091	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIHOGBD_02092	2.53e-56	-	-	-	-	-	-	-	-
KNIHOGBD_02093	1.13e-218	-	-	-	GK	-	-	-	ROK family
KNIHOGBD_02094	3.49e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNIHOGBD_02095	0.0	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_02096	5.52e-113	-	-	-	-	-	-	-	-
KNIHOGBD_02097	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KNIHOGBD_02098	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
KNIHOGBD_02099	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KNIHOGBD_02100	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
KNIHOGBD_02101	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KNIHOGBD_02102	8.44e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
KNIHOGBD_02103	5.75e-152	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
KNIHOGBD_02104	5.29e-256	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNIHOGBD_02105	2.25e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KNIHOGBD_02106	2.74e-200	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KNIHOGBD_02107	1.15e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KNIHOGBD_02108	1.32e-114	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KNIHOGBD_02109	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
KNIHOGBD_02110	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNIHOGBD_02111	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
KNIHOGBD_02112	1.5e-90	-	-	-	-	-	-	-	-
KNIHOGBD_02113	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
KNIHOGBD_02114	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_02118	1.54e-07	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KNIHOGBD_02119	1.89e-20	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KNIHOGBD_02121	8.5e-10	-	-	-	M	-	-	-	oxidoreductase activity
KNIHOGBD_02122	3.24e-13	-	-	-	S	-	-	-	SLAP domain
KNIHOGBD_02127	5.3e-161	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
KNIHOGBD_02131	8.09e-195	-	-	-	S	-	-	-	COG0433 Predicted ATPase
KNIHOGBD_02132	2.23e-24	lysM	-	-	M	-	-	-	LysM domain
KNIHOGBD_02141	1.86e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
KNIHOGBD_02142	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
KNIHOGBD_02143	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
KNIHOGBD_02144	1.14e-164	-	-	-	S	-	-	-	Fic/DOC family
KNIHOGBD_02145	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
KNIHOGBD_02146	4.65e-184	-	-	-	D	-	-	-	AAA domain
KNIHOGBD_02147	1.17e-38	-	-	-	-	-	-	-	-
KNIHOGBD_02148	4.87e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KNIHOGBD_02149	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
KNIHOGBD_02150	1.07e-141	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
KNIHOGBD_02151	1.48e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNIHOGBD_02152	5.23e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
KNIHOGBD_02153	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNIHOGBD_02154	4.26e-22	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
KNIHOGBD_02155	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
KNIHOGBD_02156	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
KNIHOGBD_02157	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
KNIHOGBD_02158	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNIHOGBD_02159	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KNIHOGBD_02160	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNIHOGBD_02161	2.29e-112	-	-	-	-	-	-	-	-
KNIHOGBD_02162	3.03e-243	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
KNIHOGBD_02163	6.04e-49	-	-	-	-	-	-	-	-
KNIHOGBD_02165	3.44e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KNIHOGBD_02166	4.6e-113	-	-	-	K	-	-	-	GNAT family
KNIHOGBD_02167	4.31e-257	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
KNIHOGBD_02168	4.45e-156	rbtT	-	-	P	ko:K13021	-	ko00000,ko02000	Major Facilitator Superfamily
KNIHOGBD_02169	2.81e-76	-	-	-	EGP	-	-	-	Major Facilitator
KNIHOGBD_02170	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KNIHOGBD_02171	3.33e-70	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
KNIHOGBD_02172	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNIHOGBD_02173	4.28e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KNIHOGBD_02174	8.57e-199	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNIHOGBD_02175	1.45e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KNIHOGBD_02176	4e-152	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
KNIHOGBD_02178	6.09e-121	-	-	-	-	-	-	-	-
KNIHOGBD_02179	6.06e-54	yabO	-	-	J	-	-	-	S4 domain protein
KNIHOGBD_02180	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNIHOGBD_02181	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KNIHOGBD_02182	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KNIHOGBD_02183	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
KNIHOGBD_02184	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KNIHOGBD_02185	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KNIHOGBD_02186	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KNIHOGBD_02187	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KNIHOGBD_02188	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
KNIHOGBD_02189	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
KNIHOGBD_02190	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KNIHOGBD_02191	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KNIHOGBD_02192	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KNIHOGBD_02193	1.34e-162	-	-	-	-	-	-	-	-
KNIHOGBD_02194	1.18e-297	-	-	-	S	-	-	-	response to antibiotic
KNIHOGBD_02195	3.43e-79	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
KNIHOGBD_02196	1.53e-189	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
KNIHOGBD_02197	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
KNIHOGBD_02198	5.71e-230	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
KNIHOGBD_02199	1.39e-143	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KNIHOGBD_02200	1.73e-48	-	-	-	-	-	-	-	-
KNIHOGBD_02201	1.24e-08	-	-	-	-	-	-	-	-
KNIHOGBD_02202	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
KNIHOGBD_02203	1.51e-159	-	-	-	-	-	-	-	-
KNIHOGBD_02206	4.13e-83	-	-	-	-	-	-	-	-
KNIHOGBD_02207	3.56e-47	-	-	-	-	-	-	-	-
KNIHOGBD_02208	2.63e-50	-	-	-	-	-	-	-	-
KNIHOGBD_02209	1.25e-143	-	-	-	K	-	-	-	WHG domain
KNIHOGBD_02210	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KNIHOGBD_02211	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KNIHOGBD_02212	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KNIHOGBD_02213	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KNIHOGBD_02215	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
KNIHOGBD_02216	6.57e-45	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
KNIHOGBD_02217	1.49e-47	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KNIHOGBD_02219	7.56e-230	-	-	-	L	-	-	-	N-6 DNA Methylase
KNIHOGBD_02221	3.62e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNIHOGBD_02224	6.12e-94	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
KNIHOGBD_02225	3.07e-124	-	-	-	-	-	-	-	-
KNIHOGBD_02226	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KNIHOGBD_02227	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNIHOGBD_02228	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KNIHOGBD_02229	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
KNIHOGBD_02230	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KNIHOGBD_02231	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KNIHOGBD_02232	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KNIHOGBD_02233	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_02234	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KNIHOGBD_02235	9.91e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KNIHOGBD_02236	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNIHOGBD_02237	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
KNIHOGBD_02238	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNIHOGBD_02239	8.04e-190	-	-	-	S	-	-	-	hydrolase
KNIHOGBD_02240	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
KNIHOGBD_02241	2.85e-153	-	-	-	-	-	-	-	-
KNIHOGBD_02242	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNIHOGBD_02243	2.52e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KNIHOGBD_02244	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KNIHOGBD_02245	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KNIHOGBD_02246	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KNIHOGBD_02247	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KNIHOGBD_02248	6.91e-118	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KNIHOGBD_02249	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
KNIHOGBD_02250	9.63e-81	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
KNIHOGBD_02251	6.27e-50	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
KNIHOGBD_02252	2.64e-46	-	-	-	-	-	-	-	-
KNIHOGBD_02253	5.58e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
KNIHOGBD_02254	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KNIHOGBD_02256	0.0	-	-	-	E	-	-	-	Amino acid permease
KNIHOGBD_02257	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
KNIHOGBD_02258	4.31e-204	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KNIHOGBD_02260	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNIHOGBD_02261	1.49e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
KNIHOGBD_02262	2.33e-120	-	-	-	S	-	-	-	VanZ like family
KNIHOGBD_02263	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
KNIHOGBD_02264	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
KNIHOGBD_02265	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KNIHOGBD_02266	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
KNIHOGBD_02267	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
KNIHOGBD_02268	1.68e-55	-	-	-	-	-	-	-	-
KNIHOGBD_02269	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
KNIHOGBD_02270	3.69e-30	-	-	-	-	-	-	-	-
KNIHOGBD_02271	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
KNIHOGBD_02272	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNIHOGBD_02274	3.92e-189	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family