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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MDCKOFAN_00001	3.39e-88	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
MDCKOFAN_00002	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MDCKOFAN_00003	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
MDCKOFAN_00005	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDCKOFAN_00006	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MDCKOFAN_00007	3.11e-250	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MDCKOFAN_00008	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDCKOFAN_00009	3.72e-111	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MDCKOFAN_00010	3.91e-91	-	-	-	O	-	-	-	OsmC-like protein
MDCKOFAN_00011	6.74e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDCKOFAN_00012	2.27e-132	sptS	-	-	T	-	-	-	Histidine kinase
MDCKOFAN_00013	2.05e-146	sptS	-	-	T	-	-	-	Histidine kinase
MDCKOFAN_00014	1.52e-135	dltr	-	-	K	-	-	-	response regulator
MDCKOFAN_00015	1.19e-128	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
MDCKOFAN_00016	3.56e-47	-	-	-	-	-	-	-	-
MDCKOFAN_00017	4.13e-83	-	-	-	-	-	-	-	-
MDCKOFAN_00020	7.5e-160	-	-	-	-	-	-	-	-
MDCKOFAN_00021	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
MDCKOFAN_00022	1.24e-08	-	-	-	-	-	-	-	-
MDCKOFAN_00023	1.73e-48	-	-	-	-	-	-	-	-
MDCKOFAN_00024	9.39e-195	-	-	-	-	-	-	-	-
MDCKOFAN_00026	3.25e-315	-	-	-	M	-	-	-	Glycosyl transferase
MDCKOFAN_00027	1.03e-262	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MDCKOFAN_00028	8.66e-85	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00029	3.46e-18	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00030	5.66e-16	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00031	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MDCKOFAN_00032	4.92e-43	-	-	-	L	-	-	-	Transposase DDE domain
MDCKOFAN_00033	0.0	-	-	-	L	-	-	-	Transposase
MDCKOFAN_00034	6.69e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDCKOFAN_00035	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDCKOFAN_00036	1.23e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDCKOFAN_00037	3.42e-30	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MDCKOFAN_00038	7.19e-281	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDCKOFAN_00039	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDCKOFAN_00040	3.94e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MDCKOFAN_00042	2.63e-194	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_00045	3.05e-19	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_00047	2.78e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MDCKOFAN_00050	1.04e-06	-	-	-	K	-	-	-	Tetratricopeptide repeat
MDCKOFAN_00053	2.49e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
MDCKOFAN_00054	8.26e-56	-	-	-	S	-	-	-	ERF superfamily
MDCKOFAN_00055	1.3e-40	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_00056	2.6e-21	ansR	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_00058	5.95e-24	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MDCKOFAN_00062	3.9e-53	-	-	-	Q	-	-	-	methyltransferase
MDCKOFAN_00067	7.58e-90	-	-	-	S	-	-	-	ORF6C domain
MDCKOFAN_00069	8.55e-49	-	-	-	S	-	-	-	VRR_NUC
MDCKOFAN_00077	9.77e-27	-	-	-	S	-	-	-	N-methyltransferase activity
MDCKOFAN_00080	4.27e-234	-	-	-	S	-	-	-	Terminase-like family
MDCKOFAN_00081	2.32e-110	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
MDCKOFAN_00082	3.33e-70	-	-	-	S	-	-	-	Phage Mu protein F like protein
MDCKOFAN_00083	2.38e-28	-	-	-	S	-	-	-	Lysin motif
MDCKOFAN_00084	7.53e-73	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
MDCKOFAN_00085	8.98e-25	-	-	-	-	-	-	-	-
MDCKOFAN_00087	4.47e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4054)
MDCKOFAN_00088	5.56e-22	-	-	-	-	-	-	-	-
MDCKOFAN_00091	8.17e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MDCKOFAN_00094	1.18e-225	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDCKOFAN_00095	7.64e-54	-	-	-	M	-	-	-	LysM domain
MDCKOFAN_00096	9.82e-61	-	-	-	-	-	-	-	-
MDCKOFAN_00097	2.3e-128	-	-	-	-	-	-	-	-
MDCKOFAN_00098	4.1e-49	-	-	-	-	-	-	-	-
MDCKOFAN_00099	1.55e-40	-	-	-	-	-	-	-	-
MDCKOFAN_00100	4.11e-140	-	-	-	S	-	-	-	Baseplate J-like protein
MDCKOFAN_00102	3.95e-17	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MDCKOFAN_00105	1.01e-54	-	-	-	-	-	-	-	-
MDCKOFAN_00106	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
MDCKOFAN_00109	1.22e-24	-	-	-	-	-	-	-	-
MDCKOFAN_00110	9.28e-41	-	-	-	-	-	-	-	-
MDCKOFAN_00111	2.48e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MDCKOFAN_00112	5.3e-32	-	-	-	-	-	-	-	-
MDCKOFAN_00113	3.24e-45	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDCKOFAN_00114	3.98e-125	-	-	-	S	-	-	-	Phospholipase, patatin family
MDCKOFAN_00115	4.3e-188	-	-	-	S	-	-	-	hydrolase
MDCKOFAN_00116	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MDCKOFAN_00117	6.31e-84	-	-	-	-	-	-	-	-
MDCKOFAN_00118	6.84e-70	-	-	-	-	-	-	-	-
MDCKOFAN_00120	4.4e-165	-	-	-	S	-	-	-	PAS domain
MDCKOFAN_00122	4.26e-108	-	-	-	M	-	-	-	NlpC/P60 family
MDCKOFAN_00123	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MDCKOFAN_00124	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
MDCKOFAN_00125	8.56e-126	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_00126	2.75e-43	-	-	-	G	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MDCKOFAN_00127	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
MDCKOFAN_00128	1.48e-84	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00129	3.61e-85	-	-	-	L	-	-	-	DDE superfamily endonuclease
MDCKOFAN_00130	2.32e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDCKOFAN_00131	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MDCKOFAN_00132	3.37e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MDCKOFAN_00133	1.53e-122	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_00134	6.49e-137	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_00138	7.86e-72	-	-	-	S	-	-	-	Plasmid replication protein
MDCKOFAN_00140	3.14e-314	-	-	-	D	-	-	-	plasmid recombination enzyme
MDCKOFAN_00141	9.48e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
MDCKOFAN_00142	2.06e-88	-	-	-	-	-	-	-	-
MDCKOFAN_00143	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MDCKOFAN_00144	2.33e-230	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MDCKOFAN_00145	2.36e-213	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MDCKOFAN_00146	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDCKOFAN_00147	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MDCKOFAN_00148	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDCKOFAN_00149	2.43e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDCKOFAN_00150	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MDCKOFAN_00151	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MDCKOFAN_00152	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDCKOFAN_00153	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MDCKOFAN_00154	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDCKOFAN_00155	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_00156	3.41e-88	-	-	-	-	-	-	-	-
MDCKOFAN_00157	2.52e-32	-	-	-	-	-	-	-	-
MDCKOFAN_00158	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MDCKOFAN_00159	4.74e-107	-	-	-	-	-	-	-	-
MDCKOFAN_00160	7.87e-30	-	-	-	-	-	-	-	-
MDCKOFAN_00164	5.02e-180	blpT	-	-	-	-	-	-	-
MDCKOFAN_00165	4.85e-122	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MDCKOFAN_00166	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDCKOFAN_00167	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MDCKOFAN_00168	7.34e-178	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MDCKOFAN_00169	1.89e-23	-	-	-	-	-	-	-	-
MDCKOFAN_00170	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MDCKOFAN_00171	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MDCKOFAN_00172	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MDCKOFAN_00173	4.48e-34	-	-	-	-	-	-	-	-
MDCKOFAN_00174	1.07e-35	-	-	-	-	-	-	-	-
MDCKOFAN_00175	1.95e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00176	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
MDCKOFAN_00177	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MDCKOFAN_00178	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDCKOFAN_00179	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MDCKOFAN_00180	8.32e-157	vanR	-	-	K	-	-	-	response regulator
MDCKOFAN_00182	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDCKOFAN_00183	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_00184	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_00185	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MDCKOFAN_00186	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDCKOFAN_00187	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MDCKOFAN_00188	4.28e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDCKOFAN_00189	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MDCKOFAN_00190	5.86e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDCKOFAN_00191	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MDCKOFAN_00192	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
MDCKOFAN_00193	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDCKOFAN_00194	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDCKOFAN_00195	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDCKOFAN_00196	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDCKOFAN_00197	1.25e-143	-	-	-	K	-	-	-	WHG domain
MDCKOFAN_00198	2.63e-50	-	-	-	-	-	-	-	-
MDCKOFAN_00200	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDCKOFAN_00201	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDCKOFAN_00202	3.64e-188	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MDCKOFAN_00203	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MDCKOFAN_00204	6.15e-36	-	-	-	-	-	-	-	-
MDCKOFAN_00205	1.41e-87	-	-	-	V	-	-	-	HNH endonuclease
MDCKOFAN_00207	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MDCKOFAN_00208	6.45e-291	-	-	-	E	-	-	-	amino acid
MDCKOFAN_00209	3.98e-97	-	-	-	M	-	-	-	LysM domain
MDCKOFAN_00210	3.3e-42	-	-	-	-	-	-	-	-
MDCKOFAN_00212	3.74e-125	-	-	-	-	-	-	-	-
MDCKOFAN_00213	2.75e-96	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MDCKOFAN_00214	5.22e-05	-	-	-	-	-	-	-	-
MDCKOFAN_00215	4.7e-183	pct	2.8.3.1	-	I	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	ko00000,ko00001,ko01000	Coenzyme A transferase
MDCKOFAN_00216	5.89e-192	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MDCKOFAN_00217	5.34e-143	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Enoyl-CoA hydratase/isomerase
MDCKOFAN_00218	1.64e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00219	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDCKOFAN_00220	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDCKOFAN_00223	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MDCKOFAN_00224	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MDCKOFAN_00225	1.08e-69	-	-	-	L	-	-	-	Transposase and inactivated derivatives
MDCKOFAN_00226	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MDCKOFAN_00227	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_00228	2.1e-31	-	-	-	-	-	-	-	-
MDCKOFAN_00229	1.69e-06	-	-	-	-	-	-	-	-
MDCKOFAN_00230	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDCKOFAN_00231	1.72e-228	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDCKOFAN_00232	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MDCKOFAN_00233	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDCKOFAN_00234	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_00235	4.14e-154	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_00236	1.49e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_00237	4.31e-231	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_00238	5.15e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_00239	4.4e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDCKOFAN_00240	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDCKOFAN_00241	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDCKOFAN_00242	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MDCKOFAN_00243	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MDCKOFAN_00244	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MDCKOFAN_00245	2.29e-41	-	-	-	-	-	-	-	-
MDCKOFAN_00246	9.44e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MDCKOFAN_00247	7.49e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDCKOFAN_00248	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDCKOFAN_00249	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDCKOFAN_00250	3.28e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MDCKOFAN_00251	1.84e-309	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDCKOFAN_00252	5.15e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDCKOFAN_00253	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDCKOFAN_00254	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDCKOFAN_00255	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MDCKOFAN_00256	2.19e-100	-	-	-	S	-	-	-	ASCH
MDCKOFAN_00257	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MDCKOFAN_00258	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MDCKOFAN_00259	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDCKOFAN_00260	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDCKOFAN_00261	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDCKOFAN_00262	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDCKOFAN_00263	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDCKOFAN_00264	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MDCKOFAN_00265	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDCKOFAN_00266	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDCKOFAN_00267	3.94e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MDCKOFAN_00268	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MDCKOFAN_00269	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDCKOFAN_00270	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MDCKOFAN_00271	1.82e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MDCKOFAN_00272	3.28e-115	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDCKOFAN_00273	4.73e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
MDCKOFAN_00274	2.72e-05	-	-	-	M	ko:K11021	-	ko00000,ko02042	COG3209 Rhs family protein
MDCKOFAN_00276	8.25e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
MDCKOFAN_00277	4.26e-27	-	-	-	E	-	-	-	Pfam:DUF955
MDCKOFAN_00278	1.91e-233	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDCKOFAN_00280	7.57e-190	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
MDCKOFAN_00281	1.64e-19	-	-	-	-	-	-	-	-
MDCKOFAN_00282	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MDCKOFAN_00283	6.64e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MDCKOFAN_00284	1.05e-176	-	-	-	F	-	-	-	Phosphorylase superfamily
MDCKOFAN_00288	1.87e-104	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDCKOFAN_00289	7.12e-100	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MDCKOFAN_00290	2.05e-96	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MDCKOFAN_00291	2.71e-222	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MDCKOFAN_00292	6.46e-27	-	-	-	-	-	-	-	-
MDCKOFAN_00293	1.12e-268	-	-	-	-	-	-	-	-
MDCKOFAN_00294	6.57e-175	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_00295	1.14e-154	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_00296	1.06e-133	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MDCKOFAN_00297	2.35e-58	-	-	-	-	-	-	-	-
MDCKOFAN_00298	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_00299	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
MDCKOFAN_00300	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDCKOFAN_00301	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDCKOFAN_00302	5.38e-39	-	-	-	-	-	-	-	-
MDCKOFAN_00303	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDCKOFAN_00304	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDCKOFAN_00305	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDCKOFAN_00306	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDCKOFAN_00307	2.65e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDCKOFAN_00308	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MDCKOFAN_00309	7.67e-252	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00310	9.14e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDCKOFAN_00311	8.11e-245	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDCKOFAN_00312	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MDCKOFAN_00313	4.22e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDCKOFAN_00314	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDCKOFAN_00315	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDCKOFAN_00316	6.72e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MDCKOFAN_00317	4.83e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDCKOFAN_00318	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDCKOFAN_00319	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MDCKOFAN_00320	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDCKOFAN_00321	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MDCKOFAN_00322	5.56e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MDCKOFAN_00323	2.26e-215	degV1	-	-	S	-	-	-	DegV family
MDCKOFAN_00324	1.23e-170	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_00325	4.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MDCKOFAN_00326	3.81e-18	-	-	-	S	-	-	-	CsbD-like
MDCKOFAN_00327	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
MDCKOFAN_00328	1.37e-287	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MDCKOFAN_00329	3.92e-153	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MDCKOFAN_00331	6.48e-167	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_00332	4.95e-98	-	-	-	-	-	-	-	-
MDCKOFAN_00333	6.59e-115	-	-	-	-	-	-	-	-
MDCKOFAN_00334	8.6e-128	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
MDCKOFAN_00335	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MDCKOFAN_00336	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MDCKOFAN_00337	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDCKOFAN_00338	4.52e-29	-	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_00339	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MDCKOFAN_00340	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MDCKOFAN_00342	5.51e-35	-	-	-	-	-	-	-	-
MDCKOFAN_00343	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MDCKOFAN_00344	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
MDCKOFAN_00345	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
MDCKOFAN_00346	0.0	-	-	-	L	-	-	-	PLD-like domain
MDCKOFAN_00347	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
MDCKOFAN_00348	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDCKOFAN_00349	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MDCKOFAN_00350	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MDCKOFAN_00351	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDCKOFAN_00352	3.06e-140	-	-	-	-	-	-	-	-
MDCKOFAN_00353	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDCKOFAN_00355	4.88e-12	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDCKOFAN_00356	6.69e-155	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_00358	1.64e-73	-	-	-	V	-	-	-	Abi-like protein
MDCKOFAN_00359	8.17e-84	-	-	-	K	-	-	-	Peptidase S24-like
MDCKOFAN_00366	2.38e-28	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MDCKOFAN_00370	1.75e-104	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_00371	2.73e-103	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MDCKOFAN_00374	1.85e-12	-	-	-	-	-	-	-	-
MDCKOFAN_00375	3.93e-20	-	-	-	S	-	-	-	HNH endonuclease
MDCKOFAN_00384	3.49e-48	-	-	-	L	-	-	-	HNH endonuclease
MDCKOFAN_00386	0.000922	-	-	-	S	-	-	-	Phage terminase, small subunit
MDCKOFAN_00387	2.77e-220	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
MDCKOFAN_00389	5.61e-125	-	-	-	S	-	-	-	Phage portal protein
MDCKOFAN_00390	2.3e-70	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
MDCKOFAN_00391	5.72e-108	-	-	-	S	-	-	-	Phage capsid family
MDCKOFAN_00394	9.66e-39	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MDCKOFAN_00399	1.9e-185	-	-	-	D	-	-	-	domain protein
MDCKOFAN_00400	2.14e-48	-	-	-	-	-	-	-	-
MDCKOFAN_00401	1.14e-208	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MDCKOFAN_00402	5.69e-179	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_00403	2.18e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_00404	4.82e-144	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_00407	2.61e-30	-	-	-	-	-	-	-	-
MDCKOFAN_00408	2.91e-217	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDCKOFAN_00409	9.03e-257	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MDCKOFAN_00410	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MDCKOFAN_00422	1.14e-28	-	-	-	-	-	-	-	-
MDCKOFAN_00428	6.01e-66	-	-	-	-	-	-	-	-
MDCKOFAN_00432	1.51e-76	-	-	-	-	-	-	-	-
MDCKOFAN_00433	6.65e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00435	2.46e-207	-	-	-	S	-	-	-	Baseplate J-like protein
MDCKOFAN_00437	1.61e-58	-	-	-	-	-	-	-	-
MDCKOFAN_00438	1.43e-143	-	-	-	-	-	-	-	-
MDCKOFAN_00439	9.3e-57	-	-	-	-	-	-	-	-
MDCKOFAN_00440	4.47e-105	-	-	-	M	-	-	-	LysM domain
MDCKOFAN_00441	2.69e-272	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDCKOFAN_00445	4.04e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MDCKOFAN_00448	9.75e-36	-	-	-	-	-	-	-	-
MDCKOFAN_00451	8.2e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00452	2.04e-78	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
MDCKOFAN_00453	4.13e-28	-	-	-	S	-	-	-	Lysin motif
MDCKOFAN_00454	4.88e-85	-	-	-	S	-	-	-	Phage Mu protein F like protein
MDCKOFAN_00455	4.55e-138	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
MDCKOFAN_00456	1.36e-248	-	-	-	S	-	-	-	Terminase-like family
MDCKOFAN_00457	2.92e-26	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MDCKOFAN_00459	1.75e-20	bcgIA	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
MDCKOFAN_00460	1.97e-88	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
MDCKOFAN_00465	4.36e-272	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MDCKOFAN_00467	6.94e-54	-	-	-	S	-	-	-	VRR_NUC
MDCKOFAN_00469	8.99e-59	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MDCKOFAN_00470	1.5e-150	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
MDCKOFAN_00471	1.83e-103	-	-	-	S	-	-	-	AAA domain
MDCKOFAN_00472	9.82e-80	-	-	-	F	-	-	-	NUDIX domain
MDCKOFAN_00473	1.23e-125	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MDCKOFAN_00474	2e-299	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDCKOFAN_00475	5.28e-215	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MDCKOFAN_00476	3.53e-63	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MDCKOFAN_00477	1.55e-82	-	-	-	M	-	-	-	SIS domain
MDCKOFAN_00478	8.46e-98	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MDCKOFAN_00479	1.88e-44	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDCKOFAN_00480	3.94e-254	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDCKOFAN_00481	3.05e-53	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_00482	2.39e-85	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDCKOFAN_00483	2.76e-188	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MDCKOFAN_00484	1.92e-90	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDCKOFAN_00486	2.94e-94	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MDCKOFAN_00487	5.18e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDCKOFAN_00488	2.56e-66	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
MDCKOFAN_00489	2.38e-130	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MDCKOFAN_00490	2.82e-97	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
MDCKOFAN_00491	1.53e-102	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
MDCKOFAN_00492	5.25e-137	-	-	-	M	-	-	-	Glycosyltransferase
MDCKOFAN_00493	6.23e-40	-	-	-	M	-	-	-	Glycosyltransferase
MDCKOFAN_00494	3.85e-154	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MDCKOFAN_00495	6.64e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MDCKOFAN_00496	2.78e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MDCKOFAN_00497	4.34e-184	epsB	-	-	M	-	-	-	biosynthesis protein
MDCKOFAN_00498	1.47e-243	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDCKOFAN_00502	1.3e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDCKOFAN_00503	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MDCKOFAN_00504	3.01e-54	-	-	-	-	-	-	-	-
MDCKOFAN_00505	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MDCKOFAN_00506	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MDCKOFAN_00507	4.39e-116	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MDCKOFAN_00508	2.11e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MDCKOFAN_00509	4.52e-56	-	-	-	-	-	-	-	-
MDCKOFAN_00510	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MDCKOFAN_00511	8.77e-144	-	-	-	-	-	-	-	-
MDCKOFAN_00512	6.96e-286	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MDCKOFAN_00513	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MDCKOFAN_00514	3.4e-227	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDCKOFAN_00515	1.16e-101	-	-	-	-	-	-	-	-
MDCKOFAN_00516	2.72e-144	-	-	-	S	-	-	-	Peptidase_C39 like family
MDCKOFAN_00517	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MDCKOFAN_00518	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDCKOFAN_00519	0.0	-	-	-	S	-	-	-	ABC transporter
MDCKOFAN_00520	1.64e-81	-	-	-	-	-	-	-	-
MDCKOFAN_00521	1.1e-125	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDCKOFAN_00522	2.8e-160	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MDCKOFAN_00523	7.9e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDCKOFAN_00524	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MDCKOFAN_00525	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
MDCKOFAN_00526	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MDCKOFAN_00527	1.8e-222	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_00528	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MDCKOFAN_00529	2.92e-79	-	-	-	-	-	-	-	-
MDCKOFAN_00530	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_00531	1.66e-44	-	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_00532	1.12e-213	-	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_00533	5.52e-49	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MDCKOFAN_00534	3.01e-73	-	-	-	-	-	-	-	-
MDCKOFAN_00535	2.31e-77	-	-	-	GK	-	-	-	ROK family
MDCKOFAN_00536	3.1e-92	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MDCKOFAN_00537	2.86e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDCKOFAN_00538	3.52e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDCKOFAN_00539	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDCKOFAN_00540	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDCKOFAN_00541	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MDCKOFAN_00542	1.47e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MDCKOFAN_00543	1.35e-56	-	-	-	-	-	-	-	-
MDCKOFAN_00544	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
MDCKOFAN_00545	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MDCKOFAN_00546	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MDCKOFAN_00547	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MDCKOFAN_00548	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MDCKOFAN_00549	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MDCKOFAN_00550	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MDCKOFAN_00551	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDCKOFAN_00552	1.48e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDCKOFAN_00553	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDCKOFAN_00554	6.55e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDCKOFAN_00555	2.48e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDCKOFAN_00556	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDCKOFAN_00557	5.87e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MDCKOFAN_00558	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDCKOFAN_00559	1.66e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDCKOFAN_00560	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDCKOFAN_00561	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDCKOFAN_00562	7.02e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MDCKOFAN_00563	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MDCKOFAN_00566	7.95e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_00567	3.26e-274	-	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_00568	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MDCKOFAN_00569	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
MDCKOFAN_00570	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDCKOFAN_00571	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MDCKOFAN_00572	4.96e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MDCKOFAN_00573	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
MDCKOFAN_00574	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDCKOFAN_00575	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MDCKOFAN_00576	1.72e-127	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MDCKOFAN_00578	1e-22	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MDCKOFAN_00579	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDCKOFAN_00580	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MDCKOFAN_00581	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MDCKOFAN_00582	1.64e-90	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MDCKOFAN_00583	9e-132	-	-	-	L	-	-	-	Integrase
MDCKOFAN_00585	1.28e-162	sagD	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MDCKOFAN_00586	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDCKOFAN_00587	1.56e-155	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MDCKOFAN_00588	8.62e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MDCKOFAN_00589	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCKOFAN_00590	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MDCKOFAN_00591	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDCKOFAN_00592	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDCKOFAN_00593	4.84e-42	-	-	-	-	-	-	-	-
MDCKOFAN_00594	2.96e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_00595	2.52e-151	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_00596	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDCKOFAN_00597	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MDCKOFAN_00598	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MDCKOFAN_00599	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MDCKOFAN_00600	2.82e-110	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_00601	3.16e-52	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDCKOFAN_00602	1.74e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDCKOFAN_00603	4e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MDCKOFAN_00604	7.38e-168	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDCKOFAN_00605	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDCKOFAN_00606	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDCKOFAN_00607	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDCKOFAN_00608	4.87e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MDCKOFAN_00609	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MDCKOFAN_00610	3.22e-185	-	-	-	K	-	-	-	rpiR family
MDCKOFAN_00611	5.06e-237	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MDCKOFAN_00612	7.56e-225	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase
MDCKOFAN_00613	1.54e-194	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDCKOFAN_00614	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDCKOFAN_00615	5.03e-313	mdr	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_00616	1.72e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDCKOFAN_00619	1.35e-191	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDCKOFAN_00620	2.78e-70	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MDCKOFAN_00621	7.02e-36	-	-	-	-	-	-	-	-
MDCKOFAN_00622	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDCKOFAN_00623	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDCKOFAN_00624	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MDCKOFAN_00625	9.67e-104	-	-	-	-	-	-	-	-
MDCKOFAN_00626	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDCKOFAN_00627	6.85e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MDCKOFAN_00628	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDCKOFAN_00629	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MDCKOFAN_00630	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDCKOFAN_00631	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MDCKOFAN_00632	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDCKOFAN_00633	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MDCKOFAN_00634	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MDCKOFAN_00635	9.62e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MDCKOFAN_00636	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MDCKOFAN_00637	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MDCKOFAN_00638	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDCKOFAN_00639	2.12e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MDCKOFAN_00640	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MDCKOFAN_00641	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MDCKOFAN_00642	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDCKOFAN_00643	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDCKOFAN_00644	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MDCKOFAN_00645	4.4e-215	-	-	-	-	-	-	-	-
MDCKOFAN_00646	4.68e-183	-	-	-	-	-	-	-	-
MDCKOFAN_00647	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDCKOFAN_00648	3.49e-36	-	-	-	-	-	-	-	-
MDCKOFAN_00649	3.85e-193	-	-	-	-	-	-	-	-
MDCKOFAN_00650	2.54e-176	-	-	-	-	-	-	-	-
MDCKOFAN_00651	1.65e-180	-	-	-	-	-	-	-	-
MDCKOFAN_00652	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDCKOFAN_00653	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MDCKOFAN_00654	4.97e-122	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDCKOFAN_00655	3.02e-151	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDCKOFAN_00656	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDCKOFAN_00657	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MDCKOFAN_00658	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MDCKOFAN_00659	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
MDCKOFAN_00660	2.4e-163	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_00661	2.82e-17	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDCKOFAN_00662	2.73e-21	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDCKOFAN_00663	6.8e-48	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MDCKOFAN_00664	4.82e-102	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MDCKOFAN_00665	5.44e-299	-	-	-	V	-	-	-	N-6 DNA Methylase
MDCKOFAN_00666	9.56e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MDCKOFAN_00667	1.71e-156	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MDCKOFAN_00668	7.98e-35	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_00669	4.68e-25	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDCKOFAN_00670	8.24e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDCKOFAN_00671	7.62e-32	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_00673	1.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MDCKOFAN_00674	5.85e-67	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MDCKOFAN_00676	1.54e-87	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MDCKOFAN_00677	2.78e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00678	1.51e-27	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDCKOFAN_00680	2.72e-158	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MDCKOFAN_00682	1.33e-22	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDCKOFAN_00683	1.69e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MDCKOFAN_00684	4.16e-55	-	-	-	E	-	-	-	Pfam:DUF955
MDCKOFAN_00686	2.63e-24	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MDCKOFAN_00687	1.72e-33	-	-	-	L	-	-	-	four-way junction helicase activity
MDCKOFAN_00696	2.23e-24	lysM	-	-	M	-	-	-	LysM domain
MDCKOFAN_00697	3.25e-194	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MDCKOFAN_00701	1.14e-163	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MDCKOFAN_00706	3.76e-13	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_00707	6.55e-05	-	-	-	M	-	-	-	Conserved repeat domain
MDCKOFAN_00708	2.46e-10	-	-	-	M	-	-	-	oxidoreductase activity
MDCKOFAN_00710	3.61e-20	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MDCKOFAN_00711	2.48e-15	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_00715	2.59e-10	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDCKOFAN_00723	2.38e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MDCKOFAN_00724	9.39e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_00725	5.58e-33	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_00726	3.74e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MDCKOFAN_00728	2.63e-194	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_00731	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDCKOFAN_00732	4.37e-241	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MDCKOFAN_00733	3.69e-30	-	-	-	-	-	-	-	-
MDCKOFAN_00734	1.31e-98	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MDCKOFAN_00735	1.96e-54	-	-	-	-	-	-	-	-
MDCKOFAN_00736	8.52e-93	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MDCKOFAN_00737	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MDCKOFAN_00738	5.15e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MDCKOFAN_00739	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MDCKOFAN_00740	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MDCKOFAN_00741	3.31e-120	-	-	-	S	-	-	-	VanZ like family
MDCKOFAN_00742	7.83e-140	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MDCKOFAN_00743	4.8e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDCKOFAN_00745	0.0	-	-	-	E	-	-	-	Amino acid permease
MDCKOFAN_00746	5.92e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MDCKOFAN_00747	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDCKOFAN_00748	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDCKOFAN_00749	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MDCKOFAN_00750	1.25e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MDCKOFAN_00751	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDCKOFAN_00752	2.85e-153	-	-	-	-	-	-	-	-
MDCKOFAN_00753	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MDCKOFAN_00754	8.04e-190	-	-	-	S	-	-	-	hydrolase
MDCKOFAN_00755	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDCKOFAN_00756	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
MDCKOFAN_00757	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDCKOFAN_00758	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_00759	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_00760	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_00761	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDCKOFAN_00762	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MDCKOFAN_00763	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDCKOFAN_00764	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MDCKOFAN_00765	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MDCKOFAN_00766	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDCKOFAN_00767	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDCKOFAN_00768	3.07e-124	-	-	-	-	-	-	-	-
MDCKOFAN_00769	6.12e-94	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MDCKOFAN_00770	7.14e-91	-	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_00771	2.58e-45	-	-	-	-	-	-	-	-
MDCKOFAN_00773	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MDCKOFAN_00774	1.46e-117	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDCKOFAN_00775	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_00780	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDCKOFAN_00781	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDCKOFAN_00782	5.63e-254	flp	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_00783	7.58e-291	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MDCKOFAN_00784	1.64e-65	-	-	-	-	-	-	-	-
MDCKOFAN_00785	4.83e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDCKOFAN_00786	4.45e-84	-	-	-	K	-	-	-	transcriptional regulator
MDCKOFAN_00788	3.93e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MDCKOFAN_00789	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDCKOFAN_00790	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDCKOFAN_00791	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDCKOFAN_00792	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
MDCKOFAN_00793	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDCKOFAN_00794	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MDCKOFAN_00795	3.29e-127	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MDCKOFAN_00797	2.24e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MDCKOFAN_00798	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MDCKOFAN_00799	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDCKOFAN_00800	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDCKOFAN_00801	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDCKOFAN_00802	4e-260	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MDCKOFAN_00803	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDCKOFAN_00804	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDCKOFAN_00805	2.94e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
MDCKOFAN_00806	2.13e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDCKOFAN_00808	4.5e-235	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDCKOFAN_00809	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MDCKOFAN_00810	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MDCKOFAN_00811	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MDCKOFAN_00812	3.57e-204	-	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_00813	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MDCKOFAN_00814	1.38e-309	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDCKOFAN_00815	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MDCKOFAN_00816	1.14e-144	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MDCKOFAN_00817	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDCKOFAN_00818	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MDCKOFAN_00819	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDCKOFAN_00820	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_00821	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MDCKOFAN_00822	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDCKOFAN_00823	2.53e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDCKOFAN_00824	3.36e-42	-	-	-	-	-	-	-	-
MDCKOFAN_00825	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MDCKOFAN_00826	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_00827	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MDCKOFAN_00828	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MDCKOFAN_00829	0.0	-	-	-	S	-	-	-	TerB-C domain
MDCKOFAN_00830	4.13e-310	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
MDCKOFAN_00831	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MDCKOFAN_00832	7.82e-80	-	-	-	-	-	-	-	-
MDCKOFAN_00833	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MDCKOFAN_00834	6.58e-175	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MDCKOFAN_00836	4.51e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MDCKOFAN_00837	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MDCKOFAN_00838	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MDCKOFAN_00840	1.04e-41	-	-	-	-	-	-	-	-
MDCKOFAN_00841	2.77e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MDCKOFAN_00842	1.25e-17	-	-	-	-	-	-	-	-
MDCKOFAN_00843	9.13e-157	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MDCKOFAN_00844	3.79e-175	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MDCKOFAN_00845	7.36e-135	-	-	-	C	-	-	-	Flavodoxin
MDCKOFAN_00846	2.27e-191	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MDCKOFAN_00847	1.8e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDCKOFAN_00848	2.39e-26	-	-	-	-	-	-	-	-
MDCKOFAN_00849	1.79e-245	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MDCKOFAN_00850	1.86e-197	-	-	-	M	-	-	-	Peptidase family M1 domain
MDCKOFAN_00851	9.84e-108	-	-	-	L	-	-	-	Resolvase, N-terminal
MDCKOFAN_00852	4.5e-107	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MDCKOFAN_00853	4.2e-93	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MDCKOFAN_00854	7.29e-220	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_00855	3.31e-299	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MDCKOFAN_00856	2.23e-314	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDCKOFAN_00857	5.28e-251	-	-	-	-	-	-	-	-
MDCKOFAN_00858	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDCKOFAN_00859	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
MDCKOFAN_00861	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDCKOFAN_00862	5.7e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDCKOFAN_00863	1.05e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_00864	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MDCKOFAN_00865	1.2e-41	-	-	-	-	-	-	-	-
MDCKOFAN_00866	1.09e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDCKOFAN_00867	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
MDCKOFAN_00868	0.0	-	-	-	-	-	-	-	-
MDCKOFAN_00869	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
MDCKOFAN_00871	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDCKOFAN_00872	0.0	yhaN	-	-	L	-	-	-	AAA domain
MDCKOFAN_00873	1.88e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MDCKOFAN_00874	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MDCKOFAN_00875	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDCKOFAN_00876	2.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDCKOFAN_00877	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MDCKOFAN_00878	1.49e-13	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MDCKOFAN_00879	1.91e-102	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MDCKOFAN_00880	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDCKOFAN_00882	1.27e-42	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MDCKOFAN_00883	3.24e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MDCKOFAN_00884	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
MDCKOFAN_00886	1.44e-234	-	-	-	L	-	-	-	Phage integrase family
MDCKOFAN_00887	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MDCKOFAN_00888	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDCKOFAN_00889	1.06e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDCKOFAN_00890	5.12e-174	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCKOFAN_00891	5.5e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCKOFAN_00892	1.02e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCKOFAN_00893	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MDCKOFAN_00894	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCKOFAN_00895	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDCKOFAN_00896	3.44e-72	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDCKOFAN_00897	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MDCKOFAN_00898	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDCKOFAN_00899	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDCKOFAN_00900	1.25e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDCKOFAN_00901	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDCKOFAN_00902	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MDCKOFAN_00903	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDCKOFAN_00904	2.8e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDCKOFAN_00905	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDCKOFAN_00906	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDCKOFAN_00907	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDCKOFAN_00908	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDCKOFAN_00909	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDCKOFAN_00910	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDCKOFAN_00911	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDCKOFAN_00912	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MDCKOFAN_00913	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDCKOFAN_00914	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDCKOFAN_00915	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDCKOFAN_00916	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDCKOFAN_00917	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDCKOFAN_00918	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDCKOFAN_00919	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MDCKOFAN_00920	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDCKOFAN_00921	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MDCKOFAN_00922	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDCKOFAN_00923	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDCKOFAN_00924	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDCKOFAN_00925	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MDCKOFAN_00926	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCKOFAN_00927	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCKOFAN_00928	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDCKOFAN_00929	1.92e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MDCKOFAN_00933	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MDCKOFAN_00934	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDCKOFAN_00935	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDCKOFAN_00936	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDCKOFAN_00937	2.14e-231	-	-	-	M	-	-	-	CHAP domain
MDCKOFAN_00938	2.79e-102	-	-	-	-	-	-	-	-
MDCKOFAN_00939	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDCKOFAN_00940	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDCKOFAN_00941	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDCKOFAN_00942	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDCKOFAN_00943	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDCKOFAN_00944	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDCKOFAN_00945	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MDCKOFAN_00946	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDCKOFAN_00947	6.15e-268	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDCKOFAN_00948	7.44e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MDCKOFAN_00949	1.32e-305	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDCKOFAN_00950	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDCKOFAN_00951	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MDCKOFAN_00952	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDCKOFAN_00953	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MDCKOFAN_00954	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDCKOFAN_00955	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDCKOFAN_00956	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDCKOFAN_00957	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MDCKOFAN_00958	2.91e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDCKOFAN_00959	2.43e-145	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDCKOFAN_00961	2.84e-150	-	-	-	K	-	-	-	sequence-specific DNA binding
MDCKOFAN_00962	7.95e-06	-	-	-	-	-	-	-	-
MDCKOFAN_00964	8.56e-181	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MDCKOFAN_00965	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDCKOFAN_00966	3.09e-71	-	-	-	-	-	-	-	-
MDCKOFAN_00967	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
MDCKOFAN_00968	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
MDCKOFAN_00969	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MDCKOFAN_00970	5.81e-310	ynbB	-	-	P	-	-	-	aluminum resistance
MDCKOFAN_00971	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MDCKOFAN_00972	0.0	-	-	-	E	-	-	-	Amino acid permease
MDCKOFAN_00973	9.58e-122	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MDCKOFAN_00974	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MDCKOFAN_00975	2.47e-144	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDCKOFAN_00976	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MDCKOFAN_00977	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDCKOFAN_00978	9.28e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDCKOFAN_00979	3.71e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MDCKOFAN_00980	8.85e-121	-	-	-	M	-	-	-	LysM domain protein
MDCKOFAN_00981	6.42e-110	-	-	-	C	-	-	-	Aldo keto reductase
MDCKOFAN_00982	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDCKOFAN_00983	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDCKOFAN_00984	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDCKOFAN_00985	5.99e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MDCKOFAN_00986	8.35e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDCKOFAN_00987	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDCKOFAN_00988	1.5e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MDCKOFAN_00989	1e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDCKOFAN_00990	2.15e-198	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDCKOFAN_00991	2.4e-118	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MDCKOFAN_00992	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MDCKOFAN_00993	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
MDCKOFAN_00994	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MDCKOFAN_00995	8.83e-187	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MDCKOFAN_00996	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MDCKOFAN_00997	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDCKOFAN_00998	1.15e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDCKOFAN_00999	9.58e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MDCKOFAN_01000	1.01e-240	yagE	-	-	E	-	-	-	Amino acid permease
MDCKOFAN_01001	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDCKOFAN_01002	1.07e-179	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDCKOFAN_01003	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MDCKOFAN_01004	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MDCKOFAN_01005	9.52e-205	yvgN	-	-	C	-	-	-	Aldo keto reductase
MDCKOFAN_01006	7.2e-202	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MDCKOFAN_01007	6.37e-169	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDCKOFAN_01008	9.61e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MDCKOFAN_01009	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDCKOFAN_01010	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01011	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MDCKOFAN_01012	2.55e-26	-	-	-	-	-	-	-	-
MDCKOFAN_01013	3.93e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDCKOFAN_01014	4.4e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
MDCKOFAN_01015	5.18e-135	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_01016	3.62e-264	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_01017	3.82e-149	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDCKOFAN_01018	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MDCKOFAN_01019	4.13e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MDCKOFAN_01020	2.23e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MDCKOFAN_01022	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
MDCKOFAN_01024	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01025	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
MDCKOFAN_01027	4.65e-30	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_01029	1.22e-98	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDCKOFAN_01030	1.7e-69	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDCKOFAN_01031	5.62e-134	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDCKOFAN_01032	1.52e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
MDCKOFAN_01033	2.53e-287	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01035	2.77e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MDCKOFAN_01036	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDCKOFAN_01037	6.16e-14	-	-	-	-	-	-	-	-
MDCKOFAN_01038	8.75e-197	-	-	-	-	-	-	-	-
MDCKOFAN_01039	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
MDCKOFAN_01040	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MDCKOFAN_01041	4.71e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MDCKOFAN_01042	4.65e-14	-	-	-	-	-	-	-	-
MDCKOFAN_01043	1.42e-57	-	-	-	-	-	-	-	-
MDCKOFAN_01044	7.34e-86	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDCKOFAN_01045	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDCKOFAN_01046	2.7e-162	-	-	-	-	-	-	-	-
MDCKOFAN_01047	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
MDCKOFAN_01048	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MDCKOFAN_01049	1.02e-148	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MDCKOFAN_01050	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDCKOFAN_01051	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01052	6.89e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MDCKOFAN_01053	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_01054	2.34e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDCKOFAN_01055	1.13e-126	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDCKOFAN_01056	1.43e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDCKOFAN_01057	5.16e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDCKOFAN_01059	1.02e-74	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDCKOFAN_01060	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MDCKOFAN_01061	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCKOFAN_01062	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCKOFAN_01063	3.01e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MDCKOFAN_01064	2.29e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDCKOFAN_01065	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDCKOFAN_01066	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDCKOFAN_01067	3.82e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDCKOFAN_01068	1.23e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDCKOFAN_01069	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDCKOFAN_01070	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDCKOFAN_01071	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MDCKOFAN_01072	1.19e-45	-	-	-	-	-	-	-	-
MDCKOFAN_01073	3.81e-123	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MDCKOFAN_01074	1.56e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDCKOFAN_01075	4.95e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDCKOFAN_01076	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDCKOFAN_01077	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDCKOFAN_01078	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDCKOFAN_01079	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MDCKOFAN_01080	2.23e-69	-	-	-	-	-	-	-	-
MDCKOFAN_01081	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDCKOFAN_01082	1.99e-235	-	-	-	S	-	-	-	AAA domain
MDCKOFAN_01083	3.43e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDCKOFAN_01084	2.42e-33	-	-	-	-	-	-	-	-
MDCKOFAN_01085	8.43e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MDCKOFAN_01086	3.16e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MDCKOFAN_01087	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
MDCKOFAN_01088	1.45e-74	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01089	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01090	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_01091	5.5e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_01092	7e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_01093	9.37e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MDCKOFAN_01094	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MDCKOFAN_01095	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDCKOFAN_01096	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MDCKOFAN_01097	1.42e-42	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MDCKOFAN_01098	3.2e-28	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MDCKOFAN_01099	3.15e-259	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDCKOFAN_01100	6.1e-228	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MDCKOFAN_01101	3.56e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDCKOFAN_01102	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDCKOFAN_01103	2.61e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDCKOFAN_01104	1.3e-31	-	-	-	-	-	-	-	-
MDCKOFAN_01105	1.34e-175	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01107	1.49e-151	-	-	-	V	-	-	-	Abi-like protein
MDCKOFAN_01108	5.19e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
MDCKOFAN_01109	3.28e-133	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_01110	9.7e-127	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_01111	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MDCKOFAN_01112	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDCKOFAN_01113	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MDCKOFAN_01114	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDCKOFAN_01115	5.28e-193	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDCKOFAN_01116	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
MDCKOFAN_01117	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MDCKOFAN_01118	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MDCKOFAN_01119	1.77e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDCKOFAN_01120	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MDCKOFAN_01121	5.95e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDCKOFAN_01122	8.01e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MDCKOFAN_01123	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MDCKOFAN_01124	3.52e-163	csrR	-	-	K	-	-	-	response regulator
MDCKOFAN_01125	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDCKOFAN_01126	2.19e-18	-	-	-	-	-	-	-	-
MDCKOFAN_01127	4.28e-125	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDCKOFAN_01128	4.76e-170	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01129	2.05e-107	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01130	1.13e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MDCKOFAN_01131	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDCKOFAN_01132	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MDCKOFAN_01133	1.37e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDCKOFAN_01134	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MDCKOFAN_01136	1.81e-139	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MDCKOFAN_01137	1.96e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01138	7.91e-164	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01139	1.2e-202	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_01140	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDCKOFAN_01141	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDCKOFAN_01142	2.55e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDCKOFAN_01143	3.9e-213	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDCKOFAN_01144	5.88e-181	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDCKOFAN_01145	1.8e-34	-	-	-	-	-	-	-	-
MDCKOFAN_01146	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MDCKOFAN_01147	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDCKOFAN_01148	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_01149	8.29e-294	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MDCKOFAN_01150	2.48e-313	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
MDCKOFAN_01151	3.2e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MDCKOFAN_01152	2.04e-60	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MDCKOFAN_01153	4.34e-64	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDCKOFAN_01154	3.7e-164	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01155	1.75e-120	-	-	-	-	-	-	-	-
MDCKOFAN_01157	4.07e-158	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MDCKOFAN_01158	1.7e-202	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MDCKOFAN_01159	2.2e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCKOFAN_01160	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
MDCKOFAN_01161	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDCKOFAN_01162	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MDCKOFAN_01163	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDCKOFAN_01164	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MDCKOFAN_01165	0.0	-	-	-	S	-	-	-	membrane
MDCKOFAN_01166	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDCKOFAN_01167	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDCKOFAN_01168	1.94e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDCKOFAN_01169	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MDCKOFAN_01170	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MDCKOFAN_01171	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MDCKOFAN_01172	1.9e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDCKOFAN_01173	1.74e-282	ynbB	-	-	P	-	-	-	aluminum resistance
MDCKOFAN_01174	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MDCKOFAN_01175	9.64e-219	-	-	-	-	-	-	-	-
MDCKOFAN_01176	1.21e-204	-	-	-	-	-	-	-	-
MDCKOFAN_01180	6.78e-47	-	-	-	-	-	-	-	-
MDCKOFAN_01181	1.44e-161	-	-	-	S	-	-	-	interspecies interaction between organisms
MDCKOFAN_01182	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
MDCKOFAN_01183	2.86e-13	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
MDCKOFAN_01184	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_01185	1.57e-84	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDCKOFAN_01186	5.61e-156	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MDCKOFAN_01187	1.03e-112	nanK	-	-	GK	-	-	-	ROK family
MDCKOFAN_01188	3.74e-70	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MDCKOFAN_01189	6.95e-165	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDCKOFAN_01190	6.48e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCKOFAN_01191	2.82e-84	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MDCKOFAN_01192	1.48e-28	axe1	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	acetyl xylan esterase
MDCKOFAN_01193	1.19e-141	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDCKOFAN_01194	1.1e-155	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDCKOFAN_01195	3.07e-136	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDCKOFAN_01196	7.93e-139	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDCKOFAN_01197	8.08e-160	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01198	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01199	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
MDCKOFAN_01200	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
MDCKOFAN_01201	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MDCKOFAN_01202	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
MDCKOFAN_01203	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MDCKOFAN_01204	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDCKOFAN_01206	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDCKOFAN_01208	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDCKOFAN_01209	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDCKOFAN_01210	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MDCKOFAN_01211	1.43e-186	-	-	-	K	-	-	-	SIS domain
MDCKOFAN_01212	9.6e-309	slpX	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01213	5.24e-31	-	-	-	S	-	-	-	transposase or invertase
MDCKOFAN_01214	1.48e-14	-	-	-	-	-	-	-	-
MDCKOFAN_01215	7.62e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MDCKOFAN_01218	0.0	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_01219	1.53e-232	-	-	-	-	-	-	-	-
MDCKOFAN_01220	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MDCKOFAN_01221	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MDCKOFAN_01222	4e-300	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDCKOFAN_01223	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MDCKOFAN_01224	6.73e-107	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_01225	2.55e-177	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_01227	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MDCKOFAN_01228	2.09e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MDCKOFAN_01229	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDCKOFAN_01230	2.76e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDCKOFAN_01231	1.13e-241	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
MDCKOFAN_01232	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDCKOFAN_01233	1.41e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDCKOFAN_01234	4.6e-291	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MDCKOFAN_01235	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MDCKOFAN_01236	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MDCKOFAN_01237	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_01238	8.83e-147	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MDCKOFAN_01239	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCKOFAN_01240	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
MDCKOFAN_01241	3.73e-240	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MDCKOFAN_01242	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MDCKOFAN_01243	7.74e-61	-	-	-	-	-	-	-	-
MDCKOFAN_01244	1.04e-48	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MDCKOFAN_01245	1.15e-155	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MDCKOFAN_01246	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDCKOFAN_01247	7.99e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MDCKOFAN_01248	1.74e-111	-	-	-	-	-	-	-	-
MDCKOFAN_01249	7.76e-98	-	-	-	-	-	-	-	-
MDCKOFAN_01250	1.45e-180	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MDCKOFAN_01251	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDCKOFAN_01252	8.42e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MDCKOFAN_01253	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MDCKOFAN_01254	2.6e-37	-	-	-	-	-	-	-	-
MDCKOFAN_01255	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MDCKOFAN_01256	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDCKOFAN_01257	4.25e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDCKOFAN_01258	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDCKOFAN_01259	6.73e-208	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MDCKOFAN_01260	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MDCKOFAN_01261	1.71e-143	-	-	-	S	-	-	-	CYTH
MDCKOFAN_01262	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MDCKOFAN_01263	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDCKOFAN_01264	9.29e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDCKOFAN_01265	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MDCKOFAN_01266	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
MDCKOFAN_01267	7.21e-140	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01268	6.39e-21	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01269	7.26e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01270	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MDCKOFAN_01271	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MDCKOFAN_01272	3.47e-164	-	-	-	-	-	-	-	-
MDCKOFAN_01273	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MDCKOFAN_01274	7.8e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MDCKOFAN_01275	1.2e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDCKOFAN_01276	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MDCKOFAN_01277	1.03e-275	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDCKOFAN_01278	3.47e-19	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
MDCKOFAN_01280	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MDCKOFAN_01281	6.51e-114	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_01282	1.02e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDCKOFAN_01283	3.92e-110	usp5	-	-	T	-	-	-	universal stress protein
MDCKOFAN_01285	1.57e-208	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MDCKOFAN_01286	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDCKOFAN_01287	4.7e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_01288	1.29e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_01289	1.21e-40	-	-	-	-	-	-	-	-
MDCKOFAN_01290	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MDCKOFAN_01291	6.77e-139	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01292	6.35e-28	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_01293	4.56e-191	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_01295	2.45e-65	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MDCKOFAN_01296	2.85e-54	-	-	-	-	-	-	-	-
MDCKOFAN_01298	7.39e-165	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01300	2.09e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDCKOFAN_01301	7.32e-232	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MDCKOFAN_01302	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MDCKOFAN_01303	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDCKOFAN_01304	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDCKOFAN_01305	1.98e-168	-	-	-	-	-	-	-	-
MDCKOFAN_01306	1.72e-149	-	-	-	-	-	-	-	-
MDCKOFAN_01307	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDCKOFAN_01308	3.61e-60	-	-	-	-	-	-	-	-
MDCKOFAN_01309	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDCKOFAN_01311	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDCKOFAN_01312	6.55e-97	-	-	-	-	-	-	-	-
MDCKOFAN_01313	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MDCKOFAN_01314	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDCKOFAN_01315	2.31e-277	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDCKOFAN_01316	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MDCKOFAN_01317	3.41e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MDCKOFAN_01318	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDCKOFAN_01319	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MDCKOFAN_01320	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MDCKOFAN_01321	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDCKOFAN_01322	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDCKOFAN_01323	2.47e-107	-	-	-	-	-	-	-	-
MDCKOFAN_01324	5.61e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MDCKOFAN_01325	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDCKOFAN_01326	6.08e-153	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MDCKOFAN_01327	3.12e-135	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MDCKOFAN_01328	1.68e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCKOFAN_01329	4.1e-193	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MDCKOFAN_01330	5.64e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDCKOFAN_01331	2.34e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDCKOFAN_01332	5.68e-34	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MDCKOFAN_01333	7.06e-102	yveB	-	-	I	-	-	-	PAP2 superfamily
MDCKOFAN_01334	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MDCKOFAN_01335	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
MDCKOFAN_01336	7.62e-223	-	-	-	-	-	-	-	-
MDCKOFAN_01337	7e-242	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MDCKOFAN_01338	5.95e-114	ymdB	-	-	S	-	-	-	Macro domain protein
MDCKOFAN_01344	1.31e-231	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MDCKOFAN_01345	2.43e-93	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDCKOFAN_01346	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDCKOFAN_01347	2.55e-223	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
MDCKOFAN_01348	1.39e-120	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MDCKOFAN_01349	4.92e-73	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
MDCKOFAN_01350	1.22e-157	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDCKOFAN_01351	2.28e-21	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_01352	1.18e-89	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_01353	4.07e-140	-	-	-	K	-	-	-	LysR family
MDCKOFAN_01354	0.0	-	-	-	C	-	-	-	FMN_bind
MDCKOFAN_01355	2.52e-140	-	-	-	K	-	-	-	LysR family
MDCKOFAN_01356	3.53e-287	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDCKOFAN_01357	0.0	-	-	-	C	-	-	-	FMN_bind
MDCKOFAN_01358	3.74e-180	-	-	-	L	-	-	-	Transposase DDE domain
MDCKOFAN_01359	2.37e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MDCKOFAN_01360	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MDCKOFAN_01361	3.76e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDCKOFAN_01362	2.68e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MDCKOFAN_01363	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MDCKOFAN_01364	6.07e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_01365	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MDCKOFAN_01366	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_01367	3.85e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MDCKOFAN_01368	3.7e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDCKOFAN_01369	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDCKOFAN_01370	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MDCKOFAN_01371	2.22e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MDCKOFAN_01372	5.96e-202	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDCKOFAN_01373	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDCKOFAN_01374	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MDCKOFAN_01375	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDCKOFAN_01376	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDCKOFAN_01377	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MDCKOFAN_01378	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MDCKOFAN_01379	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MDCKOFAN_01380	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDCKOFAN_01381	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDCKOFAN_01382	3.51e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MDCKOFAN_01383	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MDCKOFAN_01384	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MDCKOFAN_01385	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDCKOFAN_01386	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MDCKOFAN_01387	2.34e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01388	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MDCKOFAN_01389	1.39e-53	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDCKOFAN_01390	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDCKOFAN_01391	1.92e-212	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MDCKOFAN_01392	6.61e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDCKOFAN_01393	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MDCKOFAN_01394	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MDCKOFAN_01395	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDCKOFAN_01396	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDCKOFAN_01397	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MDCKOFAN_01398	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDCKOFAN_01399	3.65e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCKOFAN_01400	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MDCKOFAN_01401	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MDCKOFAN_01402	1.56e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_01405	2.99e-31	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
MDCKOFAN_01407	1.8e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01410	1.7e-23	-	-	-	-	-	-	-	-
MDCKOFAN_01411	2.87e-93	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
MDCKOFAN_01418	8.93e-33	-	-	-	S	-	-	-	HNH endonuclease
MDCKOFAN_01419	9.54e-88	-	-	-	S	-	-	-	AAA domain
MDCKOFAN_01421	4.6e-184	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDCKOFAN_01422	1e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MDCKOFAN_01423	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MDCKOFAN_01434	3.85e-49	-	-	-	S	-	-	-	VRR_NUC
MDCKOFAN_01438	1.71e-72	-	-	-	S	-	-	-	Phage terminase, small subunit
MDCKOFAN_01440	2.37e-263	-	-	-	S	-	-	-	Phage Terminase
MDCKOFAN_01442	4.25e-167	-	-	-	S	-	-	-	Phage portal protein
MDCKOFAN_01443	1.59e-110	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MDCKOFAN_01444	8.25e-69	-	-	-	S	-	-	-	Phage capsid family
MDCKOFAN_01452	2.31e-134	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDCKOFAN_01454	7.82e-158	-	-	-	S	-	-	-	Phage minor structural protein
MDCKOFAN_01463	5.77e-39	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MDCKOFAN_01464	4.97e-102	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MDCKOFAN_01465	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDCKOFAN_01466	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MDCKOFAN_01467	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDCKOFAN_01468	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDCKOFAN_01469	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MDCKOFAN_01470	1.21e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MDCKOFAN_01471	6.74e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MDCKOFAN_01472	7.97e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCKOFAN_01473	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDCKOFAN_01474	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDCKOFAN_01475	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDCKOFAN_01476	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDCKOFAN_01477	1.13e-41	-	-	-	M	-	-	-	Lysin motif
MDCKOFAN_01478	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MDCKOFAN_01479	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MDCKOFAN_01480	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MDCKOFAN_01481	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDCKOFAN_01482	2.06e-92	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MDCKOFAN_01483	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDCKOFAN_01484	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDCKOFAN_01485	3.47e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDCKOFAN_01486	2.04e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDCKOFAN_01487	9.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MDCKOFAN_01488	1.01e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDCKOFAN_01489	1.52e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDCKOFAN_01490	6.35e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDCKOFAN_01491	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDCKOFAN_01492	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
MDCKOFAN_01493	1.43e-19	-	-	-	K	-	-	-	FCD
MDCKOFAN_01494	1.45e-34	-	-	-	K	-	-	-	FCD
MDCKOFAN_01495	6.55e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDCKOFAN_01496	6.08e-148	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDCKOFAN_01497	7.07e-126	-	-	-	L	-	-	-	PFAM Integrase catalytic
MDCKOFAN_01498	1.72e-126	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01499	4.63e-32	-	-	-	-	-	-	-	-
MDCKOFAN_01500	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
MDCKOFAN_01501	8.28e-102	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
MDCKOFAN_01502	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
MDCKOFAN_01503	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_01504	2.8e-294	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MDCKOFAN_01505	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDCKOFAN_01506	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MDCKOFAN_01507	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MDCKOFAN_01508	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MDCKOFAN_01509	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MDCKOFAN_01510	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MDCKOFAN_01511	9.78e-216	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MDCKOFAN_01512	1.01e-22	-	-	-	L	-	-	-	Transposase
MDCKOFAN_01513	7.51e-16	-	-	-	L	-	-	-	Transposase
MDCKOFAN_01514	1.21e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDCKOFAN_01516	4.4e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDCKOFAN_01517	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MDCKOFAN_01518	4.57e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MDCKOFAN_01519	1.1e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDCKOFAN_01520	1.64e-99	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDCKOFAN_01521	6.59e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MDCKOFAN_01522	3.01e-210	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_01523	4.65e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDCKOFAN_01525	1.97e-315	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01526	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MDCKOFAN_01527	2.13e-167	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDCKOFAN_01528	1.29e-295	-	-	-	E	ko:K03294	-	ko00000	amino acid
MDCKOFAN_01529	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDCKOFAN_01530	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MDCKOFAN_01531	3.36e-112	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MDCKOFAN_01532	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDCKOFAN_01533	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDCKOFAN_01534	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MDCKOFAN_01535	2.14e-154	-	-	-	C	-	-	-	nitroreductase
MDCKOFAN_01536	1.76e-52	-	-	-	-	-	-	-	-
MDCKOFAN_01537	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDCKOFAN_01538	1.52e-103	-	-	-	-	-	-	-	-
MDCKOFAN_01539	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MDCKOFAN_01540	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MDCKOFAN_01541	8.61e-54	-	-	-	S	-	-	-	Enterocin A Immunity
MDCKOFAN_01542	1.71e-172	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
MDCKOFAN_01546	6.21e-60	-	-	-	V	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
MDCKOFAN_01547	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDCKOFAN_01548	1.64e-101	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MDCKOFAN_01549	1.72e-97	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MDCKOFAN_01552	2.02e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01553	9.66e-12	-	-	-	-	-	-	-	-
MDCKOFAN_01554	2.29e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MDCKOFAN_01555	3.98e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDCKOFAN_01557	2.34e-107	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01558	9.98e-91	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01560	2.29e-112	-	-	-	-	-	-	-	-
MDCKOFAN_01561	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDCKOFAN_01562	6.14e-233	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDCKOFAN_01563	2.94e-189	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDCKOFAN_01564	7.53e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MDCKOFAN_01565	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MDCKOFAN_01566	4.69e-158	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDCKOFAN_01567	5.02e-190	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_01569	2.7e-79	-	-	-	-	-	-	-	-
MDCKOFAN_01571	2.15e-253	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDCKOFAN_01572	5.46e-181	noxC	1.5.1.39	-	C	ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	coenzyme F420-1:gamma-L-glutamate ligase activity
MDCKOFAN_01573	1.45e-232	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDCKOFAN_01574	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDCKOFAN_01575	2.62e-176	-	-	-	-	-	-	-	-
MDCKOFAN_01576	4.34e-174	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01577	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
MDCKOFAN_01578	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDCKOFAN_01579	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDCKOFAN_01580	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDCKOFAN_01581	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
MDCKOFAN_01582	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MDCKOFAN_01583	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MDCKOFAN_01584	3.35e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDCKOFAN_01585	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDCKOFAN_01586	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDCKOFAN_01587	6.51e-247	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDCKOFAN_01588	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MDCKOFAN_01589	5.55e-80	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MDCKOFAN_01590	1.55e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MDCKOFAN_01591	3.85e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MDCKOFAN_01608	6.35e-90	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_01609	2.14e-45	-	-	-	V	-	-	-	Abi-like protein
MDCKOFAN_01612	5.63e-57	-	-	-	K	-	-	-	Peptidase S24-like
MDCKOFAN_01613	8.39e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01614	3.28e-144	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
MDCKOFAN_01620	3.84e-81	-	-	-	S	-	-	-	ERF superfamily
MDCKOFAN_01621	1.95e-71	-	-	-	S	-	-	-	calcium ion binding
MDCKOFAN_01622	5.39e-106	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MDCKOFAN_01636	1.29e-115	-	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_01637	7.7e-126	-	-	-	L	-	-	-	Helix-turn-helix domain
MDCKOFAN_01638	3.21e-175	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MDCKOFAN_01639	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDCKOFAN_01640	3.09e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MDCKOFAN_01641	5.62e-316	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MDCKOFAN_01642	3.04e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDCKOFAN_01643	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDCKOFAN_01644	2.24e-198	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDCKOFAN_01645	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDCKOFAN_01646	1.05e-40	-	-	-	-	-	-	-	-
MDCKOFAN_01647	2.25e-209	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_01648	1.26e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01650	5.98e-119	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_01651	1.26e-62	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_01652	7.1e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDCKOFAN_01653	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MDCKOFAN_01654	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MDCKOFAN_01655	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
MDCKOFAN_01656	0.0	yycH	-	-	S	-	-	-	YycH protein
MDCKOFAN_01657	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDCKOFAN_01658	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDCKOFAN_01660	1.09e-46	-	-	-	-	-	-	-	-
MDCKOFAN_01662	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
MDCKOFAN_01663	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MDCKOFAN_01664	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
MDCKOFAN_01665	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
MDCKOFAN_01666	3.92e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MDCKOFAN_01667	6.8e-50	-	-	-	S	-	-	-	Cytochrome B5
MDCKOFAN_01668	4.3e-175	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDCKOFAN_01669	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDCKOFAN_01670	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDCKOFAN_01671	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDCKOFAN_01672	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
MDCKOFAN_01673	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
MDCKOFAN_01674	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MDCKOFAN_01675	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDCKOFAN_01676	1.09e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDCKOFAN_01677	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDCKOFAN_01678	9e-190	-	-	-	-	-	-	-	-
MDCKOFAN_01679	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDCKOFAN_01680	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDCKOFAN_01681	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MDCKOFAN_01682	1.91e-24	-	-	-	D	-	-	-	GA module
MDCKOFAN_01683	1.89e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MDCKOFAN_01685	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MDCKOFAN_01686	6.18e-54	-	-	-	K	-	-	-	Helix-turn-helix
MDCKOFAN_01687	9.63e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDCKOFAN_01688	8.34e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MDCKOFAN_01689	6.38e-191	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MDCKOFAN_01690	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDCKOFAN_01691	1.69e-61	-	-	-	F	-	-	-	AAA domain
MDCKOFAN_01692	4.61e-104	-	-	-	K	-	-	-	acetyltransferase
MDCKOFAN_01693	6.58e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDCKOFAN_01694	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDCKOFAN_01695	2.38e-88	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDCKOFAN_01696	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MDCKOFAN_01697	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDCKOFAN_01698	3.56e-56	-	-	-	-	-	-	-	-
MDCKOFAN_01699	7.03e-216	-	-	-	GK	-	-	-	ROK family
MDCKOFAN_01700	8.39e-314	ptcC	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01701	2.3e-169	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDCKOFAN_01702	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDCKOFAN_01703	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDCKOFAN_01704	0.0	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01705	5.52e-113	-	-	-	-	-	-	-	-
MDCKOFAN_01706	5.17e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDCKOFAN_01707	5.03e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MDCKOFAN_01708	1.42e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MDCKOFAN_01709	1.57e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDCKOFAN_01710	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDCKOFAN_01711	1.11e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MDCKOFAN_01712	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDCKOFAN_01713	3.02e-49	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDCKOFAN_01714	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDCKOFAN_01715	4.37e-173	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDCKOFAN_01716	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MDCKOFAN_01717	1.5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MDCKOFAN_01718	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDCKOFAN_01719	1.66e-143	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MDCKOFAN_01721	1.67e-143	-	-	-	-	-	-	-	-
MDCKOFAN_01722	5.69e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDCKOFAN_01723	8.35e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDCKOFAN_01724	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MDCKOFAN_01725	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_01726	7.1e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDCKOFAN_01727	7.82e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCKOFAN_01728	5.46e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCKOFAN_01729	2.64e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDCKOFAN_01730	0.0	-	-	-	L	-	-	-	Transposase DDE domain
MDCKOFAN_01731	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_01732	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_01733	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDCKOFAN_01734	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MDCKOFAN_01736	9.39e-71	-	-	-	-	-	-	-	-
MDCKOFAN_01737	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDCKOFAN_01738	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MDCKOFAN_01739	5.02e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_01740	2.62e-166	-	-	-	F	-	-	-	glutamine amidotransferase
MDCKOFAN_01741	9.76e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MDCKOFAN_01742	1.8e-305	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MDCKOFAN_01743	6.41e-194	-	-	-	-	-	-	-	-
MDCKOFAN_01744	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
MDCKOFAN_01745	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MDCKOFAN_01746	4.37e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MDCKOFAN_01747	7.33e-59	-	-	-	-	-	-	-	-
MDCKOFAN_01748	5.43e-172	-	-	-	-	-	-	-	-
MDCKOFAN_01749	6.86e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MDCKOFAN_01750	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MDCKOFAN_01751	9.69e-184	-	-	-	P	-	-	-	Voltage gated chloride channel
MDCKOFAN_01752	3.44e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MDCKOFAN_01753	8.68e-69	-	-	-	-	-	-	-	-
MDCKOFAN_01754	1.17e-56	-	-	-	-	-	-	-	-
MDCKOFAN_01755	5.66e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDCKOFAN_01756	0.0	-	-	-	E	-	-	-	amino acid
MDCKOFAN_01757	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDCKOFAN_01758	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
MDCKOFAN_01759	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MDCKOFAN_01760	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDCKOFAN_01761	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDCKOFAN_01762	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDCKOFAN_01763	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDCKOFAN_01764	2.65e-197	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MDCKOFAN_01765	1.16e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDCKOFAN_01767	3.31e-185	lipA	-	-	I	-	-	-	Carboxylesterase family
MDCKOFAN_01768	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MDCKOFAN_01769	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_01770	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_01771	7.71e-188	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDCKOFAN_01772	4.3e-66	-	-	-	-	-	-	-	-
MDCKOFAN_01773	8.51e-50	-	-	-	-	-	-	-	-
MDCKOFAN_01774	2.1e-82	-	-	-	S	-	-	-	Alpha beta hydrolase
MDCKOFAN_01775	2.19e-49	-	-	-	S	-	-	-	Alpha beta hydrolase
MDCKOFAN_01776	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDCKOFAN_01777	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MDCKOFAN_01778	8.74e-62	-	-	-	-	-	-	-	-
MDCKOFAN_01779	8.94e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDCKOFAN_01780	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MDCKOFAN_01781	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDCKOFAN_01782	1.82e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDCKOFAN_01783	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MDCKOFAN_01784	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MDCKOFAN_01785	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MDCKOFAN_01786	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MDCKOFAN_01787	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
MDCKOFAN_01788	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MDCKOFAN_01789	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MDCKOFAN_01790	4.17e-65	-	-	-	S	-	-	-	Phospholipase, patatin family
MDCKOFAN_01792	2.32e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MDCKOFAN_01793	1.01e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDCKOFAN_01794	2.81e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MDCKOFAN_01795	1.31e-128	-	-	-	I	-	-	-	PAP2 superfamily
MDCKOFAN_01796	5e-227	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDCKOFAN_01798	4.35e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MDCKOFAN_01799	1.03e-34	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
MDCKOFAN_01800	6.34e-40	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
MDCKOFAN_01801	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MDCKOFAN_01802	4.22e-41	-	-	-	C	-	-	-	Heavy-metal-associated domain
MDCKOFAN_01803	1.45e-102	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MDCKOFAN_01804	2.6e-110	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MDCKOFAN_01805	1.85e-164	yobV3	-	-	K	-	-	-	WYL domain
MDCKOFAN_01806	5.61e-72	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
MDCKOFAN_01807	5.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MDCKOFAN_01808	1.07e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MDCKOFAN_01810	0.0	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_01811	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MDCKOFAN_01812	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MDCKOFAN_01813	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
MDCKOFAN_01814	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDCKOFAN_01815	2.08e-118	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MDCKOFAN_01816	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
MDCKOFAN_01818	8.77e-102	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDCKOFAN_01820	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
MDCKOFAN_01821	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
MDCKOFAN_01822	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDCKOFAN_01823	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MDCKOFAN_01824	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_01825	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDCKOFAN_01826	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDCKOFAN_01827	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDCKOFAN_01828	0.0	snf	-	-	KL	-	-	-	domain protein
MDCKOFAN_01829	3.24e-112	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MDCKOFAN_01830	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MDCKOFAN_01831	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MDCKOFAN_01832	1.73e-209	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDCKOFAN_01833	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MDCKOFAN_01834	4.35e-185	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MDCKOFAN_01835	6.69e-239	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDCKOFAN_01836	1.16e-208	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MDCKOFAN_01837	1.12e-136	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
MDCKOFAN_01838	2.34e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MDCKOFAN_01839	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
MDCKOFAN_01840	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MDCKOFAN_01841	6.12e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MDCKOFAN_01842	2.06e-298	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MDCKOFAN_01843	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDCKOFAN_01844	4.72e-134	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MDCKOFAN_01845	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MDCKOFAN_01846	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
MDCKOFAN_01847	9.97e-08	-	-	-	-	-	-	-	-
MDCKOFAN_01848	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
MDCKOFAN_01849	1.13e-126	-	-	-	-	-	-	-	-
MDCKOFAN_01850	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MDCKOFAN_01851	5.73e-153	-	-	-	-	-	-	-	-
MDCKOFAN_01852	1.71e-150	-	-	-	S	-	-	-	Peptidase family M23
MDCKOFAN_01853	6.57e-141	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDCKOFAN_01854	1.24e-125	-	-	-	M	-	-	-	hydrolase, family 25
MDCKOFAN_01855	3.09e-22	-	-	-	-	-	-	-	-
MDCKOFAN_01863	9.43e-300	-	-	-	S	-	-	-	Phage minor structural protein
MDCKOFAN_01865	7.81e-169	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MDCKOFAN_01866	8.34e-116	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01867	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDCKOFAN_01868	3.85e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDCKOFAN_01869	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDCKOFAN_01870	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDCKOFAN_01871	6.64e-94	-	-	-	-	-	-	-	-
MDCKOFAN_01872	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDCKOFAN_01873	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDCKOFAN_01874	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDCKOFAN_01875	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
MDCKOFAN_01876	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDCKOFAN_01877	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDCKOFAN_01878	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MDCKOFAN_01879	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MDCKOFAN_01880	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MDCKOFAN_01881	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDCKOFAN_01882	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDCKOFAN_01883	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01884	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
MDCKOFAN_01885	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDCKOFAN_01886	1.49e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MDCKOFAN_01887	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MDCKOFAN_01888	1.05e-67	-	-	-	-	-	-	-	-
MDCKOFAN_01889	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDCKOFAN_01890	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MDCKOFAN_01891	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MDCKOFAN_01892	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MDCKOFAN_01893	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MDCKOFAN_01894	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MDCKOFAN_01895	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
MDCKOFAN_01896	5.11e-265	-	-	-	S	-	-	-	Membrane
MDCKOFAN_01897	1.42e-58	-	-	-	-	-	-	-	-
MDCKOFAN_01898	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MDCKOFAN_01899	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCKOFAN_01900	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MDCKOFAN_01901	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCKOFAN_01902	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDCKOFAN_01903	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_01904	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MDCKOFAN_01905	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDCKOFAN_01906	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDCKOFAN_01907	1.96e-49	-	-	-	-	-	-	-	-
MDCKOFAN_01908	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01909	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01910	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_01911	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDCKOFAN_01912	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MDCKOFAN_01913	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDCKOFAN_01914	1.05e-309	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDCKOFAN_01915	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MDCKOFAN_01916	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
MDCKOFAN_01917	6.21e-116	-	-	-	V	-	-	-	HNH endonuclease
MDCKOFAN_01918	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDCKOFAN_01919	7.51e-205	-	-	-	-	-	-	-	-
MDCKOFAN_01920	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDCKOFAN_01921	2.73e-107	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MDCKOFAN_01922	2.71e-200	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MDCKOFAN_01923	1.52e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDCKOFAN_01924	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MDCKOFAN_01925	8.32e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDCKOFAN_01926	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDCKOFAN_01927	3.88e-52	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDCKOFAN_01928	5e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDCKOFAN_01929	4.55e-221	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDCKOFAN_01930	2.94e-166	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDCKOFAN_01931	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDCKOFAN_01932	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDCKOFAN_01933	4.55e-106	-	-	-	M	-	-	-	family 8
MDCKOFAN_01934	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDCKOFAN_01935	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDCKOFAN_01936	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MDCKOFAN_01937	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDCKOFAN_01938	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MDCKOFAN_01939	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDCKOFAN_01940	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MDCKOFAN_01941	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDCKOFAN_01942	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MDCKOFAN_01943	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDCKOFAN_01944	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MDCKOFAN_01945	4.59e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MDCKOFAN_01946	4.76e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDCKOFAN_01947	4.22e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MDCKOFAN_01948	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01949	7.42e-123	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_01950	8.69e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDCKOFAN_01951	1.19e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01952	1.24e-144	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
MDCKOFAN_01953	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
MDCKOFAN_01954	7.3e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MDCKOFAN_01955	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MDCKOFAN_01956	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_01957	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MDCKOFAN_01960	7.63e-43	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MDCKOFAN_01961	2.51e-52	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
MDCKOFAN_01962	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
MDCKOFAN_01963	1.56e-108	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01964	6.38e-154	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDCKOFAN_01965	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MDCKOFAN_01966	1.87e-58	-	-	-	-	-	-	-	-
MDCKOFAN_01967	9.46e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MDCKOFAN_01968	9.01e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDCKOFAN_01969	6.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MDCKOFAN_01970	2.13e-151	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MDCKOFAN_01971	6.95e-29	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MDCKOFAN_01972	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDCKOFAN_01973	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MDCKOFAN_01974	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MDCKOFAN_01975	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_01976	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDCKOFAN_01977	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDCKOFAN_01978	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDCKOFAN_01979	2.37e-242	-	-	-	T	-	-	-	GHKL domain
MDCKOFAN_01980	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MDCKOFAN_01981	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MDCKOFAN_01982	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_01983	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MDCKOFAN_01984	8.12e-60	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MDCKOFAN_01985	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MDCKOFAN_01986	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MDCKOFAN_01987	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDCKOFAN_01988	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MDCKOFAN_01989	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MDCKOFAN_01990	1.51e-154	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
MDCKOFAN_01991	1.24e-188	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
MDCKOFAN_01992	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MDCKOFAN_01993	8.8e-207	-	-	-	L	-	-	-	HNH nucleases
MDCKOFAN_01994	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MDCKOFAN_01995	2.59e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MDCKOFAN_01996	8.22e-240	-	-	-	M	-	-	-	Glycosyl transferase
MDCKOFAN_01997	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MDCKOFAN_01998	9.69e-25	-	-	-	-	-	-	-	-
MDCKOFAN_01999	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MDCKOFAN_02000	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MDCKOFAN_02001	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
MDCKOFAN_02002	6.78e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MDCKOFAN_02003	1.64e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MDCKOFAN_02004	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDCKOFAN_02005	1.23e-225	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MDCKOFAN_02006	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MDCKOFAN_02007	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MDCKOFAN_02008	5.76e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MDCKOFAN_02009	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDCKOFAN_02010	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MDCKOFAN_02011	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MDCKOFAN_02012	1.12e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDCKOFAN_02013	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MDCKOFAN_02014	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDCKOFAN_02015	3.85e-109	-	-	-	-	-	-	-	-
MDCKOFAN_02016	3.04e-53	-	-	-	C	-	-	-	FMN_bind
MDCKOFAN_02017	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MDCKOFAN_02018	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_02019	1.05e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDCKOFAN_02020	7.42e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDCKOFAN_02021	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDCKOFAN_02022	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDCKOFAN_02023	8.08e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDCKOFAN_02024	1.17e-103	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDCKOFAN_02025	5.27e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MDCKOFAN_02026	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MDCKOFAN_02027	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MDCKOFAN_02028	1.1e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDCKOFAN_02029	3.75e-135	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MDCKOFAN_02030	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDCKOFAN_02031	9.89e-74	-	-	-	-	-	-	-	-
MDCKOFAN_02032	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDCKOFAN_02033	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MDCKOFAN_02034	1.13e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDCKOFAN_02035	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDCKOFAN_02036	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MDCKOFAN_02037	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDCKOFAN_02038	9.26e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MDCKOFAN_02040	0.0	-	-	-	-	-	-	-	-
MDCKOFAN_02041	0.0	ycaM	-	-	E	-	-	-	amino acid
MDCKOFAN_02042	5.21e-181	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MDCKOFAN_02043	3.87e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MDCKOFAN_02044	3.8e-60	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDCKOFAN_02045	6.46e-119	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MDCKOFAN_02046	3.23e-149	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_02047	5.38e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MDCKOFAN_02048	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MDCKOFAN_02049	5.35e-121	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MDCKOFAN_02050	2.75e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MDCKOFAN_02051	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_02052	0.0	-	-	-	S	-	-	-	SH3-like domain
MDCKOFAN_02053	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDCKOFAN_02054	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MDCKOFAN_02055	1.61e-250	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MDCKOFAN_02056	8.18e-210	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MDCKOFAN_02057	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MDCKOFAN_02058	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDCKOFAN_02059	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDCKOFAN_02060	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDCKOFAN_02061	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDCKOFAN_02062	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MDCKOFAN_02063	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDCKOFAN_02064	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDCKOFAN_02065	8.33e-27	-	-	-	-	-	-	-	-
MDCKOFAN_02066	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDCKOFAN_02067	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDCKOFAN_02068	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDCKOFAN_02069	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MDCKOFAN_02070	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MDCKOFAN_02071	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MDCKOFAN_02072	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MDCKOFAN_02073	3.52e-292	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MDCKOFAN_02074	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDCKOFAN_02075	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDCKOFAN_02076	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MDCKOFAN_02077	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MDCKOFAN_02078	1.06e-298	ymfH	-	-	S	-	-	-	Peptidase M16
MDCKOFAN_02079	4.2e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MDCKOFAN_02080	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDCKOFAN_02081	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MDCKOFAN_02082	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDCKOFAN_02083	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MDCKOFAN_02084	2.32e-86	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MDCKOFAN_02085	2.9e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MDCKOFAN_02086	8.89e-57	sagB	-	-	C	-	-	-	Nitroreductase family
MDCKOFAN_02087	3.7e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MDCKOFAN_02088	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDCKOFAN_02089	2.45e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MDCKOFAN_02090	1.99e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDCKOFAN_02091	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDCKOFAN_02092	2.12e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDCKOFAN_02093	8.22e-270	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MDCKOFAN_02094	2.49e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MDCKOFAN_02095	0.0	-	-	-	L	-	-	-	Transposase
MDCKOFAN_02096	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MDCKOFAN_02097	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
MDCKOFAN_02098	1.09e-74	-	-	-	-	-	-	-	-
MDCKOFAN_02099	8.23e-112	-	-	-	-	-	-	-	-
MDCKOFAN_02100	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MDCKOFAN_02101	2.39e-182	-	-	-	S	-	-	-	DUF218 domain
MDCKOFAN_02102	1.06e-141	-	-	-	-	-	-	-	-
MDCKOFAN_02103	7.81e-107	-	-	-	-	-	-	-	-
MDCKOFAN_02104	1.28e-106	yicL	-	-	EG	-	-	-	EamA-like transporter family
MDCKOFAN_02105	6.7e-211	-	-	-	EG	-	-	-	EamA-like transporter family
MDCKOFAN_02106	5.7e-209	-	-	-	EG	-	-	-	EamA-like transporter family
MDCKOFAN_02107	2.52e-52	-	-	-	-	-	-	-	-
MDCKOFAN_02108	7.05e-146	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDCKOFAN_02109	2.72e-175	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDCKOFAN_02110	2.99e-196	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_02111	2.21e-315	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MDCKOFAN_02112	6.15e-34	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MDCKOFAN_02113	6.81e-64	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MDCKOFAN_02114	5.16e-118	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
MDCKOFAN_02115	2.55e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDCKOFAN_02116	9.29e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MDCKOFAN_02117	8.95e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDCKOFAN_02118	1.2e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDCKOFAN_02119	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MDCKOFAN_02120	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDCKOFAN_02121	1.36e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
MDCKOFAN_02122	1.05e-289	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MDCKOFAN_02123	1.77e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDCKOFAN_02124	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MDCKOFAN_02125	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MDCKOFAN_02127	7.92e-306	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDCKOFAN_02128	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDCKOFAN_02129	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MDCKOFAN_02130	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MDCKOFAN_02131	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MDCKOFAN_02132	9.23e-106	-	-	-	L	-	-	-	PFAM Transposase DDE domain
MDCKOFAN_02133	6.56e-118	-	-	-	V	-	-	-	ABC transporter transmembrane region
MDCKOFAN_02134	2.27e-179	-	-	-	-	-	-	-	-
MDCKOFAN_02138	1.95e-46	-	-	-	-	-	-	-	-
MDCKOFAN_02139	2.52e-76	-	-	-	S	-	-	-	Cupredoxin-like domain
MDCKOFAN_02140	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
MDCKOFAN_02141	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MDCKOFAN_02142	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MDCKOFAN_02143	7.41e-136	-	-	-	-	-	-	-	-
MDCKOFAN_02144	1.03e-65	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MDCKOFAN_02145	2.09e-110	-	-	-	-	-	-	-	-
MDCKOFAN_02147	5.06e-111	-	-	-	-	-	-	-	-
MDCKOFAN_02148	0.0	-	-	-	-	-	-	-	-
MDCKOFAN_02149	2.65e-107	-	-	-	S	-	-	-	Fic/DOC family
MDCKOFAN_02150	0.0	potE	-	-	E	-	-	-	Amino Acid
MDCKOFAN_02151	2.44e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDCKOFAN_02152	1.22e-310	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MDCKOFAN_02153	6.66e-41	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MDCKOFAN_02154	1.61e-70	-	-	-	-	-	-	-	-
MDCKOFAN_02155	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MDCKOFAN_02156	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDCKOFAN_02157	2.28e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDCKOFAN_02158	9.73e-254	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDCKOFAN_02159	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDCKOFAN_02160	4.04e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
MDCKOFAN_02161	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDCKOFAN_02162	5.73e-154	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MDCKOFAN_02163	1.8e-284	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCKOFAN_02164	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDCKOFAN_02165	1.22e-174	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MDCKOFAN_02166	1.17e-110	yfhC	-	-	C	-	-	-	nitroreductase
MDCKOFAN_02167	7.14e-115	-	-	-	-	-	-	-	-
MDCKOFAN_02169	5.36e-100	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDCKOFAN_02170	3.59e-69	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDCKOFAN_02171	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
MDCKOFAN_02172	1.38e-144	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MDCKOFAN_02173	7.51e-174	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDCKOFAN_02174	5.74e-69	-	-	-	-	-	-	-	-
MDCKOFAN_02175	3.7e-258	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MDCKOFAN_02176	7.94e-114	-	-	-	K	-	-	-	GNAT family
MDCKOFAN_02177	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDCKOFAN_02179	6.04e-49	-	-	-	-	-	-	-	-
MDCKOFAN_02180	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
MDCKOFAN_02181	8.44e-306	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
MDCKOFAN_02182	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MDCKOFAN_02183	3.53e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDCKOFAN_02184	5.55e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDCKOFAN_02185	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MDCKOFAN_02186	1.33e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MDCKOFAN_02187	4.37e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDCKOFAN_02188	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDCKOFAN_02189	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_02190	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDCKOFAN_02191	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDCKOFAN_02192	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDCKOFAN_02193	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDCKOFAN_02194	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
MDCKOFAN_02195	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDCKOFAN_02196	8.12e-195	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MDCKOFAN_02197	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MDCKOFAN_02198	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MDCKOFAN_02199	3.46e-212	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MDCKOFAN_02200	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MDCKOFAN_02201	7.19e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MDCKOFAN_02202	1.46e-31	-	-	-	-	-	-	-	-
MDCKOFAN_02203	3.51e-187	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MDCKOFAN_02204	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_02205	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MDCKOFAN_02206	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MDCKOFAN_02207	7.91e-14	-	-	-	-	-	-	-	-
MDCKOFAN_02208	2.93e-67	-	-	-	-	-	-	-	-
MDCKOFAN_02209	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
MDCKOFAN_02210	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDCKOFAN_02212	1.51e-44	-	-	-	-	-	-	-	-
MDCKOFAN_02213	7.7e-21	-	-	-	-	-	-	-	-
MDCKOFAN_02214	1.85e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDCKOFAN_02215	1.38e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MDCKOFAN_02216	6.77e-49	-	-	-	-	-	-	-	-
MDCKOFAN_02217	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDCKOFAN_02218	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDCKOFAN_02219	2.03e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDCKOFAN_02220	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDCKOFAN_02221	9.14e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDCKOFAN_02223	3.82e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDCKOFAN_02224	1.19e-43	-	-	-	S	-	-	-	reductase
MDCKOFAN_02225	2.98e-50	-	-	-	S	-	-	-	reductase
MDCKOFAN_02226	6.32e-41	-	-	-	S	-	-	-	reductase
MDCKOFAN_02227	1.77e-189	yxeH	-	-	S	-	-	-	hydrolase
MDCKOFAN_02228	1.98e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MDCKOFAN_02229	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_02230	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDCKOFAN_02231	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MDCKOFAN_02232	1.54e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MDCKOFAN_02233	9.4e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MDCKOFAN_02234	5.09e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MDCKOFAN_02235	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MDCKOFAN_02237	5.94e-100	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MDCKOFAN_02238	2.25e-57	-	-	-	K	-	-	-	Tetracycline repressor, C-terminal all-alpha domain
MDCKOFAN_02240	3.49e-113	-	-	-	K	-	-	-	LysR substrate binding domain
MDCKOFAN_02241	6.46e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MDCKOFAN_02242	1.17e-87	-	-	-	GM	-	-	-	NAD(P)H-binding
MDCKOFAN_02243	1.64e-169	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MDCKOFAN_02244	1.44e-62	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCKOFAN_02245	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MDCKOFAN_02246	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MDCKOFAN_02247	1.5e-90	-	-	-	-	-	-	-	-
MDCKOFAN_02248	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MDCKOFAN_02249	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDCKOFAN_02250	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDCKOFAN_02251	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDCKOFAN_02252	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MDCKOFAN_02253	3.87e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_02254	2.18e-122	yneE	-	-	K	-	-	-	Transcriptional regulator
MDCKOFAN_02255	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MDCKOFAN_02256	5.05e-11	-	-	-	-	-	-	-	-
MDCKOFAN_02257	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
MDCKOFAN_02258	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDCKOFAN_02259	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MDCKOFAN_02260	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MDCKOFAN_02261	9.48e-261	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDCKOFAN_02262	3.06e-53	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDCKOFAN_02264	2.18e-112	-	-	-	GKT	-	-	-	domain protein
MDCKOFAN_02265	0.0	-	3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
MDCKOFAN_02266	4.34e-198	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, fructose-specific IIC component
MDCKOFAN_02267	5.84e-50	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 9.98
MDCKOFAN_02268	2.4e-54	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDCKOFAN_02269	3.35e-101	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MDCKOFAN_02270	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MDCKOFAN_02271	8.05e-180	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MDCKOFAN_02272	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
MDCKOFAN_02273	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDCKOFAN_02274	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MDCKOFAN_02275	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_02276	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDCKOFAN_02278	8.25e-65	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MDCKOFAN_02279	9.75e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDCKOFAN_02281	3.5e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDCKOFAN_02282	4.04e-36	-	-	-	-	-	-	-	-
MDCKOFAN_02283	1.33e-72	-	-	-	-	-	-	-	-
MDCKOFAN_02284	1.74e-185	-	-	-	S	-	-	-	Replication initiation factor
MDCKOFAN_02285	2.14e-138	-	-	-	D	-	-	-	Ftsk spoiiie family protein
MDCKOFAN_02286	5.34e-77	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MDCKOFAN_02287	4.1e-34	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MDCKOFAN_02288	7.44e-129	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MDCKOFAN_02289	2.36e-157	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MDCKOFAN_02290	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDCKOFAN_02291	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MDCKOFAN_02292	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MDCKOFAN_02293	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDCKOFAN_02294	5.88e-278	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDCKOFAN_02295	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MDCKOFAN_02296	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDCKOFAN_02297	1.48e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDCKOFAN_02298	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MDCKOFAN_02299	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDCKOFAN_02300	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDCKOFAN_02301	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDCKOFAN_02302	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
MDCKOFAN_02303	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MDCKOFAN_02304	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MDCKOFAN_02305	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MDCKOFAN_02306	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDCKOFAN_02307	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDCKOFAN_02308	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MDCKOFAN_02309	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MDCKOFAN_02310	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDCKOFAN_02311	8.22e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDCKOFAN_02312	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MDCKOFAN_02313	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDCKOFAN_02314	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MDCKOFAN_02315	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MDCKOFAN_02316	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MDCKOFAN_02317	4.94e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MDCKOFAN_02318	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDCKOFAN_02319	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_02320	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDCKOFAN_02321	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MDCKOFAN_02322	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
MDCKOFAN_02323	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDCKOFAN_02324	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MDCKOFAN_02325	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MDCKOFAN_02326	4.96e-270	-	-	-	S	-	-	-	SLAP domain
MDCKOFAN_02327	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDCKOFAN_02328	1.63e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MDCKOFAN_02329	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDCKOFAN_02330	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MDCKOFAN_02331	2.32e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDCKOFAN_02332	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDCKOFAN_02333	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MDCKOFAN_02334	4.22e-185	-	-	-	M	-	-	-	Rib/alpha-like repeat
MDCKOFAN_02335	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDCKOFAN_02336	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDCKOFAN_02337	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MDCKOFAN_02338	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDCKOFAN_02339	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDCKOFAN_02340	2.05e-115	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MDCKOFAN_02341	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MDCKOFAN_02342	8.19e-116	-	-	-	G	-	-	-	Peptidase_C39 like family
MDCKOFAN_02343	9.23e-209	-	-	-	M	-	-	-	NlpC/P60 family
MDCKOFAN_02344	1.68e-44	-	-	-	G	-	-	-	Peptidase_C39 like family
MDCKOFAN_02345	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
MDCKOFAN_02346	9.78e-257	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDCKOFAN_02347	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDCKOFAN_02348	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MDCKOFAN_02350	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDCKOFAN_02351	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MDCKOFAN_02352	3.61e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MDCKOFAN_02353	1.91e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDCKOFAN_02354	1.32e-114	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDCKOFAN_02355	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MDCKOFAN_02356	4.46e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MDCKOFAN_02357	1.01e-116	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MDCKOFAN_02358	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDCKOFAN_02359	1.33e-165	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MDCKOFAN_02360	1.32e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDCKOFAN_02361	4.56e-78	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
MDCKOFAN_02362	2.72e-15	-	-	-	-	-	-	-	-
MDCKOFAN_02366	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MDCKOFAN_02367	2.36e-12	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
MDCKOFAN_02369	6.45e-93	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDCKOFAN_02370	1.05e-119	-	-	-	S	-	-	-	membrane
MDCKOFAN_02371	2.61e-23	-	-	-	-	-	-	-	-
MDCKOFAN_02372	3.58e-251	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MDCKOFAN_02373	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MDCKOFAN_02374	5.5e-155	-	-	-	-	-	-	-	-
MDCKOFAN_02375	1.2e-199	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MDCKOFAN_02376	1.05e-45	-	-	-	-	-	-	-	-
MDCKOFAN_02377	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MDCKOFAN_02378	1.66e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MDCKOFAN_02379	1.51e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDCKOFAN_02380	7.1e-136	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MDCKOFAN_02381	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MDCKOFAN_02382	3.46e-32	-	-	-	S	-	-	-	Alpha beta hydrolase
MDCKOFAN_02383	1.47e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDCKOFAN_02384	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MDCKOFAN_02385	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDCKOFAN_02386	3.07e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDCKOFAN_02387	0.0	-	-	-	L	-	-	-	Nuclease-related domain
MDCKOFAN_02388	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDCKOFAN_02389	2.31e-148	-	-	-	S	-	-	-	repeat protein
MDCKOFAN_02390	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MDCKOFAN_02391	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDCKOFAN_02392	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MDCKOFAN_02393	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDCKOFAN_02394	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDCKOFAN_02395	1.22e-55	-	-	-	-	-	-	-	-
MDCKOFAN_02396	4.26e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MDCKOFAN_02397	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MDCKOFAN_02398	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDCKOFAN_02399	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MDCKOFAN_02400	4.68e-191	ylmH	-	-	S	-	-	-	S4 domain protein
MDCKOFAN_02401	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MDCKOFAN_02402	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDCKOFAN_02403	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDCKOFAN_02404	1.54e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDCKOFAN_02405	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDCKOFAN_02406	1.65e-265	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDCKOFAN_02407	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDCKOFAN_02408	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDCKOFAN_02409	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDCKOFAN_02410	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MDCKOFAN_02411	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDCKOFAN_02412	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDCKOFAN_02413	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MDCKOFAN_02414	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MDCKOFAN_02415	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MDCKOFAN_02416	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MDCKOFAN_02417	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MDCKOFAN_02418	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MDCKOFAN_02419	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MDCKOFAN_02420	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MDCKOFAN_02421	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDCKOFAN_02422	2.91e-67	-	-	-	-	-	-	-	-
MDCKOFAN_02423	1.73e-165	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MDCKOFAN_02424	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDCKOFAN_02425	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_02426	2.09e-59	-	-	-	-	-	-	-	-
MDCKOFAN_02427	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MDCKOFAN_02428	1.73e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MDCKOFAN_02429	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
MDCKOFAN_02430	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDCKOFAN_02431	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDCKOFAN_02432	1.51e-123	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal