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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCAHIEPB_00001	3.13e-112	-	-	-	L	-	-	-	DNA integration
HCAHIEPB_00003	2.2e-59	-	-	-	S	-	-	-	SPP1 phage holin
HCAHIEPB_00004	1.62e-168	-	-	-	M	-	-	-	N-acetylmuramoyl-L-alanine amidase
HCAHIEPB_00005	2.52e-06	-	-	-	V	-	-	-	Ami_2
HCAHIEPB_00006	2.25e-28	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HCAHIEPB_00007	7.23e-161	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HCAHIEPB_00008	5e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
HCAHIEPB_00009	1.09e-34	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HCAHIEPB_00010	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HCAHIEPB_00011	4.87e-163	-	-	-	L	-	-	-	NUDIX domain
HCAHIEPB_00012	1.89e-226	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HCAHIEPB_00013	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCAHIEPB_00014	1.77e-168	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HCAHIEPB_00016	6.48e-142	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HCAHIEPB_00017	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HCAHIEPB_00018	2.2e-227	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HCAHIEPB_00019	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCAHIEPB_00020	9.58e-138	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCAHIEPB_00021	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HCAHIEPB_00022	6.48e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCAHIEPB_00023	9.16e-265	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HCAHIEPB_00024	1.29e-206	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00025	7.76e-175	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HCAHIEPB_00026	2.52e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCAHIEPB_00027	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HCAHIEPB_00028	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCAHIEPB_00029	3.51e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HCAHIEPB_00030	1.43e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCAHIEPB_00031	9.12e-159	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HCAHIEPB_00032	2.92e-190	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HCAHIEPB_00033	1.23e-100	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HCAHIEPB_00034	0.0	-	-	-	-	-	-	-	-
HCAHIEPB_00035	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HCAHIEPB_00036	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HCAHIEPB_00037	1.6e-306	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HCAHIEPB_00038	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HCAHIEPB_00039	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HCAHIEPB_00040	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCAHIEPB_00041	7.18e-194	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HCAHIEPB_00042	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCAHIEPB_00043	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HCAHIEPB_00044	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HCAHIEPB_00045	1.16e-121	-	-	-	-	-	-	-	-
HCAHIEPB_00046	0.000853	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00047	4.54e-17	int8	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00048	2.92e-79	int8	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00049	1.83e-06	int8	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00055	6.67e-44	-	-	-	-	-	-	-	-
HCAHIEPB_00056	2.07e-11	-	-	-	-	-	-	-	-
HCAHIEPB_00057	1.37e-149	-	-	-	K	-	-	-	Fic/DOC family
HCAHIEPB_00058	1.02e-07	-	-	-	-	-	-	-	-
HCAHIEPB_00059	5.05e-169	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_00060	1.61e-65	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_00061	1.29e-185	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_00062	6.48e-300	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HCAHIEPB_00063	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HCAHIEPB_00064	3.7e-166	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
HCAHIEPB_00065	1.1e-160	-	-	-	P	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00066	2.95e-266	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00067	4.34e-79	-	-	-	L	-	-	-	Resolvase, N terminal domain
HCAHIEPB_00069	1.64e-55	-	-	-	L	-	-	-	Transposase, Mutator family
HCAHIEPB_00070	2.01e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_00071	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00072	4.08e-117	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCAHIEPB_00073	5.21e-103	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCAHIEPB_00074	4.26e-91	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HCAHIEPB_00077	1.71e-09	-	-	-	-	-	-	-	-
HCAHIEPB_00078	1.49e-104	-	-	-	-	-	-	-	-
HCAHIEPB_00079	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HCAHIEPB_00080	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HCAHIEPB_00082	2.46e-113	-	-	-	-	-	-	-	-
HCAHIEPB_00083	5.54e-146	-	-	-	-	-	-	-	-
HCAHIEPB_00084	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCAHIEPB_00085	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCAHIEPB_00086	1.41e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_00087	1.35e-87	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_00088	2.57e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HCAHIEPB_00089	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HCAHIEPB_00090	3.74e-13	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HCAHIEPB_00091	4.74e-224	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HCAHIEPB_00092	2.61e-80	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HCAHIEPB_00093	1.42e-28	-	-	-	-	-	-	-	-
HCAHIEPB_00094	8.24e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HCAHIEPB_00095	2.23e-259	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HCAHIEPB_00096	2.1e-137	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCAHIEPB_00097	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HCAHIEPB_00098	5.48e-84	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HCAHIEPB_00099	1.33e-270	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HCAHIEPB_00100	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCAHIEPB_00101	1.58e-207	-	-	-	P	-	-	-	Cation efflux family
HCAHIEPB_00102	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCAHIEPB_00103	1.69e-172	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HCAHIEPB_00104	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HCAHIEPB_00105	9.42e-95	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
HCAHIEPB_00106	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
HCAHIEPB_00107	1.66e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HCAHIEPB_00108	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HCAHIEPB_00109	6.09e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCAHIEPB_00110	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HCAHIEPB_00111	1.59e-150	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HCAHIEPB_00112	3.24e-159	-	-	-	-	-	-	-	-
HCAHIEPB_00113	9.97e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCAHIEPB_00114	2.31e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HCAHIEPB_00115	7.62e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HCAHIEPB_00116	7.41e-102	-	-	-	K	-	-	-	MerR, DNA binding
HCAHIEPB_00117	5.52e-152	-	-	-	-	-	-	-	-
HCAHIEPB_00118	9.45e-317	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCAHIEPB_00119	3.84e-186	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCAHIEPB_00120	4.4e-171	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCAHIEPB_00121	2.67e-226	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HCAHIEPB_00124	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HCAHIEPB_00125	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00126	2.93e-42	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_00127	1.72e-58	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HCAHIEPB_00128	1.62e-44	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HCAHIEPB_00129	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HCAHIEPB_00130	2.92e-38	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HCAHIEPB_00131	1.02e-201	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HCAHIEPB_00132	3.41e-190	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HCAHIEPB_00133	5.26e-84	-	-	-	P	-	-	-	Rhodanese Homology Domain
HCAHIEPB_00134	6.92e-133	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCAHIEPB_00135	1.26e-169	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HCAHIEPB_00136	1.13e-276	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HCAHIEPB_00137	1.88e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HCAHIEPB_00138	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCAHIEPB_00139	1.06e-282	-	-	-	L	-	-	-	Tetratricopeptide repeat
HCAHIEPB_00140	4.84e-257	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HCAHIEPB_00142	1.28e-179	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HCAHIEPB_00143	1.59e-143	-	-	-	-	-	-	-	-
HCAHIEPB_00144	5.33e-89	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HCAHIEPB_00146	1.57e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCAHIEPB_00147	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HCAHIEPB_00148	2.23e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HCAHIEPB_00149	1.37e-17	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00150	3.33e-24	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00151	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HCAHIEPB_00152	6.07e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00153	1.12e-141	-	-	-	S	-	-	-	ABC-2 family transporter protein
HCAHIEPB_00154	2.3e-131	-	-	-	S	-	-	-	ABC-2 family transporter protein
HCAHIEPB_00155	7.19e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_00156	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HCAHIEPB_00157	1.15e-300	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCAHIEPB_00158	2.28e-127	-	-	-	-	-	-	-	-
HCAHIEPB_00159	1.1e-177	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCAHIEPB_00160	2.08e-115	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HCAHIEPB_00161	1.05e-30	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HCAHIEPB_00162	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HCAHIEPB_00163	6.43e-119	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HCAHIEPB_00164	4.23e-147	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCAHIEPB_00165	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCAHIEPB_00166	7.72e-229	-	-	-	C	-	-	-	Aldo/keto reductase family
HCAHIEPB_00167	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCAHIEPB_00168	4.64e-114	-	-	-	D	-	-	-	Septum formation initiator
HCAHIEPB_00169	1.13e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HCAHIEPB_00170	9.07e-234	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HCAHIEPB_00172	6.38e-259	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HCAHIEPB_00173	2.26e-246	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00174	7.05e-290	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCAHIEPB_00175	6.1e-76	-	-	-	L	-	-	-	HTH-like domain
HCAHIEPB_00176	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00177	1e-246	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_00178	0.0	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
HCAHIEPB_00179	7.6e-213	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HCAHIEPB_00180	6.38e-182	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HCAHIEPB_00181	6.72e-302	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCAHIEPB_00182	2.1e-152	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HCAHIEPB_00183	4.2e-185	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HCAHIEPB_00184	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HCAHIEPB_00185	2.12e-277	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HCAHIEPB_00186	8.82e-141	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HCAHIEPB_00187	1.58e-259	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00188	1.1e-296	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HCAHIEPB_00189	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HCAHIEPB_00190	3.97e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_00191	3.16e-170	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
HCAHIEPB_00192	1.42e-271	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HCAHIEPB_00193	3.88e-239	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_00195	3.1e-246	-	-	-	S	-	-	-	EpsG family
HCAHIEPB_00196	3.91e-246	-	-	-	G	-	-	-	Acyltransferase family
HCAHIEPB_00198	2.82e-193	-	-	-	L	-	-	-	IstB-like ATP binding protein
HCAHIEPB_00199	9.28e-58	-	-	-	L	-	-	-	Transposase
HCAHIEPB_00202	2.03e-22	-	-	-	M	-	-	-	Collagen triple helix repeat (20 copies)
HCAHIEPB_00203	3.57e-17	-	-	-	-	-	-	-	-
HCAHIEPB_00204	3.98e-74	-	-	-	-	-	-	-	-
HCAHIEPB_00207	1.51e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_00208	5.28e-76	-	-	-	-	-	-	-	-
HCAHIEPB_00209	1.13e-156	-	-	-	S	-	-	-	phage tail tape measure protein
HCAHIEPB_00210	2.6e-45	-	-	-	-	-	-	-	-
HCAHIEPB_00211	1.97e-147	-	-	-	N	-	-	-	domain, Protein
HCAHIEPB_00212	5.09e-66	-	-	-	-	-	-	-	-
HCAHIEPB_00213	6.98e-29	-	-	-	-	-	-	-	-
HCAHIEPB_00214	1.35e-58	-	-	-	-	-	-	-	-
HCAHIEPB_00215	4.41e-68	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HCAHIEPB_00216	6.56e-05	-	-	-	-	-	-	-	-
HCAHIEPB_00217	2.77e-173	-	-	-	V	-	-	-	Phage capsid family
HCAHIEPB_00218	3.59e-72	-	-	-	-	-	-	-	-
HCAHIEPB_00220	3.44e-109	-	-	-	-	-	-	-	-
HCAHIEPB_00221	4.59e-264	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HCAHIEPB_00222	2.81e-220	-	-	-	S	-	-	-	Terminase
HCAHIEPB_00224	3.04e-57	-	-	-	V	-	-	-	HNH nucleases
HCAHIEPB_00226	3.74e-121	-	-	-	J	-	-	-	tRNA 5'-leader removal
HCAHIEPB_00232	3.28e-44	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HCAHIEPB_00234	5.22e-54	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
HCAHIEPB_00237	6.82e-47	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HCAHIEPB_00238	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00240	4.28e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCAHIEPB_00241	3.25e-223	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCAHIEPB_00242	7.82e-204	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCAHIEPB_00243	5.57e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_00244	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HCAHIEPB_00245	3.67e-47	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HCAHIEPB_00246	3.25e-29	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HCAHIEPB_00247	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HCAHIEPB_00248	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00249	2.11e-219	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HCAHIEPB_00250	1.16e-243	-	-	-	I	-	-	-	Acyltransferase family
HCAHIEPB_00251	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
HCAHIEPB_00252	2.72e-316	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HCAHIEPB_00253	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
HCAHIEPB_00254	0.0	-	-	-	L	-	-	-	Transposase
HCAHIEPB_00256	2.15e-192	-	-	-	S	-	-	-	KAP family P-loop domain
HCAHIEPB_00257	9.01e-95	-	-	-	S	-	-	-	KAP family P-loop domain
HCAHIEPB_00259	3.11e-31	-	-	-	-	-	-	-	-
HCAHIEPB_00260	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HCAHIEPB_00261	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_00262	1.51e-146	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_00263	3.79e-76	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HCAHIEPB_00264	8.84e-74	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HCAHIEPB_00265	4.44e-45	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HCAHIEPB_00266	1.18e-27	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HCAHIEPB_00267	1.21e-243	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_00268	6.58e-154	-	-	-	-	-	-	-	-
HCAHIEPB_00269	1.29e-91	xylR	-	-	GK	-	-	-	ROK family
HCAHIEPB_00270	7.81e-211	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HCAHIEPB_00271	3.96e-100	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HCAHIEPB_00272	8.91e-145	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
HCAHIEPB_00273	2.84e-95	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
HCAHIEPB_00274	1.12e-71	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
HCAHIEPB_00275	9.88e-57	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
HCAHIEPB_00276	2.7e-296	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HCAHIEPB_00277	8.45e-217	-	-	-	-	-	-	-	-
HCAHIEPB_00278	9.71e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HCAHIEPB_00279	7.26e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HCAHIEPB_00280	9.45e-208	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HCAHIEPB_00281	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCAHIEPB_00283	2.38e-277	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCAHIEPB_00284	2.57e-274	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HCAHIEPB_00285	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCAHIEPB_00286	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCAHIEPB_00287	8.49e-66	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00288	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
HCAHIEPB_00289	4.9e-176	-	-	-	-	-	-	-	-
HCAHIEPB_00290	3.27e-315	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HCAHIEPB_00291	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCAHIEPB_00292	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCAHIEPB_00293	1.95e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HCAHIEPB_00294	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCAHIEPB_00295	6.62e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCAHIEPB_00296	3.36e-19	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HCAHIEPB_00298	4.34e-282	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HCAHIEPB_00299	1.87e-168	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00300	1.23e-134	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HCAHIEPB_00301	1.55e-178	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00302	3.01e-155	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00303	1.07e-200	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HCAHIEPB_00304	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HCAHIEPB_00305	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCAHIEPB_00306	1.63e-281	-	-	-	G	-	-	-	Transmembrane secretion effector
HCAHIEPB_00307	4.49e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_00308	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HCAHIEPB_00309	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCAHIEPB_00310	3.11e-72	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCAHIEPB_00311	1.44e-65	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCAHIEPB_00312	1.59e-303	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HCAHIEPB_00313	1.01e-234	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCAHIEPB_00314	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HCAHIEPB_00315	4.05e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCAHIEPB_00316	3.47e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HCAHIEPB_00317	8.7e-178	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00318	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HCAHIEPB_00319	4.75e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HCAHIEPB_00320	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HCAHIEPB_00321	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HCAHIEPB_00322	1.93e-270	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HCAHIEPB_00323	1.64e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
HCAHIEPB_00324	6.01e-214	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HCAHIEPB_00325	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HCAHIEPB_00326	2.45e-293	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HCAHIEPB_00327	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HCAHIEPB_00328	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HCAHIEPB_00329	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HCAHIEPB_00330	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCAHIEPB_00331	1.93e-252	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCAHIEPB_00332	3.07e-301	-	-	-	G	-	-	-	polysaccharide deacetylase
HCAHIEPB_00333	4.8e-293	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HCAHIEPB_00335	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCAHIEPB_00336	1.83e-172	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HCAHIEPB_00337	5e-96	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCAHIEPB_00338	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCAHIEPB_00339	3.74e-211	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HCAHIEPB_00340	0.0	-	-	-	-	-	-	-	-
HCAHIEPB_00341	1.35e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HCAHIEPB_00342	1.94e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HCAHIEPB_00343	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HCAHIEPB_00344	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HCAHIEPB_00346	4.39e-72	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HCAHIEPB_00347	3.07e-20	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
HCAHIEPB_00351	8.33e-80	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HCAHIEPB_00352	3.04e-32	-	-	-	-	-	-	-	-
HCAHIEPB_00353	6.01e-246	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCAHIEPB_00354	1.67e-34	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
HCAHIEPB_00355	8.44e-71	-	-	-	L	-	-	-	RelB antitoxin
HCAHIEPB_00356	1.05e-88	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HCAHIEPB_00357	4.27e-148	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCAHIEPB_00358	4.38e-303	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HCAHIEPB_00359	6.54e-250	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HCAHIEPB_00360	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HCAHIEPB_00361	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HCAHIEPB_00362	4.75e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HCAHIEPB_00363	1.44e-226	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HCAHIEPB_00364	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HCAHIEPB_00365	8.66e-254	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HCAHIEPB_00366	3.28e-194	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCAHIEPB_00367	4.85e-159	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCAHIEPB_00368	2.17e-121	-	-	-	D	-	-	-	nuclear chromosome segregation
HCAHIEPB_00369	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HCAHIEPB_00370	9.77e-279	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HCAHIEPB_00371	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HCAHIEPB_00372	2.11e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCAHIEPB_00373	9.26e-306	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HCAHIEPB_00374	3.14e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HCAHIEPB_00375	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HCAHIEPB_00376	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HCAHIEPB_00377	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HCAHIEPB_00378	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HCAHIEPB_00379	4.51e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCAHIEPB_00380	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HCAHIEPB_00381	2.8e-186	-	-	-	S	-	-	-	alpha beta
HCAHIEPB_00382	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCAHIEPB_00383	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCAHIEPB_00384	4.41e-283	-	-	-	T	-	-	-	Forkhead associated domain
HCAHIEPB_00385	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HCAHIEPB_00386	8.23e-39	-	-	-	-	-	-	-	-
HCAHIEPB_00387	5.63e-137	-	-	-	NO	-	-	-	SAF
HCAHIEPB_00388	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
HCAHIEPB_00389	1.03e-78	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HCAHIEPB_00390	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCAHIEPB_00391	1.32e-183	-	-	-	-	-	-	-	-
HCAHIEPB_00392	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCAHIEPB_00396	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HCAHIEPB_00397	2.87e-288	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HCAHIEPB_00398	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HCAHIEPB_00399	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HCAHIEPB_00400	8.83e-286	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HCAHIEPB_00401	1.65e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCAHIEPB_00402	1.46e-28	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HCAHIEPB_00403	1.25e-81	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HCAHIEPB_00405	2.08e-30	-	-	-	-	-	-	-	-
HCAHIEPB_00406	7.41e-277	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_00407	2.69e-312	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00408	2.42e-208	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00409	7.21e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00410	4.71e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HCAHIEPB_00411	1.04e-147	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HCAHIEPB_00412	1.22e-235	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCAHIEPB_00413	6.88e-144	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HCAHIEPB_00414	9.47e-152	-	-	-	-	-	-	-	-
HCAHIEPB_00415	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HCAHIEPB_00416	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCAHIEPB_00417	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HCAHIEPB_00418	5.93e-10	-	-	-	L	-	-	-	Helix-turn-helix domain
HCAHIEPB_00419	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HCAHIEPB_00420	2.24e-285	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HCAHIEPB_00421	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HCAHIEPB_00422	8.47e-184	-	-	-	S	-	-	-	YwiC-like protein
HCAHIEPB_00423	3.82e-176	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HCAHIEPB_00424	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HCAHIEPB_00425	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCAHIEPB_00426	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HCAHIEPB_00427	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCAHIEPB_00428	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCAHIEPB_00429	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCAHIEPB_00430	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCAHIEPB_00431	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCAHIEPB_00432	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCAHIEPB_00433	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HCAHIEPB_00434	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCAHIEPB_00435	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCAHIEPB_00436	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCAHIEPB_00437	1.95e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCAHIEPB_00438	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCAHIEPB_00439	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCAHIEPB_00440	1.33e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCAHIEPB_00441	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCAHIEPB_00442	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCAHIEPB_00443	3.26e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HCAHIEPB_00444	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HCAHIEPB_00445	9.34e-317	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCAHIEPB_00446	2.57e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCAHIEPB_00447	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCAHIEPB_00448	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HCAHIEPB_00449	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCAHIEPB_00450	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCAHIEPB_00451	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCAHIEPB_00452	2.44e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCAHIEPB_00453	1.27e-218	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCAHIEPB_00454	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HCAHIEPB_00455	5.93e-194	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HCAHIEPB_00457	6.91e-124	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_00458	1.13e-161	-	-	-	-	-	-	-	-
HCAHIEPB_00459	1.3e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HCAHIEPB_00460	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCAHIEPB_00461	3.5e-107	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCAHIEPB_00462	2.13e-277	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCAHIEPB_00463	7.14e-279	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HCAHIEPB_00464	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCAHIEPB_00465	4.12e-133	-	-	-	-	-	-	-	-
HCAHIEPB_00466	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HCAHIEPB_00467	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCAHIEPB_00468	3.7e-240	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCAHIEPB_00469	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HCAHIEPB_00470	1.23e-96	-	-	-	K	-	-	-	Transcriptional regulator
HCAHIEPB_00471	2.57e-251	-	-	-	S	-	-	-	Protein conserved in bacteria
HCAHIEPB_00472	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HCAHIEPB_00473	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HCAHIEPB_00474	2.63e-208	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HCAHIEPB_00475	1.08e-269	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HCAHIEPB_00476	2.27e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCAHIEPB_00478	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00479	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00480	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HCAHIEPB_00481	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HCAHIEPB_00482	1.7e-261	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HCAHIEPB_00483	2.18e-224	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCAHIEPB_00484	1.01e-152	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_00485	2.84e-301	tcsS3	-	-	KT	-	-	-	PspC domain
HCAHIEPB_00486	0.0	pspC	-	-	KT	-	-	-	PspC domain
HCAHIEPB_00487	8.93e-97	-	-	-	-	-	-	-	-
HCAHIEPB_00488	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HCAHIEPB_00489	4.35e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HCAHIEPB_00490	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HCAHIEPB_00491	4.86e-279	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HCAHIEPB_00493	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HCAHIEPB_00494	3.23e-221	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HCAHIEPB_00495	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCAHIEPB_00496	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HCAHIEPB_00497	1.12e-239	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCAHIEPB_00498	6.59e-44	-	-	-	-	-	-	-	-
HCAHIEPB_00499	2.76e-269	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCAHIEPB_00500	2.08e-216	-	-	-	S	-	-	-	CHAP domain
HCAHIEPB_00501	1.45e-138	-	-	-	M	-	-	-	NlpC/P60 family
HCAHIEPB_00502	3.11e-142	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HCAHIEPB_00503	1.36e-241	-	-	-	T	-	-	-	Universal stress protein family
HCAHIEPB_00504	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
HCAHIEPB_00505	1.73e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCAHIEPB_00506	1.07e-164	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HCAHIEPB_00507	1.22e-126	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HCAHIEPB_00508	9.79e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_00509	1.94e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HCAHIEPB_00510	2.53e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCAHIEPB_00511	5.94e-09	-	-	-	L	-	-	-	Integrase core domain
HCAHIEPB_00512	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HCAHIEPB_00514	1.98e-280	-	-	-	GK	-	-	-	ROK family
HCAHIEPB_00515	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00516	1.65e-27	-	-	-	L	-	-	-	Helix-turn-helix domain
HCAHIEPB_00517	2.41e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCAHIEPB_00518	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00519	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HCAHIEPB_00520	4.42e-19	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00522	9.16e-211	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCAHIEPB_00525	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HCAHIEPB_00526	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HCAHIEPB_00527	1.09e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_00528	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HCAHIEPB_00529	5.04e-298	-	-	-	M	-	-	-	Glycosyl transferase family 21
HCAHIEPB_00530	1.36e-244	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00531	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HCAHIEPB_00532	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HCAHIEPB_00533	4.76e-268	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCAHIEPB_00534	1.08e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCAHIEPB_00535	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCAHIEPB_00536	1.9e-153	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HCAHIEPB_00537	2.85e-207	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCAHIEPB_00538	1.37e-288	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCAHIEPB_00539	3.27e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HCAHIEPB_00540	8.55e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HCAHIEPB_00541	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HCAHIEPB_00542	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00544	8.67e-228	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_00545	4e-117	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HCAHIEPB_00546	6.22e-21	-	-	-	EGP	-	-	-	Major facilitator superfamily
HCAHIEPB_00547	5.53e-207	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HCAHIEPB_00548	7.76e-89	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCAHIEPB_00549	2.4e-187	-	-	-	-	-	-	-	-
HCAHIEPB_00550	9.08e-135	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HCAHIEPB_00552	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HCAHIEPB_00553	1.22e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCAHIEPB_00554	2.17e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCAHIEPB_00555	4.61e-272	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HCAHIEPB_00556	1.08e-196	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCAHIEPB_00557	6.2e-241	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCAHIEPB_00558	4.72e-206	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HCAHIEPB_00559	3.38e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00560	2.92e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HCAHIEPB_00561	1.44e-276	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HCAHIEPB_00562	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCAHIEPB_00563	3.86e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HCAHIEPB_00564	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HCAHIEPB_00565	1.39e-195	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HCAHIEPB_00566	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCAHIEPB_00567	7.68e-151	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HCAHIEPB_00568	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HCAHIEPB_00569	2.91e-199	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HCAHIEPB_00570	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HCAHIEPB_00571	9.67e-317	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HCAHIEPB_00572	3.56e-218	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HCAHIEPB_00573	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00574	1.5e-129	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00575	1.24e-114	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HCAHIEPB_00576	2.14e-257	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HCAHIEPB_00577	3.16e-299	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HCAHIEPB_00578	8.34e-229	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HCAHIEPB_00579	1.21e-268	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HCAHIEPB_00581	1.28e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HCAHIEPB_00582	3.3e-85	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCAHIEPB_00583	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HCAHIEPB_00584	7.97e-117	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
HCAHIEPB_00585	1.7e-55	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCAHIEPB_00586	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCAHIEPB_00587	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HCAHIEPB_00588	1.89e-173	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCAHIEPB_00589	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HCAHIEPB_00590	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HCAHIEPB_00591	5.17e-153	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HCAHIEPB_00592	2.71e-227	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein, family 5
HCAHIEPB_00593	1.09e-248	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HCAHIEPB_00595	1.4e-14	-	-	-	K	ko:K02855,ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko03000	sequence-specific DNA binding
HCAHIEPB_00596	1.02e-73	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_00597	5.03e-237	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein, family 5
HCAHIEPB_00598	2.73e-141	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00599	2.79e-142	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCAHIEPB_00600	4.83e-187	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00601	2.72e-160	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HCAHIEPB_00602	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HCAHIEPB_00603	1.67e-49	-	-	-	S	-	-	-	PIN domain
HCAHIEPB_00604	1.65e-31	-	-	-	K	-	-	-	Antidote-toxin recognition MazE, bacterial antitoxin
HCAHIEPB_00605	7.51e-89	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HCAHIEPB_00606	9.04e-24	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_00608	1.57e-64	-	-	-	K	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCAHIEPB_00609	1.8e-261	-	-	-	G	-	-	-	Transporter major facilitator family protein
HCAHIEPB_00610	1.06e-101	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_00611	2.19e-308	-	-	-	S	-	-	-	Protein of unknown function (DUF4038)
HCAHIEPB_00612	1.84e-256	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HCAHIEPB_00613	7.12e-62	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HCAHIEPB_00614	7.61e-93	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HCAHIEPB_00615	1.63e-269	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HCAHIEPB_00616	1.97e-110	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_00617	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HCAHIEPB_00618	1.23e-117	-	-	-	K	-	-	-	MarR family
HCAHIEPB_00619	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_00620	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HCAHIEPB_00621	0.0	-	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCAHIEPB_00622	2.16e-133	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HCAHIEPB_00623	2.1e-180	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCAHIEPB_00624	3.16e-194	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00625	7.8e-197	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00626	1.33e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HCAHIEPB_00627	1.01e-227	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HCAHIEPB_00628	5.76e-243	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HCAHIEPB_00629	1.51e-168	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCAHIEPB_00630	5.37e-290	bdhA	-	-	C	ko:K19955	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
HCAHIEPB_00631	6.69e-208	rbsK	2.7.1.15	-	G	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCAHIEPB_00632	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HCAHIEPB_00633	2.95e-49	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_00634	1.11e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_00635	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00636	4.24e-211	rbsC	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HCAHIEPB_00637	8.68e-207	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HCAHIEPB_00638	3e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	RbsD / FucU transport protein family
HCAHIEPB_00639	9.72e-229	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCAHIEPB_00640	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCAHIEPB_00641	2.77e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCAHIEPB_00642	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCAHIEPB_00643	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HCAHIEPB_00644	2.61e-235	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCAHIEPB_00645	5.05e-170	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCAHIEPB_00646	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCAHIEPB_00647	1.43e-154	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HCAHIEPB_00648	2.05e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
HCAHIEPB_00649	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HCAHIEPB_00650	3.44e-131	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCAHIEPB_00651	1.16e-165	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HCAHIEPB_00652	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HCAHIEPB_00653	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HCAHIEPB_00654	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HCAHIEPB_00655	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HCAHIEPB_00656	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HCAHIEPB_00657	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HCAHIEPB_00658	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HCAHIEPB_00659	3.68e-144	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HCAHIEPB_00660	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HCAHIEPB_00661	8.64e-76	-	-	-	-	-	-	-	-
HCAHIEPB_00662	1.27e-214	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HCAHIEPB_00663	5.53e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HCAHIEPB_00664	3.26e-119	-	-	-	-	-	-	-	-
HCAHIEPB_00665	1.62e-209	-	-	-	S	-	-	-	Protein of unknown function DUF58
HCAHIEPB_00666	1.53e-245	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HCAHIEPB_00667	1.4e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCAHIEPB_00668	1.18e-126	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HCAHIEPB_00669	1.54e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HCAHIEPB_00670	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCAHIEPB_00671	6.57e-54	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HCAHIEPB_00672	2.67e-148	-	-	-	-	-	-	-	-
HCAHIEPB_00673	1.44e-169	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HCAHIEPB_00674	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCAHIEPB_00675	5.87e-86	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HCAHIEPB_00676	4.74e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HCAHIEPB_00677	3.99e-231	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCAHIEPB_00678	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HCAHIEPB_00679	2.13e-15	-	-	-	K	-	-	-	AraC-like ligand binding domain
HCAHIEPB_00680	1.63e-177	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HCAHIEPB_00681	2.35e-67	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HCAHIEPB_00682	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HCAHIEPB_00683	8.64e-317	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HCAHIEPB_00684	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HCAHIEPB_00685	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCAHIEPB_00686	3.02e-130	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HCAHIEPB_00687	7.77e-197	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HCAHIEPB_00688	3.16e-189	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HCAHIEPB_00689	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00690	1.27e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00691	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HCAHIEPB_00692	1.88e-144	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HCAHIEPB_00693	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HCAHIEPB_00695	2.54e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HCAHIEPB_00696	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HCAHIEPB_00697	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HCAHIEPB_00699	6.11e-25	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HCAHIEPB_00700	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00701	4.03e-239	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCAHIEPB_00702	1.59e-67	-	-	-	-	-	-	-	-
HCAHIEPB_00703	1e-71	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HCAHIEPB_00704	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HCAHIEPB_00705	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_00706	4.04e-134	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCAHIEPB_00707	1.55e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HCAHIEPB_00708	8.77e-193	-	-	-	C	-	-	-	Putative TM nitroreductase
HCAHIEPB_00709	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_00710	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HCAHIEPB_00711	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HCAHIEPB_00712	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_00713	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
HCAHIEPB_00714	8.19e-244	-	-	-	-	-	-	-	-
HCAHIEPB_00715	8.31e-158	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_00716	6.21e-292	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_00717	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HCAHIEPB_00718	1.64e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HCAHIEPB_00719	6.39e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCAHIEPB_00720	2.76e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HCAHIEPB_00721	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HCAHIEPB_00722	4.54e-197	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCAHIEPB_00723	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HCAHIEPB_00724	0.0	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCAHIEPB_00725	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCAHIEPB_00726	7.01e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCAHIEPB_00727	3.44e-60	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HCAHIEPB_00728	1.2e-89	-	-	-	V	-	-	-	DivIVA protein
HCAHIEPB_00729	1.72e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCAHIEPB_00730	4.29e-227	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCAHIEPB_00731	6.11e-256	-	-	-	K	-	-	-	WYL domain
HCAHIEPB_00732	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HCAHIEPB_00734	8.89e-214	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
HCAHIEPB_00735	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HCAHIEPB_00736	1.14e-170	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00739	9.86e-211	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HCAHIEPB_00740	2.8e-186	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HCAHIEPB_00741	5.06e-194	-	-	-	S	-	-	-	Amidohydrolase
HCAHIEPB_00742	2.86e-212	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HCAHIEPB_00743	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HCAHIEPB_00744	3.87e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
HCAHIEPB_00745	1.7e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
HCAHIEPB_00746	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCAHIEPB_00747	3.03e-277	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCAHIEPB_00748	1.66e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HCAHIEPB_00749	7.57e-163	-	-	-	-	-	-	-	-
HCAHIEPB_00750	8.43e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCAHIEPB_00751	7.13e-169	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HCAHIEPB_00752	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HCAHIEPB_00753	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCAHIEPB_00754	1.3e-281	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HCAHIEPB_00755	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HCAHIEPB_00756	1.99e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HCAHIEPB_00757	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCAHIEPB_00758	1.61e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCAHIEPB_00759	2.3e-206	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCAHIEPB_00760	3.03e-168	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCAHIEPB_00761	7.41e-70	-	-	-	M	-	-	-	Lysin motif
HCAHIEPB_00762	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCAHIEPB_00763	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCAHIEPB_00764	0.0	-	-	-	L	-	-	-	DNA helicase
HCAHIEPB_00765	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCAHIEPB_00766	2e-241	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCAHIEPB_00767	2.23e-91	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HCAHIEPB_00768	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HCAHIEPB_00769	2.6e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCAHIEPB_00770	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCAHIEPB_00771	3.33e-265	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCAHIEPB_00772	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCAHIEPB_00773	2.45e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HCAHIEPB_00774	1.02e-277	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCAHIEPB_00775	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HCAHIEPB_00776	8.3e-231	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HCAHIEPB_00778	1.87e-107	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCAHIEPB_00779	1.19e-123	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00780	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HCAHIEPB_00781	1.31e-287	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_00782	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_00783	1.59e-266	-	-	-	GK	-	-	-	ROK family
HCAHIEPB_00784	1.15e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCAHIEPB_00785	3.53e-314	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HCAHIEPB_00786	1.58e-127	-	-	-	F	-	-	-	NUDIX domain
HCAHIEPB_00787	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HCAHIEPB_00788	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HCAHIEPB_00789	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HCAHIEPB_00790	2.08e-89	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00791	7.89e-245	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00792	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCAHIEPB_00793	1.11e-176	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HCAHIEPB_00794	3.96e-69	-	-	-	-	-	-	-	-
HCAHIEPB_00795	1.64e-240	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HCAHIEPB_00796	1.41e-243	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HCAHIEPB_00797	5.06e-234	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCAHIEPB_00798	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCAHIEPB_00799	1.23e-252	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCAHIEPB_00800	7.74e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HCAHIEPB_00801	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCAHIEPB_00802	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HCAHIEPB_00803	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCAHIEPB_00804	7.67e-114	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HCAHIEPB_00805	1.32e-206	-	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HCAHIEPB_00806	7.46e-245	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HCAHIEPB_00807	1.42e-201	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HCAHIEPB_00808	2.4e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HCAHIEPB_00809	9.39e-195	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCAHIEPB_00810	1.81e-149	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCAHIEPB_00811	3.89e-205	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HCAHIEPB_00812	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HCAHIEPB_00813	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HCAHIEPB_00814	2.16e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HCAHIEPB_00815	2.1e-305	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HCAHIEPB_00816	4.83e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HCAHIEPB_00817	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_00818	5.21e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00819	2.95e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
HCAHIEPB_00820	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HCAHIEPB_00821	2.23e-102	-	-	-	-	-	-	-	-
HCAHIEPB_00822	3.21e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HCAHIEPB_00823	2.35e-243	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HCAHIEPB_00824	2.36e-56	-	-	-	-	-	-	-	-
HCAHIEPB_00825	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCAHIEPB_00826	7.44e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_00827	5.73e-240	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HCAHIEPB_00828	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HCAHIEPB_00829	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00830	2.81e-233	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HCAHIEPB_00831	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HCAHIEPB_00832	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HCAHIEPB_00833	2.93e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HCAHIEPB_00834	2.99e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HCAHIEPB_00835	1.31e-306	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCAHIEPB_00836	1.52e-126	-	-	-	-	-	-	-	-
HCAHIEPB_00837	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HCAHIEPB_00838	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCAHIEPB_00839	2.33e-155	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_00840	5.17e-142	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_00841	2.83e-175	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCAHIEPB_00842	8.8e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HCAHIEPB_00843	1.99e-192	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HCAHIEPB_00844	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCAHIEPB_00845	7.74e-232	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCAHIEPB_00846	9.15e-192	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HCAHIEPB_00847	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HCAHIEPB_00848	5.95e-153	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCAHIEPB_00849	5.61e-127	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HCAHIEPB_00850	1.39e-102	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCAHIEPB_00851	9.3e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HCAHIEPB_00852	1.29e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCAHIEPB_00853	2.62e-132	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HCAHIEPB_00854	6.14e-155	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCAHIEPB_00855	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCAHIEPB_00856	4.78e-248	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCAHIEPB_00857	1.33e-158	-	-	-	-	-	-	-	-
HCAHIEPB_00858	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HCAHIEPB_00859	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HCAHIEPB_00860	5.84e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCAHIEPB_00861	6.88e-146	-	-	-	-	-	-	-	-
HCAHIEPB_00862	1.24e-248	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCAHIEPB_00863	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HCAHIEPB_00864	2.17e-285	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00865	1.73e-220	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCAHIEPB_00866	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HCAHIEPB_00870	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HCAHIEPB_00871	2e-296	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HCAHIEPB_00872	1.51e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HCAHIEPB_00873	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HCAHIEPB_00874	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HCAHIEPB_00875	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCAHIEPB_00876	4.67e-132	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCAHIEPB_00877	1.31e-98	-	-	-	-	-	-	-	-
HCAHIEPB_00879	0.0	-	-	-	S	-	-	-	HipA-like C-terminal domain
HCAHIEPB_00880	9.93e-220	-	-	-	S	-	-	-	Fic/DOC family
HCAHIEPB_00881	2.79e-53	-	-	-	-	-	-	-	-
HCAHIEPB_00882	3.13e-19	intA	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00883	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HCAHIEPB_00884	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HCAHIEPB_00885	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HCAHIEPB_00886	1.01e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_00887	4.6e-221	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00888	8.4e-199	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_00889	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HCAHIEPB_00890	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HCAHIEPB_00891	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HCAHIEPB_00892	2.66e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_00893	6.16e-301	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HCAHIEPB_00894	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HCAHIEPB_00895	2.26e-41	-	-	-	-	-	-	-	-
HCAHIEPB_00896	6.15e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
HCAHIEPB_00897	3.5e-220	-	-	-	EG	-	-	-	EamA-like transporter family
HCAHIEPB_00898	2.35e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HCAHIEPB_00899	2.98e-296	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HCAHIEPB_00900	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HCAHIEPB_00901	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCAHIEPB_00902	2.62e-206	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HCAHIEPB_00903	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HCAHIEPB_00904	1.75e-145	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HCAHIEPB_00905	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HCAHIEPB_00906	2.06e-220	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HCAHIEPB_00907	2.49e-111	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HCAHIEPB_00908	1.45e-203	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HCAHIEPB_00909	6.98e-137	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HCAHIEPB_00910	2.66e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCAHIEPB_00912	1.49e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_00913	9.59e-305	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_00915	4.19e-95	-	-	-	-	-	-	-	-
HCAHIEPB_00916	4.89e-183	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HCAHIEPB_00917	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HCAHIEPB_00918	3.13e-252	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCAHIEPB_00919	8.22e-173	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
HCAHIEPB_00920	3.03e-184	-	-	-	S	-	-	-	Fic/DOC family
HCAHIEPB_00922	4.72e-44	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_00924	2.35e-47	-	-	-	M	-	-	-	Peptidase family M23
HCAHIEPB_00925	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HCAHIEPB_00926	8.16e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HCAHIEPB_00927	8.81e-264	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HCAHIEPB_00928	5.83e-120	-	-	-	-	-	-	-	-
HCAHIEPB_00929	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HCAHIEPB_00930	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCAHIEPB_00931	2.69e-192	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HCAHIEPB_00932	7.92e-187	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCAHIEPB_00933	3.81e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HCAHIEPB_00934	4.97e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCAHIEPB_00935	8.23e-223	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HCAHIEPB_00936	1.36e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCAHIEPB_00937	1.61e-91	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HCAHIEPB_00938	4.13e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCAHIEPB_00939	2.28e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCAHIEPB_00940	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCAHIEPB_00941	5.16e-84	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HCAHIEPB_00942	9.65e-227	-	-	-	-	-	-	-	-
HCAHIEPB_00943	5.87e-99	-	-	-	-	-	-	-	-
HCAHIEPB_00944	5.5e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HCAHIEPB_00945	5.32e-11	-	-	-	-	-	-	-	-
HCAHIEPB_00946	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HCAHIEPB_00947	1.77e-27	-	-	-	G	-	-	-	Major facilitator Superfamily
HCAHIEPB_00948	5.41e-52	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00950	6.89e-63	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	kinase activity
HCAHIEPB_00951	2.36e-61	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HCAHIEPB_00952	3.98e-143	-	-	-	-	-	-	-	-
HCAHIEPB_00953	1.31e-32	-	-	-	-	-	-	-	-
HCAHIEPB_00955	2.23e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00956	3.51e-165	-	-	-	-	-	-	-	-
HCAHIEPB_00957	5.85e-133	-	-	-	-	-	-	-	-
HCAHIEPB_00958	2.76e-191	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HCAHIEPB_00959	3.95e-82	-	-	-	-	-	-	-	-
HCAHIEPB_00960	3.5e-93	-	-	-	-	-	-	-	-
HCAHIEPB_00961	2.73e-207	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HCAHIEPB_00962	2.87e-173	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HCAHIEPB_00963	3.55e-139	-	-	-	-	-	-	-	-
HCAHIEPB_00965	6.57e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HCAHIEPB_00967	8.87e-66	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HCAHIEPB_00968	1.27e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HCAHIEPB_00969	7.81e-235	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCAHIEPB_00970	7.99e-119	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_00971	2.91e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCAHIEPB_00972	5.1e-125	-	-	-	-	-	-	-	-
HCAHIEPB_00973	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_00974	3.3e-261	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_00975	6.56e-19	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_00978	1.39e-155	-	-	-	-	-	-	-	-
HCAHIEPB_00979	1.5e-65	-	-	-	-	-	-	-	-
HCAHIEPB_00980	1.1e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_00981	7.7e-81	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
HCAHIEPB_00982	2.96e-241	-	-	-	V	-	-	-	VanZ like family
HCAHIEPB_00983	4.07e-76	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_00984	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HCAHIEPB_00985	3.3e-200	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCAHIEPB_00986	3.05e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HCAHIEPB_00987	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCAHIEPB_00988	7.23e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCAHIEPB_00989	5.51e-240	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCAHIEPB_00990	7.16e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HCAHIEPB_00991	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HCAHIEPB_00992	3.05e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HCAHIEPB_00993	6.65e-138	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCAHIEPB_00994	7.29e-220	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HCAHIEPB_00995	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HCAHIEPB_00996	2.17e-179	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HCAHIEPB_00997	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HCAHIEPB_00998	3.04e-141	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCAHIEPB_00999	4.37e-84	-	-	-	-	-	-	-	-
HCAHIEPB_01000	2.44e-50	-	-	-	-	-	-	-	-
HCAHIEPB_01001	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HCAHIEPB_01002	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HCAHIEPB_01003	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HCAHIEPB_01004	4.22e-70	-	-	-	-	-	-	-	-
HCAHIEPB_01005	0.0	-	-	-	K	-	-	-	WYL domain
HCAHIEPB_01006	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCAHIEPB_01007	4.56e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCAHIEPB_01009	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HCAHIEPB_01010	1.57e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCAHIEPB_01011	1.55e-12	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCAHIEPB_01012	9.59e-154	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCAHIEPB_01013	2.5e-43	-	-	-	-	-	-	-	-
HCAHIEPB_01014	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HCAHIEPB_01015	1.39e-296	-	-	-	-	-	-	-	-
HCAHIEPB_01016	3.07e-210	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCAHIEPB_01017	1.2e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCAHIEPB_01018	5.54e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCAHIEPB_01019	5.33e-73	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HCAHIEPB_01020	1.82e-255	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCAHIEPB_01021	5.04e-139	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCAHIEPB_01022	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HCAHIEPB_01023	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HCAHIEPB_01024	3.78e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
HCAHIEPB_01025	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCAHIEPB_01031	4.38e-169	-	-	-	S	-	-	-	PAC2 family
HCAHIEPB_01032	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCAHIEPB_01033	7.54e-200	-	-	-	G	-	-	-	Fructosamine kinase
HCAHIEPB_01034	2.29e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCAHIEPB_01035	4.92e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCAHIEPB_01036	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HCAHIEPB_01037	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCAHIEPB_01038	3.05e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCAHIEPB_01039	7.19e-248	-	-	-	-	-	-	-	-
HCAHIEPB_01040	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HCAHIEPB_01041	6.7e-204	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCAHIEPB_01042	4.81e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCAHIEPB_01043	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HCAHIEPB_01044	1.7e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCAHIEPB_01045	1.02e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HCAHIEPB_01046	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HCAHIEPB_01047	5.67e-231	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HCAHIEPB_01048	8.83e-242	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HCAHIEPB_01049	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCAHIEPB_01050	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCAHIEPB_01051	1.43e-296	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01052	2.22e-41	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCAHIEPB_01053	9.21e-64	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCAHIEPB_01054	6.73e-76	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCAHIEPB_01055	6.87e-72	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCAHIEPB_01056	6.37e-169	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCAHIEPB_01057	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HCAHIEPB_01058	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCAHIEPB_01059	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCAHIEPB_01060	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HCAHIEPB_01061	3.01e-275	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01062	8.87e-39	-	-	-	-	-	-	-	-
HCAHIEPB_01063	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCAHIEPB_01064	4.86e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCAHIEPB_01065	2.25e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HCAHIEPB_01066	6.06e-224	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HCAHIEPB_01067	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCAHIEPB_01068	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HCAHIEPB_01069	5.17e-228	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HCAHIEPB_01070	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HCAHIEPB_01071	1.2e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCAHIEPB_01072	9.57e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HCAHIEPB_01073	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCAHIEPB_01075	1.38e-127	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HCAHIEPB_01076	4.3e-255	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HCAHIEPB_01077	1.45e-170	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HCAHIEPB_01079	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCAHIEPB_01080	1.99e-187	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HCAHIEPB_01081	1.16e-118	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HCAHIEPB_01082	1.68e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCAHIEPB_01083	2.82e-31	-	-	-	L	-	-	-	Transposase, Mutator family
HCAHIEPB_01084	1.04e-182	-	-	-	-	-	-	-	-
HCAHIEPB_01085	1.47e-136	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HCAHIEPB_01088	2.06e-49	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
HCAHIEPB_01089	8.54e-32	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01090	3.24e-24	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01091	8.33e-38	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_01092	4.88e-261	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01093	2.4e-201	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01094	2.92e-206	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01095	2.94e-261	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCAHIEPB_01096	1.78e-204	-	-	-	I	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCAHIEPB_01098	8.84e-12	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HCAHIEPB_01099	1.61e-73	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HCAHIEPB_01100	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01101	5.19e-222	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
HCAHIEPB_01102	7.15e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_01103	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCAHIEPB_01104	3.64e-204	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
HCAHIEPB_01105	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCAHIEPB_01106	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01107	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HCAHIEPB_01108	2.91e-189	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01109	2.23e-232	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HCAHIEPB_01110	3.69e-190	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCAHIEPB_01111	9.97e-18	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HCAHIEPB_01112	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HCAHIEPB_01113	1.32e-306	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_01114	6.61e-195	-	-	-	K	-	-	-	FCD
HCAHIEPB_01115	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCAHIEPB_01116	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCAHIEPB_01117	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HCAHIEPB_01118	4.93e-222	-	-	-	I	-	-	-	PAP2 superfamily
HCAHIEPB_01119	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCAHIEPB_01120	5.84e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCAHIEPB_01121	2.63e-265	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCAHIEPB_01122	1.5e-136	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01123	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HCAHIEPB_01125	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCAHIEPB_01128	1.52e-137	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HCAHIEPB_01129	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HCAHIEPB_01130	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HCAHIEPB_01131	9.13e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HCAHIEPB_01132	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
HCAHIEPB_01133	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_01134	2.06e-157	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HCAHIEPB_01135	1.73e-205	-	-	-	-	-	-	-	-
HCAHIEPB_01136	2.47e-296	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HCAHIEPB_01137	1.03e-240	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HCAHIEPB_01139	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCAHIEPB_01142	8.81e-103	-	-	-	-	-	-	-	-
HCAHIEPB_01143	5.06e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HCAHIEPB_01144	8.36e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCAHIEPB_01145	5.28e-105	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HCAHIEPB_01146	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HCAHIEPB_01147	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_01148	0.0	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
HCAHIEPB_01149	0.0	-	-	-	H	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HCAHIEPB_01150	2.15e-146	-	-	-	K	-	-	-	WHG domain
HCAHIEPB_01151	2.04e-142	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
HCAHIEPB_01152	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCAHIEPB_01153	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HCAHIEPB_01154	1.98e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_01155	2.3e-276	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HCAHIEPB_01156	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HCAHIEPB_01157	5.04e-76	-	-	-	U	-	-	-	TadE-like protein
HCAHIEPB_01158	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HCAHIEPB_01159	6.89e-151	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HCAHIEPB_01160	7.27e-95	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HCAHIEPB_01161	1.31e-245	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HCAHIEPB_01162	6.43e-160	-	-	-	D	-	-	-	bacterial-type flagellum organization
HCAHIEPB_01163	9.04e-172	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HCAHIEPB_01164	3.86e-164	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HCAHIEPB_01165	7.9e-182	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HCAHIEPB_01166	7.79e-142	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HCAHIEPB_01167	5.43e-21	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HCAHIEPB_01168	5.76e-134	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HCAHIEPB_01169	2.45e-224	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HCAHIEPB_01170	5.28e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCAHIEPB_01171	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HCAHIEPB_01172	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HCAHIEPB_01173	2.27e-247	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01174	8.38e-190	traX	-	-	S	-	-	-	TraX protein
HCAHIEPB_01175	9.93e-213	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01176	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01177	2.41e-299	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01178	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HCAHIEPB_01179	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HCAHIEPB_01180	5.58e-221	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HCAHIEPB_01181	0.0	-	-	-	M	-	-	-	domain protein
HCAHIEPB_01182	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
HCAHIEPB_01183	2.24e-239	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01184	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HCAHIEPB_01185	2.92e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCAHIEPB_01186	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCAHIEPB_01187	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HCAHIEPB_01188	1.03e-243	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01189	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HCAHIEPB_01190	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HCAHIEPB_01192	2.31e-255	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01193	1.8e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCAHIEPB_01194	3.82e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCAHIEPB_01195	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HCAHIEPB_01196	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCAHIEPB_01197	6.59e-254	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HCAHIEPB_01198	1.55e-223	-	-	-	EG	-	-	-	EamA-like transporter family
HCAHIEPB_01200	6.72e-218	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HCAHIEPB_01201	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HCAHIEPB_01202	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HCAHIEPB_01203	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HCAHIEPB_01204	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCAHIEPB_01206	1.49e-192	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HCAHIEPB_01207	1.01e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
HCAHIEPB_01208	9.5e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HCAHIEPB_01209	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HCAHIEPB_01210	2.82e-210	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_01211	7.68e-252	-	-	-	S	-	-	-	Fic/DOC family
HCAHIEPB_01212	7.13e-169	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HCAHIEPB_01213	1.82e-256	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCAHIEPB_01214	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HCAHIEPB_01215	0.0	-	-	-	S	-	-	-	Putative esterase
HCAHIEPB_01216	4.51e-36	-	-	-	-	-	-	-	-
HCAHIEPB_01217	2.2e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HCAHIEPB_01218	1.79e-112	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HCAHIEPB_01219	1.86e-271	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HCAHIEPB_01220	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HCAHIEPB_01221	8.7e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HCAHIEPB_01222	2.56e-104	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HCAHIEPB_01223	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HCAHIEPB_01224	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCAHIEPB_01225	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HCAHIEPB_01226	5.61e-224	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HCAHIEPB_01227	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HCAHIEPB_01228	7.81e-155	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HCAHIEPB_01229	9.28e-291	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HCAHIEPB_01230	1.56e-162	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HCAHIEPB_01231	2.41e-101	crgA	-	-	D	-	-	-	Involved in cell division
HCAHIEPB_01232	5.93e-179	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HCAHIEPB_01233	1.46e-47	-	-	-	-	-	-	-	-
HCAHIEPB_01234	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCAHIEPB_01235	1.75e-93	-	-	-	I	-	-	-	Sterol carrier protein
HCAHIEPB_01236	6.16e-289	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCAHIEPB_01237	2.26e-266	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_01238	2.66e-146	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCAHIEPB_01239	1.79e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HCAHIEPB_01240	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCAHIEPB_01241	0.0	-	-	-	S	-	-	-	Amidohydrolase family
HCAHIEPB_01242	3.07e-239	-	-	-	S	-	-	-	Protein conserved in bacteria
HCAHIEPB_01243	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCAHIEPB_01244	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCAHIEPB_01245	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HCAHIEPB_01246	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HCAHIEPB_01247	4.29e-160	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HCAHIEPB_01248	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HCAHIEPB_01249	2.97e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HCAHIEPB_01250	1.16e-200	-	-	-	P	-	-	-	VTC domain
HCAHIEPB_01251	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HCAHIEPB_01252	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HCAHIEPB_01253	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HCAHIEPB_01254	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HCAHIEPB_01255	5.5e-209	-	-	-	-	-	-	-	-
HCAHIEPB_01256	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HCAHIEPB_01257	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HCAHIEPB_01258	1.68e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HCAHIEPB_01259	3.52e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HCAHIEPB_01260	8.47e-264	-	-	-	S	-	-	-	AAA ATPase domain
HCAHIEPB_01261	9.82e-298	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HCAHIEPB_01262	2.21e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCAHIEPB_01263	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01264	5.95e-240	-	-	-	K	ko:K05499	-	ko00000,ko03000	Periplasmic binding protein-like domain
HCAHIEPB_01265	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01266	5.07e-293	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HCAHIEPB_01268	4.38e-147	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01269	1.28e-95	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01270	1.1e-91	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01271	2.79e-38	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01272	1.1e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01273	3.16e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCAHIEPB_01274	7.96e-93	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HCAHIEPB_01275	8.25e-63	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HCAHIEPB_01276	2.65e-185	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HCAHIEPB_01277	3.78e-271	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_01278	2.43e-240	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01279	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HCAHIEPB_01280	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01281	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HCAHIEPB_01282	3.26e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HCAHIEPB_01283	3.39e-148	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HCAHIEPB_01284	9.48e-111	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01285	6.35e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_01286	5.42e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCAHIEPB_01287	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_01289	2.54e-159	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HCAHIEPB_01292	3.64e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCAHIEPB_01293	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HCAHIEPB_01294	2.03e-262	-	-	-	V	-	-	-	VanZ like family
HCAHIEPB_01295	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01297	7.16e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCAHIEPB_01298	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HCAHIEPB_01299	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCAHIEPB_01300	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCAHIEPB_01301	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HCAHIEPB_01302	3.75e-255	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCAHIEPB_01303	5.94e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCAHIEPB_01304	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCAHIEPB_01305	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HCAHIEPB_01306	2.15e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCAHIEPB_01307	2.16e-238	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HCAHIEPB_01308	8.02e-119	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HCAHIEPB_01309	4.33e-160	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HCAHIEPB_01310	5.17e-223	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HCAHIEPB_01311	9.54e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCAHIEPB_01312	5.17e-227	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCAHIEPB_01313	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HCAHIEPB_01314	0.0	-	-	-	-	-	-	-	-
HCAHIEPB_01315	7.29e-219	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HCAHIEPB_01316	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HCAHIEPB_01317	3.57e-144	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HCAHIEPB_01318	1.33e-226	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCAHIEPB_01319	1.86e-214	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCAHIEPB_01320	4.63e-284	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HCAHIEPB_01322	1.08e-182	-	-	-	O	-	-	-	Thioredoxin
HCAHIEPB_01323	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HCAHIEPB_01324	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HCAHIEPB_01325	4.03e-43	-	-	-	T	-	-	-	LytTr DNA-binding domain
HCAHIEPB_01326	3.63e-35	-	-	-	T	-	-	-	LytTr DNA-binding domain
HCAHIEPB_01327	6.15e-153	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCAHIEPB_01328	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HCAHIEPB_01329	3.06e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCAHIEPB_01330	4.65e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HCAHIEPB_01331	1.72e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HCAHIEPB_01332	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCAHIEPB_01334	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCAHIEPB_01335	1.91e-280	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCAHIEPB_01336	1.66e-95	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCAHIEPB_01337	2.09e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCAHIEPB_01338	3.12e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HCAHIEPB_01339	2.91e-175	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
HCAHIEPB_01340	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCAHIEPB_01341	4.11e-68	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HCAHIEPB_01342	2.72e-182	-	-	-	L	-	-	-	Winged helix-turn helix
HCAHIEPB_01343	3.33e-232	-	-	-	-	-	-	-	-
HCAHIEPB_01344	6.14e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HCAHIEPB_01345	4.51e-222	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01346	6.91e-187	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HCAHIEPB_01347	7.94e-167	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01348	7.31e-22	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HCAHIEPB_01349	7.78e-200	-	-	-	-	-	-	-	-
HCAHIEPB_01350	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HCAHIEPB_01351	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HCAHIEPB_01352	6.27e-215	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HCAHIEPB_01353	2.26e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCAHIEPB_01354	2.78e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HCAHIEPB_01355	2.05e-314	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCAHIEPB_01356	1.58e-112	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCAHIEPB_01357	1.55e-20	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01358	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HCAHIEPB_01359	2.83e-133	-	-	-	-	-	-	-	-
HCAHIEPB_01360	8.25e-142	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HCAHIEPB_01361	7.72e-197	-	-	-	-	-	-	-	-
HCAHIEPB_01362	1.46e-187	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HCAHIEPB_01363	5.53e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCAHIEPB_01364	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HCAHIEPB_01365	2.07e-101	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCAHIEPB_01366	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HCAHIEPB_01367	9.36e-296	-	-	-	GK	-	-	-	ROK family
HCAHIEPB_01368	1.62e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01369	3.84e-208	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01370	3.04e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01371	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCAHIEPB_01372	1.91e-294	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HCAHIEPB_01373	7.18e-183	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HCAHIEPB_01374	1.81e-291	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01375	1.05e-28	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01376	6.96e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCAHIEPB_01377	2.51e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCAHIEPB_01378	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCAHIEPB_01379	5.79e-316	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HCAHIEPB_01380	1.38e-225	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HCAHIEPB_01381	4.11e-273	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCAHIEPB_01382	6.95e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCAHIEPB_01383	5.13e-137	-	-	-	-	-	-	-	-
HCAHIEPB_01384	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HCAHIEPB_01385	4.35e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCAHIEPB_01386	1.99e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCAHIEPB_01387	5.41e-204	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCAHIEPB_01388	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01389	3.75e-141	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HCAHIEPB_01390	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HCAHIEPB_01391	4.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HCAHIEPB_01392	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HCAHIEPB_01393	1.18e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HCAHIEPB_01394	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCAHIEPB_01395	3.87e-262	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCAHIEPB_01396	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCAHIEPB_01397	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCAHIEPB_01398	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCAHIEPB_01399	8.79e-09	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HCAHIEPB_01400	8.94e-179	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01401	7.84e-284	-	-	-	E	-	-	-	Aminotransferase class I and II
HCAHIEPB_01402	5.32e-244	-	-	-	P	-	-	-	NMT1/THI5 like
HCAHIEPB_01403	2.46e-173	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01404	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCAHIEPB_01405	6.84e-166	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HCAHIEPB_01406	0.0	-	-	-	I	-	-	-	acetylesterase activity
HCAHIEPB_01407	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCAHIEPB_01408	1.45e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCAHIEPB_01409	1.45e-296	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HCAHIEPB_01411	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HCAHIEPB_01412	2.12e-210	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HCAHIEPB_01413	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HCAHIEPB_01414	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCAHIEPB_01415	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HCAHIEPB_01416	3.25e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HCAHIEPB_01417	1.8e-215	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HCAHIEPB_01418	3.96e-165	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HCAHIEPB_01419	7.63e-218	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HCAHIEPB_01420	1.57e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HCAHIEPB_01421	8.15e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
HCAHIEPB_01422	2.76e-71	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_01423	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
HCAHIEPB_01424	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCAHIEPB_01425	3.8e-56	-	-	-	O	-	-	-	Glutaredoxin
HCAHIEPB_01426	1.57e-298	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCAHIEPB_01427	1.31e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HCAHIEPB_01428	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HCAHIEPB_01429	1.98e-06	-	-	-	-	-	-	-	-
HCAHIEPB_01430	2.93e-174	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HCAHIEPB_01431	9.2e-136	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCAHIEPB_01432	2.65e-217	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCAHIEPB_01433	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HCAHIEPB_01434	1.78e-307	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HCAHIEPB_01435	7.18e-121	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCAHIEPB_01436	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCAHIEPB_01437	5e-162	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01438	2.46e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HCAHIEPB_01439	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HCAHIEPB_01440	1.23e-72	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HCAHIEPB_01441	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
HCAHIEPB_01442	0.0	-	-	-	M	-	-	-	probably involved in cell wall
HCAHIEPB_01444	7.03e-62	-	4.1.1.44	-	L	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HCAHIEPB_01445	6.15e-239	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCAHIEPB_01446	6.79e-53	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCAHIEPB_01447	3.5e-149	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCAHIEPB_01448	3.95e-07	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HCAHIEPB_01449	9.33e-161	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
HCAHIEPB_01450	1.55e-308	-	-	-	V	-	-	-	MatE
HCAHIEPB_01451	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HCAHIEPB_01452	2.82e-139	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HCAHIEPB_01453	4.12e-271	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_01454	1.34e-35	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_01455	1.48e-246	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HCAHIEPB_01456	6.38e-87	-	-	-	K	-	-	-	MerR family regulatory protein
HCAHIEPB_01457	6.07e-114	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCAHIEPB_01458	9.65e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCAHIEPB_01459	3.75e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCAHIEPB_01461	5.88e-236	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HCAHIEPB_01462	9e-187	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HCAHIEPB_01463	2.99e-164	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HCAHIEPB_01464	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCAHIEPB_01465	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCAHIEPB_01466	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCAHIEPB_01467	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCAHIEPB_01468	1.94e-247	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HCAHIEPB_01470	1.22e-251	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HCAHIEPB_01471	1.29e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HCAHIEPB_01472	5.18e-291	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HCAHIEPB_01473	6.1e-294	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCAHIEPB_01474	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HCAHIEPB_01475	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HCAHIEPB_01476	2.92e-314	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCAHIEPB_01477	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HCAHIEPB_01478	1.61e-145	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HCAHIEPB_01479	3.96e-185	-	-	-	-	-	-	-	-
HCAHIEPB_01483	2.2e-131	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HCAHIEPB_01484	1.95e-19	-	-	-	C	-	-	-	Aldo/keto reductase family
HCAHIEPB_01485	3.86e-42	-	-	-	-	-	-	-	-
HCAHIEPB_01486	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HCAHIEPB_01487	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCAHIEPB_01488	5.52e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HCAHIEPB_01489	1.48e-309	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HCAHIEPB_01490	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HCAHIEPB_01491	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HCAHIEPB_01492	2.95e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HCAHIEPB_01493	3.75e-126	-	-	-	S	-	-	-	cobalamin synthesis protein
HCAHIEPB_01494	8.31e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HCAHIEPB_01495	5.79e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HCAHIEPB_01496	1.24e-58	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCAHIEPB_01497	1.72e-45	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCAHIEPB_01498	4.34e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HCAHIEPB_01499	6.34e-27	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
HCAHIEPB_01500	1.78e-34	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HCAHIEPB_01501	1.09e-253	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HCAHIEPB_01502	1.14e-179	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HCAHIEPB_01504	5.02e-47	-	-	-	-	-	-	-	-
HCAHIEPB_01505	1.89e-57	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HCAHIEPB_01506	9.71e-89	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCAHIEPB_01507	4.47e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_01508	1.65e-97	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_01509	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HCAHIEPB_01510	5.74e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCAHIEPB_01511	1.46e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCAHIEPB_01512	6.88e-232	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCAHIEPB_01513	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCAHIEPB_01514	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCAHIEPB_01515	1.71e-260	-	-	-	M	-	-	-	Conserved repeat domain
HCAHIEPB_01516	9.32e-184	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01517	6.28e-111	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
HCAHIEPB_01518	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HCAHIEPB_01519	3.62e-21	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01520	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCAHIEPB_01521	9.75e-295	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_01522	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01525	1.84e-204	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCAHIEPB_01526	1.34e-50	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HCAHIEPB_01527	9.8e-41	-	-	-	-	-	-	-	-
HCAHIEPB_01528	1.36e-267	-	-	-	P	-	-	-	Citrate transporter
HCAHIEPB_01529	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HCAHIEPB_01530	1.2e-148	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCAHIEPB_01531	1.9e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCAHIEPB_01532	9.51e-47	-	-	-	-	-	-	-	-
HCAHIEPB_01533	5.04e-90	-	-	-	S	-	-	-	PIN domain
HCAHIEPB_01534	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCAHIEPB_01535	2.91e-310	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HCAHIEPB_01536	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCAHIEPB_01537	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HCAHIEPB_01538	2.83e-88	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HCAHIEPB_01539	1.43e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HCAHIEPB_01540	3.71e-60	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HCAHIEPB_01541	9.76e-225	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
HCAHIEPB_01542	7.25e-243	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
HCAHIEPB_01543	1.59e-295	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
HCAHIEPB_01544	2.99e-83	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
HCAHIEPB_01545	1.7e-293	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCAHIEPB_01546	3.84e-215	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HCAHIEPB_01547	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
HCAHIEPB_01548	2.09e-44	-	-	-	-	-	-	-	-
HCAHIEPB_01549	5.31e-167	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01550	1.02e-170	-	-	-	U	ko:K02025,ko:K17242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01551	9.7e-201	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01552	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HCAHIEPB_01553	1.32e-303	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
HCAHIEPB_01554	3.17e-224	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCAHIEPB_01555	2.01e-144	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HCAHIEPB_01556	4.15e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCAHIEPB_01557	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCAHIEPB_01558	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HCAHIEPB_01559	7.5e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCAHIEPB_01560	1.42e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HCAHIEPB_01561	3.37e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01562	2.27e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HCAHIEPB_01563	8.92e-195	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01564	6.69e-216	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01565	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HCAHIEPB_01566	2.22e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCAHIEPB_01567	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01568	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01569	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01570	7.75e-153	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HCAHIEPB_01571	1.62e-78	-	-	-	V	-	-	-	HNH endonuclease
HCAHIEPB_01573	5.23e-97	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HCAHIEPB_01576	5.39e-69	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HCAHIEPB_01581	1.62e-35	-	-	-	-	-	-	-	-
HCAHIEPB_01589	1.87e-17	-	-	-	-	-	-	-	-
HCAHIEPB_01590	3.51e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3644)
HCAHIEPB_01591	4.84e-77	-	-	-	-	-	-	-	-
HCAHIEPB_01592	1.18e-91	-	-	-	-	-	-	-	-
HCAHIEPB_01593	3.08e-200	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_01595	2.85e-134	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
HCAHIEPB_01596	1.38e-256	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
HCAHIEPB_01597	5.2e-138	-	-	-	-	-	-	-	-
HCAHIEPB_01598	3.26e-274	-	-	-	-	-	-	-	-
HCAHIEPB_01599	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCAHIEPB_01600	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCAHIEPB_01601	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HCAHIEPB_01603	1.37e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCAHIEPB_01604	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HCAHIEPB_01605	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HCAHIEPB_01606	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HCAHIEPB_01607	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCAHIEPB_01608	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCAHIEPB_01609	1.45e-173	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HCAHIEPB_01612	1.91e-199	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCAHIEPB_01613	3.65e-225	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HCAHIEPB_01614	6.93e-281	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCAHIEPB_01615	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01616	2.81e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
HCAHIEPB_01617	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HCAHIEPB_01618	1.5e-52	-	-	-	-	-	-	-	-
HCAHIEPB_01619	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HCAHIEPB_01620	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCAHIEPB_01621	5.51e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HCAHIEPB_01622	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HCAHIEPB_01623	4.04e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCAHIEPB_01624	1.06e-313	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HCAHIEPB_01625	1.3e-78	-	-	-	-	-	-	-	-
HCAHIEPB_01626	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCAHIEPB_01627	1.56e-156	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCAHIEPB_01628	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCAHIEPB_01631	3.19e-307	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HCAHIEPB_01632	6.11e-311	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HCAHIEPB_01633	2.76e-216	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HCAHIEPB_01634	2.38e-148	safC	-	-	S	-	-	-	O-methyltransferase
HCAHIEPB_01635	3.43e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HCAHIEPB_01636	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HCAHIEPB_01637	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HCAHIEPB_01638	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HCAHIEPB_01639	8.76e-99	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HCAHIEPB_01640	4.32e-29	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_01641	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HCAHIEPB_01642	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HCAHIEPB_01643	4.4e-217	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_01644	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCAHIEPB_01645	3.52e-181	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_01646	0.0	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_01647	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HCAHIEPB_01648	1.1e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCAHIEPB_01649	3.42e-199	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HCAHIEPB_01650	6.4e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HCAHIEPB_01651	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01652	9.65e-143	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01653	2.16e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCAHIEPB_01654	2.7e-17	-	-	-	-	-	-	-	-
HCAHIEPB_01655	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HCAHIEPB_01656	5.08e-17	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HCAHIEPB_01657	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCAHIEPB_01658	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HCAHIEPB_01659	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCAHIEPB_01660	2.11e-223	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCAHIEPB_01661	5.28e-282	-	-	-	GK	-	-	-	ROK family
HCAHIEPB_01662	4.91e-204	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HCAHIEPB_01663	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HCAHIEPB_01664	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HCAHIEPB_01665	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HCAHIEPB_01666	2.15e-155	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HCAHIEPB_01667	9.17e-71	-	-	-	L	-	-	-	Helix-turn-helix domain
HCAHIEPB_01668	3.5e-54	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01669	1.02e-76	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HCAHIEPB_01670	2.5e-187	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCAHIEPB_01671	2.38e-83	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCAHIEPB_01673	3.66e-309	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HCAHIEPB_01674	1.54e-137	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HCAHIEPB_01675	1.72e-207	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HCAHIEPB_01676	2.42e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HCAHIEPB_01677	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HCAHIEPB_01678	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HCAHIEPB_01679	1.37e-212	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HCAHIEPB_01680	6.7e-148	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HCAHIEPB_01681	3.4e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_01682	1.38e-309	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_01683	4.49e-149	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HCAHIEPB_01684	7.53e-239	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01685	9.97e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCAHIEPB_01686	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCAHIEPB_01687	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HCAHIEPB_01688	6.13e-52	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCAHIEPB_01689	5.85e-260	-	-	-	-	-	-	-	-
HCAHIEPB_01690	6.64e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HCAHIEPB_01691	2.15e-138	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HCAHIEPB_01692	6.81e-222	-	-	-	M	-	-	-	pfam nlp p60
HCAHIEPB_01693	5.96e-202	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HCAHIEPB_01694	1.11e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HCAHIEPB_01695	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HCAHIEPB_01696	1.28e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HCAHIEPB_01697	1.48e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCAHIEPB_01698	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCAHIEPB_01699	3.12e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HCAHIEPB_01700	8.99e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_01701	2.6e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCAHIEPB_01702	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCAHIEPB_01703	6.43e-195	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HCAHIEPB_01704	1.01e-115	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
HCAHIEPB_01705	9.02e-69	-	-	-	S	-	-	-	SdpI/YhfL protein family
HCAHIEPB_01706	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HCAHIEPB_01707	8.67e-85	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCAHIEPB_01708	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HCAHIEPB_01709	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HCAHIEPB_01710	1.28e-76	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HCAHIEPB_01711	6.59e-48	-	-	-	-	-	-	-	-
HCAHIEPB_01712	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCAHIEPB_01713	6.08e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCAHIEPB_01714	5.37e-255	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCAHIEPB_01715	1.01e-90	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HCAHIEPB_01716	2.9e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCAHIEPB_01717	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCAHIEPB_01718	2.98e-104	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HCAHIEPB_01719	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCAHIEPB_01720	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCAHIEPB_01721	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HCAHIEPB_01722	2.06e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HCAHIEPB_01723	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HCAHIEPB_01724	1.46e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCAHIEPB_01725	8.33e-133	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HCAHIEPB_01726	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCAHIEPB_01727	2.27e-309	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCAHIEPB_01728	7.89e-212	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HCAHIEPB_01730	4.41e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCAHIEPB_01731	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HCAHIEPB_01732	3.13e-274	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HCAHIEPB_01733	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCAHIEPB_01734	0.0	corC	-	-	S	-	-	-	CBS domain
HCAHIEPB_01735	2.23e-235	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCAHIEPB_01736	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HCAHIEPB_01737	2.83e-262	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HCAHIEPB_01738	3.55e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HCAHIEPB_01739	2.11e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HCAHIEPB_01740	8.78e-300	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HCAHIEPB_01741	2.59e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCAHIEPB_01742	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HCAHIEPB_01743	3.22e-191	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01744	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
HCAHIEPB_01745	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HCAHIEPB_01746	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCAHIEPB_01747	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HCAHIEPB_01749	1.59e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_01750	3.03e-32	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
HCAHIEPB_01751	6.47e-44	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_01752	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HCAHIEPB_01753	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HCAHIEPB_01755	5.77e-58	-	-	-	-	-	-	-	-
HCAHIEPB_01756	9.86e-80	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HCAHIEPB_01757	4.63e-71	-	-	-	T	-	-	-	Histidine kinase
HCAHIEPB_01759	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HCAHIEPB_01760	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HCAHIEPB_01761	1.02e-107	-	-	-	-	-	-	-	-
HCAHIEPB_01762	2.77e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HCAHIEPB_01763	2.53e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01764	7.27e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCAHIEPB_01766	1.86e-45	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score 8.96
HCAHIEPB_01768	6.86e-14	-	-	-	L	-	-	-	Transposase
HCAHIEPB_01769	9.18e-41	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HCAHIEPB_01770	2.77e-112	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HCAHIEPB_01771	8.39e-285	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
HCAHIEPB_01772	1.31e-181	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCAHIEPB_01773	8.48e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCAHIEPB_01774	3.96e-178	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HCAHIEPB_01775	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HCAHIEPB_01776	5.84e-92	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HCAHIEPB_01777	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCAHIEPB_01778	3.33e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCAHIEPB_01780	1.78e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HCAHIEPB_01781	0.0	ptsP	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCAHIEPB_01782	9.36e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCAHIEPB_01783	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HCAHIEPB_01784	9.49e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HCAHIEPB_01785	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HCAHIEPB_01786	4.16e-143	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCAHIEPB_01787	4.23e-217	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HCAHIEPB_01788	4.73e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCAHIEPB_01789	2.66e-229	-	-	-	-	-	-	-	-
HCAHIEPB_01790	3.79e-171	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01791	7.57e-68	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCAHIEPB_01792	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCAHIEPB_01793	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCAHIEPB_01794	2.37e-248	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCAHIEPB_01795	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HCAHIEPB_01796	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HCAHIEPB_01797	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCAHIEPB_01799	6.12e-47	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HCAHIEPB_01800	4.05e-189	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_01801	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
HCAHIEPB_01802	2.65e-192	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01803	2.39e-157	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01804	7.65e-146	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01805	1.78e-157	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HCAHIEPB_01806	7.25e-64	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HCAHIEPB_01807	7.71e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HCAHIEPB_01808	0.0	-	-	-	S	-	-	-	domain protein
HCAHIEPB_01809	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCAHIEPB_01810	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCAHIEPB_01811	4.17e-163	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCAHIEPB_01812	5.92e-170	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HCAHIEPB_01813	1.07e-123	-	-	-	-	-	-	-	-
HCAHIEPB_01814	1.93e-126	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HCAHIEPB_01815	1.95e-119	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HCAHIEPB_01816	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HCAHIEPB_01817	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HCAHIEPB_01818	1.89e-121	-	-	-	L	-	-	-	Phage integrase family
HCAHIEPB_01822	6.28e-33	-	-	-	-	-	-	-	-
HCAHIEPB_01823	6.12e-97	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HCAHIEPB_01824	1.63e-12	-	-	-	-	-	-	-	-
HCAHIEPB_01827	2.53e-134	-	-	-	-	-	-	-	-
HCAHIEPB_01828	2.46e-305	-	-	-	NT	-	-	-	phage tail tape measure protein
HCAHIEPB_01829	1.17e-25	-	-	-	-	-	-	-	-
HCAHIEPB_01830	5.21e-70	-	-	-	-	-	-	-	-
HCAHIEPB_01831	5.66e-76	-	-	-	-	-	-	-	-
HCAHIEPB_01832	7.89e-26	-	-	-	-	-	-	-	-
HCAHIEPB_01833	1.52e-18	-	-	-	-	-	-	-	-
HCAHIEPB_01835	6.09e-162	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HCAHIEPB_01836	4.16e-114	-	-	-	S	-	-	-	Phage portal protein
HCAHIEPB_01837	1.48e-151	-	-	-	S	-	-	-	Terminase
HCAHIEPB_01838	2.47e-21	-	-	-	-	-	-	-	-
HCAHIEPB_01839	7.81e-07	-	-	-	L	-	-	-	HNH nucleases
HCAHIEPB_01841	7.49e-35	-	-	-	-	-	-	-	-
HCAHIEPB_01847	8.77e-16	-	-	-	K	-	-	-	BetR domain
HCAHIEPB_01849	2.47e-263	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCAHIEPB_01850	7.71e-187	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HCAHIEPB_01851	9.96e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCAHIEPB_01852	2.76e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCAHIEPB_01853	1.27e-185	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCAHIEPB_01854	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCAHIEPB_01855	3.59e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCAHIEPB_01856	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCAHIEPB_01857	3.62e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCAHIEPB_01858	1.23e-165	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HCAHIEPB_01859	5.97e-215	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HCAHIEPB_01860	2.14e-242	-	-	-	-	-	-	-	-
HCAHIEPB_01861	5.43e-231	-	-	-	-	-	-	-	-
HCAHIEPB_01862	5.13e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HCAHIEPB_01863	3.19e-151	-	-	-	S	-	-	-	CYTH
HCAHIEPB_01866	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HCAHIEPB_01867	2.95e-240	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HCAHIEPB_01868	3.39e-229	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HCAHIEPB_01869	1e-291	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCAHIEPB_01870	2.49e-277	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01871	6.88e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01872	2.04e-170	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01873	7.87e-304	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCAHIEPB_01874	3.72e-239	-	-	-	S	-	-	-	CAAX protease self-immunity
HCAHIEPB_01875	3.93e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
HCAHIEPB_01876	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HCAHIEPB_01878	2.84e-172	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HCAHIEPB_01879	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HCAHIEPB_01880	2.02e-247	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCAHIEPB_01881	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HCAHIEPB_01882	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01883	1.52e-210	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01884	1.14e-227	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01885	5.26e-300	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HCAHIEPB_01886	2.15e-09	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01888	8.04e-49	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01889	7.86e-40	-	-	-	L	-	-	-	Transposase
HCAHIEPB_01890	2.38e-72	-	-	-	L	-	-	-	PFAM Integrase catalytic
HCAHIEPB_01891	0.0	-	-	-	C	-	-	-	Domain of unknown function (DUF4365)
HCAHIEPB_01892	1.69e-58	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
HCAHIEPB_01894	2.56e-115	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCAHIEPB_01896	3.2e-60	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HCAHIEPB_01897	1.51e-128	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HCAHIEPB_01899	3.97e-12	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_01900	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HCAHIEPB_01901	2.88e-91	-	-	-	-	-	-	-	-
HCAHIEPB_01902	6.64e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HCAHIEPB_01903	2.24e-273	-	-	-	-	-	-	-	-
HCAHIEPB_01904	7.3e-221	-	-	-	S	ko:K21688	-	ko00000	G5
HCAHIEPB_01905	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HCAHIEPB_01906	7.47e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HCAHIEPB_01907	2.34e-203	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HCAHIEPB_01908	1.7e-281	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HCAHIEPB_01909	1.26e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HCAHIEPB_01910	4.05e-284	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HCAHIEPB_01911	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HCAHIEPB_01912	7.3e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCAHIEPB_01913	9.39e-277	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HCAHIEPB_01914	2.7e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HCAHIEPB_01915	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HCAHIEPB_01916	9.99e-305	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HCAHIEPB_01917	3.75e-290	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HCAHIEPB_01918	3.61e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HCAHIEPB_01919	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HCAHIEPB_01920	2.92e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HCAHIEPB_01921	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HCAHIEPB_01922	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCAHIEPB_01923	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCAHIEPB_01924	5.09e-238	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HCAHIEPB_01925	1.56e-165	-	-	-	-	-	-	-	-
HCAHIEPB_01926	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCAHIEPB_01927	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCAHIEPB_01928	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HCAHIEPB_01929	5.59e-309	-	-	-	S	-	-	-	Protein of unknown function DUF58
HCAHIEPB_01930	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HCAHIEPB_01931	7.2e-283	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HCAHIEPB_01932	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HCAHIEPB_01933	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HCAHIEPB_01934	9.52e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCAHIEPB_01935	2.66e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCAHIEPB_01936	2.06e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCAHIEPB_01937	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCAHIEPB_01938	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HCAHIEPB_01939	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCAHIEPB_01940	5.28e-159	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCAHIEPB_01941	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01942	2.52e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCAHIEPB_01943	7.91e-270	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HCAHIEPB_01944	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HCAHIEPB_01945	2.5e-210	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HCAHIEPB_01946	3.26e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCAHIEPB_01947	8.22e-203	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HCAHIEPB_01948	1.53e-215	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HCAHIEPB_01949	3.78e-223	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01950	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01951	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCAHIEPB_01952	1.46e-179	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HCAHIEPB_01953	9.16e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
HCAHIEPB_01954	6.32e-55	-	-	-	-	-	-	-	-
HCAHIEPB_01955	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HCAHIEPB_01956	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HCAHIEPB_01957	4.19e-46	nfrA	-	-	C	-	-	-	Nitroreductase family
HCAHIEPB_01958	9.42e-119	nfrA	-	-	C	-	-	-	Nitroreductase family
HCAHIEPB_01959	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HCAHIEPB_01960	1.29e-132	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HCAHIEPB_01961	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCAHIEPB_01962	8.42e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HCAHIEPB_01963	3.16e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01964	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCAHIEPB_01965	8.13e-137	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HCAHIEPB_01966	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HCAHIEPB_01967	2.49e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCAHIEPB_01968	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_01969	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCAHIEPB_01970	8.65e-53	-	-	-	L	-	-	-	Transposase
HCAHIEPB_01971	1.55e-31	-	-	-	L	-	-	-	Transposase DDE domain
HCAHIEPB_01972	3.77e-09	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_01973	1.26e-116	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_01974	2.46e-270	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HCAHIEPB_01975	0.0	-	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCAHIEPB_01976	8.64e-190	-	-	-	U	ko:K02057,ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HCAHIEPB_01977	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HCAHIEPB_01978	2.4e-185	-	-	-	-	-	-	-	-
HCAHIEPB_01979	1.81e-252	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCAHIEPB_01980	4.43e-16	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HCAHIEPB_01981	4.11e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HCAHIEPB_01982	2.43e-34	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_01983	2.92e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
HCAHIEPB_01985	1.38e-10	-	-	-	JM	-	-	-	Carbohydrate binding module (family 6)
HCAHIEPB_01986	9.48e-120	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCAHIEPB_01987	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_01988	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HCAHIEPB_01989	3.69e-232	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCAHIEPB_01990	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HCAHIEPB_01992	1.29e-236	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCAHIEPB_01993	5.33e-156	-	-	-	-	-	-	-	-
HCAHIEPB_01994	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCAHIEPB_01995	7.04e-63	-	-	-	-	-	-	-	-
HCAHIEPB_01996	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HCAHIEPB_01997	8.66e-229	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCAHIEPB_01998	8.61e-227	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HCAHIEPB_01999	8.57e-227	-	-	-	E	ko:K02031,ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCAHIEPB_02000	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCAHIEPB_02001	8.8e-55	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HCAHIEPB_02002	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HCAHIEPB_02003	5.54e-29	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HCAHIEPB_02004	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCAHIEPB_02005	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCAHIEPB_02006	3.31e-238	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HCAHIEPB_02007	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HCAHIEPB_02008	8.58e-206	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HCAHIEPB_02009	7.76e-184	-	-	-	T	ko:K06950	-	ko00000	HD domain
HCAHIEPB_02010	1.32e-243	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCAHIEPB_02011	0.0	-	-	-	V	-	-	-	ABC transporter permease
HCAHIEPB_02012	6.86e-246	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HCAHIEPB_02013	2.67e-24	-	-	-	-	-	-	-	-
HCAHIEPB_02014	1.07e-286	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HCAHIEPB_02015	1.61e-220	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCAHIEPB_02016	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCAHIEPB_02017	1.63e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCAHIEPB_02018	6.02e-184	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HCAHIEPB_02019	1.74e-290	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_02020	2.94e-188	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HCAHIEPB_02021	2.01e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCAHIEPB_02022	1.64e-143	-	-	-	-	-	-	-	-
HCAHIEPB_02023	1.94e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCAHIEPB_02024	2.87e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HCAHIEPB_02025	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HCAHIEPB_02026	1.31e-245	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HCAHIEPB_02027	1.1e-90	-	-	-	V	-	-	-	Abi-like protein
HCAHIEPB_02028	1.74e-273	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HCAHIEPB_02029	1.44e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_02030	2.45e-119	-	-	-	-	-	-	-	-
HCAHIEPB_02031	3.21e-213	-	-	-	-	-	-	-	-
HCAHIEPB_02032	3.31e-194	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
HCAHIEPB_02034	2.63e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
HCAHIEPB_02035	6.21e-172	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HCAHIEPB_02036	1.13e-222	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
HCAHIEPB_02037	8.26e-294	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HCAHIEPB_02038	0.0	-	-	-	S	-	-	-	FRG domain
HCAHIEPB_02039	0.0	-	-	-	T	-	-	-	AAA domain
HCAHIEPB_02040	8.39e-38	-	-	-	-	-	-	-	-
HCAHIEPB_02041	0.0	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HCAHIEPB_02043	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HCAHIEPB_02044	5.41e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HCAHIEPB_02045	5e-292	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HCAHIEPB_02046	7.36e-291	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCAHIEPB_02047	1.15e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCAHIEPB_02048	1.62e-186	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCAHIEPB_02049	1.68e-102	-	-	-	S	-	-	-	FMN_bind
HCAHIEPB_02050	6.6e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HCAHIEPB_02051	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HCAHIEPB_02052	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HCAHIEPB_02053	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HCAHIEPB_02054	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCAHIEPB_02055	2.39e-191	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HCAHIEPB_02056	1.04e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HCAHIEPB_02057	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCAHIEPB_02058	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HCAHIEPB_02060	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HCAHIEPB_02061	2.29e-253	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HCAHIEPB_02062	1.23e-194	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCAHIEPB_02063	4.83e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCAHIEPB_02064	1.12e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HCAHIEPB_02065	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HCAHIEPB_02066	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HCAHIEPB_02067	4.25e-305	dinF	-	-	V	-	-	-	MatE
HCAHIEPB_02068	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HCAHIEPB_02069	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HCAHIEPB_02070	5.46e-182	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HCAHIEPB_02071	2.49e-53	-	-	-	S	-	-	-	granule-associated protein
HCAHIEPB_02072	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HCAHIEPB_02073	1.28e-213	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HCAHIEPB_02074	4.9e-42	-	-	-	L	-	-	-	Transposase
HCAHIEPB_02075	6.91e-56	-	-	-	L	-	-	-	Transposase