ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GKMKNIOF_00001 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_00002 2.8e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKMKNIOF_00003 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GKMKNIOF_00004 4.69e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKMKNIOF_00005 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKMKNIOF_00006 1.69e-06 - - - - - - - -
GKMKNIOF_00007 2.1e-31 - - - - - - - -
GKMKNIOF_00008 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_00009 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GKMKNIOF_00010 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GKMKNIOF_00011 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKMKNIOF_00012 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKMKNIOF_00013 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GKMKNIOF_00014 2.08e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKMKNIOF_00015 8.68e-171 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GKMKNIOF_00016 8.3e-59 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_00018 1.87e-308 - - - S - - - response to antibiotic
GKMKNIOF_00019 1.34e-162 - - - - - - - -
GKMKNIOF_00020 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKMKNIOF_00021 6.28e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GKMKNIOF_00022 1.42e-57 - - - - - - - -
GKMKNIOF_00023 4.65e-14 - - - - - - - -
GKMKNIOF_00024 7.81e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GKMKNIOF_00025 8.28e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKMKNIOF_00026 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
GKMKNIOF_00027 8.75e-197 - - - - - - - -
GKMKNIOF_00028 3.32e-13 - - - - - - - -
GKMKNIOF_00029 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKMKNIOF_00030 5.6e-135 - - - K ko:K06977 - ko00000 acetyltransferase
GKMKNIOF_00033 4.92e-20 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GKMKNIOF_00034 1.23e-58 - - - S - - - polysaccharide biosynthetic process
GKMKNIOF_00035 6.06e-41 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKMKNIOF_00036 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GKMKNIOF_00037 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GKMKNIOF_00038 4.05e-209 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
GKMKNIOF_00039 2.84e-240 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GKMKNIOF_00040 2.51e-184 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GKMKNIOF_00041 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GKMKNIOF_00042 1.48e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKMKNIOF_00043 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GKMKNIOF_00044 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
GKMKNIOF_00045 4.16e-280 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKMKNIOF_00046 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GKMKNIOF_00047 3.94e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GKMKNIOF_00048 1.06e-58 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
GKMKNIOF_00050 1.86e-56 - - - E - - - Pfam:DUF955
GKMKNIOF_00051 1.19e-31 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GKMKNIOF_00052 7.33e-19 - - - - - - - -
GKMKNIOF_00054 2.62e-155 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GKMKNIOF_00056 7.63e-28 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKMKNIOF_00058 2.78e-45 - - - - - - - -
GKMKNIOF_00059 1.54e-87 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
GKMKNIOF_00061 5.85e-67 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00062 1.78e-21 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00064 7.62e-32 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKMKNIOF_00065 8.24e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GKMKNIOF_00066 4.68e-25 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKMKNIOF_00067 7.98e-35 - - - GKT - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKMKNIOF_00068 1.71e-156 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GKMKNIOF_00071 4.19e-92 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GKMKNIOF_00072 8.41e-89 - - - L - - - Psort location Cytoplasmic, score
GKMKNIOF_00073 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GKMKNIOF_00074 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_00075 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
GKMKNIOF_00076 2.52e-303 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
GKMKNIOF_00078 0.0 - - - S - - - SLAP domain
GKMKNIOF_00079 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
GKMKNIOF_00080 3.68e-276 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GKMKNIOF_00081 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GKMKNIOF_00082 1e-156 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GKMKNIOF_00083 6.33e-63 - - - L - - - Psort location Cytoplasmic, score 8.96
GKMKNIOF_00084 1.8e-139 - - - L - - - PFAM Integrase catalytic
GKMKNIOF_00085 2.28e-76 eriC - - P ko:K03281 - ko00000 chloride
GKMKNIOF_00086 1.59e-66 eriC - - P ko:K03281 - ko00000 chloride
GKMKNIOF_00087 2.94e-74 eriC - - P ko:K03281 - ko00000 chloride
GKMKNIOF_00088 1.45e-34 - - - K - - - FCD
GKMKNIOF_00089 3.87e-20 - - - K - - - FCD
GKMKNIOF_00090 4.37e-132 - - - GM - - - NmrA-like family
GKMKNIOF_00091 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKMKNIOF_00092 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKMKNIOF_00093 6.2e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKMKNIOF_00094 1.01e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKMKNIOF_00095 9.05e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GKMKNIOF_00096 2.04e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKMKNIOF_00097 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKMKNIOF_00098 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKMKNIOF_00099 6.69e-115 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKMKNIOF_00100 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GKMKNIOF_00101 4.97e-311 ynbB - - P - - - aluminum resistance
GKMKNIOF_00102 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GKMKNIOF_00103 0.0 - - - E - - - Amino acid permease
GKMKNIOF_00104 7.88e-121 - - - C - - - Pyridoxamine 5'-phosphate oxidase
GKMKNIOF_00105 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GKMKNIOF_00106 3.03e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKMKNIOF_00107 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GKMKNIOF_00108 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKMKNIOF_00109 9.93e-72 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKMKNIOF_00110 5.49e-197 - - - L - - - Phage integrase, N-terminal SAM-like domain
GKMKNIOF_00111 5.61e-124 - - - M - - - LysM domain protein
GKMKNIOF_00112 6.38e-59 - - - S - - - aldo-keto reductase (NADP) activity
GKMKNIOF_00113 1.19e-97 - - - C - - - Aldo keto reductase
GKMKNIOF_00114 3.83e-231 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GKMKNIOF_00115 3.53e-35 - - - C ko:K21832 - ko00000 nitric oxide dioxygenase activity
GKMKNIOF_00116 1.61e-48 - - - S - - - Cytochrome B5
GKMKNIOF_00117 1.87e-213 arbZ - - I - - - Phosphate acyltransferases
GKMKNIOF_00118 5.48e-235 - - - M - - - Glycosyl transferase family 8
GKMKNIOF_00119 1.91e-236 - - - M - - - Glycosyl transferase family 8
GKMKNIOF_00120 7.23e-201 arbx - - M - - - Glycosyl transferase family 8
GKMKNIOF_00121 4.19e-192 - - - I - - - Acyl-transferase
GKMKNIOF_00123 1.09e-46 - - - - - - - -
GKMKNIOF_00125 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GKMKNIOF_00126 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKMKNIOF_00127 0.0 yycH - - S - - - YycH protein
GKMKNIOF_00128 7.44e-192 yycI - - S - - - YycH protein
GKMKNIOF_00129 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GKMKNIOF_00130 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GKMKNIOF_00131 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKMKNIOF_00132 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKMKNIOF_00133 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKMKNIOF_00134 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKMKNIOF_00135 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GKMKNIOF_00136 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKMKNIOF_00137 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKMKNIOF_00138 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKMKNIOF_00139 3.94e-183 - - - P - - - Voltage gated chloride channel
GKMKNIOF_00140 2.83e-237 - - - C - - - FMN-dependent dehydrogenase
GKMKNIOF_00141 1.05e-69 - - - - - - - -
GKMKNIOF_00142 1.17e-56 - - - - - - - -
GKMKNIOF_00143 1.33e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKMKNIOF_00144 0.0 - - - E - - - amino acid
GKMKNIOF_00145 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKMKNIOF_00146 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
GKMKNIOF_00147 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GKMKNIOF_00148 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKMKNIOF_00149 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKMKNIOF_00150 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKMKNIOF_00151 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKMKNIOF_00152 5.53e-173 - - - S - - - TerB-C domain
GKMKNIOF_00153 2.14e-312 - - - P - - - P-loop Domain of unknown function (DUF2791)
GKMKNIOF_00154 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
GKMKNIOF_00155 7.82e-80 - - - - - - - -
GKMKNIOF_00156 1.49e-290 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GKMKNIOF_00157 5.4e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GKMKNIOF_00159 4.51e-77 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GKMKNIOF_00160 1.08e-145 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GKMKNIOF_00161 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
GKMKNIOF_00163 1.04e-41 - - - - - - - -
GKMKNIOF_00164 2.77e-220 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
GKMKNIOF_00165 1.25e-17 - - - - - - - -
GKMKNIOF_00166 1.83e-22 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_00167 6.31e-99 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_00168 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_00169 1.33e-130 - - - M - - - LysM domain protein
GKMKNIOF_00170 5.17e-169 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GKMKNIOF_00171 4.78e-308 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GKMKNIOF_00172 4.71e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKMKNIOF_00173 0.0 potE - - E - - - Amino Acid
GKMKNIOF_00174 9.84e-63 - - - S - - - Fic/DOC family
GKMKNIOF_00176 0.0 - - - - - - - -
GKMKNIOF_00177 2.05e-110 - - - - - - - -
GKMKNIOF_00178 1.92e-113 yhaH - - S - - - Protein of unknown function (DUF805)
GKMKNIOF_00179 2.65e-89 - - - O - - - OsmC-like protein
GKMKNIOF_00180 5.3e-264 - - - EGP - - - Major Facilitator Superfamily
GKMKNIOF_00181 3e-290 sptS - - T - - - Histidine kinase
GKMKNIOF_00182 2.14e-85 dltr - - K - - - response regulator
GKMKNIOF_00183 4.52e-35 dltr - - K - - - response regulator
GKMKNIOF_00184 3.99e-127 - - - T - - - Region found in RelA / SpoT proteins
GKMKNIOF_00185 5.03e-76 - - - K - - - Helix-turn-helix domain
GKMKNIOF_00186 1.17e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKMKNIOF_00187 1.05e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GKMKNIOF_00188 1.11e-234 - - - K - - - Transcriptional regulator
GKMKNIOF_00189 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKMKNIOF_00190 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKMKNIOF_00191 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKMKNIOF_00192 0.0 snf - - KL - - - domain protein
GKMKNIOF_00193 1.32e-171 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKMKNIOF_00194 1.45e-36 - - - S - - - Peptidase propeptide and YPEB domain
GKMKNIOF_00195 1.73e-79 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GKMKNIOF_00196 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_00197 1.13e-201 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GKMKNIOF_00198 2.91e-83 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GKMKNIOF_00199 8.64e-85 yybA - - K - - - Transcriptional regulator
GKMKNIOF_00200 8e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKMKNIOF_00201 5.59e-109 - - - S - - - Peptidase propeptide and YPEB domain
GKMKNIOF_00202 2.88e-98 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GKMKNIOF_00203 2.37e-242 - - - T - - - GHKL domain
GKMKNIOF_00204 1.75e-168 - - - T - - - Transcriptional regulatory protein, C terminal
GKMKNIOF_00205 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GKMKNIOF_00206 0.0 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_00207 1.34e-22 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GKMKNIOF_00208 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKMKNIOF_00209 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GKMKNIOF_00210 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GKMKNIOF_00211 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GKMKNIOF_00212 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKMKNIOF_00213 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKMKNIOF_00214 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GKMKNIOF_00215 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GKMKNIOF_00216 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GKMKNIOF_00217 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKMKNIOF_00218 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKMKNIOF_00219 5.59e-98 - - - - - - - -
GKMKNIOF_00220 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKMKNIOF_00221 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GKMKNIOF_00222 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GKMKNIOF_00223 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKMKNIOF_00224 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKMKNIOF_00225 7.81e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKMKNIOF_00226 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKMKNIOF_00227 1.98e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GKMKNIOF_00228 2.53e-139 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GKMKNIOF_00229 1.33e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GKMKNIOF_00230 2.43e-239 - - - S - - - Bacteriocin helveticin-J
GKMKNIOF_00231 1.64e-19 - - - - - - - -
GKMKNIOF_00232 4.26e-22 - - - L ko:K07467 - ko00000 Replication initiation factor
GKMKNIOF_00233 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKMKNIOF_00234 5.23e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GKMKNIOF_00235 1.48e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKMKNIOF_00236 1.07e-141 tnpR1 - - L - - - Resolvase, N terminal domain
GKMKNIOF_00237 6.91e-92 - - - L - - - IS1381, transposase OrfA
GKMKNIOF_00238 4.87e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKMKNIOF_00239 1.17e-38 - - - - - - - -
GKMKNIOF_00240 4.65e-184 - - - D - - - AAA domain
GKMKNIOF_00241 5.88e-212 repA - - S - - - Replication initiator protein A
GKMKNIOF_00242 1.14e-164 - - - S - - - Fic/DOC family
GKMKNIOF_00243 5.61e-38 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKMKNIOF_00245 2.23e-189 - - - S - - - Putative ABC-transporter type IV
GKMKNIOF_00247 4.11e-124 potE - - E - - - thought to be involved in transport amino acids across the membrane
GKMKNIOF_00249 2.67e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKMKNIOF_00250 6.66e-27 - - - S - - - CAAX protease self-immunity
GKMKNIOF_00252 1.25e-94 - - - K - - - Helix-turn-helix domain
GKMKNIOF_00253 4.82e-144 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_00256 2.41e-39 - - - - - - - -
GKMKNIOF_00257 7.74e-61 - - - - - - - -
GKMKNIOF_00258 1.84e-44 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKMKNIOF_00259 1.94e-150 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKMKNIOF_00260 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKMKNIOF_00261 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GKMKNIOF_00262 1.74e-111 - - - - - - - -
GKMKNIOF_00263 7.76e-98 - - - - - - - -
GKMKNIOF_00264 1.76e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
GKMKNIOF_00265 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKMKNIOF_00266 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GKMKNIOF_00267 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GKMKNIOF_00268 1.28e-168 - - - L - - - PFAM transposase IS116 IS110 IS902
GKMKNIOF_00269 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKMKNIOF_00270 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKMKNIOF_00271 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKMKNIOF_00272 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKMKNIOF_00273 5.35e-224 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKMKNIOF_00274 3.68e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GKMKNIOF_00275 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
GKMKNIOF_00303 4.28e-187 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GKMKNIOF_00304 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKMKNIOF_00305 3.09e-71 - - - - - - - -
GKMKNIOF_00306 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKMKNIOF_00307 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GKMKNIOF_00308 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKMKNIOF_00309 9.89e-74 - - - - - - - -
GKMKNIOF_00310 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKMKNIOF_00311 4.25e-119 yutD - - S - - - Protein of unknown function (DUF1027)
GKMKNIOF_00312 6.38e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKMKNIOF_00313 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
GKMKNIOF_00314 6.9e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GKMKNIOF_00315 1.76e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GKMKNIOF_00316 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
GKMKNIOF_00317 1.13e-126 - - - - - - - -
GKMKNIOF_00318 6.93e-140 - - - K - - - LysR substrate binding domain
GKMKNIOF_00319 4.04e-29 - - - - - - - -
GKMKNIOF_00320 1.07e-287 - - - S - - - Sterol carrier protein domain
GKMKNIOF_00321 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GKMKNIOF_00322 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GKMKNIOF_00323 5.39e-84 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKMKNIOF_00324 2.06e-298 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GKMKNIOF_00325 3.03e-177 lysR5 - - K - - - LysR substrate binding domain
GKMKNIOF_00326 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
GKMKNIOF_00327 4.97e-64 - - - S - - - Metal binding domain of Ada
GKMKNIOF_00328 1.6e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
GKMKNIOF_00329 1.56e-198 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GKMKNIOF_00330 1.63e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GKMKNIOF_00331 1.03e-47 - - - - - - - -
GKMKNIOF_00332 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GKMKNIOF_00333 7.8e-155 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_00334 3.86e-109 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_00335 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GKMKNIOF_00336 4.14e-113 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GKMKNIOF_00338 2e-149 - - - S - - - Peptidase family M23
GKMKNIOF_00339 1.22e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKMKNIOF_00341 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKMKNIOF_00342 5.47e-151 - - - - - - - -
GKMKNIOF_00343 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKMKNIOF_00344 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GKMKNIOF_00345 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GKMKNIOF_00346 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKMKNIOF_00347 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
GKMKNIOF_00348 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_00349 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_00350 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKMKNIOF_00351 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GKMKNIOF_00353 7.03e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKMKNIOF_00354 0.0 - - - S - - - Fibronectin type III domain
GKMKNIOF_00355 1.03e-65 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GKMKNIOF_00356 7.41e-136 - - - - - - - -
GKMKNIOF_00357 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
GKMKNIOF_00358 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GKMKNIOF_00359 4.44e-65 - - - S - - - Cupredoxin-like domain
GKMKNIOF_00360 2.52e-76 - - - S - - - Cupredoxin-like domain
GKMKNIOF_00361 2.23e-48 - - - - - - - -
GKMKNIOF_00365 2.27e-179 - - - - - - - -
GKMKNIOF_00366 0.0 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_00367 7.23e-50 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKMKNIOF_00368 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
GKMKNIOF_00369 1.51e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GKMKNIOF_00370 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKMKNIOF_00371 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKMKNIOF_00372 9.78e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GKMKNIOF_00373 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_00374 1.36e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKMKNIOF_00375 1.88e-125 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKMKNIOF_00376 1.95e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GKMKNIOF_00377 1.48e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKMKNIOF_00378 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
GKMKNIOF_00379 3.99e-56 - - - L - - - PFAM transposase IS116 IS110 IS902
GKMKNIOF_00380 3.76e-18 - - - K - - - Acetyltransferase (GNAT) domain
GKMKNIOF_00381 7.51e-16 - - - L - - - Transposase
GKMKNIOF_00382 1.01e-22 - - - L - - - Transposase
GKMKNIOF_00383 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GKMKNIOF_00384 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
GKMKNIOF_00385 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GKMKNIOF_00386 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
GKMKNIOF_00387 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
GKMKNIOF_00388 4.82e-42 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKMKNIOF_00389 6.58e-293 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GKMKNIOF_00390 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKMKNIOF_00391 6.33e-221 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
GKMKNIOF_00392 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GKMKNIOF_00393 2.65e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKMKNIOF_00394 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKMKNIOF_00395 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKMKNIOF_00396 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKMKNIOF_00397 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GKMKNIOF_00398 5.38e-39 - - - - - - - -
GKMKNIOF_00399 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKMKNIOF_00400 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKMKNIOF_00401 1.13e-41 - - - M - - - Lysin motif
GKMKNIOF_00402 1.96e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GKMKNIOF_00403 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GKMKNIOF_00404 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GKMKNIOF_00405 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKMKNIOF_00406 3.52e-293 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GKMKNIOF_00407 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKMKNIOF_00408 9.41e-285 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_00409 1.21e-243 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKMKNIOF_00411 1.73e-227 - - - S - - - Conserved hypothetical protein 698
GKMKNIOF_00412 1.63e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GKMKNIOF_00413 3.87e-15 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
GKMKNIOF_00414 1.35e-129 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
GKMKNIOF_00415 2.43e-95 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKMKNIOF_00416 4.36e-93 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKMKNIOF_00417 8.44e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GKMKNIOF_00418 0.0 eriC - - P ko:K03281 - ko00000 chloride
GKMKNIOF_00419 1.98e-41 - - - E - - - Zn peptidase
GKMKNIOF_00420 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_00421 2.35e-58 - - - - - - - -
GKMKNIOF_00422 1.06e-133 - - - S - - - Bacteriocin helveticin-J
GKMKNIOF_00423 1.14e-154 - - - S - - - SLAP domain
GKMKNIOF_00424 6.57e-175 - - - S - - - SLAP domain
GKMKNIOF_00425 6.49e-268 - - - - - - - -
GKMKNIOF_00426 6.46e-27 - - - - - - - -
GKMKNIOF_00427 2.71e-222 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GKMKNIOF_00429 2.84e-108 - - - K - - - FR47-like protein
GKMKNIOF_00430 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GKMKNIOF_00431 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKMKNIOF_00432 3.91e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKMKNIOF_00433 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKMKNIOF_00434 2.75e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKMKNIOF_00435 1.61e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
GKMKNIOF_00436 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GKMKNIOF_00437 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_00438 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_00439 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GKMKNIOF_00440 4.16e-51 ynzC - - S - - - UPF0291 protein
GKMKNIOF_00441 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKMKNIOF_00442 7.18e-187 - - - E - - - GDSL-like Lipase/Acylhydrolase family
GKMKNIOF_00443 1.15e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GKMKNIOF_00444 4.96e-270 - - - S - - - SLAP domain
GKMKNIOF_00445 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKMKNIOF_00446 1.02e-299 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GKMKNIOF_00447 1.59e-61 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GKMKNIOF_00449 9.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKMKNIOF_00450 2.23e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKMKNIOF_00451 5.6e-129 - - - M - - - ErfK YbiS YcfS YnhG
GKMKNIOF_00452 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GKMKNIOF_00453 6.03e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GKMKNIOF_00454 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
GKMKNIOF_00456 0.0 - - - - - - - -
GKMKNIOF_00457 0.0 ycaM - - E - - - amino acid
GKMKNIOF_00458 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
GKMKNIOF_00459 7.65e-101 - - - K - - - MerR HTH family regulatory protein
GKMKNIOF_00460 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GKMKNIOF_00461 4.64e-63 - - - S - - - Domain of unknown function (DUF4811)
GKMKNIOF_00462 5.13e-70 - - - - - - - -
GKMKNIOF_00464 3.64e-218 - - - D - - - ftsk spoiiie
GKMKNIOF_00467 2.45e-64 - - - - - - - -
GKMKNIOF_00468 4.62e-101 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GKMKNIOF_00470 1.81e-22 repA - - S - - - Replication initiator protein A (RepA) N-terminus
GKMKNIOF_00471 6.76e-80 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GKMKNIOF_00472 1.77e-194 - - - I - - - alpha/beta hydrolase fold
GKMKNIOF_00473 3.2e-143 - - - S - - - SNARE associated Golgi protein
GKMKNIOF_00474 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKMKNIOF_00475 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKMKNIOF_00476 4.98e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKMKNIOF_00477 1.44e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKMKNIOF_00478 9.06e-184 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKMKNIOF_00479 1.38e-165 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKMKNIOF_00480 7.46e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
GKMKNIOF_00481 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GKMKNIOF_00482 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GKMKNIOF_00483 3.44e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GKMKNIOF_00484 3.22e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKMKNIOF_00485 2.12e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKMKNIOF_00486 4.42e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GKMKNIOF_00487 1.27e-311 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GKMKNIOF_00488 1.64e-59 yitW - - S - - - Iron-sulfur cluster assembly protein
GKMKNIOF_00489 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GKMKNIOF_00490 6.98e-78 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GKMKNIOF_00491 1.39e-224 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKMKNIOF_00492 6.22e-232 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GKMKNIOF_00493 4.43e-179 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GKMKNIOF_00494 1.18e-95 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
GKMKNIOF_00496 5.89e-316 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
GKMKNIOF_00497 1.22e-195 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_00498 4.48e-174 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKMKNIOF_00499 7.05e-146 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_00500 1.58e-10 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_00501 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
GKMKNIOF_00502 2.46e-48 - - - - - - - -
GKMKNIOF_00504 1.46e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GKMKNIOF_00505 4.6e-113 - - - K - - - GNAT family
GKMKNIOF_00506 5.25e-258 XK27_00915 - - C - - - Luciferase-like monooxygenase
GKMKNIOF_00507 4.45e-156 rbtT - - P ko:K13021 - ko00000,ko02000 Major Facilitator Superfamily
GKMKNIOF_00508 2.81e-76 - - - EGP - - - Major Facilitator
GKMKNIOF_00509 1.08e-161 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_00510 1.48e-139 - - - EGP - - - Major Facilitator
GKMKNIOF_00511 9.16e-301 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKMKNIOF_00512 7.84e-95 - - - EGP - - - Major Facilitator
GKMKNIOF_00513 2.58e-45 - - - - - - - -
GKMKNIOF_00515 3.3e-42 - - - - - - - -
GKMKNIOF_00516 1.62e-96 - - - M - - - LysM domain
GKMKNIOF_00517 5.75e-152 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GKMKNIOF_00518 5.29e-256 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKMKNIOF_00519 2.25e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKMKNIOF_00520 4.58e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GKMKNIOF_00521 1.15e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKMKNIOF_00522 2.43e-118 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKMKNIOF_00523 1.16e-13 - - - L - - - Psort location Cytoplasmic, score
GKMKNIOF_00524 1.19e-29 - - - - - - - -
GKMKNIOF_00525 7.91e-102 - - - - - - - -
GKMKNIOF_00526 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
GKMKNIOF_00527 2.94e-250 - - - S - - - Putative peptidoglycan binding domain
GKMKNIOF_00528 2.61e-23 - - - - - - - -
GKMKNIOF_00529 1.05e-119 - - - S - - - membrane
GKMKNIOF_00530 5.3e-92 - - - K - - - LytTr DNA-binding domain
GKMKNIOF_00531 6.93e-34 - - - S - - - Sugar efflux transporter for intercellular exchange
GKMKNIOF_00532 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GKMKNIOF_00533 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKMKNIOF_00534 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
GKMKNIOF_00535 1.5e-90 - - - - - - - -
GKMKNIOF_00536 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
GKMKNIOF_00537 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKMKNIOF_00538 1.28e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKMKNIOF_00539 8.73e-187 - - - S - - - haloacid dehalogenase-like hydrolase
GKMKNIOF_00540 9.01e-287 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_00541 1.92e-80 yneE - - K - - - Transcriptional regulator
GKMKNIOF_00542 2.18e-122 yneE - - K - - - Transcriptional regulator
GKMKNIOF_00543 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GKMKNIOF_00544 5.05e-11 - - - - - - - -
GKMKNIOF_00545 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GKMKNIOF_00546 2.29e-112 - - - - - - - -
GKMKNIOF_00547 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKMKNIOF_00548 1.24e-232 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKMKNIOF_00549 5.07e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKMKNIOF_00550 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
GKMKNIOF_00551 2.62e-199 epsV - - S - - - glycosyl transferase family 2
GKMKNIOF_00552 5.29e-164 - - - S - - - Alpha/beta hydrolase family
GKMKNIOF_00553 6.06e-54 yabO - - J - - - S4 domain protein
GKMKNIOF_00554 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKMKNIOF_00555 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKMKNIOF_00556 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKMKNIOF_00557 1.23e-166 - - - S - - - (CBS) domain
GKMKNIOF_00558 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GKMKNIOF_00559 9.79e-181 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
GKMKNIOF_00560 2.75e-143 - - - G - - - phosphoglycerate mutase
GKMKNIOF_00561 1.45e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GKMKNIOF_00562 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GKMKNIOF_00563 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_00564 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKMKNIOF_00565 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GKMKNIOF_00566 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKMKNIOF_00567 1.83e-190 yxeH - - S - - - hydrolase
GKMKNIOF_00568 1.26e-40 - - - S - - - reductase
GKMKNIOF_00569 2.98e-50 - - - S - - - reductase
GKMKNIOF_00570 1.19e-43 - - - S - - - reductase
GKMKNIOF_00571 4.66e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKMKNIOF_00572 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
GKMKNIOF_00573 1.01e-33 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKMKNIOF_00574 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00575 6.32e-157 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKMKNIOF_00576 2.25e-30 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
GKMKNIOF_00577 1.81e-190 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKMKNIOF_00578 9.29e-51 - - - S - - - Protein of unknown function (DUF3021)
GKMKNIOF_00579 8.95e-70 - - - K - - - LytTr DNA-binding domain
GKMKNIOF_00582 6.49e-137 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_00583 2.82e-125 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_00584 4.78e-261 - - - S - - - Domain of unknown function (DUF389)
GKMKNIOF_00585 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GKMKNIOF_00586 2.2e-79 lysM - - M - - - LysM domain
GKMKNIOF_00587 7.62e-223 - - - - - - - -
GKMKNIOF_00588 6.74e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GKMKNIOF_00589 1.27e-58 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GKMKNIOF_00590 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKMKNIOF_00591 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKMKNIOF_00592 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GKMKNIOF_00593 9.71e-47 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKMKNIOF_00594 5.3e-32 - - - - - - - -
GKMKNIOF_00595 4.51e-60 - - - M - - - Glycosyl hydrolases family 25
GKMKNIOF_00596 1.54e-112 - - - M - - - Glycosyl hydrolases family 25
GKMKNIOF_00597 1.76e-38 - - - - - - - -
GKMKNIOF_00598 6.31e-27 - - - - - - - -
GKMKNIOF_00601 2.12e-27 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GKMKNIOF_00602 1.28e-54 - - - - - - - -
GKMKNIOF_00608 8.2e-07 - - - - - - - -
GKMKNIOF_00610 3.71e-154 - - - S - - - Baseplate J-like protein
GKMKNIOF_00611 2.37e-43 - - - - - - - -
GKMKNIOF_00612 4.6e-63 - - - - - - - -
GKMKNIOF_00613 1.11e-128 - - - - - - - -
GKMKNIOF_00614 6.91e-61 - - - - - - - -
GKMKNIOF_00615 1.06e-69 - - - M - - - LysM domain
GKMKNIOF_00616 0.0 - - - L - - - Phage tail tape measure protein TP901
GKMKNIOF_00619 1.33e-73 - - - - - - - -
GKMKNIOF_00620 7.86e-194 - - - S - - - Protein of unknown function (DUF3383)
GKMKNIOF_00621 7.95e-69 - - - - - - - -
GKMKNIOF_00622 1.8e-59 - - - - - - - -
GKMKNIOF_00623 2.18e-96 - - - - - - - -
GKMKNIOF_00625 1.83e-181 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
GKMKNIOF_00626 5.09e-76 - - - - - - - -
GKMKNIOF_00627 2.77e-137 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GKMKNIOF_00628 1.14e-16 - - - S - - - Lysin motif
GKMKNIOF_00629 5.89e-127 - - - S - - - Phage Mu protein F like protein
GKMKNIOF_00630 2.28e-178 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GKMKNIOF_00631 1.1e-235 - - - S - - - Terminase-like family
GKMKNIOF_00632 1.22e-24 - - - S - - - Terminase-like family
GKMKNIOF_00633 3.14e-48 - - - L ko:K07474 - ko00000 Terminase small subunit
GKMKNIOF_00634 7.69e-16 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
GKMKNIOF_00635 8.27e-46 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
GKMKNIOF_00644 1.08e-10 - - - - - - - -
GKMKNIOF_00645 5.99e-52 - - - L - - - Endodeoxyribonuclease RusA
GKMKNIOF_00651 8.93e-64 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GKMKNIOF_00652 3.2e-41 - - - S - - - Conserved phage C-terminus (Phg_2220_C)
GKMKNIOF_00653 1.11e-70 - - - S - - - Protein of unknown function (DUF1071)
GKMKNIOF_00657 2.36e-08 - - - K - - - DNA-binding protein
GKMKNIOF_00663 5.23e-122 - - - S - - - AntA/AntB antirepressor
GKMKNIOF_00664 8.72e-07 - - - - - - - -
GKMKNIOF_00669 1.71e-102 - - - S - - - DNA binding
GKMKNIOF_00670 1.21e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_00671 7e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
GKMKNIOF_00677 1.09e-226 - - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_00678 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKMKNIOF_00679 6.87e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKMKNIOF_00680 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GKMKNIOF_00681 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKMKNIOF_00682 6.02e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKMKNIOF_00683 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GKMKNIOF_00684 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKMKNIOF_00685 1.67e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKMKNIOF_00686 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKMKNIOF_00687 1.61e-64 ylxQ - - J - - - ribosomal protein
GKMKNIOF_00688 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GKMKNIOF_00689 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GKMKNIOF_00690 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GKMKNIOF_00691 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKMKNIOF_00692 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKMKNIOF_00693 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GKMKNIOF_00694 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GKMKNIOF_00695 6.38e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKMKNIOF_00696 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKMKNIOF_00697 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GKMKNIOF_00698 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKMKNIOF_00699 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GKMKNIOF_00700 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GKMKNIOF_00701 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GKMKNIOF_00702 8.61e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GKMKNIOF_00703 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GKMKNIOF_00704 2.64e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKMKNIOF_00705 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKMKNIOF_00706 7.82e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKMKNIOF_00707 7.1e-252 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKMKNIOF_00708 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKMKNIOF_00709 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_00710 1.19e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKMKNIOF_00711 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GKMKNIOF_00712 6.67e-115 - - - G - - - Peptidase_C39 like family
GKMKNIOF_00713 2.16e-207 - - - M - - - NlpC/P60 family
GKMKNIOF_00714 1.93e-32 - - - G - - - Peptidase_C39 like family
GKMKNIOF_00715 3.43e-79 - - - C - - - 2Fe-2S iron-sulfur cluster binding domain
GKMKNIOF_00716 1.53e-189 - 5.2.1.13 - Q ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
GKMKNIOF_00717 7.13e-67 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
GKMKNIOF_00718 5.71e-230 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GKMKNIOF_00719 1.39e-143 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKMKNIOF_00722 8.52e-25 lysM - - M - - - LysM domain
GKMKNIOF_00723 1.05e-192 - - - S - - - COG0433 Predicted ATPase
GKMKNIOF_00727 1.64e-98 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
GKMKNIOF_00728 4.47e-26 - - - - - - - -
GKMKNIOF_00730 1.41e-232 - - - M - - - Glycosyl hydrolases family 25
GKMKNIOF_00731 1.66e-36 - - - - - - - -
GKMKNIOF_00732 1.28e-22 - - - - - - - -
GKMKNIOF_00735 9.12e-09 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GKMKNIOF_00743 4.01e-161 - - - S - - - Baseplate J-like protein
GKMKNIOF_00744 1.32e-42 - - - - - - - -
GKMKNIOF_00745 1.62e-56 - - - - - - - -
GKMKNIOF_00746 5.89e-141 - - - - - - - -
GKMKNIOF_00747 3.78e-49 - - - - - - - -
GKMKNIOF_00749 4.84e-286 - - - L - - - Phage tail tape measure protein TP901
GKMKNIOF_00752 6.45e-39 - - - - - - - -
GKMKNIOF_00753 4.55e-127 - - - S - - - Protein of unknown function (DUF3383)
GKMKNIOF_00755 7.92e-34 - - - - - - - -
GKMKNIOF_00756 2.42e-23 - - - - - - - -
GKMKNIOF_00758 2.06e-118 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
GKMKNIOF_00760 2.19e-83 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GKMKNIOF_00762 7.9e-55 - - - S - - - Phage Mu protein F like protein
GKMKNIOF_00763 1.36e-164 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GKMKNIOF_00764 2.38e-251 - - - S - - - Terminase-like family
GKMKNIOF_00765 2.21e-13 - - - L ko:K07474 - ko00000 Terminase small subunit
GKMKNIOF_00771 1.32e-273 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
GKMKNIOF_00773 5.26e-53 - - - S - - - VRR_NUC
GKMKNIOF_00775 1.36e-82 - - - S - - - ORF6C domain
GKMKNIOF_00780 3.3e-139 - - - L - - - Helix-turn-helix domain
GKMKNIOF_00781 5.44e-168 - - - S - - - ERF superfamily
GKMKNIOF_00782 7.8e-162 - - - S - - - Protein of unknown function (DUF1351)
GKMKNIOF_00783 1.07e-58 - - - - - - - -
GKMKNIOF_00785 2.12e-24 - - - - - - - -
GKMKNIOF_00786 4.49e-42 - - - S - - - Helix-turn-helix domain
GKMKNIOF_00792 2.79e-121 - - - S - - - DNA binding
GKMKNIOF_00793 7.6e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_00794 1.66e-30 - - - K - - - Cro/C1-type HTH DNA-binding domain
GKMKNIOF_00795 8.24e-15 - - - - - - - -
GKMKNIOF_00798 2.22e-113 - - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_00799 4.29e-54 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
GKMKNIOF_00804 6.48e-10 - - - M - - - oxidoreductase activity
GKMKNIOF_00806 3.69e-20 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GKMKNIOF_00807 2.48e-15 - - - S - - - SLAP domain
GKMKNIOF_00811 2.59e-10 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKMKNIOF_00819 2.38e-32 - - - S - - - Domain of unknown function (DUF771)
GKMKNIOF_00820 7.62e-41 - - - K - - - Helix-turn-helix domain
GKMKNIOF_00821 4.74e-30 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
GKMKNIOF_00822 6.66e-31 - - - K - - - Helix-turn-helix domain
GKMKNIOF_00824 2.63e-194 int3 - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_00826 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKMKNIOF_00827 2.42e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GKMKNIOF_00828 3.69e-30 - - - - - - - -
GKMKNIOF_00829 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GKMKNIOF_00830 1.68e-55 - - - - - - - -
GKMKNIOF_00831 8.19e-91 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
GKMKNIOF_00832 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GKMKNIOF_00833 1.72e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GKMKNIOF_00834 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GKMKNIOF_00835 3.43e-70 yebC - - K - - - Transcriptional regulatory protein
GKMKNIOF_00836 3.56e-141 - - - S - - - Fic/DOC family
GKMKNIOF_00837 1.72e-22 - - - L - - - Psort location Cytoplasmic, score
GKMKNIOF_00838 1.02e-34 - - - S - - - Psort location Cytoplasmic, score 8.87
GKMKNIOF_00840 1.62e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKMKNIOF_00842 3.76e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_00843 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
GKMKNIOF_00844 2.16e-79 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKMKNIOF_00845 6.73e-78 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKMKNIOF_00846 2.45e-47 - - - L - - - Transposase and inactivated derivatives, IS30 family
GKMKNIOF_00847 1.75e-211 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GKMKNIOF_00848 0.0 - - - L - - - Nuclease-related domain
GKMKNIOF_00849 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKMKNIOF_00850 2.31e-148 - - - S - - - repeat protein
GKMKNIOF_00851 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
GKMKNIOF_00852 4.47e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKMKNIOF_00853 9.98e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GKMKNIOF_00854 1.62e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKMKNIOF_00855 2.05e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKMKNIOF_00856 1.22e-55 - - - - - - - -
GKMKNIOF_00857 5.18e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GKMKNIOF_00858 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
GKMKNIOF_00859 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKMKNIOF_00860 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GKMKNIOF_00861 4.01e-192 ylmH - - S - - - S4 domain protein
GKMKNIOF_00862 2.42e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
GKMKNIOF_00863 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKMKNIOF_00864 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKMKNIOF_00865 3.3e-315 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKMKNIOF_00866 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKMKNIOF_00867 3.88e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKMKNIOF_00868 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKMKNIOF_00869 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKMKNIOF_00870 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKMKNIOF_00871 6.55e-72 ftsL - - D - - - Cell division protein FtsL
GKMKNIOF_00872 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKMKNIOF_00873 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GKMKNIOF_00874 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
GKMKNIOF_00875 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
GKMKNIOF_00876 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
GKMKNIOF_00877 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GKMKNIOF_00878 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GKMKNIOF_00879 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
GKMKNIOF_00880 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
GKMKNIOF_00881 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKMKNIOF_00882 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKMKNIOF_00883 2.91e-67 - - - - - - - -
GKMKNIOF_00884 3.02e-166 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GKMKNIOF_00885 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKMKNIOF_00886 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_00887 8.53e-59 - - - - - - - -
GKMKNIOF_00888 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
GKMKNIOF_00889 4.08e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GKMKNIOF_00890 1.06e-86 - - - S - - - GtrA-like protein
GKMKNIOF_00891 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_00892 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKMKNIOF_00893 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GKMKNIOF_00894 3.48e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKMKNIOF_00895 3.52e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKMKNIOF_00896 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKMKNIOF_00897 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKMKNIOF_00898 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
GKMKNIOF_00899 1.47e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GKMKNIOF_00900 1.35e-56 - - - - - - - -
GKMKNIOF_00901 9.45e-104 uspA - - T - - - universal stress protein
GKMKNIOF_00902 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GKMKNIOF_00903 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
GKMKNIOF_00904 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GKMKNIOF_00905 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GKMKNIOF_00906 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
GKMKNIOF_00907 4.95e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GKMKNIOF_00908 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKMKNIOF_00909 1.48e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKMKNIOF_00910 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKMKNIOF_00911 6.55e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKMKNIOF_00912 2.48e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKMKNIOF_00913 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKMKNIOF_00914 5.87e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GKMKNIOF_00915 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKMKNIOF_00916 1.66e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKMKNIOF_00917 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKMKNIOF_00918 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKMKNIOF_00919 7.02e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GKMKNIOF_00920 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
GKMKNIOF_00923 7.95e-250 ampC - - V - - - Beta-lactamase
GKMKNIOF_00924 3.26e-274 - - - EGP - - - Major Facilitator
GKMKNIOF_00925 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GKMKNIOF_00926 5.3e-137 vanZ - - V - - - VanZ like family
GKMKNIOF_00927 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKMKNIOF_00928 0.0 yclK - - T - - - Histidine kinase
GKMKNIOF_00929 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
GKMKNIOF_00930 9.01e-90 - - - S - - - SdpI/YhfL protein family
GKMKNIOF_00931 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKMKNIOF_00932 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GKMKNIOF_00933 1.21e-127 - - - M - - - Protein of unknown function (DUF3737)
GKMKNIOF_00935 1e-22 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
GKMKNIOF_00936 5.44e-299 - - - V - - - N-6 DNA Methylase
GKMKNIOF_00937 3.48e-105 - - - V - - - Type I restriction modification DNA specificity domain
GKMKNIOF_00938 6.8e-48 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GKMKNIOF_00939 2.73e-21 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GKMKNIOF_00940 2.82e-17 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GKMKNIOF_00941 2.15e-63 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00942 0.0 - - - L - - - PLD-like domain
GKMKNIOF_00943 5.97e-55 - - - S - - - SnoaL-like domain
GKMKNIOF_00944 6.13e-70 - - - K - - - sequence-specific DNA binding
GKMKNIOF_00945 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
GKMKNIOF_00946 5.51e-35 - - - - - - - -
GKMKNIOF_00947 3.05e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKMKNIOF_00948 3.68e-176 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKMKNIOF_00950 1.23e-175 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00951 2.24e-71 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GKMKNIOF_00952 8.41e-42 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKMKNIOF_00953 2.52e-06 - - - D - - - Domain of Unknown Function (DUF1542)
GKMKNIOF_00954 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
GKMKNIOF_00955 4.97e-45 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
GKMKNIOF_00957 6.24e-210 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_00958 1.96e-127 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GKMKNIOF_00959 8.97e-47 - - - - - - - -
GKMKNIOF_00960 5.94e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GKMKNIOF_00961 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
GKMKNIOF_00962 1.98e-44 - - - - - - - -
GKMKNIOF_00963 4.83e-107 ybbB - - S - - - Protein of unknown function (DUF1211)
GKMKNIOF_00964 1.53e-142 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GKMKNIOF_00965 6.21e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
GKMKNIOF_00966 1.63e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKMKNIOF_00968 4.61e-37 - - - S - - - Enterocin A Immunity
GKMKNIOF_00971 1.47e-91 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
GKMKNIOF_00972 7.27e-42 - - - - - - - -
GKMKNIOF_00973 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GKMKNIOF_00974 3.55e-28 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GKMKNIOF_00975 3.34e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GKMKNIOF_00976 4.14e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKMKNIOF_00977 0.0 qacA - - EGP - - - Major Facilitator
GKMKNIOF_00978 3.56e-47 - - - - - - - -
GKMKNIOF_00979 4.13e-83 - - - - - - - -
GKMKNIOF_00982 1.51e-159 - - - - - - - -
GKMKNIOF_00983 4.83e-136 pncA - - Q - - - Isochorismatase family
GKMKNIOF_00984 1.24e-08 - - - - - - - -
GKMKNIOF_00985 1.73e-48 - - - - - - - -
GKMKNIOF_00986 1.86e-91 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_00987 1.28e-226 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_00988 4.77e-248 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GKMKNIOF_00989 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GKMKNIOF_00990 3.73e-72 - - - S - - - Domain of unknown function (DUF4767)
GKMKNIOF_00991 1.43e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKMKNIOF_00992 1.23e-187 - - - S - - - Uncharacterised protein, DegV family COG1307
GKMKNIOF_00993 1.94e-130 - - - I - - - PAP2 superfamily
GKMKNIOF_00994 1.03e-141 - - - L - - - COG3547 Transposase and inactivated derivatives
GKMKNIOF_00995 8.06e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKMKNIOF_00996 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKMKNIOF_00997 7.31e-181 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
GKMKNIOF_00998 1.42e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKMKNIOF_00999 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKMKNIOF_01000 1.23e-194 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GKMKNIOF_01001 1.73e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKMKNIOF_01002 3.71e-199 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKMKNIOF_01003 4.11e-124 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GKMKNIOF_01004 7.2e-49 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GKMKNIOF_01005 3.67e-88 - - - P - - - NhaP-type Na H and K H
GKMKNIOF_01006 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
GKMKNIOF_01007 8.83e-187 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
GKMKNIOF_01008 1.8e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GKMKNIOF_01009 5.13e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKMKNIOF_01010 2.81e-203 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKMKNIOF_01011 2.78e-131 - - - M - - - hydrolase, family 25
GKMKNIOF_01022 1.35e-204 - - - S - - - Phage minor structural protein
GKMKNIOF_01024 1.32e-219 - - - D - - - domain protein
GKMKNIOF_01029 3.91e-38 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKMKNIOF_01032 1.9e-98 - - - S - - - Phage capsid family
GKMKNIOF_01033 2.11e-56 - - - S - - - Clp protease
GKMKNIOF_01034 6.21e-116 - - - S - - - Phage portal protein
GKMKNIOF_01036 4.84e-221 terL - - S - - - overlaps another CDS with the same product name
GKMKNIOF_01053 2.38e-28 - - - L - - - Psort location Cytoplasmic, score
GKMKNIOF_01060 2.97e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_01061 1.57e-87 - - - K - - - Peptidase S24-like
GKMKNIOF_01062 4.09e-61 - - - S - - - Short C-terminal domain
GKMKNIOF_01065 1.22e-129 - - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_01066 2.75e-111 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
GKMKNIOF_01067 1.11e-41 yagE - - E - - - Amino acid permease
GKMKNIOF_01068 2.25e-125 yagE - - E - - - Amino acid permease
GKMKNIOF_01069 2.81e-189 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
GKMKNIOF_01070 4.87e-187 - - - F - - - Phosphorylase superfamily
GKMKNIOF_01071 6.97e-53 - - - F - - - NUDIX domain
GKMKNIOF_01072 2.14e-104 - - - S - - - AAA domain
GKMKNIOF_01073 2.24e-29 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKMKNIOF_01074 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKMKNIOF_01075 1.93e-56 - - - L - - - Transposase DDE domain
GKMKNIOF_01076 4.4e-165 - - - S - - - PAS domain
GKMKNIOF_01078 2.62e-69 - - - - - - - -
GKMKNIOF_01079 1.02e-75 - - - - - - - -
GKMKNIOF_01080 4.53e-11 - - - - - - - -
GKMKNIOF_01081 1.5e-93 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKMKNIOF_01082 9e-104 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKMKNIOF_01083 1.44e-164 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKMKNIOF_01084 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKMKNIOF_01085 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GKMKNIOF_01089 2.76e-112 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKMKNIOF_01090 4.31e-175 - - - - - - - -
GKMKNIOF_01091 5.53e-147 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GKMKNIOF_01092 6.61e-186 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_01093 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GKMKNIOF_01094 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GKMKNIOF_01095 0.0 qacA - - EGP - - - Major Facilitator
GKMKNIOF_01100 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
GKMKNIOF_01101 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKMKNIOF_01102 1.01e-256 flp - - V - - - Beta-lactamase
GKMKNIOF_01103 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GKMKNIOF_01104 9.92e-187 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GKMKNIOF_01105 1.46e-75 - - - - - - - -
GKMKNIOF_01106 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKMKNIOF_01107 5.58e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GKMKNIOF_01108 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKMKNIOF_01109 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKMKNIOF_01110 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKMKNIOF_01111 6.25e-268 camS - - S - - - sex pheromone
GKMKNIOF_01112 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKMKNIOF_01113 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GKMKNIOF_01114 2.26e-118 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GKMKNIOF_01116 2.62e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GKMKNIOF_01117 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GKMKNIOF_01118 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKMKNIOF_01119 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKMKNIOF_01120 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKMKNIOF_01121 9.83e-261 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_01122 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKMKNIOF_01123 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKMKNIOF_01124 1.03e-261 - - - M - - - Glycosyl transferases group 1
GKMKNIOF_01125 3.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKMKNIOF_01126 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
GKMKNIOF_01127 1.87e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
GKMKNIOF_01128 2.17e-232 - - - - - - - -
GKMKNIOF_01129 1.15e-54 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_01130 7.83e-303 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_01133 4.41e-305 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
GKMKNIOF_01134 1.18e-13 - - - - - - - -
GKMKNIOF_01135 6.39e-32 - - - S - - - transposase or invertase
GKMKNIOF_01136 1.36e-308 slpX - - S - - - SLAP domain
GKMKNIOF_01137 1.43e-186 - - - K - - - SIS domain
GKMKNIOF_01138 3.01e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GKMKNIOF_01139 1.03e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GKMKNIOF_01140 1.93e-266 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKMKNIOF_01142 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKMKNIOF_01144 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKMKNIOF_01145 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
GKMKNIOF_01146 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
GKMKNIOF_01147 8.92e-136 - - - G - - - Phosphoglycerate mutase family
GKMKNIOF_01148 5.68e-211 - - - D - - - nuclear chromosome segregation
GKMKNIOF_01149 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKMKNIOF_01150 2.35e-117 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GKMKNIOF_01151 1.41e-37 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_01152 1.19e-19 - - - S ko:K07133 - ko00000 cog cog1373
GKMKNIOF_01153 4.06e-109 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GKMKNIOF_01154 0.0 XK27_08315 - - M - - - Sulfatase
GKMKNIOF_01155 1.03e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKMKNIOF_01156 2.92e-258 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKMKNIOF_01157 5.18e-128 - - - G - - - Aldose 1-epimerase
GKMKNIOF_01158 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKMKNIOF_01159 1.72e-149 - - - - - - - -
GKMKNIOF_01160 1.98e-168 - - - - - - - -
GKMKNIOF_01161 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GKMKNIOF_01162 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKMKNIOF_01163 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GKMKNIOF_01164 7.32e-232 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GKMKNIOF_01165 2.09e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKMKNIOF_01167 6.62e-161 - - - S - - - SLAP domain
GKMKNIOF_01169 2.85e-54 - - - - - - - -
GKMKNIOF_01170 3.6e-101 - - - K - - - DNA-templated transcription, initiation
GKMKNIOF_01172 4.56e-191 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_01174 6.35e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_01175 8.38e-140 - - - S - - - SLAP domain
GKMKNIOF_01176 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
GKMKNIOF_01177 1.21e-40 - - - - - - - -
GKMKNIOF_01178 2.77e-25 - - - - - - - -
GKMKNIOF_01179 3.61e-60 - - - - - - - -
GKMKNIOF_01180 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKMKNIOF_01182 3.75e-48 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_01183 6.55e-97 - - - - - - - -
GKMKNIOF_01184 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GKMKNIOF_01185 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GKMKNIOF_01186 2.31e-277 yqjV - - EGP - - - Major Facilitator Superfamily
GKMKNIOF_01187 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GKMKNIOF_01188 3.41e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
GKMKNIOF_01189 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKMKNIOF_01190 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GKMKNIOF_01191 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GKMKNIOF_01192 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKMKNIOF_01193 0.0 - - - S - - - Calcineurin-like phosphoesterase
GKMKNIOF_01194 5.18e-109 - - - - - - - -
GKMKNIOF_01195 6.82e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GKMKNIOF_01196 1.83e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_01197 1.02e-154 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_01198 6.8e-175 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GKMKNIOF_01199 2.58e-203 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
GKMKNIOF_01200 9.29e-111 usp5 - - T - - - universal stress protein
GKMKNIOF_01201 1.24e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKMKNIOF_01202 3.77e-113 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKMKNIOF_01203 4.83e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GKMKNIOF_01205 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GKMKNIOF_01206 4.17e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKMKNIOF_01207 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_01208 6.79e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GKMKNIOF_01209 8.74e-62 - - - - - - - -
GKMKNIOF_01210 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GKMKNIOF_01211 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKMKNIOF_01212 1.02e-29 - - - S - - - Alpha beta hydrolase
GKMKNIOF_01213 2.48e-80 - - - S - - - Alpha beta hydrolase
GKMKNIOF_01214 8.51e-50 - - - - - - - -
GKMKNIOF_01215 4.3e-66 - - - - - - - -
GKMKNIOF_01216 9.38e-189 supH - - S - - - haloacid dehalogenase-like hydrolase
GKMKNIOF_01217 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_01218 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_01219 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GKMKNIOF_01220 1.23e-227 lipA - - I - - - Carboxylesterase family
GKMKNIOF_01222 2.73e-268 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKMKNIOF_01223 8.57e-202 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GKMKNIOF_01224 0.0 - - - S - - - Predicted membrane protein (DUF2207)
GKMKNIOF_01225 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GKMKNIOF_01227 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GKMKNIOF_01228 5.24e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKMKNIOF_01229 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GKMKNIOF_01230 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GKMKNIOF_01231 2.14e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKMKNIOF_01232 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKMKNIOF_01233 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GKMKNIOF_01234 2.78e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKMKNIOF_01235 7.19e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKMKNIOF_01236 1.97e-248 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKMKNIOF_01237 1.53e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKMKNIOF_01238 6.44e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKMKNIOF_01239 7.22e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GKMKNIOF_01240 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GKMKNIOF_01241 2.19e-100 - - - S - - - ASCH
GKMKNIOF_01242 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GKMKNIOF_01243 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKMKNIOF_01244 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKMKNIOF_01245 4.41e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKMKNIOF_01246 1.06e-308 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKMKNIOF_01247 1.98e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GKMKNIOF_01248 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKMKNIOF_01249 1.71e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKMKNIOF_01250 4.33e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GKMKNIOF_01251 3.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GKMKNIOF_01252 2.2e-41 - - - - - - - -
GKMKNIOF_01253 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GKMKNIOF_01254 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
GKMKNIOF_01255 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GKMKNIOF_01256 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKMKNIOF_01257 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKMKNIOF_01258 1.04e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKMKNIOF_01259 7.02e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKMKNIOF_01260 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKMKNIOF_01261 1.53e-218 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01262 3.06e-181 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_01263 3.82e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKMKNIOF_01264 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
GKMKNIOF_01265 1.64e-45 - - - - - - - -
GKMKNIOF_01266 6.11e-66 - - - S - - - Protein of unknown function (DUF3021)
GKMKNIOF_01267 2.64e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GKMKNIOF_01268 1.56e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKMKNIOF_01269 1.49e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
GKMKNIOF_01270 1.56e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
GKMKNIOF_01271 1.46e-206 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GKMKNIOF_01272 2.42e-33 - - - - - - - -
GKMKNIOF_01273 8.07e-163 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKMKNIOF_01274 5.69e-235 - - - S - - - AAA domain
GKMKNIOF_01275 8.69e-66 - - - - - - - -
GKMKNIOF_01276 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GKMKNIOF_01277 1.11e-69 - - - - - - - -
GKMKNIOF_01278 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GKMKNIOF_01279 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKMKNIOF_01280 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKMKNIOF_01281 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKMKNIOF_01282 2.45e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKMKNIOF_01283 2.69e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKMKNIOF_01284 1.55e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GKMKNIOF_01285 1.19e-45 - - - - - - - -
GKMKNIOF_01286 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKMKNIOF_01287 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKMKNIOF_01288 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKMKNIOF_01289 5e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GKMKNIOF_01290 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKMKNIOF_01291 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKMKNIOF_01292 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKMKNIOF_01293 1.13e-210 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKMKNIOF_01294 3.52e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GKMKNIOF_01295 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKMKNIOF_01296 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKMKNIOF_01297 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GKMKNIOF_01298 7.66e-116 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_01300 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKMKNIOF_01301 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKMKNIOF_01302 9.32e-189 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
GKMKNIOF_01303 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GKMKNIOF_01304 6.15e-36 - - - - - - - -
GKMKNIOF_01305 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKMKNIOF_01306 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKMKNIOF_01307 1.12e-136 - - - M - - - family 8
GKMKNIOF_01308 1.15e-47 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
GKMKNIOF_01309 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKMKNIOF_01310 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKMKNIOF_01311 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
GKMKNIOF_01312 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKMKNIOF_01313 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
GKMKNIOF_01314 8.4e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKMKNIOF_01315 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
GKMKNIOF_01316 3.05e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKMKNIOF_01317 4.27e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GKMKNIOF_01318 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
GKMKNIOF_01319 3.69e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GKMKNIOF_01320 3.93e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GKMKNIOF_01321 5.79e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKMKNIOF_01322 1.28e-311 - - - L ko:K07484 - ko00000 Transposase IS66 family
GKMKNIOF_01323 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
GKMKNIOF_01324 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GKMKNIOF_01325 9.48e-31 - - - - - - - -
GKMKNIOF_01326 6.8e-52 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKMKNIOF_01327 6.43e-230 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKMKNIOF_01328 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKMKNIOF_01329 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GKMKNIOF_01330 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKMKNIOF_01331 3.52e-299 - - - L ko:K06919 - ko00000 D5 N terminal like
GKMKNIOF_01332 3.3e-38 - - - K - - - Transcriptional regulator
GKMKNIOF_01333 4.22e-288 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_01334 4.06e-39 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_01335 1.31e-56 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKMKNIOF_01336 8.72e-258 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKMKNIOF_01337 1.04e-94 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKMKNIOF_01338 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKMKNIOF_01339 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKMKNIOF_01340 7.32e-157 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKMKNIOF_01341 6.74e-269 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKMKNIOF_01342 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
GKMKNIOF_01343 1.05e-115 - - - L - - - PFAM transposase, IS4 family protein
GKMKNIOF_01344 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKMKNIOF_01345 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKMKNIOF_01346 0.0 yhdP - - S - - - Transporter associated domain
GKMKNIOF_01347 2.14e-154 - - - C - - - nitroreductase
GKMKNIOF_01348 1.76e-52 - - - - - - - -
GKMKNIOF_01349 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GKMKNIOF_01350 1.52e-103 - - - - - - - -
GKMKNIOF_01351 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKMKNIOF_01352 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
GKMKNIOF_01353 7.44e-189 - - - S - - - hydrolase
GKMKNIOF_01354 1.85e-205 - - - S - - - Phospholipase, patatin family
GKMKNIOF_01355 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GKMKNIOF_01356 4.44e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GKMKNIOF_01357 2.9e-79 - - - S - - - Enterocin A Immunity
GKMKNIOF_01358 3.18e-198 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GKMKNIOF_01359 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
GKMKNIOF_01360 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GKMKNIOF_01361 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GKMKNIOF_01362 1.82e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKMKNIOF_01363 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKMKNIOF_01364 7.29e-209 - - - C - - - Domain of unknown function (DUF4931)
GKMKNIOF_01365 2.2e-308 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_01366 3.52e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GKMKNIOF_01367 2.09e-110 - - - - - - - -
GKMKNIOF_01368 1.04e-211 - - - S - - - Protein of unknown function (DUF2974)
GKMKNIOF_01369 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01370 4.29e-122 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01371 3.39e-187 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_01372 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01373 2.72e-60 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GKMKNIOF_01374 5.43e-50 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GKMKNIOF_01375 8.41e-314 - - - G - - - MFS/sugar transport protein
GKMKNIOF_01376 1.72e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GKMKNIOF_01377 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
GKMKNIOF_01378 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01379 7.27e-106 - - - K - - - Transcriptional regulator, MarR family
GKMKNIOF_01380 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_01381 1.07e-165 - - - F - - - glutamine amidotransferase
GKMKNIOF_01382 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
GKMKNIOF_01383 3.97e-33 steT - - E ko:K03294 - ko00000 amino acid
GKMKNIOF_01384 1.11e-256 steT - - E ko:K03294 - ko00000 amino acid
GKMKNIOF_01385 1.53e-176 - - - - - - - -
GKMKNIOF_01386 6.07e-223 ydhF - - S - - - Aldo keto reductase
GKMKNIOF_01387 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
GKMKNIOF_01388 6.67e-230 pepA - - E - - - M42 glutamyl aminopeptidase
GKMKNIOF_01390 3.31e-65 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GKMKNIOF_01392 2.86e-169 - - - L - - - Transposase and inactivated derivatives
GKMKNIOF_01393 4.63e-32 - - - - - - - -
GKMKNIOF_01394 6.72e-177 - - - EP - - - Plasmid replication protein
GKMKNIOF_01395 2.23e-99 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
GKMKNIOF_01396 3.83e-06 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKMKNIOF_01397 8.21e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKMKNIOF_01398 1.86e-117 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKMKNIOF_01399 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GKMKNIOF_01400 5.41e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GKMKNIOF_01401 2.16e-205 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKMKNIOF_01402 3.87e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKMKNIOF_01403 1.7e-117 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01404 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKMKNIOF_01405 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKMKNIOF_01406 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKMKNIOF_01407 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GKMKNIOF_01408 5.26e-171 - - - H - - - Aldolase/RraA
GKMKNIOF_01409 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKMKNIOF_01410 1.71e-196 - - - I - - - Alpha/beta hydrolase family
GKMKNIOF_01411 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GKMKNIOF_01412 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GKMKNIOF_01413 1.79e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GKMKNIOF_01414 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GKMKNIOF_01415 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
GKMKNIOF_01416 9.9e-30 - - - - - - - -
GKMKNIOF_01417 2.58e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GKMKNIOF_01418 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01419 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GKMKNIOF_01420 8.1e-87 - - - S - - - Domain of unknown function DUF1828
GKMKNIOF_01421 7.91e-14 - - - - - - - -
GKMKNIOF_01422 2.41e-66 - - - - - - - -
GKMKNIOF_01423 1.05e-226 citR - - K - - - Putative sugar-binding domain
GKMKNIOF_01424 9.28e-317 - - - S - - - Putative threonine/serine exporter
GKMKNIOF_01426 5.26e-15 - - - - - - - -
GKMKNIOF_01427 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKMKNIOF_01428 4.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GKMKNIOF_01429 3.8e-80 - - - - - - - -
GKMKNIOF_01430 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKMKNIOF_01431 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKMKNIOF_01432 7.1e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GKMKNIOF_01433 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKMKNIOF_01434 5.51e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKMKNIOF_01435 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKMKNIOF_01437 2.14e-48 - - - - - - - -
GKMKNIOF_01438 1.14e-208 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GKMKNIOF_01439 5.69e-179 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_01440 1.8e-43 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GKMKNIOF_01442 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKMKNIOF_01443 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKMKNIOF_01444 1.35e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKMKNIOF_01447 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
GKMKNIOF_01448 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GKMKNIOF_01449 6.45e-291 - - - E - - - amino acid
GKMKNIOF_01450 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GKMKNIOF_01452 1.95e-221 - - - V - - - HNH endonuclease
GKMKNIOF_01453 6.36e-173 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_01454 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKMKNIOF_01455 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKMKNIOF_01456 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKMKNIOF_01457 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
GKMKNIOF_01458 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKMKNIOF_01459 3.09e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_01460 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01461 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01462 1.96e-49 - - - - - - - -
GKMKNIOF_01463 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKMKNIOF_01464 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKMKNIOF_01465 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
GKMKNIOF_01466 1.97e-227 pbpX2 - - V - - - Beta-lactamase
GKMKNIOF_01467 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKMKNIOF_01468 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKMKNIOF_01469 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GKMKNIOF_01470 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKMKNIOF_01471 1.3e-26 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GKMKNIOF_01472 1.42e-58 - - - - - - - -
GKMKNIOF_01473 5.11e-265 - - - S - - - Membrane
GKMKNIOF_01474 3.41e-107 ykuL - - S - - - (CBS) domain
GKMKNIOF_01475 0.0 cadA - - P - - - P-type ATPase
GKMKNIOF_01476 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
GKMKNIOF_01477 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GKMKNIOF_01478 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
GKMKNIOF_01479 1.22e-67 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKMKNIOF_01480 3.7e-164 - - - S - - - SLAP domain
GKMKNIOF_01481 1.75e-120 - - - - - - - -
GKMKNIOF_01483 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
GKMKNIOF_01484 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GKMKNIOF_01485 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKMKNIOF_01486 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GKMKNIOF_01487 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKMKNIOF_01488 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GKMKNIOF_01489 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GKMKNIOF_01490 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
GKMKNIOF_01491 0.0 - - - S - - - membrane
GKMKNIOF_01492 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKMKNIOF_01493 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKMKNIOF_01494 7.92e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKMKNIOF_01495 9.32e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
GKMKNIOF_01496 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GKMKNIOF_01497 4.95e-89 yqhL - - P - - - Rhodanese-like protein
GKMKNIOF_01498 1.82e-214 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKMKNIOF_01499 2.05e-286 ynbB - - P - - - aluminum resistance
GKMKNIOF_01500 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GKMKNIOF_01501 9.64e-219 - - - - - - - -
GKMKNIOF_01502 1.21e-204 - - - - - - - -
GKMKNIOF_01504 3.96e-19 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GKMKNIOF_01505 1.92e-42 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GKMKNIOF_01507 6.79e-45 - - - - - - - -
GKMKNIOF_01508 3e-271 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_01509 1.22e-202 - - - S - - - interspecies interaction between organisms
GKMKNIOF_01510 1.28e-09 - - - S - - - PFAM HicB family
GKMKNIOF_01511 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_01513 1.19e-126 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_01514 0.0 - - - E - - - Amino acid permease
GKMKNIOF_01515 1.06e-256 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKMKNIOF_01516 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GKMKNIOF_01517 2.76e-83 - - - - - - - -
GKMKNIOF_01518 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GKMKNIOF_01519 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GKMKNIOF_01520 1.1e-110 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKMKNIOF_01521 7.18e-25 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKMKNIOF_01522 1.01e-38 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GKMKNIOF_01523 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GKMKNIOF_01524 7.26e-35 - - - S - - - Protein conserved in bacteria
GKMKNIOF_01525 1.09e-74 - - - - - - - -
GKMKNIOF_01526 6.77e-111 - - - - - - - -
GKMKNIOF_01527 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
GKMKNIOF_01528 1.84e-238 - - - S - - - DUF218 domain
GKMKNIOF_01529 9.07e-143 - - - - - - - -
GKMKNIOF_01530 1.32e-137 - - - - - - - -
GKMKNIOF_01531 3.75e-178 yicL - - EG - - - EamA-like transporter family
GKMKNIOF_01532 3.18e-209 - - - EG - - - EamA-like transporter family
GKMKNIOF_01533 4.48e-206 - - - EG - - - EamA-like transporter family
GKMKNIOF_01534 5.51e-47 - - - - - - - -
GKMKNIOF_01535 1.03e-07 - - - - - - - -
GKMKNIOF_01536 1.02e-200 - - - - - - - -
GKMKNIOF_01539 8.6e-108 - - - M - - - NlpC/P60 family
GKMKNIOF_01540 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GKMKNIOF_01541 6.69e-84 - - - L - - - RelB antitoxin
GKMKNIOF_01542 1.83e-91 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_01543 3.65e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKMKNIOF_01544 5.63e-171 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_01545 1.74e-248 - - - G - - - Transmembrane secretion effector
GKMKNIOF_01546 3.66e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKMKNIOF_01547 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKMKNIOF_01548 7.48e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKMKNIOF_01549 9.04e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
GKMKNIOF_01550 9.42e-261 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKMKNIOF_01551 4.13e-99 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GKMKNIOF_01552 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
GKMKNIOF_01553 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GKMKNIOF_01554 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GKMKNIOF_01555 7.7e-149 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GKMKNIOF_01556 2.85e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKMKNIOF_01557 2.73e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_01558 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_01559 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01560 4.73e-84 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_01564 1.79e-74 - - - L - - - Resolvase, N-terminal
GKMKNIOF_01565 4.18e-208 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_01566 7.62e-134 - - - G - - - Phosphoglycerate mutase family
GKMKNIOF_01567 5.46e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKMKNIOF_01568 2.74e-06 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_01569 2.33e-120 - - - S - - - VanZ like family
GKMKNIOF_01570 1.49e-130 ylbE - - GM - - - NAD(P)H-binding
GKMKNIOF_01571 3.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKMKNIOF_01573 4.31e-204 - - - L ko:K07497 - ko00000 hmm pf00665
GKMKNIOF_01574 2.15e-127 - - - L - - - Helix-turn-helix domain
GKMKNIOF_01575 0.0 - - - E - - - Amino acid permease
GKMKNIOF_01577 1.14e-99 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKMKNIOF_01578 1.96e-110 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
GKMKNIOF_01579 2.64e-46 - - - - - - - -
GKMKNIOF_01580 1.67e-136 icaA - - M - - - Glycosyl transferase family group 2
GKMKNIOF_01581 2.21e-34 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
GKMKNIOF_01582 6.91e-118 - - - T - - - Putative diguanylate phosphodiesterase
GKMKNIOF_01583 5.12e-199 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKMKNIOF_01584 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKMKNIOF_01585 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKMKNIOF_01586 8.39e-195 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GKMKNIOF_01587 2.52e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GKMKNIOF_01588 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKMKNIOF_01589 2.85e-153 - - - - - - - -
GKMKNIOF_01590 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
GKMKNIOF_01591 8.04e-190 - - - S - - - hydrolase
GKMKNIOF_01592 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKMKNIOF_01593 2.76e-221 ybbR - - S - - - YbbR-like protein
GKMKNIOF_01594 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKMKNIOF_01595 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_01596 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01597 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_01598 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKMKNIOF_01599 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GKMKNIOF_01600 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKMKNIOF_01601 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GKMKNIOF_01602 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GKMKNIOF_01603 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKMKNIOF_01604 2.81e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKMKNIOF_01605 3.07e-124 - - - - - - - -
GKMKNIOF_01606 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKMKNIOF_01607 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKMKNIOF_01608 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GKMKNIOF_01609 4.61e-149 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKMKNIOF_01610 4.47e-148 - - - L ko:K07497 - ko00000 hmm pf00665
GKMKNIOF_01611 7.7e-126 - - - L - - - Helix-turn-helix domain
GKMKNIOF_01612 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_01613 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKMKNIOF_01614 1.45e-133 - - - - - - - -
GKMKNIOF_01616 5.01e-55 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKMKNIOF_01617 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKMKNIOF_01618 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKMKNIOF_01619 2.69e-156 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
GKMKNIOF_01620 6.07e-138 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GKMKNIOF_01621 4.66e-179 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKMKNIOF_01622 8.63e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GKMKNIOF_01623 8.73e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKMKNIOF_01624 9.14e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKMKNIOF_01625 4.84e-42 - - - - - - - -
GKMKNIOF_01626 6.28e-256 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKMKNIOF_01627 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKMKNIOF_01628 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GKMKNIOF_01629 1.39e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GKMKNIOF_01630 6.75e-216 - - - K - - - LysR substrate binding domain
GKMKNIOF_01631 9.32e-109 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_01632 1.41e-51 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKMKNIOF_01633 3.01e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKMKNIOF_01634 1.03e-206 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GKMKNIOF_01635 1.38e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKMKNIOF_01636 8.7e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKMKNIOF_01637 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKMKNIOF_01638 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKMKNIOF_01639 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GKMKNIOF_01640 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GKMKNIOF_01641 3.75e-168 - - - K - - - rpiR family
GKMKNIOF_01642 7.66e-248 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKMKNIOF_01643 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKMKNIOF_01644 1.32e-151 - - - S - - - Putative esterase
GKMKNIOF_01645 3.39e-154 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKMKNIOF_01646 1.92e-102 - - - K - - - Helix-turn-helix domain, rpiR family
GKMKNIOF_01648 0.0 mdr - - EGP - - - Major Facilitator
GKMKNIOF_01649 7.29e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKMKNIOF_01652 5.31e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKMKNIOF_01655 9.91e-150 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GKMKNIOF_01656 9.67e-104 - - - - - - - -
GKMKNIOF_01657 6.74e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
GKMKNIOF_01658 1.68e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GKMKNIOF_01659 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKMKNIOF_01660 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
GKMKNIOF_01661 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKMKNIOF_01662 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GKMKNIOF_01663 5.5e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKMKNIOF_01664 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GKMKNIOF_01665 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GKMKNIOF_01666 9.62e-116 ypmB - - S - - - Protein conserved in bacteria
GKMKNIOF_01667 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GKMKNIOF_01668 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GKMKNIOF_01669 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKMKNIOF_01670 3.02e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GKMKNIOF_01671 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GKMKNIOF_01672 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GKMKNIOF_01673 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKMKNIOF_01674 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKMKNIOF_01675 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GKMKNIOF_01676 4.4e-215 - - - - - - - -
GKMKNIOF_01677 4.01e-184 - - - - - - - -
GKMKNIOF_01678 1.27e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKMKNIOF_01679 3.49e-36 - - - - - - - -
GKMKNIOF_01680 3.85e-193 - - - - - - - -
GKMKNIOF_01681 2.54e-176 - - - - - - - -
GKMKNIOF_01682 1.65e-180 - - - - - - - -
GKMKNIOF_01683 1.33e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKMKNIOF_01684 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
GKMKNIOF_01685 2.86e-307 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKMKNIOF_01686 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKMKNIOF_01687 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GKMKNIOF_01688 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GKMKNIOF_01689 4.34e-166 - - - S - - - Peptidase family M23
GKMKNIOF_01690 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
GKMKNIOF_01691 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GKMKNIOF_01692 7.71e-133 - - - L - - - Integrase
GKMKNIOF_01693 0.0 - - - L - - - Plasmid pRiA4b ORF-3-like protein
GKMKNIOF_01694 6.1e-186 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_01695 2.55e-65 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_01696 0.0 - - - I - - - Protein of unknown function (DUF2974)
GKMKNIOF_01697 4.2e-249 pbpX1 - - V - - - Beta-lactamase
GKMKNIOF_01698 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKMKNIOF_01699 9.03e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKMKNIOF_01700 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKMKNIOF_01701 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKMKNIOF_01702 3.29e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKMKNIOF_01703 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKMKNIOF_01704 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKMKNIOF_01705 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKMKNIOF_01706 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKMKNIOF_01707 1.27e-220 potE - - E - - - Amino Acid
GKMKNIOF_01708 2.58e-48 potE - - E - - - Amino Acid
GKMKNIOF_01709 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GKMKNIOF_01710 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKMKNIOF_01711 2.49e-282 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKMKNIOF_01712 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKMKNIOF_01713 2.21e-190 - - - - - - - -
GKMKNIOF_01714 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKMKNIOF_01715 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKMKNIOF_01716 3.64e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GKMKNIOF_01717 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GKMKNIOF_01718 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GKMKNIOF_01719 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GKMKNIOF_01720 1.42e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GKMKNIOF_01721 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKMKNIOF_01722 5.21e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GKMKNIOF_01723 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GKMKNIOF_01724 3.91e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKMKNIOF_01725 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GKMKNIOF_01726 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKMKNIOF_01727 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
GKMKNIOF_01728 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKMKNIOF_01729 2.34e-40 - - - L - - - Transposase and inactivated derivatives, IS30 family
GKMKNIOF_01730 9.14e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKMKNIOF_01731 8.11e-245 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKMKNIOF_01732 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GKMKNIOF_01733 4.22e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKMKNIOF_01734 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKMKNIOF_01735 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKMKNIOF_01736 6.72e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GKMKNIOF_01737 4.83e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKMKNIOF_01738 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKMKNIOF_01739 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GKMKNIOF_01740 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKMKNIOF_01741 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GKMKNIOF_01742 5.56e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
GKMKNIOF_01743 2.26e-215 degV1 - - S - - - DegV family
GKMKNIOF_01744 1.23e-170 - - - V - - - ABC transporter transmembrane region
GKMKNIOF_01745 4.76e-213 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GKMKNIOF_01746 3.81e-18 - - - S - - - CsbD-like
GKMKNIOF_01747 2.26e-31 - - - S - - - Transglycosylase associated protein
GKMKNIOF_01748 1.37e-287 - - - I - - - Protein of unknown function (DUF2974)
GKMKNIOF_01749 3.92e-153 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GKMKNIOF_01752 7.2e-84 - - - - - - - -
GKMKNIOF_01753 8.29e-67 - - - - - - - -
GKMKNIOF_01754 1.36e-171 - - - D - - - Ftsk spoiiie family protein
GKMKNIOF_01755 5.28e-180 - - - S - - - Replication initiation factor
GKMKNIOF_01756 1.33e-72 - - - - - - - -
GKMKNIOF_01757 4.04e-36 - - - - - - - -
GKMKNIOF_01758 3.5e-280 - - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_01760 9.75e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKMKNIOF_01761 8.25e-65 - - - V ko:K01990,ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
GKMKNIOF_01763 6.56e-86 sagB - - C - - - Nitroreductase family
GKMKNIOF_01765 4.04e-55 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
GKMKNIOF_01769 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKMKNIOF_01770 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GKMKNIOF_01771 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKMKNIOF_01772 2.14e-231 - - - M - - - CHAP domain
GKMKNIOF_01773 2.79e-102 - - - - - - - -
GKMKNIOF_01774 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKMKNIOF_01775 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKMKNIOF_01776 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKMKNIOF_01777 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKMKNIOF_01778 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKMKNIOF_01779 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKMKNIOF_01780 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKMKNIOF_01781 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKMKNIOF_01782 6.15e-268 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKMKNIOF_01783 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GKMKNIOF_01784 1.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKMKNIOF_01785 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKMKNIOF_01786 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
GKMKNIOF_01787 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKMKNIOF_01788 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
GKMKNIOF_01789 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKMKNIOF_01790 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKMKNIOF_01791 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKMKNIOF_01792 5.62e-95 yslB - - S - - - Protein of unknown function (DUF2507)
GKMKNIOF_01793 4.13e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKMKNIOF_01794 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKMKNIOF_01795 1.55e-29 - - - - - - - -
GKMKNIOF_01796 5.52e-58 - - - K - - - LytTr DNA-binding domain
GKMKNIOF_01798 1.71e-128 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKMKNIOF_01799 1.09e-148 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKMKNIOF_01800 3.26e-292 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_01801 4.65e-120 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_01802 8.87e-226 ydbI - - K - - - AI-2E family transporter
GKMKNIOF_01803 3.93e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKMKNIOF_01804 2.55e-26 - - - - - - - -
GKMKNIOF_01805 1.59e-315 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKMKNIOF_01806 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01807 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKMKNIOF_01808 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GKMKNIOF_01809 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKMKNIOF_01810 4.17e-201 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GKMKNIOF_01811 5.74e-206 yvgN - - C - - - Aldo keto reductase
GKMKNIOF_01812 0.0 fusA1 - - J - - - elongation factor G
GKMKNIOF_01813 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
GKMKNIOF_01814 1.07e-179 - - - EGP - - - Major Facilitator Superfamily
GKMKNIOF_01815 9.62e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKMKNIOF_01816 1.44e-07 - - - S - - - YSIRK type signal peptide
GKMKNIOF_01819 5.73e-201 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKMKNIOF_01820 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GKMKNIOF_01821 0.0 - - - L - - - Helicase C-terminal domain protein
GKMKNIOF_01822 1.36e-260 pbpX - - V - - - Beta-lactamase
GKMKNIOF_01823 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GKMKNIOF_01824 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKMKNIOF_01825 0.0 - - - L - - - Transposase DDE domain
GKMKNIOF_01826 5.73e-153 - - - - - - - -
GKMKNIOF_01827 6.59e-296 - - - L - - - Transposase DDE domain
GKMKNIOF_01828 2.09e-78 - - - S - - - Phage capsid family
GKMKNIOF_01830 2.6e-37 - - - - - - - -
GKMKNIOF_01831 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GKMKNIOF_01832 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKMKNIOF_01833 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKMKNIOF_01834 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKMKNIOF_01835 2.63e-205 coiA - - S ko:K06198 - ko00000 Competence protein
GKMKNIOF_01836 5.74e-148 yjbH - - Q - - - Thioredoxin
GKMKNIOF_01837 2.44e-143 - - - S - - - CYTH
GKMKNIOF_01838 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GKMKNIOF_01839 1.57e-194 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKMKNIOF_01840 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKMKNIOF_01841 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GKMKNIOF_01842 3.77e-122 - - - S - - - SNARE associated Golgi protein
GKMKNIOF_01843 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GKMKNIOF_01844 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
GKMKNIOF_01845 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
GKMKNIOF_01846 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKMKNIOF_01847 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
GKMKNIOF_01848 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKMKNIOF_01849 1.47e-284 ymfF - - S - - - Peptidase M16 inactive domain protein
GKMKNIOF_01850 5.49e-301 ymfH - - S - - - Peptidase M16
GKMKNIOF_01851 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GKMKNIOF_01852 1.63e-154 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
GKMKNIOF_01853 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKMKNIOF_01854 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKMKNIOF_01855 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GKMKNIOF_01856 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GKMKNIOF_01857 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GKMKNIOF_01858 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GKMKNIOF_01859 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GKMKNIOF_01860 8.08e-108 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_01861 1.32e-105 - - - S - - - PFAM Archaeal ATPase
GKMKNIOF_01862 7.02e-36 - - - - - - - -
GKMKNIOF_01863 2.22e-296 - - - E ko:K03294 - ko00000 amino acid
GKMKNIOF_01864 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GKMKNIOF_01865 1.91e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_01866 1.05e-67 - - - - - - - -
GKMKNIOF_01867 3.62e-202 - - - EGP - - - Major facilitator Superfamily
GKMKNIOF_01868 8.6e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GKMKNIOF_01869 3.43e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKMKNIOF_01870 5.14e-248 - - - S - - - DUF218 domain
GKMKNIOF_01871 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01872 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GKMKNIOF_01873 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
GKMKNIOF_01874 1.97e-255 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GKMKNIOF_01875 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GKMKNIOF_01876 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GKMKNIOF_01877 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKMKNIOF_01878 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKMKNIOF_01879 3.08e-205 - - - S - - - Aldo/keto reductase family
GKMKNIOF_01880 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKMKNIOF_01881 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GKMKNIOF_01882 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GKMKNIOF_01883 6.64e-94 - - - - - - - -
GKMKNIOF_01884 2.56e-179 - - - S - - - haloacid dehalogenase-like hydrolase
GKMKNIOF_01885 9.69e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKMKNIOF_01886 3.85e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKMKNIOF_01887 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKMKNIOF_01888 8.34e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01889 5.74e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKMKNIOF_01890 2.33e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GKMKNIOF_01891 7.2e-40 - - - - - - - -
GKMKNIOF_01892 5.49e-46 - - - - - - - -
GKMKNIOF_01893 8.69e-93 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKMKNIOF_01894 2.52e-76 - - - - - - - -
GKMKNIOF_01895 0.0 - - - S - - - ABC transporter
GKMKNIOF_01896 7.35e-174 - - - S - - - Putative threonine/serine exporter
GKMKNIOF_01897 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
GKMKNIOF_01898 1.58e-143 - - - S - - - Peptidase_C39 like family
GKMKNIOF_01899 1.16e-101 - - - - - - - -
GKMKNIOF_01900 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKMKNIOF_01901 4.75e-101 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GKMKNIOF_01902 5.48e-283 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_01903 8.77e-144 - - - - - - - -
GKMKNIOF_01904 0.0 - - - S - - - O-antigen ligase like membrane protein
GKMKNIOF_01905 4.52e-56 - - - - - - - -
GKMKNIOF_01906 4.26e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
GKMKNIOF_01907 1.47e-114 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GKMKNIOF_01908 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GKMKNIOF_01909 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GKMKNIOF_01910 3.01e-54 - - - - - - - -
GKMKNIOF_01911 1.26e-223 - - - S - - - Cysteine-rich secretory protein family
GKMKNIOF_01912 6.72e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKMKNIOF_01915 8.14e-241 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKMKNIOF_01916 5.52e-187 epsB - - M - - - biosynthesis protein
GKMKNIOF_01917 5.61e-160 ywqD - - D - - - Capsular exopolysaccharide family
GKMKNIOF_01918 2.22e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GKMKNIOF_01919 2.91e-140 epsE2 - - M - - - Bacterial sugar transferase
GKMKNIOF_01920 9.92e-152 cps3J - - M - - - Domain of unknown function (DUF4422)
GKMKNIOF_01922 8.06e-08 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
GKMKNIOF_01923 8.79e-222 - - - L - - - DDE superfamily endonuclease
GKMKNIOF_01924 2.63e-50 - - - - - - - -
GKMKNIOF_01925 1.25e-143 - - - K - - - WHG domain
GKMKNIOF_01926 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GKMKNIOF_01927 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GKMKNIOF_01928 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKMKNIOF_01929 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKMKNIOF_01931 2.99e-75 cvpA - - S - - - Colicin V production protein
GKMKNIOF_01932 2.24e-36 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_01933 2.12e-86 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_01934 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GKMKNIOF_01935 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKMKNIOF_01936 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GKMKNIOF_01937 4.28e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKMKNIOF_01938 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GKMKNIOF_01939 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKMKNIOF_01940 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
GKMKNIOF_01941 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01942 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01943 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKMKNIOF_01945 8.32e-157 vanR - - K - - - response regulator
GKMKNIOF_01946 9.28e-271 - - - T - - - His Kinase A (phosphoacceptor) domain
GKMKNIOF_01947 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKMKNIOF_01948 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GKMKNIOF_01949 6.94e-70 - - - S - - - Enterocin A Immunity
GKMKNIOF_01950 1.95e-45 - - - - - - - -
GKMKNIOF_01951 1.07e-35 - - - - - - - -
GKMKNIOF_01952 4.48e-34 - - - - - - - -
GKMKNIOF_01953 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
GKMKNIOF_01954 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GKMKNIOF_01955 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GKMKNIOF_01956 1.89e-23 - - - - - - - -
GKMKNIOF_01957 6.42e-73 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKMKNIOF_01958 1.86e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
GKMKNIOF_01959 6.09e-233 - - - S - - - Uncharacterised protein family (UPF0236)
GKMKNIOF_01960 6.79e-293 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_01961 0.0 - - - M - - - Peptidase family M1 domain
GKMKNIOF_01962 2.04e-226 - - - S - - - SLAP domain
GKMKNIOF_01963 4.65e-278 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GKMKNIOF_01964 2.59e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GKMKNIOF_01965 8.78e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKMKNIOF_01966 1.35e-71 ytpP - - CO - - - Thioredoxin
GKMKNIOF_01968 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKMKNIOF_01969 1.63e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKMKNIOF_01970 3.67e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_01971 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GKMKNIOF_01972 1.2e-41 - - - - - - - -
GKMKNIOF_01973 3.12e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKMKNIOF_01974 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
GKMKNIOF_01975 0.0 - - - - - - - -
GKMKNIOF_01976 9.67e-33 - - - S - - - Domain of unknown function DUF1829
GKMKNIOF_01978 4.53e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKMKNIOF_01979 0.0 yhaN - - L - - - AAA domain
GKMKNIOF_01980 1.27e-290 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GKMKNIOF_01981 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
GKMKNIOF_01982 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKMKNIOF_01983 1.21e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKMKNIOF_01984 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GKMKNIOF_01985 1.23e-242 - - - S - - - TerB-C domain
GKMKNIOF_01986 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
GKMKNIOF_01987 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GKMKNIOF_01988 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
GKMKNIOF_01989 9.05e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
GKMKNIOF_01990 3.36e-42 - - - - - - - -
GKMKNIOF_01991 1.78e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GKMKNIOF_01992 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GKMKNIOF_01993 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
GKMKNIOF_01994 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKMKNIOF_01995 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKMKNIOF_01996 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
GKMKNIOF_01997 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKMKNIOF_01998 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GKMKNIOF_01999 4.47e-58 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GKMKNIOF_02000 1.13e-308 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKMKNIOF_02001 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKMKNIOF_02002 2.07e-203 - - - K - - - Transcriptional regulator
GKMKNIOF_02003 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
GKMKNIOF_02004 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
GKMKNIOF_02005 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
GKMKNIOF_02006 2.72e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GKMKNIOF_02008 1.86e-114 ymdB - - S - - - Macro domain protein
GKMKNIOF_02010 2.57e-206 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_02011 1.21e-243 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GKMKNIOF_02012 1.75e-89 - - - S - - - Domain of unknown function (DUF1934)
GKMKNIOF_02013 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKMKNIOF_02014 1.03e-55 - - - - - - - -
GKMKNIOF_02015 1.37e-219 - - - GK - - - ROK family
GKMKNIOF_02016 5.4e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKMKNIOF_02017 0.0 - - - S - - - SLAP domain
GKMKNIOF_02018 5.52e-113 - - - - - - - -
GKMKNIOF_02019 1.81e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKMKNIOF_02020 2.05e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GKMKNIOF_02021 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
GKMKNIOF_02022 8.93e-194 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKMKNIOF_02023 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKMKNIOF_02024 2.72e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GKMKNIOF_02025 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKMKNIOF_02026 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKMKNIOF_02027 1.71e-173 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKMKNIOF_02028 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
GKMKNIOF_02029 1.5e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
GKMKNIOF_02030 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKMKNIOF_02031 7.04e-145 - - - E - - - Belongs to the SOS response-associated peptidase family
GKMKNIOF_02033 1.17e-143 - - - - - - - -
GKMKNIOF_02034 8.08e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKMKNIOF_02035 3.4e-93 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKMKNIOF_02036 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GKMKNIOF_02037 3.74e-125 - - - - - - - -
GKMKNIOF_02038 5.57e-22 - - - S - - - Protein of unknown function (DUF1275)
GKMKNIOF_02039 4.52e-114 - - - S - - - Protein of unknown function (DUF1275)
GKMKNIOF_02040 2.02e-46 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKMKNIOF_02041 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKMKNIOF_02042 1.89e-312 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKMKNIOF_02043 7.28e-97 - - - K - - - acetyltransferase
GKMKNIOF_02044 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKMKNIOF_02045 2.07e-196 msmR - - K - - - AraC-like ligand binding domain
GKMKNIOF_02046 7.15e-295 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GKMKNIOF_02047 9.63e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKMKNIOF_02048 1.1e-54 - - - K - - - Helix-turn-helix
GKMKNIOF_02049 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GKMKNIOF_02050 7.01e-207 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
GKMKNIOF_02051 3.06e-307 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
GKMKNIOF_02052 2.13e-53 - - - - - - - -
GKMKNIOF_02054 5.2e-119 - - - D - - - ftsk spoiiie
GKMKNIOF_02056 5.45e-72 - - - - - - - -
GKMKNIOF_02057 5.22e-18 - - - S - - - Domain of unknown function (DUF3173)
GKMKNIOF_02058 6.03e-215 - - - L - - - Belongs to the 'phage' integrase family
GKMKNIOF_02059 4e-79 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_02061 7.68e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GKMKNIOF_02062 3.84e-113 - - - S - - - COG NOG38524 non supervised orthologous group
GKMKNIOF_02063 2.09e-105 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKMKNIOF_02064 3.16e-179 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GKMKNIOF_02065 7.8e-10 - - - S - - - Protein of unknown function (DUF3290)
GKMKNIOF_02067 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GKMKNIOF_02068 1.71e-128 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GKMKNIOF_02069 2.02e-137 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKMKNIOF_02070 9.63e-204 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKMKNIOF_02071 1.12e-85 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKMKNIOF_02072 6.84e-243 - - - L ko:K07478 - ko00000 AAA C-terminal domain
GKMKNIOF_02073 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKMKNIOF_02074 5.74e-108 - - - K - - - Acetyltransferase (GNAT) domain
GKMKNIOF_02075 1.87e-290 - - - S - - - Putative peptidoglycan binding domain
GKMKNIOF_02076 3.21e-123 - - - S - - - ECF-type riboflavin transporter, S component
GKMKNIOF_02077 3.1e-127 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GKMKNIOF_02078 1.59e-259 pbpX1 - - V - - - Beta-lactamase
GKMKNIOF_02079 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKMKNIOF_02080 1.12e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKMKNIOF_02081 4.87e-262 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKMKNIOF_02082 5.94e-148 - - - I - - - Acid phosphatase homologues
GKMKNIOF_02083 2.25e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GKMKNIOF_02084 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GKMKNIOF_02085 3.6e-106 - - - C - - - Flavodoxin
GKMKNIOF_02086 7.52e-221 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKMKNIOF_02087 2.37e-169 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_02089 2.99e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKMKNIOF_02090 1.01e-98 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GKMKNIOF_02091 2.36e-123 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKMKNIOF_02092 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKMKNIOF_02093 8.33e-27 - - - - - - - -
GKMKNIOF_02094 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKMKNIOF_02095 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKMKNIOF_02096 3.31e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GKMKNIOF_02097 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKMKNIOF_02098 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKMKNIOF_02099 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKMKNIOF_02100 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKMKNIOF_02101 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
GKMKNIOF_02102 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GKMKNIOF_02103 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GKMKNIOF_02104 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GKMKNIOF_02105 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKMKNIOF_02106 0.0 - - - S - - - SH3-like domain
GKMKNIOF_02107 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_02108 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
GKMKNIOF_02109 1.22e-192 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
GKMKNIOF_02112 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKMKNIOF_02113 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKMKNIOF_02114 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKMKNIOF_02115 4.62e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKMKNIOF_02116 5.77e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GKMKNIOF_02117 4.41e-216 yitL - - S ko:K00243 - ko00000 S1 domain
GKMKNIOF_02118 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GKMKNIOF_02119 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKMKNIOF_02120 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKMKNIOF_02121 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
GKMKNIOF_02122 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKMKNIOF_02123 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GKMKNIOF_02124 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
GKMKNIOF_02125 1.18e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKMKNIOF_02126 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKMKNIOF_02127 0.0 oatA - - I - - - Acyltransferase
GKMKNIOF_02128 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKMKNIOF_02129 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKMKNIOF_02130 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
GKMKNIOF_02131 1.85e-141 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKMKNIOF_02132 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GKMKNIOF_02133 3.33e-178 blpT - - - - - - -
GKMKNIOF_02136 7.87e-30 - - - - - - - -
GKMKNIOF_02137 4.74e-107 - - - - - - - -
GKMKNIOF_02138 7.4e-41 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GKMKNIOF_02139 2.52e-32 - - - - - - - -
GKMKNIOF_02140 3.41e-88 - - - - - - - -
GKMKNIOF_02141 1.26e-211 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_02142 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKMKNIOF_02143 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
GKMKNIOF_02144 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKMKNIOF_02145 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
GKMKNIOF_02146 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GKMKNIOF_02147 9.9e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKMKNIOF_02148 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKMKNIOF_02149 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GKMKNIOF_02150 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKMKNIOF_02151 6.6e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKMKNIOF_02152 2.04e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GKMKNIOF_02153 0.000868 - - - - - - - -
GKMKNIOF_02154 1.13e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKMKNIOF_02156 2.77e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKMKNIOF_02157 3.71e-76 yodB - - K - - - Transcriptional regulator, HxlR family
GKMKNIOF_02159 1.48e-138 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
GKMKNIOF_02160 1.68e-149 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
GKMKNIOF_02161 4.57e-163 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_02162 3.72e-202 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GKMKNIOF_02163 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKMKNIOF_02164 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKMKNIOF_02165 7.84e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKMKNIOF_02166 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
GKMKNIOF_02167 2.24e-202 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKMKNIOF_02168 1.8e-34 - - - - - - - -
GKMKNIOF_02169 0.0 sufI - - Q - - - Multicopper oxidase
GKMKNIOF_02170 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKMKNIOF_02171 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKMKNIOF_02172 6.53e-291 - - - Q - - - Imidazolonepropionase and related amidohydrolases
GKMKNIOF_02173 2.48e-313 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
GKMKNIOF_02174 3.2e-176 - - - S - - - Protein of unknown function (DUF3100)
GKMKNIOF_02175 2.87e-107 - - - S - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_02176 6.73e-129 - - - L - - - An automated process has identified a potential problem with this gene model
GKMKNIOF_02177 3.31e-204 - - - S - - - EDD domain protein, DegV family
GKMKNIOF_02178 2.06e-88 - - - - - - - -
GKMKNIOF_02179 0.0 FbpA - - K - - - Fibronectin-binding protein
GKMKNIOF_02180 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKMKNIOF_02181 2.39e-254 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKMKNIOF_02182 2.28e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKMKNIOF_02183 1.1e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKMKNIOF_02184 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GKMKNIOF_02185 1.61e-70 - - - - - - - -
GKMKNIOF_02186 3.15e-132 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
GKMKNIOF_02187 5.56e-07 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKMKNIOF_02188 8.99e-100 - - - S ko:K07126 - ko00000 Sel1-like repeats.
GKMKNIOF_02189 5.77e-127 - - - S - - - AAA domain
GKMKNIOF_02190 3.02e-232 - - - - - - - -
GKMKNIOF_02191 8.53e-45 - - - - - - - -
GKMKNIOF_02192 6.75e-101 - - - S - - - HIRAN
GKMKNIOF_02193 1.3e-62 - - - L - - - DNA helicase
GKMKNIOF_02194 1.04e-144 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GKMKNIOF_02195 1.2e-220 - - - - - - - -
GKMKNIOF_02196 1.86e-31 - - - K - - - Acetyltransferase (GNAT) domain
GKMKNIOF_02198 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
GKMKNIOF_02199 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
GKMKNIOF_02200 1.89e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
GKMKNIOF_02201 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GKMKNIOF_02202 2.12e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_02203 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
GKMKNIOF_02204 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_02205 1.64e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
GKMKNIOF_02206 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKMKNIOF_02207 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKMKNIOF_02208 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GKMKNIOF_02209 1.29e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
GKMKNIOF_02210 5.11e-203 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKMKNIOF_02211 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
GKMKNIOF_02212 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
GKMKNIOF_02213 2.08e-95 yfhC - - C - - - nitroreductase
GKMKNIOF_02214 3.87e-16 - - - S - - - Domain of unknown function (DUF4767)
GKMKNIOF_02215 1.62e-105 yveB - - I - - - PAP2 superfamily
GKMKNIOF_02216 8.82e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKMKNIOF_02217 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GKMKNIOF_02218 1.63e-200 - - - I - - - alpha/beta hydrolase fold
GKMKNIOF_02219 7.8e-167 yibF - - S - - - overlaps another CDS with the same product name
GKMKNIOF_02220 1.69e-258 yibE - - S - - - overlaps another CDS with the same product name
GKMKNIOF_02221 8.18e-163 - - - - - - - -
GKMKNIOF_02222 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GKMKNIOF_02223 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
GKMKNIOF_02224 5.85e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_02225 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKMKNIOF_02226 1.11e-177 - - - - - - - -
GKMKNIOF_02227 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
GKMKNIOF_02228 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKMKNIOF_02229 3.49e-50 - - - - - - - -
GKMKNIOF_02230 2.18e-103 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKMKNIOF_02231 5.03e-297 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKMKNIOF_02232 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKMKNIOF_02233 2.55e-223 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
GKMKNIOF_02234 1.39e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
GKMKNIOF_02235 4.92e-73 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
GKMKNIOF_02236 1.22e-157 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKMKNIOF_02237 2.28e-21 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_02238 1.18e-89 - - - S - - - PD-(D/E)XK nuclease family transposase
GKMKNIOF_02239 4.07e-140 - - - K - - - LysR family
GKMKNIOF_02240 0.0 - - - C - - - FMN_bind
GKMKNIOF_02241 2.52e-140 - - - K - - - LysR family
GKMKNIOF_02242 3.53e-287 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKMKNIOF_02243 0.0 - - - C - - - FMN_bind
GKMKNIOF_02244 1.1e-128 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKMKNIOF_02245 6.18e-123 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GKMKNIOF_02246 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKMKNIOF_02247 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GKMKNIOF_02248 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKMKNIOF_02249 1.25e-192 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKMKNIOF_02250 3.01e-255 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKMKNIOF_02251 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GKMKNIOF_02252 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GKMKNIOF_02253 1.77e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKMKNIOF_02254 9.22e-141 yqeK - - H - - - Hydrolase, HD family
GKMKNIOF_02255 5.95e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKMKNIOF_02256 8.01e-276 ylbM - - S - - - Belongs to the UPF0348 family
GKMKNIOF_02257 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GKMKNIOF_02258 3.52e-163 csrR - - K - - - response regulator
GKMKNIOF_02259 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKMKNIOF_02260 2.19e-18 - - - - - - - -
GKMKNIOF_02261 4.28e-125 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKMKNIOF_02262 2.95e-283 - - - S - - - SLAP domain
GKMKNIOF_02263 3.23e-108 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GKMKNIOF_02264 2.43e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKMKNIOF_02265 1.32e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GKMKNIOF_02266 1.32e-120 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKMKNIOF_02267 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GKMKNIOF_02268 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GKMKNIOF_02269 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
GKMKNIOF_02270 1.14e-164 terC - - P - - - Integral membrane protein TerC family
GKMKNIOF_02271 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
GKMKNIOF_02272 4.04e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GKMKNIOF_02273 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKMKNIOF_02274 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKMKNIOF_02275 1.4e-191 yhaH - - S - - - Protein of unknown function (DUF805)
GKMKNIOF_02276 2.42e-204 - - - L - - - HNH nucleases
GKMKNIOF_02277 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GKMKNIOF_02278 3.67e-225 - - - G - - - Glycosyl hydrolases family 8
GKMKNIOF_02279 4.75e-239 - - - M - - - Glycosyl transferase
GKMKNIOF_02280 1.34e-09 - - - S - - - Uncharacterised protein family (UPF0236)
GKMKNIOF_02281 9.69e-25 - - - - - - - -
GKMKNIOF_02282 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GKMKNIOF_02283 3.34e-92 - - - S - - - Iron-sulphur cluster biosynthesis
GKMKNIOF_02284 7.23e-244 ysdE - - P - - - Citrate transporter
GKMKNIOF_02285 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
GKMKNIOF_02286 9.49e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GKMKNIOF_02287 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
GKMKNIOF_02289 4.47e-81 - - - L - - - Phage integrase family
GKMKNIOF_02290 1.93e-138 - - - L - - - Phage integrase family
GKMKNIOF_02291 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GKMKNIOF_02292 5.35e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKMKNIOF_02293 5.08e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKMKNIOF_02294 1.53e-175 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKMKNIOF_02295 1.58e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKMKNIOF_02296 5.91e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKMKNIOF_02297 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GKMKNIOF_02298 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKMKNIOF_02299 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKMKNIOF_02300 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKMKNIOF_02301 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GKMKNIOF_02302 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKMKNIOF_02303 1.51e-154 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKMKNIOF_02304 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKMKNIOF_02305 4.95e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKMKNIOF_02306 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GKMKNIOF_02307 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKMKNIOF_02308 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKMKNIOF_02309 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKMKNIOF_02310 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKMKNIOF_02311 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKMKNIOF_02312 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKMKNIOF_02313 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKMKNIOF_02314 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKMKNIOF_02315 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKMKNIOF_02316 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GKMKNIOF_02317 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKMKNIOF_02318 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKMKNIOF_02319 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKMKNIOF_02320 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKMKNIOF_02321 3.3e-197 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKMKNIOF_02322 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKMKNIOF_02323 5.43e-62 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)