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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KIOLHBIL_00001	1.38e-121	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIOLHBIL_00002	8.36e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KIOLHBIL_00003	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KIOLHBIL_00004	3.86e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KIOLHBIL_00005	6e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KIOLHBIL_00006	3.08e-57	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
KIOLHBIL_00007	7.76e-89	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
KIOLHBIL_00008	5.36e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KIOLHBIL_00009	3.96e-177	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KIOLHBIL_00010	7.76e-183	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOLHBIL_00011	8.19e-190	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOLHBIL_00012	3.23e-270	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KIOLHBIL_00013	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
KIOLHBIL_00014	1.11e-95	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
KIOLHBIL_00015	2.64e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KIOLHBIL_00016	1.24e-144	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIOLHBIL_00017	5.84e-13	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
KIOLHBIL_00019	1.55e-283	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KIOLHBIL_00020	2.3e-254	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOLHBIL_00021	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
KIOLHBIL_00022	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KIOLHBIL_00023	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIOLHBIL_00024	3.86e-299	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
KIOLHBIL_00025	3.22e-33	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	cytokinin biosynthetic process
KIOLHBIL_00026	5.17e-56	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	cytokinin biosynthetic process
KIOLHBIL_00027	9.81e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIOLHBIL_00028	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIOLHBIL_00029	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
KIOLHBIL_00030	6.68e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
KIOLHBIL_00031	7.6e-269	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KIOLHBIL_00032	3.06e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KIOLHBIL_00033	1.29e-280	brpA	-	-	K	-	-	-	Transcriptional
KIOLHBIL_00034	6.67e-120	-	-	-	M	-	-	-	Acetyltransferase GNAT Family
KIOLHBIL_00035	1.54e-101	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
KIOLHBIL_00036	1.32e-315	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KIOLHBIL_00037	1.46e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
KIOLHBIL_00038	5.27e-181	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
KIOLHBIL_00039	1.62e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00040	1.45e-161	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
KIOLHBIL_00041	2.02e-215	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
KIOLHBIL_00042	1.85e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
KIOLHBIL_00043	1.04e-306	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIOLHBIL_00044	5.17e-61	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_00045	1.74e-30	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00046	7.14e-67	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00047	1.08e-18	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00048	6.18e-34	yrdC	-	-	Q	-	-	-	isochorismatase
KIOLHBIL_00049	8.47e-20	yrdC	-	-	Q	-	-	-	isochorismatase
KIOLHBIL_00050	3.53e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KIOLHBIL_00051	6.23e-213	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KIOLHBIL_00052	4.48e-277	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
KIOLHBIL_00053	1.46e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIOLHBIL_00054	0.0	covS	-	-	T	-	-	-	Histidine kinase
KIOLHBIL_00055	2.69e-158	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOLHBIL_00056	2.8e-119	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
KIOLHBIL_00057	1.5e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
KIOLHBIL_00058	2.75e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
KIOLHBIL_00059	2.81e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
KIOLHBIL_00060	6.53e-12	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ascorbate 6-phosphate lactonase
KIOLHBIL_00061	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIOLHBIL_00062	1.18e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KIOLHBIL_00063	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_00064	5.41e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KIOLHBIL_00065	5.29e-138	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
KIOLHBIL_00066	2.03e-41	salL	2.5.1.63, 2.5.1.94	-	F	ko:K09134,ko:K21153,ko:K22205	-	ko00000,ko01000	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KIOLHBIL_00067	5.12e-268	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KIOLHBIL_00068	1.77e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_00069	7.56e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIOLHBIL_00070	6.17e-27	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
KIOLHBIL_00071	1.32e-38	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KIOLHBIL_00072	1.3e-88	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KIOLHBIL_00073	5.2e-113	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KIOLHBIL_00074	1.26e-212	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
KIOLHBIL_00075	5.16e-187	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
KIOLHBIL_00076	1.51e-45	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_00077	2.13e-179	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_00078	4.9e-266	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KIOLHBIL_00079	0.0	-	-	-	F	-	-	-	NUDIX domain
KIOLHBIL_00080	0.0	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOLHBIL_00081	1.88e-189	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
KIOLHBIL_00082	4.48e-170	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOLHBIL_00083	8.28e-177	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
KIOLHBIL_00084	7.11e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
KIOLHBIL_00085	1.78e-206	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIOLHBIL_00086	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KIOLHBIL_00087	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIOLHBIL_00088	2.74e-101	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
KIOLHBIL_00089	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KIOLHBIL_00090	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
KIOLHBIL_00091	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
KIOLHBIL_00092	2.16e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
KIOLHBIL_00093	3.38e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
KIOLHBIL_00094	6.43e-62	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOLHBIL_00095	4.51e-72	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
KIOLHBIL_00096	1.32e-16	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOLHBIL_00097	1.12e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOLHBIL_00098	3.36e-46	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
KIOLHBIL_00099	5.08e-207	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOLHBIL_00100	2.59e-145	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
KIOLHBIL_00101	5.63e-117	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KIOLHBIL_00102	1.34e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KIOLHBIL_00103	6.63e-313	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
KIOLHBIL_00104	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
KIOLHBIL_00105	1.23e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KIOLHBIL_00106	1.82e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOLHBIL_00107	7.56e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIOLHBIL_00108	8.23e-157	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIOLHBIL_00109	4.14e-175	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KIOLHBIL_00110	1.49e-112	ykuL	-	-	S	-	-	-	CBS domain
KIOLHBIL_00111	7.82e-128	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KIOLHBIL_00112	9.47e-236	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIOLHBIL_00113	9.38e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KIOLHBIL_00114	5.74e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
KIOLHBIL_00115	1.96e-115	-	-	-	K	-	-	-	transcriptional regulator
KIOLHBIL_00116	1.42e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KIOLHBIL_00119	4.03e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KIOLHBIL_00120	8.25e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
KIOLHBIL_00121	6.83e-169	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOLHBIL_00122	3.88e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KIOLHBIL_00123	3.44e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOLHBIL_00124	6.06e-36	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00125	1.51e-05	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00126	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIOLHBIL_00127	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIOLHBIL_00128	9.07e-107	XK27_09675	-	-	K	ko:K07105	-	ko00000	-acetyltransferase
KIOLHBIL_00129	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KIOLHBIL_00130	1.44e-26	XK27_11680	-	-	-	-	-	-	-
KIOLHBIL_00131	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
KIOLHBIL_00132	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KIOLHBIL_00133	2.06e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KIOLHBIL_00134	3.39e-67	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KIOLHBIL_00135	5.96e-122	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KIOLHBIL_00136	3.47e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KIOLHBIL_00137	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOLHBIL_00138	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KIOLHBIL_00139	5.58e-99	yhaI	-	-	L	-	-	-	Membrane
KIOLHBIL_00140	6.15e-195	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KIOLHBIL_00141	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIOLHBIL_00142	3.81e-40	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KIOLHBIL_00143	4e-225	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KIOLHBIL_00144	2.01e-52	napB	-	-	K	-	-	-	transcriptional
KIOLHBIL_00145	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOLHBIL_00146	2.05e-118	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
KIOLHBIL_00147	3.82e-47	cof	-	-	Q	-	-	-	phosphatase activity
KIOLHBIL_00148	4.76e-73	cof	-	-	Q	-	-	-	phosphatase activity
KIOLHBIL_00149	4.1e-111	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
KIOLHBIL_00150	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KIOLHBIL_00151	4.42e-35	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
KIOLHBIL_00152	4.01e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KIOLHBIL_00153	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOLHBIL_00154	1.94e-211	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KIOLHBIL_00155	5.21e-71	WQ51_06355	-	-	S	-	-	-	TM2 domain
KIOLHBIL_00157	2.67e-46	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00158	3.03e-40	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00159	1.82e-100	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_00160	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIOLHBIL_00161	4.47e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIOLHBIL_00162	8.63e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00163	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
KIOLHBIL_00164	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KIOLHBIL_00165	6.34e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KIOLHBIL_00166	1.29e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KIOLHBIL_00167	1.02e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIOLHBIL_00168	9.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
KIOLHBIL_00169	1.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
KIOLHBIL_00170	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KIOLHBIL_00171	5.74e-189	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
KIOLHBIL_00172	4.2e-255	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00173	3.44e-41	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00174	7.4e-29	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00175	5.91e-37	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00176	9.78e-40	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00177	4.85e-207	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
KIOLHBIL_00178	9.15e-168	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_00179	1.4e-172	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOLHBIL_00180	1.18e-90	adcR	-	-	K	-	-	-	transcriptional
KIOLHBIL_00181	7.55e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOLHBIL_00182	2.41e-234	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIOLHBIL_00183	9.47e-202	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIOLHBIL_00184	3.41e-15	-	-	-	-	-	-	-	-
KIOLHBIL_00185	4.42e-07	-	-	-	-	-	-	-	-
KIOLHBIL_00186	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KIOLHBIL_00187	2.78e-98	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KIOLHBIL_00188	1.7e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIOLHBIL_00189	1.98e-297	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
KIOLHBIL_00190	1.82e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KIOLHBIL_00191	7.24e-248	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KIOLHBIL_00192	2.76e-169	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KIOLHBIL_00193	5e-196	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KIOLHBIL_00194	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOLHBIL_00195	3e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_00196	1.42e-09	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOLHBIL_00197	6.96e-125	-	-	-	V	-	-	-	VanZ like family
KIOLHBIL_00198	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIOLHBIL_00199	3.52e-256	XK27_00055	-	-	P	-	-	-	Major Facilitator
KIOLHBIL_00200	7.75e-145	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KIOLHBIL_00201	4.2e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIOLHBIL_00202	9.52e-303	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIOLHBIL_00203	3.85e-67	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOLHBIL_00204	4.25e-70	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOLHBIL_00205	1.93e-33	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOLHBIL_00206	3.09e-13	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOLHBIL_00207	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KIOLHBIL_00208	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KIOLHBIL_00209	8.28e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KIOLHBIL_00210	2.27e-232	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_00211	8.18e-176	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_00212	6.81e-76	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
KIOLHBIL_00213	2.13e-173	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KIOLHBIL_00214	5.2e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KIOLHBIL_00215	2.55e-105	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KIOLHBIL_00216	1.45e-108	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
KIOLHBIL_00217	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KIOLHBIL_00218	1.02e-116	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KIOLHBIL_00219	6.47e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KIOLHBIL_00220	1.38e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KIOLHBIL_00221	8.45e-101	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
KIOLHBIL_00222	6.77e-111	-	-	-	-	-	-	-	-
KIOLHBIL_00223	3.02e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KIOLHBIL_00224	1e-74	amd	-	-	E	-	-	-	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOLHBIL_00225	5.1e-206	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00226	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
KIOLHBIL_00228	8.08e-105	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_00229	5.2e-114	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
KIOLHBIL_00230	8.27e-67	-	-	-	L	-	-	-	Transposase IS116 IS110 IS902
KIOLHBIL_00231	1.36e-303	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_00232	3.53e-41	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
KIOLHBIL_00234	2.85e-175	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KIOLHBIL_00235	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
KIOLHBIL_00236	3.51e-153	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Prolyl oligopeptidase family
KIOLHBIL_00237	3.76e-107	-	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KIOLHBIL_00238	9.69e-67	-	-	-	-	-	-	-	-
KIOLHBIL_00239	1.6e-193	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_00240	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIOLHBIL_00241	5.51e-101	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
KIOLHBIL_00242	2.18e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIOLHBIL_00243	9.96e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KIOLHBIL_00244	1.16e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIOLHBIL_00245	1.16e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIOLHBIL_00246	6.32e-136	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIOLHBIL_00247	2.07e-281	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
KIOLHBIL_00248	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
KIOLHBIL_00249	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KIOLHBIL_00250	5.69e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KIOLHBIL_00251	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIOLHBIL_00252	1.08e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
KIOLHBIL_00253	9.95e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
KIOLHBIL_00254	1.34e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
KIOLHBIL_00255	6.52e-33	XK27_07735	-	-	S	-	-	-	YjbR
KIOLHBIL_00256	2.13e-181	XK27_07735	-	-	S	-	-	-	YjbR
KIOLHBIL_00257	2.43e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KIOLHBIL_00258	1.03e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KIOLHBIL_00259	1.75e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIOLHBIL_00260	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
KIOLHBIL_00261	2.51e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
KIOLHBIL_00262	6.61e-157	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KIOLHBIL_00263	4.21e-208	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIOLHBIL_00264	5.89e-257	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIOLHBIL_00265	5.25e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIOLHBIL_00266	7.84e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KIOLHBIL_00267	1.48e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
KIOLHBIL_00268	1.88e-222	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KIOLHBIL_00269	1.77e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KIOLHBIL_00270	2.28e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIOLHBIL_00271	3.29e-195	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
KIOLHBIL_00272	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
KIOLHBIL_00273	4.35e-174	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
KIOLHBIL_00274	1.28e-255	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
KIOLHBIL_00275	7.4e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
KIOLHBIL_00276	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOLHBIL_00277	7.83e-131	-	-	-	-	-	-	-	-
KIOLHBIL_00279	2.55e-33	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KIOLHBIL_00280	3.77e-123	-	-	-	-	-	-	-	-
KIOLHBIL_00281	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KIOLHBIL_00282	6.55e-221	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_00283	8.44e-71	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_00284	1.54e-230	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
KIOLHBIL_00285	2.3e-189	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
KIOLHBIL_00286	2.68e-198	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
KIOLHBIL_00288	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
KIOLHBIL_00289	3.63e-113	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KIOLHBIL_00290	5.93e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
KIOLHBIL_00291	1.66e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KIOLHBIL_00292	1.51e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIOLHBIL_00293	1.14e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KIOLHBIL_00294	1.66e-91	ytxH	-	-	S	-	-	-	General stress protein
KIOLHBIL_00296	1.23e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
KIOLHBIL_00297	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
KIOLHBIL_00298	8.55e-59	-	-	-	S	-	-	-	CHY zinc finger
KIOLHBIL_00299	2.67e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
KIOLHBIL_00301	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
KIOLHBIL_00302	1.1e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOLHBIL_00304	3.17e-87	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KIOLHBIL_00305	0.0	-	-	-	L	-	-	-	helicase
KIOLHBIL_00306	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KIOLHBIL_00307	2.3e-213	-	-	-	M	-	-	-	LysM domain
KIOLHBIL_00308	2.16e-29	-	-	-	-	-	-	-	-
KIOLHBIL_00309	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
KIOLHBIL_00310	3.06e-151	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
KIOLHBIL_00311	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIOLHBIL_00312	3.61e-199	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
KIOLHBIL_00313	2.29e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
KIOLHBIL_00314	9.86e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIOLHBIL_00315	9.97e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
KIOLHBIL_00316	1.44e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
KIOLHBIL_00317	4.63e-20	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOLHBIL_00318	1.06e-69	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOLHBIL_00319	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOLHBIL_00321	8.62e-132	-	-	-	-	-	-	-	-
KIOLHBIL_00322	8.87e-291	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KIOLHBIL_00323	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
KIOLHBIL_00324	3.93e-189	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_00325	1.71e-185	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOLHBIL_00326	2.5e-53	-	-	-	I	-	-	-	radical SAM domain protein
KIOLHBIL_00327	2.67e-217	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOLHBIL_00328	2.68e-146	tra981A	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
KIOLHBIL_00329	2.17e-41	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_00330	0.0	-	-	-	M	-	-	-	family 8
KIOLHBIL_00331	3.71e-12	-	-	-	-	-	-	-	-
KIOLHBIL_00332	3.62e-44	-	-	-	K	ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
KIOLHBIL_00333	1.24e-26	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
KIOLHBIL_00334	1.51e-78	wbpB	1.1.1.335	-	S	ko:K13016	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	inositol 2-dehydrogenase activity
KIOLHBIL_00335	3.62e-43	-	-	-	Q	-	-	-	AMP-binding enzyme C-terminal domain
KIOLHBIL_00336	1.01e-145	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KIOLHBIL_00337	9.46e-62	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOLHBIL_00338	3.09e-110	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KIOLHBIL_00339	9.09e-85	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOLHBIL_00340	4.88e-140	-	-	-	E	-	-	-	LysE type translocator
KIOLHBIL_00341	2.1e-09	-	-	-	IQ	-	-	-	PFAM AMP-dependent synthetase and ligase
KIOLHBIL_00343	3.53e-92	-	-	-	-	-	-	-	-
KIOLHBIL_00345	5.37e-83	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
KIOLHBIL_00346	1.2e-68	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KIOLHBIL_00347	1.58e-50	BP1961	-	-	P	-	-	-	nitric oxide dioxygenase activity
KIOLHBIL_00349	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
KIOLHBIL_00350	2.71e-160	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
KIOLHBIL_00351	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
KIOLHBIL_00352	4.07e-130	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOLHBIL_00353	2.73e-204	yvgN	-	-	C	-	-	-	reductase
KIOLHBIL_00354	3.12e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KIOLHBIL_00355	5.79e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KIOLHBIL_00356	4.95e-144	ydgI	-	-	C	-	-	-	Nitroreductase
KIOLHBIL_00357	3.4e-294	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOLHBIL_00358	2.15e-202	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOLHBIL_00359	2.96e-100	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
KIOLHBIL_00360	4.16e-180	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
KIOLHBIL_00361	7e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
KIOLHBIL_00362	1.28e-09	ydhF	-	-	S	-	-	-	Aldo keto reductase
KIOLHBIL_00363	2.91e-34	ydhF	-	-	S	-	-	-	Aldo keto reductase
KIOLHBIL_00364	2.93e-75	ydhF	-	-	S	-	-	-	Aldo keto reductase
KIOLHBIL_00365	3.73e-109	-	-	-	K	-	-	-	WHG domain
KIOLHBIL_00366	3.07e-99	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00367	7.27e-29	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KIOLHBIL_00368	3.84e-54	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KIOLHBIL_00369	7.66e-106	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
KIOLHBIL_00370	1.63e-215	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
KIOLHBIL_00371	1.25e-206	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KIOLHBIL_00372	6.18e-144	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_00373	2.02e-148	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
KIOLHBIL_00374	1.81e-173	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_00377	3.59e-28	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00378	1.32e-176	-	-	-	S	-	-	-	dextransucrase activity
KIOLHBIL_00379	8.37e-106	-	-	-	S	-	-	-	dextransucrase activity
KIOLHBIL_00380	9.5e-184	-	-	-	S	-	-	-	dextransucrase activity
KIOLHBIL_00381	9.29e-294	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
KIOLHBIL_00382	2.67e-09	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
KIOLHBIL_00383	3.31e-35	csbD	-	-	K	-	-	-	CsbD-like
KIOLHBIL_00384	1.6e-75	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOLHBIL_00385	1.93e-56	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOLHBIL_00386	2.83e-299	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KIOLHBIL_00387	3.98e-231	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOLHBIL_00389	2.64e-97	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
KIOLHBIL_00390	1.68e-57	ykrV3	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
KIOLHBIL_00391	1.8e-55	ykrV3	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
KIOLHBIL_00392	2.28e-140	-	-	-	S	-	-	-	MmgE/PrpD family
KIOLHBIL_00393	3.76e-73	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KIOLHBIL_00394	8.13e-93	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_00395	2.66e-118	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_00396	3.83e-250	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase
KIOLHBIL_00397	1.27e-116	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOLHBIL_00398	6.71e-240	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOLHBIL_00399	2.78e-316	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
KIOLHBIL_00400	4.16e-251	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
KIOLHBIL_00401	5.49e-08	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
KIOLHBIL_00402	1.66e-98	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KIOLHBIL_00403	7.44e-159	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOLHBIL_00404	1.1e-211	-	-	-	T	-	-	-	Histidine kinase
KIOLHBIL_00405	6.05e-171	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOLHBIL_00406	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
KIOLHBIL_00407	6.55e-120	-	-	-	S	ko:K06940	-	ko00000	Fe-S-cluster oxidoreductase
KIOLHBIL_00410	7.02e-34	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOLHBIL_00411	1.4e-92	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
KIOLHBIL_00412	3.32e-50	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
KIOLHBIL_00414	1.03e-64	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KIOLHBIL_00415	3.01e-195	mutR	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOLHBIL_00417	1.41e-210	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
KIOLHBIL_00418	5.55e-144	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOLHBIL_00419	8.11e-41	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOLHBIL_00422	3.22e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
KIOLHBIL_00423	1.6e-114	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
KIOLHBIL_00424	2.66e-29	treR	-	-	K	ko:K03486,ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
KIOLHBIL_00425	2.11e-73	treB	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS System
KIOLHBIL_00426	1.94e-14	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOLHBIL_00427	4.14e-87	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOLHBIL_00428	4.39e-90	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOLHBIL_00429	9.08e-50	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOLHBIL_00430	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KIOLHBIL_00431	4.38e-16	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOLHBIL_00432	9.39e-31	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOLHBIL_00433	5.31e-163	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOLHBIL_00434	4.53e-85	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOLHBIL_00435	3.04e-48	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
KIOLHBIL_00436	1.27e-77	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOLHBIL_00437	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KIOLHBIL_00438	2.64e-286	norN	-	-	V	-	-	-	Mate efflux family protein
KIOLHBIL_00439	7.64e-76	asp	-	-	S	-	-	-	cog cog1302
KIOLHBIL_00440	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
KIOLHBIL_00441	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
KIOLHBIL_00442	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KIOLHBIL_00443	2.89e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KIOLHBIL_00444	2.67e-250	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KIOLHBIL_00445	1.01e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIOLHBIL_00446	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOLHBIL_00447	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOLHBIL_00448	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOLHBIL_00449	3.93e-91	-	-	-	S	-	-	-	cog cog4699
KIOLHBIL_00450	3.13e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KIOLHBIL_00451	1.22e-185	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KIOLHBIL_00452	6.4e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
KIOLHBIL_00453	2.43e-74	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
KIOLHBIL_00454	2.11e-20	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
KIOLHBIL_00455	3.1e-91	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
KIOLHBIL_00456	5.13e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
KIOLHBIL_00457	4.81e-226	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
KIOLHBIL_00458	3.27e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOLHBIL_00459	4.3e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
KIOLHBIL_00460	1.89e-34	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOLHBIL_00461	4.37e-30	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOLHBIL_00463	1.31e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
KIOLHBIL_00464	1.17e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIOLHBIL_00465	6.4e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
KIOLHBIL_00467	3.48e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
KIOLHBIL_00468	5.51e-147	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOLHBIL_00469	7.3e-245	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
KIOLHBIL_00470	2.25e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
KIOLHBIL_00471	6.32e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOLHBIL_00472	5.94e-118	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KIOLHBIL_00474	6.97e-203	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
KIOLHBIL_00475	2.67e-26	-	-	-	S	ko:K07025	-	ko00000	phosphatase activity
KIOLHBIL_00476	3.68e-45	-	-	-	S	ko:K07025	-	ko00000	phosphatase activity
KIOLHBIL_00477	1.22e-59	-	-	-	S	ko:K07025	-	ko00000	glycolate biosynthetic process
KIOLHBIL_00478	6.92e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KIOLHBIL_00479	2.22e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KIOLHBIL_00480	4.01e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KIOLHBIL_00481	1.62e-152	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
KIOLHBIL_00482	1.95e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KIOLHBIL_00483	6.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KIOLHBIL_00484	5.22e-109	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
KIOLHBIL_00485	2.8e-118	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
KIOLHBIL_00486	1.77e-178	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
KIOLHBIL_00487	4.64e-77	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
KIOLHBIL_00488	8.13e-98	-	-	-	S	-	-	-	reductase
KIOLHBIL_00489	3.06e-27	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
KIOLHBIL_00490	2.98e-104	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KIOLHBIL_00491	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIOLHBIL_00492	1.64e-16	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
KIOLHBIL_00493	1.92e-46	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
KIOLHBIL_00494	9.62e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
KIOLHBIL_00495	3.28e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KIOLHBIL_00496	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIOLHBIL_00497	2.36e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KIOLHBIL_00498	1.82e-97	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
KIOLHBIL_00499	1.28e-107	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
KIOLHBIL_00500	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIOLHBIL_00501	3.19e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KIOLHBIL_00502	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
KIOLHBIL_00503	7.08e-74	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KIOLHBIL_00504	1.8e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOLHBIL_00505	1.63e-235	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
KIOLHBIL_00506	4.24e-22	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
KIOLHBIL_00507	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
KIOLHBIL_00508	1.54e-42	-	-	-	L	ko:K07491	-	ko00000	Transposase
KIOLHBIL_00509	6.69e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KIOLHBIL_00514	1.65e-180	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KIOLHBIL_00515	1.1e-114	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KIOLHBIL_00516	5.1e-175	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
KIOLHBIL_00517	2.75e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOLHBIL_00518	2.17e-35	-	-	-	-	-	-	-	-
KIOLHBIL_00519	1.29e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOLHBIL_00520	5.9e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KIOLHBIL_00521	2.69e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KIOLHBIL_00522	1.93e-46	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOLHBIL_00523	1.5e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KIOLHBIL_00524	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOLHBIL_00525	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIOLHBIL_00526	4.91e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KIOLHBIL_00527	4.63e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIOLHBIL_00528	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KIOLHBIL_00529	6.6e-108	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_00530	1.37e-43	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00531	2.85e-41	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00532	4.38e-207	-	-	-	S	-	-	-	CHAP domain
KIOLHBIL_00533	4.06e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KIOLHBIL_00534	1.9e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIOLHBIL_00535	3.43e-260	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIOLHBIL_00536	2.92e-182	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
KIOLHBIL_00537	3.51e-43	-	-	-	-	-	-	-	-
KIOLHBIL_00538	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIOLHBIL_00539	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIOLHBIL_00540	1.24e-261	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOLHBIL_00541	4.58e-288	eno	4.2.1.11	-	F	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIOLHBIL_00542	3.21e-78	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KIOLHBIL_00543	3.61e-23	-	-	-	-	-	-	-	-
KIOLHBIL_00544	2.44e-151	-	4.1.1.22	-	H	ko:K01590	ko00340,ko01100,ko01110,map00340,map01100,map01110	ko00000,ko00001,ko01000	Histidine carboxylase PI chain
KIOLHBIL_00545	2.13e-216	arcD	-	-	E	ko:K03756,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
KIOLHBIL_00547	5.83e-30	-	-	-	L	ko:K04763	-	ko00000,ko03036	DNA integration
KIOLHBIL_00548	2.69e-105	-	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOLHBIL_00549	2.91e-199	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
KIOLHBIL_00550	7.7e-104	-	-	-	L	-	-	-	Resolvase, N terminal domain
KIOLHBIL_00551	2.45e-71	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KIOLHBIL_00552	2.47e-124	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
KIOLHBIL_00553	5.22e-78	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOLHBIL_00555	1.29e-103	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOLHBIL_00558	2.34e-291	-	-	-	KLT	-	-	-	serine threonine protein kinase
KIOLHBIL_00559	1.95e-103	-	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KIOLHBIL_00560	5.37e-73	-	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KIOLHBIL_00561	1.37e-129	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
KIOLHBIL_00563	5.48e-92	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	LysR substrate binding domain
KIOLHBIL_00564	1.91e-12	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOLHBIL_00565	5.18e-103	-	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOLHBIL_00566	4.38e-211	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
KIOLHBIL_00567	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
KIOLHBIL_00568	1.21e-244	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
KIOLHBIL_00569	1.47e-54	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
KIOLHBIL_00570	4.17e-22	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
KIOLHBIL_00572	1.36e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KIOLHBIL_00573	3.67e-73	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
KIOLHBIL_00574	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIOLHBIL_00575	5.1e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KIOLHBIL_00576	1.25e-80	-	-	-	KT	-	-	-	phosphorelay signal transduction system
KIOLHBIL_00577	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIOLHBIL_00579	4.38e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KIOLHBIL_00580	2.51e-88	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
KIOLHBIL_00581	6.87e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KIOLHBIL_00582	7.2e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIOLHBIL_00583	1.27e-86	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
KIOLHBIL_00584	1.92e-17	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOLHBIL_00585	4.29e-44	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOLHBIL_00586	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
KIOLHBIL_00587	4.49e-186	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
KIOLHBIL_00588	5.39e-111	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOLHBIL_00589	1.76e-60	hsdS_1	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
KIOLHBIL_00590	9.08e-43	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOLHBIL_00591	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
KIOLHBIL_00592	8.05e-149	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00593	1.89e-41	-	-	-	-	-	-	-	-
KIOLHBIL_00594	1.68e-234	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
KIOLHBIL_00595	6.35e-177	cppA	-	-	E	-	-	-	CppA N-terminal
KIOLHBIL_00596	1.9e-56	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOLHBIL_00597	7.59e-212	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOLHBIL_00598	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KIOLHBIL_00600	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00601	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00603	3.29e-121	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
KIOLHBIL_00604	1.36e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KIOLHBIL_00605	6.67e-137	yutD	-	-	J	-	-	-	protein conserved in bacteria
KIOLHBIL_00606	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_00608	2.16e-301	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIOLHBIL_00609	8.08e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIOLHBIL_00610	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KIOLHBIL_00611	3.74e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
KIOLHBIL_00612	2.67e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KIOLHBIL_00613	2.13e-143	-	-	-	-	-	-	-	-
KIOLHBIL_00614	8.81e-43	-	-	-	-	-	-	-	-
KIOLHBIL_00616	1.58e-42	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
KIOLHBIL_00617	2.37e-29	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOLHBIL_00618	6.75e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIOLHBIL_00619	2.89e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIOLHBIL_00620	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KIOLHBIL_00621	5.01e-170	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00622	3.09e-127	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOLHBIL_00623	6.65e-15	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOLHBIL_00624	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KIOLHBIL_00625	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KIOLHBIL_00626	2.11e-84	-	-	-	S	-	-	-	membrane
KIOLHBIL_00627	3.17e-84	-	-	-	KT	-	-	-	response to antibiotic
KIOLHBIL_00628	7.92e-21	-	-	-	KT	-	-	-	response to antibiotic
KIOLHBIL_00629	6.18e-117	yebC	-	-	M	-	-	-	Membrane
KIOLHBIL_00630	1.06e-20	yebC	-	-	M	-	-	-	Membrane
KIOLHBIL_00631	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
KIOLHBIL_00632	8.08e-223	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KIOLHBIL_00633	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIOLHBIL_00634	2e-245	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIOLHBIL_00635	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KIOLHBIL_00636	1.01e-251	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIOLHBIL_00637	8.28e-251	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIOLHBIL_00638	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KIOLHBIL_00640	1.78e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOLHBIL_00641	2.37e-220	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
KIOLHBIL_00642	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_00643	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KIOLHBIL_00644	3.96e-149	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional
KIOLHBIL_00645	1.21e-81	hmpT	-	-	S	-	-	-	membrane
KIOLHBIL_00646	7.41e-177	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
KIOLHBIL_00647	7.45e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KIOLHBIL_00648	1.19e-258	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KIOLHBIL_00649	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KIOLHBIL_00650	2.82e-105	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIOLHBIL_00651	4.82e-254	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KIOLHBIL_00652	1.26e-132	acmA	3.2.1.17	-	NU	ko:K01185,ko:K02395	-	ko00000,ko01000,ko02035	amidase activity
KIOLHBIL_00653	7.09e-181	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KIOLHBIL_00654	6.4e-173	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
KIOLHBIL_00655	9.68e-309	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KIOLHBIL_00656	1.76e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
KIOLHBIL_00657	8.25e-282	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
KIOLHBIL_00658	2.81e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
KIOLHBIL_00659	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
KIOLHBIL_00660	1.75e-80	cadC	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KIOLHBIL_00661	1.08e-116	-	-	-	L	ko:K07498	-	ko00000	Transposase
KIOLHBIL_00662	7.15e-86	isp2	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
KIOLHBIL_00663	3.86e-226	-	-	-	-	-	-	-	-
KIOLHBIL_00664	1.22e-53	-	-	-	S	-	-	-	Helix-turn-helix domain
KIOLHBIL_00665	4.82e-162	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOLHBIL_00666	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KIOLHBIL_00667	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIOLHBIL_00668	6.64e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIOLHBIL_00669	1.38e-44	-	-	-	K	-	-	-	helix-turn-helix
KIOLHBIL_00670	3.17e-199	yitS	-	-	S	-	-	-	DegV family
KIOLHBIL_00671	6.97e-121	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
KIOLHBIL_00672	5.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOLHBIL_00675	2.1e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KIOLHBIL_00676	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOLHBIL_00677	7.75e-145	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
KIOLHBIL_00678	7.76e-185	-	-	-	S	-	-	-	SseB protein N-terminal domain
KIOLHBIL_00679	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KIOLHBIL_00680	3.56e-295	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOLHBIL_00681	7.03e-64	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOLHBIL_00682	9.4e-192	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOLHBIL_00683	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOLHBIL_00684	2.83e-99	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KIOLHBIL_00685	6.89e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
KIOLHBIL_00686	2.46e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIOLHBIL_00687	1.43e-175	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KIOLHBIL_00689	1.12e-95	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
KIOLHBIL_00690	1.71e-27	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
KIOLHBIL_00692	2.5e-52	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00693	6.09e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00694	1.05e-43	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00695	7.75e-85	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
KIOLHBIL_00696	4.14e-72	badR	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
KIOLHBIL_00697	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
KIOLHBIL_00698	1.39e-298	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
KIOLHBIL_00699	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOLHBIL_00710	3.71e-57	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-Shock Protein
KIOLHBIL_00711	2.63e-44	-	-	-	K	-	-	-	Cold shock protein domain
KIOLHBIL_00712	1.84e-43	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOLHBIL_00713	1.58e-174	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOLHBIL_00714	1.2e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KIOLHBIL_00715	2.5e-231	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KIOLHBIL_00716	5.97e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KIOLHBIL_00717	2.99e-173	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
KIOLHBIL_00718	5.53e-25	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOLHBIL_00719	4.7e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KIOLHBIL_00720	3.04e-173	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KIOLHBIL_00721	3.49e-107	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
KIOLHBIL_00722	5.28e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KIOLHBIL_00723	1.84e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
KIOLHBIL_00724	1.82e-17	-	-	-	-	-	-	-	-
KIOLHBIL_00726	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIOLHBIL_00727	3.85e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KIOLHBIL_00728	3.8e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_00729	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KIOLHBIL_00730	1.85e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
KIOLHBIL_00731	6.02e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOLHBIL_00732	9.61e-247	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOLHBIL_00733	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOLHBIL_00734	3.47e-245	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
KIOLHBIL_00735	1.95e-90	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KIOLHBIL_00736	5.18e-81	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIOLHBIL_00737	9.02e-28	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIOLHBIL_00738	4.24e-126	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KIOLHBIL_00739	1.07e-32	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
KIOLHBIL_00740	4.18e-34	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
KIOLHBIL_00741	7.16e-137	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
KIOLHBIL_00742	2.47e-222	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KIOLHBIL_00743	1.98e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
KIOLHBIL_00744	2.53e-138	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOLHBIL_00745	1.41e-52	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOLHBIL_00746	2.52e-48	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOLHBIL_00747	8.66e-116	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOLHBIL_00748	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KIOLHBIL_00749	6.6e-158	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
KIOLHBIL_00750	2.12e-120	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIOLHBIL_00751	1.3e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KIOLHBIL_00752	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
KIOLHBIL_00753	3.77e-212	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
KIOLHBIL_00754	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KIOLHBIL_00756	9.47e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOLHBIL_00757	1.16e-23	-	-	-	K	-	-	-	Transcriptional
KIOLHBIL_00758	2.15e-27	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
KIOLHBIL_00763	1.9e-30	-	-	-	-	-	-	-	-
KIOLHBIL_00764	4.45e-176	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
KIOLHBIL_00765	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
KIOLHBIL_00769	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
KIOLHBIL_00770	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
KIOLHBIL_00771	5.58e-49	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00772	1.23e-24	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_00775	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIOLHBIL_00776	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KIOLHBIL_00777	4.82e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
KIOLHBIL_00778	5.78e-19	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KIOLHBIL_00779	4.7e-206	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOLHBIL_00780	3.19e-146	spi	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOLHBIL_00781	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KIOLHBIL_00782	1.91e-63	azlD	-	-	E	-	-	-	branched-chain amino acid
KIOLHBIL_00783	5.1e-148	XK27_12120	-	-	E	-	-	-	AzlC protein
KIOLHBIL_00784	1.64e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIOLHBIL_00785	1.54e-96	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KIOLHBIL_00786	3.96e-155	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
KIOLHBIL_00787	6.45e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KIOLHBIL_00788	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOLHBIL_00789	6.9e-55	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
KIOLHBIL_00790	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KIOLHBIL_00791	1.12e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
KIOLHBIL_00792	2.17e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
KIOLHBIL_00793	1.82e-17	-	-	-	-	-	-	-	-
KIOLHBIL_00794	9.51e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KIOLHBIL_00795	4.29e-57	-	-	-	L	ko:K07491	-	ko00000	Transposase
KIOLHBIL_00796	2.77e-110	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00797	2.1e-71	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00798	9.68e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00799	2.85e-41	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00800	9.42e-242	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIOLHBIL_00801	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIOLHBIL_00802	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KIOLHBIL_00803	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIOLHBIL_00804	1.09e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
KIOLHBIL_00805	2.78e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
KIOLHBIL_00806	1.33e-235	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
KIOLHBIL_00807	2.73e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KIOLHBIL_00808	2.76e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KIOLHBIL_00809	7.56e-209	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIOLHBIL_00811	1.06e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KIOLHBIL_00812	1.27e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KIOLHBIL_00813	1.83e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
KIOLHBIL_00814	8.04e-99	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
KIOLHBIL_00815	4.41e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KIOLHBIL_00816	5.24e-185	-	-	-	S	-	-	-	Macro domain protein
KIOLHBIL_00817	1.14e-14	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
KIOLHBIL_00818	3.38e-72	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
KIOLHBIL_00823	9.95e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KIOLHBIL_00824	9.03e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
KIOLHBIL_00825	9.83e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KIOLHBIL_00826	2.29e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KIOLHBIL_00827	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOLHBIL_00828	9.23e-246	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KIOLHBIL_00829	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KIOLHBIL_00830	7.21e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KIOLHBIL_00831	4.99e-180	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
KIOLHBIL_00832	4.43e-95	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
KIOLHBIL_00833	5.39e-224	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIOLHBIL_00834	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOLHBIL_00835	1.31e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
KIOLHBIL_00836	1.92e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KIOLHBIL_00837	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KIOLHBIL_00838	2.6e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KIOLHBIL_00839	5.01e-87	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIOLHBIL_00840	1.69e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KIOLHBIL_00841	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KIOLHBIL_00842	7.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIOLHBIL_00843	1.33e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KIOLHBIL_00844	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KIOLHBIL_00845	5.21e-34	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
KIOLHBIL_00846	0.000895	-	-	-	-	-	-	-	-
KIOLHBIL_00847	5.97e-73	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
KIOLHBIL_00848	8.41e-168	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KIOLHBIL_00849	3.55e-261	hasA	2.4.1.212	GT2	M	ko:K00752	-	ko00000,ko01000,ko01003,ko02000	Chitin synthase
KIOLHBIL_00850	3.76e-21	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
KIOLHBIL_00851	1.37e-55	-	-	-	L	ko:K07498	-	ko00000	Transposase
KIOLHBIL_00852	1.07e-268	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
KIOLHBIL_00853	3.73e-220	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
KIOLHBIL_00855	1.47e-90	-	-	-	L	ko:K07498	-	ko00000	Transposase
KIOLHBIL_00856	2.21e-98	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
KIOLHBIL_00857	3.34e-172	-	-	-	S	-	-	-	IstB-like ATP binding protein
KIOLHBIL_00860	2.12e-45	-	-	-	S	-	-	-	ERF superfamily
KIOLHBIL_00861	4.12e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
KIOLHBIL_00862	7.53e-94	-	-	-	S	-	-	-	Single-strand binding protein family
KIOLHBIL_00863	2.23e-97	-	-	-	S	-	-	-	magnesium ion binding
KIOLHBIL_00865	5.23e-16	-	-	-	-	-	-	-	-
KIOLHBIL_00868	5.53e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
KIOLHBIL_00869	6.66e-82	-	-	-	S	-	-	-	sequence-specific DNA binding
KIOLHBIL_00871	1.41e-39	-	-	-	-	-	-	-	-
KIOLHBIL_00872	1.81e-63	-	-	-	L	ko:K07474	-	ko00000	DNA packaging
KIOLHBIL_00873	7.83e-304	-	-	-	S	-	-	-	Terminase-like family
KIOLHBIL_00874	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KIOLHBIL_00875	3.09e-191	-	-	-	S	-	-	-	Phage Mu protein F like protein
KIOLHBIL_00876	3.05e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
KIOLHBIL_00878	6.67e-239	-	-	-	S	-	-	-	Phage major capsid protein E
KIOLHBIL_00880	1.25e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KIOLHBIL_00882	6.91e-57	-	-	-	S	-	-	-	exonuclease activity
KIOLHBIL_00883	1.05e-74	-	-	-	-	-	-	-	-
KIOLHBIL_00884	1.74e-97	-	-	-	S	-	-	-	Phage major tail protein 2
KIOLHBIL_00885	2.32e-75	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
KIOLHBIL_00886	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
KIOLHBIL_00887	1.32e-208	-	-	-	S	-	-	-	Phage tail protein
KIOLHBIL_00889	0.0	-	2.7.7.73, 2.7.7.80	-	E	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	metalloendopeptidase activity
KIOLHBIL_00890	5.1e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOLHBIL_00891	3.76e-11	-	-	-	-	-	-	-	-
KIOLHBIL_00892	3.77e-97	-	-	-	P	-	-	-	Protein conserved in bacteria
KIOLHBIL_00893	5.1e-77	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOLHBIL_00894	9.15e-55	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOLHBIL_00895	9.93e-88	yfbM	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KIOLHBIL_00896	9.16e-84	-	-	-	-	-	-	-	-
KIOLHBIL_00898	1.12e-46	-	-	-	M	ko:K07114	-	ko00000,ko02000	translation initiation factor activity
KIOLHBIL_00899	1.79e-26	-	-	-	P	-	-	-	ABC transporter transmembrane region
KIOLHBIL_00900	1.41e-107	-	-	-	F	-	-	-	cytidine deaminase activity
KIOLHBIL_00901	2.73e-213	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
KIOLHBIL_00904	2.31e-200	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOLHBIL_00905	2.93e-32	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOLHBIL_00906	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KIOLHBIL_00907	1.2e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
KIOLHBIL_00908	0.0	-	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
KIOLHBIL_00909	1.09e-143	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_00910	3.49e-217	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
KIOLHBIL_00911	2.69e-178	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_00912	4.54e-124	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOLHBIL_00913	2.17e-84	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
KIOLHBIL_00914	2.05e-163	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
KIOLHBIL_00915	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIOLHBIL_00916	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KIOLHBIL_00917	6.89e-89	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00918	1.38e-16	-	-	-	-	-	-	-	-
KIOLHBIL_00919	5.31e-120	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
KIOLHBIL_00920	1.36e-112	alkD	-	-	L	-	-	-	Dna alkylation repair
KIOLHBIL_00921	2.9e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIOLHBIL_00922	6.31e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIOLHBIL_00923	1.39e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KIOLHBIL_00924	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KIOLHBIL_00925	2.9e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIOLHBIL_00926	3.44e-117	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOLHBIL_00927	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOLHBIL_00930	2.66e-74	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
KIOLHBIL_00931	4.39e-306	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIOLHBIL_00933	1.03e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOLHBIL_00934	1.27e-53	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
KIOLHBIL_00935	1.15e-110	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
KIOLHBIL_00936	3.78e-107	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOLHBIL_00937	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
KIOLHBIL_00938	0.0	noxE	-	-	P	-	-	-	NADH oxidase
KIOLHBIL_00939	2.06e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KIOLHBIL_00940	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOLHBIL_00941	8.52e-167	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
KIOLHBIL_00942	5.63e-90	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
KIOLHBIL_00943	2.94e-213	ypuA	-	-	S	-	-	-	secreted protein
KIOLHBIL_00944	1.28e-35	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
KIOLHBIL_00945	3.37e-92	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
KIOLHBIL_00947	8.44e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOLHBIL_00948	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOLHBIL_00949	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KIOLHBIL_00950	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KIOLHBIL_00951	1.22e-270	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
KIOLHBIL_00952	5.09e-283	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
KIOLHBIL_00953	3.31e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
KIOLHBIL_00954	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIOLHBIL_00955	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KIOLHBIL_00956	2.02e-39	-	6.3.2.2, 6.3.2.4	-	F	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	ko00000,ko00001,ko00002,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KIOLHBIL_00957	4.74e-245	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KIOLHBIL_00958	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KIOLHBIL_00959	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
KIOLHBIL_00960	4.3e-169	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
KIOLHBIL_00961	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIOLHBIL_00962	1.02e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KIOLHBIL_00963	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
KIOLHBIL_00964	1.15e-160	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KIOLHBIL_00965	1.47e-217	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_00966	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIOLHBIL_00967	2.02e-92	mesH	-	-	S	-	-	-	GtrA-like protein
KIOLHBIL_00968	4.3e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KIOLHBIL_00969	3.29e-189	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KIOLHBIL_00970	1.99e-135	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
KIOLHBIL_00971	3.42e-261	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
KIOLHBIL_00972	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIOLHBIL_00973	4.07e-144	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIOLHBIL_00974	3.31e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KIOLHBIL_00976	1.62e-277	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
KIOLHBIL_00977	7.79e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KIOLHBIL_00978	8.04e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KIOLHBIL_00979	1.71e-158	-	-	-	S	-	-	-	tigr01906
KIOLHBIL_00980	2.41e-181	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
KIOLHBIL_00981	3.95e-17	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
KIOLHBIL_00982	1.88e-113	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
KIOLHBIL_00983	8.38e-43	XK27_08085	-	-	-	-	-	-	-
KIOLHBIL_00984	5.56e-99	-	-	-	L	-	-	-	Transposase
KIOLHBIL_00985	1.29e-72	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_00986	2.77e-43	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00987	7.42e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_00989	2.37e-249	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIOLHBIL_00990	7.47e-234	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KIOLHBIL_00991	8.39e-151	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KIOLHBIL_00992	1.19e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KIOLHBIL_00993	3.35e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
KIOLHBIL_00994	3.32e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIOLHBIL_00995	9.32e-164	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KIOLHBIL_00996	2.57e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KIOLHBIL_00997	4.23e-80	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KIOLHBIL_00998	5.16e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
KIOLHBIL_00999	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KIOLHBIL_01000	2.86e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIOLHBIL_01001	6.65e-152	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
KIOLHBIL_01002	1.04e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KIOLHBIL_01003	1.28e-178	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOLHBIL_01004	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
KIOLHBIL_01005	6.44e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIOLHBIL_01006	2.81e-232	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIOLHBIL_01007	9.02e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
KIOLHBIL_01008	3.81e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIOLHBIL_01011	1.29e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIOLHBIL_01012	1.72e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
KIOLHBIL_01013	1.64e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KIOLHBIL_01014	2.83e-203	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KIOLHBIL_01015	1.72e-94	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KIOLHBIL_01016	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KIOLHBIL_01017	2.67e-187	WQ51_01275	-	-	S	-	-	-	DegV family
KIOLHBIL_01018	2.56e-186	ypmR	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KIOLHBIL_01019	1.72e-123	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_01020	1.54e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KIOLHBIL_01022	2.31e-230	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
KIOLHBIL_01023	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KIOLHBIL_01024	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIOLHBIL_01025	7.51e-242	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KIOLHBIL_01026	1.64e-57	ysdA	-	-	L	-	-	-	Membrane
KIOLHBIL_01027	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIOLHBIL_01028	9.26e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIOLHBIL_01029	1.99e-194	XK27_00020	-	-	J	-	-	-	Belongs to the SUA5 family
KIOLHBIL_01030	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KIOLHBIL_01031	1.04e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KIOLHBIL_01032	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KIOLHBIL_01034	9.37e-11	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01036	1.12e-33	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01037	4.47e-39	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01039	5.6e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4649)
KIOLHBIL_01040	1.68e-229	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
KIOLHBIL_01041	9.64e-191	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOLHBIL_01042	1.09e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_01043	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOLHBIL_01044	1.84e-194	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
KIOLHBIL_01045	2.2e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
KIOLHBIL_01047	4.07e-97	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KIOLHBIL_01048	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
KIOLHBIL_01049	5.18e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
KIOLHBIL_01050	4.14e-277	-	-	-	P	-	-	-	chloride
KIOLHBIL_01051	5.73e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KIOLHBIL_01053	6.46e-128	-	6.3.2.2	-	H	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	ergothioneine biosynthetic process
KIOLHBIL_01054	2.98e-77	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
KIOLHBIL_01055	2.69e-16	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
KIOLHBIL_01056	7.69e-18	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOLHBIL_01057	2.14e-141	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOLHBIL_01058	2.13e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
KIOLHBIL_01059	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOLHBIL_01060	1.57e-80	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIOLHBIL_01061	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIOLHBIL_01062	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KIOLHBIL_01063	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIOLHBIL_01064	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KIOLHBIL_01065	3.68e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KIOLHBIL_01066	3.45e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KIOLHBIL_01067	2e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
KIOLHBIL_01068	9.94e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIOLHBIL_01069	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIOLHBIL_01070	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIOLHBIL_01071	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIOLHBIL_01072	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIOLHBIL_01073	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIOLHBIL_01074	3.99e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIOLHBIL_01075	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIOLHBIL_01076	7.55e-53	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIOLHBIL_01077	4.36e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KIOLHBIL_01078	3.58e-93	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIOLHBIL_01079	1.1e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIOLHBIL_01080	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIOLHBIL_01081	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIOLHBIL_01082	7.19e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIOLHBIL_01083	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KIOLHBIL_01084	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KIOLHBIL_01085	3.17e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIOLHBIL_01086	7.41e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KIOLHBIL_01087	1.78e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KIOLHBIL_01088	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
KIOLHBIL_01089	4e-46	-	-	-	S	-	-	-	MORN repeat protein
KIOLHBIL_01090	8.96e-104	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIOLHBIL_01091	1.93e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIOLHBIL_01092	6.93e-112	flaR	-	-	F	-	-	-	topology modulation protein
KIOLHBIL_01093	9.41e-65	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	purine nucleotide biosynthetic process
KIOLHBIL_01094	3.12e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIOLHBIL_01095	9.01e-81	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
KIOLHBIL_01096	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIOLHBIL_01097	1.43e-109	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KIOLHBIL_01098	3.4e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
KIOLHBIL_01100	3.75e-56	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOLHBIL_01101	1.21e-27	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOLHBIL_01104	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KIOLHBIL_01105	6.01e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
KIOLHBIL_01106	5.91e-159	-	-	-	S	-	-	-	Pfam PF06570
KIOLHBIL_01108	2.03e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIOLHBIL_01109	2.07e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOLHBIL_01110	3.11e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KIOLHBIL_01111	3.9e-50	XK27_05745	-	-	-	-	-	-	-
KIOLHBIL_01112	5.55e-292	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
KIOLHBIL_01114	1.4e-43	-	-	-	L	-	-	-	nUDIX hydrolase
KIOLHBIL_01118	9.11e-132	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOLHBIL_01119	4.3e-114	-	-	-	M	-	-	-	ATP-grasp domain
KIOLHBIL_01120	1.57e-230	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KIOLHBIL_01121	1.45e-43	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
KIOLHBIL_01122	3.11e-231	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01123	8.96e-126	fic	-	-	D	ko:K04095	-	ko00000,ko03036	nucleotidyltransferase activity
KIOLHBIL_01124	1e-35	-	-	-	-	-	-	-	-
KIOLHBIL_01125	5.06e-260	-	-	-	S	-	-	-	Phage integrase family
KIOLHBIL_01126	6.06e-46	-	-	-	S	-	-	-	Host cell surface-exposed lipoprotein
KIOLHBIL_01127	5.26e-54	-	-	-	E	-	-	-	Zn peptidase
KIOLHBIL_01128	1.43e-69	-	-	-	-	-	-	-	-
KIOLHBIL_01129	2.28e-40	-	-	-	-	-	-	-	-
KIOLHBIL_01133	1.56e-166	-	-	-	S	-	-	-	DNA binding
KIOLHBIL_01136	4.71e-09	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KIOLHBIL_01139	8.58e-67	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOLHBIL_01140	4.28e-169	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOLHBIL_01141	7.33e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KIOLHBIL_01142	1.45e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOLHBIL_01143	3.59e-127	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
KIOLHBIL_01145	4.42e-41	-	-	-	S	-	-	-	Bacterial epsilon antitoxin
KIOLHBIL_01146	2.56e-201	-	-	-	L	-	-	-	Replication protein
KIOLHBIL_01147	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	P-type ATPase
KIOLHBIL_01148	1.01e-251	-	-	-	L	ko:K07481	-	ko00000	transposase, IS4 family
KIOLHBIL_01149	1.76e-232	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
KIOLHBIL_01150	0.0	-	-	-	-	-	-	-	-
KIOLHBIL_01151	2.6e-156	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
KIOLHBIL_01152	9.96e-135	-	-	-	-	-	-	-	-
KIOLHBIL_01153	8.01e-175	-	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_01154	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOLHBIL_01155	1.8e-19	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
KIOLHBIL_01156	5.81e-226	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KIOLHBIL_01157	7.6e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KIOLHBIL_01158	2.22e-185	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KIOLHBIL_01159	6.06e-97	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
KIOLHBIL_01160	3.09e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
KIOLHBIL_01161	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KIOLHBIL_01162	1.34e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KIOLHBIL_01163	6.73e-145	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
KIOLHBIL_01164	1.22e-281	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
KIOLHBIL_01165	3.17e-150	pppA	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KIOLHBIL_01166	5.49e-119	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KIOLHBIL_01167	5.82e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KIOLHBIL_01168	1.58e-37	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
KIOLHBIL_01169	1.18e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KIOLHBIL_01170	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KIOLHBIL_01171	2.68e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
KIOLHBIL_01172	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIOLHBIL_01173	5.46e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIOLHBIL_01174	7.09e-238	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KIOLHBIL_01175	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KIOLHBIL_01176	2.64e-303	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIOLHBIL_01177	3.98e-159	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KIOLHBIL_01178	2.85e-122	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KIOLHBIL_01179	6.28e-47	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
KIOLHBIL_01180	1.18e-184	ylmH	-	-	T	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	S4 RNA-binding domain
KIOLHBIL_01181	8.47e-186	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division protein DivIVA
KIOLHBIL_01182	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIOLHBIL_01183	3.13e-08	-	-	-	-	-	-	-	-
KIOLHBIL_01184	1.43e-290	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
KIOLHBIL_01185	1.39e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
KIOLHBIL_01186	9.71e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIOLHBIL_01187	1.01e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
KIOLHBIL_01188	2.67e-195	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
KIOLHBIL_01189	5.3e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KIOLHBIL_01190	2.65e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KIOLHBIL_01191	5.57e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIOLHBIL_01192	9.12e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KIOLHBIL_01193	1.2e-140	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KIOLHBIL_01194	7.18e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIOLHBIL_01195	1.23e-227	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
KIOLHBIL_01196	2.31e-130	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
KIOLHBIL_01197	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01198	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01199	3.08e-14	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KIOLHBIL_01200	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOLHBIL_01201	5.94e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
KIOLHBIL_01202	4.98e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOLHBIL_01203	1.09e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KIOLHBIL_01204	2.59e-113	-	-	-	L	ko:K07497	-	ko00000	Transposase and inactivated derivatives
KIOLHBIL_01205	1.17e-68	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_01206	2.82e-29	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01207	3.83e-61	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOLHBIL_01208	2.7e-40	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_01209	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIOLHBIL_01210	2.22e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
KIOLHBIL_01211	8.87e-306	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KIOLHBIL_01212	2.66e-307	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
KIOLHBIL_01213	1.94e-05	-	-	-	-	-	-	-	-
KIOLHBIL_01214	3.34e-80	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KIOLHBIL_01215	1.59e-51	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KIOLHBIL_01216	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIOLHBIL_01217	4.43e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KIOLHBIL_01218	1.06e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KIOLHBIL_01219	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_01220	7.77e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KIOLHBIL_01221	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIOLHBIL_01222	1.08e-170	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KIOLHBIL_01223	2.95e-267	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KIOLHBIL_01224	7.3e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIOLHBIL_01225	1.05e-154	yveI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KIOLHBIL_01229	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOLHBIL_01230	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
KIOLHBIL_01231	3.8e-193	XK27_10395	-	-	S	-	-	-	membrane
KIOLHBIL_01232	4.75e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
KIOLHBIL_01233	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KIOLHBIL_01234	2.24e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIOLHBIL_01235	2.4e-65	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
KIOLHBIL_01236	1.45e-297	albE	-	-	S	-	-	-	Peptidase M16
KIOLHBIL_01237	2.1e-306	ymfH	-	-	S	-	-	-	Peptidase M16
KIOLHBIL_01238	8.84e-185	ymfM	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
KIOLHBIL_01239	5.4e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIOLHBIL_01240	5.46e-195	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOLHBIL_01241	2.6e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOLHBIL_01242	4.95e-176	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOLHBIL_01243	5.36e-120	lytE	-	-	M	-	-	-	LysM domain protein
KIOLHBIL_01244	3.12e-113	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
KIOLHBIL_01245	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
KIOLHBIL_01246	3.66e-276	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIOLHBIL_01247	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KIOLHBIL_01248	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KIOLHBIL_01249	1.24e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KIOLHBIL_01250	1.29e-312	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KIOLHBIL_01251	3.05e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
KIOLHBIL_01252	5.92e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIOLHBIL_01253	3.47e-12	-	-	-	-	-	-	-	-
KIOLHBIL_01254	3.12e-70	ypaA	-	-	S	ko:K08987	-	ko00000	membrane
KIOLHBIL_01255	4.65e-123	XK27_06935	-	-	K	-	-	-	transcriptional regulator
KIOLHBIL_01256	2.37e-268	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
KIOLHBIL_01257	2.02e-147	-	-	-	S	-	-	-	Putative adhesin
KIOLHBIL_01258	5.06e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
KIOLHBIL_01259	1.91e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
KIOLHBIL_01260	2.32e-64	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
KIOLHBIL_01261	2.9e-18	XK27_06885	-	-	L	-	-	-	hydrolase
KIOLHBIL_01262	2.91e-69	XK27_06885	-	-	L	-	-	-	hydrolase
KIOLHBIL_01263	1.17e-34	-	-	-	K	-	-	-	CsbD-like
KIOLHBIL_01264	2.34e-111	-	-	-	M	-	-	-	Protein conserved in bacteria
KIOLHBIL_01265	7.53e-33	-	-	-	S	-	-	-	Small integral membrane protein
KIOLHBIL_01266	2.67e-131	-	-	-	-	-	-	-	-
KIOLHBIL_01267	1.61e-44	ytgB	-	-	S	-	-	-	Membrane
KIOLHBIL_01269	9.84e-123	-	-	-	S	-	-	-	Hydrophobic domain protein
KIOLHBIL_01270	8.98e-105	yegS	-	-	I	-	-	-	Diacylglycerol kinase
KIOLHBIL_01271	2.17e-58	yegS	-	-	I	-	-	-	Diacylglycerol kinase
KIOLHBIL_01273	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KIOLHBIL_01274	4.33e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KIOLHBIL_01275	4.8e-45	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KIOLHBIL_01276	6.98e-149	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KIOLHBIL_01277	6.78e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KIOLHBIL_01279	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KIOLHBIL_01280	1.1e-208	XK27_01785	-	-	S	-	-	-	cog cog1284
KIOLHBIL_01281	1.62e-187	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KIOLHBIL_01282	2.18e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOLHBIL_01283	1.87e-118	-	-	-	K	-	-	-	acetyltransferase
KIOLHBIL_01284	7.68e-20	-	-	-	-	-	-	-	-
KIOLHBIL_01285	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KIOLHBIL_01286	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01287	2.7e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KIOLHBIL_01288	8.4e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIOLHBIL_01289	3.4e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KIOLHBIL_01290	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KIOLHBIL_01291	3.74e-303	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
KIOLHBIL_01293	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KIOLHBIL_01294	3.16e-294	-	-	-	C	ko:K06871	-	ko00000	Radical SAM
KIOLHBIL_01296	2.81e-166	Z012_04635	-	-	K	-	-	-	sequence-specific DNA binding
KIOLHBIL_01297	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
KIOLHBIL_01298	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
KIOLHBIL_01299	7.46e-200	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
KIOLHBIL_01301	3.13e-17	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
KIOLHBIL_01311	2.12e-163	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOLHBIL_01313	5.78e-192	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIOLHBIL_01314	1.46e-207	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01315	7.96e-169	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01316	7.33e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
KIOLHBIL_01317	4.78e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KIOLHBIL_01318	9.01e-121	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
KIOLHBIL_01319	7.91e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIOLHBIL_01320	6.55e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KIOLHBIL_01321	1.51e-236	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
KIOLHBIL_01322	9e-127	mraW1	-	-	J	-	-	-	(SAM)-dependent
KIOLHBIL_01324	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
KIOLHBIL_01325	1.29e-185	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01326	2.02e-304	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
KIOLHBIL_01327	6.7e-200	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOLHBIL_01330	5.1e-97	XK27_03180	-	-	T	-	-	-	universal stress protein
KIOLHBIL_01331	2.61e-303	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KIOLHBIL_01332	6.34e-182	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KIOLHBIL_01333	1.75e-129	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
KIOLHBIL_01334	8.06e-198	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
KIOLHBIL_01335	9.73e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOLHBIL_01336	3.9e-294	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOLHBIL_01337	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOLHBIL_01338	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KIOLHBIL_01339	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOLHBIL_01340	2.6e-62	-	-	-	-	-	-	-	-
KIOLHBIL_01341	1.37e-194	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIOLHBIL_01342	1.84e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
KIOLHBIL_01343	2.78e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KIOLHBIL_01344	1.59e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
KIOLHBIL_01345	3.06e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIOLHBIL_01346	2.01e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
KIOLHBIL_01347	9.81e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KIOLHBIL_01348	2.78e-179	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
KIOLHBIL_01349	1.03e-261	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KIOLHBIL_01350	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
KIOLHBIL_01352	7.51e-80	-	-	-	-	-	-	-	-
KIOLHBIL_01353	9.81e-22	-	-	-	S	-	-	-	CD20-like family
KIOLHBIL_01354	3.91e-14	-	-	-	-	-	-	-	-
KIOLHBIL_01355	3.05e-95	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KIOLHBIL_01356	1.5e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_01357	4.45e-231	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KIOLHBIL_01358	8.46e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
KIOLHBIL_01359	3.58e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KIOLHBIL_01361	9.59e-289	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
KIOLHBIL_01362	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
KIOLHBIL_01363	3.02e-83	XK27_02560	-	-	S	-	-	-	cog cog2151
KIOLHBIL_01364	1.41e-80	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
KIOLHBIL_01365	4.56e-136	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KIOLHBIL_01366	8.77e-88	-	-	-	K	-	-	-	transcriptional regulator, MerR family
KIOLHBIL_01367	8.5e-49	-	-	-	L	-	-	-	transposase activity
KIOLHBIL_01368	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIOLHBIL_01369	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KIOLHBIL_01370	7.4e-70	-	-	-	-	-	-	-	-
KIOLHBIL_01371	9.49e-57	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
KIOLHBIL_01372	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIOLHBIL_01373	5.83e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
KIOLHBIL_01374	9e-230	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIOLHBIL_01375	5.36e-171	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
KIOLHBIL_01376	3.75e-129	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
KIOLHBIL_01377	6.77e-289	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KIOLHBIL_01378	4.31e-184	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KIOLHBIL_01379	1.49e-97	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor, CopY TcrY family
KIOLHBIL_01380	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KIOLHBIL_01381	7.81e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
KIOLHBIL_01382	3.92e-247	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KIOLHBIL_01383	8.58e-149	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01384	4.02e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01385	2.01e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01386	9.46e-200	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOLHBIL_01389	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KIOLHBIL_01390	1.15e-155	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
KIOLHBIL_01391	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIOLHBIL_01392	3.49e-254	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
KIOLHBIL_01393	1.39e-198	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOLHBIL_01394	6.49e-129	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
KIOLHBIL_01395	1.07e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
KIOLHBIL_01396	2.92e-203	corA	-	-	P	-	-	-	CorA-like protein
KIOLHBIL_01397	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KIOLHBIL_01398	1.18e-55	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
KIOLHBIL_01399	1.75e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
KIOLHBIL_01400	1.08e-115	nodB3	-	-	G	-	-	-	deacetylase
KIOLHBIL_01401	2.5e-71	nodB3	-	-	G	-	-	-	polysaccharide deacetylase
KIOLHBIL_01402	1.76e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KIOLHBIL_01404	2.65e-126	-	-	-	-	-	-	-	-
KIOLHBIL_01405	4.99e-70	-	-	-	S	-	-	-	ABC-2 type transporter
KIOLHBIL_01406	1.82e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KIOLHBIL_01408	6.68e-176	-	-	-	C	-	-	-	Iron-sulfur cluster-binding domain
KIOLHBIL_01409	2.42e-140	pqqE	-	-	C	-	-	-	4Fe-4S single cluster domain
KIOLHBIL_01411	1.26e-138	gadR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KIOLHBIL_01412	4.8e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
KIOLHBIL_01413	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KIOLHBIL_01414	4.29e-295	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOLHBIL_01415	3.77e-124	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
KIOLHBIL_01416	1.29e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
KIOLHBIL_01417	2.86e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KIOLHBIL_01418	8.58e-205	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KIOLHBIL_01419	2.79e-111	ccl	-	-	S	-	-	-	cog cog4708
KIOLHBIL_01420	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIOLHBIL_01421	7.79e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KIOLHBIL_01422	1.22e-97	-	-	-	S	-	-	-	QueT transporter
KIOLHBIL_01423	9.9e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KIOLHBIL_01425	8.93e-218	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
KIOLHBIL_01426	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KIOLHBIL_01427	9.09e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KIOLHBIL_01428	1.93e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOLHBIL_01429	0.0	ydaO	-	-	E	-	-	-	amino acid
KIOLHBIL_01430	1.17e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
KIOLHBIL_01431	1.29e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KIOLHBIL_01432	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01433	1.05e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KIOLHBIL_01434	3.78e-112	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KIOLHBIL_01435	3.1e-219	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
KIOLHBIL_01436	1.38e-272	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KIOLHBIL_01437	2e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
KIOLHBIL_01438	2.09e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
KIOLHBIL_01439	3.44e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
KIOLHBIL_01440	1.85e-05	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
KIOLHBIL_01441	1.69e-29	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
KIOLHBIL_01442	2.4e-108	XK27_08050	-	-	O	-	-	-	stress-induced mitochondrial fusion
KIOLHBIL_01443	1.61e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
KIOLHBIL_01444	1.8e-101	-	-	-	GK	-	-	-	ROK family
KIOLHBIL_01445	3.61e-267	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KIOLHBIL_01446	2.3e-135	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
KIOLHBIL_01447	2.15e-280	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOLHBIL_01448	3.47e-72	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
KIOLHBIL_01449	1.02e-78	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KIOLHBIL_01451	2.14e-76	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
KIOLHBIL_01452	4.46e-151	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	effector of murein hydrolase
KIOLHBIL_01453	1.07e-141	-	-	-	S	-	-	-	IA, variant 1
KIOLHBIL_01454	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOLHBIL_01455	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KIOLHBIL_01456	4.14e-146	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
KIOLHBIL_01457	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KIOLHBIL_01458	2.97e-210	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_01459	1.19e-72	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_01460	7.34e-142	csn2	-	-	S	ko:K19137	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csn2)
KIOLHBIL_01470	2.71e-72	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K07317	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
KIOLHBIL_01471	5.2e-107	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOLHBIL_01472	2.7e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
KIOLHBIL_01473	4.66e-07	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
KIOLHBIL_01474	7.53e-99	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
KIOLHBIL_01475	9.76e-87	XK27_10720	-	-	D	-	-	-	peptidase activity
KIOLHBIL_01476	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KIOLHBIL_01479	2.62e-218	yeiH	-	-	S	-	-	-	Membrane
KIOLHBIL_01480	1.78e-26	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
KIOLHBIL_01481	4.28e-107	mur1	-	-	NU	ko:K02395	-	ko00000,ko02035	amidase activity
KIOLHBIL_01482	8.72e-122	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_01483	2.18e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator
KIOLHBIL_01484	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIOLHBIL_01485	7.71e-77	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
KIOLHBIL_01486	3.92e-134	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01487	1.51e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01488	1.58e-202	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOLHBIL_01489	4.97e-55	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOLHBIL_01490	2.31e-141	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOLHBIL_01491	2.18e-10	-	-	-	-	-	-	-	-
KIOLHBIL_01492	2.8e-36	-	-	-	-	-	-	-	-
KIOLHBIL_01493	1.28e-78	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOLHBIL_01494	1.67e-141	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOLHBIL_01496	2.11e-27	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
KIOLHBIL_01497	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KIOLHBIL_01498	1.75e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
KIOLHBIL_01499	9e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KIOLHBIL_01500	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIOLHBIL_01501	5.65e-113	niaX	-	-	-	ko:K16788	-	ko00000,ko02000	-
KIOLHBIL_01502	2.24e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
KIOLHBIL_01503	3.55e-163	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
KIOLHBIL_01504	9.86e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KIOLHBIL_01505	4.11e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOLHBIL_01506	5.35e-217	-	-	-	GK	-	-	-	ROK family
KIOLHBIL_01507	4.04e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KIOLHBIL_01508	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIOLHBIL_01509	1.03e-198	-	-	-	S	-	-	-	TraX protein
KIOLHBIL_01510	2.93e-157	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOLHBIL_01511	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
KIOLHBIL_01512	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KIOLHBIL_01513	5.35e-105	XK27_05470	-	-	E	-	-	-	Methionine synthase
KIOLHBIL_01514	1.04e-27	XK27_05470	-	-	E	-	-	-	Methionine synthase
KIOLHBIL_01515	1.08e-95	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KIOLHBIL_01516	1.17e-61	pspE	-	-	P	ko:K03972	-	ko00000	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIOLHBIL_01517	3.14e-71	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
KIOLHBIL_01518	1.64e-52	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
KIOLHBIL_01520	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIOLHBIL_01523	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KIOLHBIL_01524	1.34e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
KIOLHBIL_01525	9.42e-116	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01526	2.25e-142	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOLHBIL_01527	9.28e-15	-	-	-	-	-	-	-	-
KIOLHBIL_01528	2.69e-127	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
KIOLHBIL_01529	1.29e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KIOLHBIL_01530	3.37e-268	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KIOLHBIL_01531	1.61e-249	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
KIOLHBIL_01532	2.92e-11	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
KIOLHBIL_01533	5.62e-24	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOLHBIL_01534	2.43e-103	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOLHBIL_01537	2.4e-84	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOLHBIL_01538	1.22e-91	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOLHBIL_01539	6.95e-152	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
KIOLHBIL_01540	2.48e-09	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
KIOLHBIL_01541	3.53e-24	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
KIOLHBIL_01542	2.32e-93	dinF	-	-	V	-	-	-	Mate efflux family protein
KIOLHBIL_01543	1.77e-47	dinF	-	-	V	-	-	-	drug transmembrane transporter activity
KIOLHBIL_01545	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
KIOLHBIL_01547	1.48e-60	-	-	-	S	-	-	-	TraX protein
KIOLHBIL_01548	2.1e-73	-	-	-	S	-	-	-	TraX protein
KIOLHBIL_01549	2.04e-123	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
KIOLHBIL_01550	8.38e-190	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KIOLHBIL_01551	6.78e-223	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIOLHBIL_01552	1.02e-235	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_01553	2.91e-72	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOLHBIL_01554	9.03e-173	cas6	-	-	S	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR-associated endoribonuclease Cas6
KIOLHBIL_01555	0.0	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
KIOLHBIL_01556	1.29e-83	csm2	-	-	L	ko:K19138	-	ko00000,ko02048	Csm2 Type III-A
KIOLHBIL_01557	1.62e-150	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
KIOLHBIL_01558	2.1e-215	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
KIOLHBIL_01559	1.5e-257	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm5 family
KIOLHBIL_01560	2.77e-142	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOLHBIL_01561	8.11e-185	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOLHBIL_01562	8.02e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KIOLHBIL_01563	6.16e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIOLHBIL_01564	7.71e-64	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KIOLHBIL_01565	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	transporter
KIOLHBIL_01566	1.67e-134	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KIOLHBIL_01567	4.06e-90	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOLHBIL_01568	3.24e-62	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOLHBIL_01569	4.52e-87	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01570	7.18e-14	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01571	6.47e-09	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_01572	3.56e-290	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_01573	1.31e-51	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOLHBIL_01575	6.9e-22	bglC	-	-	K	-	-	-	Transcriptional regulator
KIOLHBIL_01576	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIOLHBIL_01577	8.25e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
KIOLHBIL_01578	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KIOLHBIL_01579	2.95e-307	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
KIOLHBIL_01580	1.17e-73	-	-	-	Q	-	-	-	phosphatase activity
KIOLHBIL_01581	5.48e-79	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KIOLHBIL_01582	8.57e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KIOLHBIL_01583	6.68e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
KIOLHBIL_01584	2.63e-16	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
KIOLHBIL_01585	4.06e-260	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
KIOLHBIL_01586	5.24e-195	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIOLHBIL_01587	8.62e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KIOLHBIL_01588	7.52e-95	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KIOLHBIL_01589	1.99e-58	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KIOLHBIL_01590	8.38e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
KIOLHBIL_01591	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KIOLHBIL_01592	9.81e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
KIOLHBIL_01593	4.63e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KIOLHBIL_01594	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
KIOLHBIL_01595	5.27e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOLHBIL_01596	1.75e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOLHBIL_01597	1.1e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KIOLHBIL_01598	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KIOLHBIL_01599	5.37e-249	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KIOLHBIL_01600	6.19e-239	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KIOLHBIL_01604	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KIOLHBIL_01605	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
KIOLHBIL_01606	3.73e-49	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOLHBIL_01607	6.6e-25	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOLHBIL_01608	4.56e-221	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOLHBIL_01609	7.89e-244	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01610	4.79e-34	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
KIOLHBIL_01611	4.51e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIOLHBIL_01612	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
KIOLHBIL_01613	6.81e-293	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
KIOLHBIL_01614	1.37e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
KIOLHBIL_01615	7.97e-231	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
KIOLHBIL_01616	1.75e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01617	6.34e-214	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIOLHBIL_01618	4.1e-210	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIOLHBIL_01619	4.58e-67	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01620	9.6e-46	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01621	1.51e-69	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01622	1.04e-58	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01623	4.86e-112	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOLHBIL_01624	3.89e-207	-	-	-	S	-	-	-	peptidoglycan catabolic process
KIOLHBIL_01625	4.05e-254	-	-	-	-	-	-	-	-
KIOLHBIL_01629	4.6e-28	hol	-	-	S	-	-	-	COG5546 Small integral membrane protein
KIOLHBIL_01630	5.85e-138	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
KIOLHBIL_01631	3e-66	-	-	-	S	-	-	-	Streptococcus thermophilus bacteriophage Gp111 protein
KIOLHBIL_01636	1.9e-27	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KIOLHBIL_01637	3.68e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIOLHBIL_01638	1.3e-115	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KIOLHBIL_01639	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOLHBIL_01640	2.38e-223	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIOLHBIL_01641	5.75e-267	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIOLHBIL_01642	4.24e-18	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
KIOLHBIL_01643	2.57e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOLHBIL_01645	2.06e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOLHBIL_01646	4.09e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
KIOLHBIL_01647	3.92e-176	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KIOLHBIL_01648	3.52e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
KIOLHBIL_01649	2.38e-158	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOLHBIL_01650	8.04e-193	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIOLHBIL_01651	1.82e-178	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01652	2.49e-166	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOLHBIL_01653	5.25e-313	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOLHBIL_01654	1.77e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
KIOLHBIL_01655	2.47e-292	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
KIOLHBIL_01656	9.38e-188	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
KIOLHBIL_01657	9.59e-67	XK27_00115	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOLHBIL_01658	1.62e-87	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KIOLHBIL_01659	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
KIOLHBIL_01660	1.38e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KIOLHBIL_01661	7.13e-262	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KIOLHBIL_01662	5.35e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KIOLHBIL_01663	6.01e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
KIOLHBIL_01664	4.01e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KIOLHBIL_01665	1.18e-118	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
KIOLHBIL_01666	3.5e-231	XK27_05220	-	-	S	-	-	-	permease
KIOLHBIL_01667	1.34e-285	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
KIOLHBIL_01668	2.67e-125	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOLHBIL_01669	6.13e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KIOLHBIL_01670	5.35e-118	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
KIOLHBIL_01671	1.47e-59	XK27_09115	-	-	M	-	-	-	LysM domain
KIOLHBIL_01672	8.33e-156	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KIOLHBIL_01673	3.15e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIOLHBIL_01674	7.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KIOLHBIL_01675	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIOLHBIL_01676	3.41e-112	XK27_03610	-	-	K	-	-	-	Gnat family
KIOLHBIL_01677	6.59e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KIOLHBIL_01678	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
KIOLHBIL_01679	5.59e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
KIOLHBIL_01680	1.53e-44	-	-	-	V	-	-	-	Glucan-binding protein C
KIOLHBIL_01681	6.71e-12	-	-	-	V	-	-	-	Glucan-binding protein C
KIOLHBIL_01682	8.33e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIOLHBIL_01683	2.7e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KIOLHBIL_01684	1.48e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
KIOLHBIL_01685	2.92e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KIOLHBIL_01686	1.97e-151	clcA2	-	-	P	-	-	-	chloride
KIOLHBIL_01687	9.96e-83	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
KIOLHBIL_01689	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
KIOLHBIL_01690	0.0	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KIOLHBIL_01691	2.13e-171	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
KIOLHBIL_01692	7.53e-145	capA	-	-	M	-	-	-	biosynthesis protein
KIOLHBIL_01693	9.06e-154	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
KIOLHBIL_01694	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KIOLHBIL_01695	1.26e-15	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
KIOLHBIL_01696	6.87e-32	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
KIOLHBIL_01697	6.68e-134	lspL	5.1.3.6	-	M	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	epimerase dehydratase
KIOLHBIL_01698	4.92e-48	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KIOLHBIL_01699	6.22e-212	lspL	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Polysaccharide biosynthesis protein
KIOLHBIL_01700	1.81e-275	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KIOLHBIL_01701	1.98e-22	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIOLHBIL_01702	1.31e-29	-	-	-	M	-	-	-	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIOLHBIL_01703	8.3e-147	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
KIOLHBIL_01704	1.81e-169	-	-	-	S	-	-	-	Protein conserved in bacteria
KIOLHBIL_01705	1.98e-09	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIOLHBIL_01706	1.04e-15	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIOLHBIL_01707	4.29e-79	-	-	-	M	-	-	-	Glycosyl transferase family 2
KIOLHBIL_01708	7.25e-80	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KIOLHBIL_01710	6.66e-57	-	-	-	V	-	-	-	Glycosyl transferase, family 2
KIOLHBIL_01711	6.1e-112	-	-	-	M	-	-	-	TupA-like ATPgrasp
KIOLHBIL_01712	9.71e-241	-	-	-	S	-	-	-	polysaccharide biosynthetic process
KIOLHBIL_01713	2.26e-204	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_01714	3.94e-56	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_01715	6.98e-124	-	-	-	V	-	-	-	VanZ like family
KIOLHBIL_01716	1.17e-19	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOLHBIL_01717	1.55e-91	supH	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
KIOLHBIL_01718	1.18e-110	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
KIOLHBIL_01719	2.04e-255	XK27_12525	-	-	S	-	-	-	hmm pf01594
KIOLHBIL_01720	1.54e-35	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
KIOLHBIL_01721	8.23e-85	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOLHBIL_01722	3.17e-54	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
KIOLHBIL_01723	1.99e-48	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOLHBIL_01724	8.7e-53	-	-	-	S	-	-	-	granule-associated protein
KIOLHBIL_01725	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
KIOLHBIL_01726	1.17e-110	-	-	-	E	-	-	-	GDSL-like protein
KIOLHBIL_01727	1.58e-202	-	-	-	S	-	-	-	Phospholipase, patatin family
KIOLHBIL_01728	6.48e-215	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
KIOLHBIL_01729	2.61e-32	dacA1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOLHBIL_01730	3.01e-274	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIOLHBIL_01731	8.14e-163	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIOLHBIL_01732	1.99e-298	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KIOLHBIL_01733	1.64e-78	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01734	1.69e-31	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOLHBIL_01735	1.07e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KIOLHBIL_01736	3.38e-232	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIOLHBIL_01737	8.63e-275	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIOLHBIL_01738	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
KIOLHBIL_01739	3.36e-27	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
KIOLHBIL_01740	9.93e-90	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
KIOLHBIL_01741	4.53e-302	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01742	5.71e-201	-	-	-	K	ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
KIOLHBIL_01743	2.11e-221	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIOLHBIL_01744	7.86e-49	-	-	-	L	-	-	-	nUDIX hydrolase
KIOLHBIL_01745	2.42e-87	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01746	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KIOLHBIL_01747	8.33e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIOLHBIL_01748	2.08e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIOLHBIL_01749	8.11e-31	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KIOLHBIL_01750	6.95e-12	-	-	-	-	-	-	-	-
KIOLHBIL_01751	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
KIOLHBIL_01752	8.63e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
KIOLHBIL_01753	4.45e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01754	3.24e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOLHBIL_01755	9.51e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
KIOLHBIL_01756	9.09e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIOLHBIL_01757	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOLHBIL_01758	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KIOLHBIL_01759	5.47e-66	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
KIOLHBIL_01760	1.23e-27	ydgJ	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	inositol 2-dehydrogenase activity
KIOLHBIL_01761	6.03e-35	-	-	-	S	-	-	-	oxidoreductase
KIOLHBIL_01762	3.6e-64	-	-	-	S	-	-	-	oxidoreductase
KIOLHBIL_01763	6.61e-296	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
KIOLHBIL_01764	2.42e-81	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
KIOLHBIL_01765	1.51e-40	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
KIOLHBIL_01766	9.86e-38	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
KIOLHBIL_01769	2.04e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
KIOLHBIL_01772	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KIOLHBIL_01773	4.29e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOLHBIL_01774	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOLHBIL_01775	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOLHBIL_01776	1.22e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KIOLHBIL_01777	5.48e-21	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
KIOLHBIL_01778	5.22e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
KIOLHBIL_01779	1.8e-226	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
KIOLHBIL_01780	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KIOLHBIL_01781	2.75e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KIOLHBIL_01782	5.14e-287	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIOLHBIL_01783	2.97e-30	-	-	-	-	-	-	-	-
KIOLHBIL_01784	7.02e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIOLHBIL_01785	3.63e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIOLHBIL_01786	1.28e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
KIOLHBIL_01787	4.15e-296	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KIOLHBIL_01788	3.81e-35	-	-	-	K	-	-	-	hmm pf08876
KIOLHBIL_01789	1.01e-151	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
KIOLHBIL_01790	3.47e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
KIOLHBIL_01791	1.93e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
KIOLHBIL_01792	5.58e-191	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KIOLHBIL_01793	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIOLHBIL_01794	5.47e-29	-	-	-	-	-	-	-	-
KIOLHBIL_01795	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOLHBIL_01796	2.09e-244	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOLHBIL_01797	3.5e-84	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
KIOLHBIL_01799	7.33e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIOLHBIL_01800	2.98e-41	-	-	-	-	-	-	-	-
KIOLHBIL_01801	1.23e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
KIOLHBIL_01802	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIOLHBIL_01803	5.33e-243	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KIOLHBIL_01804	6.83e-228	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
KIOLHBIL_01805	6.27e-220	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KIOLHBIL_01806	3.12e-193	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
KIOLHBIL_01807	2.47e-131	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
KIOLHBIL_01808	1.9e-316	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIOLHBIL_01809	7.72e-57	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
KIOLHBIL_01810	1.29e-24	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	alanine dehydrogenase activity
KIOLHBIL_01811	6.12e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOLHBIL_01812	5.02e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOLHBIL_01813	1.79e-146	-	-	-	S	-	-	-	VIT family
KIOLHBIL_01814	1.01e-180	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOLHBIL_01816	3.94e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
KIOLHBIL_01817	3.93e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
KIOLHBIL_01818	1.79e-157	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOLHBIL_01819	8.21e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOLHBIL_01820	7.53e-247	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KIOLHBIL_01821	4.85e-169	rr02	-	-	KT	-	-	-	response regulator
KIOLHBIL_01822	7.1e-292	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
KIOLHBIL_01823	5.45e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIOLHBIL_01824	4.81e-252	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIOLHBIL_01825	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_01826	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_01828	2.46e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KIOLHBIL_01829	3.14e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIOLHBIL_01830	1.21e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
KIOLHBIL_01831	5.02e-50	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
KIOLHBIL_01832	1.59e-52	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
KIOLHBIL_01833	1.09e-48	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIOLHBIL_01834	8.96e-173	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
KIOLHBIL_01835	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
KIOLHBIL_01836	8.84e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
KIOLHBIL_01837	1.32e-218	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KIOLHBIL_01838	2.25e-285	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
KIOLHBIL_01839	6.68e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIOLHBIL_01840	2.96e-209	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KIOLHBIL_01841	5.69e-100	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIOLHBIL_01842	3.2e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
KIOLHBIL_01846	4.31e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIOLHBIL_01847	1.71e-52	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_01848	1.93e-43	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS glucose transporter subunit IIA
KIOLHBIL_01849	6.26e-65	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_01850	8.26e-91	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_01851	1.31e-28	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOLHBIL_01853	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
KIOLHBIL_01854	1.42e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
KIOLHBIL_01855	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KIOLHBIL_01856	2.48e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KIOLHBIL_01858	2.2e-195	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
KIOLHBIL_01860	1.06e-55	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
KIOLHBIL_01861	7.25e-85	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
KIOLHBIL_01864	2.59e-172	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOLHBIL_01865	8.41e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
KIOLHBIL_01866	4.76e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIOLHBIL_01867	6.41e-25	XK27_00735	-	-	-	-	-	-	-
KIOLHBIL_01868	7.15e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01869	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIOLHBIL_01870	1.27e-39	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
KIOLHBIL_01871	2.32e-72	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOLHBIL_01873	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOLHBIL_01874	2.15e-109	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
KIOLHBIL_01875	6.76e-185	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOLHBIL_01876	9.25e-177	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
KIOLHBIL_01877	6.74e-268	arcT	-	-	E	-	-	-	Aminotransferase
KIOLHBIL_01878	4.07e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOLHBIL_01879	1.9e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KIOLHBIL_01880	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KIOLHBIL_01881	3.03e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KIOLHBIL_01882	4.86e-74	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
KIOLHBIL_01883	1.47e-215	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
KIOLHBIL_01884	1.48e-198	-	-	-	-	-	-	-	-
KIOLHBIL_01885	3.16e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KIOLHBIL_01886	5.65e-160	-	-	-	S	-	-	-	Glycosyl transferase family 2
KIOLHBIL_01887	2.21e-63	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
KIOLHBIL_01888	7.54e-135	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
KIOLHBIL_01889	1.65e-242	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
KIOLHBIL_01890	3.9e-153	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KIOLHBIL_01891	1.89e-181	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KIOLHBIL_01892	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KIOLHBIL_01893	1.05e-276	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
KIOLHBIL_01894	4.06e-222	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
KIOLHBIL_01895	1.71e-34	-	-	-	S	-	-	-	Glucosyl transferase GtrII
KIOLHBIL_01896	2.75e-220	-	-	-	S	-	-	-	Glucosyl transferase GtrII
KIOLHBIL_01897	1.25e-283	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
KIOLHBIL_01898	2.28e-221	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KIOLHBIL_01899	6.03e-179	-	-	-	GM	ko:K01992,ko:K09690,ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
KIOLHBIL_01900	3.59e-283	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KIOLHBIL_01901	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
KIOLHBIL_01902	6.56e-154	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
KIOLHBIL_01903	4.49e-167	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
KIOLHBIL_01904	5.23e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIOLHBIL_01905	1.77e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KIOLHBIL_01906	4.54e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
KIOLHBIL_01907	1.2e-225	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOLHBIL_01908	5.5e-134	yjbK	-	-	S	-	-	-	Adenylate cyclase
KIOLHBIL_01909	5.42e-155	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
KIOLHBIL_01910	1.1e-193	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIOLHBIL_01911	1.32e-220	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KIOLHBIL_01912	1.15e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KIOLHBIL_01913	2.92e-112	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01914	2.48e-39	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_01915	4.37e-137	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
KIOLHBIL_01916	1.39e-276	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
KIOLHBIL_01917	3.08e-29	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
KIOLHBIL_01918	1.1e-105	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOLHBIL_01919	1.02e-139	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
KIOLHBIL_01920	1.23e-160	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOLHBIL_01921	3.45e-83	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
KIOLHBIL_01922	1.04e-182	-	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOLHBIL_01923	5.25e-193	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOLHBIL_01924	1.89e-310	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KIOLHBIL_01925	8.75e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KIOLHBIL_01926	2.77e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
KIOLHBIL_01927	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KIOLHBIL_01928	7.36e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIOLHBIL_01929	1.1e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIOLHBIL_01930	7.75e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KIOLHBIL_01931	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KIOLHBIL_01932	1.09e-154	yvqF	-	-	KT	ko:K11622	ko02020,map02020	ko00000,ko00001	membrane
KIOLHBIL_01933	3.22e-224	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOLHBIL_01934	8.07e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIOLHBIL_01937	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIOLHBIL_01938	4.67e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KIOLHBIL_01939	1.51e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KIOLHBIL_01940	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KIOLHBIL_01941	7.88e-108	-	-	-	L	-	-	-	Transposase
KIOLHBIL_01942	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
KIOLHBIL_01943	8.81e-39	-	-	-	V	ko:K18996,ko:K19171	-	ko00000,ko02048,ko03032	(ABC) transporter
KIOLHBIL_01944	1.48e-124	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_01945	3.16e-24	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
KIOLHBIL_01946	8.2e-50	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
KIOLHBIL_01947	9.12e-174	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	translation initiation factor activity
KIOLHBIL_01948	1.55e-39	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	translation initiation factor activity
KIOLHBIL_01949	2.78e-33	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOLHBIL_01950	1.7e-13	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOLHBIL_01951	8.1e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOLHBIL_01952	6.39e-280	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KIOLHBIL_01953	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
KIOLHBIL_01954	2.99e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOLHBIL_01955	3.41e-257	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KIOLHBIL_01956	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
KIOLHBIL_01957	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
KIOLHBIL_01958	4.41e-80	-	-	-	-	-	-	-	-
KIOLHBIL_01959	2.36e-35	-	-	-	-	-	-	-	-
KIOLHBIL_01960	1.78e-59	-	-	-	-	-	-	-	-
KIOLHBIL_01961	1.68e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIOLHBIL_01962	1.38e-144	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
KIOLHBIL_01963	5.66e-191	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOLHBIL_01964	2.28e-140	mur1	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	mannosyl-glycoprotein
KIOLHBIL_01965	3.22e-71	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
KIOLHBIL_01966	1.48e-296	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
KIOLHBIL_01967	1.03e-205	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIOLHBIL_01968	2.84e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KIOLHBIL_01969	8.56e-179	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
KIOLHBIL_01970	6.71e-208	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
KIOLHBIL_01971	5.91e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIOLHBIL_01972	6.58e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KIOLHBIL_01973	7.86e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIOLHBIL_01974	6.45e-297	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KIOLHBIL_01975	8.85e-97	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KIOLHBIL_01976	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIOLHBIL_01977	9.48e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIOLHBIL_01978	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIOLHBIL_01979	3.66e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOLHBIL_01980	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase F(0) sector subunit b
KIOLHBIL_01981	4.44e-160	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KIOLHBIL_01982	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOLHBIL_01983	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIOLHBIL_01984	6.22e-122	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIOLHBIL_01985	2.62e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOLHBIL_01987	1.65e-189	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
KIOLHBIL_01988	5.25e-198	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KIOLHBIL_01989	5.13e-304	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KIOLHBIL_01990	3.25e-68	icaB	-	-	G	-	-	-	deacetylase
KIOLHBIL_01991	9.71e-108	icaB	-	-	G	-	-	-	deacetylase
KIOLHBIL_01992	6.48e-267	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
KIOLHBIL_01993	7.33e-164	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KIOLHBIL_01994	4.21e-285	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIOLHBIL_01995	4.75e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIOLHBIL_01996	1.73e-291	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
KIOLHBIL_01997	3.29e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KIOLHBIL_01998	3.86e-64	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
KIOLHBIL_01999	2.46e-86	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
KIOLHBIL_02000	4.4e-227	-	-	-	M	-	-	-	GBS Bsp-like repeat
KIOLHBIL_02001	2.28e-29	-	-	-	M	-	-	-	GBS Bsp-like repeat
KIOLHBIL_02002	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIOLHBIL_02003	9.95e-225	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
KIOLHBIL_02004	1.33e-161	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
KIOLHBIL_02005	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KIOLHBIL_02006	6.68e-238	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOLHBIL_02007	9.23e-214	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
KIOLHBIL_02008	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIOLHBIL_02013	4.56e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KIOLHBIL_02014	1.15e-84	sip	-	-	M	-	-	-	LysM domain protein
KIOLHBIL_02016	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_02017	7.62e-191	usp	3.5.1.104, 3.5.1.28	CBM50	S	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133	ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	pathogenesis
KIOLHBIL_02018	3.3e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KIOLHBIL_02019	1.67e-206	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
KIOLHBIL_02020	3.91e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KIOLHBIL_02021	1.38e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KIOLHBIL_02022	7.56e-157	sptS	-	-	T	-	-	-	Histidine kinase
KIOLHBIL_02023	2.65e-57	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KIOLHBIL_02024	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_02025	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_02026	1.79e-100	-	-	-	K	-	-	-	DNA-binding transcription factor activity
KIOLHBIL_02027	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KIOLHBIL_02028	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KIOLHBIL_02029	1.26e-109	nadR	-	-	H	-	-	-	adenylyltransferase
KIOLHBIL_02030	2.62e-101	nadR	-	-	H	-	-	-	adenylyltransferase
KIOLHBIL_02031	1.24e-178	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
KIOLHBIL_02032	1.12e-27	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KIOLHBIL_02033	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
KIOLHBIL_02034	5.56e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KIOLHBIL_02035	3.67e-178	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KIOLHBIL_02036	1.19e-96	-	-	-	S	-	-	-	EDD domain protein, DegV family
KIOLHBIL_02037	1.56e-77	-	-	-	S	-	-	-	EDD domain protein, DegV family
KIOLHBIL_02038	2.74e-84	WQ51_03320	-	-	S	-	-	-	cog cog4835
KIOLHBIL_02039	5.63e-110	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIOLHBIL_02040	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KIOLHBIL_02041	1.64e-63	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KIOLHBIL_02042	1.13e-37	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOLHBIL_02043	1.71e-40	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOLHBIL_02044	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KIOLHBIL_02045	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KIOLHBIL_02046	1.66e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIOLHBIL_02047	1.8e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KIOLHBIL_02048	0.000623	-	-	-	-	-	-	-	-
KIOLHBIL_02049	2.66e-310	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOLHBIL_02050	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIOLHBIL_02051	1e-294	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOLHBIL_02052	1.45e-94	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOLHBIL_02053	7.54e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KIOLHBIL_02054	3.75e-163	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
KIOLHBIL_02055	1.02e-109	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOLHBIL_02056	2.58e-289	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay