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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MIICFEMK_00001	2.01e-204	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
MIICFEMK_00002	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIICFEMK_00003	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MIICFEMK_00004	2.77e-290	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MIICFEMK_00005	2.32e-233	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00006	2.51e-56	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
MIICFEMK_00007	4.86e-297	-	-	-	T	-	-	-	Histidine kinase
MIICFEMK_00008	1.61e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_00009	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
MIICFEMK_00010	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
MIICFEMK_00011	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MIICFEMK_00012	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MIICFEMK_00014	3.68e-68	-	-	-	-	-	-	-	-
MIICFEMK_00015	1.46e-37	-	-	-	-	-	-	-	-
MIICFEMK_00016	8.37e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
MIICFEMK_00018	6.9e-158	-	-	-	-	-	-	-	-
MIICFEMK_00019	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
MIICFEMK_00020	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
MIICFEMK_00021	1.39e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIICFEMK_00022	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIICFEMK_00023	9.85e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
MIICFEMK_00024	1.34e-172	-	-	-	L	-	-	-	Phage integrase family
MIICFEMK_00026	2.42e-278	-	-	-	-	-	-	-	-
MIICFEMK_00027	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MIICFEMK_00028	1.45e-156	-	-	-	L	-	-	-	NUDIX domain
MIICFEMK_00029	5.39e-221	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
MIICFEMK_00030	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIICFEMK_00031	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
MIICFEMK_00033	3.31e-140	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MIICFEMK_00034	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
MIICFEMK_00035	4.13e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
MIICFEMK_00036	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIICFEMK_00037	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIICFEMK_00038	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MIICFEMK_00039	2.97e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIICFEMK_00040	3.14e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MIICFEMK_00041	1.15e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00042	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MIICFEMK_00043	2.56e-108	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIICFEMK_00044	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
MIICFEMK_00045	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIICFEMK_00046	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
MIICFEMK_00047	1.69e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIICFEMK_00048	4.55e-93	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
MIICFEMK_00049	4.46e-166	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
MIICFEMK_00050	2.33e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
MIICFEMK_00051	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MIICFEMK_00052	0.0	-	-	-	-	-	-	-	-
MIICFEMK_00053	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
MIICFEMK_00054	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIICFEMK_00055	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MIICFEMK_00056	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MIICFEMK_00057	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIICFEMK_00058	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIICFEMK_00059	2.77e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MIICFEMK_00060	1.12e-140	-	-	-	-	-	-	-	-
MIICFEMK_00063	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIICFEMK_00064	7.02e-94	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
MIICFEMK_00065	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MIICFEMK_00066	1.26e-125	-	-	-	-	-	-	-	-
MIICFEMK_00068	9.79e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MIICFEMK_00069	1.26e-137	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
MIICFEMK_00070	1.59e-130	-	-	-	D	-	-	-	Septum formation initiator
MIICFEMK_00071	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIICFEMK_00072	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
MIICFEMK_00073	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
MIICFEMK_00074	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIICFEMK_00075	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIICFEMK_00076	9.1e-127	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MIICFEMK_00077	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MIICFEMK_00078	2.42e-194	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MIICFEMK_00079	1.21e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
MIICFEMK_00080	5.21e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIICFEMK_00082	4.13e-275	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MIICFEMK_00083	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIICFEMK_00084	1.18e-262	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIICFEMK_00085	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
MIICFEMK_00086	2.68e-292	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MIICFEMK_00087	3.96e-253	-	-	-	-	-	-	-	-
MIICFEMK_00088	3.29e-192	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00089	3.07e-244	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
MIICFEMK_00090	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
MIICFEMK_00091	5.94e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
MIICFEMK_00092	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIICFEMK_00093	5.21e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
MIICFEMK_00094	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MIICFEMK_00097	1.5e-15	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MIICFEMK_00101	1.9e-98	-	-	-	S	-	-	-	GIY-YIG catalytic domain
MIICFEMK_00102	3.9e-38	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
MIICFEMK_00103	2.69e-137	-	-	-	L	-	-	-	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIICFEMK_00104	7.24e-106	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIICFEMK_00105	1.79e-55	-	-	-	-	-	-	-	-
MIICFEMK_00106	3.02e-90	casA	-	-	L	ko:K19123	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasA
MIICFEMK_00107	3.28e-89	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MIICFEMK_00109	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
MIICFEMK_00110	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIICFEMK_00112	1.19e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_00113	3.58e-239	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIICFEMK_00114	9.87e-263	-	-	-	H	-	-	-	Adenine-specific methyltransferase EcoRI
MIICFEMK_00116	1.09e-05	-	-	-	L	-	-	-	Domain of unknown function (DUF927)
MIICFEMK_00118	2.81e-247	-	-	-	L	-	-	-	Phage integrase family
MIICFEMK_00123	3.28e-10	-	-	-	-	-	-	-	-
MIICFEMK_00124	3.72e-315	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIICFEMK_00125	1.43e-203	-	-	-	S	-	-	-	Protein conserved in bacteria
MIICFEMK_00126	2.75e-268	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIICFEMK_00127	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIICFEMK_00128	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MIICFEMK_00129	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIICFEMK_00130	2.36e-92	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MIICFEMK_00131	3.49e-175	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00132	5.59e-269	-	-	-	E	-	-	-	Aminotransferase class I and II
MIICFEMK_00133	5.64e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIICFEMK_00134	2.4e-136	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIICFEMK_00135	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_00136	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIICFEMK_00138	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
MIICFEMK_00139	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
MIICFEMK_00140	2.49e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MIICFEMK_00141	3.8e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00142	2.97e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00143	2.93e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MIICFEMK_00144	2.08e-180	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
MIICFEMK_00145	1.79e-117	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MIICFEMK_00146	8.44e-97	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_00147	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIICFEMK_00148	4.48e-316	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MIICFEMK_00149	2.14e-301	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
MIICFEMK_00153	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MIICFEMK_00154	2.42e-237	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
MIICFEMK_00155	1.24e-259	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
MIICFEMK_00156	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MIICFEMK_00157	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIICFEMK_00158	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
MIICFEMK_00159	7.36e-227	-	-	-	-	-	-	-	-
MIICFEMK_00160	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
MIICFEMK_00161	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIICFEMK_00162	1.49e-58	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MIICFEMK_00163	7.36e-106	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MIICFEMK_00164	6.04e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIICFEMK_00165	7.07e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MIICFEMK_00166	8.98e-226	-	-	-	S	-	-	-	Protein of unknown function DUF58
MIICFEMK_00167	1.78e-121	-	-	-	-	-	-	-	-
MIICFEMK_00168	1.53e-244	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MIICFEMK_00169	2.85e-198	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MIICFEMK_00170	9.23e-117	-	-	-	-	-	-	-	-
MIICFEMK_00172	0.0	-	-	-	S	-	-	-	PGAP1-like protein
MIICFEMK_00173	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
MIICFEMK_00174	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
MIICFEMK_00175	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
MIICFEMK_00176	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MIICFEMK_00177	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MIICFEMK_00178	3.75e-207	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MIICFEMK_00179	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
MIICFEMK_00180	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
MIICFEMK_00181	5.22e-176	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MIICFEMK_00182	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIICFEMK_00183	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MIICFEMK_00184	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIICFEMK_00185	4.54e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIICFEMK_00186	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIICFEMK_00187	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
MIICFEMK_00188	2.59e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
MIICFEMK_00190	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIICFEMK_00191	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MIICFEMK_00192	4.91e-144	-	-	-	-	-	-	-	-
MIICFEMK_00193	1.59e-314	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIICFEMK_00194	5.36e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
MIICFEMK_00195	2.66e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
MIICFEMK_00196	2.02e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MIICFEMK_00197	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MIICFEMK_00198	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIICFEMK_00199	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIICFEMK_00200	3.06e-211	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MIICFEMK_00201	3.94e-225	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00202	4.74e-236	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MIICFEMK_00203	2.67e-56	-	-	-	-	-	-	-	-
MIICFEMK_00204	2.1e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MIICFEMK_00205	7.12e-254	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MIICFEMK_00206	1.57e-110	-	-	-	-	-	-	-	-
MIICFEMK_00207	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MIICFEMK_00208	8.76e-299	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
MIICFEMK_00209	1.36e-210	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
MIICFEMK_00210	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIICFEMK_00211	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIICFEMK_00212	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
MIICFEMK_00213	6.08e-145	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIICFEMK_00214	5.87e-194	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIICFEMK_00215	7.59e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MIICFEMK_00216	6.57e-226	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
MIICFEMK_00217	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIICFEMK_00218	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MIICFEMK_00219	3.07e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIICFEMK_00220	4.36e-09	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
MIICFEMK_00221	9.85e-12	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
MIICFEMK_00222	3.41e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
MIICFEMK_00223	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIICFEMK_00224	7.08e-118	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIICFEMK_00226	3.63e-228	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIICFEMK_00227	6.49e-249	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MIICFEMK_00228	3.35e-84	-	-	-	-	-	-	-	-
MIICFEMK_00229	9.94e-149	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MIICFEMK_00230	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIICFEMK_00231	5.13e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
MIICFEMK_00232	4.43e-294	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
MIICFEMK_00233	3.1e-310	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
MIICFEMK_00234	2.31e-174	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MIICFEMK_00235	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MIICFEMK_00236	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MIICFEMK_00238	3.73e-126	-	-	-	F	-	-	-	NUDIX domain
MIICFEMK_00239	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MIICFEMK_00240	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIICFEMK_00241	2.16e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00242	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00243	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIICFEMK_00244	6.26e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MIICFEMK_00245	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIICFEMK_00246	5.86e-276	-	-	-	GK	-	-	-	ROK family
MIICFEMK_00247	3.42e-169	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
MIICFEMK_00248	5.33e-286	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIICFEMK_00249	1.17e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MIICFEMK_00250	6.45e-302	-	-	-	G	-	-	-	Major Facilitator Superfamily
MIICFEMK_00251	2.9e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIICFEMK_00254	3.75e-228	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
MIICFEMK_00255	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MIICFEMK_00256	7.4e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIICFEMK_00257	4.49e-297	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
MIICFEMK_00258	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIICFEMK_00259	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIICFEMK_00260	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIICFEMK_00261	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIICFEMK_00262	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
MIICFEMK_00263	1.96e-97	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIICFEMK_00264	3.08e-246	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIICFEMK_00265	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MIICFEMK_00266	0.0	-	-	-	L	-	-	-	DNA helicase
MIICFEMK_00267	9.66e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MIICFEMK_00268	3.1e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIICFEMK_00269	2.76e-65	-	-	-	M	-	-	-	Lysin motif
MIICFEMK_00270	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIICFEMK_00271	4.73e-214	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIICFEMK_00272	1.96e-226	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MIICFEMK_00273	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIICFEMK_00274	1.32e-221	-	-	-	-	-	-	-	-
MIICFEMK_00275	2.51e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MIICFEMK_00276	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
MIICFEMK_00277	1.03e-242	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MIICFEMK_00278	2e-75	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
MIICFEMK_00279	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MIICFEMK_00280	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MIICFEMK_00281	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
MIICFEMK_00282	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MIICFEMK_00283	1.35e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIICFEMK_00284	5.28e-151	-	-	-	-	-	-	-	-
MIICFEMK_00285	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MIICFEMK_00286	2.16e-284	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIICFEMK_00287	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIICFEMK_00288	2.68e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
MIICFEMK_00291	1.5e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
MIICFEMK_00292	2.11e-221	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
MIICFEMK_00293	5.5e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
MIICFEMK_00294	2.5e-258	-	-	-	K	-	-	-	WYL domain
MIICFEMK_00296	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MIICFEMK_00297	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
MIICFEMK_00298	1.07e-163	-	-	-	S	-	-	-	zinc-ribbon domain
MIICFEMK_00299	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
MIICFEMK_00300	4.54e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MIICFEMK_00301	1.2e-19	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MIICFEMK_00302	1.65e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MIICFEMK_00303	1.03e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIICFEMK_00304	4.82e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MIICFEMK_00305	0.0	-	-	-	I	-	-	-	acetylesterase activity
MIICFEMK_00306	3.99e-298	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIICFEMK_00307	2.16e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIICFEMK_00308	7.14e-316	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MIICFEMK_00310	3.79e-16	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_00311	9.38e-13	-	-	-	-	-	-	-	-
MIICFEMK_00312	1.07e-115	-	-	-	-	-	-	-	-
MIICFEMK_00314	1.84e-186	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
MIICFEMK_00315	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MIICFEMK_00316	1.35e-279	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
MIICFEMK_00317	4.29e-203	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
MIICFEMK_00318	3.39e-298	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
MIICFEMK_00319	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIICFEMK_00320	2.62e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MIICFEMK_00321	2.43e-80	-	-	-	-	-	-	-	-
MIICFEMK_00323	2.68e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MIICFEMK_00324	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIICFEMK_00325	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
MIICFEMK_00326	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MIICFEMK_00327	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIICFEMK_00328	8.03e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIICFEMK_00329	4.69e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIICFEMK_00330	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
MIICFEMK_00331	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
MIICFEMK_00332	1.5e-203	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIICFEMK_00333	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIICFEMK_00334	1.62e-110	-	-	-	-	-	-	-	-
MIICFEMK_00335	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
MIICFEMK_00336	1.47e-210	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MIICFEMK_00337	2.08e-79	-	-	-	S	-	-	-	Thiamine-binding protein
MIICFEMK_00338	3.24e-247	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_00339	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
MIICFEMK_00340	1.18e-192	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MIICFEMK_00341	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MIICFEMK_00342	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MIICFEMK_00343	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MIICFEMK_00344	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
MIICFEMK_00345	3.62e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
MIICFEMK_00346	2.91e-148	-	-	-	S	-	-	-	Vitamin K epoxide reductase
MIICFEMK_00347	7.32e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MIICFEMK_00348	3.31e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MIICFEMK_00349	4.37e-218	-	-	-	S	-	-	-	Patatin-like phospholipase
MIICFEMK_00350	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MIICFEMK_00351	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_00352	4.46e-118	-	-	-	K	-	-	-	MarR family
MIICFEMK_00353	2.93e-68	-	-	-	M	-	-	-	Parallel beta-helix repeats
MIICFEMK_00358	1.9e-05	-	-	-	M	-	-	-	Parallel beta-helix repeats
MIICFEMK_00359	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
MIICFEMK_00360	1.59e-212	-	-	-	-	-	-	-	-
MIICFEMK_00361	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
MIICFEMK_00363	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIICFEMK_00364	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MIICFEMK_00365	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIICFEMK_00366	2.08e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIICFEMK_00367	1.11e-260	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MIICFEMK_00370	2.62e-231	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MIICFEMK_00371	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
MIICFEMK_00372	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MIICFEMK_00373	2.78e-170	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
MIICFEMK_00374	2.21e-47	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MIICFEMK_00375	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
MIICFEMK_00376	2.43e-129	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MIICFEMK_00377	0.0	-	-	-	S	-	-	-	zinc finger
MIICFEMK_00378	6.43e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIICFEMK_00379	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIICFEMK_00380	0.0	vpr	-	-	O	-	-	-	Subtilase family
MIICFEMK_00381	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
MIICFEMK_00382	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIICFEMK_00383	5.72e-207	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIICFEMK_00384	1.16e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIICFEMK_00385	1.39e-74	-	-	-	L	-	-	-	Transposase
MIICFEMK_00386	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MIICFEMK_00387	1.03e-55	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MIICFEMK_00388	6.14e-87	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIICFEMK_00389	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
MIICFEMK_00390	1.71e-204	-	-	-	K	-	-	-	-acetyltransferase
MIICFEMK_00391	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
MIICFEMK_00392	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MIICFEMK_00393	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIICFEMK_00394	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
MIICFEMK_00395	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MIICFEMK_00396	1.92e-300	-	-	-	S	-	-	-	Protein of unknown function DUF58
MIICFEMK_00397	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MIICFEMK_00398	1.16e-211	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MIICFEMK_00399	1.71e-100	-	-	-	B	-	-	-	Belongs to the OprB family
MIICFEMK_00400	6.53e-125	-	-	-	T	-	-	-	Forkhead associated domain
MIICFEMK_00401	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIICFEMK_00402	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIICFEMK_00403	6.04e-127	-	-	-	-	-	-	-	-
MIICFEMK_00404	3.15e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
MIICFEMK_00405	3.52e-37	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
MIICFEMK_00406	7.7e-77	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
MIICFEMK_00407	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIICFEMK_00409	3.98e-94	-	-	-	-	-	-	-	-
MIICFEMK_00410	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MIICFEMK_00411	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MIICFEMK_00412	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MIICFEMK_00413	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
MIICFEMK_00414	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
MIICFEMK_00415	1.2e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MIICFEMK_00416	4.9e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MIICFEMK_00417	1.5e-277	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MIICFEMK_00418	0.0	pon1	-	-	M	-	-	-	Transglycosylase
MIICFEMK_00419	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MIICFEMK_00420	8.97e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MIICFEMK_00421	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIICFEMK_00422	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
MIICFEMK_00423	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
MIICFEMK_00424	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MIICFEMK_00425	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MIICFEMK_00427	1.03e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MIICFEMK_00428	8.16e-154	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
MIICFEMK_00429	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
MIICFEMK_00430	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
MIICFEMK_00431	0.0	-	-	-	-	-	-	-	-
MIICFEMK_00432	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MIICFEMK_00433	1.25e-298	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MIICFEMK_00434	2.77e-158	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
MIICFEMK_00435	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MIICFEMK_00436	2.78e-259	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIICFEMK_00437	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MIICFEMK_00440	2.33e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIICFEMK_00441	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIICFEMK_00442	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIICFEMK_00444	7.62e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MIICFEMK_00445	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIICFEMK_00446	6.96e-200	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MIICFEMK_00447	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIICFEMK_00448	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
MIICFEMK_00449	6.29e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MIICFEMK_00450	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MIICFEMK_00451	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MIICFEMK_00452	8.57e-222	-	-	-	K	-	-	-	Putative sugar-binding domain
MIICFEMK_00453	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00454	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00455	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
MIICFEMK_00456	2.62e-157	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MIICFEMK_00458	6.19e-263	-	-	-	-	-	-	-	-
MIICFEMK_00460	3.89e-27	-	-	-	-	-	-	-	-
MIICFEMK_00461	4.28e-228	-	-	-	-	-	-	-	-
MIICFEMK_00462	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MIICFEMK_00465	3.96e-228	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
MIICFEMK_00466	1.14e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIICFEMK_00467	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIICFEMK_00468	1.65e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIICFEMK_00471	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MIICFEMK_00472	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MIICFEMK_00473	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIICFEMK_00474	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MIICFEMK_00475	3.08e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MIICFEMK_00476	4.28e-184	-	-	-	-	-	-	-	-
MIICFEMK_00477	2.77e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIICFEMK_00478	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
MIICFEMK_00479	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
MIICFEMK_00480	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
MIICFEMK_00481	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIICFEMK_00482	2.09e-212	-	-	-	P	-	-	-	Cation efflux family
MIICFEMK_00483	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIICFEMK_00484	1.84e-280	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MIICFEMK_00485	1.36e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
MIICFEMK_00486	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
MIICFEMK_00487	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MIICFEMK_00488	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MIICFEMK_00489	2.27e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIICFEMK_00490	1.37e-223	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MIICFEMK_00491	1.25e-106	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
MIICFEMK_00492	1.65e-140	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MIICFEMK_00493	4.41e-155	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
MIICFEMK_00494	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
MIICFEMK_00495	0.0	-	-	-	-	-	-	-	-
MIICFEMK_00498	6.08e-279	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MIICFEMK_00499	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
MIICFEMK_00500	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MIICFEMK_00501	2.69e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MIICFEMK_00503	1.23e-308	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MIICFEMK_00504	7.96e-169	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MIICFEMK_00505	1.35e-12	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
MIICFEMK_00506	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
MIICFEMK_00507	3.43e-300	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MIICFEMK_00508	1.27e-161	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
MIICFEMK_00513	2.96e-43	-	-	-	-	-	-	-	-
MIICFEMK_00514	0.00013	-	-	-	TV	ko:K05792	-	ko00000	HNH endonuclease
MIICFEMK_00515	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIICFEMK_00516	2.76e-55	-	-	-	K	-	-	-	Transcriptional regulator
MIICFEMK_00519	7.27e-25	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
MIICFEMK_00520	1.67e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
MIICFEMK_00521	1.37e-306	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_00522	1.51e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIICFEMK_00523	1.04e-169	-	-	-	M	-	-	-	Mechanosensitive ion channel
MIICFEMK_00524	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MIICFEMK_00526	2.84e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MIICFEMK_00527	2.48e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
MIICFEMK_00528	5.35e-270	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIICFEMK_00529	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
MIICFEMK_00530	0.0	-	-	-	M	-	-	-	domain protein
MIICFEMK_00531	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
MIICFEMK_00532	2.58e-190	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIICFEMK_00533	5.99e-237	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIICFEMK_00534	3.2e-176	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
MIICFEMK_00535	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MIICFEMK_00537	5.3e-97	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
MIICFEMK_00538	9.21e-52	-	-	-	S	-	-	-	Parallel beta-helix repeats
MIICFEMK_00541	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MIICFEMK_00542	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIICFEMK_00543	7.91e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MIICFEMK_00544	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MIICFEMK_00545	1.51e-227	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
MIICFEMK_00546	5.79e-167	-	-	-	-	-	-	-	-
MIICFEMK_00547	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIICFEMK_00548	5.34e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIICFEMK_00549	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
MIICFEMK_00550	1.82e-254	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MIICFEMK_00551	4.08e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MIICFEMK_00552	1.61e-226	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MIICFEMK_00553	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MIICFEMK_00554	8.55e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MIICFEMK_00555	2.02e-43	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIICFEMK_00557	7.11e-295	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MIICFEMK_00558	6.1e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIICFEMK_00559	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIICFEMK_00560	1.94e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MIICFEMK_00561	2.2e-274	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIICFEMK_00562	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MIICFEMK_00563	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MIICFEMK_00564	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
MIICFEMK_00565	4.04e-304	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MIICFEMK_00566	9.55e-215	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
MIICFEMK_00567	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
MIICFEMK_00568	2.63e-209	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00569	8.09e-76	-	-	-	-	-	-	-	-
MIICFEMK_00570	2.94e-80	-	-	-	-	-	-	-	-
MIICFEMK_00571	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
MIICFEMK_00572	5.51e-239	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIICFEMK_00573	1.79e-304	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MIICFEMK_00574	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MIICFEMK_00575	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MIICFEMK_00576	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIICFEMK_00577	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MIICFEMK_00578	3.76e-228	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MIICFEMK_00579	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
MIICFEMK_00580	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
MIICFEMK_00582	2.15e-193	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MIICFEMK_00583	9.18e-83	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MIICFEMK_00584	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MIICFEMK_00586	3.33e-153	-	-	-	S	-	-	-	CYTH
MIICFEMK_00587	1.03e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
MIICFEMK_00588	8.35e-232	-	-	-	-	-	-	-	-
MIICFEMK_00589	3.84e-238	-	-	-	-	-	-	-	-
MIICFEMK_00590	7.31e-222	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
MIICFEMK_00591	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIICFEMK_00592	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIICFEMK_00593	1.85e-181	-	-	-	-	-	-	-	-
MIICFEMK_00594	9.78e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIICFEMK_00595	2.74e-288	-	-	-	G	-	-	-	Transmembrane secretion effector
MIICFEMK_00596	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIICFEMK_00597	5.26e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
MIICFEMK_00598	1.37e-248	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MIICFEMK_00600	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_00601	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIICFEMK_00602	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIICFEMK_00603	1.59e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
MIICFEMK_00604	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MIICFEMK_00607	2.56e-83	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MIICFEMK_00608	8.37e-124	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MIICFEMK_00609	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIICFEMK_00611	1.65e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MIICFEMK_00612	2.92e-257	-	-	-	P	-	-	-	NMT1/THI5 like
MIICFEMK_00613	4.99e-179	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00614	1.64e-193	-	-	-	-	-	-	-	-
MIICFEMK_00615	1.11e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MIICFEMK_00616	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIICFEMK_00617	6.15e-127	-	-	-	S	-	-	-	GtrA-like protein
MIICFEMK_00618	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
MIICFEMK_00619	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
MIICFEMK_00620	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MIICFEMK_00621	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MIICFEMK_00622	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MIICFEMK_00624	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MIICFEMK_00625	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_00626	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MIICFEMK_00627	5.18e-243	-	-	-	C	-	-	-	Aldo/keto reductase family
MIICFEMK_00628	1.19e-130	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
MIICFEMK_00629	4.45e-21	-	-	-	-	-	-	-	-
MIICFEMK_00631	0.0	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIICFEMK_00634	8.94e-135	-	-	-	-	-	-	-	-
MIICFEMK_00635	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
MIICFEMK_00636	4.68e-78	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MIICFEMK_00637	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIICFEMK_00638	9.37e-228	-	-	-	V	-	-	-	Abi-like protein
MIICFEMK_00639	3.68e-298	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MIICFEMK_00641	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
MIICFEMK_00642	0.0	-	-	-	-	-	-	-	-
MIICFEMK_00643	2.72e-20	-	-	-	-	-	-	-	-
MIICFEMK_00644	2.79e-118	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
MIICFEMK_00645	1.11e-148	-	-	-	K	-	-	-	WHG domain
MIICFEMK_00646	8.21e-48	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
MIICFEMK_00647	1.29e-170	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
MIICFEMK_00648	1.57e-54	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
MIICFEMK_00649	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIICFEMK_00651	3.25e-307	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIICFEMK_00652	2.86e-72	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
MIICFEMK_00653	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIICFEMK_00654	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MIICFEMK_00655	4.44e-136	-	-	-	L	ko:K07485	-	ko00000	Transposase
MIICFEMK_00656	8.66e-57	-	-	-	O	-	-	-	Glutaredoxin
MIICFEMK_00657	6.76e-193	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
MIICFEMK_00658	8.29e-129	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
MIICFEMK_00659	3.65e-50	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MIICFEMK_00660	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIICFEMK_00661	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIICFEMK_00662	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIICFEMK_00663	6.12e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIICFEMK_00664	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MIICFEMK_00665	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
MIICFEMK_00666	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIICFEMK_00667	9.44e-234	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
MIICFEMK_00668	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIICFEMK_00669	2.51e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIICFEMK_00670	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MIICFEMK_00671	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
MIICFEMK_00672	1.81e-98	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
MIICFEMK_00673	6.11e-252	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_00674	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIICFEMK_00675	8.76e-211	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIICFEMK_00676	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIICFEMK_00677	2.17e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MIICFEMK_00678	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MIICFEMK_00679	1.42e-74	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MIICFEMK_00681	7.82e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MIICFEMK_00682	4.81e-84	-	-	-	-	-	-	-	-
MIICFEMK_00683	4.37e-80	-	-	-	-	-	-	-	-
MIICFEMK_00685	3.76e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
MIICFEMK_00686	1.23e-55	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MIICFEMK_00687	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIICFEMK_00689	2.55e-218	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MIICFEMK_00690	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MIICFEMK_00691	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MIICFEMK_00692	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
MIICFEMK_00693	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIICFEMK_00695	4.51e-110	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
MIICFEMK_00696	1.08e-189	-	-	-	I	-	-	-	Serine aminopeptidase, S33
MIICFEMK_00697	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
MIICFEMK_00698	2.14e-57	-	-	-	D	-	-	-	DivIVA domain protein
MIICFEMK_00699	1.3e-116	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MIICFEMK_00700	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
MIICFEMK_00702	1.17e-250	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIICFEMK_00704	4.72e-147	-	-	-	-	-	-	-	-
MIICFEMK_00705	2.55e-213	-	-	-	EG	-	-	-	EamA-like transporter family
MIICFEMK_00706	1.7e-263	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
MIICFEMK_00707	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIICFEMK_00708	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MIICFEMK_00709	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MIICFEMK_00710	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
MIICFEMK_00711	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MIICFEMK_00712	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MIICFEMK_00713	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MIICFEMK_00714	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MIICFEMK_00715	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIICFEMK_00716	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MIICFEMK_00717	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
MIICFEMK_00718	5.65e-296	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIICFEMK_00719	1.18e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIICFEMK_00720	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
MIICFEMK_00721	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
MIICFEMK_00722	1.47e-155	-	-	-	L	-	-	-	HTH-like domain
MIICFEMK_00723	4.85e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MIICFEMK_00724	7.68e-47	-	-	-	-	-	-	-	-
MIICFEMK_00725	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIICFEMK_00726	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
MIICFEMK_00727	2.19e-60	-	-	-	L	ko:K07485	-	ko00000	Transposase
MIICFEMK_00728	1.6e-69	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MIICFEMK_00729	1.21e-57	-	-	-	L	-	-	-	Integrase core domain
MIICFEMK_00730	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MIICFEMK_00731	1.9e-17	-	-	-	-	-	-	-	-
MIICFEMK_00732	4.36e-24	yccF	-	-	S	-	-	-	Inner membrane component domain
MIICFEMK_00733	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MIICFEMK_00734	1.78e-240	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIICFEMK_00735	1.29e-198	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00736	5.39e-181	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
MIICFEMK_00737	3.03e-209	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00738	1.72e-218	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_00739	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MIICFEMK_00740	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIICFEMK_00741	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIICFEMK_00742	3.29e-82	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
MIICFEMK_00743	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIICFEMK_00744	1.79e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MIICFEMK_00745	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
MIICFEMK_00746	1.47e-22	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MIICFEMK_00747	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MIICFEMK_00749	4.81e-56	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIICFEMK_00750	3.34e-225	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIICFEMK_00751	2.95e-142	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
MIICFEMK_00752	1.9e-189	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
MIICFEMK_00753	1.19e-305	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csd1)
MIICFEMK_00754	6.69e-133	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
MIICFEMK_00755	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
MIICFEMK_00756	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIICFEMK_00757	2.38e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MIICFEMK_00758	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
MIICFEMK_00759	1.52e-179	hflK	-	-	O	-	-	-	prohibitin homologues
MIICFEMK_00760	8.24e-307	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIICFEMK_00761	5.45e-299	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIICFEMK_00762	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MIICFEMK_00763	1.17e-286	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MIICFEMK_00764	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00765	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MIICFEMK_00766	2.11e-119	-	-	-	K	-	-	-	acetyltransferase
MIICFEMK_00767	2.16e-103	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIICFEMK_00768	2.46e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MIICFEMK_00769	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
MIICFEMK_00770	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MIICFEMK_00771	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MIICFEMK_00772	7.75e-187	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MIICFEMK_00773	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
MIICFEMK_00774	4e-156	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MIICFEMK_00775	5.42e-219	-	-	-	-	-	-	-	-
MIICFEMK_00776	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIICFEMK_00778	0.0	-	-	-	L	-	-	-	PIF1-like helicase
MIICFEMK_00779	7.82e-203	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIICFEMK_00780	1.91e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIICFEMK_00781	4.86e-92	-	-	-	KT	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MIICFEMK_00782	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MIICFEMK_00783	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIICFEMK_00784	2.14e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
MIICFEMK_00785	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
MIICFEMK_00786	8.39e-73	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
MIICFEMK_00787	1.2e-236	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIICFEMK_00788	1.17e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIICFEMK_00789	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MIICFEMK_00791	1.38e-251	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
MIICFEMK_00792	2.74e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
MIICFEMK_00793	4.72e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MIICFEMK_00794	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
MIICFEMK_00795	3.01e-143	-	-	-	-	-	-	-	-
MIICFEMK_00796	8.81e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
MIICFEMK_00797	9.28e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
MIICFEMK_00798	1.68e-190	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MIICFEMK_00799	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
MIICFEMK_00800	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
MIICFEMK_00802	3.65e-65	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIICFEMK_00803	7.41e-191	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MIICFEMK_00805	9.5e-39	-	-	-	L	-	-	-	Transposase
MIICFEMK_00806	1.5e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_00807	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
MIICFEMK_00808	7.9e-48	-	-	-	C	-	-	-	Aldo/keto reductase family
MIICFEMK_00809	1.54e-100	-	-	-	EGP	-	-	-	Major facilitator superfamily
MIICFEMK_00810	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIICFEMK_00811	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
MIICFEMK_00812	4.9e-76	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
MIICFEMK_00813	5.09e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MIICFEMK_00814	4.04e-149	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MIICFEMK_00816	7.29e-65	-	-	-	S	-	-	-	DUF218 domain
MIICFEMK_00817	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
MIICFEMK_00818	3.7e-149	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIICFEMK_00819	1.76e-161	-	-	-	-	-	-	-	-
MIICFEMK_00820	4.24e-225	-	-	-	M	-	-	-	domain, Protein
MIICFEMK_00821	1.42e-18	-	-	-	M	-	-	-	domain, Protein
MIICFEMK_00822	3.61e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF3791)
MIICFEMK_00823	3.98e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
MIICFEMK_00825	1.51e-87	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MIICFEMK_00826	8.06e-34	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MIICFEMK_00828	3.67e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF4825)
MIICFEMK_00829	2.83e-58	-	-	-	K	-	-	-	response regulator
MIICFEMK_00830	8.74e-62	-	-	-	T	-	-	-	response regulator
MIICFEMK_00831	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
MIICFEMK_00832	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
MIICFEMK_00833	2.66e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
MIICFEMK_00834	2.35e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
MIICFEMK_00835	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIICFEMK_00836	3.91e-211	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIICFEMK_00837	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MIICFEMK_00838	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIICFEMK_00839	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MIICFEMK_00840	2.1e-270	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIICFEMK_00841	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MIICFEMK_00842	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MIICFEMK_00843	2.26e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_00844	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
MIICFEMK_00845	0.0	-	-	-	S	-	-	-	AI-2E family transporter
MIICFEMK_00846	1.89e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MIICFEMK_00847	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MIICFEMK_00850	2.03e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
MIICFEMK_00851	1.14e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIICFEMK_00852	1.16e-196	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIICFEMK_00854	1.17e-21	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
MIICFEMK_00855	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MIICFEMK_00856	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MIICFEMK_00857	5.77e-77	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MIICFEMK_00858	1.23e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MIICFEMK_00859	2.57e-14	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIICFEMK_00860	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MIICFEMK_00861	2.52e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
MIICFEMK_00862	5.06e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_00863	1.23e-60	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MIICFEMK_00864	4.43e-250	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MIICFEMK_00865	9.52e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
MIICFEMK_00866	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
MIICFEMK_00867	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIICFEMK_00868	4.35e-94	-	-	-	O	-	-	-	OsmC-like protein
MIICFEMK_00869	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
MIICFEMK_00870	3.6e-148	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MIICFEMK_00871	1.43e-229	-	-	-	S	-	-	-	CHAP domain
MIICFEMK_00872	1.28e-275	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIICFEMK_00873	4.6e-53	-	-	-	-	-	-	-	-
MIICFEMK_00874	9.24e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIICFEMK_00875	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MIICFEMK_00876	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MIICFEMK_00877	2.89e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MIICFEMK_00878	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MIICFEMK_00880	7.45e-278	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MIICFEMK_00881	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MIICFEMK_00882	9.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
MIICFEMK_00883	9.16e-196	-	-	-	-	-	-	-	-
MIICFEMK_00884	0.0	pspC	-	-	KT	-	-	-	PspC domain
MIICFEMK_00885	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
MIICFEMK_00886	3.32e-163	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_00887	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIICFEMK_00888	8.29e-181	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MIICFEMK_00889	1.77e-238	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
MIICFEMK_00890	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIICFEMK_00891	2.61e-122	-	-	-	-	-	-	-	-
MIICFEMK_00893	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MIICFEMK_00895	2.32e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIICFEMK_00896	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
MIICFEMK_00897	3.25e-273	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MIICFEMK_00898	3.56e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MIICFEMK_00899	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
MIICFEMK_00900	4.73e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
MIICFEMK_00901	4.43e-57	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
MIICFEMK_00903	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MIICFEMK_00904	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIICFEMK_00905	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
MIICFEMK_00906	2.06e-259	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIICFEMK_00907	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIICFEMK_00908	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MIICFEMK_00909	8.06e-141	-	-	-	-	-	-	-	-
MIICFEMK_00910	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIICFEMK_00911	2.08e-303	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
MIICFEMK_00912	2.85e-302	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIICFEMK_00913	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIICFEMK_00914	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIICFEMK_00915	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MIICFEMK_00916	6.58e-227	-	-	-	-	-	-	-	-
MIICFEMK_00917	4.97e-186	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
MIICFEMK_00919	5.51e-199	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
MIICFEMK_00920	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
MIICFEMK_00921	4.08e-221	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIICFEMK_00922	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
MIICFEMK_00923	2.18e-94	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MIICFEMK_00924	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIICFEMK_00925	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIICFEMK_00926	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIICFEMK_00927	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MIICFEMK_00928	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIICFEMK_00929	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIICFEMK_00930	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIICFEMK_00931	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MIICFEMK_00932	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
MIICFEMK_00933	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIICFEMK_00934	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIICFEMK_00935	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIICFEMK_00936	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIICFEMK_00937	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIICFEMK_00938	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIICFEMK_00939	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIICFEMK_00940	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIICFEMK_00941	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIICFEMK_00942	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MIICFEMK_00943	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIICFEMK_00944	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIICFEMK_00945	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIICFEMK_00946	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIICFEMK_00947	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIICFEMK_00948	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIICFEMK_00949	2.7e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MIICFEMK_00950	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIICFEMK_00951	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MIICFEMK_00952	1.33e-122	-	-	-	S	-	-	-	YwiC-like protein
MIICFEMK_00953	1.36e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MIICFEMK_00954	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MIICFEMK_00955	2.49e-297	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MIICFEMK_00956	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MIICFEMK_00957	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MIICFEMK_00958	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIICFEMK_00959	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MIICFEMK_00960	1.7e-154	-	-	-	-	-	-	-	-
MIICFEMK_00961	5.69e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
MIICFEMK_00962	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
MIICFEMK_00964	2.66e-307	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIICFEMK_00965	1.41e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
MIICFEMK_00966	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
MIICFEMK_00967	4.5e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MIICFEMK_00968	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MIICFEMK_00972	6.42e-57	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MIICFEMK_00973	1.49e-171	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MIICFEMK_00974	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIICFEMK_00975	2e-266	-	-	-	-	-	-	-	-
MIICFEMK_00976	4.03e-190	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MIICFEMK_00977	5.69e-154	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MIICFEMK_00978	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
MIICFEMK_00979	2.1e-141	-	-	-	NO	-	-	-	SAF
MIICFEMK_00980	2.87e-56	-	-	-	-	-	-	-	-
MIICFEMK_00981	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
MIICFEMK_00982	0.0	-	-	-	T	-	-	-	Forkhead associated domain
MIICFEMK_00984	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIICFEMK_00985	2.06e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIICFEMK_00986	1.25e-236	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
MIICFEMK_00987	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
MIICFEMK_00989	5.92e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MIICFEMK_00991	7.39e-219	-	-	-	S	-	-	-	Protein conserved in bacteria
MIICFEMK_00992	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIICFEMK_00993	6.61e-234	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MIICFEMK_00994	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MIICFEMK_00995	1.71e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
MIICFEMK_00996	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MIICFEMK_00997	1.56e-312	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MIICFEMK_00998	7.68e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIICFEMK_00999	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIICFEMK_01000	2.63e-142	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MIICFEMK_01001	1.34e-313	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MIICFEMK_01002	3.97e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIICFEMK_01003	9.68e-230	-	-	-	L	-	-	-	Excalibur calcium-binding domain
MIICFEMK_01004	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MIICFEMK_01005	3.81e-124	-	-	-	D	-	-	-	nuclear chromosome segregation
MIICFEMK_01006	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIICFEMK_01007	9.04e-186	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIICFEMK_01008	2.74e-241	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MIICFEMK_01009	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
MIICFEMK_01010	1.45e-125	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MIICFEMK_01011	1.53e-118	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MIICFEMK_01012	6.85e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
MIICFEMK_01013	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MIICFEMK_01014	3.47e-128	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MIICFEMK_01015	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIICFEMK_01016	1.03e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIICFEMK_01017	6.87e-92	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIICFEMK_01018	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MIICFEMK_01019	2.63e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MIICFEMK_01020	2.19e-56	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
MIICFEMK_01021	3.32e-194	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
MIICFEMK_01022	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIICFEMK_01023	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIICFEMK_01024	3.14e-155	-	-	-	-	-	-	-	-
MIICFEMK_01025	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
MIICFEMK_01027	4.39e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MIICFEMK_01028	6.53e-127	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIICFEMK_01029	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
MIICFEMK_01030	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
MIICFEMK_01031	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MIICFEMK_01032	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MIICFEMK_01033	2.25e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MIICFEMK_01034	0.0	-	-	-	-	-	-	-	-
MIICFEMK_01035	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MIICFEMK_01036	1.83e-167	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MIICFEMK_01037	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MIICFEMK_01038	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIICFEMK_01039	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIICFEMK_01040	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIICFEMK_01041	2.81e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIICFEMK_01042	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIICFEMK_01043	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIICFEMK_01045	1.01e-187	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MIICFEMK_01046	2.94e-265	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIICFEMK_01048	2.17e-47	-	-	-	-	-	-	-	-
MIICFEMK_01049	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
MIICFEMK_01050	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MIICFEMK_01051	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIICFEMK_01053	3.89e-132	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MIICFEMK_01054	5.6e-170	-	-	-	-	-	-	-	-
MIICFEMK_01055	7.59e-173	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
MIICFEMK_01056	2e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIICFEMK_01057	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MIICFEMK_01058	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIICFEMK_01059	0.0	-	-	-	S	-	-	-	domain protein
MIICFEMK_01060	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MIICFEMK_01061	5.4e-118	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MIICFEMK_01062	5.02e-298	-	2.6.1.1	-	E	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
MIICFEMK_01063	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIICFEMK_01064	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MIICFEMK_01065	1.32e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
MIICFEMK_01066	1.32e-249	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MIICFEMK_01067	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIICFEMK_01068	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIICFEMK_01069	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIICFEMK_01070	1.28e-106	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MIICFEMK_01071	2.72e-54	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MIICFEMK_01072	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
MIICFEMK_01073	2.47e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIICFEMK_01074	2.93e-297	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
MIICFEMK_01075	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
MIICFEMK_01076	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MIICFEMK_01077	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
MIICFEMK_01078	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
MIICFEMK_01079	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MIICFEMK_01080	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
MIICFEMK_01081	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MIICFEMK_01082	0.0	dinF	-	-	V	-	-	-	MatE
MIICFEMK_01083	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
MIICFEMK_01084	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
MIICFEMK_01085	2.1e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
MIICFEMK_01086	3.69e-278	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIICFEMK_01088	1.17e-172	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIICFEMK_01089	8e-254	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
MIICFEMK_01090	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
MIICFEMK_01091	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MIICFEMK_01092	3.32e-13	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
MIICFEMK_01093	8.22e-25	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MIICFEMK_01094	2.83e-89	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MIICFEMK_01095	2.01e-107	-	-	-	-	-	-	-	-
MIICFEMK_01096	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MIICFEMK_01097	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_01098	2.29e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MIICFEMK_01099	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
MIICFEMK_01100	3.14e-240	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
MIICFEMK_01101	1.44e-257	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
MIICFEMK_01102	4.25e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIICFEMK_01104	1.72e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIICFEMK_01105	7.6e-306	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIICFEMK_01106	2.24e-103	-	-	-	-	-	-	-	-
MIICFEMK_01107	4.47e-46	-	-	-	Q	-	-	-	phosphatase activity
MIICFEMK_01108	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MIICFEMK_01109	2.6e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MIICFEMK_01110	1.2e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MIICFEMK_01111	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIICFEMK_01112	4.98e-90	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MIICFEMK_01113	1.85e-06	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MIICFEMK_01114	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
MIICFEMK_01115	8.08e-103	-	-	-	S	-	-	-	FMN_bind
MIICFEMK_01116	7.76e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_01117	2.51e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIICFEMK_01118	3.23e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MIICFEMK_01119	5.03e-295	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
MIICFEMK_01120	2.37e-146	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
MIICFEMK_01121	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
MIICFEMK_01122	3.52e-32	-	-	-	G	-	-	-	MFS/sugar transport protein
MIICFEMK_01123	4.61e-253	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MIICFEMK_01124	6.49e-77	-	-	-	S	-	-	-	Fic/DOC family
MIICFEMK_01125	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIICFEMK_01126	5.99e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MIICFEMK_01127	2.69e-255	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_01128	5.19e-273	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MIICFEMK_01129	1.41e-156	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIICFEMK_01130	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIICFEMK_01131	1.95e-252	-	-	-	I	-	-	-	PAP2 superfamily
MIICFEMK_01132	0.0	-	-	-	M	-	-	-	PA domain
MIICFEMK_01133	4.46e-173	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MIICFEMK_01134	6.29e-296	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MIICFEMK_01135	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
MIICFEMK_01136	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIICFEMK_01137	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MIICFEMK_01138	8.35e-24	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MIICFEMK_01139	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MIICFEMK_01140	1.77e-148	-	-	-	-	-	-	-	-
MIICFEMK_01141	5.34e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIICFEMK_01143	2.36e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MIICFEMK_01144	2.68e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MIICFEMK_01145	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIICFEMK_01146	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
MIICFEMK_01147	1.88e-273	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
MIICFEMK_01148	1.04e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
MIICFEMK_01149	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
MIICFEMK_01150	1.3e-20	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
MIICFEMK_01152	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
MIICFEMK_01153	6.74e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
MIICFEMK_01154	1.34e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
MIICFEMK_01156	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIICFEMK_01157	1.57e-282	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
MIICFEMK_01158	5.26e-130	-	-	-	-	-	-	-	-
MIICFEMK_01159	1.86e-63	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
MIICFEMK_01160	5.26e-38	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MIICFEMK_01161	1.16e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MIICFEMK_01162	0.0	-	-	-	-	-	-	-	-
MIICFEMK_01163	2.82e-36	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
MIICFEMK_01164	5.53e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIICFEMK_01165	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_01166	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
MIICFEMK_01167	0.0	-	-	-	V	-	-	-	ABC transporter permease
MIICFEMK_01168	1.03e-272	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIICFEMK_01169	3.42e-178	-	-	-	T	ko:K06950	-	ko00000	HD domain
MIICFEMK_01170	9.99e-213	-	-	-	S	-	-	-	Glutamine amidotransferase domain
MIICFEMK_01171	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MIICFEMK_01172	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MIICFEMK_01173	0.0	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
MIICFEMK_01175	7.84e-113	-	-	-	K	-	-	-	Transcriptional regulator
MIICFEMK_01176	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIICFEMK_01177	1.14e-171	-	-	-	-	-	-	-	-
MIICFEMK_01178	1.6e-83	-	-	-	-	-	-	-	-
MIICFEMK_01179	2.05e-224	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIICFEMK_01180	1.05e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MIICFEMK_01182	2.47e-179	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MIICFEMK_01183	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
MIICFEMK_01184	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
MIICFEMK_01185	9.12e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
MIICFEMK_01186	2.72e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
MIICFEMK_01187	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIICFEMK_01188	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MIICFEMK_01189	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
MIICFEMK_01190	3.34e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIICFEMK_01191	1.84e-180	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MIICFEMK_01192	4.98e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
MIICFEMK_01193	9.16e-182	nfrA	-	-	C	-	-	-	Nitroreductase family
MIICFEMK_01194	2.45e-61	-	-	-	-	-	-	-	-
MIICFEMK_01195	6e-150	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
MIICFEMK_01196	8.56e-119	-	-	-	S	-	-	-	Transcription factor WhiB
MIICFEMK_01197	7.04e-57	-	-	-	-	-	-	-	-
MIICFEMK_01198	8.63e-257	-	-	-	S	-	-	-	Helix-turn-helix domain
MIICFEMK_01199	6.92e-41	-	-	-	-	-	-	-	-
MIICFEMK_01200	9.89e-150	-	-	-	-	-	-	-	-
MIICFEMK_01202	2.85e-65	-	-	-	-	-	-	-	-
MIICFEMK_01203	4.36e-46	-	-	-	-	-	-	-	-
MIICFEMK_01204	1.57e-223	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIICFEMK_01205	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIICFEMK_01206	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
MIICFEMK_01207	6.96e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
MIICFEMK_01208	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIICFEMK_01209	3.63e-54	-	-	-	-	-	-	-	-
MIICFEMK_01210	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MIICFEMK_01211	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIICFEMK_01212	1.26e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
MIICFEMK_01213	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MIICFEMK_01214	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIICFEMK_01215	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MIICFEMK_01216	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIICFEMK_01217	6.56e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIICFEMK_01218	1.44e-310	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIICFEMK_01221	9e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MIICFEMK_01222	8.28e-291	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIICFEMK_01223	4.26e-222	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MIICFEMK_01224	6.09e-152	safC	-	-	S	-	-	-	O-methyltransferase
MIICFEMK_01225	2.15e-236	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MIICFEMK_01226	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
MIICFEMK_01227	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MIICFEMK_01228	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MIICFEMK_01229	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
MIICFEMK_01230	3.62e-212	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MIICFEMK_01231	1.4e-201	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIICFEMK_01232	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
MIICFEMK_01233	1.53e-215	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_01234	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MIICFEMK_01235	0.0	-	-	-	I	-	-	-	PAP2 superfamily
MIICFEMK_01236	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_01237	0.0	-	-	-	T	-	-	-	Histidine kinase
MIICFEMK_01238	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
MIICFEMK_01239	3.51e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIICFEMK_01240	2.08e-213	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
MIICFEMK_01241	1.1e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MIICFEMK_01242	2.43e-240	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MIICFEMK_01243	1.63e-237	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MIICFEMK_01244	8.13e-263	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIICFEMK_01245	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_01246	1.73e-290	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MIICFEMK_01247	4.5e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIICFEMK_01248	4.77e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIICFEMK_01250	1.9e-39	-	-	-	-	-	-	-	-
MIICFEMK_01251	1.27e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MIICFEMK_01252	9.07e-151	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MIICFEMK_01253	4.67e-75	-	-	-	S	-	-	-	competence protein
MIICFEMK_01254	8.1e-11	-	-	-	-	-	-	-	-
MIICFEMK_01258	4.3e-143	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
MIICFEMK_01259	2.8e-50	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
MIICFEMK_01260	2.73e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_01261	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
MIICFEMK_01262	6.35e-201	-	-	-	J	-	-	-	Methyltransferase domain
MIICFEMK_01263	4.93e-107	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MIICFEMK_01264	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MIICFEMK_01265	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIICFEMK_01267	1.1e-30	-	-	-	-	-	-	-	-
MIICFEMK_01268	4.68e-265	-	-	-	S	-	-	-	Short C-terminal domain
MIICFEMK_01269	1.1e-112	-	-	-	S	-	-	-	Helix-turn-helix
MIICFEMK_01270	7.03e-86	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MIICFEMK_01271	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MIICFEMK_01272	1.39e-27	-	-	-	-	-	-	-	-
MIICFEMK_01273	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MIICFEMK_01274	3.7e-161	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MIICFEMK_01275	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
MIICFEMK_01277	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MIICFEMK_01278	3.72e-152	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
MIICFEMK_01279	2.58e-186	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MIICFEMK_01280	3.71e-239	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MIICFEMK_01281	4.12e-79	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MIICFEMK_01282	6.99e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MIICFEMK_01283	2.75e-304	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
MIICFEMK_01284	3.06e-108	-	-	-	K	-	-	-	AraC-like ligand binding domain
MIICFEMK_01286	6.75e-67	-	-	-	IQ	-	-	-	oxidoreductase activity
MIICFEMK_01287	2.65e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MIICFEMK_01288	1.67e-173	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_01289	1.11e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIICFEMK_01290	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIICFEMK_01291	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
MIICFEMK_01292	2.99e-138	-	-	-	-	-	-	-	-
MIICFEMK_01293	1.58e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIICFEMK_01294	3.67e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIICFEMK_01295	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIICFEMK_01296	1.14e-312	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MIICFEMK_01297	1.69e-232	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIICFEMK_01298	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MIICFEMK_01299	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIICFEMK_01300	8.84e-226	-	-	-	L	-	-	-	Phage integrase family
MIICFEMK_01301	2.89e-126	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
MIICFEMK_01302	2.21e-199	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
MIICFEMK_01303	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
MIICFEMK_01304	4.79e-134	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
MIICFEMK_01305	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
MIICFEMK_01306	3.34e-252	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIICFEMK_01307	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MIICFEMK_01308	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MIICFEMK_01309	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MIICFEMK_01310	3.54e-185	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIICFEMK_01311	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIICFEMK_01313	3.07e-227	-	-	-	L	-	-	-	Tetratricopeptide repeat
MIICFEMK_01314	1.25e-241	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MIICFEMK_01316	3.26e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MIICFEMK_01317	4.57e-143	-	-	-	-	-	-	-	-
MIICFEMK_01318	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MIICFEMK_01319	9.68e-142	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
MIICFEMK_01320	5.33e-163	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
MIICFEMK_01321	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIICFEMK_01322	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MIICFEMK_01323	3.57e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MIICFEMK_01324	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MIICFEMK_01325	7.39e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_01326	1.77e-162	-	-	-	S	-	-	-	ABC-2 family transporter protein
MIICFEMK_01327	3.24e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
MIICFEMK_01328	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
MIICFEMK_01329	2.93e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIICFEMK_01330	1.72e-118	-	-	-	-	-	-	-	-
MIICFEMK_01331	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIICFEMK_01332	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIICFEMK_01334	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIICFEMK_01335	1.01e-87	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIICFEMK_01336	1.65e-177	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MIICFEMK_01337	1.08e-101	-	-	-	S	-	-	-	Bacterial PH domain
MIICFEMK_01338	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
MIICFEMK_01340	6.58e-159	-	-	-	-	-	-	-	-
MIICFEMK_01341	1.99e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
MIICFEMK_01342	1.4e-187	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
MIICFEMK_01343	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
MIICFEMK_01344	3.66e-187	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
MIICFEMK_01345	5.57e-247	-	-	-	V	-	-	-	VanZ like family
MIICFEMK_01346	5.99e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MIICFEMK_01347	2.67e-124	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MIICFEMK_01348	8.8e-204	-	-	-	-	-	-	-	-
MIICFEMK_01350	9.04e-126	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MIICFEMK_01351	3.19e-38	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
MIICFEMK_01352	2.79e-226	-	-	-	M	-	-	-	heme binding
MIICFEMK_01353	3.23e-104	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIICFEMK_01354	2.47e-109	-	-	-	-	-	-	-	-
MIICFEMK_01355	1.4e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
MIICFEMK_01356	5e-102	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
MIICFEMK_01357	8.09e-235	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MIICFEMK_01359	2.73e-42	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
MIICFEMK_01360	3.93e-49	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
MIICFEMK_01361	2.71e-74	-	-	-	K	-	-	-	Transcriptional regulator
MIICFEMK_01362	6.56e-118	-	-	-	K	-	-	-	FR47-like protein
MIICFEMK_01363	3.32e-155	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MIICFEMK_01364	7.91e-83	-	-	-	K	-	-	-	Protein of unknown function, DUF488
MIICFEMK_01365	1.71e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MIICFEMK_01366	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_01367	2.37e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
MIICFEMK_01368	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MIICFEMK_01369	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
MIICFEMK_01370	4.05e-207	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MIICFEMK_01371	1.72e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MIICFEMK_01372	1.12e-215	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MIICFEMK_01373	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MIICFEMK_01374	1.21e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MIICFEMK_01375	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MIICFEMK_01376	2.59e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MIICFEMK_01377	6.31e-153	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MIICFEMK_01378	9.87e-204	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
MIICFEMK_01379	4.23e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
MIICFEMK_01380	2.66e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIICFEMK_01382	1.63e-167	-	-	-	M	-	-	-	Peptidase family M23
MIICFEMK_01383	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIICFEMK_01384	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MIICFEMK_01385	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
MIICFEMK_01386	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
MIICFEMK_01387	5.1e-118	-	-	-	-	-	-	-	-
MIICFEMK_01388	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MIICFEMK_01389	1.05e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIICFEMK_01390	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MIICFEMK_01391	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIICFEMK_01392	3.84e-165	-	-	-	S	-	-	-	alpha beta
MIICFEMK_01393	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MIICFEMK_01394	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIICFEMK_01395	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MIICFEMK_01396	2.19e-291	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIICFEMK_01397	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIICFEMK_01398	6.57e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIICFEMK_01399	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIICFEMK_01400	1.15e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MIICFEMK_01401	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MIICFEMK_01402	1.93e-215	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
MIICFEMK_01403	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
MIICFEMK_01404	8.35e-229	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MIICFEMK_01405	1.28e-277	-	-	-	GK	-	-	-	ROK family
MIICFEMK_01406	1.41e-263	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
MIICFEMK_01407	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MIICFEMK_01408	8.31e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIICFEMK_01409	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MIICFEMK_01410	1.34e-177	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MIICFEMK_01411	0.0	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIICFEMK_01412	2.13e-151	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MIICFEMK_01414	6.28e-77	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MIICFEMK_01415	6.79e-119	-	-	-	-	-	-	-	-
MIICFEMK_01416	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIICFEMK_01417	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIICFEMK_01418	2.6e-231	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
MIICFEMK_01419	1.23e-226	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MIICFEMK_01420	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MIICFEMK_01421	6.71e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MIICFEMK_01422	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIICFEMK_01423	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MIICFEMK_01424	1.23e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MIICFEMK_01425	2.44e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MIICFEMK_01426	3.01e-308	-	-	-	V	-	-	-	MatE
MIICFEMK_01428	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MIICFEMK_01429	1.88e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MIICFEMK_01430	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIICFEMK_01431	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
MIICFEMK_01432	2.42e-281	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIICFEMK_01433	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIICFEMK_01434	8.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
MIICFEMK_01435	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIICFEMK_01436	4.1e-199	-	-	-	S	-	-	-	PAC2 family
MIICFEMK_01440	0.0	-	-	-	-	-	-	-	-
MIICFEMK_01443	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIICFEMK_01444	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIICFEMK_01445	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
MIICFEMK_01446	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MIICFEMK_01447	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIICFEMK_01448	1.83e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIICFEMK_01449	6.91e-259	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIICFEMK_01450	5.06e-70	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MIICFEMK_01451	3.9e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIICFEMK_01452	2.85e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIICFEMK_01453	9.52e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIICFEMK_01454	3.85e-314	-	-	-	-	-	-	-	-
MIICFEMK_01455	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MIICFEMK_01456	5.17e-56	-	-	-	-	-	-	-	-
MIICFEMK_01457	9.88e-167	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MIICFEMK_01458	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MIICFEMK_01459	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MIICFEMK_01460	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIICFEMK_01461	4.37e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIICFEMK_01462	3.09e-244	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIICFEMK_01463	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
MIICFEMK_01464	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
MIICFEMK_01465	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MIICFEMK_01466	1.1e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIICFEMK_01467	2.27e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIICFEMK_01468	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
MIICFEMK_01469	2.65e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MIICFEMK_01470	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MIICFEMK_01471	6.86e-154	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MIICFEMK_01472	8.13e-82	-	-	-	-	-	-	-	-
MIICFEMK_01474	1.48e-31	-	-	-	L	-	-	-	DNA integration
MIICFEMK_01475	6.19e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MIICFEMK_01476	1.23e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
MIICFEMK_01479	5.93e-183	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MIICFEMK_01480	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MIICFEMK_01481	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
MIICFEMK_01482	2.14e-69	-	-	-	-	-	-	-	-
MIICFEMK_01483	0.0	-	-	-	K	-	-	-	WYL domain
MIICFEMK_01484	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MIICFEMK_01486	8.1e-78	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MIICFEMK_01487	7.48e-186	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MIICFEMK_01488	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIICFEMK_01489	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MIICFEMK_01490	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MIICFEMK_01491	6.5e-119	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
MIICFEMK_01492	1.66e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MIICFEMK_01493	9.14e-25	-	-	-	-	-	-	-	-
MIICFEMK_01494	1.02e-64	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
MIICFEMK_01495	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
MIICFEMK_01496	1.99e-284	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
MIICFEMK_01497	6.48e-91	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
MIICFEMK_01498	1.13e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MIICFEMK_01499	1.51e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MIICFEMK_01500	2.21e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
MIICFEMK_01501	5.66e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
MIICFEMK_01502	9.36e-310	-	-	-	V	-	-	-	MatE
MIICFEMK_01503	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIICFEMK_01504	1.76e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MIICFEMK_01505	1.4e-22	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIICFEMK_01506	1.05e-217	-	-	-	-	-	-	-	-
MIICFEMK_01507	2.55e-247	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MIICFEMK_01508	2.41e-23	-	-	-	K	-	-	-	MerR family regulatory protein
MIICFEMK_01509	1.75e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIICFEMK_01510	1.01e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIICFEMK_01511	7.23e-200	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MIICFEMK_01512	2.31e-230	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
MIICFEMK_01513	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIICFEMK_01514	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MIICFEMK_01515	2.23e-233	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MIICFEMK_01516	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MIICFEMK_01518	2.35e-208	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MIICFEMK_01519	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIICFEMK_01520	8.29e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
MIICFEMK_01521	2e-265	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIICFEMK_01522	3.98e-228	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MIICFEMK_01523	1.18e-30	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
MIICFEMK_01524	1.59e-110	-	-	-	E	-	-	-	Rard protein
MIICFEMK_01525	9.32e-40	-	-	-	-	-	-	-	-
MIICFEMK_01526	1.22e-271	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MIICFEMK_01527	1.35e-38	-	-	-	-	ko:K07485	-	ko00000	-
MIICFEMK_01528	5.67e-224	-	-	-	L	ko:K07485	-	ko00000	Transposase
MIICFEMK_01529	2.25e-77	-	-	-	S	-	-	-	Short C-terminal domain
MIICFEMK_01530	1.07e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MIICFEMK_01531	4.33e-68	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
MIICFEMK_01532	6.29e-192	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
MIICFEMK_01533	5.32e-208	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MIICFEMK_01534	2.88e-313	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
MIICFEMK_01535	5.23e-107	-	-	-	-	-	-	-	-
MIICFEMK_01536	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MIICFEMK_01537	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
MIICFEMK_01538	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MIICFEMK_01539	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
MIICFEMK_01540	1.93e-17	-	-	-	S	ko:K07149	-	ko00000	Membrane
MIICFEMK_01541	1.5e-308	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MIICFEMK_01542	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIICFEMK_01543	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MIICFEMK_01544	4.63e-175	-	-	-	S	-	-	-	UPF0126 domain
MIICFEMK_01545	4.55e-95	-	-	-	T	-	-	-	RNA ligase
MIICFEMK_01546	1.11e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
MIICFEMK_01547	1.94e-127	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIICFEMK_01548	3.61e-243	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MIICFEMK_01549	1.72e-306	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIICFEMK_01550	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
MIICFEMK_01551	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
MIICFEMK_01552	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MIICFEMK_01553	5.62e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIICFEMK_01554	0.0	corC	-	-	S	-	-	-	CBS domain
MIICFEMK_01555	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIICFEMK_01556	4.28e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
MIICFEMK_01557	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MIICFEMK_01558	6.24e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIICFEMK_01560	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
MIICFEMK_01561	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIICFEMK_01562	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MIICFEMK_01563	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MIICFEMK_01564	4.22e-305	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIICFEMK_01565	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MIICFEMK_01566	1.69e-297	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
MIICFEMK_01567	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
MIICFEMK_01568	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIICFEMK_01569	1.31e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
MIICFEMK_01570	3.46e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_01571	2.14e-21	-	-	-	-	-	-	-	-
MIICFEMK_01572	1.87e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MIICFEMK_01573	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIICFEMK_01574	4.5e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIICFEMK_01575	5.3e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
MIICFEMK_01576	2e-250	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIICFEMK_01577	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIICFEMK_01578	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIICFEMK_01579	7.33e-50	-	-	-	-	-	-	-	-
MIICFEMK_01580	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MIICFEMK_01581	4.95e-172	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MIICFEMK_01582	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIICFEMK_01583	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIICFEMK_01584	3.16e-171	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MIICFEMK_01585	1.87e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MIICFEMK_01586	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
MIICFEMK_01587	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MIICFEMK_01588	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MIICFEMK_01589	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIICFEMK_01590	7.11e-309	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
MIICFEMK_01592	8.63e-56	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIICFEMK_01594	5.11e-146	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
MIICFEMK_01595	1.13e-53	-	-	-	-	-	-	-	-
MIICFEMK_01596	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
MIICFEMK_01597	1.43e-223	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MIICFEMK_01598	1.23e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
MIICFEMK_01599	7.23e-85	-	-	-	D	-	-	-	MobA/MobL family
MIICFEMK_01600	8.14e-117	-	-	-	-	-	-	-	-
MIICFEMK_01602	9.83e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
MIICFEMK_01603	5.39e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MIICFEMK_01604	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIICFEMK_01605	5.44e-184	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MIICFEMK_01606	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
MIICFEMK_01607	1.73e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
MIICFEMK_01608	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MIICFEMK_01609	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MIICFEMK_01611	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIICFEMK_01612	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
MIICFEMK_01613	1.83e-198	-	-	-	-	-	-	-	-
MIICFEMK_01614	3.02e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MIICFEMK_01615	1.51e-303	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MIICFEMK_01616	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
MIICFEMK_01617	7.41e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
MIICFEMK_01618	2.18e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MIICFEMK_01619	7.97e-223	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MIICFEMK_01620	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MIICFEMK_01621	2.59e-201	-	-	-	O	-	-	-	Thioredoxin
MIICFEMK_01623	2.01e-276	rpfB	-	-	S	ko:K21688	-	ko00000	G5
MIICFEMK_01624	6.28e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIICFEMK_01625	8.91e-212	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIICFEMK_01626	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MIICFEMK_01627	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
MIICFEMK_01628	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
MIICFEMK_01629	0.0	-	-	-	M	-	-	-	Conserved repeat domain
MIICFEMK_01630	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MIICFEMK_01631	5.58e-258	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIICFEMK_01632	9.38e-311	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MIICFEMK_01633	1.05e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MIICFEMK_01634	2.59e-162	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MIICFEMK_01635	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
MIICFEMK_01636	2.11e-227	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
MIICFEMK_01637	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MIICFEMK_01638	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIICFEMK_01639	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIICFEMK_01640	1.95e-308	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIICFEMK_01641	1.36e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MIICFEMK_01642	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIICFEMK_01643	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIICFEMK_01644	2.04e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
MIICFEMK_01646	4.52e-239	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MIICFEMK_01647	2.29e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
MIICFEMK_01648	7.56e-290	-	-	-	I	-	-	-	Serine aminopeptidase, S33
MIICFEMK_01649	7.69e-11	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_01650	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
MIICFEMK_01651	4.93e-141	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MIICFEMK_01652	0.0	-	2.1.1.72	-	L	ko:K07317	-	ko00000,ko01000,ko02048	Eco57I restriction-modification methylase
MIICFEMK_01653	7.78e-235	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	BsuBI/PstI restriction endonuclease C-terminus
MIICFEMK_01654	1.49e-290	-	-	-	-	-	-	-	-
MIICFEMK_01656	8.1e-236	-	-	-	L	-	-	-	Phage integrase family
MIICFEMK_01657	9.53e-07	-	-	-	M	-	-	-	PA domain
MIICFEMK_01658	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MIICFEMK_01659	8e-163	gntR	-	-	K	-	-	-	FCD
MIICFEMK_01660	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIICFEMK_01661	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
MIICFEMK_01664	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MIICFEMK_01665	3.09e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_01666	1.03e-100	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIICFEMK_01667	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MIICFEMK_01668	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MIICFEMK_01669	2.08e-175	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
MIICFEMK_01670	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MIICFEMK_01671	4.89e-241	-	-	-	EG	-	-	-	EamA-like transporter family
MIICFEMK_01672	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MIICFEMK_01673	2.3e-122	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MIICFEMK_01674	4.99e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MIICFEMK_01675	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MIICFEMK_01676	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MIICFEMK_01677	9.66e-309	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MIICFEMK_01678	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIICFEMK_01679	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MIICFEMK_01680	2.5e-197	-	-	-	S	-	-	-	Amidohydrolase family
MIICFEMK_01681	3.86e-21	-	-	-	S	-	-	-	Amidohydrolase family
MIICFEMK_01682	4.09e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
MIICFEMK_01683	1.2e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MIICFEMK_01684	5.42e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
MIICFEMK_01685	2.26e-143	-	-	-	T	-	-	-	protein histidine kinase activity
MIICFEMK_01686	4.32e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIICFEMK_01687	1.23e-34	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MIICFEMK_01688	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MIICFEMK_01689	3.57e-235	-	-	GT2	M	ko:K13670	-	ko00000,ko01000	Glycosyltransferase like family 2
MIICFEMK_01690	6.25e-176	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MIICFEMK_01691	1.56e-159	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MIICFEMK_01692	1.38e-158	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01693	2.09e-159	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01694	3.24e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01695	2.28e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01696	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
MIICFEMK_01697	0.0	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MIICFEMK_01698	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
MIICFEMK_01699	6.01e-246	-	-	-	I	-	-	-	Acyltransferase family
MIICFEMK_01700	5.05e-93	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
MIICFEMK_01701	5.35e-107	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	transposase activity
MIICFEMK_01702	4.94e-105	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01703	1.58e-35	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01704	3.08e-207	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01705	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01706	3.27e-184	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MIICFEMK_01707	1.02e-194	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MIICFEMK_01708	2.86e-130	-	-	-	L	-	-	-	PFAM Integrase catalytic
MIICFEMK_01709	2.77e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MIICFEMK_01710	1.79e-138	-	-	-	-	-	-	-	-
MIICFEMK_01711	1.31e-57	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MIICFEMK_01712	9.11e-69	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MIICFEMK_01713	2.7e-59	-	-	-	L	ko:K07483	-	ko00000	transposase activity
MIICFEMK_01714	1.1e-31	-	-	-	-	-	-	-	-
MIICFEMK_01715	2.49e-14	-	-	-	L	ko:K07485	-	ko00000	Transposase
MIICFEMK_01716	1.9e-51	-	-	-	L	-	-	-	Transposase
MIICFEMK_01717	9.29e-220	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIICFEMK_01718	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIICFEMK_01719	3.56e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIICFEMK_01720	2.32e-197	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MIICFEMK_01721	1.21e-306	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MIICFEMK_01722	1.03e-141	-	-	-	-	-	-	-	-
MIICFEMK_01723	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MIICFEMK_01724	7.73e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MIICFEMK_01725	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MIICFEMK_01726	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIICFEMK_01727	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIICFEMK_01728	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MIICFEMK_01729	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIICFEMK_01730	1.45e-312	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
MIICFEMK_01731	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIICFEMK_01732	4.53e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MIICFEMK_01733	5.62e-294	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MIICFEMK_01734	2.12e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
MIICFEMK_01736	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIICFEMK_01737	5.85e-228	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
MIICFEMK_01738	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIICFEMK_01739	6e-290	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIICFEMK_01740	2.66e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MIICFEMK_01741	1.53e-60	-	-	-	-	-	-	-	-
MIICFEMK_01742	3.19e-198	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
MIICFEMK_01743	2.14e-259	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
MIICFEMK_01744	6.34e-33	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
MIICFEMK_01745	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
MIICFEMK_01746	7.57e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MIICFEMK_01747	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIICFEMK_01748	1.79e-61	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MIICFEMK_01749	3.82e-180	-	-	-	S	-	-	-	cobalamin synthesis protein
MIICFEMK_01750	2.52e-208	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MIICFEMK_01752	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
MIICFEMK_01753	0.0	-	-	-	S	-	-	-	Putative esterase
MIICFEMK_01754	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MIICFEMK_01755	1.26e-305	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MIICFEMK_01756	2.98e-245	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MIICFEMK_01757	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIICFEMK_01758	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
MIICFEMK_01759	9.82e-45	-	-	-	-	-	-	-	-
MIICFEMK_01760	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIICFEMK_01761	7.5e-43	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MIICFEMK_01762	1.1e-188	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MIICFEMK_01763	2.2e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
MIICFEMK_01764	4.17e-142	-	-	-	-	-	-	-	-
MIICFEMK_01765	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MIICFEMK_01766	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MIICFEMK_01767	4.7e-299	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIICFEMK_01768	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
MIICFEMK_01769	4.23e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MIICFEMK_01770	1.33e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MIICFEMK_01772	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIICFEMK_01773	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIICFEMK_01774	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIICFEMK_01775	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIICFEMK_01776	2.19e-101	-	-	-	I	-	-	-	PAP2 superfamily
MIICFEMK_01777	7.43e-265	-	-	-	S	-	-	-	Esterase-like activity of phytase
MIICFEMK_01778	3.95e-250	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MIICFEMK_01780	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIICFEMK_01781	1.01e-150	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIICFEMK_01782	1.4e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MIICFEMK_01783	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MIICFEMK_01784	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MIICFEMK_01785	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MIICFEMK_01786	1.44e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MIICFEMK_01787	0.0	-	-	-	T	-	-	-	Histidine kinase
MIICFEMK_01788	2.17e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MIICFEMK_01789	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MIICFEMK_01790	1.22e-220	-	-	-	EG	-	-	-	EamA-like transporter family
MIICFEMK_01791	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
MIICFEMK_01792	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIICFEMK_01793	1.26e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIICFEMK_01794	1.89e-176	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MIICFEMK_01795	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MIICFEMK_01796	4.16e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIICFEMK_01797	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MIICFEMK_01798	1.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MIICFEMK_01799	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
MIICFEMK_01800	5.43e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIICFEMK_01801	1.97e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MIICFEMK_01804	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIICFEMK_01805	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIICFEMK_01806	4.2e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIICFEMK_01807	2.64e-141	-	-	-	-	-	-	-	-
MIICFEMK_01808	8.72e-173	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MIICFEMK_01809	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
MIICFEMK_01810	3.16e-257	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MIICFEMK_01811	4.85e-158	-	-	-	-	-	-	-	-
MIICFEMK_01812	1.99e-262	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIICFEMK_01813	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MIICFEMK_01814	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
MIICFEMK_01815	1.68e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MIICFEMK_01816	1.65e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MIICFEMK_01817	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MIICFEMK_01818	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MIICFEMK_01819	3.3e-300	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MIICFEMK_01820	1.14e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
MIICFEMK_01821	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
MIICFEMK_01822	2.91e-109	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MIICFEMK_01823	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIICFEMK_01824	2.33e-39	-	-	-	-	-	-	-	-
MIICFEMK_01826	2.27e-266	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
MIICFEMK_01827	1.78e-89	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
MIICFEMK_01828	9.55e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MIICFEMK_01830	4.23e-268	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MIICFEMK_01831	3.34e-314	intA	-	-	L	-	-	-	Phage integrase family
MIICFEMK_01832	1.34e-182	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MIICFEMK_01833	1.3e-36	-	-	-	-	-	-	-	-
MIICFEMK_01834	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
MIICFEMK_01835	5.33e-36	-	-	-	-	-	-	-	-
MIICFEMK_01836	9.88e-180	-	-	-	-	-	-	-	-
MIICFEMK_01837	5.06e-83	-	-	-	S	-	-	-	PrgI family protein
MIICFEMK_01838	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MIICFEMK_01839	1.74e-272	-	-	-	M	-	-	-	CHAP domain
MIICFEMK_01841	6.43e-205	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
MIICFEMK_01842	3.08e-123	-	-	-	K	-	-	-	DNA binding
MIICFEMK_01843	1.66e-127	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
MIICFEMK_01844	6.84e-18	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
MIICFEMK_01845	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
MIICFEMK_01846	7.59e-41	-	-	-	-	-	-	-	-
MIICFEMK_01847	1.19e-52	-	-	-	-	-	-	-	-
MIICFEMK_01848	0.0	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIICFEMK_01850	0.0	-	-	-	-	-	-	-	-
MIICFEMK_01851	2.38e-217	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
MIICFEMK_01852	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
MIICFEMK_01853	1.33e-67	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MIICFEMK_01854	6.75e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
MIICFEMK_01855	5.27e-69	-	-	-	-	-	-	-	-
MIICFEMK_01856	3.6e-85	-	-	-	-	-	-	-	-
MIICFEMK_01857	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
MIICFEMK_01858	1.35e-108	-	-	-	-	-	-	-	-
MIICFEMK_01859	3.35e-87	-	-	-	-	-	-	-	-
MIICFEMK_01860	7.9e-74	-	-	-	-	-	-	-	-
MIICFEMK_01861	7.14e-295	-	-	-	S	-	-	-	HipA-like C-terminal domain
MIICFEMK_01862	1.47e-281	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
MIICFEMK_01863	5.27e-179	-	-	-	L	-	-	-	Integrase core domain