ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HGHNDNDD_00001 1.67e-250 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGHNDNDD_00002 2e-114 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGHNDNDD_00003 5.06e-234 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGHNDNDD_00004 4.04e-243 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HGHNDNDD_00005 2.15e-236 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HGHNDNDD_00006 2.29e-68 - - - - - - - -
HGHNDNDD_00007 1.11e-176 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGHNDNDD_00008 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGHNDNDD_00009 1.12e-244 - - - V - - - Acetyltransferase (GNAT) domain
HGHNDNDD_00010 3.05e-63 - - - V - - - Acetyltransferase (GNAT) domain
HGHNDNDD_00011 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HGHNDNDD_00012 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
HGHNDNDD_00013 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
HGHNDNDD_00014 6.19e-125 - - - F - - - NUDIX domain
HGHNDNDD_00015 5.85e-313 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HGHNDNDD_00016 1.15e-193 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHNDNDD_00017 1.85e-265 - - - GK - - - ROK family
HGHNDNDD_00018 6.7e-210 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_00019 1.64e-281 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_00020 1.94e-215 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HGHNDNDD_00021 6.72e-29 - - - G - - - Major Facilitator Superfamily
HGHNDNDD_00022 1.01e-14 - - - G - - - Major Facilitator Superfamily
HGHNDNDD_00024 1.74e-112 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGHNDNDD_00026 4.6e-228 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
HGHNDNDD_00027 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HGHNDNDD_00028 8e-275 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGHNDNDD_00029 9.99e-288 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
HGHNDNDD_00030 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGHNDNDD_00031 9.14e-263 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGHNDNDD_00032 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGHNDNDD_00033 1.51e-199 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGHNDNDD_00034 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
HGHNDNDD_00035 3.52e-63 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HGHNDNDD_00036 2.43e-242 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGHNDNDD_00037 2.33e-120 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HGHNDNDD_00038 0.0 - - - L - - - DNA helicase
HGHNDNDD_00039 4.79e-292 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HGHNDNDD_00041 4.08e-101 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGHNDNDD_00042 2.04e-67 - - - M - - - Lysin motif
HGHNDNDD_00043 4.13e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGHNDNDD_00044 2.3e-206 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHNDNDD_00045 1.61e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HGHNDNDD_00046 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGHNDNDD_00047 2.83e-159 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
HGHNDNDD_00048 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
HGHNDNDD_00049 3.05e-280 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
HGHNDNDD_00050 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HGHNDNDD_00051 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
HGHNDNDD_00052 7.13e-169 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
HGHNDNDD_00053 2.07e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGHNDNDD_00054 7.57e-163 - - - - - - - -
HGHNDNDD_00055 4.75e-144 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
HGHNDNDD_00056 1.57e-279 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGHNDNDD_00057 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGHNDNDD_00058 1.02e-71 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
HGHNDNDD_00059 3.87e-199 - - - S - - - Aldo/keto reductase family
HGHNDNDD_00060 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HGHNDNDD_00061 5.76e-212 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
HGHNDNDD_00062 1.55e-170 - - - S - - - Amidohydrolase
HGHNDNDD_00064 1.16e-90 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00065 2.03e-225 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00066 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_00067 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00068 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00069 7.76e-185 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGHNDNDD_00070 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HGHNDNDD_00071 1.11e-214 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00072 4.22e-193 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00073 6.51e-176 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
HGHNDNDD_00074 1.6e-175 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00075 4.07e-245 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HGHNDNDD_00076 3.05e-281 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HGHNDNDD_00077 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HGHNDNDD_00078 4.78e-120 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGHNDNDD_00079 2.22e-126 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGHNDNDD_00080 5.72e-144 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
HGHNDNDD_00081 8.95e-224 - - - G - - - Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HGHNDNDD_00082 8.01e-305 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2264)
HGHNDNDD_00083 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
HGHNDNDD_00084 2.39e-201 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00085 1.19e-169 - - - U ko:K02025,ko:K17242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00086 2.24e-166 - - - U ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00087 1.22e-46 - - - - - - - -
HGHNDNDD_00088 0.0 - - - M - - - Belongs to the glycosyl hydrolase 30 family
HGHNDNDD_00089 1.59e-216 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
HGHNDNDD_00090 3.42e-293 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGHNDNDD_00091 9.95e-82 gntK 2.7.1.12 - F ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Shikimate kinase
HGHNDNDD_00092 3.2e-295 - 4.2.1.8 - M ko:K08323 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 mandelate racemase muconate lactonizing
HGHNDNDD_00093 5.1e-243 mtlD 1.1.1.57, 1.1.1.58 - G ko:K00040,ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
HGHNDNDD_00094 3.23e-223 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Glucuronate isomerase
HGHNDNDD_00095 5.9e-63 - - - FG - - - bis(5'-adenosyl)-triphosphatase activity
HGHNDNDD_00096 2.54e-91 - - - K ko:K02529,ko:K05499 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HGHNDNDD_00097 2.83e-88 - - - K ko:K02529,ko:K05499 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HGHNDNDD_00098 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
HGHNDNDD_00099 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGHNDNDD_00100 1.97e-308 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
HGHNDNDD_00101 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGHNDNDD_00103 3.53e-37 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGHNDNDD_00104 1.63e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HGHNDNDD_00105 1.4e-147 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HGHNDNDD_00106 0.0 - - - EK ko:K03710,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000,ko03000 Alanine-glyoxylate amino-transferase
HGHNDNDD_00107 3.2e-266 - - - P - - - Citrate transporter
HGHNDNDD_00108 9.8e-41 - - - - - - - -
HGHNDNDD_00109 1.34e-50 - - - G - - - Alpha-L-arabinofuranosidase C-terminal domain
HGHNDNDD_00110 2.25e-205 - - - K - - - Helix-turn-helix domain, rpiR family
HGHNDNDD_00113 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00114 9.75e-295 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00115 2.34e-218 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HGHNDNDD_00116 2.48e-56 XK27_01805 - - M - - - Glycosyltransferase like family 2
HGHNDNDD_00117 3.95e-143 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HGHNDNDD_00118 1.41e-76 - - - C - - - Polysaccharide pyruvyl transferase
HGHNDNDD_00120 1.15e-57 - - - M - - - Glycosyltransferase, group 1 family protein
HGHNDNDD_00121 3.68e-175 - - - M - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_00122 6.11e-40 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_00123 1.29e-185 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_00125 7.51e-139 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HGHNDNDD_00126 1.25e-140 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
HGHNDNDD_00127 2.08e-292 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HGHNDNDD_00128 0.0 - - - H - - - Protein of unknown function (DUF4012)
HGHNDNDD_00129 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HGHNDNDD_00130 3.88e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HGHNDNDD_00131 1.06e-180 - - - L - - - Protein of unknown function (DUF1524)
HGHNDNDD_00132 5.13e-211 - - - S - - - Oxidoreductase, aldo keto reductase family protein
HGHNDNDD_00134 0.0 galA 3.2.1.89 - G ko:K01224 - ko00000,ko01000 Glycosyl hydrolase family 53
HGHNDNDD_00135 1.12e-243 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00136 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_00137 7.65e-14 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00139 3.52e-12 - - - - - - - -
HGHNDNDD_00141 1.25e-13 - - - L - - - HTH-like domain
HGHNDNDD_00142 2.78e-27 - - - L - - - PFAM Integrase catalytic
HGHNDNDD_00143 2.75e-108 - - - - - - - -
HGHNDNDD_00144 1.12e-86 - - - - - - - -
HGHNDNDD_00145 1.1e-70 - - - L - - - Transposase, Mutator family
HGHNDNDD_00146 2.92e-110 - - - L - - - Transposase, Mutator family
HGHNDNDD_00148 8.64e-176 - - - L - - - IstB-like ATP binding protein
HGHNDNDD_00149 2.35e-296 - - - L - - - PFAM Integrase catalytic
HGHNDNDD_00153 8.29e-33 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_00154 3.12e-11 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_00155 2.3e-20 - - - K - - - DNA-binding transcriptional activator of the SARP family
HGHNDNDD_00158 1.24e-44 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HGHNDNDD_00159 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HGHNDNDD_00160 2.7e-17 - - - - - - - -
HGHNDNDD_00161 0.0 - - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
HGHNDNDD_00162 2.86e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00163 2.34e-270 - - - G - - - Transmembrane secretion effector
HGHNDNDD_00164 3.47e-306 - - - S - - - HipA-like C-terminal domain
HGHNDNDD_00165 2.07e-50 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HGHNDNDD_00166 5.72e-69 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HGHNDNDD_00167 2.86e-83 - - - S - - - Cupin 2, conserved barrel domain protein
HGHNDNDD_00168 2.11e-69 - - - J - - - Methyltransferase domain
HGHNDNDD_00169 7.81e-79 yccF - - S - - - Inner membrane component domain
HGHNDNDD_00170 1.59e-206 - - - S - - - phosphoesterase or phosphohydrolase
HGHNDNDD_00171 7.14e-310 - - - T - - - RNA ligase
HGHNDNDD_00172 2.42e-16 - - - S - - - Unextendable partial coding region
HGHNDNDD_00173 1.24e-183 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
HGHNDNDD_00174 4.68e-295 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HGHNDNDD_00175 1.06e-237 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HGHNDNDD_00176 2.03e-34 - - - G - - - Acyltransferase family
HGHNDNDD_00177 3.33e-67 - - - S - - - enterobacterial common antigen metabolic process
HGHNDNDD_00178 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00179 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
HGHNDNDD_00181 2.86e-42 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
HGHNDNDD_00182 4.04e-86 - - - S - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_00183 0.0 - - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor
HGHNDNDD_00184 9.9e-116 XK26_06155 - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_00185 2.56e-37 - - - K - - - DNA-templated transcription, initiation
HGHNDNDD_00186 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HGHNDNDD_00187 4.25e-270 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00188 9.52e-205 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHNDNDD_00189 2.79e-224 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGHNDNDD_00190 9.65e-79 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGHNDNDD_00191 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00192 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00193 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HGHNDNDD_00196 2.19e-225 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
HGHNDNDD_00197 8.88e-171 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGHNDNDD_00198 4.49e-185 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGHNDNDD_00199 1.89e-316 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHNDNDD_00200 4.54e-151 - - - - - - - -
HGHNDNDD_00201 4.29e-101 - - - K - - - MerR, DNA binding
HGHNDNDD_00202 5.59e-250 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
HGHNDNDD_00203 1.21e-63 - - - S - - - Protein of unknown function (DUF3039)
HGHNDNDD_00204 9.97e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGHNDNDD_00205 1.5e-148 - - - - - - - -
HGHNDNDD_00206 3.89e-151 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HGHNDNDD_00207 4.87e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HGHNDNDD_00208 6.09e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGHNDNDD_00209 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
HGHNDNDD_00210 8.22e-120 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HGHNDNDD_00211 1.03e-55 - - - S ko:K21495 - ko00000,ko02048 Plasmid stability protein
HGHNDNDD_00212 9.42e-95 vapC - - S ko:K07062 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module. An RNase
HGHNDNDD_00214 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
HGHNDNDD_00215 2.75e-174 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
HGHNDNDD_00216 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HGHNDNDD_00217 2.14e-205 - - - P - - - Cation efflux family
HGHNDNDD_00218 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGHNDNDD_00219 3.65e-268 - - - S - - - Endonuclease/Exonuclease/phosphatase family
HGHNDNDD_00220 8.72e-83 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HGHNDNDD_00221 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HGHNDNDD_00222 5.15e-138 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGHNDNDD_00223 1.83e-258 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HGHNDNDD_00224 9.62e-215 - - - C - - - Oxidoreductase, aldo keto reductase family protein
HGHNDNDD_00225 1.42e-28 - - - - - - - -
HGHNDNDD_00226 1.31e-86 - - - S - - - Predicted membrane protein (DUF2207)
HGHNDNDD_00228 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HGHNDNDD_00229 3.53e-119 lemA - - S ko:K03744 - ko00000 LemA family
HGHNDNDD_00230 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HGHNDNDD_00231 2.04e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGHNDNDD_00232 2.26e-145 - - - - - - - -
HGHNDNDD_00233 8.35e-66 - - - - - - - -
HGHNDNDD_00235 0.0 - - - M - - - LPXTG cell wall anchor motif
HGHNDNDD_00236 0.0 - - - M - - - Conserved repeat domain
HGHNDNDD_00237 1.74e-103 - - - - - - - -
HGHNDNDD_00239 5.52e-148 - - - P - - - Sodium/hydrogen exchanger family
HGHNDNDD_00240 8.55e-97 ams 2.4.1.4 GH13 G ko:K05341 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HGHNDNDD_00241 4.5e-106 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGHNDNDD_00242 1.37e-115 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGHNDNDD_00243 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_00244 2.01e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00245 5.56e-49 - - - L - - - Transposase, Mutator family
HGHNDNDD_00246 4.14e-297 - - - S ko:K07133 - ko00000 AAA domain
HGHNDNDD_00247 2.29e-227 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00248 1.85e-211 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00249 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00250 0.0 - - - P - - - Domain of unknown function (DUF4976)
HGHNDNDD_00251 2.02e-247 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00252 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
HGHNDNDD_00253 1.41e-172 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HGHNDNDD_00254 4.36e-16 - - - L - - - Transposase DDE domain
HGHNDNDD_00255 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HGHNDNDD_00256 4.4e-174 - - - M - - - Mechanosensitive ion channel
HGHNDNDD_00257 5.06e-237 - - - S - - - CAAX protease self-immunity
HGHNDNDD_00258 1.12e-303 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HGHNDNDD_00259 1.18e-198 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00260 8.03e-206 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00261 6.12e-278 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00262 1.73e-292 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HGHNDNDD_00263 9.31e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HGHNDNDD_00264 1.78e-241 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HGHNDNDD_00265 3.27e-83 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
HGHNDNDD_00268 3.19e-151 - - - S - - - CYTH
HGHNDNDD_00269 2.97e-218 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
HGHNDNDD_00270 2.58e-229 - - - - - - - -
HGHNDNDD_00271 4.07e-247 - - - - - - - -
HGHNDNDD_00272 5.97e-215 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
HGHNDNDD_00273 5e-165 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HGHNDNDD_00274 3.62e-65 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HGHNDNDD_00275 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGHNDNDD_00276 3.59e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGHNDNDD_00277 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGHNDNDD_00278 1.29e-194 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHNDNDD_00279 4.77e-99 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGHNDNDD_00280 9.96e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHNDNDD_00281 4.46e-186 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HGHNDNDD_00282 3.5e-263 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGHNDNDD_00284 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
HGHNDNDD_00285 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HGHNDNDD_00286 1.95e-119 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HGHNDNDD_00287 2.89e-112 mntP - - P - - - Probably functions as a manganese efflux pump
HGHNDNDD_00288 1.26e-154 - - - - - - - -
HGHNDNDD_00289 2.67e-179 glnR - - KT - - - Transcriptional regulatory protein, C terminal
HGHNDNDD_00290 6.93e-162 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGHNDNDD_00291 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HGHNDNDD_00292 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGHNDNDD_00293 0.0 - - - S - - - domain protein
HGHNDNDD_00294 1.56e-81 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
HGHNDNDD_00295 3.79e-97 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 Amino-transferase class IV
HGHNDNDD_00296 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGHNDNDD_00297 0.0 - - - H - - - Flavin containing amine oxidoreductase
HGHNDNDD_00298 2.66e-68 - - - S - - - Protein of unknown function (DUF2469)
HGHNDNDD_00299 5.57e-247 - - - J - - - Acetyltransferase (GNAT) domain
HGHNDNDD_00300 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHNDNDD_00301 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGHNDNDD_00302 7.57e-68 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHNDNDD_00303 3.05e-204 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_00304 2.19e-228 - - - - - - - -
HGHNDNDD_00305 9.54e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HGHNDNDD_00306 6.01e-217 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
HGHNDNDD_00307 3.99e-141 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGHNDNDD_00308 1.54e-275 rmuC - - S ko:K09760 - ko00000 RmuC family
HGHNDNDD_00309 1.64e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
HGHNDNDD_00310 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HGHNDNDD_00311 2.54e-161 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HGHNDNDD_00313 1.72e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HGHNDNDD_00314 2.15e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGHNDNDD_00315 4.09e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HGHNDNDD_00316 2.77e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HGHNDNDD_00317 3.31e-238 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHNDNDD_00318 4.99e-196 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGHNDNDD_00319 1.79e-110 - 3.2.1.185 GH127 S ko:K09955,ko:K18205 - ko00000,ko01000 Beta-L-arabinofuranosidase, GH127
HGHNDNDD_00320 6.16e-91 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
HGHNDNDD_00321 0.0 - - - S ko:K03688 - ko00000 ABC1 family
HGHNDNDD_00322 1.91e-52 - - - S - - - granule-associated protein
HGHNDNDD_00323 4.49e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HGHNDNDD_00324 0.0 murE - - M - - - Domain of unknown function (DUF1727)
HGHNDNDD_00325 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HGHNDNDD_00326 4.25e-305 dinF - - V - - - MatE
HGHNDNDD_00327 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
HGHNDNDD_00328 1.27e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
HGHNDNDD_00329 1.59e-304 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
HGHNDNDD_00330 1.19e-233 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGHNDNDD_00331 4.13e-193 icaR - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00332 3.8e-252 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
HGHNDNDD_00333 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HGHNDNDD_00335 0.0 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HGHNDNDD_00336 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGHNDNDD_00337 4.24e-247 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
HGHNDNDD_00338 5.03e-193 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HGHNDNDD_00339 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGHNDNDD_00340 0.0 - - - S - - - Putative ABC-transporter type IV
HGHNDNDD_00341 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HGHNDNDD_00342 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HGHNDNDD_00343 1.62e-130 - - - K - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_00344 1.68e-102 - - - S - - - FMN_bind
HGHNDNDD_00345 1.39e-187 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00346 4.45e-275 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_00347 3.49e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00348 4.79e-290 - - - S - - - Predicted membrane protein (DUF2318)
HGHNDNDD_00349 1.89e-159 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
HGHNDNDD_00350 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
HGHNDNDD_00354 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGHNDNDD_00356 4.93e-223 - - - S - - - Protein of unknown function (DUF805)
HGHNDNDD_00357 6.21e-107 - 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HGHNDNDD_00358 4.08e-204 - - - - - - - -
HGHNDNDD_00359 4.17e-157 - - - G - - - Phosphoglycerate mutase family
HGHNDNDD_00360 0.0 - - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_00361 3.69e-124 - - - S - - - GtrA-like protein
HGHNDNDD_00362 1.11e-81 - - - S - - - Macrophage migration inhibitory factor (MIF)
HGHNDNDD_00363 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
HGHNDNDD_00364 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
HGHNDNDD_00365 8.37e-137 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HGHNDNDD_00366 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHNDNDD_00368 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HGHNDNDD_00369 7.11e-135 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00370 3.74e-265 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HGHNDNDD_00371 1.01e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGHNDNDD_00372 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGHNDNDD_00373 3.09e-228 - - - I - - - PAP2 superfamily
HGHNDNDD_00374 0.0 pbp5 - - M - - - Transglycosylase
HGHNDNDD_00375 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGHNDNDD_00376 0.0 - - - S - - - Calcineurin-like phosphoesterase
HGHNDNDD_00378 6.61e-195 - - - K - - - FCD
HGHNDNDD_00379 5.05e-310 - - - P ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_00380 0.0 neu 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
HGHNDNDD_00381 5.3e-18 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HGHNDNDD_00382 2.49e-188 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHNDNDD_00383 1.29e-231 nanA 4.1.3.3, 4.3.3.7 - EM ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
HGHNDNDD_00384 1.61e-186 oppF - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00385 0.0 oppCD2 - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HGHNDNDD_00386 2.11e-204 oppB6 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00387 0.0 oppA7 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HGHNDNDD_00388 5.17e-204 - 3.5.1.106 - I ko:K15357 ko00760,ko01120,map00760,map01120 ko00000,ko00001,ko00002,ko01000 carboxylic ester hydrolase activity
HGHNDNDD_00389 9.84e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HGHNDNDD_00390 9.73e-230 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_00391 3.65e-222 - - - L - - - Domain of unknown function (DUF4862)
HGHNDNDD_00392 1.64e-143 - - - - - - - -
HGHNDNDD_00393 3.61e-267 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGHNDNDD_00394 6.76e-125 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HGHNDNDD_00395 6.3e-174 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HGHNDNDD_00396 2.12e-81 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HGHNDNDD_00397 9.15e-135 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HGHNDNDD_00398 2.39e-85 - - - V - - - Abi-like protein
HGHNDNDD_00399 2.64e-268 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGHNDNDD_00400 9.94e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGHNDNDD_00401 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
HGHNDNDD_00402 2.69e-125 - - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00403 1.89e-275 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
HGHNDNDD_00404 3.01e-70 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
HGHNDNDD_00405 2.92e-75 - - - U - - - TadE-like protein
HGHNDNDD_00406 3.68e-55 - - - S - - - Protein of unknown function (DUF4244)
HGHNDNDD_00407 1.89e-148 - - - NU - - - Type II secretion system (T2SS), protein F
HGHNDNDD_00408 7.27e-95 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
HGHNDNDD_00409 3.09e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
HGHNDNDD_00410 7.5e-159 - - - D - - - bacterial-type flagellum organization
HGHNDNDD_00411 1.82e-171 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HGHNDNDD_00412 5.27e-162 - - - S - - - HAD hydrolase, family IA, variant 3
HGHNDNDD_00413 1.86e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HGHNDNDD_00414 3.37e-143 - - - C - - - Acyl-CoA reductase (LuxC)
HGHNDNDD_00415 5.43e-21 - - - F - - - Psort location CytoplasmicMembrane, score 10.00
HGHNDNDD_00416 5.76e-134 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
HGHNDNDD_00417 7.02e-224 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
HGHNDNDD_00418 2.49e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGHNDNDD_00419 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HGHNDNDD_00420 0.0 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
HGHNDNDD_00421 1.6e-247 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_00422 1.89e-186 traX - - S - - - TraX protein
HGHNDNDD_00423 5.22e-229 - - - S ko:K07025 - ko00000 HAD-hyrolase-like
HGHNDNDD_00424 0.0 apuB 3.2.1.41, 3.2.1.68 CBM48,GH13 G ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HGHNDNDD_00425 7.8e-208 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00426 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00427 4.66e-297 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00428 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HGHNDNDD_00429 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HGHNDNDD_00430 7.92e-221 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGHNDNDD_00431 0.0 - - - M - - - domain protein
HGHNDNDD_00432 0.0 - - - M - - - cell wall anchor domain protein
HGHNDNDD_00434 1.84e-238 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_00435 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HGHNDNDD_00436 2.36e-245 - - - K - - - Transcriptional regulator
HGHNDNDD_00437 7.47e-186 - - - S - - - Psort location Cytoplasmic, score
HGHNDNDD_00438 1.02e-259 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGHNDNDD_00439 0.0 bglA 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
HGHNDNDD_00440 2.17e-216 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00441 1.79e-267 - - - P ko:K10189,ko:K10241 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00442 0.0 - - - G ko:K10240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00443 7.83e-240 - - - K - - - Periplasmic binding protein domain
HGHNDNDD_00444 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGHNDNDD_00445 0.0 - - - EGP - - - Sugar (and other) transporter
HGHNDNDD_00446 2.29e-231 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00447 0.0 scrT - - G - - - Transporter major facilitator family protein
HGHNDNDD_00448 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
HGHNDNDD_00449 8.83e-170 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00450 2.16e-46 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00451 2.11e-80 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHNDNDD_00452 1.81e-198 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHNDNDD_00453 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HGHNDNDD_00454 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGHNDNDD_00455 3.65e-251 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HGHNDNDD_00456 2.36e-218 - - - EG - - - EamA-like transporter family
HGHNDNDD_00458 1.94e-218 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HGHNDNDD_00459 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HGHNDNDD_00460 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HGHNDNDD_00461 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
HGHNDNDD_00462 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGHNDNDD_00464 3.51e-191 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HGHNDNDD_00465 8.66e-70 - - - S - - - Putative heavy-metal-binding
HGHNDNDD_00466 4.71e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HGHNDNDD_00467 0.0 - - - KL - - - Domain of unknown function (DUF3427)
HGHNDNDD_00468 3.28e-209 - - - M - - - Glycosyltransferase like family 2
HGHNDNDD_00469 2.29e-253 - - - S - - - Fic/DOC family
HGHNDNDD_00470 7.13e-169 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
HGHNDNDD_00471 2.04e-253 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHNDNDD_00472 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
HGHNDNDD_00473 0.0 - - - S - - - Putative esterase
HGHNDNDD_00474 1.28e-28 - - - - - - - -
HGHNDNDD_00475 3.13e-226 - - - EG - - - EamA-like transporter family
HGHNDNDD_00476 2.86e-118 - - - O - - - Hsp20/alpha crystallin family
HGHNDNDD_00477 1.08e-270 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
HGHNDNDD_00478 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
HGHNDNDD_00479 3.54e-165 fhaA - - T - - - Protein of unknown function (DUF2662)
HGHNDNDD_00480 1.09e-105 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HGHNDNDD_00481 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
HGHNDNDD_00482 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HGHNDNDD_00483 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HGHNDNDD_00484 1.54e-221 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HGHNDNDD_00485 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HGHNDNDD_00486 1.11e-154 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
HGHNDNDD_00487 6.53e-291 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGHNDNDD_00488 4.26e-160 - - - S - - - Bacterial protein of unknown function (DUF881)
HGHNDNDD_00489 2.41e-101 crgA - - D - - - Involved in cell division
HGHNDNDD_00490 8.43e-179 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HGHNDNDD_00491 1.46e-47 - - - - - - - -
HGHNDNDD_00492 7.83e-195 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGHNDNDD_00493 1.59e-221 - - - L - - - Transposase, Mutator family
HGHNDNDD_00494 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HGHNDNDD_00495 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
HGHNDNDD_00496 2.63e-208 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HGHNDNDD_00497 3.53e-265 - - - I - - - Diacylglycerol kinase catalytic domain
HGHNDNDD_00498 7.57e-308 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGHNDNDD_00500 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00501 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00502 2.35e-216 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00503 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HGHNDNDD_00504 4.68e-259 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
HGHNDNDD_00505 4.59e-226 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HGHNDNDD_00506 2.47e-153 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_00507 1.35e-299 tcsS3 - - KT - - - PspC domain
HGHNDNDD_00508 0.0 pspC - - KT - - - PspC domain
HGHNDNDD_00509 2.12e-102 - - - - - - - -
HGHNDNDD_00510 0.0 - - - S ko:K06889 - ko00000 alpha beta
HGHNDNDD_00511 1.83e-142 - - - S - - - Protein of unknown function (DUF4125)
HGHNDNDD_00512 0.0 - - - S - - - Domain of unknown function (DUF4037)
HGHNDNDD_00513 6.61e-277 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
HGHNDNDD_00515 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HGHNDNDD_00516 2.77e-222 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HGHNDNDD_00517 3.9e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHNDNDD_00518 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HGHNDNDD_00519 1.02e-235 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HGHNDNDD_00520 2.3e-44 - - - - - - - -
HGHNDNDD_00521 1.6e-268 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGHNDNDD_00522 8.48e-216 - - - S - - - CHAP domain
HGHNDNDD_00523 5.28e-141 - - - M - - - NlpC/P60 family
HGHNDNDD_00524 1.26e-141 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HGHNDNDD_00525 4.53e-240 - - - T - - - Universal stress protein family
HGHNDNDD_00526 1.85e-95 - - - O - - - OsmC-like protein
HGHNDNDD_00527 8.56e-215 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGHNDNDD_00528 2.52e-163 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
HGHNDNDD_00529 3.01e-127 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
HGHNDNDD_00530 6.59e-15 - - - E - - - AzlC protein
HGHNDNDD_00531 3.41e-143 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00532 5.93e-265 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HGHNDNDD_00533 2.94e-287 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00534 7.34e-12 - - - L - - - HTH-like domain
HGHNDNDD_00535 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
HGHNDNDD_00536 6.1e-45 - - - U ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00537 2.49e-276 - - - GK - - - ROK family
HGHNDNDD_00538 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00539 1.65e-27 - - - L - - - Helix-turn-helix domain
HGHNDNDD_00540 3.05e-250 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 GHKL domain
HGHNDNDD_00541 2.58e-147 - - - K - - - Transcriptional regulatory protein, C terminal
HGHNDNDD_00542 1.71e-78 - - - - - - - -
HGHNDNDD_00543 2.21e-136 - - - - - - - -
HGHNDNDD_00544 3.39e-233 - - - V - - - Putative peptidoglycan binding domain
HGHNDNDD_00545 9.09e-152 - - - V - - - ABC transporter
HGHNDNDD_00546 2.6e-227 - - - - - - - -
HGHNDNDD_00547 3.42e-235 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HGHNDNDD_00548 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_00549 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HGHNDNDD_00550 6.11e-19 - - - L - - - Phage integrase family
HGHNDNDD_00552 1.93e-212 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGHNDNDD_00555 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
HGHNDNDD_00556 1.73e-270 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
HGHNDNDD_00557 1.82e-225 - - - M - - - Glycosyltransferase like family 2
HGHNDNDD_00558 0.0 - - - S - - - AI-2E family transporter
HGHNDNDD_00559 5.88e-297 - - - M - - - Glycosyl transferase family 21
HGHNDNDD_00560 3.45e-244 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00561 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HGHNDNDD_00562 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
HGHNDNDD_00563 1.78e-263 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGHNDNDD_00564 2.66e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHNDNDD_00565 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGHNDNDD_00566 1.9e-153 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HGHNDNDD_00567 1.9e-198 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGHNDNDD_00568 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGHNDNDD_00569 2.23e-119 - - - S - - - Protein of unknown function (DUF3180)
HGHNDNDD_00570 1.42e-214 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
HGHNDNDD_00571 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
HGHNDNDD_00572 6.63e-296 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA-like C-terminal domain
HGHNDNDD_00573 4.16e-51 - - - K - - - Helix-turn-helix XRE-family like proteins
HGHNDNDD_00574 1.11e-36 - - - K ko:K10947 - ko00000,ko03000 transcriptional regulator
HGHNDNDD_00577 0.0 - - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_00579 2.28e-223 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_00580 1.49e-111 - - - K - - - Winged helix DNA-binding domain
HGHNDNDD_00581 2.2e-19 - - - U ko:K08168,ko:K18926 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
HGHNDNDD_00582 1.93e-207 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
HGHNDNDD_00583 4.33e-95 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGHNDNDD_00584 3.41e-187 - - - - - - - -
HGHNDNDD_00585 5.32e-94 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
HGHNDNDD_00587 6.44e-49 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HGHNDNDD_00588 1.22e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGHNDNDD_00589 1.86e-211 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGHNDNDD_00590 4.61e-272 - - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HGHNDNDD_00591 1.08e-196 - - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGHNDNDD_00592 2.52e-240 - - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGHNDNDD_00593 6.71e-206 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HGHNDNDD_00594 4.8e-159 livF - - E ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00595 1.69e-152 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
HGHNDNDD_00596 1.44e-276 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
HGHNDNDD_00597 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HGHNDNDD_00598 3.86e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HGHNDNDD_00599 0.0 - - - L - - - PIF1-like helicase
HGHNDNDD_00600 5.64e-44 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
HGHNDNDD_00601 1.5e-48 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
HGHNDNDD_00602 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGHNDNDD_00603 3.81e-151 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
HGHNDNDD_00604 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
HGHNDNDD_00605 2.91e-199 - - - S - - - Short repeat of unknown function (DUF308)
HGHNDNDD_00606 1.25e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HGHNDNDD_00607 9.67e-317 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
HGHNDNDD_00608 1.24e-218 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HGHNDNDD_00609 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_00610 2.05e-127 - - - K - - - Acetyltransferase (GNAT) domain
HGHNDNDD_00611 5.04e-114 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HGHNDNDD_00612 5.03e-256 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HGHNDNDD_00613 3.68e-298 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
HGHNDNDD_00614 5.87e-229 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HGHNDNDD_00615 1.21e-268 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
HGHNDNDD_00617 1.28e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HGHNDNDD_00618 8.52e-91 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGHNDNDD_00619 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HGHNDNDD_00620 1.61e-116 ywrO - - S - - - Flavodoxin-like fold
HGHNDNDD_00621 8.78e-54 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHNDNDD_00622 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHNDNDD_00623 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
HGHNDNDD_00624 2.69e-173 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHNDNDD_00625 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
HGHNDNDD_00626 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
HGHNDNDD_00627 4.16e-167 - - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00628 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
HGHNDNDD_00629 4.52e-10 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
HGHNDNDD_00630 1.18e-60 - - - S - - - Nucleotidyltransferase domain
HGHNDNDD_00631 2.1e-90 - - - S - - - Nucleotidyltransferase substrate binding protein like
HGHNDNDD_00632 4.52e-307 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
HGHNDNDD_00633 5.31e-236 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HGHNDNDD_00634 3e-109 - - - K - - - MarR family
HGHNDNDD_00635 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00636 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HGHNDNDD_00637 1.06e-160 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00638 1.58e-56 - - - K - - - acetyltransferase
HGHNDNDD_00639 4.64e-130 rihA - - F ko:K01250,ko:K12700 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HGHNDNDD_00640 8.07e-201 - - - C ko:K03326 - ko00000,ko02000 C4-dicarboxylate anaerobic carrier
HGHNDNDD_00641 6.99e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHNDNDD_00642 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGHNDNDD_00643 1.24e-95 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
HGHNDNDD_00644 3.39e-226 - - - L - - - Phage integrase family
HGHNDNDD_00645 4.73e-40 - - - - - - - -
HGHNDNDD_00646 2.52e-202 - - - L - - - Domain of unknown function (DUF4357)
HGHNDNDD_00647 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
HGHNDNDD_00650 0.0 - - - K - - - Putative DNA-binding domain
HGHNDNDD_00651 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HGHNDNDD_00653 2.24e-190 - - - G - - - Fic/DOC family
HGHNDNDD_00654 1.37e-290 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGHNDNDD_00655 5.45e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGHNDNDD_00656 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HGHNDNDD_00657 1.35e-237 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGHNDNDD_00658 5.9e-169 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGHNDNDD_00659 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGHNDNDD_00660 1.43e-154 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
HGHNDNDD_00661 1.69e-162 - - - S - - - SNARE associated Golgi protein
HGHNDNDD_00662 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
HGHNDNDD_00663 1.39e-173 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGHNDNDD_00664 0.0 - - - K ko:K02538,ko:K03483,ko:K03491 - ko00000,ko03000 PRD domain
HGHNDNDD_00665 5.42e-95 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHNDNDD_00666 1.1e-103 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHNDNDD_00667 2.2e-62 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HGHNDNDD_00668 9.78e-228 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
HGHNDNDD_00669 4.32e-173 - - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
HGHNDNDD_00670 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
HGHNDNDD_00671 4.8e-224 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
HGHNDNDD_00672 2.31e-13 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HGHNDNDD_00673 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HGHNDNDD_00674 3.31e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
HGHNDNDD_00675 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
HGHNDNDD_00676 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
HGHNDNDD_00677 4.3e-143 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HGHNDNDD_00678 0.0 - - - S - - - PGAP1-like protein
HGHNDNDD_00679 8.97e-71 - - - - - - - -
HGHNDNDD_00680 1.04e-213 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HGHNDNDD_00681 1.03e-239 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HGHNDNDD_00682 3.26e-119 - - - - - - - -
HGHNDNDD_00683 3.97e-210 - - - S - - - Protein of unknown function DUF58
HGHNDNDD_00684 3.09e-245 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HGHNDNDD_00685 3.3e-168 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGHNDNDD_00686 3.61e-121 - - - S - - - LytR cell envelope-related transcriptional attenuator
HGHNDNDD_00687 1.54e-51 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HGHNDNDD_00688 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGHNDNDD_00689 6.57e-54 - - - S - - - Proteins of 100 residues with WXG
HGHNDNDD_00690 2.67e-148 - - - - - - - -
HGHNDNDD_00691 2.48e-170 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
HGHNDNDD_00692 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HGHNDNDD_00693 1.75e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HGHNDNDD_00694 8.78e-240 - - - S - - - Protein of unknown function (DUF3027)
HGHNDNDD_00695 6.61e-230 uspA - - T - - - Belongs to the universal stress protein A family
HGHNDNDD_00696 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
HGHNDNDD_00697 5.94e-16 - - - K - - - AraC-like ligand binding domain
HGHNDNDD_00698 5.71e-178 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
HGHNDNDD_00699 8.34e-68 - - - I - - - Hydrolase, alpha beta domain protein
HGHNDNDD_00700 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
HGHNDNDD_00701 0.0 - - - S - - - Domain of Unknown Function (DUF349)
HGHNDNDD_00702 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
HGHNDNDD_00703 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGHNDNDD_00704 3.53e-129 - - - S - - - Aminoacyl-tRNA editing domain
HGHNDNDD_00705 2.6e-195 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
HGHNDNDD_00706 2.06e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGHNDNDD_00707 1.21e-143 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00708 7.37e-252 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00709 0.0 - - - I - - - PAP2 superfamily
HGHNDNDD_00710 1.13e-145 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HGHNDNDD_00711 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HGHNDNDD_00712 1.47e-254 - - - S - - - Polyphosphate kinase 2 (PPK2)
HGHNDNDD_00713 0.0 - - - L - - - DEAD DEAH box helicase
HGHNDNDD_00714 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
HGHNDNDD_00715 2.53e-14 mtrA - - KT ko:K07670 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HGHNDNDD_00716 2.13e-40 mtrB 2.7.13.3 - T ko:K07636,ko:K07654 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGHNDNDD_00717 0.0 - - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_00718 2.33e-238 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HGHNDNDD_00719 3.36e-69 - - - - - - - -
HGHNDNDD_00720 1.66e-70 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HGHNDNDD_00721 6.38e-61 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
HGHNDNDD_00722 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00723 3.87e-132 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGHNDNDD_00724 2.57e-251 - - - S - - - Glycosyltransferase, group 2 family protein
HGHNDNDD_00725 4.87e-188 - - - C - - - Putative TM nitroreductase
HGHNDNDD_00726 1.56e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_00727 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HGHNDNDD_00728 1.8e-306 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
HGHNDNDD_00729 8.6e-250 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00730 0.0 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
HGHNDNDD_00731 8.19e-244 - - - - - - - -
HGHNDNDD_00732 9.54e-22 - - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_00733 2.12e-125 - - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_00734 4.58e-294 - - - T - - - Histidine kinase
HGHNDNDD_00735 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
HGHNDNDD_00736 1.64e-81 - - - S - - - Thiamine-binding protein
HGHNDNDD_00737 2.14e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HGHNDNDD_00738 4.08e-290 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
HGHNDNDD_00739 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGHNDNDD_00740 1.17e-199 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGHNDNDD_00741 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
HGHNDNDD_00742 0.0 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHNDNDD_00743 7.1e-274 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGHNDNDD_00744 1.42e-91 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGHNDNDD_00745 3.44e-60 - - - S ko:K02221 - ko00000,ko02044 YGGT family
HGHNDNDD_00746 1.28e-88 - - - V - - - DivIVA protein
HGHNDNDD_00747 4.73e-114 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGHNDNDD_00748 1.44e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HGHNDNDD_00749 2.13e-256 - - - K - - - WYL domain
HGHNDNDD_00750 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
HGHNDNDD_00752 1.79e-213 dkgV - - C - - - Aldo/keto reductase family
HGHNDNDD_00753 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
HGHNDNDD_00754 2.57e-251 - - - S - - - Protein conserved in bacteria
HGHNDNDD_00755 2.12e-97 - - - K - - - Transcriptional regulator
HGHNDNDD_00756 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGHNDNDD_00757 2.23e-241 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHNDNDD_00758 4.47e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGHNDNDD_00759 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
HGHNDNDD_00760 1.32e-129 - - - - - - - -
HGHNDNDD_00761 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGHNDNDD_00762 2.39e-277 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
HGHNDNDD_00763 1.29e-278 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGHNDNDD_00764 8.26e-106 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGHNDNDD_00765 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGHNDNDD_00766 1.3e-242 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HGHNDNDD_00767 1.37e-162 - - - - - - - -
HGHNDNDD_00768 1.08e-91 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00770 6.18e-196 - - - E - - - Transglutaminase/protease-like homologues
HGHNDNDD_00771 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
HGHNDNDD_00772 1.27e-218 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGHNDNDD_00773 2.36e-90 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HGHNDNDD_00774 8.1e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHNDNDD_00775 2.99e-85 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGHNDNDD_00776 2e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGHNDNDD_00777 1.47e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HGHNDNDD_00778 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGHNDNDD_00779 3e-127 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGHNDNDD_00780 2.8e-316 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGHNDNDD_00781 1.07e-98 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HGHNDNDD_00782 4.64e-36 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
HGHNDNDD_00783 2.25e-129 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGHNDNDD_00784 3.09e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGHNDNDD_00785 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGHNDNDD_00786 3.17e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGHNDNDD_00787 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHNDNDD_00788 3.93e-134 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGHNDNDD_00789 5.4e-69 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGHNDNDD_00790 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGHNDNDD_00791 1.58e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGHNDNDD_00792 1.97e-49 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HGHNDNDD_00793 3.85e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGHNDNDD_00794 1.85e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGHNDNDD_00795 1.09e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGHNDNDD_00796 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGHNDNDD_00797 3.85e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGHNDNDD_00798 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGHNDNDD_00799 9.78e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HGHNDNDD_00800 1.11e-149 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGHNDNDD_00801 9.35e-68 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HGHNDNDD_00802 1.15e-173 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HGHNDNDD_00803 8.47e-184 - - - S - - - YwiC-like protein
HGHNDNDD_00804 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HGHNDNDD_00805 2.64e-217 - - - K - - - helix_turn_helix, arabinose operon control protein
HGHNDNDD_00806 2.76e-246 - 1.1.1.9 - C ko:K05351 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HGHNDNDD_00807 1.73e-248 csbX - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_00808 9.79e-275 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HGHNDNDD_00809 2.66e-97 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGHNDNDD_00810 3.54e-295 csbX - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_00811 2.47e-227 - 1.1.1.1, 1.1.1.287, 1.6.5.5 - C ko:K00001,ko:K00344,ko:K17818 ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HGHNDNDD_00812 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HGHNDNDD_00813 9.6e-106 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HGHNDNDD_00814 5.33e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGHNDNDD_00815 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HGHNDNDD_00816 9.47e-152 - - - - - - - -
HGHNDNDD_00817 3.98e-143 yigZ - - S - - - Uncharacterized protein family UPF0029
HGHNDNDD_00818 8.23e-234 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHNDNDD_00819 1.44e-272 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
HGHNDNDD_00820 1.16e-311 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
HGHNDNDD_00821 5.08e-205 - - - U ko:K02026,ko:K10190 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00822 4.88e-208 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00823 6.32e-311 - - - G ko:K02027,ko:K10227 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00824 6.09e-276 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_00825 2.08e-30 - - - - - - - -
HGHNDNDD_00827 7.18e-81 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
HGHNDNDD_00828 2.87e-28 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
HGHNDNDD_00829 1.17e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGHNDNDD_00830 3.3e-281 dapC - - E - - - Aminotransferase class I and II
HGHNDNDD_00831 4.51e-79 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
HGHNDNDD_00832 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
HGHNDNDD_00833 5.09e-282 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HGHNDNDD_00834 1.03e-34 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
HGHNDNDD_00838 1.73e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGHNDNDD_00839 2.96e-182 - - - - - - - -
HGHNDNDD_00840 2.1e-112 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HGHNDNDD_00841 7.23e-79 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
HGHNDNDD_00842 6.24e-43 - - - S - - - Putative regulatory protein
HGHNDNDD_00843 9.74e-138 - - - NO - - - SAF
HGHNDNDD_00844 2.05e-33 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
HGHNDNDD_00845 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
HGHNDNDD_00846 9.04e-273 - - - T - - - Forkhead associated domain
HGHNDNDD_00847 1.06e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGHNDNDD_00848 2.41e-113 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGHNDNDD_00849 2.8e-186 - - - S - - - alpha beta
HGHNDNDD_00850 0.0 - - - S ko:K06901 - ko00000,ko02000 Permease family
HGHNDNDD_00851 4.51e-190 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGHNDNDD_00852 1.86e-221 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HGHNDNDD_00853 2.71e-211 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HGHNDNDD_00854 2.32e-260 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
HGHNDNDD_00855 1.5e-182 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HGHNDNDD_00856 6.87e-278 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HGHNDNDD_00857 7.16e-308 - - - EGP - - - Sugar (and other) transporter
HGHNDNDD_00858 2.11e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGHNDNDD_00859 2.22e-298 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGHNDNDD_00860 3.98e-278 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGHNDNDD_00861 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HGHNDNDD_00862 1.23e-120 - - - D - - - nuclear chromosome segregation
HGHNDNDD_00863 5.05e-161 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGHNDNDD_00864 3.28e-194 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HGHNDNDD_00865 6.09e-254 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
HGHNDNDD_00866 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
HGHNDNDD_00867 6.83e-225 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HGHNDNDD_00868 2.86e-133 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
HGHNDNDD_00869 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
HGHNDNDD_00870 1.05e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HGHNDNDD_00871 3.63e-247 - - - G - - - pfkB family carbohydrate kinase
HGHNDNDD_00872 9.88e-300 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HGHNDNDD_00873 5.51e-242 - - - K - - - Helix-turn-helix XRE-family like proteins
HGHNDNDD_00874 3.06e-82 - - - S - - - Alpha/beta hydrolase family
HGHNDNDD_00878 2.03e-58 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HGHNDNDD_00880 0.0 pccB - - I - - - Carboxyl transferase domain
HGHNDNDD_00881 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HGHNDNDD_00883 4.78e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HGHNDNDD_00884 6.41e-210 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HGHNDNDD_00885 0.0 - - - - - - - -
HGHNDNDD_00886 3.74e-211 - - - QT - - - PucR C-terminal helix-turn-helix domain
HGHNDNDD_00887 1.01e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGHNDNDD_00888 7.11e-96 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGHNDNDD_00889 1.43e-169 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HGHNDNDD_00890 2.77e-41 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGHNDNDD_00892 3.24e-291 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
HGHNDNDD_00893 2.27e-287 - - - G - - - polysaccharide deacetylase
HGHNDNDD_00894 4.53e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGHNDNDD_00895 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGHNDNDD_00896 1.44e-51 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
HGHNDNDD_00897 1.01e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HGHNDNDD_00898 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
HGHNDNDD_00899 2.1e-294 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HGHNDNDD_00900 6.44e-213 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HGHNDNDD_00901 6.01e-214 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
HGHNDNDD_00902 1.15e-190 - - - S ko:K07046 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Amidohydrolase
HGHNDNDD_00903 1.93e-270 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HGHNDNDD_00904 5.27e-191 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
HGHNDNDD_00905 0.0 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
HGHNDNDD_00906 4.75e-245 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
HGHNDNDD_00907 1.24e-281 - - - V - - - Efflux ABC transporter, permease protein
HGHNDNDD_00908 1.67e-164 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00909 2.44e-38 - - - S - - - Protein of unknown function (DUF1778)
HGHNDNDD_00910 3.74e-115 - - - K - - - Acetyltransferase (GNAT) family
HGHNDNDD_00911 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
HGHNDNDD_00912 8.65e-234 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGHNDNDD_00913 1.31e-302 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HGHNDNDD_00914 1.82e-295 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HGHNDNDD_00915 1.09e-72 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHNDNDD_00916 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGHNDNDD_00917 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HGHNDNDD_00918 8.34e-165 - - - K - - - Bacterial regulatory proteins, tetR family
HGHNDNDD_00919 2.22e-279 - - - G - - - Transmembrane secretion effector
HGHNDNDD_00920 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHNDNDD_00921 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
HGHNDNDD_00922 2.15e-200 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HGHNDNDD_00923 3.01e-155 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00924 1.8e-177 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00925 1.44e-133 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HGHNDNDD_00926 4.6e-169 - - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_00927 1.02e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
HGHNDNDD_00928 1e-39 - - - T - - - Histidine kinase
HGHNDNDD_00929 2.22e-169 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGHNDNDD_00930 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGHNDNDD_00931 3.37e-181 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
HGHNDNDD_00932 0.0 - - - S - - - Calcineurin-like phosphoesterase
HGHNDNDD_00933 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGHNDNDD_00934 1.77e-316 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
HGHNDNDD_00935 1.2e-176 - - - - - - - -
HGHNDNDD_00936 0.0 - - - G - - - N-terminal domain of (some) glycogen debranching enzymes
HGHNDNDD_00937 1.73e-177 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00938 1.3e-267 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00939 3.39e-264 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_00940 3.44e-164 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_00941 9.47e-151 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGHNDNDD_00942 1.05e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGHNDNDD_00943 8.96e-275 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HGHNDNDD_00944 1.43e-278 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HGHNDNDD_00946 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHNDNDD_00947 6.65e-208 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
HGHNDNDD_00948 8.47e-202 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
HGHNDNDD_00949 5.17e-162 - - - S - - - Domain of unknown function (DUF4190)
HGHNDNDD_00950 2.49e-209 - - - - - - - -
HGHNDNDD_00951 3.97e-301 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HGHNDNDD_00952 1.83e-257 - - - M - - - Glycosyltransferase like family 2
HGHNDNDD_00953 7.54e-229 - - - S - - - Predicted membrane protein (DUF2142)
HGHNDNDD_00954 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
HGHNDNDD_00955 0.0 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
HGHNDNDD_00956 2.23e-206 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00957 1.16e-152 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HGHNDNDD_00958 1.53e-214 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGHNDNDD_00959 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGHNDNDD_00960 3.56e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGHNDNDD_00961 0.0 - - - - - - - -
HGHNDNDD_00962 1.3e-209 - - - M - - - Glycosyl transferase family 2
HGHNDNDD_00963 3.74e-39 - - - M - - - nuclease
HGHNDNDD_00964 7.76e-99 - - - M - - - L,D-transpeptidase catalytic domain
HGHNDNDD_00965 1.7e-228 - - - M - - - Glycosyl hydrolases family 25
HGHNDNDD_00966 2.44e-304 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
HGHNDNDD_00967 0.0 - - - V - - - ABC transporter permease
HGHNDNDD_00968 9.32e-244 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGHNDNDD_00969 4.49e-183 - - - T ko:K06950 - ko00000 HD domain
HGHNDNDD_00970 2.87e-204 - - - S - - - Glutamine amidotransferase domain
HGHNDNDD_00971 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HGHNDNDD_00972 3.31e-238 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
HGHNDNDD_00973 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HGHNDNDD_00974 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HGHNDNDD_00975 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_00976 9.96e-54 - - - G - - - Glycosyl hydrolases family 43
HGHNDNDD_00977 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HGHNDNDD_00978 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGHNDNDD_00979 1.74e-226 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HGHNDNDD_00980 8.66e-229 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_00981 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HGHNDNDD_00982 1.73e-63 - - - - - - - -
HGHNDNDD_00983 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGHNDNDD_00984 1.26e-154 - - - - - - - -
HGHNDNDD_00985 5.26e-236 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGHNDNDD_00987 0.0 - - - G - - - MFS/sugar transport protein
HGHNDNDD_00988 1.33e-227 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHNDNDD_00989 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
HGHNDNDD_00990 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_00991 8.11e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGHNDNDD_00992 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
HGHNDNDD_00993 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_00994 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGHNDNDD_00995 7.06e-132 - - - K - - - Transcriptional regulator C-terminal region
HGHNDNDD_00996 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
HGHNDNDD_00997 8.13e-137 - - - S - - - Protein of unknown function, DUF624
HGHNDNDD_00998 4.49e-196 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HGHNDNDD_00999 3.3e-200 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01000 2.13e-223 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_01001 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01002 1.29e-132 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HGHNDNDD_01003 6.43e-79 - - - S - - - Protein of unknown function (DUF4235)
HGHNDNDD_01004 1.1e-158 nfrA - - C - - - Nitroreductase family
HGHNDNDD_01005 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HGHNDNDD_01006 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
HGHNDNDD_01007 2.58e-54 - - - - - - - -
HGHNDNDD_01008 3.81e-228 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
HGHNDNDD_01009 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGHNDNDD_01010 2.25e-136 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGHNDNDD_01011 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HGHNDNDD_01012 1.53e-209 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGHNDNDD_01013 2.41e-260 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HGHNDNDD_01014 5.24e-206 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01015 6.37e-174 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HGHNDNDD_01016 5.08e-114 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HGHNDNDD_01017 2.16e-130 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
HGHNDNDD_01018 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGHNDNDD_01019 1.23e-164 cseB - - T - - - Response regulator receiver domain protein
HGHNDNDD_01020 1.43e-249 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HGHNDNDD_01021 1.51e-157 pyrE_1 - - S - - - Phosphoribosyl transferase domain
HGHNDNDD_01022 2.4e-189 - - - T - - - Eukaryotic phosphomannomutase
HGHNDNDD_01023 2.13e-101 - - - S - - - Zincin-like metallopeptidase
HGHNDNDD_01024 0.0 - - - - - - - -
HGHNDNDD_01025 0.0 - - - S - - - Glycosyl transferase, family 2
HGHNDNDD_01026 2.06e-74 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HGHNDNDD_01027 1.18e-292 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
HGHNDNDD_01028 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
HGHNDNDD_01029 8.13e-62 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HGHNDNDD_01030 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HGHNDNDD_01031 3.56e-194 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
HGHNDNDD_01032 7.1e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHNDNDD_01033 8.17e-98 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
HGHNDNDD_01034 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
HGHNDNDD_01035 1.65e-121 - - - - - - - -
HGHNDNDD_01037 9.07e-234 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HGHNDNDD_01038 1.13e-132 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
HGHNDNDD_01039 1.89e-113 - - - D - - - Septum formation initiator
HGHNDNDD_01040 7.13e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHNDNDD_01041 7.72e-229 - - - C - - - Aldo/keto reductase family
HGHNDNDD_01042 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGHNDNDD_01043 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGHNDNDD_01044 1.3e-118 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HGHNDNDD_01045 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
HGHNDNDD_01046 1.05e-30 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HGHNDNDD_01047 2.08e-115 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HGHNDNDD_01048 1.1e-177 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGHNDNDD_01049 2.19e-125 - - - - - - - -
HGHNDNDD_01050 9.06e-298 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGHNDNDD_01051 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
HGHNDNDD_01052 1.36e-250 - - - S - - - Protein of unknown function (DUF1648)
HGHNDNDD_01053 1.07e-93 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HGHNDNDD_01054 3.61e-37 pacL2 3.6.3.8 - P ko:K01537,ko:K12955 - ko00000,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HGHNDNDD_01055 6.59e-131 - - - S - - - ABC-2 family transporter protein
HGHNDNDD_01056 5.55e-155 - - - S - - - ABC-2 family transporter protein
HGHNDNDD_01057 1.43e-221 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01058 3.46e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HGHNDNDD_01059 3.33e-43 - - - J - - - Acetyltransferase (GNAT) domain
HGHNDNDD_01060 9.65e-15 - - - J - - - Acetyltransferase (GNAT) domain
HGHNDNDD_01061 3.85e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
HGHNDNDD_01062 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HGHNDNDD_01063 4.51e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGHNDNDD_01065 2.27e-90 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
HGHNDNDD_01066 4.97e-147 - - - - - - - -
HGHNDNDD_01067 6.08e-178 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HGHNDNDD_01069 5.65e-256 - - - G - - - Haloacid dehalogenase-like hydrolase
HGHNDNDD_01070 9.25e-302 - - - L - - - Tetratricopeptide repeat
HGHNDNDD_01071 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGHNDNDD_01072 8.81e-41 - - - S - - - Protein of unknown function (DUF975)
HGHNDNDD_01073 3.36e-67 - - - S - - - Protein of unknown function (DUF975)
HGHNDNDD_01074 7.1e-62 - - - S - - - Protein of unknown function (DUF975)
HGHNDNDD_01075 1.35e-164 - - - S - - - Putative ABC-transporter type IV
HGHNDNDD_01076 4.67e-122 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHNDNDD_01077 2.24e-65 - - - P - - - Rhodanese Homology Domain
HGHNDNDD_01078 2.54e-176 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HGHNDNDD_01079 1.02e-201 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HGHNDNDD_01080 3.55e-39 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
HGHNDNDD_01081 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HGHNDNDD_01082 1.2e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGHNDNDD_01083 2.51e-109 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HGHNDNDD_01084 7.19e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGHNDNDD_01085 6.6e-313 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HGHNDNDD_01086 3.39e-226 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HGHNDNDD_01087 9.67e-272 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGHNDNDD_01088 2.32e-259 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGHNDNDD_01089 2.39e-124 - - - - - - - -
HGHNDNDD_01090 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
HGHNDNDD_01091 2.51e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGHNDNDD_01092 8.12e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHNDNDD_01093 1.62e-205 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HGHNDNDD_01094 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01095 4.38e-140 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HGHNDNDD_01096 0.0 argE - - E - - - Peptidase dimerisation domain
HGHNDNDD_01097 4.43e-130 - - - S - - - Protein of unknown function (DUF3043)
HGHNDNDD_01098 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGHNDNDD_01099 5.87e-182 - - - S - - - Domain of unknown function (DUF4191)
HGHNDNDD_01100 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HGHNDNDD_01101 2.72e-262 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HGHNDNDD_01102 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGHNDNDD_01103 0.0 - - - S - - - Tetratricopeptide repeat
HGHNDNDD_01104 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGHNDNDD_01105 8.79e-09 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HGHNDNDD_01106 4.82e-183 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01107 4.94e-287 - - - E - - - Aminotransferase class I and II
HGHNDNDD_01108 1.25e-242 - - - P - - - NMT1/THI5 like
HGHNDNDD_01109 3.49e-173 - - - P - - - Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01110 1.58e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGHNDNDD_01111 6.84e-166 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HGHNDNDD_01112 0.0 - - - I - - - acetylesterase activity
HGHNDNDD_01113 5.4e-293 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGHNDNDD_01114 3.57e-281 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HGHNDNDD_01115 1.24e-297 - - - NU - - - Tfp pilus assembly protein FimV
HGHNDNDD_01117 2.42e-96 - - - S - - - Protein of unknown function (DUF3052)
HGHNDNDD_01118 1.74e-209 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HGHNDNDD_01119 0.0 - - - S - - - Zincin-like metallopeptidase
HGHNDNDD_01120 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGHNDNDD_01121 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
HGHNDNDD_01122 3.25e-44 - - - S - - - Protein of unknown function (DUF3107)
HGHNDNDD_01123 1.8e-215 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
HGHNDNDD_01124 1.13e-164 - - - S - - - Vitamin K epoxide reductase
HGHNDNDD_01125 1.32e-218 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HGHNDNDD_01126 5.69e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HGHNDNDD_01127 5.74e-204 - - - S - - - Patatin-like phospholipase
HGHNDNDD_01128 9.81e-72 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_01129 1.03e-169 hflK - - O - - - prohibitin homologues
HGHNDNDD_01130 1.46e-270 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HGHNDNDD_01131 3.8e-56 - - - O - - - Glutaredoxin
HGHNDNDD_01132 7.76e-299 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HGHNDNDD_01133 2.27e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HGHNDNDD_01134 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
HGHNDNDD_01136 2.06e-174 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
HGHNDNDD_01137 9.2e-136 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HGHNDNDD_01138 2.65e-217 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HGHNDNDD_01139 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HGHNDNDD_01140 6.96e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HGHNDNDD_01141 1.02e-120 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGHNDNDD_01142 6.57e-136 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGHNDNDD_01143 1.18e-160 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01144 1.03e-167 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HGHNDNDD_01145 2.4e-107 - - - M - - - L,D-transpeptidase catalytic domain
HGHNDNDD_01146 4.98e-18 - - - - - - - -
HGHNDNDD_01147 5.13e-36 - - - - - - - -
HGHNDNDD_01148 4.84e-23 - - - - - - - -
HGHNDNDD_01149 3.31e-107 - - - L - - - Transposase
HGHNDNDD_01150 3.7e-14 - 4.1.1.44 - L ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HGHNDNDD_01151 6.87e-236 - - - S ko:K07088 - ko00000 Membrane transport protein
HGHNDNDD_01152 4.51e-51 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HGHNDNDD_01153 9.35e-154 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HGHNDNDD_01154 2.12e-05 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HGHNDNDD_01155 2.2e-159 - - - L ko:K07457 - ko00000 endonuclease III
HGHNDNDD_01156 1.5e-103 - - - V - - - MatE
HGHNDNDD_01157 1.68e-185 - - - V - - - MatE
HGHNDNDD_01158 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HGHNDNDD_01159 8.43e-141 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
HGHNDNDD_01160 1.63e-306 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_01161 1.19e-11 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_01162 5.15e-247 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HGHNDNDD_01163 1.02e-98 - - - K - - - MerR family regulatory protein
HGHNDNDD_01164 6.33e-116 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHNDNDD_01165 2.66e-76 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHNDNDD_01166 1.11e-41 - - - S - - - Psort location CytoplasmicMembrane, score
HGHNDNDD_01167 1.24e-237 - - - S - - - Conserved hypothetical protein 698
HGHNDNDD_01168 1.49e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HGHNDNDD_01169 6.03e-164 tmp1 - - S - - - Domain of unknown function (DUF4391)
HGHNDNDD_01170 4.1e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGHNDNDD_01171 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGHNDNDD_01172 1.9e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGHNDNDD_01173 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGHNDNDD_01174 3.92e-247 - - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
HGHNDNDD_01176 1.74e-251 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
HGHNDNDD_01177 4.49e-279 - - - M - - - Glycosyl transferase 4-like domain
HGHNDNDD_01178 1.05e-290 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HGHNDNDD_01179 2.22e-296 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGHNDNDD_01180 4.83e-176 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HGHNDNDD_01181 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
HGHNDNDD_01182 7.19e-315 - - - I - - - alpha/beta hydrolase fold
HGHNDNDD_01183 0.0 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
HGHNDNDD_01184 1.96e-146 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
HGHNDNDD_01185 8.33e-187 - - - - - - - -
HGHNDNDD_01189 2.2e-131 nnrE - - L - - - Uracil DNA glycosylase superfamily
HGHNDNDD_01190 1.95e-19 - - - C - - - Aldo/keto reductase family
HGHNDNDD_01191 1.98e-44 - - - - - - - -
HGHNDNDD_01192 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
HGHNDNDD_01193 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGHNDNDD_01194 5.52e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HGHNDNDD_01195 6.04e-309 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HGHNDNDD_01196 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
HGHNDNDD_01197 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
HGHNDNDD_01198 2.27e-198 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HGHNDNDD_01199 1.13e-127 - - - S - - - cobalamin synthesis protein
HGHNDNDD_01200 8.31e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HGHNDNDD_01201 5.79e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
HGHNDNDD_01202 1.24e-58 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHNDNDD_01203 1.72e-45 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HGHNDNDD_01204 4.34e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
HGHNDNDD_01205 1.55e-27 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
HGHNDNDD_01206 3.5e-35 - - - P ko:K02077,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HGHNDNDD_01207 2.8e-256 - - - S ko:K07089 - ko00000 Predicted permease
HGHNDNDD_01208 1.14e-179 - - - S - - - TIGRFAM TIGR03943 family protein
HGHNDNDD_01209 4.6e-26 fur - - P ko:K03711 - ko00000,ko03000 Ferric uptake regulator family
HGHNDNDD_01210 2.31e-72 fur - - P ko:K03711 - ko00000,ko03000 Ferric uptake regulator family
HGHNDNDD_01211 9.84e-85 - - - - - - - -
HGHNDNDD_01212 4.92e-90 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGHNDNDD_01213 1.29e-33 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_01214 1.65e-97 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_01215 7.7e-95 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HGHNDNDD_01216 4.92e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGHNDNDD_01217 1.46e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGHNDNDD_01218 6.6e-230 yogA - - C - - - Zinc-binding dehydrogenase
HGHNDNDD_01219 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGHNDNDD_01220 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HGHNDNDD_01221 1.1e-256 - - - M - - - Conserved repeat domain
HGHNDNDD_01222 7.65e-183 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01223 2.56e-110 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 peptide-methionine (S)-S-oxide reductase activity
HGHNDNDD_01224 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HGHNDNDD_01225 1.98e-18 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_01226 1.71e-242 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HGHNDNDD_01227 5.45e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
HGHNDNDD_01228 4.16e-07 - - - S - - - Spermine/spermidine synthase domain
HGHNDNDD_01229 1.72e-157 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGHNDNDD_01230 2.72e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
HGHNDNDD_01231 7.76e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGHNDNDD_01232 1.24e-243 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HGHNDNDD_01233 7.02e-202 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
HGHNDNDD_01234 4.16e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HGHNDNDD_01235 2.69e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGHNDNDD_01236 2.57e-149 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGHNDNDD_01237 3.2e-204 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
HGHNDNDD_01238 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGHNDNDD_01239 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HGHNDNDD_01240 7.53e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
HGHNDNDD_01241 4.05e-303 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
HGHNDNDD_01242 4.83e-24 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
HGHNDNDD_01243 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_01244 5.21e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01245 1.2e-138 - - - K - - - Virulence activator alpha C-term
HGHNDNDD_01246 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
HGHNDNDD_01247 1.16e-100 - - - - - - - -
HGHNDNDD_01248 1.16e-240 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HGHNDNDD_01249 9.56e-243 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
HGHNDNDD_01250 2.36e-56 - - - - - - - -
HGHNDNDD_01251 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HGHNDNDD_01252 1.75e-188 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_01253 2.09e-242 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HGHNDNDD_01254 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HGHNDNDD_01255 1.39e-204 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01256 2.81e-233 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HGHNDNDD_01257 0.0 - - - EP ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HGHNDNDD_01258 4.59e-217 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
HGHNDNDD_01259 2.93e-197 - - - S - - - Protein of unknown function (DUF3710)
HGHNDNDD_01260 2.99e-174 - - - S - - - Protein of unknown function (DUF3159)
HGHNDNDD_01261 1.86e-306 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHNDNDD_01262 2.15e-124 - - - - - - - -
HGHNDNDD_01263 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HGHNDNDD_01264 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGHNDNDD_01265 2.33e-155 - - - E - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_01266 6.96e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
HGHNDNDD_01267 1.75e-206 - - - EG - - - EamA-like transporter family
HGHNDNDD_01268 6.37e-189 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
HGHNDNDD_01269 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGHNDNDD_01270 4.29e-229 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGHNDNDD_01271 1.35e-193 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HGHNDNDD_01272 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
HGHNDNDD_01273 5.72e-151 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGHNDNDD_01274 1.17e-119 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HGHNDNDD_01275 1.55e-99 - - - K - - - Helix-turn-helix XRE-family like proteins
HGHNDNDD_01276 2.07e-61 - - - S - - - Protein of unknown function (DUF3046)
HGHNDNDD_01277 5.78e-253 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGHNDNDD_01278 1.3e-132 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HGHNDNDD_01279 1.89e-149 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGHNDNDD_01280 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGHNDNDD_01281 8.85e-244 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGHNDNDD_01282 2.21e-157 - - - - - - - -
HGHNDNDD_01283 2.4e-169 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HGHNDNDD_01284 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
HGHNDNDD_01285 4.79e-251 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HGHNDNDD_01286 1.39e-145 - - - - - - - -
HGHNDNDD_01287 7.15e-248 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGHNDNDD_01288 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HGHNDNDD_01289 2.17e-285 - - - G - - - Major Facilitator Superfamily
HGHNDNDD_01290 9.99e-220 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHNDNDD_01291 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HGHNDNDD_01294 8.26e-28 - - - K - - - helix_turn_helix, arabinose operon control protein
HGHNDNDD_01295 8.31e-135 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01297 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
HGHNDNDD_01298 7.3e-299 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
HGHNDNDD_01299 1.95e-208 - - - S - - - Protein of unknown function (DUF3071)
HGHNDNDD_01300 4.95e-63 - - - S - - - Domain of unknown function (DUF4193)
HGHNDNDD_01301 4.13e-109 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HGHNDNDD_01302 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGHNDNDD_01303 4.15e-151 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGHNDNDD_01305 4.58e-82 - - - - - - - -
HGHNDNDD_01306 9.8e-14 - - - U - - - type IV secretory pathway VirB4
HGHNDNDD_01307 1.26e-34 - - - - - - - -
HGHNDNDD_01308 7.81e-24 - - - - - - - -
HGHNDNDD_01309 2.22e-278 - - - S - - - Helix-turn-helix domain
HGHNDNDD_01310 2.36e-55 - - - - - - - -
HGHNDNDD_01311 5.79e-117 - - - S - - - Transcription factor WhiB
HGHNDNDD_01312 4.8e-149 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
HGHNDNDD_01313 4.18e-42 - - - - - - - -
HGHNDNDD_01315 2.35e-50 - - - - ko:K03646 - ko00000,ko02000 -
HGHNDNDD_01316 0.0 - - - D - - - Cell surface antigen C-terminus
HGHNDNDD_01318 7.85e-290 - - - L - - - Transposase and inactivated derivatives
HGHNDNDD_01319 1.38e-143 - - - - - - - -
HGHNDNDD_01320 3.74e-206 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
HGHNDNDD_01321 1.58e-289 - - - L - - - Transposase and inactivated derivatives
HGHNDNDD_01322 3.18e-87 - - - M - - - Collagen binding domain
HGHNDNDD_01323 9.82e-54 - - - D - - - Cell surface antigen C-terminus
HGHNDNDD_01324 0.0 - - - O - - - Subtilase family
HGHNDNDD_01325 1.17e-268 - - - O - - - ATPase family associated with various cellular activities (AAA)
HGHNDNDD_01326 2.56e-190 - - - D - - - Cell surface antigen C-terminus
HGHNDNDD_01327 2.76e-186 - - - - - - - -
HGHNDNDD_01328 2.51e-83 - - - S - - - PrgI family protein
HGHNDNDD_01329 0.0 - - - U - - - type IV secretory pathway VirB4
HGHNDNDD_01330 0.0 - - - M - - - CHAP domain
HGHNDNDD_01331 4.84e-125 - - - - - - - -
HGHNDNDD_01332 5.15e-206 - - - - ko:K03646 - ko00000,ko02000 -
HGHNDNDD_01333 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
HGHNDNDD_01334 1.67e-44 - - - - - - - -
HGHNDNDD_01335 9.05e-50 - - - - - - - -
HGHNDNDD_01336 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGHNDNDD_01337 0.0 - - - - - - - -
HGHNDNDD_01338 7.13e-219 - - - S - - - Protein of unknown function (DUF3801)
HGHNDNDD_01339 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
HGHNDNDD_01340 2.52e-56 - - - S - - - Bacterial mobilisation protein (MobC)
HGHNDNDD_01341 7.13e-56 - - - K - - - Protein of unknown function (DUF2442)
HGHNDNDD_01342 1.84e-59 - - - S - - - Domain of unknown function (DUF4160)
HGHNDNDD_01344 1.94e-41 - - - - - - - -
HGHNDNDD_01345 5.79e-62 - - - - - - - -
HGHNDNDD_01346 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
HGHNDNDD_01347 1.32e-92 - - - - - - - -
HGHNDNDD_01348 3.93e-73 - - - - - - - -
HGHNDNDD_01349 1.14e-75 - - - - - - - -
HGHNDNDD_01350 9.24e-35 - - - - - - - -
HGHNDNDD_01351 2.81e-182 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HGHNDNDD_01352 0.0 intA - - L - - - Phage integrase family
HGHNDNDD_01353 1.08e-97 - - - - - - - -
HGHNDNDD_01355 3.72e-177 - - - S - - - HipA-like C-terminal domain
HGHNDNDD_01356 6.29e-29 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGHNDNDD_01357 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
HGHNDNDD_01358 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
HGHNDNDD_01359 5.09e-223 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01360 2.49e-155 - - - G ko:K02025,ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01361 2.82e-160 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01362 1.14e-278 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
HGHNDNDD_01363 6.86e-174 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_01364 5.75e-306 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HGHNDNDD_01365 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
HGHNDNDD_01366 1.59e-42 - - - - - - - -
HGHNDNDD_01367 6.15e-170 - - - C - - - Putative TM nitroreductase
HGHNDNDD_01368 3.5e-220 - - - EG - - - EamA-like transporter family
HGHNDNDD_01369 2.86e-93 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
HGHNDNDD_01370 2.01e-294 - - - L - - - ribosomal rna small subunit methyltransferase
HGHNDNDD_01371 1.22e-214 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HGHNDNDD_01372 4.06e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HGHNDNDD_01373 1.52e-205 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HGHNDNDD_01374 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HGHNDNDD_01375 5.86e-144 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
HGHNDNDD_01376 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
HGHNDNDD_01377 2.4e-219 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HGHNDNDD_01378 6.13e-112 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
HGHNDNDD_01379 1.63e-200 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
HGHNDNDD_01380 1.16e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
HGHNDNDD_01381 1.32e-249 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGHNDNDD_01383 5.21e-155 - - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_01384 9.19e-303 - - - T - - - Histidine kinase
HGHNDNDD_01386 3.84e-91 - - - - - - - -
HGHNDNDD_01387 1.99e-182 - - - - ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HGHNDNDD_01388 5.11e-181 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGHNDNDD_01389 3.65e-251 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HGHNDNDD_01390 2.57e-59 - - - L - - - PFAM Relaxase mobilization nuclease family protein
HGHNDNDD_01391 7.14e-183 - - - S - - - Fic/DOC family
HGHNDNDD_01393 2.93e-05 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
HGHNDNDD_01394 1.77e-66 - - - L - - - Phage integrase family
HGHNDNDD_01396 2.35e-47 - - - M - - - Peptidase family M23
HGHNDNDD_01397 0.0 - - - G - - - ABC transporter substrate-binding protein
HGHNDNDD_01398 2e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
HGHNDNDD_01399 5.94e-262 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
HGHNDNDD_01400 5.83e-120 - - - - - - - -
HGHNDNDD_01401 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
HGHNDNDD_01402 1.96e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGHNDNDD_01403 2.69e-192 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HGHNDNDD_01404 7.92e-187 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGHNDNDD_01405 3.81e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HGHNDNDD_01406 2.88e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGHNDNDD_01407 8.23e-223 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
HGHNDNDD_01408 5.52e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HGHNDNDD_01409 6.98e-99 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HGHNDNDD_01410 4.13e-180 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGHNDNDD_01411 2.28e-93 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HGHNDNDD_01412 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGHNDNDD_01413 1.15e-119 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
HGHNDNDD_01414 1.37e-226 - - - - - - - -
HGHNDNDD_01415 2.79e-97 - - - - - - - -
HGHNDNDD_01416 1.3e-82 - - - K - - - Protein of unknown function, DUF488
HGHNDNDD_01417 5.32e-11 - - - - - - - -
HGHNDNDD_01418 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
HGHNDNDD_01420 1.04e-64 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
HGHNDNDD_01421 1.49e-53 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HGHNDNDD_01423 4.5e-129 - - - S - - - Acetyltransferase (GNAT) domain
HGHNDNDD_01424 1.81e-42 cefD 5.1.1.17 - E ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Aminotransferase, class V
HGHNDNDD_01425 3.02e-19 cefD 5.1.1.17 - E ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Aminotransferase, class V
HGHNDNDD_01426 1.71e-240 - - - V - - - VanZ like family
HGHNDNDD_01427 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
HGHNDNDD_01428 4.89e-202 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGHNDNDD_01429 1.84e-170 - - - S - - - SOS response associated peptidase (SRAP)
HGHNDNDD_01430 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGHNDNDD_01431 7.23e-207 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGHNDNDD_01432 5.51e-240 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGHNDNDD_01433 5.04e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
HGHNDNDD_01434 5.07e-56 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
HGHNDNDD_01435 3.05e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
HGHNDNDD_01436 2.32e-138 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGHNDNDD_01437 3.77e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
HGHNDNDD_01438 6.08e-61 sbp - - S - - - Protein of unknown function (DUF1290)
HGHNDNDD_01439 1.13e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
HGHNDNDD_01440 2.02e-97 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
HGHNDNDD_01441 2.6e-142 merR2 - - K - - - helix_turn_helix, mercury resistance
HGHNDNDD_01442 2.25e-86 - - - - - - - -
HGHNDNDD_01443 9.48e-49 - - - - - - - -
HGHNDNDD_01444 2.15e-178 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
HGHNDNDD_01445 3.18e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HGHNDNDD_01446 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
HGHNDNDD_01447 9.96e-69 - - - - - - - -
HGHNDNDD_01448 0.0 - - - K - - - WYL domain
HGHNDNDD_01449 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HGHNDNDD_01450 1.12e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HGHNDNDD_01452 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HGHNDNDD_01453 9.06e-184 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HGHNDNDD_01454 9.04e-180 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HGHNDNDD_01455 3.55e-43 - - - - - - - -
HGHNDNDD_01456 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HGHNDNDD_01457 3.8e-294 - - - - - - - -
HGHNDNDD_01458 5.31e-211 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGHNDNDD_01459 4.18e-282 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HGHNDNDD_01460 5.54e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGHNDNDD_01461 6.21e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
HGHNDNDD_01462 1.82e-255 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGHNDNDD_01463 4.14e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGHNDNDD_01464 4.21e-131 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HGHNDNDD_01465 1.19e-156 yebC - - K - - - transcriptional regulatory protein
HGHNDNDD_01466 3.78e-143 - 2.7.7.53 - FG ko:K19710 ko00230,map00230 ko00000,ko00001,ko01000 HIT domain
HGHNDNDD_01467 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGHNDNDD_01473 5.33e-170 - - - S - - - PAC2 family
HGHNDNDD_01474 8.71e-201 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGHNDNDD_01475 7.54e-200 - - - G - - - Fructosamine kinase
HGHNDNDD_01476 6.57e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGHNDNDD_01477 8.14e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGHNDNDD_01478 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
HGHNDNDD_01479 1.1e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGHNDNDD_01480 5.79e-305 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HGHNDNDD_01481 1.48e-242 - - - - - - - -
HGHNDNDD_01482 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
HGHNDNDD_01483 1.64e-204 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HGHNDNDD_01484 4.61e-223 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HGHNDNDD_01485 2.51e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HGHNDNDD_01486 1.7e-188 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHNDNDD_01487 1.02e-278 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
HGHNDNDD_01488 2.86e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HGHNDNDD_01489 6.34e-228 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HGHNDNDD_01490 4.9e-239 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
HGHNDNDD_01491 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGHNDNDD_01492 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGHNDNDD_01493 3.94e-294 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
HGHNDNDD_01494 3.56e-120 - - - S ko:K16926 - ko00000,ko00002,ko02000 Hypothetical bacterial integral membrane protein (Trep_Strep)
HGHNDNDD_01495 7.88e-120 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGHNDNDD_01496 5.24e-168 - - - S - - - Enoyl-(Acyl carrier protein) reductase
HGHNDNDD_01497 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
HGHNDNDD_01498 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGHNDNDD_01499 7.85e-157 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGHNDNDD_01500 1.55e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HGHNDNDD_01501 8.27e-273 - - - S - - - Psort location Cytoplasmic, score 8.87
HGHNDNDD_01502 1.08e-39 - - - - - - - -
HGHNDNDD_01503 4.64e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGHNDNDD_01504 6.62e-231 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGHNDNDD_01505 2.25e-202 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HGHNDNDD_01506 6.06e-224 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
HGHNDNDD_01507 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGHNDNDD_01508 2.61e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HGHNDNDD_01509 4.95e-226 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HGHNDNDD_01510 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HGHNDNDD_01511 8.46e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHNDNDD_01512 9.57e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HGHNDNDD_01513 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGHNDNDD_01515 1.18e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
HGHNDNDD_01516 1.56e-257 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HGHNDNDD_01517 7.17e-171 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HGHNDNDD_01519 4.16e-181 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGHNDNDD_01520 7.79e-185 - - - S - - - phosphoesterase or phosphohydrolase
HGHNDNDD_01521 2.27e-106 lppD - - S - - - Appr-1'-p processing enzyme
HGHNDNDD_01522 2.49e-229 - - - I - - - alpha/beta hydrolase fold
HGHNDNDD_01524 4.65e-107 - - - - - - - -
HGHNDNDD_01525 1.72e-135 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
HGHNDNDD_01526 7.27e-207 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HGHNDNDD_01527 2.95e-202 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01528 1.87e-309 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
HGHNDNDD_01529 4.31e-104 - - - - - - - -
HGHNDNDD_01530 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
HGHNDNDD_01531 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HGHNDNDD_01532 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HGHNDNDD_01533 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
HGHNDNDD_01534 3.21e-243 - - - K - - - helix_turn _helix lactose operon repressor
HGHNDNDD_01536 0.0 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HGHNDNDD_01537 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGHNDNDD_01538 5.55e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HGHNDNDD_01539 3.96e-178 - - - S - - - UPF0126 domain
HGHNDNDD_01540 6.23e-189 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 Psort location Cytoplasmic, score 8.87
HGHNDNDD_01541 2.72e-288 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
HGHNDNDD_01542 1.75e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGHNDNDD_01543 1.77e-299 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HGHNDNDD_01544 5.19e-309 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HGHNDNDD_01545 2.06e-57 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
HGHNDNDD_01546 2.32e-261 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
HGHNDNDD_01547 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HGHNDNDD_01548 3.86e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGHNDNDD_01549 0.0 corC - - S - - - CBS domain
HGHNDNDD_01550 1.33e-133 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGHNDNDD_01551 9.79e-278 phoH - - T ko:K06217 - ko00000 PhoH-like protein
HGHNDNDD_01552 2.76e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HGHNDNDD_01553 3.11e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGHNDNDD_01555 7.89e-212 spoU2 - - J - - - SpoU rRNA Methylase family
HGHNDNDD_01556 1.6e-309 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGHNDNDD_01557 8.91e-142 - - - S - - - Iron-sulfur cluster assembly protein
HGHNDNDD_01558 8.33e-133 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HGHNDNDD_01559 1.25e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGHNDNDD_01560 2.81e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HGHNDNDD_01561 2.51e-300 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
HGHNDNDD_01562 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
HGHNDNDD_01563 0.0 - - - S - - - L,D-transpeptidase catalytic domain
HGHNDNDD_01564 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGHNDNDD_01565 1.07e-121 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_01566 8.53e-104 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HGHNDNDD_01567 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGHNDNDD_01568 8.69e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGHNDNDD_01569 2.48e-91 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
HGHNDNDD_01570 4.21e-252 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGHNDNDD_01571 2.12e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGHNDNDD_01572 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGHNDNDD_01573 6.59e-48 - - - - - - - -
HGHNDNDD_01574 1.28e-76 - - - S - - - Bacterial protein of unknown function (DUF948)
HGHNDNDD_01575 4.04e-165 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
HGHNDNDD_01576 8.55e-64 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HGHNDNDD_01577 6.1e-85 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
HGHNDNDD_01578 1.07e-136 - - - E - - - Transglutaminase-like superfamily
HGHNDNDD_01579 2.59e-68 - - - S - - - SdpI/YhfL protein family
HGHNDNDD_01580 1.43e-115 - 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 cytidine deaminase activity
HGHNDNDD_01581 9.91e-199 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
HGHNDNDD_01582 5.26e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGHNDNDD_01583 2.94e-208 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGHNDNDD_01584 6.33e-275 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HGHNDNDD_01585 2.56e-81 - - - S - - - Domain of unknown function (DUF4418)
HGHNDNDD_01586 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGHNDNDD_01587 1.48e-135 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGHNDNDD_01588 2.21e-309 pbuX - - F ko:K03458 - ko00000 Permease family
HGHNDNDD_01589 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGHNDNDD_01590 1.11e-54 - - - S - - - Protein of unknown function (DUF2975)
HGHNDNDD_01591 2.08e-202 - - - I - - - Serine aminopeptidase, S33
HGHNDNDD_01592 2.18e-218 - - - M - - - pfam nlp p60
HGHNDNDD_01593 9.18e-137 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
HGHNDNDD_01594 9.04e-137 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
HGHNDNDD_01595 6.11e-262 - - - - - - - -
HGHNDNDD_01596 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HGHNDNDD_01597 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGHNDNDD_01598 2.28e-289 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGHNDNDD_01599 1.88e-225 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01600 2.98e-146 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HGHNDNDD_01601 6.28e-306 - - - T - - - Histidine kinase
HGHNDNDD_01602 8e-145 - - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_01603 2.73e-147 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
HGHNDNDD_01604 1.25e-241 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
HGHNDNDD_01605 3e-309 nplT 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HGHNDNDD_01606 0.0 - - - JKL - - - helicase superfamily c-terminal domain
HGHNDNDD_01607 8.07e-297 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
HGHNDNDD_01608 1.72e-207 - - - G - - - Phosphoglycerate mutase family
HGHNDNDD_01609 1.48e-135 - - - E - - - haloacid dehalogenase-like hydrolase
HGHNDNDD_01610 5.8e-306 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HGHNDNDD_01612 3.12e-79 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGHNDNDD_01613 5.16e-164 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HGHNDNDD_01614 1.18e-75 - - - L ko:K07483 - ko00000 Integrase core domain
HGHNDNDD_01615 1.6e-54 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_01616 1.78e-68 - - - L - - - Helix-turn-helix domain
HGHNDNDD_01617 2.15e-155 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HGHNDNDD_01618 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
HGHNDNDD_01619 0.0 - - - P - - - Domain of unknown function (DUF4976)
HGHNDNDD_01620 0.0 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
HGHNDNDD_01621 1.11e-200 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
HGHNDNDD_01622 5.66e-277 - - - GK - - - ROK family
HGHNDNDD_01623 3.35e-220 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HGHNDNDD_01624 1.01e-187 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHNDNDD_01625 1.53e-307 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
HGHNDNDD_01626 7.34e-29 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGHNDNDD_01627 9.48e-82 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGHNDNDD_01629 2.13e-94 - - - I - - - Sterol carrier protein
HGHNDNDD_01630 1.64e-163 - - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_01631 4.35e-102 - - - EGP - - - Major Facilitator Superfamily
HGHNDNDD_01632 2.53e-168 - - - T - - - Histidine kinase
HGHNDNDD_01633 4.19e-58 - - - S - - - Protein of unknown function (DUF3073)
HGHNDNDD_01634 5.93e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HGHNDNDD_01635 0.0 - - - S - - - Amidohydrolase family
HGHNDNDD_01636 1.22e-204 - - - S - - - Protein conserved in bacteria
HGHNDNDD_01637 0.0 - - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGHNDNDD_01638 0.0 - - - S - - - Threonine/Serine exporter, ThrE
HGHNDNDD_01639 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HGHNDNDD_01640 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HGHNDNDD_01641 2.3e-121 - - - S ko:K07133 - ko00000 AAA domain
HGHNDNDD_01642 0.0 - 3.1.4.52 - T ko:K14051 ko02024,ko02026,map02024,map02026 ko00000,ko00001,ko01000 Putative diguanylate phosphodiesterase
HGHNDNDD_01643 1.72e-142 - - - S - - - Domain of unknown function (DUF4956)
HGHNDNDD_01644 1.93e-203 - - - P - - - VTC domain
HGHNDNDD_01645 0.0 - - - M ko:K06330 - ko00000 CotH kinase protein
HGHNDNDD_01646 0.0 - - - S ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
HGHNDNDD_01647 0.0 - - GT4 M ko:K21011 ko02025,map02025 ko00000,ko00001,ko01003 Domain of unknown function (DUF3492)
HGHNDNDD_01648 4.56e-270 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
HGHNDNDD_01649 4.19e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
HGHNDNDD_01650 9.11e-208 - - - - - - - -
HGHNDNDD_01651 0.0 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 ADP-glyceromanno-heptose 6-epimerase activity
HGHNDNDD_01652 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HGHNDNDD_01653 6.83e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
HGHNDNDD_01654 8.63e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HGHNDNDD_01655 6.23e-266 - - - S - - - AAA ATPase domain
HGHNDNDD_01656 6.91e-298 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
HGHNDNDD_01657 2.58e-108 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HGHNDNDD_01658 0.0 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01659 5.95e-240 - - - K ko:K05499 - ko00000,ko03000 Periplasmic binding protein-like domain
HGHNDNDD_01660 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01661 5.07e-293 - - - M - - - Protein of unknown function (DUF2961)
HGHNDNDD_01663 4.38e-147 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01664 1.28e-95 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01665 1.1e-91 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_01666 2.79e-38 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_01668 1.1e-198 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01669 3.16e-195 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HGHNDNDD_01670 7.96e-93 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HGHNDNDD_01671 8.25e-63 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HGHNDNDD_01672 2.65e-185 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
HGHNDNDD_01673 3.1e-270 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_01674 2.43e-240 - - - K - - - Psort location Cytoplasmic, score
HGHNDNDD_01675 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HGHNDNDD_01676 1.29e-313 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01677 0.0 - 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
HGHNDNDD_01678 3.26e-253 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
HGHNDNDD_01679 3.39e-148 - - - S - - - Protein of unknown function, DUF624
HGHNDNDD_01680 9.48e-111 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01681 6.35e-147 - - - L - - - Transposase and inactivated derivatives IS30 family
HGHNDNDD_01682 3.14e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HGHNDNDD_01683 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_01684 2.17e-55 gntK 2.7.1.12, 2.7.1.71 - F ko:K00851,ko:K00891 ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate kinase
HGHNDNDD_01685 1.75e-185 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
HGHNDNDD_01686 8.71e-257 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HGHNDNDD_01687 1.82e-23 - - - S - - - Haloacid dehalogenase-like hydrolase
HGHNDNDD_01688 1.12e-24 - - - K - - - Transcriptional regulator, rpir family
HGHNDNDD_01689 2.02e-145 - - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
HGHNDNDD_01690 1.7e-104 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HGHNDNDD_01691 7.25e-101 - - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01692 2.35e-104 ptxC - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01693 1.22e-73 - - - F - - - Calcineurin-like phosphoesterase
HGHNDNDD_01694 9.07e-31 - - - L ko:K07485 - ko00000 Transposase
HGHNDNDD_01697 2.56e-252 - - - S - - - Psort location CytoplasmicMembrane, score
HGHNDNDD_01698 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGHNDNDD_01699 1.19e-259 - - - V - - - VanZ like family
HGHNDNDD_01700 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
HGHNDNDD_01701 7.85e-14 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HGHNDNDD_01702 4.7e-238 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HGHNDNDD_01703 1.22e-88 - - - S - - - Transmembrane domain of unknown function (DUF3566)
HGHNDNDD_01704 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHNDNDD_01705 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHNDNDD_01706 3.41e-107 - - - S - - - Protein of unknown function (DUF721)
HGHNDNDD_01707 2.64e-255 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGHNDNDD_01708 5.94e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGHNDNDD_01710 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGHNDNDD_01711 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HGHNDNDD_01712 5.08e-74 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGHNDNDD_01713 1.7e-235 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
HGHNDNDD_01714 1.97e-119 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
HGHNDNDD_01715 3.56e-159 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HGHNDNDD_01716 6.3e-224 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HGHNDNDD_01717 1.3e-282 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HGHNDNDD_01718 4.24e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGHNDNDD_01719 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
HGHNDNDD_01720 0.0 - - - - - - - -
HGHNDNDD_01721 5.27e-211 mutT4 - - L - - - Belongs to the Nudix hydrolase family
HGHNDNDD_01722 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
HGHNDNDD_01723 5.91e-143 - - - S - - - LytR cell envelope-related transcriptional attenuator
HGHNDNDD_01724 1.05e-223 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGHNDNDD_01725 3.21e-215 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGHNDNDD_01726 1.54e-282 rpfB - - S ko:K21688 - ko00000 G5
HGHNDNDD_01728 5.12e-181 - - - O - - - Thioredoxin
HGHNDNDD_01729 0.0 - - - KLT - - - Protein tyrosine kinase
HGHNDNDD_01730 9.19e-153 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
HGHNDNDD_01731 4.57e-152 - - - T - - - LytTr DNA-binding domain
HGHNDNDD_01732 2.82e-167 - - - T - - - GHKL domain
HGHNDNDD_01733 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
HGHNDNDD_01734 4.49e-78 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HGHNDNDD_01735 5.67e-16 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HGHNDNDD_01736 2.06e-161 - - - S - - - Protein of unknown function (DUF3990)
HGHNDNDD_01737 3.18e-155 - - - K - - - Helix-turn-helix XRE-family like proteins
HGHNDNDD_01738 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HGHNDNDD_01739 6.17e-158 - - - S - - - Psort location CytoplasmicMembrane, score
HGHNDNDD_01741 1.62e-57 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HGHNDNDD_01742 8.2e-113 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HGHNDNDD_01743 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHNDNDD_01745 2.96e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHNDNDD_01746 9.3e-272 - - - M - - - Glycosyltransferase like family 2
HGHNDNDD_01747 5.55e-94 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHNDNDD_01748 3.61e-61 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HGHNDNDD_01749 1.55e-307 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HGHNDNDD_01750 1.02e-175 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
HGHNDNDD_01751 7.62e-270 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGHNDNDD_01752 2.62e-27 - - - L - - - Winged helix-turn helix
HGHNDNDD_01754 3.33e-232 - - - - - - - -
HGHNDNDD_01755 6.14e-191 - - - U ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HGHNDNDD_01756 3.89e-223 rbsA 3.6.3.17 - G ko:K10441,ko:K10542,ko:K17215 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01757 1.62e-185 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
HGHNDNDD_01758 1.19e-168 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_01759 2e-18 tnp3521a2 - - L - - - Integrase core domain
HGHNDNDD_01760 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
HGHNDNDD_01761 7.17e-313 - - - M - - - LPXTG-motif cell wall anchor domain protein
HGHNDNDD_01762 2.7e-232 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGHNDNDD_01763 5.25e-198 - - - - - - - -
HGHNDNDD_01764 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
HGHNDNDD_01765 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HGHNDNDD_01766 1.54e-215 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
HGHNDNDD_01767 2.26e-222 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHNDNDD_01768 2.78e-273 - - - EGP - - - Transmembrane secretion effector
HGHNDNDD_01769 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HGHNDNDD_01770 1.58e-112 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHNDNDD_01771 1.55e-20 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGHNDNDD_01772 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HGHNDNDD_01773 1.23e-122 - - - - - - - -
HGHNDNDD_01774 4.97e-143 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
HGHNDNDD_01775 3.67e-195 - - - - - - - -
HGHNDNDD_01776 4.34e-189 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
HGHNDNDD_01777 1.77e-159 - - - S ko:K07090 - ko00000 membrane transporter protein
HGHNDNDD_01778 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
HGHNDNDD_01779 1.6e-107 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGHNDNDD_01780 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
HGHNDNDD_01781 9.36e-296 - - - GK - - - ROK family
HGHNDNDD_01782 1.62e-312 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGHNDNDD_01783 1.9e-208 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01784 7.15e-197 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01785 3.73e-239 - - - K - - - Periplasmic binding protein domain
HGHNDNDD_01786 9.84e-178 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
HGHNDNDD_01787 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGHNDNDD_01788 2.13e-192 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGHNDNDD_01789 7.3e-221 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01790 4.57e-217 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
HGHNDNDD_01791 5.5e-196 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
HGHNDNDD_01792 9.36e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGHNDNDD_01793 2.45e-203 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
HGHNDNDD_01794 1.9e-206 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
HGHNDNDD_01795 2.17e-267 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
HGHNDNDD_01796 2.52e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGHNDNDD_01797 0.0 - - - L - - - Psort location Cytoplasmic, score
HGHNDNDD_01798 2.62e-159 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGHNDNDD_01799 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGHNDNDD_01800 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
HGHNDNDD_01801 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHNDNDD_01802 2.06e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGHNDNDD_01803 1.13e-170 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGHNDNDD_01804 9.12e-299 - - - G - - - Major Facilitator Superfamily
HGHNDNDD_01805 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
HGHNDNDD_01806 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
HGHNDNDD_01807 1.25e-283 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HGHNDNDD_01808 0.0 - - - S - - - Fibronectin type 3 domain
HGHNDNDD_01809 1.87e-307 - - - S - - - Protein of unknown function DUF58
HGHNDNDD_01810 0.0 - - - E - - - Transglutaminase-like superfamily
HGHNDNDD_01811 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHNDNDD_01812 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHNDNDD_01813 1.49e-163 - - - - - - - -
HGHNDNDD_01814 1.77e-238 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
HGHNDNDD_01815 3.37e-148 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGHNDNDD_01816 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
HGHNDNDD_01817 7.93e-59 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HGHNDNDD_01818 6.15e-299 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
HGHNDNDD_01819 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
HGHNDNDD_01820 5.12e-158 - - - K - - - DeoR C terminal sensor domain
HGHNDNDD_01821 3.6e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HGHNDNDD_01822 2.35e-303 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HGHNDNDD_01823 0.0 pon1 - - M - - - Transglycosylase
HGHNDNDD_01824 1.56e-171 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HGHNDNDD_01825 6.49e-277 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
HGHNDNDD_01826 2.55e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HGHNDNDD_01827 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
HGHNDNDD_01828 4.05e-284 - - - S - - - Uncharacterized conserved protein (DUF2183)
HGHNDNDD_01829 1.26e-91 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HGHNDNDD_01830 8.43e-282 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HGHNDNDD_01831 9.51e-203 - - - I - - - Alpha/beta hydrolase family
HGHNDNDD_01832 7.47e-156 - - - F - - - Domain of unknown function (DUF4916)
HGHNDNDD_01833 5.55e-79 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
HGHNDNDD_01834 1.79e-221 - - - S ko:K21688 - ko00000 G5
HGHNDNDD_01835 5.44e-261 - - - - - - - -
HGHNDNDD_01836 2.7e-313 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
HGHNDNDD_01837 2.88e-91 - - - - - - - -
HGHNDNDD_01838 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HGHNDNDD_01839 7.2e-15 - - - L - - - Helix-turn-helix domain
HGHNDNDD_01840 1.72e-28 - - - S - - - enterobacterial common antigen metabolic process
HGHNDNDD_01841 9.34e-234 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
HGHNDNDD_01842 1.24e-116 - - - S - - - RloB-like protein
HGHNDNDD_01844 3.34e-35 - - - T - - - RNA ligase
HGHNDNDD_01845 1.37e-22 - - - S - - - Domain of unknown function DUF1829
HGHNDNDD_01846 1.62e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGHNDNDD_01847 6.32e-164 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGHNDNDD_01848 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
HGHNDNDD_01849 0.0 - - - T - - - Histidine kinase
HGHNDNDD_01850 2.76e-165 - - - K - - - helix_turn_helix, Lux Regulon
HGHNDNDD_01851 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HGHNDNDD_01852 1.34e-158 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGHNDNDD_01853 3.67e-311 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
HGHNDNDD_01854 1.53e-208 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HGHNDNDD_01855 8.53e-120 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
HGHNDNDD_01856 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
HGHNDNDD_01857 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
HGHNDNDD_01858 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
HGHNDNDD_01859 3.14e-228 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HGHNDNDD_01860 4.44e-143 safC - - S - - - O-methyltransferase
HGHNDNDD_01861 1.01e-204 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HGHNDNDD_01862 1.27e-308 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HGHNDNDD_01865 1.39e-310 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGHNDNDD_01866 2.2e-159 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGHNDNDD_01867 4.2e-151 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGHNDNDD_01868 2.42e-79 - - - - - - - -
HGHNDNDD_01869 8.99e-301 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HGHNDNDD_01870 2.73e-301 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGHNDNDD_01871 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
HGHNDNDD_01872 1.92e-153 - - - S - - - Protein of unknown function (DUF3000)
HGHNDNDD_01873 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHNDNDD_01874 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HGHNDNDD_01875 6.14e-52 - - - - - - - -
HGHNDNDD_01876 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGHNDNDD_01877 2.31e-284 - - - S - - - Peptidase dimerisation domain
HGHNDNDD_01878 3.9e-146 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGHNDNDD_01879 2.32e-279 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHNDNDD_01880 1.81e-225 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
HGHNDNDD_01881 3.85e-199 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HGHNDNDD_01882 7.51e-178 - - - S - - - Protein conserved in bacteria
HGHNDNDD_01885 6.88e-44 - - - D - - - FtsK/SpoIIIE family
HGHNDNDD_01888 1.66e-50 intA - - L - - - Phage integrase family
HGHNDNDD_01891 7.2e-174 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HGHNDNDD_01892 5.45e-86 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGHNDNDD_01893 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGHNDNDD_01894 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HGHNDNDD_01895 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HGHNDNDD_01896 6.7e-21 - - - - - - - -
HGHNDNDD_01897 2.96e-08 - - - - - - - -
HGHNDNDD_01898 1.46e-37 - - - - - - - -
HGHNDNDD_01899 7.88e-66 - - - S - - - Putative DNA-binding domain
HGHNDNDD_01900 1.11e-138 - 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HGHNDNDD_01902 3.91e-82 - - - S - - - Protein of unknown function (DUF2992)
HGHNDNDD_01903 4.62e-225 - - - V - - - Abi-like protein
HGHNDNDD_01904 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
HGHNDNDD_01905 5.58e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHNDNDD_01907 1.62e-295 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHNDNDD_01908 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGHNDNDD_01909 3.26e-274 - - - - - - - -
HGHNDNDD_01910 1.5e-155 - - - - - - - -
HGHNDNDD_01912 4.71e-25 - 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HGHNDNDD_01913 4.19e-160 - - - S - - - GyrI-like small molecule binding domain
HGHNDNDD_01914 3.52e-116 - - - K - - - Putative zinc ribbon domain
HGHNDNDD_01915 9.31e-36 zntR - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HGHNDNDD_01916 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
HGHNDNDD_01917 4e-162 - - - L - - - NUDIX domain
HGHNDNDD_01918 4.64e-227 - - - L - - - NIF3 (NGG1p interacting factor 3)
HGHNDNDD_01919 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGHNDNDD_01920 1.77e-168 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
HGHNDNDD_01922 1.12e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HGHNDNDD_01923 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)