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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PLHIGLEE_00001	1.3e-238	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
PLHIGLEE_00002	4.14e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
PLHIGLEE_00003	5.11e-288	-	-	-	I	-	-	-	Serine aminopeptidase, S33
PLHIGLEE_00004	1.19e-05	-	-	-	K	-	-	-	Periplasmic binding protein LacI transcriptional regulator
PLHIGLEE_00005	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
PLHIGLEE_00006	4.93e-141	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PLHIGLEE_00007	0.0	-	2.1.1.72	-	L	ko:K07317	-	ko00000,ko01000,ko02048	Eco57I restriction-modification methylase
PLHIGLEE_00008	4.27e-223	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	BsuBI/PstI restriction endonuclease C-terminus
PLHIGLEE_00009	1.17e-287	-	-	-	-	-	-	-	-
PLHIGLEE_00011	8.1e-236	-	-	-	L	-	-	-	Phage integrase family
PLHIGLEE_00012	9.53e-07	-	-	-	M	-	-	-	PA domain
PLHIGLEE_00013	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PLHIGLEE_00014	8e-163	gntR	-	-	K	-	-	-	FCD
PLHIGLEE_00015	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PLHIGLEE_00016	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
PLHIGLEE_00019	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
PLHIGLEE_00020	1.47e-77	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_00021	1.29e-139	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_00022	6.23e-102	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PLHIGLEE_00023	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PLHIGLEE_00024	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PLHIGLEE_00025	5.11e-176	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
PLHIGLEE_00026	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PLHIGLEE_00027	2.83e-240	-	-	-	EG	-	-	-	EamA-like transporter family
PLHIGLEE_00028	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PLHIGLEE_00029	2.3e-122	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_00030	4.99e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
PLHIGLEE_00031	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
PLHIGLEE_00032	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
PLHIGLEE_00033	9.66e-309	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PLHIGLEE_00034	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PLHIGLEE_00035	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PLHIGLEE_00036	2.5e-197	-	-	-	S	-	-	-	Amidohydrolase family
PLHIGLEE_00037	3.86e-21	-	-	-	S	-	-	-	Amidohydrolase family
PLHIGLEE_00038	4.09e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
PLHIGLEE_00039	1.2e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PLHIGLEE_00040	5.42e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
PLHIGLEE_00041	2.24e-112	-	-	-	K	-	-	-	LytTr DNA-binding domain
PLHIGLEE_00042	1.21e-17	-	-	-	T	-	-	-	protein histidine kinase activity
PLHIGLEE_00043	8.5e-99	-	-	-	T	-	-	-	protein histidine kinase activity
PLHIGLEE_00044	1.14e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PLHIGLEE_00045	8.14e-39	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PLHIGLEE_00046	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PLHIGLEE_00047	3.57e-235	-	-	GT2	M	ko:K13670	-	ko00000,ko01000	Glycosyltransferase like family 2
PLHIGLEE_00048	6.25e-176	tnp3521a2	-	-	L	-	-	-	Integrase core domain
PLHIGLEE_00050	1.56e-159	istB	-	-	L	-	-	-	IstB-like ATP binding protein
PLHIGLEE_00051	1.38e-158	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00052	2.09e-159	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00053	3.24e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00054	2.28e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00055	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
PLHIGLEE_00056	0.0	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
PLHIGLEE_00057	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
PLHIGLEE_00058	6.01e-246	-	-	-	I	-	-	-	Acyltransferase family
PLHIGLEE_00059	5.05e-93	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
PLHIGLEE_00060	5.35e-107	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	transposase activity
PLHIGLEE_00061	4.94e-105	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00062	1.58e-35	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00063	3.08e-207	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00064	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00065	3.27e-184	istB	-	-	L	-	-	-	IstB-like ATP binding protein
PLHIGLEE_00066	2.3e-169	istB	-	-	L	-	-	-	IstB-like ATP binding protein
PLHIGLEE_00067	1.05e-208	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00068	2.77e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PLHIGLEE_00069	1.79e-138	-	-	-	-	-	-	-	-
PLHIGLEE_00070	1.31e-57	tnp3521a2	-	-	L	-	-	-	Integrase core domain
PLHIGLEE_00071	9.11e-69	tnp3521a2	-	-	L	-	-	-	Integrase core domain
PLHIGLEE_00072	5.3e-73	-	-	-	L	ko:K07483	-	ko00000	transposase activity
PLHIGLEE_00073	1.1e-31	-	-	-	-	-	-	-	-
PLHIGLEE_00074	2.49e-14	-	-	-	L	ko:K07485	-	ko00000	Transposase
PLHIGLEE_00075	1.9e-51	-	-	-	L	-	-	-	Transposase
PLHIGLEE_00076	3.78e-219	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PLHIGLEE_00077	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PLHIGLEE_00078	3.56e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PLHIGLEE_00079	2.32e-197	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
PLHIGLEE_00080	2.01e-305	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_00081	6.79e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
PLHIGLEE_00082	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
PLHIGLEE_00083	1.53e-24	yccF	-	-	S	-	-	-	Inner membrane component domain
PLHIGLEE_00084	1.9e-17	-	-	-	-	-	-	-	-
PLHIGLEE_00085	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
PLHIGLEE_00086	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
PLHIGLEE_00087	2.11e-46	istB	-	-	L	-	-	-	IstB-like ATP binding protein
PLHIGLEE_00088	2.19e-60	-	-	-	L	ko:K07485	-	ko00000	Transposase
PLHIGLEE_00089	2.07e-22	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00090	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
PLHIGLEE_00091	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PLHIGLEE_00092	7.68e-47	-	-	-	-	-	-	-	-
PLHIGLEE_00093	1.19e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
PLHIGLEE_00094	5.53e-154	-	-	-	L	-	-	-	HTH-like domain
PLHIGLEE_00095	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
PLHIGLEE_00096	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
PLHIGLEE_00097	1.18e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
PLHIGLEE_00098	5.65e-296	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PLHIGLEE_00099	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
PLHIGLEE_00100	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
PLHIGLEE_00101	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
PLHIGLEE_00102	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
PLHIGLEE_00103	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PLHIGLEE_00104	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
PLHIGLEE_00105	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
PLHIGLEE_00106	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
PLHIGLEE_00107	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
PLHIGLEE_00108	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
PLHIGLEE_00109	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
PLHIGLEE_00110	2.07e-264	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
PLHIGLEE_00111	2.55e-213	-	-	-	EG	-	-	-	EamA-like transporter family
PLHIGLEE_00112	1.35e-146	-	-	-	-	-	-	-	-
PLHIGLEE_00114	1.17e-250	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PLHIGLEE_00116	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
PLHIGLEE_00117	9.14e-117	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PLHIGLEE_00118	9.18e-60	-	-	-	D	-	-	-	DivIVA domain protein
PLHIGLEE_00119	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
PLHIGLEE_00120	1.58e-199	-	-	-	I	-	-	-	Serine aminopeptidase, S33
PLHIGLEE_00121	4.51e-110	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
PLHIGLEE_00123	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PLHIGLEE_00124	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
PLHIGLEE_00125	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
PLHIGLEE_00126	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
PLHIGLEE_00127	2.55e-218	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PLHIGLEE_00132	6.8e-169	-	-	-	M	-	-	-	NLP P60 protein
PLHIGLEE_00133	3.67e-88	-	-	-	S	-	-	-	SPP1 phage holin
PLHIGLEE_00135	4.92e-90	-	-	-	-	-	-	-	-
PLHIGLEE_00136	2.04e-32	-	-	-	L	-	-	-	DNA integration
PLHIGLEE_00137	1.69e-109	-	-	-	-	-	-	-	-
PLHIGLEE_00139	6.16e-295	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_00140	5.08e-135	-	-	-	-	-	-	-	-
PLHIGLEE_00141	5.54e-144	-	-	-	NT	-	-	-	phage tail tape measure protein
PLHIGLEE_00144	2.1e-84	-	-	-	N	-	-	-	domain, Protein
PLHIGLEE_00145	1.83e-48	-	-	-	-	-	-	-	-
PLHIGLEE_00147	1.23e-41	-	-	-	-	-	-	-	-
PLHIGLEE_00148	1.89e-19	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
PLHIGLEE_00149	2.34e-189	-	-	-	S	-	-	-	Phage capsid family
PLHIGLEE_00150	2.87e-38	-	-	-	-	-	-	-	-
PLHIGLEE_00151	4.14e-56	-	-	-	-	-	-	-	-
PLHIGLEE_00152	7.48e-104	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PLHIGLEE_00153	1.09e-184	-	-	-	S	-	-	-	Terminase
PLHIGLEE_00157	4.48e-82	-	-	-	EH	-	-	-	sulfate reduction
PLHIGLEE_00159	4.25e-24	-	-	-	V	-	-	-	HNH nucleases
PLHIGLEE_00161	6.34e-90	-	-	-	-	-	-	-	-
PLHIGLEE_00167	2.08e-31	-	-	-	-	-	-	-	-
PLHIGLEE_00168	2.54e-59	-	-	-	-	-	-	-	-
PLHIGLEE_00172	3.34e-102	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PLHIGLEE_00173	8.85e-161	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
PLHIGLEE_00176	0.000223	-	-	-	-	-	-	-	-
PLHIGLEE_00182	1.16e-107	-	-	-	S	-	-	-	KilA-N
PLHIGLEE_00183	5.58e-45	-	-	-	-	-	-	-	-
PLHIGLEE_00184	7.95e-90	-	-	-	-	-	-	-	-
PLHIGLEE_00185	7.16e-75	-	-	-	-	-	-	-	-
PLHIGLEE_00186	9.28e-140	int8	-	-	L	-	-	-	Phage integrase family
PLHIGLEE_00187	5.8e-316	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
PLHIGLEE_00188	2.17e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PLHIGLEE_00189	9.71e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PLHIGLEE_00190	3.41e-208	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PLHIGLEE_00191	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PLHIGLEE_00192	2.8e-256	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_00193	1.38e-102	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
PLHIGLEE_00194	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
PLHIGLEE_00195	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
PLHIGLEE_00196	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PLHIGLEE_00197	2.4e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PLHIGLEE_00198	5.46e-233	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
PLHIGLEE_00199	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00200	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
PLHIGLEE_00201	2.46e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PLHIGLEE_00202	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_00203	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PLHIGLEE_00204	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PLHIGLEE_00205	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PLHIGLEE_00206	9.3e-53	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PLHIGLEE_00207	8.29e-129	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
PLHIGLEE_00208	1.53e-201	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
PLHIGLEE_00209	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
PLHIGLEE_00210	1.45e-109	-	-	-	L	ko:K07485	-	ko00000	Transposase
PLHIGLEE_00212	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PLHIGLEE_00213	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00214	1.29e-191	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
PLHIGLEE_00215	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PLHIGLEE_00217	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PLHIGLEE_00218	1.57e-54	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
PLHIGLEE_00219	3.54e-168	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
PLHIGLEE_00220	6.01e-50	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00221	1.11e-148	-	-	-	K	-	-	-	WHG domain
PLHIGLEE_00222	2.79e-118	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
PLHIGLEE_00224	4.45e-21	-	-	-	-	-	-	-	-
PLHIGLEE_00225	1.93e-126	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
PLHIGLEE_00226	3.12e-244	-	-	-	C	-	-	-	Aldo/keto reductase family
PLHIGLEE_00227	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PLHIGLEE_00228	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_00229	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
PLHIGLEE_00230	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
PLHIGLEE_00231	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PLHIGLEE_00232	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
PLHIGLEE_00233	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
PLHIGLEE_00234	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
PLHIGLEE_00235	6.15e-127	-	-	-	S	-	-	-	GtrA-like protein
PLHIGLEE_00236	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PLHIGLEE_00237	6.42e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PLHIGLEE_00238	1.87e-197	-	-	-	-	-	-	-	-
PLHIGLEE_00239	4.1e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00240	1.02e-257	-	-	-	P	-	-	-	NMT1/THI5 like
PLHIGLEE_00241	2.24e-157	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
PLHIGLEE_00243	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PLHIGLEE_00244	1.76e-125	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
PLHIGLEE_00245	2.56e-83	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
PLHIGLEE_00248	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PLHIGLEE_00249	6.48e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
PLHIGLEE_00250	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PLHIGLEE_00251	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PLHIGLEE_00252	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00254	3.36e-249	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PLHIGLEE_00255	1.02e-278	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
PLHIGLEE_00256	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PLHIGLEE_00257	2.57e-293	-	-	-	G	-	-	-	Transmembrane secretion effector
PLHIGLEE_00258	1.69e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PLHIGLEE_00259	5.12e-183	-	-	-	-	-	-	-	-
PLHIGLEE_00260	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PLHIGLEE_00261	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PLHIGLEE_00262	1.47e-221	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
PLHIGLEE_00263	7.75e-238	-	-	-	-	-	-	-	-
PLHIGLEE_00264	8.35e-232	-	-	-	-	-	-	-	-
PLHIGLEE_00265	6.2e-215	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
PLHIGLEE_00266	9.54e-153	-	-	-	S	-	-	-	CYTH
PLHIGLEE_00269	4e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
PLHIGLEE_00270	2.02e-26	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
PLHIGLEE_00271	1.34e-85	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
PLHIGLEE_00272	1.26e-197	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
PLHIGLEE_00274	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
PLHIGLEE_00275	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
PLHIGLEE_00276	1.37e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PLHIGLEE_00277	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PLHIGLEE_00278	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PLHIGLEE_00279	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PLHIGLEE_00280	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PLHIGLEE_00281	1.54e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
PLHIGLEE_00282	5.51e-239	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PLHIGLEE_00283	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
PLHIGLEE_00284	8.1e-87	-	-	-	-	-	-	-	-
PLHIGLEE_00285	8.09e-76	-	-	-	-	-	-	-	-
PLHIGLEE_00286	5.55e-211	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00287	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
PLHIGLEE_00288	9.55e-215	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
PLHIGLEE_00289	1.41e-304	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
PLHIGLEE_00290	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
PLHIGLEE_00291	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PLHIGLEE_00292	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
PLHIGLEE_00293	7.66e-275	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_00294	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PLHIGLEE_00295	1.75e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PLHIGLEE_00296	9.97e-288	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
PLHIGLEE_00298	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PLHIGLEE_00299	3.15e-151	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PLHIGLEE_00300	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
PLHIGLEE_00301	1.61e-226	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
PLHIGLEE_00302	8.22e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PLHIGLEE_00303	1.28e-254	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PLHIGLEE_00304	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
PLHIGLEE_00305	5.34e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PLHIGLEE_00306	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLHIGLEE_00307	5.79e-167	-	-	-	-	-	-	-	-
PLHIGLEE_00308	1.51e-227	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
PLHIGLEE_00309	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PLHIGLEE_00310	2.38e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
PLHIGLEE_00311	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PLHIGLEE_00312	8.16e-93	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PLHIGLEE_00315	9.21e-52	-	-	-	S	-	-	-	Parallel beta-helix repeats
PLHIGLEE_00316	5.3e-97	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
PLHIGLEE_00318	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PLHIGLEE_00319	5.45e-176	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
PLHIGLEE_00320	5.99e-237	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PLHIGLEE_00321	7.41e-190	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PLHIGLEE_00322	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
PLHIGLEE_00323	0.0	-	-	-	M	-	-	-	domain protein
PLHIGLEE_00324	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
PLHIGLEE_00325	2.96e-267	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PLHIGLEE_00326	4.61e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
PLHIGLEE_00327	2.84e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
PLHIGLEE_00329	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PLHIGLEE_00330	1.04e-169	-	-	-	M	-	-	-	Mechanosensitive ion channel
PLHIGLEE_00331	1.51e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PLHIGLEE_00332	2.87e-308	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00333	2.9e-296	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00334	7.4e-109	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
PLHIGLEE_00336	9.61e-56	-	-	-	K	-	-	-	Transcriptional regulator
PLHIGLEE_00337	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
PLHIGLEE_00338	0.00013	-	-	-	TV	ko:K05792	-	ko00000	HNH endonuclease
PLHIGLEE_00343	3.18e-16	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
PLHIGLEE_00344	2.07e-301	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PLHIGLEE_00345	1.08e-246	-	-	-	L	-	-	-	Transposase
PLHIGLEE_00346	4.26e-29	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PLHIGLEE_00347	6.85e-151	-	2.1.1.72	-	L	ko:K07319	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
PLHIGLEE_00348	2.42e-91	-	-	-	-	-	-	-	-
PLHIGLEE_00349	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
PLHIGLEE_00350	9.15e-76	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
PLHIGLEE_00351	1.13e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PLHIGLEE_00352	6.07e-309	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PLHIGLEE_00354	7.72e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
PLHIGLEE_00355	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
PLHIGLEE_00356	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
PLHIGLEE_00357	1.43e-277	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PLHIGLEE_00359	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_00360	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
PLHIGLEE_00361	4.41e-155	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
PLHIGLEE_00362	1.65e-140	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PLHIGLEE_00363	1.25e-106	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
PLHIGLEE_00364	1.37e-223	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PLHIGLEE_00365	2.27e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PLHIGLEE_00366	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PLHIGLEE_00367	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PLHIGLEE_00368	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
PLHIGLEE_00369	1.36e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
PLHIGLEE_00370	3.04e-279	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
PLHIGLEE_00371	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PLHIGLEE_00372	4.14e-212	-	-	-	P	-	-	-	Cation efflux family
PLHIGLEE_00373	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PLHIGLEE_00374	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
PLHIGLEE_00375	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
PLHIGLEE_00376	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
PLHIGLEE_00377	2.77e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PLHIGLEE_00378	3.36e-181	-	-	-	-	-	-	-	-
PLHIGLEE_00379	3.08e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PLHIGLEE_00380	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PLHIGLEE_00381	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PLHIGLEE_00382	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
PLHIGLEE_00383	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
PLHIGLEE_00385	1.65e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PLHIGLEE_00386	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PLHIGLEE_00387	8.02e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PLHIGLEE_00388	1.61e-227	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
PLHIGLEE_00391	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PLHIGLEE_00392	1.71e-271	-	-	-	-	-	-	-	-
PLHIGLEE_00394	6.19e-263	-	-	-	-	-	-	-	-
PLHIGLEE_00396	4.87e-155	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PLHIGLEE_00397	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
PLHIGLEE_00398	1e-28	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
PLHIGLEE_00399	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00400	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00401	8.57e-222	-	-	-	K	-	-	-	Putative sugar-binding domain
PLHIGLEE_00402	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PLHIGLEE_00403	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
PLHIGLEE_00404	6.29e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
PLHIGLEE_00405	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
PLHIGLEE_00406	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PLHIGLEE_00407	6.96e-200	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PLHIGLEE_00408	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PLHIGLEE_00409	7.62e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PLHIGLEE_00411	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
PLHIGLEE_00412	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PLHIGLEE_00413	2.33e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PLHIGLEE_00416	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
PLHIGLEE_00417	4.17e-260	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PLHIGLEE_00418	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
PLHIGLEE_00419	5.2e-173	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
PLHIGLEE_00420	5.91e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PLHIGLEE_00421	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
PLHIGLEE_00422	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_00423	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
PLHIGLEE_00424	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
PLHIGLEE_00425	8.16e-154	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
PLHIGLEE_00426	1.03e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
PLHIGLEE_00428	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
PLHIGLEE_00429	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
PLHIGLEE_00430	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
PLHIGLEE_00431	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
PLHIGLEE_00432	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PLHIGLEE_00433	4.93e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
PLHIGLEE_00434	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
PLHIGLEE_00435	0.0	pon1	-	-	M	-	-	-	Transglycosylase
PLHIGLEE_00436	6.1e-277	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
PLHIGLEE_00437	4.9e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
PLHIGLEE_00438	1.2e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PLHIGLEE_00439	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
PLHIGLEE_00440	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
PLHIGLEE_00441	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
PLHIGLEE_00442	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PLHIGLEE_00443	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PLHIGLEE_00444	1.62e-93	-	-	-	-	-	-	-	-
PLHIGLEE_00446	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PLHIGLEE_00447	7.7e-77	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
PLHIGLEE_00448	6.36e-38	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
PLHIGLEE_00449	3.15e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
PLHIGLEE_00450	3.36e-145	-	-	-	-	-	-	-	-
PLHIGLEE_00451	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHIGLEE_00452	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHIGLEE_00453	6.53e-125	-	-	-	T	-	-	-	Forkhead associated domain
PLHIGLEE_00454	3.7e-98	-	-	-	B	-	-	-	Belongs to the OprB family
PLHIGLEE_00455	9.56e-211	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
PLHIGLEE_00456	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
PLHIGLEE_00457	1.41e-302	-	-	-	S	-	-	-	Protein of unknown function DUF58
PLHIGLEE_00458	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
PLHIGLEE_00459	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
PLHIGLEE_00460	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
PLHIGLEE_00461	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
PLHIGLEE_00462	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
PLHIGLEE_00463	5.54e-210	-	-	-	K	-	-	-	-acetyltransferase
PLHIGLEE_00464	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
PLHIGLEE_00465	3.56e-86	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PLHIGLEE_00466	1.03e-55	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
PLHIGLEE_00467	3.83e-13	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
PLHIGLEE_00468	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PLHIGLEE_00469	5.9e-76	-	-	-	L	-	-	-	Transposase
PLHIGLEE_00470	3.34e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PLHIGLEE_00471	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLHIGLEE_00472	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PLHIGLEE_00473	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
PLHIGLEE_00474	0.0	vpr	-	-	O	-	-	-	Subtilase family
PLHIGLEE_00475	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PLHIGLEE_00476	3.18e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PLHIGLEE_00477	0.0	-	-	-	S	-	-	-	zinc finger
PLHIGLEE_00478	3.8e-139	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PLHIGLEE_00479	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
PLHIGLEE_00480	1.59e-201	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
PLHIGLEE_00481	7.96e-170	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
PLHIGLEE_00482	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
PLHIGLEE_00483	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
PLHIGLEE_00484	9.54e-234	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
PLHIGLEE_00485	4.35e-05	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PLHIGLEE_00487	4.43e-221	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
PLHIGLEE_00488	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PLHIGLEE_00489	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PLHIGLEE_00490	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
PLHIGLEE_00491	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PLHIGLEE_00493	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
PLHIGLEE_00494	3.07e-210	-	-	-	-	-	-	-	-
PLHIGLEE_00495	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
PLHIGLEE_00499	8.62e-112	-	-	-	M	-	-	-	Parallel beta-helix repeats
PLHIGLEE_00501	3.66e-117	-	-	-	K	-	-	-	MarR family
PLHIGLEE_00502	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_00503	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
PLHIGLEE_00504	2.26e-220	-	-	-	S	-	-	-	Patatin-like phospholipase
PLHIGLEE_00505	2.24e-195	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PLHIGLEE_00506	7.32e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
PLHIGLEE_00507	4.82e-147	-	-	-	S	-	-	-	Vitamin K epoxide reductase
PLHIGLEE_00508	2.09e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
PLHIGLEE_00509	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
PLHIGLEE_00510	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
PLHIGLEE_00511	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PLHIGLEE_00512	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
PLHIGLEE_00513	2.91e-193	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PLHIGLEE_00514	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
PLHIGLEE_00515	3.24e-247	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_00516	2.08e-79	-	-	-	S	-	-	-	Thiamine-binding protein
PLHIGLEE_00517	1.26e-211	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PLHIGLEE_00518	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
PLHIGLEE_00519	1.62e-110	-	-	-	-	-	-	-	-
PLHIGLEE_00520	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PLHIGLEE_00521	3.39e-200	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PLHIGLEE_00522	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
PLHIGLEE_00523	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
PLHIGLEE_00524	4.69e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PLHIGLEE_00525	8.03e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PLHIGLEE_00526	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PLHIGLEE_00527	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PLHIGLEE_00528	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
PLHIGLEE_00529	1.87e-147	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PLHIGLEE_00530	1.89e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PLHIGLEE_00532	1.25e-82	-	-	-	-	-	-	-	-
PLHIGLEE_00533	2.62e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
PLHIGLEE_00534	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PLHIGLEE_00535	4.74e-305	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
PLHIGLEE_00536	2.48e-202	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
PLHIGLEE_00537	3.82e-282	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
PLHIGLEE_00538	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PLHIGLEE_00539	4.02e-190	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
PLHIGLEE_00540	1.56e-59	-	-	-	-	-	-	-	-
PLHIGLEE_00541	8.09e-31	-	-	-	-	-	-	-	-
PLHIGLEE_00542	9.38e-13	-	-	-	-	-	-	-	-
PLHIGLEE_00543	3.79e-16	-	-	-	L	-	-	-	PFAM Integrase catalytic
PLHIGLEE_00545	1.34e-311	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
PLHIGLEE_00546	1.52e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PLHIGLEE_00547	4.85e-299	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PLHIGLEE_00548	0.0	-	-	-	I	-	-	-	acetylesterase activity
PLHIGLEE_00549	1.96e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PLHIGLEE_00550	1.03e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PLHIGLEE_00551	5.54e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
PLHIGLEE_00552	8.35e-19	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
PLHIGLEE_00553	9.99e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
PLHIGLEE_00554	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
PLHIGLEE_00555	1.07e-163	-	-	-	S	-	-	-	zinc-ribbon domain
PLHIGLEE_00556	1.57e-61	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
PLHIGLEE_00557	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
PLHIGLEE_00558	0.000175	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PLHIGLEE_00560	4.31e-259	-	-	-	K	-	-	-	WYL domain
PLHIGLEE_00561	1.35e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
PLHIGLEE_00562	2.11e-221	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
PLHIGLEE_00563	1.5e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
PLHIGLEE_00566	2.68e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
PLHIGLEE_00567	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PLHIGLEE_00568	1.85e-285	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PLHIGLEE_00569	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
PLHIGLEE_00570	5.28e-151	-	-	-	-	-	-	-	-
PLHIGLEE_00571	1.35e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PLHIGLEE_00572	8.32e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
PLHIGLEE_00573	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
PLHIGLEE_00574	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PLHIGLEE_00575	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
PLHIGLEE_00576	2e-75	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
PLHIGLEE_00577	2.12e-198	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
PLHIGLEE_00578	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
PLHIGLEE_00579	1.02e-156	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
PLHIGLEE_00580	4.62e-224	-	-	-	-	-	-	-	-
PLHIGLEE_00581	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PLHIGLEE_00582	1.13e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PLHIGLEE_00583	3.88e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLHIGLEE_00584	1.76e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PLHIGLEE_00585	5.9e-66	-	-	-	M	-	-	-	Lysin motif
PLHIGLEE_00586	3.1e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PLHIGLEE_00587	5.58e-291	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PLHIGLEE_00588	0.0	-	-	-	L	-	-	-	DNA helicase
PLHIGLEE_00589	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PLHIGLEE_00590	1.25e-261	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PLHIGLEE_00591	1.96e-97	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PLHIGLEE_00592	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
PLHIGLEE_00593	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PLHIGLEE_00594	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PLHIGLEE_00595	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLHIGLEE_00596	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PLHIGLEE_00597	1.35e-298	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
PLHIGLEE_00598	3.15e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PLHIGLEE_00599	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PLHIGLEE_00600	5.86e-232	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
PLHIGLEE_00603	3.38e-108	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PLHIGLEE_00604	3.73e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
PLHIGLEE_00605	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PLHIGLEE_00606	6.22e-285	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PLHIGLEE_00607	1.39e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PLHIGLEE_00608	1.44e-276	-	-	-	GK	-	-	-	ROK family
PLHIGLEE_00609	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PLHIGLEE_00610	4.41e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
PLHIGLEE_00611	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PLHIGLEE_00612	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00613	2.16e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00614	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PLHIGLEE_00615	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
PLHIGLEE_00616	7.52e-126	-	-	-	F	-	-	-	NUDIX domain
PLHIGLEE_00618	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
PLHIGLEE_00619	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PLHIGLEE_00620	1.46e-165	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PLHIGLEE_00621	4.4e-310	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
PLHIGLEE_00622	9.68e-293	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
PLHIGLEE_00623	1.26e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
PLHIGLEE_00624	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PLHIGLEE_00625	9.94e-149	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PLHIGLEE_00626	3.35e-84	-	-	-	-	-	-	-	-
PLHIGLEE_00627	6.49e-249	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PLHIGLEE_00628	1.13e-231	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PLHIGLEE_00630	6.06e-119	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PLHIGLEE_00631	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PLHIGLEE_00632	4.14e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
PLHIGLEE_00633	6.42e-11	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
PLHIGLEE_00634	3.07e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PLHIGLEE_00635	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
PLHIGLEE_00636	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PLHIGLEE_00637	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
PLHIGLEE_00638	4.38e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PLHIGLEE_00639	3.39e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PLHIGLEE_00640	6.08e-145	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PLHIGLEE_00641	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
PLHIGLEE_00642	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PLHIGLEE_00643	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
PLHIGLEE_00644	1.93e-210	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
PLHIGLEE_00645	8.39e-297	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
PLHIGLEE_00646	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
PLHIGLEE_00647	1.29e-109	-	-	-	-	-	-	-	-
PLHIGLEE_00648	1.68e-252	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
PLHIGLEE_00649	5.15e-246	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
PLHIGLEE_00650	2.67e-56	-	-	-	-	-	-	-	-
PLHIGLEE_00651	4.74e-236	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
PLHIGLEE_00652	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00653	5.29e-212	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
PLHIGLEE_00654	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PLHIGLEE_00655	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PLHIGLEE_00656	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PLHIGLEE_00657	1e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
PLHIGLEE_00658	2.66e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
PLHIGLEE_00659	1.87e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
PLHIGLEE_00660	1.9e-315	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PLHIGLEE_00661	2.33e-142	-	-	-	-	-	-	-	-
PLHIGLEE_00662	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PLHIGLEE_00663	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PLHIGLEE_00665	2.59e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
PLHIGLEE_00666	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
PLHIGLEE_00667	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PLHIGLEE_00668	7.86e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PLHIGLEE_00669	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PLHIGLEE_00670	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PLHIGLEE_00671	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PLHIGLEE_00672	3.67e-176	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
PLHIGLEE_00674	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
PLHIGLEE_00675	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
PLHIGLEE_00676	3.75e-207	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
PLHIGLEE_00677	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
PLHIGLEE_00678	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PLHIGLEE_00679	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
PLHIGLEE_00680	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
PLHIGLEE_00681	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
PLHIGLEE_00682	0.0	-	-	-	S	-	-	-	PGAP1-like protein
PLHIGLEE_00684	1.6e-117	-	-	-	-	-	-	-	-
PLHIGLEE_00685	2.85e-198	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
PLHIGLEE_00686	7.9e-247	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
PLHIGLEE_00687	4.37e-122	-	-	-	-	-	-	-	-
PLHIGLEE_00688	5.18e-228	-	-	-	S	-	-	-	Protein of unknown function DUF58
PLHIGLEE_00689	1.22e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
PLHIGLEE_00690	1.22e-184	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PLHIGLEE_00691	7.36e-106	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
PLHIGLEE_00692	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PLHIGLEE_00693	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
PLHIGLEE_00694	1.09e-228	-	-	-	-	-	-	-	-
PLHIGLEE_00695	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
PLHIGLEE_00696	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PLHIGLEE_00697	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PLHIGLEE_00698	7.38e-252	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
PLHIGLEE_00699	2.42e-237	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
PLHIGLEE_00700	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
PLHIGLEE_00704	2.14e-301	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
PLHIGLEE_00705	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
PLHIGLEE_00706	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PLHIGLEE_00707	2.57e-71	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_00708	5.55e-121	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
PLHIGLEE_00709	1.71e-179	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
PLHIGLEE_00710	2.4e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PLHIGLEE_00711	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00712	1.55e-251	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00713	2.49e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
PLHIGLEE_00714	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
PLHIGLEE_00715	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
PLHIGLEE_00717	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PLHIGLEE_00718	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_00719	3.98e-135	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PLHIGLEE_00721	5.64e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PLHIGLEE_00722	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
PLHIGLEE_00723	3.64e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00724	1.29e-96	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
PLHIGLEE_00725	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PLHIGLEE_00726	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
PLHIGLEE_00727	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PLHIGLEE_00728	2.75e-268	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PLHIGLEE_00729	1e-203	-	-	-	S	-	-	-	Protein conserved in bacteria
PLHIGLEE_00730	7.24e-106	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PLHIGLEE_00731	2.69e-137	-	-	-	L	-	-	-	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PLHIGLEE_00732	2.5e-39	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
PLHIGLEE_00733	1.9e-98	-	-	-	S	-	-	-	GIY-YIG catalytic domain
PLHIGLEE_00737	1.5e-15	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
PLHIGLEE_00740	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PLHIGLEE_00741	8.27e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
PLHIGLEE_00742	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PLHIGLEE_00743	2.07e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
PLHIGLEE_00744	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
PLHIGLEE_00745	7.91e-171	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
PLHIGLEE_00746	1.01e-42	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
PLHIGLEE_00747	9.83e-194	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00748	1.54e-250	-	-	-	-	-	-	-	-
PLHIGLEE_00749	6.94e-298	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
PLHIGLEE_00750	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
PLHIGLEE_00751	8.32e-263	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PLHIGLEE_00752	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PLHIGLEE_00753	2.06e-280	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
PLHIGLEE_00756	1.23e-163	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PLHIGLEE_00757	3.47e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
PLHIGLEE_00758	2.42e-194	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PLHIGLEE_00759	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PLHIGLEE_00760	9.1e-127	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PLHIGLEE_00761	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PLHIGLEE_00762	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PLHIGLEE_00763	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
PLHIGLEE_00764	6.82e-193	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
PLHIGLEE_00765	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PLHIGLEE_00766	1.2e-130	-	-	-	D	-	-	-	Septum formation initiator
PLHIGLEE_00767	3.62e-137	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
PLHIGLEE_00768	2.41e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
PLHIGLEE_00770	4.4e-126	-	-	-	-	-	-	-	-
PLHIGLEE_00771	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
PLHIGLEE_00772	8.53e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
PLHIGLEE_00773	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PLHIGLEE_00775	9.82e-95	-	-	-	-	-	-	-	-
PLHIGLEE_00776	2.77e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
PLHIGLEE_00777	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PLHIGLEE_00778	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PLHIGLEE_00779	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
PLHIGLEE_00780	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
PLHIGLEE_00781	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PLHIGLEE_00782	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
PLHIGLEE_00783	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_00784	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
PLHIGLEE_00785	2.33e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
PLHIGLEE_00786	4.46e-166	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
PLHIGLEE_00787	3.2e-93	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
PLHIGLEE_00788	1.69e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PLHIGLEE_00789	3.8e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
PLHIGLEE_00790	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PLHIGLEE_00791	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
PLHIGLEE_00792	8.94e-109	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PLHIGLEE_00793	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
PLHIGLEE_00794	1.15e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_00795	1.55e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
PLHIGLEE_00796	2.97e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PLHIGLEE_00797	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PLHIGLEE_00798	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PLHIGLEE_00799	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PLHIGLEE_00800	2.91e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
PLHIGLEE_00801	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
PLHIGLEE_00802	2e-141	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PLHIGLEE_00804	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
PLHIGLEE_00805	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PLHIGLEE_00806	1.32e-221	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
PLHIGLEE_00807	3.4e-156	-	-	-	L	-	-	-	NUDIX domain
PLHIGLEE_00808	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
PLHIGLEE_00809	3.57e-281	-	-	-	-	-	-	-	-
PLHIGLEE_00810	1.03e-141	-	-	-	-	-	-	-	-
PLHIGLEE_00811	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
PLHIGLEE_00812	9.41e-283	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
PLHIGLEE_00813	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PLHIGLEE_00814	8.97e-119	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PLHIGLEE_00815	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PLHIGLEE_00816	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
PLHIGLEE_00817	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PLHIGLEE_00818	3.55e-313	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
PLHIGLEE_00819	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PLHIGLEE_00820	4.53e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PLHIGLEE_00821	1.09e-291	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PLHIGLEE_00822	3.01e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
PLHIGLEE_00824	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PLHIGLEE_00825	5.85e-228	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
PLHIGLEE_00826	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PLHIGLEE_00827	6e-290	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PLHIGLEE_00828	2.66e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PLHIGLEE_00829	1.53e-60	-	-	-	-	-	-	-	-
PLHIGLEE_00830	3.19e-198	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
PLHIGLEE_00831	3.04e-259	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
PLHIGLEE_00832	6.34e-33	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
PLHIGLEE_00833	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
PLHIGLEE_00834	7.57e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PLHIGLEE_00835	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PLHIGLEE_00836	6.47e-64	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
PLHIGLEE_00837	2.69e-180	-	-	-	S	-	-	-	cobalamin synthesis protein
PLHIGLEE_00838	3.07e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
PLHIGLEE_00840	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
PLHIGLEE_00841	0.0	-	-	-	S	-	-	-	Putative esterase
PLHIGLEE_00842	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
PLHIGLEE_00843	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PLHIGLEE_00844	6.01e-245	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PLHIGLEE_00845	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PLHIGLEE_00846	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
PLHIGLEE_00847	9.82e-45	-	-	-	-	-	-	-	-
PLHIGLEE_00848	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHIGLEE_00849	8.74e-23	-	-	-	K	-	-	-	DNA-binding transcription factor activity
PLHIGLEE_00850	7.71e-189	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
PLHIGLEE_00851	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
PLHIGLEE_00852	1.57e-140	-	-	-	-	-	-	-	-
PLHIGLEE_00853	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
PLHIGLEE_00854	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PLHIGLEE_00855	4.7e-299	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PLHIGLEE_00856	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
PLHIGLEE_00857	1.8e-290	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
PLHIGLEE_00858	1.33e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
PLHIGLEE_00860	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PLHIGLEE_00861	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PLHIGLEE_00862	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PLHIGLEE_00863	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PLHIGLEE_00864	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
PLHIGLEE_00865	5.04e-253	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PLHIGLEE_00867	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PLHIGLEE_00868	5.01e-151	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PLHIGLEE_00869	5.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
PLHIGLEE_00870	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
PLHIGLEE_00871	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PLHIGLEE_00872	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
PLHIGLEE_00873	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_00874	0.0	-	-	-	T	-	-	-	Histidine kinase
PLHIGLEE_00875	2.17e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
PLHIGLEE_00876	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PLHIGLEE_00877	1.01e-214	-	-	-	EG	-	-	-	EamA-like transporter family
PLHIGLEE_00878	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
PLHIGLEE_00879	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PLHIGLEE_00880	2.54e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PLHIGLEE_00881	3.51e-174	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PLHIGLEE_00882	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
PLHIGLEE_00883	4.16e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLHIGLEE_00884	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PLHIGLEE_00885	1.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PLHIGLEE_00886	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
PLHIGLEE_00887	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PLHIGLEE_00888	1.97e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
PLHIGLEE_00891	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PLHIGLEE_00892	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PLHIGLEE_00893	4.2e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PLHIGLEE_00894	4.56e-142	-	-	-	-	-	-	-	-
PLHIGLEE_00895	1.06e-173	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
PLHIGLEE_00896	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
PLHIGLEE_00897	7.75e-258	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PLHIGLEE_00898	1.71e-158	-	-	-	-	-	-	-	-
PLHIGLEE_00899	1.99e-262	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PLHIGLEE_00900	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
PLHIGLEE_00901	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
PLHIGLEE_00902	1.68e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
PLHIGLEE_00903	1.65e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
PLHIGLEE_00904	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PLHIGLEE_00905	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
PLHIGLEE_00906	3.3e-300	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
PLHIGLEE_00907	1.14e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
PLHIGLEE_00908	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
PLHIGLEE_00909	3.53e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PLHIGLEE_00910	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLHIGLEE_00912	2.27e-266	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
PLHIGLEE_00913	1.78e-89	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
PLHIGLEE_00914	9.55e-66	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PLHIGLEE_00915	3.42e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PLHIGLEE_00916	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PLHIGLEE_00917	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
PLHIGLEE_00918	6.96e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
PLHIGLEE_00919	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PLHIGLEE_00920	3.51e-52	-	-	-	-	-	-	-	-
PLHIGLEE_00921	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
PLHIGLEE_00922	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PLHIGLEE_00923	5.15e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
PLHIGLEE_00924	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
PLHIGLEE_00925	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PLHIGLEE_00926	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
PLHIGLEE_00927	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PLHIGLEE_00928	6.56e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PLHIGLEE_00929	7.12e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PLHIGLEE_00932	1.49e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
PLHIGLEE_00933	6.95e-258	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PLHIGLEE_00934	1.22e-221	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PLHIGLEE_00935	6.09e-152	safC	-	-	S	-	-	-	O-methyltransferase
PLHIGLEE_00936	3.57e-235	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
PLHIGLEE_00937	4.33e-91	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
PLHIGLEE_00938	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
PLHIGLEE_00939	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
PLHIGLEE_00940	2.51e-74	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
PLHIGLEE_00941	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
PLHIGLEE_00942	3.62e-212	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PLHIGLEE_00943	1.4e-201	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PLHIGLEE_00944	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
PLHIGLEE_00945	1.63e-209	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_00946	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PLHIGLEE_00947	0.0	-	-	-	I	-	-	-	PAP2 superfamily
PLHIGLEE_00948	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_00949	0.0	-	-	-	T	-	-	-	Histidine kinase
PLHIGLEE_00950	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
PLHIGLEE_00951	3.51e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PLHIGLEE_00952	2.08e-213	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
PLHIGLEE_00953	9.38e-190	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
PLHIGLEE_00954	1.1e-238	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PLHIGLEE_00955	1.1e-235	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
PLHIGLEE_00956	8.13e-263	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PLHIGLEE_00957	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_00958	4.25e-291	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
PLHIGLEE_00959	4.5e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PLHIGLEE_00960	4.77e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PLHIGLEE_00962	1.9e-39	-	-	-	-	-	-	-	-
PLHIGLEE_00963	1.27e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PLHIGLEE_00964	9.07e-151	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
PLHIGLEE_00965	5.77e-76	-	-	-	S	-	-	-	competence protein
PLHIGLEE_00966	8.1e-11	-	-	-	-	-	-	-	-
PLHIGLEE_00970	4.52e-157	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
PLHIGLEE_00971	9.98e-49	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00972	2e-164	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_00973	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
PLHIGLEE_00974	3.15e-201	-	-	-	J	-	-	-	Methyltransferase domain
PLHIGLEE_00975	4.04e-106	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
PLHIGLEE_00976	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
PLHIGLEE_00977	4.25e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_00979	1.1e-30	-	-	-	-	-	-	-	-
PLHIGLEE_00980	8.09e-266	-	-	-	S	-	-	-	Short C-terminal domain
PLHIGLEE_00981	3.68e-111	-	-	-	S	-	-	-	Helix-turn-helix
PLHIGLEE_00982	3.35e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
PLHIGLEE_00983	2.36e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
PLHIGLEE_00984	1.72e-48	-	-	-	-	-	-	-	-
PLHIGLEE_00985	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PLHIGLEE_00986	4.32e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
PLHIGLEE_00987	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
PLHIGLEE_00989	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PLHIGLEE_00990	2.15e-151	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
PLHIGLEE_00991	1.05e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PLHIGLEE_00992	3.71e-239	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PLHIGLEE_00993	6.99e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PLHIGLEE_00994	3.21e-303	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
PLHIGLEE_00995	6.43e-110	-	-	-	K	-	-	-	AraC-like ligand binding domain
PLHIGLEE_00997	1.03e-70	-	-	-	IQ	-	-	-	oxidoreductase activity
PLHIGLEE_00998	9.25e-176	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PLHIGLEE_00999	1.43e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01000	1.35e-206	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLHIGLEE_01001	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PLHIGLEE_01002	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
PLHIGLEE_01003	4.29e-134	-	-	-	-	-	-	-	-
PLHIGLEE_01004	4.33e-259	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PLHIGLEE_01005	4.28e-274	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PLHIGLEE_01006	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
PLHIGLEE_01007	4.83e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
PLHIGLEE_01008	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PLHIGLEE_01009	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PLHIGLEE_01010	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PLHIGLEE_01012	8.68e-229	-	-	-	L	-	-	-	Phage integrase family
PLHIGLEE_01013	3.86e-82	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
PLHIGLEE_01014	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
PLHIGLEE_01015	7.41e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
PLHIGLEE_01016	2e-41	-	-	-	-	-	-	-	-
PLHIGLEE_01017	3.7e-102	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
PLHIGLEE_01018	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
PLHIGLEE_01019	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PLHIGLEE_01020	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PLHIGLEE_01021	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PLHIGLEE_01022	2.91e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PLHIGLEE_01023	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PLHIGLEE_01025	2.73e-230	-	-	-	L	-	-	-	Tetratricopeptide repeat
PLHIGLEE_01026	1.53e-242	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
PLHIGLEE_01028	5.05e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PLHIGLEE_01029	3.59e-140	-	-	-	-	-	-	-	-
PLHIGLEE_01030	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
PLHIGLEE_01031	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
PLHIGLEE_01032	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PLHIGLEE_01033	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PLHIGLEE_01034	3.05e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PLHIGLEE_01035	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PLHIGLEE_01036	6.33e-227	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01037	1.77e-162	-	-	-	S	-	-	-	ABC-2 family transporter protein
PLHIGLEE_01038	3.78e-157	-	-	-	S	-	-	-	ABC-2 family transporter protein
PLHIGLEE_01039	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
PLHIGLEE_01040	2.06e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PLHIGLEE_01041	2.19e-121	-	-	-	-	-	-	-	-
PLHIGLEE_01042	1.57e-184	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PLHIGLEE_01043	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PLHIGLEE_01045	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PLHIGLEE_01046	1.01e-87	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PLHIGLEE_01047	1.11e-175	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
PLHIGLEE_01048	1.26e-100	-	-	-	S	-	-	-	Bacterial PH domain
PLHIGLEE_01049	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
PLHIGLEE_01051	6.58e-159	-	-	-	-	-	-	-	-
PLHIGLEE_01052	6.92e-171	-	-	-	C	-	-	-	Putative TM nitroreductase
PLHIGLEE_01053	3.59e-187	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
PLHIGLEE_01054	1.94e-91	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
PLHIGLEE_01055	3.66e-187	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
PLHIGLEE_01056	1.31e-245	-	-	-	V	-	-	-	VanZ like family
PLHIGLEE_01057	8.17e-141	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PLHIGLEE_01058	2.67e-124	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PLHIGLEE_01059	1.15e-199	-	-	-	-	-	-	-	-
PLHIGLEE_01061	1.35e-127	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
PLHIGLEE_01062	3.19e-38	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
PLHIGLEE_01063	1.13e-225	-	-	-	M	-	-	-	heme binding
PLHIGLEE_01064	1.31e-103	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PLHIGLEE_01065	2.48e-160	-	-	-	-	-	-	-	-
PLHIGLEE_01066	1.15e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
PLHIGLEE_01067	5e-102	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
PLHIGLEE_01068	8.09e-235	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PLHIGLEE_01070	2.53e-28	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
PLHIGLEE_01071	1.32e-47	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
PLHIGLEE_01072	2.71e-74	-	-	-	K	-	-	-	Transcriptional regulator
PLHIGLEE_01073	6.56e-118	-	-	-	K	-	-	-	FR47-like protein
PLHIGLEE_01074	3.32e-155	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PLHIGLEE_01075	9.61e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
PLHIGLEE_01076	1.71e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PLHIGLEE_01077	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01078	2.37e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
PLHIGLEE_01079	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01080	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
PLHIGLEE_01081	9.95e-208	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
PLHIGLEE_01082	1.72e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PLHIGLEE_01083	2.64e-214	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
PLHIGLEE_01084	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PLHIGLEE_01085	1.08e-160	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
PLHIGLEE_01086	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
PLHIGLEE_01087	2.59e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PLHIGLEE_01088	6.31e-153	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
PLHIGLEE_01089	5.71e-203	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
PLHIGLEE_01090	4.23e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
PLHIGLEE_01091	2.66e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PLHIGLEE_01093	4e-168	-	-	-	M	-	-	-	Peptidase family M23
PLHIGLEE_01094	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
PLHIGLEE_01095	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
PLHIGLEE_01096	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
PLHIGLEE_01097	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
PLHIGLEE_01098	3.59e-118	-	-	-	-	-	-	-	-
PLHIGLEE_01099	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
PLHIGLEE_01100	1.05e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PLHIGLEE_01101	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PLHIGLEE_01102	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PLHIGLEE_01103	3.84e-165	-	-	-	S	-	-	-	alpha beta
PLHIGLEE_01104	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PLHIGLEE_01105	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PLHIGLEE_01106	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
PLHIGLEE_01107	2.1e-289	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PLHIGLEE_01108	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PLHIGLEE_01109	4.17e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PLHIGLEE_01110	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PLHIGLEE_01111	7.74e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PLHIGLEE_01112	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_01113	4.73e-216	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
PLHIGLEE_01114	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
PLHIGLEE_01115	1.69e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PLHIGLEE_01116	2.59e-277	-	-	-	GK	-	-	-	ROK family
PLHIGLEE_01117	1.41e-263	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
PLHIGLEE_01118	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PLHIGLEE_01119	8.31e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PLHIGLEE_01120	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
PLHIGLEE_01121	2.81e-179	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
PLHIGLEE_01122	3.04e-315	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PLHIGLEE_01123	3.53e-150	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PLHIGLEE_01124	8.93e-77	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PLHIGLEE_01125	3.39e-112	-	-	-	-	-	-	-	-
PLHIGLEE_01126	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PLHIGLEE_01127	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PLHIGLEE_01128	2.13e-230	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
PLHIGLEE_01129	3.02e-227	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PLHIGLEE_01130	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PLHIGLEE_01131	6.71e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
PLHIGLEE_01132	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PLHIGLEE_01133	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
PLHIGLEE_01134	1.23e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PLHIGLEE_01135	2.44e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PLHIGLEE_01136	3.01e-308	-	-	-	V	-	-	-	MatE
PLHIGLEE_01139	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PLHIGLEE_01140	3.12e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PLHIGLEE_01141	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PLHIGLEE_01142	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
PLHIGLEE_01143	2.42e-281	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PLHIGLEE_01144	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PLHIGLEE_01145	8.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
PLHIGLEE_01146	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PLHIGLEE_01147	4.1e-199	-	-	-	S	-	-	-	PAC2 family
PLHIGLEE_01151	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_01154	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PLHIGLEE_01155	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PLHIGLEE_01156	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
PLHIGLEE_01157	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
PLHIGLEE_01158	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PLHIGLEE_01159	1.75e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PLHIGLEE_01160	2.31e-257	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PLHIGLEE_01161	7.66e-65	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
PLHIGLEE_01162	2.26e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PLHIGLEE_01163	8.17e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PLHIGLEE_01164	9.52e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PLHIGLEE_01165	7.44e-312	-	-	-	-	-	-	-	-
PLHIGLEE_01166	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PLHIGLEE_01167	5.17e-56	-	-	-	-	-	-	-	-
PLHIGLEE_01168	9.88e-167	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PLHIGLEE_01169	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PLHIGLEE_01170	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PLHIGLEE_01171	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PLHIGLEE_01172	2.26e-210	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PLHIGLEE_01173	1.12e-246	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PLHIGLEE_01174	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
PLHIGLEE_01175	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
PLHIGLEE_01176	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
PLHIGLEE_01177	1.1e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLHIGLEE_01178	4.59e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
PLHIGLEE_01179	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
PLHIGLEE_01180	1.86e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
PLHIGLEE_01181	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
PLHIGLEE_01182	5.64e-153	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PLHIGLEE_01183	1.71e-83	-	-	-	-	-	-	-	-
PLHIGLEE_01185	1.04e-31	-	-	-	L	-	-	-	DNA integration
PLHIGLEE_01186	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PLHIGLEE_01187	3.01e-117	-	-	-	K	-	-	-	Putative zinc ribbon domain
PLHIGLEE_01189	5.69e-181	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
PLHIGLEE_01190	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
PLHIGLEE_01191	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
PLHIGLEE_01192	1.24e-68	-	-	-	-	-	-	-	-
PLHIGLEE_01193	0.0	-	-	-	K	-	-	-	WYL domain
PLHIGLEE_01194	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PLHIGLEE_01196	3.58e-115	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
PLHIGLEE_01197	7.48e-186	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PLHIGLEE_01198	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PLHIGLEE_01199	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PLHIGLEE_01200	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PLHIGLEE_01201	5.57e-120	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
PLHIGLEE_01202	1.94e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PLHIGLEE_01203	3.56e-24	-	-	-	-	-	-	-	-
PLHIGLEE_01204	1.02e-64	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
PLHIGLEE_01205	9.61e-54	-	-	-	K	-	-	-	Helix-turn-helix
PLHIGLEE_01206	4.89e-285	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
PLHIGLEE_01207	8.27e-86	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
PLHIGLEE_01208	1.13e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PLHIGLEE_01209	3.57e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PLHIGLEE_01210	1.56e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
PLHIGLEE_01211	1.39e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
PLHIGLEE_01212	8.03e-311	-	-	-	V	-	-	-	MatE
PLHIGLEE_01213	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PLHIGLEE_01214	1.76e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
PLHIGLEE_01215	1.4e-22	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_01216	6.07e-203	-	-	-	-	-	-	-	-
PLHIGLEE_01217	1.88e-249	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
PLHIGLEE_01218	2.41e-23	-	-	-	K	-	-	-	MerR family regulatory protein
PLHIGLEE_01219	1.75e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PLHIGLEE_01220	1.18e-228	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PLHIGLEE_01221	2.94e-199	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
PLHIGLEE_01222	2.31e-230	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
PLHIGLEE_01223	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PLHIGLEE_01224	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
PLHIGLEE_01225	7.76e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PLHIGLEE_01226	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
PLHIGLEE_01228	2.35e-208	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
PLHIGLEE_01229	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PLHIGLEE_01230	2.38e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
PLHIGLEE_01231	8.16e-265	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PLHIGLEE_01232	1.62e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PLHIGLEE_01233	7.01e-125	-	-	-	E	-	-	-	Rard protein
PLHIGLEE_01234	9.03e-27	-	-	-	-	-	-	-	-
PLHIGLEE_01235	2.42e-236	-	-	-	L	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
PLHIGLEE_01237	5.64e-199	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
PLHIGLEE_01238	0.0	-	-	-	O	-	-	-	Subtilase family
PLHIGLEE_01239	0.0	-	-	-	L	-	-	-	helicase
PLHIGLEE_01240	7.94e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
PLHIGLEE_01241	7.72e-300	mod	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
PLHIGLEE_01242	0.0	res	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
PLHIGLEE_01243	5.51e-164	-	-	-	-	-	-	-	-
PLHIGLEE_01244	1.35e-38	-	-	-	-	ko:K07485	-	ko00000	-
PLHIGLEE_01245	6.8e-206	-	-	-	L	ko:K07485	-	ko00000	Transposase
PLHIGLEE_01246	1.3e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PLHIGLEE_01247	7.67e-149	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
PLHIGLEE_01248	6.29e-192	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
PLHIGLEE_01249	4.56e-209	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01250	1.95e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
PLHIGLEE_01251	5.23e-107	-	-	-	-	-	-	-	-
PLHIGLEE_01252	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PLHIGLEE_01253	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
PLHIGLEE_01254	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
PLHIGLEE_01255	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
PLHIGLEE_01256	3.3e-312	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
PLHIGLEE_01257	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PLHIGLEE_01258	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PLHIGLEE_01259	4.63e-175	-	-	-	S	-	-	-	UPF0126 domain
PLHIGLEE_01260	1.31e-147	-	-	-	T	-	-	-	RNA ligase
PLHIGLEE_01261	1.58e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
PLHIGLEE_01262	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PLHIGLEE_01263	2.09e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
PLHIGLEE_01264	9.94e-306	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PLHIGLEE_01265	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
PLHIGLEE_01266	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
PLHIGLEE_01267	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
PLHIGLEE_01268	1.45e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PLHIGLEE_01269	0.0	corC	-	-	S	-	-	-	CBS domain
PLHIGLEE_01270	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PLHIGLEE_01271	4.28e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
PLHIGLEE_01272	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PLHIGLEE_01273	6.24e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PLHIGLEE_01275	2.08e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
PLHIGLEE_01276	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PLHIGLEE_01277	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PLHIGLEE_01278	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PLHIGLEE_01279	1.21e-304	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PLHIGLEE_01280	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PLHIGLEE_01281	4.84e-297	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
PLHIGLEE_01282	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
PLHIGLEE_01283	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PLHIGLEE_01284	1.31e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
PLHIGLEE_01285	3.46e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_01286	1.37e-137	-	-	-	-	-	-	-	-
PLHIGLEE_01287	2.27e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
PLHIGLEE_01288	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PLHIGLEE_01289	1.57e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PLHIGLEE_01290	5.3e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
PLHIGLEE_01291	4.03e-250	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PLHIGLEE_01292	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PLHIGLEE_01293	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PLHIGLEE_01294	7.33e-50	-	-	-	-	-	-	-	-
PLHIGLEE_01295	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
PLHIGLEE_01296	1.53e-173	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
PLHIGLEE_01297	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PLHIGLEE_01298	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PLHIGLEE_01299	2.83e-174	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_01300	3.78e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PLHIGLEE_01301	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
PLHIGLEE_01302	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PLHIGLEE_01303	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PLHIGLEE_01304	1.54e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PLHIGLEE_01305	4.79e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
PLHIGLEE_01307	1.25e-54	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PLHIGLEE_01309	4.2e-145	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
PLHIGLEE_01310	2.77e-54	-	-	-	-	-	-	-	-
PLHIGLEE_01311	2.32e-32	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
PLHIGLEE_01312	1.95e-221	tnp3521a2	-	-	L	-	-	-	Integrase core domain
PLHIGLEE_01313	9.69e-59	-	-	-	L	ko:K07483	-	ko00000	Transposase
PLHIGLEE_01314	7.23e-85	-	-	-	D	-	-	-	MobA/MobL family
PLHIGLEE_01315	8.14e-117	-	-	-	-	-	-	-	-
PLHIGLEE_01317	1.39e-257	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
PLHIGLEE_01318	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PLHIGLEE_01319	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PLHIGLEE_01320	2.77e-290	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PLHIGLEE_01321	8.42e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01322	1.83e-58	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
PLHIGLEE_01323	1.45e-298	-	-	-	T	-	-	-	Histidine kinase
PLHIGLEE_01324	1.54e-153	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_01325	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
PLHIGLEE_01326	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
PLHIGLEE_01327	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PLHIGLEE_01328	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PLHIGLEE_01330	3.68e-68	-	-	-	-	-	-	-	-
PLHIGLEE_01331	1.46e-37	-	-	-	-	-	-	-	-
PLHIGLEE_01332	3.98e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
PLHIGLEE_01334	6.9e-158	-	-	-	-	-	-	-	-
PLHIGLEE_01335	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
PLHIGLEE_01336	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
PLHIGLEE_01337	1.39e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PLHIGLEE_01338	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PLHIGLEE_01339	9.85e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
PLHIGLEE_01340	6.39e-173	-	-	-	L	-	-	-	Phage integrase family
PLHIGLEE_01342	2.08e-239	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLHIGLEE_01343	1.5e-197	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01344	9.32e-182	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
PLHIGLEE_01345	5.04e-207	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_01346	1.41e-217	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PLHIGLEE_01347	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
PLHIGLEE_01348	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PLHIGLEE_01349	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PLHIGLEE_01350	1.34e-81	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
PLHIGLEE_01351	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01352	1.79e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
PLHIGLEE_01353	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
PLHIGLEE_01354	2.47e-26	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PLHIGLEE_01355	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
PLHIGLEE_01357	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PLHIGLEE_01358	4.8e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PLHIGLEE_01359	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
PLHIGLEE_01360	6.18e-179	hflK	-	-	O	-	-	-	prohibitin homologues
PLHIGLEE_01361	8.6e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
PLHIGLEE_01362	9.77e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
PLHIGLEE_01363	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
PLHIGLEE_01364	5.53e-285	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PLHIGLEE_01365	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01366	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PLHIGLEE_01367	1.74e-118	-	-	-	K	-	-	-	acetyltransferase
PLHIGLEE_01368	2.16e-103	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PLHIGLEE_01369	1.04e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
PLHIGLEE_01370	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
PLHIGLEE_01371	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
PLHIGLEE_01372	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
PLHIGLEE_01373	2.65e-194	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PLHIGLEE_01374	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
PLHIGLEE_01375	6.9e-157	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
PLHIGLEE_01376	5.42e-219	-	-	-	-	-	-	-	-
PLHIGLEE_01377	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PLHIGLEE_01379	0.0	-	-	-	L	-	-	-	PIF1-like helicase
PLHIGLEE_01380	1.11e-202	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PLHIGLEE_01381	3.71e-154	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PLHIGLEE_01382	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
PLHIGLEE_01383	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PLHIGLEE_01384	1.06e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
PLHIGLEE_01385	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
PLHIGLEE_01386	1.11e-79	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
PLHIGLEE_01387	9.44e-234	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PLHIGLEE_01388	1.17e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PLHIGLEE_01389	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
PLHIGLEE_01391	3.38e-252	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
PLHIGLEE_01392	2.74e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
PLHIGLEE_01393	9.51e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
PLHIGLEE_01394	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
PLHIGLEE_01395	1.52e-145	-	-	-	-	-	-	-	-
PLHIGLEE_01396	2.66e-217	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
PLHIGLEE_01397	7.95e-189	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PLHIGLEE_01398	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
PLHIGLEE_01399	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
PLHIGLEE_01400	2.85e-05	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_01401	1.87e-182	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PLHIGLEE_01402	7.41e-191	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
PLHIGLEE_01404	6.46e-37	-	-	-	L	-	-	-	Transposase
PLHIGLEE_01405	1.05e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01406	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
PLHIGLEE_01407	8.66e-16	-	-	-	EGP	-	-	-	Major facilitator superfamily
PLHIGLEE_01409	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PLHIGLEE_01410	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
PLHIGLEE_01411	1.58e-72	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
PLHIGLEE_01412	1.7e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PLHIGLEE_01413	9.14e-146	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PLHIGLEE_01415	3.61e-65	-	-	-	S	-	-	-	DUF218 domain
PLHIGLEE_01416	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
PLHIGLEE_01417	4.32e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PLHIGLEE_01419	1.76e-161	-	-	-	-	-	-	-	-
PLHIGLEE_01420	2.59e-73	-	-	-	M	-	-	-	domain, Protein
PLHIGLEE_01422	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
PLHIGLEE_01423	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
PLHIGLEE_01424	2.66e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
PLHIGLEE_01425	2.35e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
PLHIGLEE_01426	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PLHIGLEE_01427	3.91e-211	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PLHIGLEE_01428	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
PLHIGLEE_01429	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PLHIGLEE_01430	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PLHIGLEE_01431	2.45e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PLHIGLEE_01432	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
PLHIGLEE_01433	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PLHIGLEE_01434	4.56e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PLHIGLEE_01435	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
PLHIGLEE_01436	0.0	-	-	-	S	-	-	-	AI-2E family transporter
PLHIGLEE_01437	1.89e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PLHIGLEE_01438	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
PLHIGLEE_01441	4.75e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
PLHIGLEE_01442	1.14e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PLHIGLEE_01443	1.16e-196	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PLHIGLEE_01445	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
PLHIGLEE_01446	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01447	8.2e-118	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
PLHIGLEE_01448	1.91e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PLHIGLEE_01449	1.71e-302	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PLHIGLEE_01450	5.05e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PLHIGLEE_01451	9.49e-138	-	-	-	-	-	-	-	-
PLHIGLEE_01452	7.07e-231	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
PLHIGLEE_01453	6.72e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_01454	4.6e-234	-	-	-	-	-	-	-	-
PLHIGLEE_01455	2e-09	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PLHIGLEE_01456	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PLHIGLEE_01457	7.89e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
PLHIGLEE_01458	5.06e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_01459	6.63e-52	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
PLHIGLEE_01460	4.43e-250	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PLHIGLEE_01461	1.58e-122	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
PLHIGLEE_01462	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
PLHIGLEE_01463	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PLHIGLEE_01464	5.29e-95	-	-	-	O	-	-	-	OsmC-like protein
PLHIGLEE_01465	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
PLHIGLEE_01466	5.95e-147	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PLHIGLEE_01467	2.48e-230	-	-	-	S	-	-	-	CHAP domain
PLHIGLEE_01468	3.82e-277	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PLHIGLEE_01469	4.6e-53	-	-	-	-	-	-	-	-
PLHIGLEE_01470	6.51e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PLHIGLEE_01471	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PLHIGLEE_01473	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PLHIGLEE_01474	2.89e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
PLHIGLEE_01475	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PLHIGLEE_01477	6.39e-279	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
PLHIGLEE_01478	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
PLHIGLEE_01479	9.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
PLHIGLEE_01480	5.79e-199	-	-	-	-	-	-	-	-
PLHIGLEE_01481	0.0	pspC	-	-	KT	-	-	-	PspC domain
PLHIGLEE_01482	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
PLHIGLEE_01483	1.18e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PLHIGLEE_01484	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PLHIGLEE_01486	1.43e-181	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
PLHIGLEE_01487	7.54e-240	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
PLHIGLEE_01488	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PLHIGLEE_01489	4.52e-123	-	-	-	-	-	-	-	-
PLHIGLEE_01491	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
PLHIGLEE_01493	2.32e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PLHIGLEE_01494	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
PLHIGLEE_01495	1.37e-271	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PLHIGLEE_01496	5.06e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PLHIGLEE_01497	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
PLHIGLEE_01499	1.69e-59	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
PLHIGLEE_01500	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PLHIGLEE_01501	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PLHIGLEE_01502	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
PLHIGLEE_01503	4.34e-261	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PLHIGLEE_01504	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PLHIGLEE_01505	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
PLHIGLEE_01506	8.06e-141	-	-	-	-	-	-	-	-
PLHIGLEE_01507	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PLHIGLEE_01508	1.78e-304	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
PLHIGLEE_01509	2.73e-300	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PLHIGLEE_01510	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PLHIGLEE_01511	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PLHIGLEE_01512	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PLHIGLEE_01513	4.44e-225	-	-	-	-	-	-	-	-
PLHIGLEE_01514	2.09e-45	-	-	-	-	-	-	-	-
PLHIGLEE_01516	9.14e-198	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
PLHIGLEE_01517	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
PLHIGLEE_01518	2.76e-219	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PLHIGLEE_01519	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
PLHIGLEE_01520	3.77e-95	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PLHIGLEE_01521	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLHIGLEE_01522	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PLHIGLEE_01523	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PLHIGLEE_01524	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PLHIGLEE_01525	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PLHIGLEE_01526	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PLHIGLEE_01527	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PLHIGLEE_01528	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
PLHIGLEE_01529	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
PLHIGLEE_01530	1.18e-148	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PLHIGLEE_01531	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PLHIGLEE_01532	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PLHIGLEE_01533	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PLHIGLEE_01534	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PLHIGLEE_01535	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PLHIGLEE_01536	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PLHIGLEE_01537	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PLHIGLEE_01538	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PLHIGLEE_01539	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PLHIGLEE_01540	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PLHIGLEE_01541	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PLHIGLEE_01542	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PLHIGLEE_01543	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PLHIGLEE_01544	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PLHIGLEE_01545	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PLHIGLEE_01546	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PLHIGLEE_01547	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PLHIGLEE_01548	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PLHIGLEE_01549	3e-172	-	-	-	S	-	-	-	YwiC-like protein
PLHIGLEE_01550	1.36e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PLHIGLEE_01551	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PLHIGLEE_01552	5.03e-297	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
PLHIGLEE_01553	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
PLHIGLEE_01554	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PLHIGLEE_01555	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PLHIGLEE_01556	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
PLHIGLEE_01557	1.25e-156	-	-	-	-	-	-	-	-
PLHIGLEE_01558	4e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
PLHIGLEE_01559	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
PLHIGLEE_01561	1.89e-306	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PLHIGLEE_01562	4.71e-284	dapC	-	-	E	-	-	-	Aminotransferase class I and II
PLHIGLEE_01563	5.9e-80	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
PLHIGLEE_01564	2.9e-275	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PLHIGLEE_01565	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
PLHIGLEE_01569	1.8e-56	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
PLHIGLEE_01570	4.97e-170	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PLHIGLEE_01571	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PLHIGLEE_01572	5.53e-267	-	-	-	-	-	-	-	-
PLHIGLEE_01573	9.98e-121	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PLHIGLEE_01574	3.43e-155	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
PLHIGLEE_01575	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
PLHIGLEE_01576	2.1e-141	-	-	-	NO	-	-	-	SAF
PLHIGLEE_01577	2.87e-56	-	-	-	-	-	-	-	-
PLHIGLEE_01578	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
PLHIGLEE_01579	0.0	-	-	-	T	-	-	-	Forkhead associated domain
PLHIGLEE_01581	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PLHIGLEE_01582	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PLHIGLEE_01583	5.07e-236	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
PLHIGLEE_01584	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
PLHIGLEE_01586	2.41e-312	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
PLHIGLEE_01588	3.1e-205	-	-	-	S	-	-	-	Protein conserved in bacteria
PLHIGLEE_01589	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PLHIGLEE_01590	3.82e-233	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
PLHIGLEE_01591	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PLHIGLEE_01592	1.71e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
PLHIGLEE_01593	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PLHIGLEE_01594	1.28e-311	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
PLHIGLEE_01595	7.68e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PLHIGLEE_01596	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PLHIGLEE_01597	1.71e-138	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PLHIGLEE_01598	2.13e-310	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PLHIGLEE_01599	1.14e-276	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PLHIGLEE_01600	3.03e-233	-	-	-	L	-	-	-	Excalibur calcium-binding domain
PLHIGLEE_01601	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PLHIGLEE_01602	2.51e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
PLHIGLEE_01603	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PLHIGLEE_01604	9.04e-186	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PLHIGLEE_01605	8.18e-243	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
PLHIGLEE_01606	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
PLHIGLEE_01607	1.53e-118	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
PLHIGLEE_01608	1.14e-212	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
PLHIGLEE_01609	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PLHIGLEE_01610	3.47e-128	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
PLHIGLEE_01611	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHIGLEE_01612	1.03e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLHIGLEE_01613	6.87e-92	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
PLHIGLEE_01614	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PLHIGLEE_01615	2.63e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PLHIGLEE_01616	2.19e-56	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
PLHIGLEE_01617	3.32e-194	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
PLHIGLEE_01618	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PLHIGLEE_01619	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PLHIGLEE_01620	1.43e-151	-	-	-	-	-	-	-	-
PLHIGLEE_01621	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
PLHIGLEE_01623	4.39e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
PLHIGLEE_01624	6.53e-127	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PLHIGLEE_01625	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
PLHIGLEE_01626	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
PLHIGLEE_01627	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
PLHIGLEE_01628	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PLHIGLEE_01629	8.21e-197	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
PLHIGLEE_01630	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_01631	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
PLHIGLEE_01632	1.83e-167	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PLHIGLEE_01633	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PLHIGLEE_01634	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PLHIGLEE_01635	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PLHIGLEE_01636	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PLHIGLEE_01637	2.81e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLHIGLEE_01638	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PLHIGLEE_01639	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLHIGLEE_01641	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PLHIGLEE_01642	2.94e-265	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLHIGLEE_01644	2.17e-47	-	-	-	-	-	-	-	-
PLHIGLEE_01645	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
PLHIGLEE_01646	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
PLHIGLEE_01647	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PLHIGLEE_01649	2.85e-134	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PLHIGLEE_01650	5.6e-170	-	-	-	-	-	-	-	-
PLHIGLEE_01651	5.57e-175	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
PLHIGLEE_01652	2.07e-162	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PLHIGLEE_01653	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PLHIGLEE_01654	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PLHIGLEE_01655	0.0	-	-	-	S	-	-	-	domain protein
PLHIGLEE_01656	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
PLHIGLEE_01657	2.2e-117	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
PLHIGLEE_01658	4.84e-297	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
PLHIGLEE_01659	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PLHIGLEE_01660	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
PLHIGLEE_01661	1.32e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
PLHIGLEE_01662	1.61e-250	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PLHIGLEE_01663	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLHIGLEE_01664	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PLHIGLEE_01665	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLHIGLEE_01666	1.28e-106	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_01667	2.72e-54	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_01668	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
PLHIGLEE_01669	2.47e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PLHIGLEE_01670	2.51e-298	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
PLHIGLEE_01671	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
PLHIGLEE_01672	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
PLHIGLEE_01673	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
PLHIGLEE_01674	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
PLHIGLEE_01675	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
PLHIGLEE_01676	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
PLHIGLEE_01677	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PLHIGLEE_01678	0.0	dinF	-	-	V	-	-	-	MatE
PLHIGLEE_01679	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
PLHIGLEE_01680	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
PLHIGLEE_01681	3.63e-306	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
PLHIGLEE_01682	6.66e-281	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PLHIGLEE_01684	1.17e-172	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PLHIGLEE_01685	6.85e-255	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
PLHIGLEE_01686	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
PLHIGLEE_01687	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
PLHIGLEE_01688	1.92e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PLHIGLEE_01689	7.12e-109	-	-	-	-	-	-	-	-
PLHIGLEE_01690	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
PLHIGLEE_01691	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_01692	2.29e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PLHIGLEE_01693	4.77e-91	-	-	-	E	-	-	-	IrrE N-terminal-like domain
PLHIGLEE_01695	4.74e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PLHIGLEE_01696	1.32e-306	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PLHIGLEE_01697	2.24e-103	-	-	-	-	-	-	-	-
PLHIGLEE_01698	5.23e-45	-	-	-	Q	-	-	-	phosphatase activity
PLHIGLEE_01699	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
PLHIGLEE_01700	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PLHIGLEE_01701	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PLHIGLEE_01702	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PLHIGLEE_01703	7.95e-87	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PLHIGLEE_01704	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
PLHIGLEE_01705	8.08e-103	-	-	-	S	-	-	-	FMN_bind
PLHIGLEE_01706	1.1e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PLHIGLEE_01707	4.2e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PLHIGLEE_01708	6.51e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PLHIGLEE_01709	1.76e-295	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
PLHIGLEE_01710	2.37e-146	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
PLHIGLEE_01711	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
PLHIGLEE_01712	8.33e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
PLHIGLEE_01713	2.9e-256	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PLHIGLEE_01714	5.58e-48	-	-	-	S	-	-	-	Fic/DOC family
PLHIGLEE_01716	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PLHIGLEE_01717	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
PLHIGLEE_01718	1.14e-256	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PLHIGLEE_01719	1.22e-271	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PLHIGLEE_01720	2.08e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PLHIGLEE_01721	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PLHIGLEE_01722	1.87e-250	-	-	-	I	-	-	-	PAP2 superfamily
PLHIGLEE_01723	0.0	-	-	-	M	-	-	-	PA domain
PLHIGLEE_01724	2.92e-129	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
PLHIGLEE_01725	2.56e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PLHIGLEE_01726	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
PLHIGLEE_01727	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLHIGLEE_01728	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PLHIGLEE_01729	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
PLHIGLEE_01730	1.77e-148	-	-	-	-	-	-	-	-
PLHIGLEE_01731	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PLHIGLEE_01733	2.36e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
PLHIGLEE_01734	2.68e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
PLHIGLEE_01735	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PLHIGLEE_01736	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
PLHIGLEE_01737	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
PLHIGLEE_01738	1.04e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
PLHIGLEE_01739	3.25e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
PLHIGLEE_01740	3.67e-20	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
PLHIGLEE_01742	1.02e-154	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
PLHIGLEE_01743	1.93e-243	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
PLHIGLEE_01744	8.79e-167	-	-	-	D	-	-	-	bacterial-type flagellum organization
PLHIGLEE_01745	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PLHIGLEE_01746	5.71e-257	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
PLHIGLEE_01747	5.26e-130	-	-	-	-	-	-	-	-
PLHIGLEE_01749	2.6e-37	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PLHIGLEE_01750	1.65e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
PLHIGLEE_01751	0.0	-	-	-	-	-	-	-	-
PLHIGLEE_01752	2.41e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
PLHIGLEE_01753	6.46e-210	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PLHIGLEE_01754	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PLHIGLEE_01755	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
PLHIGLEE_01756	0.0	-	-	-	V	-	-	-	ABC transporter permease
PLHIGLEE_01757	1.03e-272	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PLHIGLEE_01758	8.25e-176	-	-	-	T	ko:K06950	-	ko00000	HD domain
PLHIGLEE_01759	2.98e-214	-	-	-	S	-	-	-	Glutamine amidotransferase domain
PLHIGLEE_01760	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PLHIGLEE_01761	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
PLHIGLEE_01762	0.0	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
PLHIGLEE_01764	1.29e-96	-	-	-	K	-	-	-	Transcriptional regulator
PLHIGLEE_01765	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLHIGLEE_01766	1.14e-171	-	-	-	-	-	-	-	-
PLHIGLEE_01767	1.6e-83	-	-	-	-	-	-	-	-
PLHIGLEE_01768	7.3e-219	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PLHIGLEE_01769	1.05e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PLHIGLEE_01771	2.47e-179	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
PLHIGLEE_01772	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
PLHIGLEE_01773	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
PLHIGLEE_01774	9.12e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
PLHIGLEE_01775	2.72e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
PLHIGLEE_01776	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PLHIGLEE_01777	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PLHIGLEE_01778	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
PLHIGLEE_01779	9.58e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_01782	1.02e-171	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
PLHIGLEE_01783	9.49e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
PLHIGLEE_01784	3.27e-183	nfrA	-	-	C	-	-	-	Nitroreductase family
PLHIGLEE_01785	2.45e-61	-	-	-	-	-	-	-	-
PLHIGLEE_01786	1.7e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
PLHIGLEE_01787	2.67e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
PLHIGLEE_01788	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PLHIGLEE_01789	2.31e-185	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
PLHIGLEE_01790	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
PLHIGLEE_01791	1.73e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
PLHIGLEE_01792	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
PLHIGLEE_01793	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
PLHIGLEE_01795	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLHIGLEE_01796	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
PLHIGLEE_01797	1.57e-199	-	-	-	-	-	-	-	-
PLHIGLEE_01798	6.1e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PLHIGLEE_01799	1.49e-316	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PLHIGLEE_01800	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
PLHIGLEE_01801	1.14e-134	-	-	-	L	-	-	-	Helix-turn-helix domain
PLHIGLEE_01802	1.54e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PLHIGLEE_01803	7.97e-223	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PLHIGLEE_01804	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
PLHIGLEE_01805	7.42e-201	-	-	-	O	-	-	-	Thioredoxin
PLHIGLEE_01807	4.84e-280	rpfB	-	-	S	ko:K21688	-	ko00000	G5
PLHIGLEE_01808	6.28e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PLHIGLEE_01809	5.38e-213	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PLHIGLEE_01810	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
PLHIGLEE_01811	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
PLHIGLEE_01812	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
PLHIGLEE_01813	0.0	-	-	-	M	-	-	-	Conserved repeat domain
PLHIGLEE_01814	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
PLHIGLEE_01815	2.77e-258	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PLHIGLEE_01816	9.38e-311	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PLHIGLEE_01817	1.05e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PLHIGLEE_01818	2.59e-162	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PLHIGLEE_01819	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
PLHIGLEE_01820	2.11e-227	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
PLHIGLEE_01821	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PLHIGLEE_01822	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PLHIGLEE_01823	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PLHIGLEE_01824	4.6e-307	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PLHIGLEE_01825	2.63e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
PLHIGLEE_01826	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PLHIGLEE_01827	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PLHIGLEE_01828	2.04e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
PLHIGLEE_01831	4.22e-206	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
PLHIGLEE_01832	1.67e-154	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
PLHIGLEE_01835	3.21e-16	-	-	-	-	-	-	-	-