ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEKLCKCI_00001 1.72e-18 - - - - - - - -
NEKLCKCI_00002 2.28e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
NEKLCKCI_00003 7.95e-189 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEKLCKCI_00004 0.0 - - - JKL - - - helicase superfamily c-terminal domain
NEKLCKCI_00005 1.23e-210 - - - EG - - - EamA-like transporter family
NEKLCKCI_00006 1.09e-05 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00007 1.5e-188 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEKLCKCI_00008 2.89e-188 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NEKLCKCI_00010 4.95e-269 - - - S - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_00011 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
NEKLCKCI_00012 6.76e-49 - - - C - - - Aldo/keto reductase family
NEKLCKCI_00013 1.74e-66 - - - EGP - - - Major facilitator superfamily
NEKLCKCI_00014 8.66e-16 - - - EGP - - - Major facilitator superfamily
NEKLCKCI_00016 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKLCKCI_00017 0.0 - - - S - - - ATPases associated with a variety of cellular activities
NEKLCKCI_00018 4.9e-76 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
NEKLCKCI_00019 5.09e-202 - - - I - - - alpha/beta hydrolase fold
NEKLCKCI_00020 4.04e-149 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
NEKLCKCI_00022 7.29e-65 - - - S - - - DUF218 domain
NEKLCKCI_00023 1.27e-22 - - - S - - - Protein of unknown function (DUF979)
NEKLCKCI_00024 3.7e-149 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEKLCKCI_00026 4.33e-162 - - - - - - - -
NEKLCKCI_00027 1.17e-224 - - - M - - - domain, Protein
NEKLCKCI_00028 8.64e-24 - - - M - - - domain, Protein
NEKLCKCI_00029 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
NEKLCKCI_00030 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
NEKLCKCI_00031 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
NEKLCKCI_00032 7.2e-102 - - - S - - - Protein of unknown function (DUF3180)
NEKLCKCI_00033 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEKLCKCI_00034 3.21e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEKLCKCI_00035 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NEKLCKCI_00036 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEKLCKCI_00037 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEKLCKCI_00038 9.99e-269 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEKLCKCI_00039 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
NEKLCKCI_00040 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEKLCKCI_00041 2.64e-214 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00042 3.97e-295 - - - M - - - Glycosyl transferase family 21
NEKLCKCI_00043 0.0 - - - S - - - AI-2E family transporter
NEKLCKCI_00044 5.42e-227 - - - M - - - Glycosyltransferase like family 2
NEKLCKCI_00045 6.04e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NEKLCKCI_00046 5.97e-143 - - - S ko:K07090 - ko00000 membrane transporter protein
NEKLCKCI_00049 3.5e-104 - - - S - - - Domain of unknown function (DUF4190)
NEKLCKCI_00050 2.29e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEKLCKCI_00051 9.7e-223 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEKLCKCI_00053 2.46e-27 - - - S - - - Helix-turn-helix domain
NEKLCKCI_00054 8.51e-26 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
NEKLCKCI_00055 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEKLCKCI_00056 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NEKLCKCI_00057 1.53e-113 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NEKLCKCI_00058 2.73e-231 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NEKLCKCI_00059 1.41e-301 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEKLCKCI_00060 5.05e-153 - - - K - - - Transcriptional regulatory protein, C terminal
NEKLCKCI_00061 3.34e-131 - - - - - - - -
NEKLCKCI_00062 1.15e-55 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
NEKLCKCI_00063 4.81e-56 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEKLCKCI_00064 3.34e-225 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEKLCKCI_00065 2.95e-142 cas4 3.1.12.1 - L ko:K07464,ko:K15342 - ko00000,ko01000,ko02048,ko03400 Domain of unknown function DUF83
NEKLCKCI_00066 1.9e-189 - - - L ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
NEKLCKCI_00067 1.97e-304 - - - S - - - CRISPR-associated protein (Cas_Csd1)
NEKLCKCI_00068 4.71e-133 cas5d - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
NEKLCKCI_00069 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 DEAD-like helicases superfamily
NEKLCKCI_00070 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEKLCKCI_00071 2.38e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NEKLCKCI_00072 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
NEKLCKCI_00073 1.77e-178 hflK - - O - - - prohibitin homologues
NEKLCKCI_00074 4.45e-311 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEKLCKCI_00075 5.45e-299 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEKLCKCI_00076 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
NEKLCKCI_00077 1.66e-286 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NEKLCKCI_00078 6.34e-134 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00079 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEKLCKCI_00080 1.21e-72 - - - K - - - MerR, DNA binding
NEKLCKCI_00081 1.73e-248 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
NEKLCKCI_00082 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
NEKLCKCI_00083 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
NEKLCKCI_00084 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NEKLCKCI_00085 2.65e-194 - - - S - - - Short repeat of unknown function (DUF308)
NEKLCKCI_00086 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
NEKLCKCI_00087 6.9e-157 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NEKLCKCI_00088 5.42e-219 - - - - - - - -
NEKLCKCI_00089 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEKLCKCI_00091 0.0 - - - L - - - PIF1-like helicase
NEKLCKCI_00092 1.58e-202 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKLCKCI_00093 1.91e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NEKLCKCI_00094 5.15e-147 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NEKLCKCI_00095 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
NEKLCKCI_00096 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEKLCKCI_00097 7.46e-261 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
NEKLCKCI_00098 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
NEKLCKCI_00099 1.11e-79 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
NEKLCKCI_00100 9.44e-234 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEKLCKCI_00101 1.17e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEKLCKCI_00102 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NEKLCKCI_00104 3.61e-122 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
NEKLCKCI_00105 1.45e-86 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
NEKLCKCI_00106 2.74e-209 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
NEKLCKCI_00107 9.51e-240 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NEKLCKCI_00108 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
NEKLCKCI_00109 1.22e-114 - - - - - - - -
NEKLCKCI_00110 7e-133 tnp3521a2 - - L - - - Integrase core domain
NEKLCKCI_00111 4.14e-193 - - - K - - - Transposase IS116 IS110 IS902
NEKLCKCI_00112 1.1e-19 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NEKLCKCI_00113 1.73e-272 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
NEKLCKCI_00114 0.0 - - - M - - - Glycosyl transferase family 8
NEKLCKCI_00115 4.9e-179 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NEKLCKCI_00116 7.98e-310 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00117 0.0 - - - M - - - hydrolase, family 25
NEKLCKCI_00118 6.7e-158 - - - L - - - Protein of unknown function (DUF1524)
NEKLCKCI_00119 4.82e-196 - - - M - - - Putative cell wall binding repeat 2
NEKLCKCI_00120 0.0 - - - L - - - Transposase
NEKLCKCI_00121 1.7e-162 - - - L - - - IstB-like ATP binding protein
NEKLCKCI_00122 0.0 - - - M - - - Belongs to the glycosyl hydrolase 43 family
NEKLCKCI_00123 8.3e-223 - - - M - - - Glycosyl transferase, family 2
NEKLCKCI_00124 0.0 - - - M - - - Glycosyl transferase family 8
NEKLCKCI_00125 0.0 - - - - - - - -
NEKLCKCI_00126 2.23e-152 - - - S - - - Acyltransferase family
NEKLCKCI_00127 5.6e-140 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00128 1.41e-232 - - - - - - - -
NEKLCKCI_00129 2.63e-48 - - - - - - - -
NEKLCKCI_00130 8.28e-135 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEKLCKCI_00131 1.54e-224 - - - L - - - Replication initiation factor
NEKLCKCI_00132 4.81e-30 - - - S - - - Excisionase from transposon Tn916
NEKLCKCI_00133 2.48e-217 - - - L - - - Phage integrase family
NEKLCKCI_00134 8.93e-94 - - - S - - - Acyltransferase family
NEKLCKCI_00135 4.11e-90 - - - L ko:K07485 - ko00000 Transposase
NEKLCKCI_00136 1.47e-243 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_00137 6.23e-102 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEKLCKCI_00138 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKLCKCI_00139 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEKLCKCI_00140 3.08e-177 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
NEKLCKCI_00141 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NEKLCKCI_00142 2.83e-240 - - - EG - - - EamA-like transporter family
NEKLCKCI_00143 1.37e-305 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
NEKLCKCI_00144 1.14e-122 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_00145 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NEKLCKCI_00146 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
NEKLCKCI_00147 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
NEKLCKCI_00148 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEKLCKCI_00149 1.95e-308 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NEKLCKCI_00150 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NEKLCKCI_00151 0.0 - - - S - - - Threonine/Serine exporter, ThrE
NEKLCKCI_00152 5.14e-226 - - - S - - - Amidohydrolase family
NEKLCKCI_00153 4.09e-249 - - - S - - - Protein conserved in bacteria
NEKLCKCI_00154 1.2e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKLCKCI_00155 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
NEKLCKCI_00156 2.63e-116 - - - K - - - LytTr DNA-binding domain
NEKLCKCI_00157 2.12e-102 - - - T - - - protein histidine kinase activity
NEKLCKCI_00158 5.04e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEKLCKCI_00159 4.72e-38 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEKLCKCI_00160 0.0 - - - M - - - Glycosyl hydrolases family 25
NEKLCKCI_00161 4.37e-213 - - - M - - - Glycosyl transferase family 2
NEKLCKCI_00163 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NEKLCKCI_00164 6.77e-26 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEKLCKCI_00165 8.85e-243 - - - K - - - Periplasmic binding protein domain
NEKLCKCI_00166 4.92e-159 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NEKLCKCI_00167 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NEKLCKCI_00168 1.13e-82 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
NEKLCKCI_00169 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEKLCKCI_00170 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEKLCKCI_00171 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NEKLCKCI_00172 6.69e-216 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00173 8.32e-207 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00174 1.61e-182 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
NEKLCKCI_00175 1.57e-199 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00176 1.71e-238 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEKLCKCI_00177 2e-41 - - - - - - - -
NEKLCKCI_00178 7.41e-198 - - - S - - - Domain of unknown function (DUF4357)
NEKLCKCI_00179 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
NEKLCKCI_00181 3.21e-157 - - - S - - - Psort location Cytoplasmic, score 8.96
NEKLCKCI_00182 0.0 - - - L - - - PFAM Integrase catalytic
NEKLCKCI_00183 4.85e-185 istB - - L - - - IstB-like ATP binding protein
NEKLCKCI_00184 4.22e-206 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
NEKLCKCI_00185 7.67e-91 - - - L ko:K07493 - ko00000 PFAM Transposase, Mutator family
NEKLCKCI_00186 2.92e-137 - - - L ko:K07483 - ko00000 Integrase core domain
NEKLCKCI_00187 4.31e-129 - - - K - - - cell envelope-related transcriptional attenuator
NEKLCKCI_00188 1.83e-304 - - - - - - - -
NEKLCKCI_00189 1.44e-229 - - - S ko:K21688 - ko00000 G5
NEKLCKCI_00190 2.57e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
NEKLCKCI_00191 6.71e-153 - - - F - - - Domain of unknown function (DUF4916)
NEKLCKCI_00192 5.71e-203 - - - I - - - Alpha/beta hydrolase family
NEKLCKCI_00193 7.82e-264 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NEKLCKCI_00194 0.0 - - - S - - - L,D-transpeptidase catalytic domain
NEKLCKCI_00195 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NEKLCKCI_00196 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
NEKLCKCI_00197 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
NEKLCKCI_00198 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEKLCKCI_00199 4.93e-151 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
NEKLCKCI_00200 4.67e-173 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NEKLCKCI_00201 0.0 pon1 - - M - - - Transglycosylase
NEKLCKCI_00202 8.66e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
NEKLCKCI_00203 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NEKLCKCI_00204 1.2e-179 - - - K - - - DeoR C terminal sensor domain
NEKLCKCI_00205 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
NEKLCKCI_00206 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
NEKLCKCI_00207 1.32e-308 - - - EGP - - - Sugar (and other) transporter
NEKLCKCI_00208 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NEKLCKCI_00209 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
NEKLCKCI_00210 1.62e-93 - - - - - - - -
NEKLCKCI_00212 9.1e-157 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEKLCKCI_00213 2.66e-09 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
NEKLCKCI_00214 6.87e-60 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
NEKLCKCI_00215 3.13e-237 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
NEKLCKCI_00216 1.31e-142 - - - - - - - -
NEKLCKCI_00217 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKLCKCI_00218 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKLCKCI_00219 2.66e-124 - - - T - - - Forkhead associated domain
NEKLCKCI_00220 1.64e-55 - - - B - - - Belongs to the OprB family
NEKLCKCI_00221 5.53e-210 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
NEKLCKCI_00222 0.0 - - - E - - - Transglutaminase-like superfamily
NEKLCKCI_00223 2.24e-299 - - - S - - - Protein of unknown function DUF58
NEKLCKCI_00224 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEKLCKCI_00225 0.0 - - - S - - - Fibronectin type 3 domain
NEKLCKCI_00226 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NEKLCKCI_00227 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
NEKLCKCI_00228 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
NEKLCKCI_00229 9.73e-195 - - - K - - - -acetyltransferase
NEKLCKCI_00230 0.0 - - - G - - - Major Facilitator Superfamily
NEKLCKCI_00231 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NEKLCKCI_00232 5.9e-76 - - - L - - - Transposase
NEKLCKCI_00233 1.16e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEKLCKCI_00234 6.97e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEKLCKCI_00235 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEKLCKCI_00236 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
NEKLCKCI_00237 1.89e-313 vpr - - O - - - Subtilase family
NEKLCKCI_00238 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEKLCKCI_00239 1.58e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEKLCKCI_00240 0.0 - - - S - - - zinc finger
NEKLCKCI_00241 1.95e-140 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NEKLCKCI_00242 3.64e-291 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
NEKLCKCI_00243 2.21e-47 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NEKLCKCI_00244 3.94e-170 tmp1 - - S - - - Domain of unknown function (DUF4391)
NEKLCKCI_00245 8.74e-193 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
NEKLCKCI_00246 0.0 - - - OP - - - Sulfurtransferase TusA
NEKLCKCI_00247 9.54e-234 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NEKLCKCI_00248 4.35e-05 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEKLCKCI_00250 2.98e-219 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
NEKLCKCI_00251 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEKLCKCI_00252 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEKLCKCI_00253 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
NEKLCKCI_00254 3.42e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEKLCKCI_00256 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
NEKLCKCI_00257 3.9e-213 - - - - - - - -
NEKLCKCI_00258 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
NEKLCKCI_00262 3.53e-119 - - - M - - - Parallel beta-helix repeats
NEKLCKCI_00264 4.46e-118 - - - K - - - MarR family
NEKLCKCI_00265 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00266 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NEKLCKCI_00267 2.26e-220 - - - S - - - Patatin-like phospholipase
NEKLCKCI_00268 2.24e-195 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEKLCKCI_00269 7.32e-216 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NEKLCKCI_00270 4.82e-147 - - - S - - - Vitamin K epoxide reductase
NEKLCKCI_00271 2.09e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
NEKLCKCI_00272 9.31e-44 - - - S - - - Protein of unknown function (DUF3107)
NEKLCKCI_00273 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
NEKLCKCI_00274 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEKLCKCI_00275 0.0 - - - S - - - Zincin-like metallopeptidase
NEKLCKCI_00276 2.91e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NEKLCKCI_00277 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
NEKLCKCI_00278 3.24e-247 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_00279 2.08e-79 - - - S - - - Thiamine-binding protein
NEKLCKCI_00280 7.27e-211 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEKLCKCI_00281 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
NEKLCKCI_00282 1.62e-110 - - - - - - - -
NEKLCKCI_00283 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEKLCKCI_00284 1.5e-203 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEKLCKCI_00285 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
NEKLCKCI_00286 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
NEKLCKCI_00287 4.69e-314 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEKLCKCI_00288 8.03e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEKLCKCI_00289 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEKLCKCI_00290 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
NEKLCKCI_00291 1.65e-191 - - - V - - - DivIVA protein
NEKLCKCI_00292 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEKLCKCI_00293 1.89e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEKLCKCI_00295 1.25e-82 - - - - - - - -
NEKLCKCI_00296 3.72e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NEKLCKCI_00297 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEKLCKCI_00298 3.39e-298 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
NEKLCKCI_00299 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
NEKLCKCI_00300 2.15e-284 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
NEKLCKCI_00301 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEKLCKCI_00302 1.06e-185 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
NEKLCKCI_00303 4.66e-61 - - - - - - - -
NEKLCKCI_00304 1.42e-31 - - - - - - - -
NEKLCKCI_00305 9.38e-13 - - - - - - - -
NEKLCKCI_00306 3.79e-16 - - - L - - - PFAM Integrase catalytic
NEKLCKCI_00308 7.14e-316 - - - NU - - - Tfp pilus assembly protein FimV
NEKLCKCI_00309 2.16e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEKLCKCI_00310 9.79e-299 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEKLCKCI_00311 0.0 - - - I - - - acetylesterase activity
NEKLCKCI_00312 4.82e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NEKLCKCI_00313 2.53e-198 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEKLCKCI_00314 1.65e-245 - - - S - - - Domain of unknown function (DUF1963)
NEKLCKCI_00315 1.2e-19 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NEKLCKCI_00316 1.85e-52 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NEKLCKCI_00317 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
NEKLCKCI_00318 2.09e-151 - - - S - - - zinc-ribbon domain
NEKLCKCI_00319 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
NEKLCKCI_00320 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
NEKLCKCI_00322 2.5e-258 - - - K - - - WYL domain
NEKLCKCI_00323 5.5e-199 - - - S - - - Aldo/keto reductase family
NEKLCKCI_00324 2.11e-221 dkgV - - C - - - Aldo/keto reductase family
NEKLCKCI_00325 1.5e-100 - - - S - - - Domain of unknown function (DUF4186)
NEKLCKCI_00328 2.68e-232 - - - S - - - Protein conserved in bacteria
NEKLCKCI_00329 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEKLCKCI_00330 8.79e-284 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEKLCKCI_00331 1.08e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
NEKLCKCI_00332 5.28e-151 - - - - - - - -
NEKLCKCI_00333 1.35e-156 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEKLCKCI_00334 4.81e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
NEKLCKCI_00335 4.51e-225 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
NEKLCKCI_00336 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEKLCKCI_00337 0.0 - - - S - - - Domain of unknown function (DUF5067)
NEKLCKCI_00339 9.48e-239 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NEKLCKCI_00340 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
NEKLCKCI_00341 4.17e-156 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
NEKLCKCI_00342 7.04e-217 - - - - - - - -
NEKLCKCI_00343 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEKLCKCI_00344 1.61e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEKLCKCI_00345 3.88e-213 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEKLCKCI_00346 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEKLCKCI_00347 8.05e-64 - - - M - - - Lysin motif
NEKLCKCI_00348 2.55e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEKLCKCI_00349 1.31e-289 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEKLCKCI_00350 0.0 - - - L - - - DNA helicase
NEKLCKCI_00351 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEKLCKCI_00352 1.25e-245 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEKLCKCI_00353 2.29e-96 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NEKLCKCI_00354 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
NEKLCKCI_00355 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEKLCKCI_00356 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEKLCKCI_00357 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEKLCKCI_00358 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEKLCKCI_00359 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
NEKLCKCI_00360 1.1e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEKLCKCI_00361 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NEKLCKCI_00362 1.24e-233 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
NEKLCKCI_00365 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEKLCKCI_00366 3.73e-301 - - - G - - - Major Facilitator Superfamily
NEKLCKCI_00367 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NEKLCKCI_00368 5.33e-286 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKLCKCI_00369 1.98e-168 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NEKLCKCI_00370 5.86e-276 - - - GK - - - ROK family
NEKLCKCI_00371 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEKLCKCI_00372 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NEKLCKCI_00373 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEKLCKCI_00374 5.3e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00375 3.74e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00376 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKLCKCI_00377 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
NEKLCKCI_00378 4.35e-125 - - - F - - - NUDIX domain
NEKLCKCI_00380 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
NEKLCKCI_00381 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NEKLCKCI_00382 1.46e-165 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NEKLCKCI_00383 4.4e-310 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
NEKLCKCI_00384 9.68e-293 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
NEKLCKCI_00385 2.97e-243 - - - V - - - Acetyltransferase (GNAT) domain
NEKLCKCI_00386 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEKLCKCI_00387 9.94e-149 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEKLCKCI_00388 3.35e-84 - - - - - - - -
NEKLCKCI_00389 7.58e-248 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NEKLCKCI_00390 1.13e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEKLCKCI_00392 1.74e-118 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEKLCKCI_00393 2.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEKLCKCI_00394 6.87e-172 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
NEKLCKCI_00395 5.96e-09 - - - S - - - Spermine/spermidine synthase domain
NEKLCKCI_00396 3.07e-137 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEKLCKCI_00397 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
NEKLCKCI_00398 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEKLCKCI_00399 3.26e-226 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
NEKLCKCI_00400 1.86e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NEKLCKCI_00401 2.05e-194 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEKLCKCI_00402 6.34e-147 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEKLCKCI_00403 5.17e-192 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
NEKLCKCI_00404 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NEKLCKCI_00405 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NEKLCKCI_00406 3.33e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
NEKLCKCI_00407 8.76e-299 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
NEKLCKCI_00408 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
NEKLCKCI_00409 1.29e-109 - - - - - - - -
NEKLCKCI_00410 3.53e-254 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NEKLCKCI_00411 4.23e-245 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
NEKLCKCI_00412 2.67e-56 - - - - - - - -
NEKLCKCI_00413 3.89e-235 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NEKLCKCI_00414 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00415 5.29e-212 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
NEKLCKCI_00416 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKLCKCI_00417 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEKLCKCI_00418 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEKLCKCI_00419 2.02e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
NEKLCKCI_00420 2.66e-196 - - - S - - - Protein of unknown function (DUF3710)
NEKLCKCI_00421 5.36e-172 - - - S - - - Protein of unknown function (DUF3159)
NEKLCKCI_00422 3.07e-312 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEKLCKCI_00423 7.81e-141 - - - - - - - -
NEKLCKCI_00424 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEKLCKCI_00425 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEKLCKCI_00427 2.59e-212 - - - S - - - Protein conserved in bacteria
NEKLCKCI_00428 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
NEKLCKCI_00429 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEKLCKCI_00430 7.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEKLCKCI_00431 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEKLCKCI_00432 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEKLCKCI_00433 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEKLCKCI_00434 1.56e-177 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
NEKLCKCI_00436 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
NEKLCKCI_00437 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
NEKLCKCI_00438 3.75e-207 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
NEKLCKCI_00439 3.51e-27 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NEKLCKCI_00440 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NEKLCKCI_00441 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
NEKLCKCI_00442 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
NEKLCKCI_00443 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
NEKLCKCI_00444 0.0 - - - S - - - PGAP1-like protein
NEKLCKCI_00446 9.23e-117 - - - - - - - -
NEKLCKCI_00447 4.7e-197 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NEKLCKCI_00448 3.22e-246 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NEKLCKCI_00449 1.78e-121 - - - - - - - -
NEKLCKCI_00450 5.41e-227 - - - S - - - Protein of unknown function DUF58
NEKLCKCI_00451 1.22e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEKLCKCI_00452 7.48e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEKLCKCI_00453 4.24e-105 - - - S - - - LytR cell envelope-related transcriptional attenuator
NEKLCKCI_00454 1.49e-58 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEKLCKCI_00455 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEKLCKCI_00456 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
NEKLCKCI_00457 8.57e-226 - - - - - - - -
NEKLCKCI_00458 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
NEKLCKCI_00459 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEKLCKCI_00460 1.23e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEKLCKCI_00461 1.05e-251 - - - S - - - Protein of unknown function (DUF3027)
NEKLCKCI_00462 4.88e-235 uspA - - T - - - Belongs to the universal stress protein A family
NEKLCKCI_00463 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
NEKLCKCI_00467 5.26e-302 - - - S - - - Domain of Unknown Function (DUF349)
NEKLCKCI_00468 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
NEKLCKCI_00469 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEKLCKCI_00470 5.49e-108 - - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_00471 5.55e-121 - - - S - - - Aminoacyl-tRNA editing domain
NEKLCKCI_00472 2.08e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
NEKLCKCI_00473 5.91e-196 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NEKLCKCI_00474 2.97e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00475 6.57e-253 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_00476 8.33e-254 - - - S - - - Polyphosphate kinase 2 (PPK2)
NEKLCKCI_00477 0.0 - - - L - - - DEAD DEAH box helicase
NEKLCKCI_00478 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
NEKLCKCI_00480 0.0 - - - EGP - - - Major Facilitator Superfamily
NEKLCKCI_00481 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00482 3.98e-135 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEKLCKCI_00483 5.64e-179 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKLCKCI_00484 3.37e-270 - - - E - - - Aminotransferase class I and II
NEKLCKCI_00485 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00486 6.99e-92 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NEKLCKCI_00487 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEKLCKCI_00488 0.0 - - - S - - - Tetratricopeptide repeat
NEKLCKCI_00489 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEKLCKCI_00490 1.94e-267 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEKLCKCI_00491 1.73e-204 - - - S - - - Protein conserved in bacteria
NEKLCKCI_00492 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEKLCKCI_00493 5.21e-183 - - - S - - - Domain of unknown function (DUF4191)
NEKLCKCI_00494 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NEKLCKCI_00495 1.7e-133 - - - S - - - Protein of unknown function (DUF3043)
NEKLCKCI_00496 0.0 argE - - E - - - Peptidase dimerisation domain
NEKLCKCI_00497 5.31e-245 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
NEKLCKCI_00498 3.58e-196 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00499 4.13e-255 - - - - - - - -
NEKLCKCI_00500 5.1e-300 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
NEKLCKCI_00501 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
NEKLCKCI_00502 1.18e-272 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEKLCKCI_00503 0.0 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEKLCKCI_00504 1.1e-279 - - - I ko:K13663 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
NEKLCKCI_00507 2.58e-165 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEKLCKCI_00508 3.47e-252 - - - GM - - - GDP-mannose 4,6 dehydratase
NEKLCKCI_00509 1.2e-194 - - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NEKLCKCI_00510 1.97e-186 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEKLCKCI_00511 9.1e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NEKLCKCI_00512 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEKLCKCI_00513 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEKLCKCI_00514 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
NEKLCKCI_00515 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
NEKLCKCI_00516 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEKLCKCI_00517 3.44e-130 - - - D - - - Septum formation initiator
NEKLCKCI_00518 8.88e-138 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
NEKLCKCI_00519 1.69e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NEKLCKCI_00521 4.4e-126 - - - - - - - -
NEKLCKCI_00522 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
NEKLCKCI_00523 8.53e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
NEKLCKCI_00524 1.38e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEKLCKCI_00526 5.14e-137 - - - - - - - -
NEKLCKCI_00527 1.95e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NEKLCKCI_00528 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEKLCKCI_00529 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEKLCKCI_00530 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
NEKLCKCI_00531 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
NEKLCKCI_00532 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEKLCKCI_00533 0.0 - - - S - - - Glycosyl transferase, family 2
NEKLCKCI_00534 0.0 - - - - - - - -
NEKLCKCI_00535 1.05e-85 - - - S - - - Zincin-like metallopeptidase
NEKLCKCI_00536 2.72e-199 - - - T - - - Eukaryotic phosphomannomutase
NEKLCKCI_00537 7.4e-165 pyrE_1 - - S - - - Phosphoribosyl transferase domain
NEKLCKCI_00538 3.2e-93 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
NEKLCKCI_00539 1.69e-258 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEKLCKCI_00540 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
NEKLCKCI_00541 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEKLCKCI_00542 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
NEKLCKCI_00543 3.12e-109 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEKLCKCI_00544 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
NEKLCKCI_00545 6.96e-211 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00546 1.55e-232 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NEKLCKCI_00547 7e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEKLCKCI_00548 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NEKLCKCI_00549 4.53e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEKLCKCI_00550 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEKLCKCI_00551 4.13e-230 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
NEKLCKCI_00552 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
NEKLCKCI_00553 4.9e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NEKLCKCI_00555 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
NEKLCKCI_00556 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEKLCKCI_00557 3.12e-220 - - - L - - - NIF3 (NGG1p interacting factor 3)
NEKLCKCI_00558 1.56e-153 - - - L - - - NUDIX domain
NEKLCKCI_00559 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NEKLCKCI_00560 5.67e-278 - - - - - - - -
NEKLCKCI_00562 2.38e-20 - - - - - - - -
NEKLCKCI_00563 1.3e-58 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEKLCKCI_00564 5.61e-23 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEKLCKCI_00565 4.21e-21 - - - U - - - Major Facilitator Superfamily
NEKLCKCI_00566 3.5e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKLCKCI_00567 1.82e-90 - - - K - - - helix_turn_helix, mercury resistance
NEKLCKCI_00568 7.87e-209 - - - S - - - Aldo/keto reductase family
NEKLCKCI_00569 9.75e-131 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NEKLCKCI_00570 1.37e-164 - - - - - - - -
NEKLCKCI_00572 9.85e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
NEKLCKCI_00573 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEKLCKCI_00574 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEKLCKCI_00575 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
NEKLCKCI_00576 2.71e-101 - - - - - - - -
NEKLCKCI_00578 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEKLCKCI_00579 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NEKLCKCI_00580 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
NEKLCKCI_00581 2e-149 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
NEKLCKCI_00582 6.55e-155 - - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_00583 8.41e-298 - - - T - - - Histidine kinase
NEKLCKCI_00584 2.51e-56 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
NEKLCKCI_00585 2.52e-237 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_00586 2.77e-290 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEKLCKCI_00587 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEKLCKCI_00588 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEKLCKCI_00589 1.76e-260 - - - L - - - Transposase and inactivated derivatives IS30 family
NEKLCKCI_00591 4.75e-102 - - - - - - - -
NEKLCKCI_00592 7.23e-85 - - - D - - - MobA/MobL family
NEKLCKCI_00593 9e-64 - - - L ko:K07483 - ko00000 Transposase
NEKLCKCI_00594 1.31e-124 tnp3521a2 - - L - - - Integrase core domain
NEKLCKCI_00595 8.68e-229 - - - L - - - Phage integrase family
NEKLCKCI_00596 2.45e-61 - - - - - - - -
NEKLCKCI_00597 3.27e-183 nfrA - - C - - - Nitroreductase family
NEKLCKCI_00598 9.49e-90 - - - S - - - Protein of unknown function (DUF4235)
NEKLCKCI_00599 1.02e-171 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NEKLCKCI_00601 9.58e-244 - - - K - - - Psort location Cytoplasmic, score
NEKLCKCI_00602 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
NEKLCKCI_00603 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NEKLCKCI_00604 3.29e-80 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEKLCKCI_00605 2.72e-236 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
NEKLCKCI_00606 9.12e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
NEKLCKCI_00607 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NEKLCKCI_00608 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
NEKLCKCI_00609 1.67e-177 - - - S - - - HAD hydrolase, family IA, variant 3
NEKLCKCI_00611 7.42e-162 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NEKLCKCI_00612 7.3e-219 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEKLCKCI_00613 1.6e-83 - - - - - - - -
NEKLCKCI_00614 9.35e-171 - - - - - - - -
NEKLCKCI_00615 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEKLCKCI_00616 1.72e-110 - - - K - - - Transcriptional regulator
NEKLCKCI_00618 1.33e-45 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
NEKLCKCI_00619 3.03e-248 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
NEKLCKCI_00620 6.41e-236 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
NEKLCKCI_00621 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEKLCKCI_00623 3.34e-211 - - - S - - - Glutamine amidotransferase domain
NEKLCKCI_00624 3.28e-176 - - - T ko:K06950 - ko00000 HD domain
NEKLCKCI_00625 3.99e-270 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_00626 0.0 - - - V - - - ABC transporter permease
NEKLCKCI_00627 0.0 - - - H - - - Protein of unknown function (DUF4012)
NEKLCKCI_00628 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_00629 1.93e-211 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEKLCKCI_00630 2.41e-37 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
NEKLCKCI_00631 0.00015 - - - - - - - -
NEKLCKCI_00632 0.0 - - - - - - - -
NEKLCKCI_00633 3.04e-266 - - - S - - - Glycosyltransferase, group 2 family protein
NEKLCKCI_00634 3.15e-75 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NEKLCKCI_00635 1.97e-56 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NEKLCKCI_00636 3.04e-129 - - - - - - - -
NEKLCKCI_00637 5.71e-257 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
NEKLCKCI_00638 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEKLCKCI_00640 3.85e-196 - - - D - - - bacterial-type flagellum organization
NEKLCKCI_00641 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
NEKLCKCI_00642 6.16e-156 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
NEKLCKCI_00643 2.66e-112 - - - NU - - - Type II secretion system (T2SS), protein F
NEKLCKCI_00644 1.13e-54 - - - S - - - Protein of unknown function (DUF4244)
NEKLCKCI_00645 1.28e-73 - - - U - - - TadE-like protein
NEKLCKCI_00646 3.62e-73 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
NEKLCKCI_00647 3.79e-273 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
NEKLCKCI_00648 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
NEKLCKCI_00649 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEKLCKCI_00650 2.68e-175 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NEKLCKCI_00651 2.36e-125 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NEKLCKCI_00653 5.34e-269 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEKLCKCI_00654 1.77e-148 - - - - - - - -
NEKLCKCI_00655 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
NEKLCKCI_00656 0.0 - - - S - - - Calcineurin-like phosphoesterase
NEKLCKCI_00657 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEKLCKCI_00658 0.0 pbp5 - - M - - - Transglycosylase
NEKLCKCI_00659 1.27e-295 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEKLCKCI_00660 6.24e-180 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NEKLCKCI_00661 0.0 - - - M - - - PA domain
NEKLCKCI_00662 2.65e-250 - - - I - - - PAP2 superfamily
NEKLCKCI_00663 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEKLCKCI_00664 2.08e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEKLCKCI_00665 4.97e-271 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEKLCKCI_00666 8.04e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_00667 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
NEKLCKCI_00668 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEKLCKCI_00669 4.92e-53 - - - S - - - Fic/DOC family
NEKLCKCI_00670 2.11e-250 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEKLCKCI_00671 3.52e-32 - - - G - - - MFS/sugar transport protein
NEKLCKCI_00672 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
NEKLCKCI_00673 4.8e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
NEKLCKCI_00674 1.76e-295 - - - S - - - Predicted membrane protein (DUF2318)
NEKLCKCI_00675 1.87e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEKLCKCI_00676 3.5e-276 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEKLCKCI_00677 7.76e-191 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00678 8.08e-103 - - - S - - - FMN_bind
NEKLCKCI_00679 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
NEKLCKCI_00680 1.32e-85 - - - S - - - haloacid dehalogenase-like hydrolase
NEKLCKCI_00681 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEKLCKCI_00682 5.95e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEKLCKCI_00683 1.29e-66 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEKLCKCI_00684 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
NEKLCKCI_00685 1.89e-47 - - - Q - - - phosphatase activity
NEKLCKCI_00686 2.24e-103 - - - - - - - -
NEKLCKCI_00687 1.13e-307 - - - S - - - Putative ABC-transporter type IV
NEKLCKCI_00688 3.89e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKLCKCI_00690 4.05e-221 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEKLCKCI_00691 1.31e-269 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
NEKLCKCI_00692 4.97e-235 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
NEKLCKCI_00693 0.0 - - - M - - - LPXTG cell wall anchor motif
NEKLCKCI_00694 7.68e-105 - - - K - - - Winged helix DNA-binding domain
NEKLCKCI_00695 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00696 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NEKLCKCI_00697 8.19e-107 - - - - - - - -
NEKLCKCI_00698 4.02e-89 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NEKLCKCI_00699 5.86e-25 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NEKLCKCI_00701 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NEKLCKCI_00702 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
NEKLCKCI_00703 1.96e-254 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
NEKLCKCI_00704 1.36e-171 icaR - - K - - - Bacterial regulatory proteins, tetR family
NEKLCKCI_00706 1.83e-278 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEKLCKCI_00707 8.54e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
NEKLCKCI_00708 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
NEKLCKCI_00709 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
NEKLCKCI_00710 0.0 dinF - - V - - - MatE
NEKLCKCI_00711 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEKLCKCI_00712 0.0 murE - - M - - - Domain of unknown function (DUF1727)
NEKLCKCI_00713 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
NEKLCKCI_00714 3.15e-44 - - - S - - - granule-associated protein
NEKLCKCI_00715 0.0 - - - S ko:K03688 - ko00000 ABC1 family
NEKLCKCI_00716 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NEKLCKCI_00717 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
NEKLCKCI_00718 2.51e-298 rmuC - - S ko:K09760 - ko00000 RmuC family
NEKLCKCI_00719 2.47e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEKLCKCI_00720 1.94e-213 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
NEKLCKCI_00721 4.24e-78 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_00722 5.3e-79 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_00723 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEKLCKCI_00724 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEKLCKCI_00725 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEKLCKCI_00726 1.96e-251 - - - J - - - Acetyltransferase (GNAT) domain
NEKLCKCI_00727 6.51e-69 - - - S - - - Protein of unknown function (DUF2469)
NEKLCKCI_00729 0.0 - - - H - - - Flavin containing amine oxidoreductase
NEKLCKCI_00730 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEKLCKCI_00731 8.68e-299 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
NEKLCKCI_00732 7.67e-118 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
NEKLCKCI_00733 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
NEKLCKCI_00734 0.0 - - - S - - - domain protein
NEKLCKCI_00735 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEKLCKCI_00736 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEKLCKCI_00737 8.16e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEKLCKCI_00738 7.59e-173 glnR - - KT - - - Transcriptional regulatory protein, C terminal
NEKLCKCI_00739 5.6e-170 - - - - - - - -
NEKLCKCI_00740 2.85e-134 mntP - - P - - - Probably functions as a manganese efflux pump
NEKLCKCI_00742 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NEKLCKCI_00743 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NEKLCKCI_00744 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
NEKLCKCI_00745 2.63e-48 - - - - - - - -
NEKLCKCI_00747 2.41e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEKLCKCI_00748 4.13e-187 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEKLCKCI_00749 2.39e-41 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEKLCKCI_00750 7.5e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEKLCKCI_00751 5.66e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEKLCKCI_00752 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEKLCKCI_00753 2.73e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEKLCKCI_00754 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEKLCKCI_00755 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NEKLCKCI_00756 3.16e-168 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NEKLCKCI_00757 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
NEKLCKCI_00758 0.0 - - - - - - - -
NEKLCKCI_00759 4.75e-196 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
NEKLCKCI_00760 2.14e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NEKLCKCI_00761 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NEKLCKCI_00762 0.0 pccB - - I - - - Carboxyl transferase domain
NEKLCKCI_00763 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
NEKLCKCI_00764 5.82e-130 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEKLCKCI_00765 4.39e-209 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
NEKLCKCI_00767 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NEKLCKCI_00768 3.14e-155 - - - - - - - -
NEKLCKCI_00769 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEKLCKCI_00770 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEKLCKCI_00771 1.39e-150 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
NEKLCKCI_00772 2.19e-56 - - - K - - - purine nucleotide biosynthetic process
NEKLCKCI_00773 1.52e-122 lemA - - S ko:K03744 - ko00000 LemA family
NEKLCKCI_00774 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NEKLCKCI_00775 2.45e-91 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEKLCKCI_00776 1.03e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEKLCKCI_00777 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEKLCKCI_00778 3.47e-128 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NEKLCKCI_00779 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NEKLCKCI_00780 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
NEKLCKCI_00781 1.25e-215 - - - L - - - Transposase and inactivated derivatives IS30 family
NEKLCKCI_00782 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
NEKLCKCI_00783 2.25e-240 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
NEKLCKCI_00784 5.01e-183 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEKLCKCI_00785 2.61e-163 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEKLCKCI_00786 1.08e-123 - - - D - - - nuclear chromosome segregation
NEKLCKCI_00787 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEKLCKCI_00788 2.9e-231 - - - L - - - Excalibur calcium-binding domain
NEKLCKCI_00789 1.14e-276 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEKLCKCI_00790 1.1e-312 - - - EGP - - - Major Facilitator Superfamily
NEKLCKCI_00791 2.63e-142 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEKLCKCI_00792 3.6e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEKLCKCI_00793 7.68e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEKLCKCI_00794 2.48e-309 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NEKLCKCI_00795 3.28e-166 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NEKLCKCI_00796 1.71e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
NEKLCKCI_00797 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEKLCKCI_00798 1.89e-233 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NEKLCKCI_00799 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEKLCKCI_00800 7.39e-219 - - - S - - - Protein conserved in bacteria
NEKLCKCI_00802 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
NEKLCKCI_00804 0.0 - - - G - - - BNR repeat-like domain
NEKLCKCI_00805 5.46e-230 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
NEKLCKCI_00806 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEKLCKCI_00807 5.13e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEKLCKCI_00809 0.0 - - - T - - - Forkhead associated domain
NEKLCKCI_00810 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
NEKLCKCI_00811 2.87e-56 - - - - - - - -
NEKLCKCI_00812 7.04e-140 - - - NO - - - SAF
NEKLCKCI_00813 1.88e-51 - - - S - - - Putative regulatory protein
NEKLCKCI_00814 3.43e-155 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
NEKLCKCI_00815 1.2e-191 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEKLCKCI_00816 2.25e-266 - - - - - - - -
NEKLCKCI_00817 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEKLCKCI_00818 9.61e-168 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEKLCKCI_00819 6.42e-57 yeaC - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEKLCKCI_00824 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
NEKLCKCI_00825 4.5e-279 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEKLCKCI_00826 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
NEKLCKCI_00827 2.84e-285 dapC - - E - - - Aminotransferase class I and II
NEKLCKCI_00828 1.89e-306 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEKLCKCI_00830 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
NEKLCKCI_00831 4e-147 yigZ - - S - - - Uncharacterized protein family UPF0029
NEKLCKCI_00832 1.25e-156 - - - - - - - -
NEKLCKCI_00833 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NEKLCKCI_00834 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEKLCKCI_00835 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEKLCKCI_00836 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NEKLCKCI_00837 2.49e-297 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NEKLCKCI_00838 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEKLCKCI_00839 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NEKLCKCI_00840 3.03e-40 - - - S - - - YwiC-like protein
NEKLCKCI_00841 6.49e-05 - - - S - - - YwiC-like protein
NEKLCKCI_00842 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NEKLCKCI_00843 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEKLCKCI_00844 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NEKLCKCI_00845 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEKLCKCI_00846 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEKLCKCI_00847 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEKLCKCI_00848 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEKLCKCI_00849 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEKLCKCI_00850 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEKLCKCI_00851 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NEKLCKCI_00852 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEKLCKCI_00853 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEKLCKCI_00854 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEKLCKCI_00855 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEKLCKCI_00856 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEKLCKCI_00857 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEKLCKCI_00858 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEKLCKCI_00859 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEKLCKCI_00860 2.04e-149 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEKLCKCI_00861 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
NEKLCKCI_00862 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NEKLCKCI_00863 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEKLCKCI_00864 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEKLCKCI_00865 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEKLCKCI_00866 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NEKLCKCI_00867 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEKLCKCI_00868 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEKLCKCI_00869 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEKLCKCI_00870 2.18e-94 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEKLCKCI_00871 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
NEKLCKCI_00872 4.08e-221 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEKLCKCI_00873 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
NEKLCKCI_00874 9.14e-198 - - - E - - - Transglutaminase/protease-like homologues
NEKLCKCI_00876 1.05e-167 tnp3503b - - L - - - Transposase and inactivated derivatives
NEKLCKCI_00877 1.33e-226 - - - - - - - -
NEKLCKCI_00878 1.16e-241 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEKLCKCI_00879 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEKLCKCI_00880 8.76e-124 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEKLCKCI_00881 9.52e-301 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEKLCKCI_00882 1.78e-304 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
NEKLCKCI_00883 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEKLCKCI_00884 6.9e-142 - - - - - - - -
NEKLCKCI_00885 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
NEKLCKCI_00886 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEKLCKCI_00887 4.34e-261 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEKLCKCI_00888 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NEKLCKCI_00889 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NEKLCKCI_00890 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NEKLCKCI_00892 1.72e-90 - - - M - - - Spy0128-like isopeptide containing domain
NEKLCKCI_00893 8.64e-05 - - - O ko:K18546 - ko00000,ko01000,ko01002 Peptidase s1 and s6 chymotrypsin hap
NEKLCKCI_00894 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
NEKLCKCI_00895 5.06e-198 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEKLCKCI_00896 3.25e-273 - - - I - - - Diacylglycerol kinase catalytic domain
NEKLCKCI_00897 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NEKLCKCI_00898 1.26e-304 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEKLCKCI_00900 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
NEKLCKCI_00902 4.52e-123 - - - - - - - -
NEKLCKCI_00903 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEKLCKCI_00904 7.54e-240 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
NEKLCKCI_00905 5.83e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NEKLCKCI_00907 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEKLCKCI_00908 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_00909 0.0 tcsS3 - - KT - - - PspC domain
NEKLCKCI_00910 0.0 pspC - - KT - - - PspC domain
NEKLCKCI_00911 1.6e-203 - - - - - - - -
NEKLCKCI_00912 9.55e-146 - - - S - - - Protein of unknown function (DUF4125)
NEKLCKCI_00913 0.0 - - - S - - - Domain of unknown function (DUF4037)
NEKLCKCI_00914 7.45e-278 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
NEKLCKCI_00916 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEKLCKCI_00917 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NEKLCKCI_00918 3.69e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEKLCKCI_00920 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEKLCKCI_00921 9.24e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEKLCKCI_00922 4.6e-53 - - - - - - - -
NEKLCKCI_00923 1.28e-275 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEKLCKCI_00924 3.37e-228 - - - S - - - CHAP domain
NEKLCKCI_00925 2.08e-147 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NEKLCKCI_00926 1.31e-244 - - - T - - - Universal stress protein family
NEKLCKCI_00927 5.09e-93 - - - O - - - OsmC-like protein
NEKLCKCI_00928 4.99e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEKLCKCI_00929 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
NEKLCKCI_00930 2.34e-124 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
NEKLCKCI_00931 1.27e-249 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEKLCKCI_00932 1.86e-31 - - - E - - - Branched-chain amino acid transport protein (AzlD)
NEKLCKCI_00933 5.06e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_00934 7.89e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NEKLCKCI_00935 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEKLCKCI_00936 2e-09 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NEKLCKCI_00937 1.38e-235 - - - - - - - -
NEKLCKCI_00938 6.72e-140 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_00939 1.02e-152 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
NEKLCKCI_00940 1.03e-141 - - - - - - - -
NEKLCKCI_00941 1.83e-244 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NEKLCKCI_00942 9.41e-283 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEKLCKCI_00943 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEKLCKCI_00944 8.97e-119 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEKLCKCI_00946 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEKLCKCI_00947 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
NEKLCKCI_00948 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEKLCKCI_00949 3.55e-313 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
NEKLCKCI_00950 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEKLCKCI_00951 8.77e-203 - - - K - - - Helix-turn-helix domain, rpiR family
NEKLCKCI_00952 8.56e-289 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEKLCKCI_00953 3.01e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
NEKLCKCI_00955 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEKLCKCI_00956 8.31e-228 yogA - - C - - - Zinc-binding dehydrogenase
NEKLCKCI_00957 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEKLCKCI_00958 8.53e-290 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEKLCKCI_00959 1.27e-94 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NEKLCKCI_00960 2.28e-62 - - - - - - - -
NEKLCKCI_00961 3.19e-198 - - - S - - - TIGRFAM TIGR03943 family protein
NEKLCKCI_00962 2.5e-258 - - - S ko:K07089 - ko00000 Predicted permease
NEKLCKCI_00963 1.07e-32 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
NEKLCKCI_00964 3.58e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
NEKLCKCI_00965 7.57e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEKLCKCI_00966 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEKLCKCI_00967 2.64e-63 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NEKLCKCI_00968 4.46e-179 - - - S - - - cobalamin synthesis protein
NEKLCKCI_00969 6.69e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NEKLCKCI_00970 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
NEKLCKCI_00971 0.0 - - - S - - - Putative esterase
NEKLCKCI_00972 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NEKLCKCI_00973 5.35e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NEKLCKCI_00974 2.1e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NEKLCKCI_00975 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEKLCKCI_00976 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
NEKLCKCI_00977 9.82e-45 - - - - - - - -
NEKLCKCI_00978 1.64e-90 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEKLCKCI_00979 4.51e-44 - - - K - - - DNA-binding transcription factor activity
NEKLCKCI_00980 3.66e-187 nnrE - - L - - - Uracil DNA glycosylase superfamily
NEKLCKCI_00981 2.2e-140 - - - S - - - Protein of unknown function (DUF4230)
NEKLCKCI_00982 6.26e-146 - - - - - - - -
NEKLCKCI_00983 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
NEKLCKCI_00984 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NEKLCKCI_00985 4.7e-299 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEKLCKCI_00986 0.0 - - - M - - - Parallel beta-helix repeats
NEKLCKCI_00987 1.04e-289 - - - M - - - Glycosyl transferase 4-like domain
NEKLCKCI_00988 1.33e-255 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
NEKLCKCI_00990 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEKLCKCI_00991 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEKLCKCI_00992 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEKLCKCI_00993 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEKLCKCI_00994 0.0 - - - S - - - Esterase-like activity of phytase
NEKLCKCI_00995 7.97e-250 - - - EGP - - - Transmembrane secretion effector
NEKLCKCI_00997 3.8e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEKLCKCI_00998 1.61e-147 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEKLCKCI_00999 1.4e-303 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NEKLCKCI_01000 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NEKLCKCI_01001 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEKLCKCI_01002 0.0 - - - S - - - Protein of unknown function DUF262
NEKLCKCI_01003 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_01004 0.0 - - - T - - - Histidine kinase
NEKLCKCI_01005 2.17e-151 - - - S - - - Domain of unknown function (DUF5067)
NEKLCKCI_01006 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEKLCKCI_01007 1.01e-214 - - - EG - - - EamA-like transporter family
NEKLCKCI_01008 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
NEKLCKCI_01009 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEKLCKCI_01010 2.54e-235 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEKLCKCI_01011 3.51e-174 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NEKLCKCI_01012 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
NEKLCKCI_01013 6.37e-160 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEKLCKCI_01014 1.14e-124 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NEKLCKCI_01015 1.03e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKLCKCI_01016 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
NEKLCKCI_01017 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEKLCKCI_01018 1.2e-113 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NEKLCKCI_01021 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEKLCKCI_01022 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEKLCKCI_01023 4.2e-242 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEKLCKCI_01024 4.56e-142 - - - - - - - -
NEKLCKCI_01025 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NEKLCKCI_01026 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
NEKLCKCI_01027 7.75e-258 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEKLCKCI_01028 3.42e-158 - - - - - - - -
NEKLCKCI_01029 1.99e-250 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEKLCKCI_01030 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NEKLCKCI_01031 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NEKLCKCI_01032 1.12e-49 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NEKLCKCI_01033 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
NEKLCKCI_01034 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NEKLCKCI_01035 3.16e-298 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
NEKLCKCI_01036 1.1e-234 - - - S - - - Protein of unknown function (DUF3071)
NEKLCKCI_01037 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
NEKLCKCI_01038 1.75e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NEKLCKCI_01039 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEKLCKCI_01041 3.6e-266 - - - E - - - Belongs to the peptidase S1B family
NEKLCKCI_01042 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
NEKLCKCI_01043 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NEKLCKCI_01044 3.89e-118 - - - K - - - helix-turn-helix
NEKLCKCI_01045 4.33e-161 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEKLCKCI_01046 1.74e-253 - - - K - - - Replication initiation factor
NEKLCKCI_01047 6.67e-43 - - - L - - - Excisionase from transposon Tn916
NEKLCKCI_01048 4.9e-93 - - - L - - - COG COG4974 Site-specific recombinase XerD
NEKLCKCI_01049 6.34e-178 - - - L - - - COG COG4974 Site-specific recombinase XerD
NEKLCKCI_01050 1.98e-133 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEKLCKCI_01051 5.56e-212 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKLCKCI_01053 6.96e-286 - - - S - - - Peptidase dimerisation domain
NEKLCKCI_01054 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEKLCKCI_01055 7.81e-52 - - - - - - - -
NEKLCKCI_01056 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NEKLCKCI_01057 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEKLCKCI_01058 2.98e-144 - - - S - - - Protein of unknown function (DUF3000)
NEKLCKCI_01059 1.94e-316 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
NEKLCKCI_01060 9.36e-310 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEKLCKCI_01061 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
NEKLCKCI_01062 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEKLCKCI_01063 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEKLCKCI_01064 7.12e-311 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEKLCKCI_01067 1.82e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
NEKLCKCI_01068 8.28e-291 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NEKLCKCI_01069 4.26e-222 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NEKLCKCI_01070 6.09e-152 safC - - S - - - O-methyltransferase
NEKLCKCI_01071 3.57e-235 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NEKLCKCI_01072 2.23e-93 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
NEKLCKCI_01073 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
NEKLCKCI_01074 1.72e-42 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
NEKLCKCI_01075 1.71e-307 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
NEKLCKCI_01076 1.52e-75 - - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NEKLCKCI_01077 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
NEKLCKCI_01078 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NEKLCKCI_01079 9.86e-202 - - - S - - - Putative ABC-transporter type IV
NEKLCKCI_01080 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
NEKLCKCI_01081 9.42e-209 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_01082 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEKLCKCI_01083 0.0 - - - I - - - PAP2 superfamily
NEKLCKCI_01084 2.92e-171 - - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_01085 0.0 - - - T - - - Histidine kinase
NEKLCKCI_01086 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
NEKLCKCI_01087 4.99e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEKLCKCI_01088 3.08e-215 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
NEKLCKCI_01089 9.38e-190 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NEKLCKCI_01090 2.69e-239 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NEKLCKCI_01091 3.16e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NEKLCKCI_01092 3.17e-260 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEKLCKCI_01093 4.84e-123 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_01094 1.04e-291 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NEKLCKCI_01095 2.92e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEKLCKCI_01096 9.38e-312 - - - K - - - Fic/DOC family
NEKLCKCI_01097 1.92e-162 - - - E - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_01098 5.59e-78 yccF - - S - - - Inner membrane component domain
NEKLCKCI_01099 6.35e-201 - - - J - - - Methyltransferase domain
NEKLCKCI_01100 6.29e-103 - - - S - - - Cupin 2, conserved barrel domain protein
NEKLCKCI_01101 0.0 - - - KLT - - - Protein tyrosine kinase
NEKLCKCI_01102 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
NEKLCKCI_01104 1.1e-30 - - - - - - - -
NEKLCKCI_01105 7.74e-264 - - - S - - - Short C-terminal domain
NEKLCKCI_01106 4.48e-112 - - - S - - - Helix-turn-helix
NEKLCKCI_01107 7.03e-86 - - - S - - - Zincin-like metallopeptidase
NEKLCKCI_01108 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NEKLCKCI_01109 6.57e-66 - - - - - - - -
NEKLCKCI_01110 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEKLCKCI_01111 5.26e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NEKLCKCI_01112 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
NEKLCKCI_01114 0.0 - - - M - - - Glycosyltransferase like family 2
NEKLCKCI_01115 3.18e-153 - - - E - - - haloacid dehalogenase-like hydrolase
NEKLCKCI_01116 2.58e-186 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NEKLCKCI_01117 3.71e-239 - - - S - - - Conserved hypothetical protein 698
NEKLCKCI_01118 4.12e-79 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NEKLCKCI_01119 6.99e-204 - - - G - - - Phosphoglycerate mutase family
NEKLCKCI_01120 3.21e-303 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
NEKLCKCI_01121 6.43e-110 - - - K - - - AraC-like ligand binding domain
NEKLCKCI_01123 1.03e-70 - - - IQ - - - oxidoreductase activity
NEKLCKCI_01124 2.65e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NEKLCKCI_01125 1.43e-174 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01126 1.3e-204 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEKLCKCI_01127 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEKLCKCI_01128 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
NEKLCKCI_01129 6.1e-134 - - - - - - - -
NEKLCKCI_01130 7.48e-260 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEKLCKCI_01131 2.47e-273 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEKLCKCI_01132 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NEKLCKCI_01133 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
NEKLCKCI_01134 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEKLCKCI_01135 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEKLCKCI_01136 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEKLCKCI_01137 2.21e-47 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
NEKLCKCI_01138 1.74e-75 - - - S - - - pathogenesis
NEKLCKCI_01139 6.9e-85 - - - - - - - -
NEKLCKCI_01141 1.71e-116 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
NEKLCKCI_01143 1.13e-108 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEKLCKCI_01144 1.65e-72 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKLCKCI_01145 1.62e-131 - - - S - - - Protein of unknown function (DUF4127)
NEKLCKCI_01146 2.14e-119 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_01147 2.78e-177 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NEKLCKCI_01148 4.94e-39 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NEKLCKCI_01149 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NEKLCKCI_01150 5.91e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEKLCKCI_01151 5.2e-173 - - - L - - - Protein of unknown function (DUF1524)
NEKLCKCI_01152 4.25e-217 - - - S - - - Oxidoreductase, aldo keto reductase family protein
NEKLCKCI_01154 4.4e-256 - - - K - - - helix_turn _helix lactose operon repressor
NEKLCKCI_01155 2.44e-130 - - - G - - - Glycosyl hydrolases family 43
NEKLCKCI_01156 1.14e-218 - - - G - - - Glycosyl hydrolases family 43
NEKLCKCI_01159 1.35e-142 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NEKLCKCI_01160 8.26e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NEKLCKCI_01161 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NEKLCKCI_01162 7.62e-258 - - - K - - - helix_turn _helix lactose operon repressor
NEKLCKCI_01163 1.9e-169 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEKLCKCI_01164 4.9e-200 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEKLCKCI_01165 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEKLCKCI_01166 9.8e-166 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
NEKLCKCI_01167 6.29e-220 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
NEKLCKCI_01168 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NEKLCKCI_01169 1.46e-283 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEKLCKCI_01170 4.07e-220 - - - K - - - Putative sugar-binding domain
NEKLCKCI_01172 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_01173 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01174 1e-28 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
NEKLCKCI_01175 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
NEKLCKCI_01176 4.87e-155 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
NEKLCKCI_01178 6.19e-263 - - - - - - - -
NEKLCKCI_01181 2.09e-272 - - - - - - - -
NEKLCKCI_01182 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEKLCKCI_01185 1.61e-227 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
NEKLCKCI_01186 2.8e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEKLCKCI_01187 1.92e-172 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEKLCKCI_01188 2.46e-315 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEKLCKCI_01191 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NEKLCKCI_01192 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
NEKLCKCI_01193 1.56e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEKLCKCI_01194 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NEKLCKCI_01195 2.17e-147 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NEKLCKCI_01196 3.01e-184 - - - - - - - -
NEKLCKCI_01197 3.67e-105 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEKLCKCI_01198 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
NEKLCKCI_01199 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
NEKLCKCI_01200 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
NEKLCKCI_01201 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKLCKCI_01202 2.09e-212 - - - P - - - Cation efflux family
NEKLCKCI_01203 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEKLCKCI_01204 6.97e-285 - - - S - - - Endonuclease/Exonuclease/phosphatase family
NEKLCKCI_01205 1.36e-131 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NEKLCKCI_01206 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NEKLCKCI_01207 2.4e-80 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEKLCKCI_01208 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NEKLCKCI_01209 9.23e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEKLCKCI_01210 1.37e-223 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEKLCKCI_01211 1.25e-106 - - - O - - - Hsp20/alpha crystallin family
NEKLCKCI_01212 2.16e-136 - - - S ko:K07078 - ko00000 Nitroreductase family
NEKLCKCI_01213 4.41e-155 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
NEKLCKCI_01214 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
NEKLCKCI_01215 0.0 - - - - - - - -
NEKLCKCI_01218 3.02e-279 steT - - E ko:K03294 - ko00000 amino acid
NEKLCKCI_01219 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
NEKLCKCI_01220 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NEKLCKCI_01221 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
NEKLCKCI_01223 2.47e-308 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NEKLCKCI_01224 1.36e-104 - - - K - - - helix_turn_helix, mercury resistance
NEKLCKCI_01226 1.77e-72 - - - L - - - RelB antitoxin
NEKLCKCI_01227 4.24e-92 - - - - - - - -
NEKLCKCI_01228 6.85e-151 - 2.1.1.72 - L ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
NEKLCKCI_01229 4.26e-29 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NEKLCKCI_01230 4.71e-241 - - - L - - - Transposase
NEKLCKCI_01231 7.26e-43 - - - I - - - carboxylic ester hydrolase activity
NEKLCKCI_01232 1.35e-286 - - - K - - - Helix-turn-helix XRE-family like proteins
NEKLCKCI_01233 6.29e-162 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
NEKLCKCI_01238 0.00013 - - - TV ko:K05792 - ko00000 HNH endonuclease
NEKLCKCI_01239 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NEKLCKCI_01240 2.76e-55 - - - K - - - Transcriptional regulator
NEKLCKCI_01243 7.27e-25 - - - M - - - Belongs to the glycosyl hydrolase 28 family
NEKLCKCI_01244 1.67e-295 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
NEKLCKCI_01245 1.37e-306 - - - S - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_01246 1.51e-153 - - - K - - - Bacterial regulatory proteins, tetR family
NEKLCKCI_01247 1.04e-169 - - - M - - - Mechanosensitive ion channel
NEKLCKCI_01248 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEKLCKCI_01250 8.13e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
NEKLCKCI_01251 2.21e-198 - - - S - - - Domain of unknown function (DUF4854)
NEKLCKCI_01252 6.52e-271 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEKLCKCI_01253 0.0 - - - M - - - LPXTG cell wall anchor motif
NEKLCKCI_01254 0.0 - - - M - - - domain protein
NEKLCKCI_01255 2.45e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
NEKLCKCI_01256 2.58e-190 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEKLCKCI_01257 8.22e-236 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKLCKCI_01258 3.2e-176 - - - M - - - Protein of unknown function (DUF3152)
NEKLCKCI_01259 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKLCKCI_01261 3.4e-90 - - - E - - - Domain of unknown function (DUF5011)
NEKLCKCI_01262 1.22e-53 - - - S - - - Parallel beta-helix repeats
NEKLCKCI_01265 6.71e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEKLCKCI_01266 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEKLCKCI_01267 7.91e-111 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NEKLCKCI_01268 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NEKLCKCI_01269 1.49e-245 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
NEKLCKCI_01270 5.55e-165 - - - - - - - -
NEKLCKCI_01271 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NEKLCKCI_01272 5.34e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEKLCKCI_01273 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
NEKLCKCI_01274 4.46e-255 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEKLCKCI_01275 7.45e-280 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEKLCKCI_01276 1.38e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NEKLCKCI_01277 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NEKLCKCI_01278 5.02e-161 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NEKLCKCI_01279 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEKLCKCI_01281 2.89e-294 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
NEKLCKCI_01282 2.13e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEKLCKCI_01283 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEKLCKCI_01284 7.66e-275 - - - K - - - Psort location Cytoplasmic, score
NEKLCKCI_01285 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
NEKLCKCI_01286 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NEKLCKCI_01287 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
NEKLCKCI_01288 4.04e-304 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NEKLCKCI_01289 5.52e-214 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NEKLCKCI_01290 0.0 - - - V - - - Efflux ABC transporter, permease protein
NEKLCKCI_01291 1.31e-209 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01292 8.09e-76 - - - - - - - -
NEKLCKCI_01293 1.57e-84 - - - - - - - -
NEKLCKCI_01294 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
NEKLCKCI_01295 5.51e-239 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEKLCKCI_01296 6.26e-305 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NEKLCKCI_01297 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEKLCKCI_01298 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEKLCKCI_01299 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEKLCKCI_01300 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NEKLCKCI_01301 5.58e-230 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEKLCKCI_01302 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
NEKLCKCI_01303 1.08e-258 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
NEKLCKCI_01306 2.18e-211 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
NEKLCKCI_01307 1.34e-85 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
NEKLCKCI_01308 2.02e-26 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 carboxylic acid catabolic process
NEKLCKCI_01309 2.41e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
NEKLCKCI_01311 1.65e-153 - - - S - - - CYTH
NEKLCKCI_01312 1.03e-213 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
NEKLCKCI_01313 8.35e-232 - - - - - - - -
NEKLCKCI_01314 9.86e-241 - - - - - - - -
NEKLCKCI_01315 4.41e-223 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
NEKLCKCI_01316 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEKLCKCI_01317 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEKLCKCI_01318 1.61e-186 - - - - - - - -
NEKLCKCI_01319 1.02e-170 - - - K - - - Bacterial regulatory proteins, tetR family
NEKLCKCI_01320 1.05e-292 - - - G - - - Transmembrane secretion effector
NEKLCKCI_01321 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEKLCKCI_01322 3.04e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
NEKLCKCI_01323 5.2e-253 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEKLCKCI_01325 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_01326 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEKLCKCI_01327 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEKLCKCI_01328 1.59e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
NEKLCKCI_01329 9.69e-317 - - - S - - - Calcineurin-like phosphoesterase
NEKLCKCI_01332 3.37e-88 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NEKLCKCI_01333 1.4e-127 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NEKLCKCI_01334 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEKLCKCI_01336 1.65e-159 - - - S - - - HAD hydrolase, family IA, variant 3
NEKLCKCI_01337 1.45e-257 - - - P - - - NMT1/THI5 like
NEKLCKCI_01338 4.1e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
NEKLCKCI_01339 9.25e-198 - - - - - - - -
NEKLCKCI_01340 9.49e-163 - - - G - - - Phosphoglycerate mutase family
NEKLCKCI_01341 0.0 - - - EGP - - - Major Facilitator Superfamily
NEKLCKCI_01342 6.15e-127 - - - S - - - GtrA-like protein
NEKLCKCI_01343 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
NEKLCKCI_01344 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
NEKLCKCI_01345 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NEKLCKCI_01346 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEKLCKCI_01347 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
NEKLCKCI_01348 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NEKLCKCI_01349 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEKLCKCI_01350 8.73e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEKLCKCI_01351 2.3e-58 - - - S - - - Protein of unknown function (DUF1778)
NEKLCKCI_01352 2.2e-244 - - - C - - - Aldo/keto reductase family
NEKLCKCI_01353 2.95e-126 - - - M - - - Belongs to the glycosyl hydrolase 30 family
NEKLCKCI_01354 4.45e-21 - - - - - - - -
NEKLCKCI_01356 3.1e-113 - - - - - - - -
NEKLCKCI_01358 8.66e-121 - - - - - - - -
NEKLCKCI_01359 7.13e-56 - - - O - - - Glutaredoxin
NEKLCKCI_01360 3.2e-191 - - - S ko:K07058 - ko00000 Virulence factor BrkB
NEKLCKCI_01361 5.61e-127 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
NEKLCKCI_01362 3.79e-52 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEKLCKCI_01363 3.17e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEKLCKCI_01364 2.21e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEKLCKCI_01365 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEKLCKCI_01366 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_01367 2.46e-132 - - - K - - - Transcriptional regulator C-terminal region
NEKLCKCI_01368 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
NEKLCKCI_01369 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NEKLCKCI_01370 4.01e-235 - - - S - - - Protein of unknown function (DUF559)
NEKLCKCI_01371 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEKLCKCI_01372 6.15e-261 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEKLCKCI_01373 0.0 - - - EGP - - - Sugar (and other) transporter
NEKLCKCI_01374 0.0 scrT - - G - - - Transporter major facilitator family protein
NEKLCKCI_01375 1.89e-100 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
NEKLCKCI_01376 1.91e-255 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_01377 3.43e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEKLCKCI_01378 3.06e-211 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEKLCKCI_01379 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEKLCKCI_01380 2.17e-253 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NEKLCKCI_01381 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NEKLCKCI_01382 1.42e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEKLCKCI_01384 1.57e-64 - - - E - - - IrrE N-terminal-like domain
NEKLCKCI_01385 1.61e-82 - - - - - - - -
NEKLCKCI_01386 4.37e-80 - - - - - - - -
NEKLCKCI_01388 3.76e-163 - - - S - - - Domain of unknown function (DUF4417)
NEKLCKCI_01389 1.23e-55 - - - S - - - Bacterial mobilisation protein (MobC)
NEKLCKCI_01390 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NEKLCKCI_01392 2.19e-219 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NEKLCKCI_01393 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
NEKLCKCI_01394 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NEKLCKCI_01395 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
NEKLCKCI_01396 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEKLCKCI_01398 4.51e-110 - - - Q - - - Acetyltransferase (GNAT) domain
NEKLCKCI_01399 1.58e-199 - - - I - - - Serine aminopeptidase, S33
NEKLCKCI_01400 1.75e-69 - - - S - - - Putative heavy-metal-binding
NEKLCKCI_01401 1.67e-62 - - - - - - - -
NEKLCKCI_01402 1.15e-116 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEKLCKCI_01403 0.0 - - - KL - - - Domain of unknown function (DUF3427)
NEKLCKCI_01405 4.98e-252 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEKLCKCI_01407 1.11e-145 - - - - - - - -
NEKLCKCI_01408 3.78e-215 - - - EG - - - EamA-like transporter family
NEKLCKCI_01409 1.7e-263 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
NEKLCKCI_01410 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NEKLCKCI_01411 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NEKLCKCI_01412 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
NEKLCKCI_01413 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
NEKLCKCI_01414 1.44e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NEKLCKCI_01415 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
NEKLCKCI_01416 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEKLCKCI_01417 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NEKLCKCI_01418 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NEKLCKCI_01419 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NEKLCKCI_01420 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
NEKLCKCI_01421 5.65e-296 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEKLCKCI_01422 2.05e-183 - - - S - - - Bacterial protein of unknown function (DUF881)
NEKLCKCI_01423 8.05e-100 crgA - - D - - - Involved in cell division
NEKLCKCI_01424 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
NEKLCKCI_01425 2.4e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
NEKLCKCI_01426 7.68e-47 - - - - - - - -
NEKLCKCI_01427 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEKLCKCI_01428 2.26e-95 - - - I - - - Sterol carrier protein
NEKLCKCI_01429 1.49e-51 - - - V ko:K06147 - ko00000,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01430 3.5e-57 - - - L ko:K07485 - ko00000 Transposase
NEKLCKCI_01431 6.48e-14 istB - - L - - - IstB-like ATP binding protein
NEKLCKCI_01432 7.04e-57 - - - L - - - Integrase core domain
NEKLCKCI_01433 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NEKLCKCI_01434 1.9e-17 - - - - - - - -
NEKLCKCI_01435 9.57e-151 - - - K - - - Bacterial regulatory proteins, tetR family
NEKLCKCI_01436 1.78e-28 - - - G - - - Transmembrane secretion effector
NEKLCKCI_01437 2.23e-189 - - - L ko:K07448 - ko00000,ko02048 Restriction endonuclease
NEKLCKCI_01438 1.61e-40 - - - - - - - -
NEKLCKCI_01439 8.54e-126 - - - E - - - Rard protein
NEKLCKCI_01440 3.98e-228 - - - I - - - alpha/beta hydrolase fold
NEKLCKCI_01441 8.16e-265 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NEKLCKCI_01442 2.04e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
NEKLCKCI_01443 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEKLCKCI_01444 1.59e-206 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NEKLCKCI_01446 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NEKLCKCI_01447 2.23e-233 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEKLCKCI_01448 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NEKLCKCI_01449 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEKLCKCI_01450 3.67e-227 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
NEKLCKCI_01451 8.79e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NEKLCKCI_01452 7.1e-230 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEKLCKCI_01453 7.11e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEKLCKCI_01454 2.51e-31 - - - K - - - MerR family regulatory protein
NEKLCKCI_01455 2.1e-246 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NEKLCKCI_01456 1.82e-218 - - - - - - - -
NEKLCKCI_01457 1.4e-22 - - - K - - - Psort location Cytoplasmic, score
NEKLCKCI_01458 9.5e-19 - - - KLT - - - Protein tyrosine kinase
NEKLCKCI_01459 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NEKLCKCI_01460 5.78e-304 - - - V - - - MatE
NEKLCKCI_01461 4.85e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
NEKLCKCI_01462 1.02e-171 - - - L ko:K07457 - ko00000 endonuclease III
NEKLCKCI_01463 2.51e-120 - - - K - - - Transcriptional regulator PadR-like family
NEKLCKCI_01464 9.3e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
NEKLCKCI_01465 8.87e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
NEKLCKCI_01466 4.89e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
NEKLCKCI_01467 1.17e-54 - - - K - - - Helix-turn-helix
NEKLCKCI_01468 1.02e-64 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
NEKLCKCI_01469 6.5e-25 - - - - - - - -
NEKLCKCI_01470 1.66e-131 - - - K - - - Bacterial regulatory proteins, tetR family
NEKLCKCI_01471 3.22e-119 - - - T - - - Domain of unknown function (DUF4234)
NEKLCKCI_01472 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NEKLCKCI_01473 6.72e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEKLCKCI_01474 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEKLCKCI_01475 1.69e-182 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEKLCKCI_01476 2.56e-115 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
NEKLCKCI_01478 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEKLCKCI_01479 0.0 - - - K - - - WYL domain
NEKLCKCI_01480 2.14e-69 - - - - - - - -
NEKLCKCI_01481 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
NEKLCKCI_01482 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NEKLCKCI_01483 2.42e-182 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
NEKLCKCI_01485 3.01e-117 - - - K - - - Putative zinc ribbon domain
NEKLCKCI_01486 4.36e-162 - - - S - - - GyrI-like small molecule binding domain
NEKLCKCI_01487 2.67e-22 - - - L - - - DNA integration
NEKLCKCI_01489 8.13e-82 - - - - - - - -
NEKLCKCI_01490 1.19e-154 merR2 - - K - - - helix_turn_helix, mercury resistance
NEKLCKCI_01491 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NEKLCKCI_01492 4.58e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
NEKLCKCI_01493 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
NEKLCKCI_01494 2.27e-222 - - - S - - - Bacterial protein of unknown function (DUF881)
NEKLCKCI_01495 2.22e-151 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEKLCKCI_01496 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
NEKLCKCI_01497 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
NEKLCKCI_01498 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
NEKLCKCI_01499 1.12e-246 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEKLCKCI_01500 2.26e-210 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEKLCKCI_01501 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEKLCKCI_01502 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NEKLCKCI_01503 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEKLCKCI_01504 1.15e-165 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEKLCKCI_01505 5.17e-56 - - - - - - - -
NEKLCKCI_01506 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NEKLCKCI_01507 1.84e-316 - - - - - - - -
NEKLCKCI_01508 9.52e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEKLCKCI_01509 2.34e-284 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEKLCKCI_01510 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEKLCKCI_01511 3.73e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
NEKLCKCI_01512 6.91e-259 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEKLCKCI_01513 2.6e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEKLCKCI_01515 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NEKLCKCI_01516 2.79e-176 yebC - - K - - - transcriptional regulatory protein
NEKLCKCI_01517 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NEKLCKCI_01518 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEKLCKCI_01519 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEKLCKCI_01522 0.0 - - - - - - - -
NEKLCKCI_01526 3.94e-197 - - - S - - - PAC2 family
NEKLCKCI_01527 8.18e-216 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEKLCKCI_01528 4.73e-203 - - - G - - - Fructosamine kinase
NEKLCKCI_01529 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEKLCKCI_01530 1.54e-274 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEKLCKCI_01531 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
NEKLCKCI_01532 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEKLCKCI_01533 1.27e-181 - - - S - - - Protein of unknown function (DUF1275)
NEKLCKCI_01534 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEKLCKCI_01537 6.06e-308 - - - V - - - MatE
NEKLCKCI_01538 2.44e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEKLCKCI_01539 1.23e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEKLCKCI_01540 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
NEKLCKCI_01541 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEKLCKCI_01542 6.71e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
NEKLCKCI_01543 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NEKLCKCI_01544 4.29e-227 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NEKLCKCI_01545 3.03e-230 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
NEKLCKCI_01546 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEKLCKCI_01547 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEKLCKCI_01548 2.22e-111 - - - - - - - -
NEKLCKCI_01549 5.17e-76 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEKLCKCI_01550 1.23e-150 - - - K - - - Transcriptional regulatory protein, C terminal
NEKLCKCI_01551 0.0 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEKLCKCI_01552 6.89e-180 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NEKLCKCI_01553 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
NEKLCKCI_01554 8.31e-254 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEKLCKCI_01555 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NEKLCKCI_01556 1.41e-263 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
NEKLCKCI_01557 5.23e-277 - - - GK - - - ROK family
NEKLCKCI_01558 4.48e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEKLCKCI_01559 1.51e-264 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
NEKLCKCI_01560 3.73e-213 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NEKLCKCI_01561 3.23e-222 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEKLCKCI_01562 2.22e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEKLCKCI_01563 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEKLCKCI_01564 6.57e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEKLCKCI_01565 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEKLCKCI_01566 2.19e-291 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEKLCKCI_01567 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
NEKLCKCI_01568 1.08e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEKLCKCI_01569 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEKLCKCI_01570 1.29e-163 - - - S - - - alpha beta
NEKLCKCI_01571 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEKLCKCI_01572 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEKLCKCI_01573 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEKLCKCI_01574 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
NEKLCKCI_01575 3.59e-118 - - - - - - - -
NEKLCKCI_01576 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
NEKLCKCI_01577 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
NEKLCKCI_01578 0.0 - - - G - - - ABC transporter substrate-binding protein
NEKLCKCI_01579 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NEKLCKCI_01580 4.88e-169 - - - M - - - Peptidase family M23
NEKLCKCI_01582 1.61e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEKLCKCI_01583 4.23e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
NEKLCKCI_01584 9.87e-204 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
NEKLCKCI_01585 3.13e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
NEKLCKCI_01586 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NEKLCKCI_01587 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
NEKLCKCI_01588 4.93e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
NEKLCKCI_01589 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEKLCKCI_01590 3.75e-214 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NEKLCKCI_01591 1.72e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEKLCKCI_01592 1.72e-208 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NEKLCKCI_01593 0.0 - - - E - - - Serine carboxypeptidase
NEKLCKCI_01594 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_01595 5.73e-183 - - - S - - - Domain of unknown function (DUF4194)
NEKLCKCI_01596 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NEKLCKCI_01597 7.28e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEKLCKCI_01598 9.61e-84 - - - K - - - Protein of unknown function, DUF488
NEKLCKCI_01599 1.3e-161 - - - J - - - Acetyltransferase (GNAT) domain
NEKLCKCI_01600 5.39e-117 - - - K - - - FR47-like protein
NEKLCKCI_01601 5.46e-74 - - - K - - - Transcriptional regulator
NEKLCKCI_01602 1.32e-47 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
NEKLCKCI_01603 7.27e-28 - - - S - - - Carbon-nitrogen hydrolase
NEKLCKCI_01605 2.82e-235 - - - S - - - Acetyltransferase (GNAT) domain
NEKLCKCI_01606 3.13e-100 qseC 2.7.13.3 - T ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Histidine kinase
NEKLCKCI_01607 5.69e-170 - - - S - - - SOS response associated peptidase (SRAP)
NEKLCKCI_01608 1.35e-56 - - - - - - - -
NEKLCKCI_01610 1.6e-104 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEKLCKCI_01611 2.67e-224 - - - M - - - heme binding
NEKLCKCI_01612 2.05e-150 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NEKLCKCI_01614 2.57e-192 - - - - - - - -
NEKLCKCI_01615 1.1e-13 - - - CE ko:K03294 - ko00000 Amino acid permease
NEKLCKCI_01616 1.99e-144 - - - S - - - Putative ABC-transporter type IV
NEKLCKCI_01617 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NEKLCKCI_01618 1.31e-245 - - - V - - - VanZ like family
NEKLCKCI_01619 1.1e-188 - - - KT - - - RESPONSE REGULATOR receiver
NEKLCKCI_01620 3.34e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
NEKLCKCI_01621 3.18e-188 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
NEKLCKCI_01622 5.47e-168 - - - C - - - Putative TM nitroreductase
NEKLCKCI_01623 1.8e-159 - - - - - - - -
NEKLCKCI_01625 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
NEKLCKCI_01626 1.26e-100 - - - S - - - Bacterial PH domain
NEKLCKCI_01627 1.11e-175 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NEKLCKCI_01628 1.01e-87 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEKLCKCI_01629 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEKLCKCI_01631 1.66e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEKLCKCI_01632 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEKLCKCI_01633 2.98e-119 - - - - - - - -
NEKLCKCI_01634 7.21e-300 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEKLCKCI_01635 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
NEKLCKCI_01636 3.78e-157 - - - S - - - ABC-2 family transporter protein
NEKLCKCI_01637 6.5e-163 - - - S - - - ABC-2 family transporter protein
NEKLCKCI_01638 2.69e-228 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01639 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEKLCKCI_01640 3.05e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
NEKLCKCI_01641 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NEKLCKCI_01642 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEKLCKCI_01643 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
NEKLCKCI_01644 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NEKLCKCI_01645 1.46e-139 - - - - - - - -
NEKLCKCI_01646 3.26e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NEKLCKCI_01648 1.78e-241 - - - G - - - Haloacid dehalogenase-like hydrolase
NEKLCKCI_01649 8.79e-304 - - - L - - - Tetratricopeptide repeat
NEKLCKCI_01650 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEKLCKCI_01651 3.54e-185 - - - S - - - Putative ABC-transporter type IV
NEKLCKCI_01652 3.22e-140 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEKLCKCI_01653 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NEKLCKCI_01654 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NEKLCKCI_01655 0.0 - - - K - - - Putative DNA-binding domain
NEKLCKCI_01657 2.77e-229 - - - - - - - -
NEKLCKCI_01658 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
NEKLCKCI_01659 0.0 - - - H - - - PglZ domain
NEKLCKCI_01660 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
NEKLCKCI_01661 0.0 - - - - - - - -
NEKLCKCI_01662 0.0 - - - LV - - - DNA restriction-modification system
NEKLCKCI_01663 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NEKLCKCI_01664 5.34e-161 - - - S - - - Domain of unknown function (DUF1788)
NEKLCKCI_01665 9.57e-144 - - - S - - - Putative inner membrane protein (DUF1819)
NEKLCKCI_01666 1.11e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEKLCKCI_01667 6.9e-147 - - - S ko:K07126 - ko00000 Sel1-like repeats.
NEKLCKCI_01668 1.18e-207 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
NEKLCKCI_01669 4.56e-209 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEKLCKCI_01670 3.37e-312 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
NEKLCKCI_01671 5.23e-107 - - - - - - - -
NEKLCKCI_01672 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NEKLCKCI_01673 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
NEKLCKCI_01674 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
NEKLCKCI_01675 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
NEKLCKCI_01676 1.1e-310 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NEKLCKCI_01677 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEKLCKCI_01678 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NEKLCKCI_01679 1.61e-175 - - - S - - - UPF0126 domain
NEKLCKCI_01680 9.66e-126 - - - T - - - RNA ligase
NEKLCKCI_01681 1.65e-61 - - - S - - - phosphoesterase or phosphohydrolase
NEKLCKCI_01682 1.58e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
NEKLCKCI_01683 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEKLCKCI_01684 2.09e-242 - - - S ko:K06889 - ko00000 alpha beta
NEKLCKCI_01685 1.72e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NEKLCKCI_01686 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
NEKLCKCI_01687 3.99e-258 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
NEKLCKCI_01688 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NEKLCKCI_01689 1.96e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEKLCKCI_01690 0.0 corC - - S - - - CBS domain
NEKLCKCI_01691 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEKLCKCI_01692 2.48e-252 phoH - - T ko:K06217 - ko00000 PhoH-like protein
NEKLCKCI_01693 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NEKLCKCI_01694 2.18e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEKLCKCI_01696 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
NEKLCKCI_01697 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEKLCKCI_01698 3.49e-139 - - - S - - - Iron-sulfur cluster assembly protein
NEKLCKCI_01699 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NEKLCKCI_01700 3.1e-307 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEKLCKCI_01701 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NEKLCKCI_01702 2.5e-299 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
NEKLCKCI_01703 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
NEKLCKCI_01704 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEKLCKCI_01705 1.31e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
NEKLCKCI_01706 3.46e-154 - - - K - - - helix_turn_helix, Lux Regulon
NEKLCKCI_01707 4.78e-138 - - - - - - - -
NEKLCKCI_01708 2.27e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NEKLCKCI_01709 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEKLCKCI_01710 3.17e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEKLCKCI_01711 5.3e-69 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
NEKLCKCI_01712 4.48e-247 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEKLCKCI_01713 6.58e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEKLCKCI_01714 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEKLCKCI_01715 7.33e-50 - - - - - - - -
NEKLCKCI_01716 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
NEKLCKCI_01717 4.07e-173 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NEKLCKCI_01718 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
NEKLCKCI_01719 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEKLCKCI_01720 6.67e-173 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEKLCKCI_01721 2.18e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEKLCKCI_01722 2.46e-84 - - - S - - - Domain of unknown function (DUF4418)
NEKLCKCI_01723 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEKLCKCI_01724 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
NEKLCKCI_01725 6.52e-139 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEKLCKCI_01726 8.29e-308 pbuX - - F ko:K03458 - ko00000 Permease family
NEKLCKCI_01728 2.35e-55 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEKLCKCI_01729 5.09e-135 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEKLCKCI_01731 1.71e-144 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
NEKLCKCI_01732 9.3e-53 - - - - - - - -
NEKLCKCI_01733 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
NEKLCKCI_01734 1.8e-94 tnp3521a2 - - L - - - Integrase core domain
NEKLCKCI_01736 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
NEKLCKCI_01739 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
NEKLCKCI_01740 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEKLCKCI_01741 8e-163 gntR - - K - - - FCD
NEKLCKCI_01742 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NEKLCKCI_01745 1.56e-11 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEKLCKCI_01746 4.38e-289 - - - I - - - Serine aminopeptidase, S33
NEKLCKCI_01747 1.09e-238 - - - K - - - Periplasmic binding protein domain
NEKLCKCI_01748 7.2e-239 - - - G - - - Glycosyl hydrolases family 43
NEKLCKCI_01751 4.11e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
NEKLCKCI_01752 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEKLCKCI_01753 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEKLCKCI_01754 1.85e-123 - - - S - - - Protein of unknown function (DUF721)
NEKLCKCI_01755 5.36e-306 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEKLCKCI_01756 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEKLCKCI_01757 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEKLCKCI_01758 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NEKLCKCI_01759 2.11e-227 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
NEKLCKCI_01760 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
NEKLCKCI_01761 2.59e-162 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NEKLCKCI_01762 1.05e-229 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NEKLCKCI_01763 2.69e-310 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEKLCKCI_01764 9.66e-259 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEKLCKCI_01765 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
NEKLCKCI_01766 0.0 - - - M - - - Conserved repeat domain
NEKLCKCI_01767 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
NEKLCKCI_01768 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
NEKLCKCI_01769 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
NEKLCKCI_01770 1.32e-213 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEKLCKCI_01771 8.75e-212 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEKLCKCI_01772 3.97e-279 rpfB - - S ko:K21688 - ko00000 G5
NEKLCKCI_01774 2.47e-199 - - - O - - - Thioredoxin
NEKLCKCI_01775 0.0 - - - KLT - - - Protein tyrosine kinase
NEKLCKCI_01776 7.97e-223 - - - K - - - Psort location Cytoplasmic, score
NEKLCKCI_01777 7.3e-268 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEKLCKCI_01778 2.69e-133 - - - L - - - Helix-turn-helix domain
NEKLCKCI_01779 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
NEKLCKCI_01780 3.98e-305 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEKLCKCI_01781 5.45e-232 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NEKLCKCI_01782 3.17e-199 - - - - - - - -
NEKLCKCI_01783 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
NEKLCKCI_01784 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEKLCKCI_01786 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NEKLCKCI_01787 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
NEKLCKCI_01788 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
NEKLCKCI_01789 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
NEKLCKCI_01790 3.99e-186 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NEKLCKCI_01791 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEKLCKCI_01792 2.67e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NEKLCKCI_01793 1.7e-185 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)