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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NIPHIIMD_00001	5e-82	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIPHIIMD_00002	6.82e-230	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NIPHIIMD_00003	7.94e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NIPHIIMD_00004	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NIPHIIMD_00005	2.18e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIPHIIMD_00006	5.69e-194	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NIPHIIMD_00007	1.52e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
NIPHIIMD_00008	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
NIPHIIMD_00009	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NIPHIIMD_00010	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00011	8.58e-307	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NIPHIIMD_00012	1.01e-165	gntR	-	-	K	-	-	-	FCD
NIPHIIMD_00013	5.92e-103	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
NIPHIIMD_00014	1.13e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00015	4e-162	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_00016	2.18e-289	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00017	5.84e-293	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00018	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
NIPHIIMD_00019	3.01e-231	-	-	-	S	-	-	-	CAAX protease self-immunity
NIPHIIMD_00020	4.12e-274	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIPHIIMD_00021	2.76e-189	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00022	1.68e-205	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00023	3.99e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00024	1.56e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NIPHIIMD_00025	1.31e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NIPHIIMD_00026	3.49e-225	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NIPHIIMD_00027	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIPHIIMD_00028	6.6e-259	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NIPHIIMD_00029	2.68e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIPHIIMD_00030	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIPHIIMD_00031	3.84e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
NIPHIIMD_00032	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIPHIIMD_00035	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIPHIIMD_00036	5.69e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NIPHIIMD_00037	1.86e-242	-	-	-	-	-	-	-	-
NIPHIIMD_00038	2.15e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NIPHIIMD_00039	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_00040	7.75e-126	-	-	-	S	-	-	-	GtrA-like protein
NIPHIIMD_00041	2.72e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
NIPHIIMD_00042	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
NIPHIIMD_00043	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NIPHIIMD_00044	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NIPHIIMD_00045	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIPHIIMD_00046	1.53e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NIPHIIMD_00047	3.57e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_00048	1.67e-113	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
NIPHIIMD_00049	3.51e-272	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NIPHIIMD_00050	1.12e-48	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NIPHIIMD_00051	1.73e-61	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIPHIIMD_00052	2.1e-251	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NIPHIIMD_00053	1.05e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIPHIIMD_00054	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIPHIIMD_00055	8.84e-245	-	-	-	I	-	-	-	PAP2 superfamily
NIPHIIMD_00056	2.2e-298	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NIPHIIMD_00057	4.92e-165	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
NIPHIIMD_00058	1.61e-148	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_00059	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NIPHIIMD_00060	2.32e-39	-	-	-	-	-	-	-	-
NIPHIIMD_00061	6.91e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIPHIIMD_00062	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NIPHIIMD_00063	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIPHIIMD_00064	6.14e-146	-	-	-	S	ko:K19131	-	ko00000,ko02048	CRISPR-associated protein GSU0053 (Cas_GSU0053)
NIPHIIMD_00065	1.25e-165	-	-	-	-	ko:K19132	-	ko00000,ko02048	-
NIPHIIMD_00066	2.15e-255	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase Cas3
NIPHIIMD_00067	2.28e-117	-	-	-	-	ko:K19133	-	ko00000,ko02048	-
NIPHIIMD_00068	0.0	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIPHIIMD_00069	2.07e-14	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIPHIIMD_00070	3.88e-108	-	-	-	-	-	-	-	-
NIPHIIMD_00071	1.09e-156	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NIPHIIMD_00072	2.23e-305	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NIPHIIMD_00073	7.22e-238	-	-	-	K	-	-	-	LysR substrate binding domain protein
NIPHIIMD_00074	1.92e-199	-	-	-	S	-	-	-	Patatin-like phospholipase
NIPHIIMD_00075	1.05e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
NIPHIIMD_00076	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NIPHIIMD_00077	1.5e-29	-	-	-	S	ko:K07001	-	ko00000	lipid catabolic process
NIPHIIMD_00078	1.07e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NIPHIIMD_00079	1.8e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NIPHIIMD_00080	1.23e-150	-	-	-	S	-	-	-	Vitamin K epoxide reductase
NIPHIIMD_00081	4.79e-221	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
NIPHIIMD_00082	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
NIPHIIMD_00083	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NIPHIIMD_00084	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NIPHIIMD_00085	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NIPHIIMD_00086	9.98e-197	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NIPHIIMD_00087	1.81e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
NIPHIIMD_00089	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
NIPHIIMD_00090	1.19e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NIPHIIMD_00091	1.85e-284	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NIPHIIMD_00092	0.0	-	-	-	I	-	-	-	acetylesterase activity
NIPHIIMD_00093	4.14e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NIPHIIMD_00094	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIPHIIMD_00095	6.32e-292	-	-	-	F	-	-	-	nucleoside hydrolase
NIPHIIMD_00096	1.43e-261	-	-	-	P	-	-	-	NMT1/THI5 like
NIPHIIMD_00097	1.43e-189	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00098	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NIPHIIMD_00099	1.54e-307	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
NIPHIIMD_00100	7.57e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_00101	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
NIPHIIMD_00102	4.31e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NIPHIIMD_00103	6.69e-172	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIPHIIMD_00104	9.4e-198	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIPHIIMD_00105	0.0	-	-	-	-	-	-	-	-
NIPHIIMD_00106	3.07e-114	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NIPHIIMD_00108	1.06e-185	nfrA	-	-	C	-	-	-	Nitroreductase family
NIPHIIMD_00109	6.83e-224	-	-	-	T	-	-	-	GHKL domain
NIPHIIMD_00110	7.2e-72	-	-	-	T	-	-	-	GHKL domain
NIPHIIMD_00111	3.95e-166	-	-	-	KT	-	-	-	LytTr DNA-binding domain
NIPHIIMD_00112	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain
NIPHIIMD_00113	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 3 N terminal domain
NIPHIIMD_00114	2.08e-82	-	-	-	-	-	-	-	-
NIPHIIMD_00115	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NIPHIIMD_00116	5.15e-142	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIPHIIMD_00117	5.66e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
NIPHIIMD_00118	4.88e-177	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NIPHIIMD_00119	8.25e-43	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
NIPHIIMD_00120	8.75e-90	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_00121	4.82e-254	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_00122	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NIPHIIMD_00123	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NIPHIIMD_00124	2.94e-149	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NIPHIIMD_00125	8.59e-249	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
NIPHIIMD_00126	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
NIPHIIMD_00127	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00129	1.6e-236	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_00130	7.77e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIPHIIMD_00131	2.86e-185	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00132	1.7e-236	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_00133	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00134	1.44e-290	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
NIPHIIMD_00135	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00136	1.57e-69	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
NIPHIIMD_00137	1.81e-192	-	-	-	S	ko:K07133	-	ko00000	AAA domain
NIPHIIMD_00138	1.93e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NIPHIIMD_00139	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NIPHIIMD_00140	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NIPHIIMD_00141	1.05e-91	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIPHIIMD_00142	1.33e-231	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
NIPHIIMD_00143	1.61e-146	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
NIPHIIMD_00144	6.08e-63	-	-	-	-	-	-	-	-
NIPHIIMD_00145	1.69e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NIPHIIMD_00147	1.1e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NIPHIIMD_00148	1.54e-222	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIPHIIMD_00149	7.63e-74	-	-	-	-	-	-	-	-
NIPHIIMD_00150	7.78e-143	-	-	-	-	-	-	-	-
NIPHIIMD_00151	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIPHIIMD_00152	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NIPHIIMD_00154	1.99e-175	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
NIPHIIMD_00155	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00156	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00157	7.32e-165	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NIPHIIMD_00158	6.62e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NIPHIIMD_00159	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NIPHIIMD_00160	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NIPHIIMD_00161	1.1e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
NIPHIIMD_00162	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
NIPHIIMD_00163	5.16e-271	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_00164	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
NIPHIIMD_00165	1.35e-240	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIPHIIMD_00166	3.73e-306	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NIPHIIMD_00167	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIPHIIMD_00168	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NIPHIIMD_00169	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
NIPHIIMD_00170	1.62e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
NIPHIIMD_00172	1.41e-156	-	-	-	S	-	-	-	CYTH
NIPHIIMD_00173	2.25e-217	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
NIPHIIMD_00174	1.19e-233	-	-	-	-	-	-	-	-
NIPHIIMD_00175	1.35e-266	-	-	-	-	-	-	-	-
NIPHIIMD_00176	9.63e-194	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
NIPHIIMD_00177	1.32e-156	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NIPHIIMD_00178	2.85e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NIPHIIMD_00179	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIPHIIMD_00180	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIPHIIMD_00181	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIPHIIMD_00182	2.31e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIPHIIMD_00183	3.7e-92	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIPHIIMD_00184	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIPHIIMD_00185	6.89e-190	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NIPHIIMD_00186	1.2e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIPHIIMD_00188	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NIPHIIMD_00189	4.96e-249	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NIPHIIMD_00190	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
NIPHIIMD_00191	3.8e-224	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIPHIIMD_00192	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NIPHIIMD_00193	2.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIPHIIMD_00194	7.04e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NIPHIIMD_00195	1.09e-173	-	-	-	-	-	-	-	-
NIPHIIMD_00197	3.34e-174	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00198	1.05e-30	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NIPHIIMD_00199	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00200	4.24e-246	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NIPHIIMD_00201	3.68e-96	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NIPHIIMD_00202	2.48e-295	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
NIPHIIMD_00203	4.54e-214	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NIPHIIMD_00204	1.41e-128	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
NIPHIIMD_00206	9.65e-56	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NIPHIIMD_00208	4.12e-253	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
NIPHIIMD_00210	8.4e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIPHIIMD_00211	1.05e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIPHIIMD_00212	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NIPHIIMD_00213	6.16e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIPHIIMD_00214	2.51e-200	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
NIPHIIMD_00215	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
NIPHIIMD_00216	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NIPHIIMD_00217	1.07e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_00218	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
NIPHIIMD_00219	8.11e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_00220	5.39e-308	-	-	-	G	-	-	-	Transporter major facilitator family protein
NIPHIIMD_00221	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
NIPHIIMD_00222	1.9e-174	-	-	-	K	-	-	-	transcriptional regulator
NIPHIIMD_00223	9.1e-286	-	-	-	G	-	-	-	MFS/sugar transport protein
NIPHIIMD_00224	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
NIPHIIMD_00225	0.0	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NIPHIIMD_00226	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
NIPHIIMD_00227	9.32e-312	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NIPHIIMD_00228	3.02e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_00229	3.21e-288	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
NIPHIIMD_00230	5.06e-280	-	-	-	P	-	-	-	Major Facilitator Superfamily
NIPHIIMD_00231	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
NIPHIIMD_00232	9.94e-54	-	-	-	-	-	-	-	-
NIPHIIMD_00233	5.87e-247	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NIPHIIMD_00234	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00235	8.33e-254	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_00236	5.4e-309	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NIPHIIMD_00237	1.21e-211	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NIPHIIMD_00238	2.41e-169	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NIPHIIMD_00239	3.01e-312	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
NIPHIIMD_00240	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NIPHIIMD_00241	2.52e-63	-	-	-	-	-	-	-	-
NIPHIIMD_00242	1.85e-240	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
NIPHIIMD_00243	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
NIPHIIMD_00244	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NIPHIIMD_00245	2.2e-242	-	-	-	-	-	-	-	-
NIPHIIMD_00246	3.71e-182	-	-	-	V	-	-	-	Abi-like protein
NIPHIIMD_00247	4.62e-50	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NIPHIIMD_00248	9.08e-149	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NIPHIIMD_00250	4.04e-226	-	-	-	S	-	-	-	EpsG family
NIPHIIMD_00251	2.55e-07	-	-	-	-	-	-	-	-
NIPHIIMD_00252	1.86e-245	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00253	2.02e-270	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NIPHIIMD_00254	1.37e-141	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
NIPHIIMD_00255	3.16e-252	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
NIPHIIMD_00256	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NIPHIIMD_00257	6.01e-309	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NIPHIIMD_00258	1.61e-258	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00259	2.79e-242	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
NIPHIIMD_00260	1.58e-254	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NIPHIIMD_00262	2.59e-33	-	-	-	M	-	-	-	Glycosyl transferase family 8
NIPHIIMD_00263	2.47e-70	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NIPHIIMD_00264	5.53e-106	-	-	-	M	-	-	-	Glycosyl transferases group 1
NIPHIIMD_00265	3.06e-28	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NIPHIIMD_00267	1.14e-18	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIPHIIMD_00268	3.55e-131	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NIPHIIMD_00271	7.7e-63	-	-	-	-	-	-	-	-
NIPHIIMD_00276	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NIPHIIMD_00277	2.49e-261	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NIPHIIMD_00278	2.21e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIPHIIMD_00279	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NIPHIIMD_00280	2.12e-233	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPHIIMD_00281	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPHIIMD_00282	1.99e-40	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NIPHIIMD_00283	5.58e-249	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_00284	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
NIPHIIMD_00285	9.39e-149	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NIPHIIMD_00286	0.0	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NIPHIIMD_00287	1.06e-296	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00288	4.35e-210	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00289	7.4e-193	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00290	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
NIPHIIMD_00291	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NIPHIIMD_00292	2.65e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NIPHIIMD_00294	1.07e-159	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NIPHIIMD_00295	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
NIPHIIMD_00296	2.35e-52	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
NIPHIIMD_00297	3.44e-239	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_00298	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
NIPHIIMD_00299	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIPHIIMD_00300	2.01e-309	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
NIPHIIMD_00301	2.32e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00302	1.58e-235	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIPHIIMD_00303	0.0	-	-	-	M	-	-	-	domain protein
NIPHIIMD_00304	3.46e-278	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NIPHIIMD_00305	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00306	3.34e-193	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NIPHIIMD_00307	5.55e-66	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
NIPHIIMD_00308	1.44e-72	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
NIPHIIMD_00309	6.49e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
NIPHIIMD_00310	5.78e-296	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NIPHIIMD_00311	1.48e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIPHIIMD_00312	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
NIPHIIMD_00313	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIPHIIMD_00314	4.34e-169	-	-	-	K	-	-	-	LytTr DNA-binding domain
NIPHIIMD_00315	0.0	-	-	-	T	-	-	-	GHKL domain
NIPHIIMD_00316	2.68e-139	-	-	-	-	-	-	-	-
NIPHIIMD_00317	1.69e-273	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NIPHIIMD_00318	2.72e-63	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
NIPHIIMD_00319	3.49e-175	-	-	-	-	-	-	-	-
NIPHIIMD_00320	4.61e-208	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIPHIIMD_00321	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIPHIIMD_00322	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
NIPHIIMD_00324	9.34e-130	-	-	-	S	-	-	-	GtrA-like protein
NIPHIIMD_00325	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NIPHIIMD_00326	1.72e-151	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
NIPHIIMD_00327	1.9e-104	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00328	2.15e-146	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_00329	4.77e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NIPHIIMD_00330	3.81e-305	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIPHIIMD_00331	3.12e-41	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NIPHIIMD_00332	1.91e-54	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NIPHIIMD_00333	2.7e-296	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NIPHIIMD_00334	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NIPHIIMD_00335	1.79e-101	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NIPHIIMD_00339	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NIPHIIMD_00340	4.73e-267	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NIPHIIMD_00341	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NIPHIIMD_00342	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
NIPHIIMD_00343	1.13e-270	dapC	-	-	E	-	-	-	Aminotransferase class I and II
NIPHIIMD_00344	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NIPHIIMD_00345	2.8e-231	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00346	9.34e-179	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00347	1.45e-198	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NIPHIIMD_00348	1.82e-195	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIPHIIMD_00349	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NIPHIIMD_00350	0.000251	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	family 2 sugar binding
NIPHIIMD_00351	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00352	1.13e-298	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
NIPHIIMD_00353	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
NIPHIIMD_00354	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
NIPHIIMD_00356	1.14e-310	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIPHIIMD_00357	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
NIPHIIMD_00358	2.13e-254	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIPHIIMD_00359	7.75e-145	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
NIPHIIMD_00360	1.44e-150	-	-	-	-	-	-	-	-
NIPHIIMD_00361	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NIPHIIMD_00362	2.26e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIPHIIMD_00363	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NIPHIIMD_00364	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NIPHIIMD_00365	2.55e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPHIIMD_00366	2.35e-274	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NIPHIIMD_00368	3.12e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIPHIIMD_00369	2.02e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIPHIIMD_00370	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NIPHIIMD_00372	3.62e-287	xylR	-	-	GK	-	-	-	ROK family
NIPHIIMD_00373	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NIPHIIMD_00374	4.05e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
NIPHIIMD_00375	3.07e-11	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
NIPHIIMD_00376	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
NIPHIIMD_00377	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NIPHIIMD_00378	4.06e-212	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00379	9.8e-236	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00380	7.57e-304	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
NIPHIIMD_00381	1.52e-239	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NIPHIIMD_00382	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NIPHIIMD_00383	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NIPHIIMD_00384	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
NIPHIIMD_00385	0.0	-	-	-	S	-	-	-	Amidohydrolase family
NIPHIIMD_00386	5.56e-64	-	-	-	S	-	-	-	Protein conserved in bacteria
NIPHIIMD_00387	2.98e-197	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
NIPHIIMD_00388	2.49e-95	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIPHIIMD_00389	1.9e-231	-	-	-	V	-	-	-	Beta-lactamase
NIPHIIMD_00390	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
NIPHIIMD_00391	7.05e-215	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
NIPHIIMD_00392	2.57e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
NIPHIIMD_00393	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIPHIIMD_00394	6.95e-204	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIPHIIMD_00395	3.24e-52	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NIPHIIMD_00396	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00397	0.0	abfA1	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
NIPHIIMD_00398	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00399	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_00400	8.68e-48	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NIPHIIMD_00401	6.69e-94	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
NIPHIIMD_00402	8.45e-184	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NIPHIIMD_00403	2.21e-106	-	-	-	S	-	-	-	SnoaL-like domain
NIPHIIMD_00404	2.71e-185	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NIPHIIMD_00405	1.97e-307	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIPHIIMD_00406	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NIPHIIMD_00407	8.06e-213	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00408	5.4e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00409	4.79e-177	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
NIPHIIMD_00410	1.03e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00411	1.16e-242	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NIPHIIMD_00412	4.19e-283	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NIPHIIMD_00413	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00414	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NIPHIIMD_00415	1.29e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIPHIIMD_00416	4.58e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIPHIIMD_00417	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NIPHIIMD_00418	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIPHIIMD_00419	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIPHIIMD_00420	4.28e-274	-	-	-	P	-	-	-	Citrate transporter
NIPHIIMD_00422	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NIPHIIMD_00426	2.14e-130	-	-	-	K	-	-	-	acetyltransferase
NIPHIIMD_00427	5.59e-141	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00428	3.03e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00429	2.39e-192	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
NIPHIIMD_00430	2.05e-203	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NIPHIIMD_00431	3.63e-257	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIPHIIMD_00432	4.32e-200	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NIPHIIMD_00433	9.19e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIPHIIMD_00434	4.35e-134	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
NIPHIIMD_00435	1.16e-284	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NIPHIIMD_00436	2.19e-98	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NIPHIIMD_00437	9.91e-22	-	-	-	P	-	-	-	Belongs to the ABC transporter superfamily
NIPHIIMD_00438	7.85e-59	-	-	-	O	-	-	-	Glutaredoxin
NIPHIIMD_00439	1.89e-178	hflK	-	-	O	-	-	-	prohibitin homologues
NIPHIIMD_00440	8.71e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NIPHIIMD_00441	7e-99	-	-	-	-	-	-	-	-
NIPHIIMD_00442	1.97e-172	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00443	1.55e-206	-	-	-	M	-	-	-	Conserved repeat domain
NIPHIIMD_00444	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NIPHIIMD_00445	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIPHIIMD_00446	3.84e-233	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
NIPHIIMD_00447	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIPHIIMD_00448	3.33e-287	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIPHIIMD_00449	7.41e-117	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NIPHIIMD_00450	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NIPHIIMD_00451	1.15e-259	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NIPHIIMD_00452	4.55e-242	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
NIPHIIMD_00453	1.06e-165	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
NIPHIIMD_00454	2.58e-274	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
NIPHIIMD_00455	1.98e-38	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NIPHIIMD_00456	5.59e-185	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NIPHIIMD_00457	5.47e-314	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_00458	5.93e-299	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NIPHIIMD_00459	1.07e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NIPHIIMD_00460	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIPHIIMD_00461	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
NIPHIIMD_00462	3.2e-49	-	-	-	-	-	-	-	-
NIPHIIMD_00463	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NIPHIIMD_00464	1.97e-175	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NIPHIIMD_00465	2.1e-289	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIPHIIMD_00466	1.78e-287	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NIPHIIMD_00467	8.99e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NIPHIIMD_00469	5.25e-241	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
NIPHIIMD_00471	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIPHIIMD_00472	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIPHIIMD_00473	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIPHIIMD_00474	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIPHIIMD_00475	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIPHIIMD_00476	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIPHIIMD_00477	2.95e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NIPHIIMD_00478	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NIPHIIMD_00479	1.42e-218	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NIPHIIMD_00480	2.55e-137	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NIPHIIMD_00482	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NIPHIIMD_00483	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIPHIIMD_00484	7.42e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIPHIIMD_00485	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIPHIIMD_00486	1.23e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NIPHIIMD_00487	1.01e-228	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIPHIIMD_00488	1.29e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
NIPHIIMD_00489	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
NIPHIIMD_00490	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
NIPHIIMD_00491	8.18e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NIPHIIMD_00492	5.14e-34	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NIPHIIMD_00493	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NIPHIIMD_00494	7.66e-181	-	-	-	C	-	-	-	FMN binding
NIPHIIMD_00495	1.11e-77	-	-	-	-	-	-	-	-
NIPHIIMD_00496	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
NIPHIIMD_00497	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
NIPHIIMD_00498	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
NIPHIIMD_00499	0.0	-	-	-	S	-	-	-	PGAP1-like protein
NIPHIIMD_00500	2.86e-103	-	-	-	-	-	-	-	-
NIPHIIMD_00501	5.88e-233	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NIPHIIMD_00502	5.1e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NIPHIIMD_00503	3.29e-121	-	-	-	-	-	-	-	-
NIPHIIMD_00504	8.61e-224	-	-	-	S	-	-	-	Protein of unknown function DUF58
NIPHIIMD_00505	1.31e-233	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NIPHIIMD_00506	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIPHIIMD_00507	4e-116	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NIPHIIMD_00508	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIPHIIMD_00509	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
NIPHIIMD_00510	8.75e-169	-	-	-	-	-	-	-	-
NIPHIIMD_00511	2.04e-169	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
NIPHIIMD_00512	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIPHIIMD_00513	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NIPHIIMD_00514	1.23e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
NIPHIIMD_00515	1.36e-242	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
NIPHIIMD_00516	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
NIPHIIMD_00517	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NIPHIIMD_00518	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
NIPHIIMD_00519	7.96e-316	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
NIPHIIMD_00520	1.71e-180	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
NIPHIIMD_00521	1.25e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
NIPHIIMD_00522	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NIPHIIMD_00523	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NIPHIIMD_00524	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00525	1.01e-179	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00526	7.87e-186	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
NIPHIIMD_00527	1.25e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NIPHIIMD_00528	1.04e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00529	3.03e-258	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00530	4.93e-244	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NIPHIIMD_00531	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
NIPHIIMD_00532	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
NIPHIIMD_00533	3.27e-171	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NIPHIIMD_00534	0.0	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIPHIIMD_00535	0.0	lpqB	-	-	S	-	-	-	Lipoprotein LpqB beta-propeller domain
NIPHIIMD_00536	2.53e-218	-	-	-	G	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
NIPHIIMD_00537	0.0	-	3.6.3.17	-	G	ko:K02056,ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00538	2.87e-231	ytfT	-	-	U	ko:K02057,ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NIPHIIMD_00539	1.77e-219	-	-	-	U	ko:K02057,ko:K10440,ko:K17209	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
NIPHIIMD_00540	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_00541	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NIPHIIMD_00542	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIPHIIMD_00543	9.35e-161	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIPHIIMD_00544	5.76e-308	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIPHIIMD_00547	2.92e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIPHIIMD_00548	1.23e-151	safC	-	-	S	-	-	-	O-methyltransferase
NIPHIIMD_00549	1.38e-225	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NIPHIIMD_00550	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
NIPHIIMD_00551	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NIPHIIMD_00552	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NIPHIIMD_00553	1.85e-108	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
NIPHIIMD_00554	8.71e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NIPHIIMD_00555	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
NIPHIIMD_00556	1.88e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NIPHIIMD_00557	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NIPHIIMD_00558	1.1e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NIPHIIMD_00559	2.42e-245	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
NIPHIIMD_00560	1.28e-182	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_00561	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NIPHIIMD_00562	1.74e-168	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NIPHIIMD_00563	0.0	-	-	-	T	-	-	-	Histidine kinase
NIPHIIMD_00564	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
NIPHIIMD_00565	1.04e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIPHIIMD_00566	3.03e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIPHIIMD_00567	6.19e-24	yccF	-	-	S	-	-	-	Inner membrane component domain
NIPHIIMD_00568	2.7e-17	-	-	-	-	-	-	-	-
NIPHIIMD_00569	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NIPHIIMD_00570	5.76e-134	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
NIPHIIMD_00571	5.47e-270	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
NIPHIIMD_00573	4.06e-180	-	-	-	-	-	-	-	-
NIPHIIMD_00575	3.23e-225	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NIPHIIMD_00576	1.01e-287	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
NIPHIIMD_00577	1.46e-209	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
NIPHIIMD_00578	5.87e-104	-	-	-	F	-	-	-	uridine kinase
NIPHIIMD_00579	4.4e-104	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NIPHIIMD_00580	4.58e-184	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NIPHIIMD_00581	1.91e-181	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NIPHIIMD_00582	5.52e-201	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NIPHIIMD_00583	2.03e-290	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
NIPHIIMD_00584	2.2e-163	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NIPHIIMD_00585	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
NIPHIIMD_00586	3.34e-173	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NIPHIIMD_00587	3.89e-180	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00588	1.59e-304	-	-	-	S	-	-	-	Putative esterase
NIPHIIMD_00589	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
NIPHIIMD_00590	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIPHIIMD_00591	2.06e-189	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPHIIMD_00592	9.4e-301	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NIPHIIMD_00593	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIPHIIMD_00594	5.43e-233	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
NIPHIIMD_00595	4.99e-188	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NIPHIIMD_00596	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_00597	1.9e-104	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIPHIIMD_00598	3.49e-134	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NIPHIIMD_00599	1.21e-121	-	-	-	E	-	-	-	AzlC protein
NIPHIIMD_00601	1.32e-69	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NIPHIIMD_00602	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
NIPHIIMD_00603	1.2e-53	-	-	-	S	-	-	-	Selenoprotein, putative
NIPHIIMD_00604	2.63e-228	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NIPHIIMD_00605	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NIPHIIMD_00606	1.39e-128	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NIPHIIMD_00607	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIPHIIMD_00608	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIPHIIMD_00609	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIPHIIMD_00610	4.86e-97	-	-	-	D	-	-	-	Septum formation initiator
NIPHIIMD_00611	1.37e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
NIPHIIMD_00612	4.49e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NIPHIIMD_00614	9.11e-120	-	-	-	-	-	-	-	-
NIPHIIMD_00615	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NIPHIIMD_00616	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
NIPHIIMD_00617	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIPHIIMD_00618	1.34e-200	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NIPHIIMD_00619	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIPHIIMD_00620	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIPHIIMD_00621	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NIPHIIMD_00622	6.58e-219	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NIPHIIMD_00624	7.96e-298	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NIPHIIMD_00625	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIPHIIMD_00626	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
NIPHIIMD_00627	3.77e-290	-	-	-	-	-	-	-	-
NIPHIIMD_00628	1.02e-91	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NIPHIIMD_00629	2.56e-196	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
NIPHIIMD_00630	1.14e-176	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
NIPHIIMD_00631	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIPHIIMD_00632	1.74e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
NIPHIIMD_00633	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NIPHIIMD_00634	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
NIPHIIMD_00635	3.22e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NIPHIIMD_00636	3.19e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NIPHIIMD_00637	7.98e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00638	9.56e-230	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NIPHIIMD_00639	8.17e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIPHIIMD_00640	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NIPHIIMD_00641	1.09e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIPHIIMD_00642	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIPHIIMD_00643	2.78e-225	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
NIPHIIMD_00644	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
NIPHIIMD_00646	1.44e-25	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NIPHIIMD_00648	8.69e-249	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NIPHIIMD_00649	3.03e-147	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00650	7.84e-159	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
NIPHIIMD_00651	2.6e-131	tcyA/tcyB	-	-	E	ko:K02029,ko:K02030,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_00652	1.68e-44	-	-	-	F	-	-	-	DNA helicase
NIPHIIMD_00653	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NIPHIIMD_00654	9.48e-308	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
NIPHIIMD_00655	1.93e-64	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
NIPHIIMD_00656	2.42e-133	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIPHIIMD_00657	3.07e-75	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
NIPHIIMD_00658	1.85e-202	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NIPHIIMD_00659	8.64e-156	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
NIPHIIMD_00660	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIPHIIMD_00661	1.74e-222	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
NIPHIIMD_00662	4.34e-159	-	-	-	L	-	-	-	NUDIX domain
NIPHIIMD_00663	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NIPHIIMD_00664	3.23e-269	-	-	-	-	-	-	-	-
NIPHIIMD_00666	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NIPHIIMD_00668	4.56e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIPHIIMD_00669	1.33e-99	-	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NIPHIIMD_00670	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NIPHIIMD_00671	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIPHIIMD_00672	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
NIPHIIMD_00673	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIPHIIMD_00674	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NIPHIIMD_00675	2.37e-309	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
NIPHIIMD_00676	4.41e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIPHIIMD_00677	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NIPHIIMD_00678	3.23e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
NIPHIIMD_00679	7.13e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIPHIIMD_00680	6.35e-193	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIPHIIMD_00681	3.17e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIPHIIMD_00682	1.97e-74	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NIPHIIMD_00683	9.46e-167	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NIPHIIMD_00684	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
NIPHIIMD_00685	6.83e-50	-	-	-	-	-	-	-	-
NIPHIIMD_00686	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIPHIIMD_00687	1.06e-106	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIPHIIMD_00688	2.36e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIPHIIMD_00689	3.69e-95	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NIPHIIMD_00690	1.64e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIPHIIMD_00691	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIPHIIMD_00692	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NIPHIIMD_00693	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
NIPHIIMD_00694	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIPHIIMD_00695	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NIPHIIMD_00696	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
NIPHIIMD_00697	5.26e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
NIPHIIMD_00698	1.14e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NIPHIIMD_00699	3.08e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIPHIIMD_00700	1.5e-130	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NIPHIIMD_00701	1.6e-140	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NIPHIIMD_00702	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NIPHIIMD_00703	5e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
NIPHIIMD_00705	9.78e-188	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIPHIIMD_00706	8.96e-75	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NIPHIIMD_00707	2.86e-267	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
NIPHIIMD_00708	1.14e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIPHIIMD_00709	0.0	corC	-	-	S	-	-	-	CBS domain
NIPHIIMD_00710	3.01e-227	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIPHIIMD_00711	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NIPHIIMD_00712	3.43e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
NIPHIIMD_00713	1.02e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
NIPHIIMD_00714	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NIPHIIMD_00715	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00717	7.88e-287	-	-	-	G	-	-	-	Transmembrane secretion effector
NIPHIIMD_00718	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_00719	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NIPHIIMD_00720	2.67e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NIPHIIMD_00721	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIPHIIMD_00723	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIPHIIMD_00724	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIPHIIMD_00725	3.74e-41	-	-	-	EGP	ko:K08177,ko:K19577	-	ko00000,ko02000	Major facilitator Superfamily
NIPHIIMD_00726	9.97e-36	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
NIPHIIMD_00727	1.08e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NIPHIIMD_00728	1.29e-127	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NIPHIIMD_00729	2.44e-120	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPHIIMD_00730	1e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPHIIMD_00731	1.11e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIPHIIMD_00733	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
NIPHIIMD_00734	3.02e-174	-	-	-	S	-	-	-	UPF0126 domain
NIPHIIMD_00735	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NIPHIIMD_00736	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIPHIIMD_00737	3.15e-298	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NIPHIIMD_00738	9.78e-188	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
NIPHIIMD_00739	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
NIPHIIMD_00740	7.44e-278	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
NIPHIIMD_00741	2.23e-297	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NIPHIIMD_00742	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
NIPHIIMD_00743	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NIPHIIMD_00744	3.85e-98	-	-	-	-	-	-	-	-
NIPHIIMD_00745	0.0	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
NIPHIIMD_00746	2.73e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00747	9.73e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NIPHIIMD_00748	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
NIPHIIMD_00749	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIPHIIMD_00750	5.54e-200	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NIPHIIMD_00751	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NIPHIIMD_00752	8.48e-241	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NIPHIIMD_00753	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NIPHIIMD_00754	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIPHIIMD_00755	1.44e-228	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
NIPHIIMD_00756	5.08e-198	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NIPHIIMD_00757	8.22e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIPHIIMD_00758	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIPHIIMD_00759	1.88e-222	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NIPHIIMD_00760	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NIPHIIMD_00761	9.59e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NIPHIIMD_00762	4.36e-89	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIPHIIMD_00763	9.38e-279	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00764	1.49e-156	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NIPHIIMD_00765	1.06e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NIPHIIMD_00766	6.85e-179	-	-	-	S	-	-	-	SdpI/YhfL protein family
NIPHIIMD_00767	7.54e-156	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NIPHIIMD_00768	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIPHIIMD_00769	5.36e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIPHIIMD_00772	2.45e-81	-	-	-	-	-	-	-	-
NIPHIIMD_00773	9.76e-125	-	-	-	M	-	-	-	Peptidase family M23
NIPHIIMD_00774	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NIPHIIMD_00775	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
NIPHIIMD_00776	1.58e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
NIPHIIMD_00777	1.07e-265	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
NIPHIIMD_00778	5.78e-139	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
NIPHIIMD_00779	3.58e-93	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIPHIIMD_00780	3.3e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIPHIIMD_00781	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIPHIIMD_00782	7.33e-183	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NIPHIIMD_00783	2.19e-170	-	-	-	-	-	-	-	-
NIPHIIMD_00785	1.2e-298	-	-	-	K	-	-	-	Fic/DOC family
NIPHIIMD_00786	4.75e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
NIPHIIMD_00787	0.0	-	-	-	M	-	-	-	domain protein
NIPHIIMD_00790	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NIPHIIMD_00791	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NIPHIIMD_00792	1.93e-182	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NIPHIIMD_00793	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NIPHIIMD_00794	4.58e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
NIPHIIMD_00795	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NIPHIIMD_00796	3.52e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NIPHIIMD_00797	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NIPHIIMD_00798	6.89e-190	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
NIPHIIMD_00799	7.04e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
NIPHIIMD_00800	1.13e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIPHIIMD_00802	4.62e-152	yoaP	-	-	E	-	-	-	YoaP-like
NIPHIIMD_00803	7.51e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIPHIIMD_00804	3.51e-154	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NIPHIIMD_00805	2.39e-93	-	-	-	K	-	-	-	MerR family regulatory protein
NIPHIIMD_00806	2.21e-253	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NIPHIIMD_00807	3.77e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NIPHIIMD_00808	1.24e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00809	5.77e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIPHIIMD_00810	5.23e-233	-	-	-	P	-	-	-	Cation efflux family
NIPHIIMD_00813	1.62e-141	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
NIPHIIMD_00814	3.21e-195	-	-	-	-	-	-	-	-
NIPHIIMD_00815	7.76e-186	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00816	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NIPHIIMD_00817	6.85e-216	-	-	-	S	-	-	-	IMP dehydrogenase activity
NIPHIIMD_00818	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NIPHIIMD_00819	4.74e-145	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
NIPHIIMD_00820	4.53e-88	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIPHIIMD_00822	2.77e-19	-	-	-	-	-	-	-	-
NIPHIIMD_00823	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00824	6.85e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
NIPHIIMD_00825	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00826	2.14e-282	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00827	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIPHIIMD_00828	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIPHIIMD_00829	1.7e-233	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
NIPHIIMD_00830	7.62e-219	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NIPHIIMD_00831	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NIPHIIMD_00832	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NIPHIIMD_00833	3.29e-190	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIPHIIMD_00834	2.47e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NIPHIIMD_00835	4.46e-226	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIPHIIMD_00836	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
NIPHIIMD_00837	3.51e-11	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
NIPHIIMD_00838	3.14e-39	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
NIPHIIMD_00839	3.29e-89	-	-	-	H	ko:K03811	-	ko00000,ko02000	Nicotinamide mononucleotide transporter
NIPHIIMD_00840	4.03e-57	nadR	-	-	H	-	-	-	ATPase kinase involved in NAD metabolism
NIPHIIMD_00841	4.69e-260	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIPHIIMD_00842	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
NIPHIIMD_00843	1.32e-249	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIPHIIMD_00844	6.98e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIPHIIMD_00845	1.58e-201	-	-	-	G	-	-	-	Fructosamine kinase
NIPHIIMD_00846	1.44e-199	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIPHIIMD_00847	3.95e-200	-	-	-	S	-	-	-	PAC2 family
NIPHIIMD_00855	3.74e-48	-	-	-	-	-	-	-	-
NIPHIIMD_00856	2.22e-98	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NIPHIIMD_00857	5.29e-145	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NIPHIIMD_00858	1.54e-80	-	-	-	-	-	-	-	-
NIPHIIMD_00859	5.93e-181	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NIPHIIMD_00860	2.24e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NIPHIIMD_00861	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
NIPHIIMD_00862	2.4e-73	-	-	-	-	-	-	-	-
NIPHIIMD_00863	0.0	-	-	-	K	-	-	-	WYL domain
NIPHIIMD_00864	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NIPHIIMD_00866	8.64e-92	-	-	-	-	-	-	-	-
NIPHIIMD_00867	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NIPHIIMD_00868	9.79e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NIPHIIMD_00869	8.38e-208	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NIPHIIMD_00870	1.69e-48	-	-	-	-	-	-	-	-
NIPHIIMD_00871	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NIPHIIMD_00872	0.0	-	-	-	-	-	-	-	-
NIPHIIMD_00873	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NIPHIIMD_00874	2.23e-280	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NIPHIIMD_00875	5.27e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIPHIIMD_00876	3.98e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NIPHIIMD_00877	3.38e-256	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIPHIIMD_00878	1.34e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIPHIIMD_00879	2.73e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NIPHIIMD_00880	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NIPHIIMD_00881	2.88e-144	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
NIPHIIMD_00882	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIPHIIMD_00883	3.22e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NIPHIIMD_00884	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
NIPHIIMD_00885	7.61e-221	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NIPHIIMD_00886	8.44e-134	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIPHIIMD_00887	1.24e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NIPHIIMD_00888	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
NIPHIIMD_00889	2.25e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
NIPHIIMD_00890	3.4e-231	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIPHIIMD_00891	2.25e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIPHIIMD_00892	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIPHIIMD_00893	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIPHIIMD_00894	1.12e-95	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIPHIIMD_00895	5.63e-178	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIPHIIMD_00896	1.12e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIPHIIMD_00897	5.62e-228	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NIPHIIMD_00898	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIPHIIMD_00899	2.04e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NIPHIIMD_00901	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIPHIIMD_00902	7.95e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NIPHIIMD_00903	1.49e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIPHIIMD_00904	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
NIPHIIMD_00905	1.25e-157	-	-	-	-	-	-	-	-
NIPHIIMD_00907	1.67e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIPHIIMD_00908	1.1e-180	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIPHIIMD_00909	5.54e-131	-	-	-	-	-	-	-	-
NIPHIIMD_00910	4.12e-310	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIPHIIMD_00911	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIPHIIMD_00912	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
NIPHIIMD_00913	2.93e-297	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
NIPHIIMD_00914	1.49e-138	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NIPHIIMD_00915	1.96e-222	-	-	-	G	-	-	-	Fic/DOC family
NIPHIIMD_00916	4.53e-181	-	-	-	-	-	-	-	-
NIPHIIMD_00917	9.96e-209	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
NIPHIIMD_00918	1.04e-213	-	-	-	S	-	-	-	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIPHIIMD_00919	2.83e-99	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIPHIIMD_00921	1.5e-118	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
NIPHIIMD_00922	5.7e-06	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NIPHIIMD_00923	3.11e-124	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NIPHIIMD_00924	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
NIPHIIMD_00925	1.13e-59	-	-	-	L	-	-	-	transposition
NIPHIIMD_00926	2.13e-30	-	-	-	C	-	-	-	Acetamidase/Formamidase family
NIPHIIMD_00927	5.29e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NIPHIIMD_00928	1.95e-221	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00929	1.47e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
NIPHIIMD_00930	2.06e-157	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NIPHIIMD_00931	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NIPHIIMD_00932	2.71e-228	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIPHIIMD_00933	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
NIPHIIMD_00934	1.25e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NIPHIIMD_00935	4.79e-173	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NIPHIIMD_00936	1.26e-244	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
NIPHIIMD_00937	8.02e-231	-	-	-	L	-	-	-	Tetratricopeptide repeat
NIPHIIMD_00938	9.56e-317	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIPHIIMD_00939	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NIPHIIMD_00940	1.67e-180	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NIPHIIMD_00941	2.36e-122	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIPHIIMD_00942	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NIPHIIMD_00943	4.33e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIPHIIMD_00944	1.15e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NIPHIIMD_00945	9.86e-237	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIPHIIMD_00946	2.88e-307	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NIPHIIMD_00947	8.32e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NIPHIIMD_00948	5.78e-268	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIPHIIMD_00949	1.16e-263	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIPHIIMD_00950	7.69e-148	-	-	-	-	-	-	-	-
NIPHIIMD_00951	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
NIPHIIMD_00952	9.1e-261	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIPHIIMD_00953	2.23e-201	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIPHIIMD_00954	6.62e-128	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
NIPHIIMD_00956	2.06e-25	-	-	-	-	-	-	-	-
NIPHIIMD_00958	2.76e-15	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
NIPHIIMD_00959	2.27e-146	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
NIPHIIMD_00960	1.52e-19	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NIPHIIMD_00961	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NIPHIIMD_00962	1.29e-185	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
NIPHIIMD_00963	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIPHIIMD_00964	1.52e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
NIPHIIMD_00965	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
NIPHIIMD_00966	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NIPHIIMD_00967	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00968	3.77e-109	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NIPHIIMD_00969	3.91e-259	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NIPHIIMD_00970	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIPHIIMD_00971	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NIPHIIMD_00972	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIPHIIMD_00973	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
NIPHIIMD_00974	6.33e-186	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_00975	8.28e-281	-	-	-	E	-	-	-	Aminotransferase class I and II
NIPHIIMD_00976	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NIPHIIMD_00977	9.03e-258	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NIPHIIMD_00978	9.48e-190	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIPHIIMD_00979	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
NIPHIIMD_00980	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_00981	3.95e-139	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIPHIIMD_00982	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_00983	6.53e-53	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	homocysteine catabolic process
NIPHIIMD_00984	4.94e-149	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
NIPHIIMD_00985	1.64e-239	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NIPHIIMD_00986	6.33e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIPHIIMD_00987	8.87e-160	-	-	-	S	-	-	-	alpha beta
NIPHIIMD_00989	1.3e-72	-	-	-	S	-	-	-	Protein of unknown function DUF262
NIPHIIMD_00990	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NIPHIIMD_00991	0.0	-	-	-	L	-	-	-	UvrD-like helicase C-terminal domain
NIPHIIMD_00992	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
NIPHIIMD_00993	0.0	-	-	-	V	-	-	-	Type II restriction enzyme, methylase
NIPHIIMD_00994	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NIPHIIMD_00997	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NIPHIIMD_00998	2.02e-269	-	-	-	GK	-	-	-	ROK family
NIPHIIMD_00999	6.67e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01000	7.7e-196	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01001	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NIPHIIMD_01002	5.59e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NIPHIIMD_01003	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NIPHIIMD_01004	1.57e-191	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIPHIIMD_01005	1.41e-306	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NIPHIIMD_01006	2.4e-240	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIPHIIMD_01007	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NIPHIIMD_01008	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
NIPHIIMD_01009	0.0	-	-	-	M	-	-	-	probably involved in cell wall
NIPHIIMD_01010	3.25e-241	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_01011	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01012	8.18e-215	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01013	7.99e-196	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01014	2.54e-295	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
NIPHIIMD_01016	3.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NIPHIIMD_01017	3.32e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIPHIIMD_01018	1.58e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
NIPHIIMD_01019	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIPHIIMD_01020	1.28e-41	-	-	-	-	-	-	-	-
NIPHIIMD_01021	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NIPHIIMD_01022	4.15e-209	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIPHIIMD_01023	5.46e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
NIPHIIMD_01024	9.85e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NIPHIIMD_01025	2.43e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIPHIIMD_01026	5.37e-168	-	-	-	S	-	-	-	DUF218 domain
NIPHIIMD_01027	1.68e-165	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01028	1.73e-17	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
NIPHIIMD_01029	2.23e-95	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
NIPHIIMD_01030	5.87e-182	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
NIPHIIMD_01031	7.36e-79	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
NIPHIIMD_01032	4.51e-102	-	-	-	V	-	-	-	Abi-like protein
NIPHIIMD_01033	3.58e-16	-	-	-	-	-	-	-	-
NIPHIIMD_01034	2.56e-120	-	-	-	-	-	-	-	-
NIPHIIMD_01035	3.23e-112	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01036	3.43e-74	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NIPHIIMD_01037	3.57e-220	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIPHIIMD_01038	8.85e-129	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NIPHIIMD_01039	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
NIPHIIMD_01040	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NIPHIIMD_01041	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NIPHIIMD_01042	9.11e-216	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NIPHIIMD_01043	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIPHIIMD_01044	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIPHIIMD_01045	5.84e-239	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
NIPHIIMD_01046	7.75e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
NIPHIIMD_01047	1.02e-226	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
NIPHIIMD_01048	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIPHIIMD_01049	8.68e-207	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
NIPHIIMD_01050	9.28e-207	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
NIPHIIMD_01051	6.1e-207	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
NIPHIIMD_01052	6.26e-222	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01053	5.24e-187	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_01054	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIPHIIMD_01055	7.21e-187	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
NIPHIIMD_01056	1.09e-290	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NIPHIIMD_01057	5.33e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
NIPHIIMD_01058	1.22e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIPHIIMD_01060	5.48e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NIPHIIMD_01061	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NIPHIIMD_01062	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIPHIIMD_01063	1.06e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01064	2.9e-203	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01065	1.87e-307	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01066	3.13e-296	-	-	-	GK	-	-	-	ROK family
NIPHIIMD_01067	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NIPHIIMD_01068	9.44e-100	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIPHIIMD_01069	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
NIPHIIMD_01070	7.8e-195	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NIPHIIMD_01071	8.25e-142	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
NIPHIIMD_01072	2.72e-17	-	-	-	L	-	-	-	PFAM Integrase catalytic
NIPHIIMD_01073	2.03e-152	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_01074	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NIPHIIMD_01075	2.95e-153	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIPHIIMD_01076	3.31e-302	-	-	-	G	-	-	-	MFS/sugar transport protein
NIPHIIMD_01077	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
NIPHIIMD_01078	7.78e-133	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
NIPHIIMD_01079	4.63e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
NIPHIIMD_01080	1.98e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIPHIIMD_01082	2.23e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIPHIIMD_01083	1.69e-192	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_01084	5.1e-114	-	-	-	S	-	-	-	FMN_bind
NIPHIIMD_01085	2.25e-119	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01086	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NIPHIIMD_01087	4.06e-58	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NIPHIIMD_01088	1.23e-157	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NIPHIIMD_01089	1.37e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
NIPHIIMD_01090	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
NIPHIIMD_01091	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NIPHIIMD_01092	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIPHIIMD_01093	7.75e-130	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIPHIIMD_01094	2.25e-312	dinF	-	-	V	-	-	-	MatE
NIPHIIMD_01095	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
NIPHIIMD_01097	8.74e-50	-	-	-	L	-	-	-	Helix-turn-helix domain
NIPHIIMD_01098	1.24e-129	-	-	-	V	-	-	-	Abi-like protein
NIPHIIMD_01100	1.52e-98	-	-	-	-	-	-	-	-
NIPHIIMD_01101	1.59e-144	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01102	4.01e-74	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIPHIIMD_01104	2.21e-188	-	-	-	P	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01105	2.74e-209	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01106	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01107	5.93e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01108	5.65e-99	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01109	3.91e-60	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NIPHIIMD_01110	7.76e-27	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01111	1.34e-18	-	-	-	L	-	-	-	Transposase, Mutator family
NIPHIIMD_01113	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIPHIIMD_01114	3.28e-193	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
NIPHIIMD_01115	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
NIPHIIMD_01116	2.67e-113	-	-	-	-	-	-	-	-
NIPHIIMD_01117	8.93e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NIPHIIMD_01118	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NIPHIIMD_01119	8.48e-178	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIPHIIMD_01120	8.1e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NIPHIIMD_01121	1.25e-148	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NIPHIIMD_01122	3.63e-136	-	-	-	-	-	-	-	-
NIPHIIMD_01124	1.47e-46	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NIPHIIMD_01125	5.22e-17	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NIPHIIMD_01126	1.91e-50	-	-	-	L	-	-	-	Transposase, Mutator family
NIPHIIMD_01127	8.44e-32	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NIPHIIMD_01128	8.5e-104	-	-	-	M	-	-	-	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIPHIIMD_01129	7.95e-27	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	protein conserved in bacteria
NIPHIIMD_01130	1.38e-74	yccF	-	-	S	-	-	-	Inner membrane component domain
NIPHIIMD_01131	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NIPHIIMD_01132	5.45e-94	-	-	-	-	-	-	-	-
NIPHIIMD_01133	8.75e-43	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01134	1.95e-82	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01135	6.99e-39	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NIPHIIMD_01136	8.05e-20	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NIPHIIMD_01137	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIPHIIMD_01138	3.09e-249	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIPHIIMD_01139	4.85e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
NIPHIIMD_01140	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_01141	9.93e-147	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NIPHIIMD_01142	1.55e-254	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
NIPHIIMD_01143	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NIPHIIMD_01144	1.11e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIPHIIMD_01145	2.61e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NIPHIIMD_01146	0.0	-	-	-	L	-	-	-	PIF1-like helicase
NIPHIIMD_01147	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NIPHIIMD_01148	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NIPHIIMD_01149	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIPHIIMD_01150	3.02e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NIPHIIMD_01151	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIPHIIMD_01152	1.91e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIPHIIMD_01153	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIPHIIMD_01154	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIPHIIMD_01155	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIPHIIMD_01156	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIPHIIMD_01157	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NIPHIIMD_01158	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIPHIIMD_01159	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIPHIIMD_01160	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIPHIIMD_01161	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIPHIIMD_01162	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIPHIIMD_01163	3.93e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIPHIIMD_01164	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIPHIIMD_01165	1.86e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIPHIIMD_01166	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIPHIIMD_01167	5.07e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
NIPHIIMD_01168	5.12e-96	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NIPHIIMD_01169	5.9e-314	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIPHIIMD_01170	3e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIPHIIMD_01171	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIPHIIMD_01172	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NIPHIIMD_01173	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIPHIIMD_01174	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIPHIIMD_01175	6.43e-238	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPHIIMD_01176	1.21e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NIPHIIMD_01177	1.84e-214	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIPHIIMD_01179	3.63e-141	-	-	-	-	-	-	-	-
NIPHIIMD_01180	4.21e-243	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NIPHIIMD_01181	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIPHIIMD_01182	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIPHIIMD_01183	3.51e-241	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIPHIIMD_01184	1.01e-277	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
NIPHIIMD_01185	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIPHIIMD_01186	2.31e-140	-	-	-	-	-	-	-	-
NIPHIIMD_01187	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NIPHIIMD_01188	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIPHIIMD_01189	1.32e-279	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIPHIIMD_01190	2.56e-315	-	-	-	T	-	-	-	GHKL domain
NIPHIIMD_01191	1.46e-195	-	-	-	T	-	-	-	LytTr DNA-binding domain
NIPHIIMD_01192	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NIPHIIMD_01193	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NIPHIIMD_01194	3.44e-204	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NIPHIIMD_01195	1.21e-262	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NIPHIIMD_01196	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIPHIIMD_01198	1.68e-239	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NIPHIIMD_01199	1.86e-242	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NIPHIIMD_01200	0.0	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
NIPHIIMD_01201	2.78e-132	-	-	-	Q	-	-	-	Isochorismatase family
NIPHIIMD_01202	1.08e-273	-	-	-	S	-	-	-	Choline/ethanolamine kinase
NIPHIIMD_01203	0.0	-	-	-	E	ko:K16238	-	ko00000,ko02000	Amino acid permease
NIPHIIMD_01204	0.0	-	-	-	H	-	-	-	Aminotransferase class-III
NIPHIIMD_01205	7.14e-183	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
NIPHIIMD_01206	2.9e-157	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NIPHIIMD_01207	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
NIPHIIMD_01208	5.43e-197	pspC	-	-	KT	-	-	-	PspC domain
NIPHIIMD_01209	5.5e-121	-	-	-	-	-	-	-	-
NIPHIIMD_01210	6.13e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
NIPHIIMD_01211	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
NIPHIIMD_01212	2.04e-275	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NIPHIIMD_01214	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NIPHIIMD_01215	1.61e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_01216	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NIPHIIMD_01217	2.99e-125	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
NIPHIIMD_01218	2.06e-268	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NIPHIIMD_01219	2.86e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIPHIIMD_01220	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
NIPHIIMD_01221	1.74e-132	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NIPHIIMD_01222	1.06e-273	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIPHIIMD_01223	3.36e-55	-	-	-	-	-	-	-	-
NIPHIIMD_01224	9.39e-278	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NIPHIIMD_01225	6.95e-212	-	-	-	S	-	-	-	CHAP domain
NIPHIIMD_01226	2.31e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NIPHIIMD_01227	1.53e-242	-	-	-	T	-	-	-	Universal stress protein family
NIPHIIMD_01228	7.52e-95	-	-	-	O	-	-	-	OsmC-like protein
NIPHIIMD_01229	2.4e-232	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIPHIIMD_01230	2.83e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
NIPHIIMD_01231	1.79e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
NIPHIIMD_01233	3.01e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIPHIIMD_01234	6.21e-204	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIPHIIMD_01238	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
NIPHIIMD_01239	2.09e-213	-	-	-	-	-	-	-	-
NIPHIIMD_01240	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
NIPHIIMD_01241	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
NIPHIIMD_01242	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
NIPHIIMD_01243	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
NIPHIIMD_01244	5.75e-205	-	-	-	P	-	-	-	VTC domain
NIPHIIMD_01245	2.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
NIPHIIMD_01246	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
NIPHIIMD_01247	7.06e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NIPHIIMD_01248	1.56e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NIPHIIMD_01249	0.0	-	-	-	S	-	-	-	AI-2E family transporter
NIPHIIMD_01250	9.34e-294	-	-	-	M	-	-	-	Glycosyl transferase family 21
NIPHIIMD_01251	3.74e-294	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
NIPHIIMD_01252	1.89e-253	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIPHIIMD_01253	4.06e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NIPHIIMD_01255	9.79e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_01256	4.23e-305	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01257	1.46e-209	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01258	1.91e-203	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01259	5.66e-305	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NIPHIIMD_01260	9.3e-12	-	-	-	ET	ko:K02030,ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NIPHIIMD_01261	1.35e-23	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NIPHIIMD_01262	5.27e-134	odh	1.5.1.28	-	I	ko:K04940	-	ko00000,ko01000	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NIPHIIMD_01263	1.15e-93	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIPHIIMD_01264	8.69e-52	-	-	-	E	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01265	4.86e-36	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01266	4.76e-67	-	-	-	L	-	-	-	Transposase
NIPHIIMD_01267	1.92e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIPHIIMD_01269	7.33e-272	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
NIPHIIMD_01270	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIPHIIMD_01271	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIPHIIMD_01272	6.8e-162	-	-	-	-	-	-	-	-
NIPHIIMD_01273	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01274	2.15e-68	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_01276	2.21e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
NIPHIIMD_01277	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
NIPHIIMD_01278	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NIPHIIMD_01279	4.39e-214	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIPHIIMD_01280	7.35e-221	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIPHIIMD_01281	2.48e-255	rpfB	-	-	S	ko:K21688	-	ko00000	G5
NIPHIIMD_01283	9.07e-127	-	-	-	O	-	-	-	Thioredoxin
NIPHIIMD_01284	2.52e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01285	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NIPHIIMD_01286	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NIPHIIMD_01287	2.49e-167	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
NIPHIIMD_01288	5.22e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
NIPHIIMD_01289	1.91e-231	-	-	-	C	-	-	-	Aldo/keto reductase family
NIPHIIMD_01290	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NIPHIIMD_01292	2.51e-199	-	-	-	S	-	-	-	Glutamine amidotransferase domain
NIPHIIMD_01293	7.79e-193	-	-	-	T	ko:K06950	-	ko00000	HD domain
NIPHIIMD_01294	3.07e-240	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIPHIIMD_01295	4.62e-309	-	-	-	V	-	-	-	ABC transporter permease
NIPHIIMD_01296	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NIPHIIMD_01297	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
NIPHIIMD_01298	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NIPHIIMD_01300	1.21e-315	-	-	-	S	-	-	-	zinc finger
NIPHIIMD_01301	1.05e-97	-	-	-	S	-	-	-	Bacterial PH domain
NIPHIIMD_01302	2.94e-99	-	-	-	-	-	-	-	-
NIPHIIMD_01303	0.0	-	-	-	V	-	-	-	Domain of unknown function (DUF3427)
NIPHIIMD_01304	4.72e-134	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
NIPHIIMD_01305	2.03e-92	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NIPHIIMD_01306	1.68e-39	-	-	-	S	-	-	-	domain protein
NIPHIIMD_01307	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIPHIIMD_01308	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NIPHIIMD_01309	9.55e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIPHIIMD_01310	8.7e-85	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
NIPHIIMD_01311	6.41e-193	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
NIPHIIMD_01312	8.39e-196	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NIPHIIMD_01313	2.12e-224	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
NIPHIIMD_01314	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIPHIIMD_01315	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NIPHIIMD_01316	1.89e-139	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIPHIIMD_01317	6.59e-142	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
NIPHIIMD_01318	1.99e-109	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NIPHIIMD_01319	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NIPHIIMD_01321	5.88e-176	-	-	-	NU	ko:K02671	-	ko00000,ko02035,ko02044	Prokaryotic N-terminal methylation motif
NIPHIIMD_01322	1.55e-135	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
NIPHIIMD_01323	9.26e-93	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
NIPHIIMD_01324	2.22e-296	tapC	-	-	U	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
NIPHIIMD_01325	0.0	-	-	-	-	-	-	-	-
NIPHIIMD_01326	9e-194	pppA	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Bacterial Peptidase A24 N-terminal domain
NIPHIIMD_01327	5.34e-245	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
NIPHIIMD_01328	1.98e-211	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
NIPHIIMD_01329	3.3e-137	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
NIPHIIMD_01330	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
NIPHIIMD_01331	1.31e-310	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIPHIIMD_01332	4.66e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIPHIIMD_01333	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIPHIIMD_01334	9.14e-55	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NIPHIIMD_01335	2.23e-65	-	-	-	V	-	-	-	DivIVA protein
NIPHIIMD_01336	5.61e-121	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIPHIIMD_01337	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIPHIIMD_01338	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NIPHIIMD_01339	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIPHIIMD_01340	1.36e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIPHIIMD_01341	4.56e-142	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NIPHIIMD_01342	1.24e-161	-	-	-	-	-	-	-	-
NIPHIIMD_01343	1.46e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIPHIIMD_01344	2.38e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NIPHIIMD_01345	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NIPHIIMD_01346	1.18e-304	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NIPHIIMD_01347	1.66e-185	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NIPHIIMD_01348	5.22e-279	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NIPHIIMD_01349	3.86e-156	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_01350	1.44e-152	-	-	-	-	-	-	-	-
NIPHIIMD_01351	2.78e-251	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
NIPHIIMD_01352	4.61e-251	-	-	-	-	-	-	-	-
NIPHIIMD_01353	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
NIPHIIMD_01354	5.64e-146	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NIPHIIMD_01355	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIPHIIMD_01356	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NIPHIIMD_01357	3.34e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIPHIIMD_01358	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIPHIIMD_01359	8.85e-72	-	-	-	M	-	-	-	Lysin motif
NIPHIIMD_01360	2.49e-110	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIPHIIMD_01361	1.19e-276	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NIPHIIMD_01362	0.0	-	-	-	L	-	-	-	DNA helicase
NIPHIIMD_01363	5.51e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NIPHIIMD_01364	1.41e-242	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIPHIIMD_01365	7.27e-82	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIPHIIMD_01366	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
NIPHIIMD_01367	1.04e-191	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIPHIIMD_01368	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIPHIIMD_01369	1.38e-251	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIPHIIMD_01370	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIPHIIMD_01371	4.97e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
NIPHIIMD_01372	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIPHIIMD_01373	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NIPHIIMD_01374	3.24e-180	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
NIPHIIMD_01375	1.99e-316	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NIPHIIMD_01377	1.96e-276	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
NIPHIIMD_01378	1.16e-212	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NIPHIIMD_01379	6.36e-277	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NIPHIIMD_01380	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NIPHIIMD_01381	1.15e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01382	5.18e-255	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01383	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NIPHIIMD_01384	5.09e-124	-	-	-	F	-	-	-	NUDIX domain
NIPHIIMD_01385	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NIPHIIMD_01386	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NIPHIIMD_01387	1.92e-239	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
NIPHIIMD_01388	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIPHIIMD_01389	1.11e-126	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NIPHIIMD_01390	1.25e-49	-	-	-	-	-	-	-	-
NIPHIIMD_01391	4.34e-237	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NIPHIIMD_01392	1.88e-219	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NIPHIIMD_01393	8.17e-114	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIPHIIMD_01394	2.98e-220	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIPHIIMD_01398	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIPHIIMD_01399	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIPHIIMD_01400	1.87e-232	-	-	-	T	-	-	-	Forkhead associated domain
NIPHIIMD_01403	1.65e-134	-	-	-	K	-	-	-	MarR family
NIPHIIMD_01404	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NIPHIIMD_01405	1.66e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_01407	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
NIPHIIMD_01408	2.66e-30	-	-	-	G	-	-	-	alpha-galactosidase
NIPHIIMD_01410	2.43e-214	-	-	-	-	-	-	-	-
NIPHIIMD_01411	3.82e-156	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NIPHIIMD_01412	3.53e-129	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NIPHIIMD_01413	1.14e-40	-	-	-	S	-	-	-	Putative regulatory protein
NIPHIIMD_01414	4.31e-116	-	-	-	NO	-	-	-	SAF
NIPHIIMD_01415	2.8e-47	-	-	-	-	-	-	-	-
NIPHIIMD_01416	2.46e-33	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NIPHIIMD_01417	9.32e-306	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
NIPHIIMD_01418	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
NIPHIIMD_01419	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NIPHIIMD_01420	3.72e-31	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NIPHIIMD_01421	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NIPHIIMD_01422	1.68e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NIPHIIMD_01423	1.02e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
NIPHIIMD_01424	6.03e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIPHIIMD_01426	2.11e-250	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
NIPHIIMD_01427	1.56e-162	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_01429	6.95e-91	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NIPHIIMD_01430	1.09e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
NIPHIIMD_01431	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIPHIIMD_01432	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NIPHIIMD_01433	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
NIPHIIMD_01434	1.4e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NIPHIIMD_01435	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIPHIIMD_01436	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIPHIIMD_01437	1.35e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIPHIIMD_01438	1.46e-167	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01439	8.08e-182	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
NIPHIIMD_01440	5.2e-147	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIPHIIMD_01441	0.0	-	-	-	N	-	-	-	Glycosyl hydrolases family 43
NIPHIIMD_01442	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
NIPHIIMD_01443	5.93e-263	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
NIPHIIMD_01444	1.58e-187	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
NIPHIIMD_01445	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIPHIIMD_01446	1.66e-210	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NIPHIIMD_01447	2.91e-189	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIPHIIMD_01448	2.82e-105	-	-	-	-	-	-	-	-
NIPHIIMD_01449	4.65e-269	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIPHIIMD_01450	9.36e-105	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
NIPHIIMD_01452	1.1e-177	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NIPHIIMD_01455	6.96e-225	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
NIPHIIMD_01456	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIPHIIMD_01457	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NIPHIIMD_01458	3.05e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIPHIIMD_01459	3.97e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NIPHIIMD_01460	7.12e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NIPHIIMD_01461	3.76e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIPHIIMD_01462	1.37e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIPHIIMD_01463	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NIPHIIMD_01464	2.25e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NIPHIIMD_01465	3.02e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NIPHIIMD_01466	2.33e-85	-	-	-	-	-	-	-	-
NIPHIIMD_01467	2.05e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIPHIIMD_01468	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NIPHIIMD_01469	6.26e-259	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
NIPHIIMD_01470	3.48e-177	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
NIPHIIMD_01471	1.09e-276	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIPHIIMD_01472	2.5e-162	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NIPHIIMD_01473	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
NIPHIIMD_01474	4.66e-214	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NIPHIIMD_01475	6.27e-63	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NIPHIIMD_01476	1.1e-174	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NIPHIIMD_01477	0.0	-	-	-	M	-	-	-	Glycosyl transferase family 8
NIPHIIMD_01478	7.37e-317	-	-	-	-	-	-	-	-
NIPHIIMD_01479	1.2e-215	-	-	-	S	-	-	-	Acyltransferase family
NIPHIIMD_01480	3.12e-202	-	-	-	M	-	-	-	Glycosyl transferase family 2
NIPHIIMD_01481	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NIPHIIMD_01482	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
NIPHIIMD_01483	5.69e-123	-	-	-	-	-	-	-	-
NIPHIIMD_01484	1.61e-16	-	-	-	-	-	-	-	-
NIPHIIMD_01485	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
NIPHIIMD_01486	8.87e-76	-	-	-	-	-	-	-	-
NIPHIIMD_01488	3.16e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_01489	2.31e-115	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIPHIIMD_01490	2.1e-122	-	-	-	EG	-	-	-	EamA-like transporter family
NIPHIIMD_01491	2.98e-287	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NIPHIIMD_01494	2.31e-191	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01495	2.98e-254	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIPHIIMD_01497	3.7e-118	-	-	-	L	-	-	-	PFAM Integrase catalytic
NIPHIIMD_01499	4.01e-253	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIPHIIMD_01501	2.94e-242	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NIPHIIMD_01502	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NIPHIIMD_01503	6.45e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NIPHIIMD_01504	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NIPHIIMD_01505	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
NIPHIIMD_01506	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIPHIIMD_01509	2.14e-213	-	-	-	EG	-	-	-	EamA-like transporter family
NIPHIIMD_01510	4.53e-244	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
NIPHIIMD_01511	1.33e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NIPHIIMD_01512	3.13e-292	-	-	-	T	-	-	-	Histidine kinase
NIPHIIMD_01513	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
NIPHIIMD_01514	2.6e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
NIPHIIMD_01515	1.57e-108	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NIPHIIMD_01516	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NIPHIIMD_01517	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NIPHIIMD_01518	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NIPHIIMD_01519	1.75e-226	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NIPHIIMD_01520	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NIPHIIMD_01521	3.3e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
NIPHIIMD_01522	1.36e-266	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NIPHIIMD_01523	4.54e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NIPHIIMD_01524	2.28e-90	crgA	-	-	D	-	-	-	Involved in cell division
NIPHIIMD_01525	2.89e-309	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
NIPHIIMD_01526	1.44e-184	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
NIPHIIMD_01527	1.33e-47	-	-	-	-	-	-	-	-
NIPHIIMD_01528	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIPHIIMD_01529	1.1e-82	-	-	-	I	-	-	-	Sterol carrier protein
NIPHIIMD_01530	1.49e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
NIPHIIMD_01531	6.48e-263	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIPHIIMD_01532	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPHIIMD_01533	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NIPHIIMD_01534	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NIPHIIMD_01535	5e-231	-	-	-	-	-	-	-	-
NIPHIIMD_01536	2.88e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NIPHIIMD_01537	6.78e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NIPHIIMD_01538	1.15e-239	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NIPHIIMD_01539	3.41e-142	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
NIPHIIMD_01543	5.21e-96	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIPHIIMD_01544	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NIPHIIMD_01545	5.13e-106	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
NIPHIIMD_01546	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIPHIIMD_01547	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIPHIIMD_01548	1.01e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NIPHIIMD_01549	2.23e-298	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIPHIIMD_01550	1.88e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIPHIIMD_01551	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIPHIIMD_01552	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NIPHIIMD_01553	3.51e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIPHIIMD_01554	2.26e-244	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
NIPHIIMD_01555	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
NIPHIIMD_01556	4.45e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NIPHIIMD_01557	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NIPHIIMD_01558	1.49e-271	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NIPHIIMD_01559	4.02e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIPHIIMD_01560	5.61e-20	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
NIPHIIMD_01561	1.85e-156	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NIPHIIMD_01562	6.29e-17	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NIPHIIMD_01563	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NIPHIIMD_01564	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NIPHIIMD_01565	1.05e-303	-	-	-	M	-	-	-	Conserved repeat domain
NIPHIIMD_01566	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NIPHIIMD_01567	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
NIPHIIMD_01568	3.16e-125	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NIPHIIMD_01569	1.75e-99	-	-	-	-	-	-	-	-
NIPHIIMD_01570	4.77e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NIPHIIMD_01571	2.32e-94	-	-	-	-	-	-	-	-
NIPHIIMD_01572	8.53e-115	-	-	-	-	-	-	-	-
NIPHIIMD_01573	8.25e-225	-	-	-	S	ko:K21688	-	ko00000	G5
NIPHIIMD_01574	4.09e-80	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
NIPHIIMD_01575	1.95e-147	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
NIPHIIMD_01576	9.56e-208	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NIPHIIMD_01577	1.26e-266	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
NIPHIIMD_01578	1.66e-92	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NIPHIIMD_01579	1.07e-301	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
NIPHIIMD_01580	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
NIPHIIMD_01581	9.62e-247	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NIPHIIMD_01582	2.28e-136	-	-	-	J	-	-	-	TM2 domain
NIPHIIMD_01583	3.66e-275	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NIPHIIMD_01584	3.02e-170	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
NIPHIIMD_01585	0.0	pon1	-	-	M	-	-	-	Transglycosylase
NIPHIIMD_01586	1.45e-280	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NIPHIIMD_01587	1.41e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NIPHIIMD_01588	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NIPHIIMD_01589	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
NIPHIIMD_01590	1.45e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
NIPHIIMD_01591	2.88e-30	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
NIPHIIMD_01592	9.28e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NIPHIIMD_01593	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NIPHIIMD_01594	2.24e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIPHIIMD_01595	1.55e-233	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
NIPHIIMD_01596	1e-137	-	-	-	-	-	-	-	-
NIPHIIMD_01597	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPHIIMD_01598	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPHIIMD_01599	1.82e-129	-	-	-	T	-	-	-	Forkhead associated domain
NIPHIIMD_01600	1.4e-151	-	-	-	B	-	-	-	Belongs to the OprB family
NIPHIIMD_01601	1.21e-210	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NIPHIIMD_01602	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NIPHIIMD_01603	2.31e-282	-	-	-	S	-	-	-	Protein of unknown function DUF58
NIPHIIMD_01604	3.65e-308	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NIPHIIMD_01605	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
NIPHIIMD_01606	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NIPHIIMD_01607	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NIPHIIMD_01608	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
NIPHIIMD_01609	4.01e-314	-	-	-	G	-	-	-	Major Facilitator Superfamily
NIPHIIMD_01610	4.54e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIPHIIMD_01611	6.79e-52	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
NIPHIIMD_01612	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NIPHIIMD_01613	2.37e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIPHIIMD_01614	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIPHIIMD_01615	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
NIPHIIMD_01616	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIPHIIMD_01617	4.69e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIPHIIMD_01618	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NIPHIIMD_01619	2.44e-05	-	-	-	-	-	-	-	-
NIPHIIMD_01620	3.39e-294	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
NIPHIIMD_01621	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NIPHIIMD_01622	2.47e-136	-	-	-	-	-	-	-	-
NIPHIIMD_01623	1.59e-244	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NIPHIIMD_01624	2.11e-250	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NIPHIIMD_01625	3e-46	-	-	-	-	-	-	-	-
NIPHIIMD_01626	9.27e-219	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NIPHIIMD_01627	2.33e-82	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NIPHIIMD_01629	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NIPHIIMD_01630	2.06e-206	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01631	1.18e-223	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NIPHIIMD_01632	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NIPHIIMD_01633	1.67e-219	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NIPHIIMD_01634	3.66e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
NIPHIIMD_01635	3.13e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
NIPHIIMD_01636	5.58e-309	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIPHIIMD_01637	2.14e-98	-	-	-	-	-	-	-	-
NIPHIIMD_01638	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NIPHIIMD_01639	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIPHIIMD_01640	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NIPHIIMD_01641	6.65e-152	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
NIPHIIMD_01642	4.7e-267	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NIPHIIMD_01643	4.13e-294	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIPHIIMD_01644	1.48e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NIPHIIMD_01645	1.72e-242	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_01646	4.04e-315	-	-	-	T	-	-	-	Histidine kinase
NIPHIIMD_01647	3.27e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NIPHIIMD_01648	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NIPHIIMD_01649	8.7e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NIPHIIMD_01650	3.12e-310	-	-	-	T	-	-	-	Histidine kinase
NIPHIIMD_01651	5.25e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NIPHIIMD_01652	4.11e-170	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NIPHIIMD_01653	6.83e-228	-	-	-	EG	-	-	-	EamA-like transporter family
NIPHIIMD_01654	6.96e-201	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NIPHIIMD_01655	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NIPHIIMD_01656	5.81e-249	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIPHIIMD_01658	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
NIPHIIMD_01659	2.7e-161	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIPHIIMD_01660	7.04e-127	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NIPHIIMD_01661	3.83e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIPHIIMD_01662	7.07e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
NIPHIIMD_01663	4.97e-271	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIPHIIMD_01664	1.56e-160	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NIPHIIMD_01665	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIPHIIMD_01666	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIPHIIMD_01667	3.23e-247	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIPHIIMD_01668	2.71e-130	-	-	-	-	-	-	-	-
NIPHIIMD_01669	3.04e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NIPHIIMD_01670	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
NIPHIIMD_01671	1.89e-253	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIPHIIMD_01672	2.58e-152	-	-	-	-	-	-	-	-
NIPHIIMD_01673	3.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIPHIIMD_01674	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NIPHIIMD_01675	1.04e-287	-	-	-	G	-	-	-	Major Facilitator Superfamily
NIPHIIMD_01676	3.27e-311	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
NIPHIIMD_01677	7.86e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NIPHIIMD_01678	6.21e-43	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NIPHIIMD_01679	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NIPHIIMD_01680	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NIPHIIMD_01682	2.14e-205	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01683	7.58e-217	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01684	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01685	5.89e-262	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NIPHIIMD_01686	1.09e-249	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NIPHIIMD_01687	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NIPHIIMD_01688	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
NIPHIIMD_01689	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
NIPHIIMD_01690	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIPHIIMD_01691	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIPHIIMD_01692	6.2e-148	-	-	-	-	-	-	-	-
NIPHIIMD_01693	5.73e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIPHIIMD_01694	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NIPHIIMD_01695	7.1e-175	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NIPHIIMD_01696	3.18e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIPHIIMD_01697	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
NIPHIIMD_01698	6.4e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_01699	7.61e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NIPHIIMD_01700	1.19e-277	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
NIPHIIMD_01701	6.79e-73	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
NIPHIIMD_01702	1.8e-79	-	-	-	U	-	-	-	TadE-like protein
NIPHIIMD_01703	3.15e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
NIPHIIMD_01704	3.29e-116	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
NIPHIIMD_01705	1.38e-158	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
NIPHIIMD_01706	2.42e-236	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
NIPHIIMD_01707	6.13e-182	-	-	-	D	-	-	-	bacterial-type flagellum organization
NIPHIIMD_01709	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIPHIIMD_01710	4.39e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
NIPHIIMD_01711	8.12e-134	-	-	-	-	-	-	-	-
NIPHIIMD_01712	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIPHIIMD_01713	3.97e-264	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NIPHIIMD_01714	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
NIPHIIMD_01715	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
NIPHIIMD_01716	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
NIPHIIMD_01717	1.61e-185	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01718	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NIPHIIMD_01720	4.39e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NIPHIIMD_01721	1.31e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
NIPHIIMD_01722	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
NIPHIIMD_01723	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
NIPHIIMD_01724	4.83e-177	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NIPHIIMD_01725	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
NIPHIIMD_01726	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NIPHIIMD_01727	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
NIPHIIMD_01728	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
NIPHIIMD_01729	1.45e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NIPHIIMD_01730	1.23e-252	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIPHIIMD_01731	1.1e-148	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIPHIIMD_01732	1.37e-249	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NIPHIIMD_01733	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NIPHIIMD_01735	3.55e-284	-	-	-	M	-	-	-	cell wall binding repeat
NIPHIIMD_01736	2.38e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NIPHIIMD_01737	8.57e-289	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NIPHIIMD_01739	1.89e-90	-	-	-	K	-	-	-	MerR, DNA binding
NIPHIIMD_01740	1.24e-156	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIPHIIMD_01741	2.31e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NIPHIIMD_01742	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIPHIIMD_01743	1.04e-309	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01744	1.83e-295	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
NIPHIIMD_01747	7.15e-232	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
NIPHIIMD_01748	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NIPHIIMD_01749	3.37e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIPHIIMD_01750	1.4e-158	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NIPHIIMD_01751	2.21e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIPHIIMD_01752	1.13e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NIPHIIMD_01753	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
NIPHIIMD_01754	3.73e-212	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NIPHIIMD_01755	4.11e-294	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NIPHIIMD_01756	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
NIPHIIMD_01757	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NIPHIIMD_01758	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NIPHIIMD_01759	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIPHIIMD_01760	3.06e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIPHIIMD_01761	1.64e-296	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NIPHIIMD_01763	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIPHIIMD_01764	9.08e-168	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NIPHIIMD_01765	1.83e-124	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIPHIIMD_01766	2.38e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIPHIIMD_01767	4.85e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NIPHIIMD_01768	0.0	-	-	-	-	-	-	-	-
NIPHIIMD_01769	1.78e-206	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NIPHIIMD_01770	9.8e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NIPHIIMD_01771	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NIPHIIMD_01772	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NIPHIIMD_01773	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
NIPHIIMD_01774	1.77e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIPHIIMD_01775	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NIPHIIMD_01777	1.89e-151	-	-	-	-	-	-	-	-
NIPHIIMD_01778	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIPHIIMD_01779	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NIPHIIMD_01780	8.51e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NIPHIIMD_01781	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NIPHIIMD_01782	1.53e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
NIPHIIMD_01783	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
NIPHIIMD_01784	5.45e-233	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NIPHIIMD_01785	7.53e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIPHIIMD_01786	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIPHIIMD_01787	7.66e-147	-	-	-	D	-	-	-	nuclear chromosome segregation
NIPHIIMD_01788	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NIPHIIMD_01789	2.1e-268	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIPHIIMD_01790	1.44e-281	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIPHIIMD_01791	1.22e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIPHIIMD_01792	2.91e-280	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NIPHIIMD_01793	2.31e-166	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NIPHIIMD_01794	5.23e-257	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
NIPHIIMD_01795	2.6e-209	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NIPHIIMD_01796	1.92e-218	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NIPHIIMD_01797	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIPHIIMD_01798	9.44e-186	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NIPHIIMD_01799	2.51e-30	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family