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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HAKMLPPD_00001	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HAKMLPPD_00002	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HAKMLPPD_00003	3.13e-211	-	-	-	O	-	-	-	Thioredoxin
HAKMLPPD_00005	5.02e-251	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HAKMLPPD_00006	1.99e-209	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAKMLPPD_00007	1.03e-212	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAKMLPPD_00008	8.42e-142	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HAKMLPPD_00009	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HAKMLPPD_00010	6.34e-156	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HAKMLPPD_00011	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HAKMLPPD_00012	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HAKMLPPD_00013	0.0	-	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HAKMLPPD_00014	1.71e-16	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HAKMLPPD_00015	7.24e-154	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HAKMLPPD_00017	1.6e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HAKMLPPD_00018	3.22e-94	-	-	-	K	-	-	-	FCD
HAKMLPPD_00019	1.37e-153	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HAKMLPPD_00020	0.0	-	-	-	IQ	ko:K06978	-	ko00000	Peptidase S15
HAKMLPPD_00021	5.36e-209	-	-	-	E	-	-	-	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAKMLPPD_00022	1.36e-147	-	-	-	U	ko:K02053,ko:K11070,ko:K11074	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00023	4.77e-166	-	-	-	U	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00024	1.03e-204	potD	-	-	E	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Required for the activity of the bacterial periplasmic transport system of putrescine
HAKMLPPD_00025	5.1e-186	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HAKMLPPD_00026	9.21e-135	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAKMLPPD_00027	6.27e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAKMLPPD_00028	4.98e-270	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAKMLPPD_00029	3.04e-221	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HAKMLPPD_00030	7.13e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HAKMLPPD_00031	2.6e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HAKMLPPD_00032	2.34e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HAKMLPPD_00033	4.37e-58	-	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HAKMLPPD_00034	1.39e-57	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HAKMLPPD_00035	2.68e-19	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HAKMLPPD_00036	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAKMLPPD_00037	1.27e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAKMLPPD_00038	5.03e-295	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAKMLPPD_00039	2.04e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HAKMLPPD_00040	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAKMLPPD_00041	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAKMLPPD_00042	4.91e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HAKMLPPD_00043	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HAKMLPPD_00044	7.4e-96	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAKMLPPD_00048	1.04e-127	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HAKMLPPD_00049	1.4e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HAKMLPPD_00050	1.78e-301	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HAKMLPPD_00051	4.27e-156	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HAKMLPPD_00052	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAKMLPPD_00053	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HAKMLPPD_00054	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAKMLPPD_00055	2.64e-262	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAKMLPPD_00056	2.05e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HAKMLPPD_00057	1.1e-82	-	-	-	I	-	-	-	Sterol carrier protein
HAKMLPPD_00058	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAKMLPPD_00059	8.12e-45	-	-	-	-	-	-	-	-
HAKMLPPD_00060	3.54e-185	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HAKMLPPD_00061	1.6e-291	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HAKMLPPD_00062	2.65e-89	crgA	-	-	D	-	-	-	Involved in cell division
HAKMLPPD_00063	1.85e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HAKMLPPD_00064	1.36e-266	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAKMLPPD_00065	3.7e-151	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HAKMLPPD_00066	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HAKMLPPD_00067	4.29e-227	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HAKMLPPD_00068	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HAKMLPPD_00069	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HAKMLPPD_00070	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HAKMLPPD_00071	1.54e-99	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HAKMLPPD_00072	7.44e-168	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HAKMLPPD_00073	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HAKMLPPD_00074	2.2e-292	-	-	-	T	-	-	-	Histidine kinase
HAKMLPPD_00075	6.6e-147	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_00076	3.19e-244	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HAKMLPPD_00077	3.95e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HAKMLPPD_00078	5.95e-111	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HAKMLPPD_00079	1.51e-58	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HAKMLPPD_00081	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAKMLPPD_00082	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HAKMLPPD_00083	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HAKMLPPD_00084	9.16e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HAKMLPPD_00085	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HAKMLPPD_00086	1.33e-254	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HAKMLPPD_00088	3.46e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAKMLPPD_00089	2.31e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HAKMLPPD_00090	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HAKMLPPD_00091	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HAKMLPPD_00092	6.83e-259	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HAKMLPPD_00093	2.89e-310	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAKMLPPD_00094	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HAKMLPPD_00095	1.28e-109	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAKMLPPD_00096	4.34e-66	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAKMLPPD_00097	1.9e-256	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAKMLPPD_00098	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HAKMLPPD_00099	1.54e-122	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HAKMLPPD_00100	2.02e-312	-	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HAKMLPPD_00101	5.88e-280	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_00102	1.27e-203	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00103	1.31e-186	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00104	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HAKMLPPD_00105	3.01e-309	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HAKMLPPD_00106	1.19e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAKMLPPD_00107	2.91e-257	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAKMLPPD_00108	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HAKMLPPD_00109	7.77e-195	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAKMLPPD_00110	1.24e-192	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HAKMLPPD_00111	0.0	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HAKMLPPD_00112	8.49e-279	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HAKMLPPD_00113	1.36e-227	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00114	1.97e-183	-	-	-	U	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00115	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
HAKMLPPD_00116	7.12e-232	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_00117	1.52e-107	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HAKMLPPD_00118	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HAKMLPPD_00119	8.32e-131	-	-	-	-	-	-	-	-
HAKMLPPD_00120	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HAKMLPPD_00121	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAKMLPPD_00122	5.46e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00123	3.47e-233	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAKMLPPD_00124	5.19e-134	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HAKMLPPD_00125	3.48e-227	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HAKMLPPD_00126	2.35e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00127	0.0	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HAKMLPPD_00128	1.32e-07	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HAKMLPPD_00129	2.77e-234	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAKMLPPD_00130	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HAKMLPPD_00131	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HAKMLPPD_00132	5.1e-87	-	-	-	-	-	-	-	-
HAKMLPPD_00133	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HAKMLPPD_00134	1.79e-214	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HAKMLPPD_00135	4.3e-168	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HAKMLPPD_00136	5.22e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HAKMLPPD_00137	3.43e-225	-	-	-	C	-	-	-	Aldo/keto reductase family
HAKMLPPD_00138	3.21e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAKMLPPD_00139	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_00140	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HAKMLPPD_00141	3.55e-150	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAKMLPPD_00142	2.54e-303	-	-	-	G	-	-	-	MFS/sugar transport protein
HAKMLPPD_00143	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HAKMLPPD_00144	7.78e-133	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HAKMLPPD_00145	6.58e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HAKMLPPD_00146	4.66e-285	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAKMLPPD_00148	1.57e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAKMLPPD_00149	8.38e-193	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_00150	3.44e-112	-	-	-	S	-	-	-	FMN_bind
HAKMLPPD_00152	1.66e-121	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00153	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HAKMLPPD_00154	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HAKMLPPD_00155	7.04e-288	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HAKMLPPD_00156	2.38e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HAKMLPPD_00157	8.06e-290	-	-	-	M	-	-	-	cell wall binding repeat
HAKMLPPD_00159	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HAKMLPPD_00160	1.37e-249	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HAKMLPPD_00161	3.13e-148	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_00162	1.23e-252	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAKMLPPD_00163	1.45e-302	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HAKMLPPD_00164	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HAKMLPPD_00165	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HAKMLPPD_00166	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HAKMLPPD_00167	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HAKMLPPD_00168	2.91e-178	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HAKMLPPD_00169	4.06e-42	-	-	-	S	-	-	-	granule-associated protein
HAKMLPPD_00170	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HAKMLPPD_00171	1.31e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HAKMLPPD_00172	4.39e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_00174	5.95e-214	-	-	-	P	ko:K02025,ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00175	3.39e-187	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00176	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HAKMLPPD_00177	0.0	-	3.2.1.187	GH121	DG	ko:K18206	-	ko00000,ko01000	Bacterial Ig-like domain (group 4)
HAKMLPPD_00178	0.0	-	-	-	G	-	-	-	Bacterial Ig-like domain (group 4)
HAKMLPPD_00179	3.26e-263	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HAKMLPPD_00180	1.64e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAKMLPPD_00181	7.54e-133	-	-	-	-	-	-	-	-
HAKMLPPD_00182	1.08e-287	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HAKMLPPD_00183	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAKMLPPD_00185	1.24e-181	-	-	-	D	-	-	-	bacterial-type flagellum organization
HAKMLPPD_00186	1.1e-232	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HAKMLPPD_00187	3.54e-161	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HAKMLPPD_00188	1.4e-117	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HAKMLPPD_00189	3.15e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HAKMLPPD_00190	1.8e-79	-	-	-	U	-	-	-	TadE-like protein
HAKMLPPD_00191	5.58e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HAKMLPPD_00192	9.99e-273	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HAKMLPPD_00193	5.35e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAKMLPPD_00194	1.57e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_00195	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HAKMLPPD_00196	6.41e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAKMLPPD_00197	1.18e-173	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HAKMLPPD_00198	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HAKMLPPD_00199	5.73e-264	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAKMLPPD_00200	1.28e-89	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HAKMLPPD_00201	0.0	-	-	-	G	-	-	-	lipolytic protein G-D-S-L family
HAKMLPPD_00202	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00203	1.33e-295	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_00204	2.63e-198	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00205	1.82e-181	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00206	4.22e-201	-	-	-	K	-	-	-	Periplasmic binding protein domain
HAKMLPPD_00207	4.35e-59	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HAKMLPPD_00208	5.84e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HAKMLPPD_00210	1.4e-48	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_00211	1.34e-53	-	-	-	-	-	-	-	-
HAKMLPPD_00212	2.53e-147	-	-	-	-	-	-	-	-
HAKMLPPD_00213	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAKMLPPD_00214	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAKMLPPD_00215	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
HAKMLPPD_00216	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	C-terminal of Glycosyl hydrolases family 43
HAKMLPPD_00217	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAKMLPPD_00218	1.09e-249	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_00219	1.24e-263	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAKMLPPD_00220	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_00221	1.98e-213	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00222	5.47e-211	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00223	4.6e-234	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HAKMLPPD_00224	1.11e-130	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HAKMLPPD_00225	2.13e-68	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HAKMLPPD_00226	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HAKMLPPD_00227	1.1e-276	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
HAKMLPPD_00228	8.01e-301	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HAKMLPPD_00229	8.7e-243	-	-	-	I	-	-	-	PAP2 superfamily
HAKMLPPD_00230	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAKMLPPD_00231	6.95e-135	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAKMLPPD_00232	5.75e-249	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HAKMLPPD_00233	2.06e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAKMLPPD_00234	6.22e-52	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HAKMLPPD_00235	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAKMLPPD_00236	5.02e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HAKMLPPD_00237	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HAKMLPPD_00238	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HAKMLPPD_00239	1.58e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HAKMLPPD_00240	1.06e-123	-	-	-	S	-	-	-	GtrA-like protein
HAKMLPPD_00241	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAKMLPPD_00242	2.7e-153	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HAKMLPPD_00243	1.86e-242	-	-	-	-	-	-	-	-
HAKMLPPD_00244	6.09e-188	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HAKMLPPD_00245	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAKMLPPD_00248	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAKMLPPD_00249	5.46e-180	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HAKMLPPD_00250	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAKMLPPD_00251	2.1e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAKMLPPD_00252	6.6e-259	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HAKMLPPD_00253	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAKMLPPD_00254	6.04e-226	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HAKMLPPD_00255	3.74e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HAKMLPPD_00256	1.23e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HAKMLPPD_00257	7.21e-225	-	-	-	S	-	-	-	CAAX protease self-immunity
HAKMLPPD_00258	1.96e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
HAKMLPPD_00259	5.84e-293	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00260	2.44e-286	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00261	1.29e-158	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_00262	1.08e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00263	4.75e-211	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
HAKMLPPD_00264	3.75e-288	gnuT	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HAKMLPPD_00265	1.19e-102	gntK	2.7.1.12	-	F	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Shikimate kinase
HAKMLPPD_00266	1.01e-165	gntR	-	-	K	-	-	-	FCD
HAKMLPPD_00267	1.17e-304	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HAKMLPPD_00268	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00269	1.82e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HAKMLPPD_00270	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HAKMLPPD_00271	1.25e-135	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HAKMLPPD_00272	1.8e-192	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HAKMLPPD_00273	1.81e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAKMLPPD_00274	5.05e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HAKMLPPD_00275	7.94e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HAKMLPPD_00276	1.5e-233	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HAKMLPPD_00277	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAKMLPPD_00278	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAKMLPPD_00279	4.66e-193	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HAKMLPPD_00280	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HAKMLPPD_00281	5.66e-124	-	-	-	-	-	-	-	-
HAKMLPPD_00282	1.54e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HAKMLPPD_00283	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HAKMLPPD_00284	2.43e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAKMLPPD_00285	8.1e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HAKMLPPD_00286	1.52e-149	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HAKMLPPD_00287	2.98e-171	-	-	-	-	-	-	-	-
HAKMLPPD_00288	8.23e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAKMLPPD_00289	2.92e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HAKMLPPD_00290	6.86e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HAKMLPPD_00291	6.07e-102	-	-	-	K	-	-	-	MerR, DNA binding
HAKMLPPD_00292	3.4e-154	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAKMLPPD_00293	1.9e-179	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAKMLPPD_00294	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAKMLPPD_00295	3.68e-294	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00296	1.17e-289	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00299	1.83e-227	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HAKMLPPD_00300	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HAKMLPPD_00301	2.89e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAKMLPPD_00302	2.22e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAKMLPPD_00303	1.02e-145	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAKMLPPD_00304	4.62e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00305	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HAKMLPPD_00306	8.77e-211	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HAKMLPPD_00307	5.6e-292	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HAKMLPPD_00308	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HAKMLPPD_00309	1.19e-61	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HAKMLPPD_00310	3.53e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HAKMLPPD_00311	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAKMLPPD_00312	4.16e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAKMLPPD_00313	9.46e-296	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HAKMLPPD_00315	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAKMLPPD_00316	1.42e-172	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HAKMLPPD_00317	2.91e-121	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAKMLPPD_00318	6.83e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAKMLPPD_00319	2.31e-183	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HAKMLPPD_00320	0.0	-	-	-	-	-	-	-	-
HAKMLPPD_00321	6.51e-208	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HAKMLPPD_00322	5.42e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HAKMLPPD_00323	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HAKMLPPD_00324	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HAKMLPPD_00325	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HAKMLPPD_00326	1.77e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAKMLPPD_00327	0.0	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HAKMLPPD_00329	4.63e-152	-	-	-	-	-	-	-	-
HAKMLPPD_00330	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAKMLPPD_00331	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAKMLPPD_00332	2.09e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HAKMLPPD_00333	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HAKMLPPD_00334	3.52e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HAKMLPPD_00335	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HAKMLPPD_00336	1.28e-231	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HAKMLPPD_00337	1.85e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAKMLPPD_00338	8.36e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAKMLPPD_00339	8.72e-146	-	-	-	D	-	-	-	nuclear chromosome segregation
HAKMLPPD_00340	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HAKMLPPD_00341	2.1e-268	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAKMLPPD_00342	6.13e-283	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAKMLPPD_00343	8.96e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAKMLPPD_00344	1.27e-277	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HAKMLPPD_00345	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HAKMLPPD_00346	2.9e-254	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HAKMLPPD_00347	2.6e-209	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HAKMLPPD_00348	1.92e-218	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HAKMLPPD_00349	6.41e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAKMLPPD_00350	3.84e-185	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HAKMLPPD_00351	1.06e-311	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HAKMLPPD_00352	5.91e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAKMLPPD_00353	5.66e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAKMLPPD_00354	9.59e-227	-	-	-	T	-	-	-	Forkhead associated domain
HAKMLPPD_00355	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HAKMLPPD_00356	2.9e-49	-	-	-	-	-	-	-	-
HAKMLPPD_00357	9.12e-118	-	-	-	NO	-	-	-	SAF
HAKMLPPD_00358	2.78e-41	-	-	-	S	-	-	-	Putative regulatory protein
HAKMLPPD_00359	2.49e-129	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HAKMLPPD_00360	4.85e-159	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAKMLPPD_00361	6.92e-221	-	-	-	-	-	-	-	-
HAKMLPPD_00362	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAKMLPPD_00366	7.79e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HAKMLPPD_00367	5.77e-268	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HAKMLPPD_00368	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HAKMLPPD_00369	2.61e-78	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HAKMLPPD_00370	1.38e-272	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HAKMLPPD_00371	1.26e-41	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HAKMLPPD_00372	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00373	1.13e-298	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HAKMLPPD_00374	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HAKMLPPD_00375	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HAKMLPPD_00377	1.07e-283	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAKMLPPD_00378	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HAKMLPPD_00379	1.35e-237	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAKMLPPD_00380	4.67e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HAKMLPPD_00381	2.02e-156	-	-	-	-	-	-	-	-
HAKMLPPD_00382	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HAKMLPPD_00383	2.26e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAKMLPPD_00384	1.21e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HAKMLPPD_00385	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HAKMLPPD_00386	5.14e-100	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAKMLPPD_00387	1.93e-273	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HAKMLPPD_00388	1.23e-304	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAKMLPPD_00389	5.19e-251	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HAKMLPPD_00390	8.4e-234	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAKMLPPD_00391	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HAKMLPPD_00392	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HAKMLPPD_00393	1.64e-151	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAKMLPPD_00394	1.82e-152	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HAKMLPPD_00395	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAKMLPPD_00396	2.71e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAKMLPPD_00397	3.44e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAKMLPPD_00398	5.42e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAKMLPPD_00399	2.74e-147	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAKMLPPD_00400	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAKMLPPD_00401	1.37e-50	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HAKMLPPD_00402	5.52e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAKMLPPD_00403	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAKMLPPD_00404	1.81e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAKMLPPD_00405	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAKMLPPD_00406	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAKMLPPD_00407	3.93e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAKMLPPD_00408	5.66e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAKMLPPD_00409	1.86e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAKMLPPD_00410	5.14e-130	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAKMLPPD_00411	1.24e-35	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HAKMLPPD_00412	1.79e-96	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HAKMLPPD_00413	1.97e-312	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAKMLPPD_00414	6.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAKMLPPD_00415	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAKMLPPD_00416	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HAKMLPPD_00417	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAKMLPPD_00418	1.48e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAKMLPPD_00419	7.5e-237	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAKMLPPD_00420	8.97e-89	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HAKMLPPD_00421	6.16e-213	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAKMLPPD_00423	1.27e-141	-	-	-	-	-	-	-	-
HAKMLPPD_00424	1.41e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HAKMLPPD_00425	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAKMLPPD_00426	1.9e-98	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAKMLPPD_00427	1e-240	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAKMLPPD_00428	9.71e-276	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HAKMLPPD_00429	1.27e-154	-	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAKMLPPD_00430	2.92e-182	-	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00431	6.96e-160	-	-	-	ET	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
HAKMLPPD_00432	3.51e-90	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HAKMLPPD_00433	1.56e-312	-	-	-	F	-	-	-	Amidohydrolase family
HAKMLPPD_00434	4.58e-288	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
HAKMLPPD_00435	8.81e-317	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAKMLPPD_00436	9.41e-140	-	-	-	-	-	-	-	-
HAKMLPPD_00437	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HAKMLPPD_00438	3.43e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAKMLPPD_00439	3.25e-280	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAKMLPPD_00440	0.0	-	-	-	T	-	-	-	GHKL domain
HAKMLPPD_00441	2.94e-195	-	-	-	T	-	-	-	LytTr DNA-binding domain
HAKMLPPD_00443	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HAKMLPPD_00444	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HAKMLPPD_00445	3.44e-204	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAKMLPPD_00446	8.45e-264	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HAKMLPPD_00447	4.35e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAKMLPPD_00450	8.78e-242	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HAKMLPPD_00451	1.86e-242	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HAKMLPPD_00452	0.0	-	-	-	U	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
HAKMLPPD_00453	3.38e-133	-	-	-	Q	-	-	-	Isochorismatase family
HAKMLPPD_00454	1.08e-273	-	-	-	S	-	-	-	Choline/ethanolamine kinase
HAKMLPPD_00455	0.0	-	-	-	E	ko:K16238	-	ko00000,ko02000	Amino acid permease
HAKMLPPD_00456	0.0	-	-	-	H	-	-	-	Aminotransferase class-III
HAKMLPPD_00457	1.18e-181	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
HAKMLPPD_00458	2.9e-157	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_00459	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
HAKMLPPD_00460	1.04e-211	pspC	-	-	KT	-	-	-	PspC domain
HAKMLPPD_00461	2.26e-129	-	-	-	-	-	-	-	-
HAKMLPPD_00462	1.06e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HAKMLPPD_00463	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HAKMLPPD_00464	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HAKMLPPD_00465	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HAKMLPPD_00466	2.02e-175	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_00467	1.16e-46	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HAKMLPPD_00468	6.68e-71	-	-	-	S	-	-	-	Hypothetical bacterial integral membrane protein (Trep_Strep)
HAKMLPPD_00469	2.04e-275	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HAKMLPPD_00471	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HAKMLPPD_00472	2.53e-265	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HAKMLPPD_00473	2.86e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAKMLPPD_00474	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HAKMLPPD_00475	4.25e-149	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HAKMLPPD_00476	2.21e-243	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAKMLPPD_00477	1.6e-53	-	-	-	-	-	-	-	-
HAKMLPPD_00478	2.21e-276	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAKMLPPD_00479	2.65e-200	-	-	-	S	-	-	-	CHAP domain
HAKMLPPD_00480	3.42e-133	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HAKMLPPD_00481	3.51e-240	-	-	-	T	-	-	-	Universal stress protein family
HAKMLPPD_00482	6.19e-94	-	-	-	O	-	-	-	OsmC-like protein
HAKMLPPD_00483	6.89e-232	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAKMLPPD_00484	9.87e-166	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HAKMLPPD_00485	8.88e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HAKMLPPD_00487	3.01e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAKMLPPD_00488	1.08e-216	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAKMLPPD_00492	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HAKMLPPD_00493	8.73e-206	-	-	-	-	-	-	-	-
HAKMLPPD_00494	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HAKMLPPD_00495	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HAKMLPPD_00496	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HAKMLPPD_00497	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HAKMLPPD_00498	5.3e-201	-	-	-	P	-	-	-	VTC domain
HAKMLPPD_00499	4.21e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HAKMLPPD_00500	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HAKMLPPD_00501	1.42e-269	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HAKMLPPD_00502	3.15e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAKMLPPD_00503	3.76e-312	-	-	-	S	-	-	-	AI-2E family transporter
HAKMLPPD_00504	1.09e-292	-	-	-	M	-	-	-	Glycosyl transferase family 21
HAKMLPPD_00505	5e-299	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HAKMLPPD_00506	3.26e-254	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAKMLPPD_00507	1.72e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HAKMLPPD_00508	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAKMLPPD_00509	2.51e-150	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HAKMLPPD_00510	1.76e-199	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAKMLPPD_00511	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAKMLPPD_00512	1.94e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HAKMLPPD_00513	6.48e-211	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HAKMLPPD_00514	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HAKMLPPD_00515	2.22e-230	-	-	-	V	-	-	-	Beta-lactamase
HAKMLPPD_00516	3.03e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAKMLPPD_00517	3.69e-20	-	3.2.1.156	GH8	G	ko:K15531	-	ko00000,ko01000	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HAKMLPPD_00518	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HAKMLPPD_00519	8.49e-12	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HAKMLPPD_00520	5.55e-268	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HAKMLPPD_00522	8.24e-217	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
HAKMLPPD_00523	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HAKMLPPD_00524	2.18e-288	xylR	-	-	GK	-	-	-	ROK family
HAKMLPPD_00525	7.95e-114	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HAKMLPPD_00526	3.35e-29	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HAKMLPPD_00527	2.76e-115	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HAKMLPPD_00528	6.09e-139	-	-	-	S	ko:K07149	-	ko00000	Membrane
HAKMLPPD_00529	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HAKMLPPD_00530	1.41e-308	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
HAKMLPPD_00531	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HAKMLPPD_00532	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HAKMLPPD_00533	9.5e-239	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HAKMLPPD_00534	7.95e-294	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HAKMLPPD_00535	8.6e-230	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00536	6.92e-204	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00537	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HAKMLPPD_00538	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HAKMLPPD_00539	4.05e-143	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HAKMLPPD_00540	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HAKMLPPD_00541	2.09e-286	xylR	-	-	GK	-	-	-	ROK family
HAKMLPPD_00543	2.63e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HAKMLPPD_00544	8.21e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAKMLPPD_00545	3.12e-221	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAKMLPPD_00546	6.78e-279	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HAKMLPPD_00547	8.89e-199	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAKMLPPD_00548	1.71e-246	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAKMLPPD_00549	6.89e-192	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HAKMLPPD_00550	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00551	3.87e-144	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HAKMLPPD_00552	1.27e-253	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HAKMLPPD_00553	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAKMLPPD_00554	4.51e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HAKMLPPD_00555	6.73e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAKMLPPD_00556	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HAKMLPPD_00557	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAKMLPPD_00558	1.31e-120	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HAKMLPPD_00559	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HAKMLPPD_00560	5.71e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HAKMLPPD_00561	9.67e-317	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HAKMLPPD_00562	4.32e-214	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HAKMLPPD_00563	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAKMLPPD_00564	2.95e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAKMLPPD_00565	4.55e-236	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HAKMLPPD_00566	3.16e-205	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HAKMLPPD_00567	7.31e-219	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HAKMLPPD_00568	5e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAKMLPPD_00569	3.53e-206	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HAKMLPPD_00570	1.57e-38	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HAKMLPPD_00571	9.68e-204	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HAKMLPPD_00572	2.24e-215	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00573	2.13e-186	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00574	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAKMLPPD_00575	9.44e-183	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HAKMLPPD_00576	2.56e-289	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HAKMLPPD_00577	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00578	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_00579	1.34e-183	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAKMLPPD_00580	2.29e-306	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAKMLPPD_00581	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_00582	2.47e-207	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00583	1.42e-196	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00584	3.37e-177	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HAKMLPPD_00585	3.59e-178	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00586	8.18e-243	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HAKMLPPD_00587	2.22e-278	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HAKMLPPD_00588	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00589	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAKMLPPD_00590	2.61e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAKMLPPD_00591	9.24e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAKMLPPD_00592	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HAKMLPPD_00593	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAKMLPPD_00594	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAKMLPPD_00595	4.47e-276	-	-	-	P	-	-	-	Citrate transporter
HAKMLPPD_00597	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HAKMLPPD_00601	2.14e-130	-	-	-	K	-	-	-	acetyltransferase
HAKMLPPD_00602	1.95e-141	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00603	2.05e-155	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00604	1.18e-190	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HAKMLPPD_00605	1.01e-182	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HAKMLPPD_00606	3.46e-245	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAKMLPPD_00607	6.31e-179	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HAKMLPPD_00608	6.93e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAKMLPPD_00609	1.97e-133	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_00610	2.2e-273	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HAKMLPPD_00611	8.62e-174	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HAKMLPPD_00612	2.18e-175	hflK	-	-	O	-	-	-	prohibitin homologues
HAKMLPPD_00613	3.35e-19	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HAKMLPPD_00614	2.01e-98	-	-	-	-	-	-	-	-
HAKMLPPD_00615	8.14e-165	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00616	3.48e-211	-	-	-	M	-	-	-	Conserved repeat domain
HAKMLPPD_00617	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAKMLPPD_00618	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAKMLPPD_00619	5.23e-231	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HAKMLPPD_00620	2.09e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAKMLPPD_00621	4.54e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAKMLPPD_00622	2.39e-113	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HAKMLPPD_00623	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HAKMLPPD_00624	1.28e-256	-	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HAKMLPPD_00625	4.55e-242	yeiI	2.7.1.15, 2.7.1.45, 2.7.1.83	-	G	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HAKMLPPD_00626	5.04e-164	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HAKMLPPD_00627	3.51e-272	-	-	-	C	ko:K19954	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
HAKMLPPD_00628	8.1e-236	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HAKMLPPD_00629	5.23e-312	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAKMLPPD_00630	1.25e-300	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HAKMLPPD_00631	4.56e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HAKMLPPD_00632	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAKMLPPD_00633	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HAKMLPPD_00634	1.47e-45	-	-	-	-	-	-	-	-
HAKMLPPD_00635	6.36e-05	-	-	-	S	-	-	-	Dynamin family
HAKMLPPD_00636	1.48e-196	-	-	-	S	-	-	-	Domain of unknown function DUF87
HAKMLPPD_00637	1.22e-43	-	-	-	S	-	-	-	DNA/RNA non-specific endonuclease
HAKMLPPD_00639	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HAKMLPPD_00640	5.41e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HAKMLPPD_00641	8.18e-287	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAKMLPPD_00642	2.53e-287	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HAKMLPPD_00643	8.99e-254	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HAKMLPPD_00645	2.49e-239	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HAKMLPPD_00647	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAKMLPPD_00648	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAKMLPPD_00649	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAKMLPPD_00650	2.12e-295	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAKMLPPD_00651	2.2e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAKMLPPD_00652	1.21e-98	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAKMLPPD_00653	1.63e-302	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HAKMLPPD_00654	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HAKMLPPD_00655	1.41e-216	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HAKMLPPD_00656	9.04e-137	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HAKMLPPD_00657	1.1e-75	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HAKMLPPD_00658	4.76e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HAKMLPPD_00659	1.06e-68	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HAKMLPPD_00660	1.12e-181	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HAKMLPPD_00661	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAKMLPPD_00662	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAKMLPPD_00663	4.59e-282	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAKMLPPD_00664	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAKMLPPD_00665	3.02e-173	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAKMLPPD_00666	3.54e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAKMLPPD_00667	7.45e-158	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HAKMLPPD_00668	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HAKMLPPD_00669	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HAKMLPPD_00670	1.65e-205	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HAKMLPPD_00671	6.55e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HAKMLPPD_00672	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HAKMLPPD_00673	1.09e-180	-	-	-	C	-	-	-	FMN binding
HAKMLPPD_00674	1.46e-73	-	-	-	-	-	-	-	-
HAKMLPPD_00675	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HAKMLPPD_00676	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HAKMLPPD_00677	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HAKMLPPD_00678	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HAKMLPPD_00679	3.77e-71	-	-	-	-	-	-	-	-
HAKMLPPD_00680	3.33e-102	-	-	-	-	-	-	-	-
HAKMLPPD_00681	4.14e-233	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HAKMLPPD_00682	1.7e-240	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HAKMLPPD_00683	6.65e-121	-	-	-	-	-	-	-	-
HAKMLPPD_00684	1.43e-222	-	-	-	S	-	-	-	Protein of unknown function DUF58
HAKMLPPD_00685	2.96e-230	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HAKMLPPD_00686	9.46e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAKMLPPD_00687	1.13e-105	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HAKMLPPD_00688	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAKMLPPD_00689	1.74e-38	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HAKMLPPD_00690	4.15e-167	-	-	-	-	-	-	-	-
HAKMLPPD_00691	3.53e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HAKMLPPD_00692	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAKMLPPD_00693	6.1e-88	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HAKMLPPD_00694	1.94e-240	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HAKMLPPD_00695	1.2e-236	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HAKMLPPD_00696	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HAKMLPPD_00697	4.88e-307	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HAKMLPPD_00698	5.7e-94	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HAKMLPPD_00699	3.71e-307	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HAKMLPPD_00700	9.51e-178	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HAKMLPPD_00701	9.75e-297	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HAKMLPPD_00702	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HAKMLPPD_00703	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAKMLPPD_00704	0.0	glnP	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00705	4.63e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00706	2.13e-174	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HAKMLPPD_00707	5.91e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HAKMLPPD_00708	1.47e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00709	4.31e-258	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_00710	4.73e-242	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HAKMLPPD_00711	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HAKMLPPD_00712	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HAKMLPPD_00713	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAKMLPPD_00714	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_00715	1.25e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAKMLPPD_00716	1.89e-160	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAKMLPPD_00717	5.76e-308	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAKMLPPD_00720	1.1e-310	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HAKMLPPD_00721	1.23e-151	safC	-	-	S	-	-	-	O-methyltransferase
HAKMLPPD_00722	2.79e-225	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HAKMLPPD_00723	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HAKMLPPD_00724	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HAKMLPPD_00725	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HAKMLPPD_00726	8.83e-107	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HAKMLPPD_00727	2.14e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HAKMLPPD_00728	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HAKMLPPD_00729	3.12e-123	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HAKMLPPD_00730	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAKMLPPD_00731	8.33e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HAKMLPPD_00732	3.16e-241	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
HAKMLPPD_00733	5.21e-182	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_00734	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HAKMLPPD_00735	1.31e-163	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_00736	0.0	-	-	-	T	-	-	-	Histidine kinase
HAKMLPPD_00737	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HAKMLPPD_00738	2.99e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAKMLPPD_00739	7.45e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAKMLPPD_00740	6.53e-77	yccF	-	-	S	-	-	-	Inner membrane component domain
HAKMLPPD_00741	7.74e-17	-	-	-	-	-	-	-	-
HAKMLPPD_00742	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HAKMLPPD_00744	2.86e-180	-	-	-	-	-	-	-	-
HAKMLPPD_00745	2.65e-224	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HAKMLPPD_00746	7.1e-288	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter family protein
HAKMLPPD_00747	1.31e-212	-	-	-	C	ko:K07138	-	ko00000	Domain of unknown function (DUF362)
HAKMLPPD_00748	8.19e-140	-	-	-	F	-	-	-	uridine kinase
HAKMLPPD_00749	5.81e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HAKMLPPD_00750	3.6e-181	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HAKMLPPD_00751	1.57e-180	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAKMLPPD_00752	5.12e-206	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HAKMLPPD_00753	1.46e-299	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HAKMLPPD_00754	3.61e-166	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HAKMLPPD_00755	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HAKMLPPD_00756	1.12e-171	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HAKMLPPD_00757	1.48e-184	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00758	9.02e-311	-	-	-	S	-	-	-	Putative esterase
HAKMLPPD_00759	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HAKMLPPD_00760	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAKMLPPD_00761	6.61e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAKMLPPD_00762	4.29e-297	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HAKMLPPD_00763	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAKMLPPD_00764	2e-219	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HAKMLPPD_00765	1.72e-179	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HAKMLPPD_00766	3.99e-106	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAKMLPPD_00767	6.98e-127	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HAKMLPPD_00768	1.04e-165	-	-	-	E	-	-	-	AzlC protein
HAKMLPPD_00769	2.67e-69	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HAKMLPPD_00770	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
HAKMLPPD_00771	2.73e-50	-	-	-	S	-	-	-	Selenoprotein, putative
HAKMLPPD_00772	6.12e-220	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HAKMLPPD_00773	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HAKMLPPD_00774	3.34e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HAKMLPPD_00775	1.42e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAKMLPPD_00776	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAKMLPPD_00777	7.13e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAKMLPPD_00778	2.81e-96	-	-	-	D	-	-	-	Septum formation initiator
HAKMLPPD_00779	1.62e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HAKMLPPD_00780	1.06e-231	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HAKMLPPD_00782	1.29e-119	-	-	-	-	-	-	-	-
HAKMLPPD_00783	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HAKMLPPD_00784	1.12e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HAKMLPPD_00785	2.04e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAKMLPPD_00786	6.91e-203	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HAKMLPPD_00787	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAKMLPPD_00788	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAKMLPPD_00789	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HAKMLPPD_00790	2.76e-218	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HAKMLPPD_00792	4.81e-299	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HAKMLPPD_00793	5.69e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAKMLPPD_00794	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HAKMLPPD_00795	7.25e-288	-	-	-	-	-	-	-	-
HAKMLPPD_00796	6.14e-93	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HAKMLPPD_00797	4.07e-193	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HAKMLPPD_00798	2.31e-178	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HAKMLPPD_00799	1.99e-238	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAKMLPPD_00800	1.74e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HAKMLPPD_00801	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAKMLPPD_00802	8.46e-133	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HAKMLPPD_00803	3.22e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAKMLPPD_00804	3.19e-179	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HAKMLPPD_00805	7.98e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00806	4.53e-228	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HAKMLPPD_00807	3.88e-207	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAKMLPPD_00808	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HAKMLPPD_00809	3.13e-149	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAKMLPPD_00810	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAKMLPPD_00812	2.25e-202	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HAKMLPPD_00813	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HAKMLPPD_00815	2.04e-09	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HAKMLPPD_00816	5.36e-56	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_00818	1.72e-23	-	-	-	-	-	-	-	-
HAKMLPPD_00819	1.15e-16	-	-	-	-	-	-	-	-
HAKMLPPD_00820	5.01e-154	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HAKMLPPD_00821	5.42e-30	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAKMLPPD_00822	4.03e-103	-	-	-	V	-	-	-	restriction endonuclease
HAKMLPPD_00823	4.72e-78	-	-	-	V	-	-	-	restriction endonuclease
HAKMLPPD_00824	2.3e-212	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HAKMLPPD_00825	4.99e-155	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HAKMLPPD_00826	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAKMLPPD_00827	6.51e-218	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HAKMLPPD_00828	4.34e-159	-	-	-	L	-	-	-	NUDIX domain
HAKMLPPD_00829	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HAKMLPPD_00830	6.96e-264	-	-	-	-	-	-	-	-
HAKMLPPD_00832	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAKMLPPD_00834	1.88e-27	-	-	-	EGP	-	-	-	major facilitator superfamily
HAKMLPPD_00835	6.64e-53	-	-	-	L	ko:K07483	-	ko00000	Transposase
HAKMLPPD_00836	2.63e-164	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HAKMLPPD_00837	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HAKMLPPD_00838	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HAKMLPPD_00839	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HAKMLPPD_00840	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAKMLPPD_00841	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_00842	1.23e-311	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HAKMLPPD_00843	1.54e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAKMLPPD_00844	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HAKMLPPD_00845	3.23e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HAKMLPPD_00846	2.9e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAKMLPPD_00847	5.21e-192	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAKMLPPD_00848	3.17e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAKMLPPD_00849	1.85e-57	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HAKMLPPD_00850	2.14e-163	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HAKMLPPD_00851	8.09e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HAKMLPPD_00852	6.83e-50	-	-	-	-	-	-	-	-
HAKMLPPD_00853	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAKMLPPD_00854	2.91e-104	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAKMLPPD_00855	7.86e-252	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAKMLPPD_00856	1.5e-94	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HAKMLPPD_00857	1.64e-282	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAKMLPPD_00858	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAKMLPPD_00859	3.9e-105	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HAKMLPPD_00860	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HAKMLPPD_00861	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAKMLPPD_00862	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HAKMLPPD_00863	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HAKMLPPD_00864	1.97e-295	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HAKMLPPD_00865	1.33e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HAKMLPPD_00866	9.87e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAKMLPPD_00867	2.13e-130	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HAKMLPPD_00868	1.6e-140	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HAKMLPPD_00869	5.57e-310	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAKMLPPD_00870	3.08e-207	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HAKMLPPD_00872	1.87e-176	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAKMLPPD_00873	8.96e-75	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HAKMLPPD_00874	4.74e-266	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HAKMLPPD_00875	1.14e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAKMLPPD_00876	0.0	corC	-	-	S	-	-	-	CBS domain
HAKMLPPD_00877	2.58e-228	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAKMLPPD_00878	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAKMLPPD_00879	8.06e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HAKMLPPD_00880	1.02e-57	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HAKMLPPD_00881	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAKMLPPD_00882	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00884	8.79e-284	-	-	-	G	-	-	-	Transmembrane secretion effector
HAKMLPPD_00885	2.5e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_00886	3.96e-53	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HAKMLPPD_00887	2.67e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HAKMLPPD_00888	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAKMLPPD_00890	2.96e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAKMLPPD_00891	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAKMLPPD_00892	4.49e-30	yhjX	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major facilitator Superfamily
HAKMLPPD_00893	1.51e-14	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HAKMLPPD_00894	7.32e-248	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HAKMLPPD_00895	8.71e-126	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAKMLPPD_00896	5.6e-93	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAKMLPPD_00897	2.02e-76	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAKMLPPD_00898	7.23e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAKMLPPD_00899	8.14e-290	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HAKMLPPD_00900	8.3e-172	-	-	-	S	-	-	-	UPF0126 domain
HAKMLPPD_00901	7.89e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HAKMLPPD_00902	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAKMLPPD_00903	2.59e-297	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HAKMLPPD_00904	8.04e-187	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HAKMLPPD_00905	0.0	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HAKMLPPD_00906	7.44e-278	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HAKMLPPD_00907	5.48e-298	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAKMLPPD_00908	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HAKMLPPD_00909	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HAKMLPPD_00910	3.85e-98	-	-	-	-	-	-	-	-
HAKMLPPD_00911	0.0	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HAKMLPPD_00912	1.84e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_00913	9.73e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HAKMLPPD_00914	1.67e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HAKMLPPD_00915	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAKMLPPD_00916	1.65e-201	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HAKMLPPD_00917	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HAKMLPPD_00918	8.48e-241	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAKMLPPD_00919	1.06e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HAKMLPPD_00920	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAKMLPPD_00921	1.68e-227	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HAKMLPPD_00922	2.07e-197	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HAKMLPPD_00923	2.35e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAKMLPPD_00924	9.36e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAKMLPPD_00925	1.73e-209	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HAKMLPPD_00926	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAKMLPPD_00928	1.96e-113	arsC	1.20.4.1, 2.8.4.2	-	T	ko:K03741,ko:K18701	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAKMLPPD_00929	7.39e-276	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00930	1.61e-151	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HAKMLPPD_00931	1.29e-64	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HAKMLPPD_00932	3.94e-159	-	-	-	S	-	-	-	SdpI/YhfL protein family
HAKMLPPD_00933	1.18e-134	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HAKMLPPD_00934	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAKMLPPD_00935	5.36e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAKMLPPD_00938	1.81e-81	-	-	-	-	-	-	-	-
HAKMLPPD_00939	1.39e-124	-	-	-	M	-	-	-	Peptidase family M23
HAKMLPPD_00940	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAKMLPPD_00941	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HAKMLPPD_00942	4.53e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HAKMLPPD_00943	2.74e-266	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HAKMLPPD_00944	4.75e-138	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HAKMLPPD_00945	1.54e-20	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAKMLPPD_00946	1.99e-315	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAKMLPPD_00947	3.94e-88	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAKMLPPD_00948	7.33e-183	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HAKMLPPD_00949	2.63e-164	-	-	-	-	-	-	-	-
HAKMLPPD_00951	1.42e-289	-	-	-	K	-	-	-	Fic/DOC family
HAKMLPPD_00953	6.49e-90	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HAKMLPPD_00954	0.0	-	-	-	M	-	-	-	domain protein
HAKMLPPD_00957	1.72e-210	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HAKMLPPD_00958	1.48e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HAKMLPPD_00959	4.53e-181	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HAKMLPPD_00960	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HAKMLPPD_00961	2.65e-129	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HAKMLPPD_00962	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HAKMLPPD_00963	1.18e-225	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HAKMLPPD_00964	7.17e-119	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HAKMLPPD_00965	8.04e-189	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HAKMLPPD_00966	7.04e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HAKMLPPD_00967	7.64e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAKMLPPD_00969	1.09e-51	yoaP	-	-	E	-	-	-	YoaP-like
HAKMLPPD_00970	5.54e-85	yoaP	-	-	E	-	-	-	YoaP-like
HAKMLPPD_00971	8.07e-233	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAKMLPPD_00972	1.02e-141	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HAKMLPPD_00974	5.21e-88	-	-	-	K	-	-	-	MerR family regulatory protein
HAKMLPPD_00975	2.37e-248	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HAKMLPPD_00976	6.18e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HAKMLPPD_00977	2.11e-272	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00978	1.84e-76	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAKMLPPD_00979	0.0	-	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
HAKMLPPD_00980	8.31e-256	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HAKMLPPD_00981	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HAKMLPPD_00982	4.55e-143	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HAKMLPPD_00983	1.84e-87	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAKMLPPD_00985	2.77e-19	-	-	-	-	-	-	-	-
HAKMLPPD_00986	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00987	4.02e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HAKMLPPD_00988	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00989	6.13e-282	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_00990	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAKMLPPD_00991	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAKMLPPD_00992	3.99e-232	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HAKMLPPD_00993	4.41e-218	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HAKMLPPD_00994	2.1e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HAKMLPPD_00995	3.72e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HAKMLPPD_00996	6.64e-190	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAKMLPPD_00997	2.47e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HAKMLPPD_00998	5.27e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAKMLPPD_00999	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HAKMLPPD_01000	4.69e-260	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAKMLPPD_01001	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HAKMLPPD_01002	3.79e-249	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAKMLPPD_01003	9.92e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAKMLPPD_01004	1.58e-201	-	-	-	G	-	-	-	Fructosamine kinase
HAKMLPPD_01005	2.91e-199	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAKMLPPD_01006	9.31e-199	-	-	-	S	-	-	-	PAC2 family
HAKMLPPD_01011	7.46e-21	-	-	-	-	-	-	-	-
HAKMLPPD_01012	2.01e-34	-	-	-	-	-	-	-	-
HAKMLPPD_01013	2.22e-98	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HAKMLPPD_01014	8.77e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAKMLPPD_01015	6.02e-78	-	-	-	-	-	-	-	-
HAKMLPPD_01016	6.93e-180	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HAKMLPPD_01017	9.13e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HAKMLPPD_01018	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HAKMLPPD_01019	1.63e-71	-	-	-	-	-	-	-	-
HAKMLPPD_01020	0.0	-	-	-	K	-	-	-	WYL domain
HAKMLPPD_01021	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HAKMLPPD_01023	2.29e-87	-	-	-	-	-	-	-	-
HAKMLPPD_01024	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HAKMLPPD_01025	9.79e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAKMLPPD_01026	8.03e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAKMLPPD_01027	1.69e-48	-	-	-	-	-	-	-	-
HAKMLPPD_01028	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HAKMLPPD_01029	3.6e-316	-	-	-	-	-	-	-	-
HAKMLPPD_01030	1.1e-205	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAKMLPPD_01031	5.48e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HAKMLPPD_01032	2.15e-129	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAKMLPPD_01033	3.82e-81	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HAKMLPPD_01034	3.38e-256	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAKMLPPD_01035	2.14e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAKMLPPD_01036	5.51e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAKMLPPD_01037	2.38e-172	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HAKMLPPD_01038	3.93e-142	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HAKMLPPD_01039	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAKMLPPD_01040	3.22e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HAKMLPPD_01041	2.68e-64	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HAKMLPPD_01042	3.77e-221	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HAKMLPPD_01043	8.44e-134	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAKMLPPD_01044	1.24e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HAKMLPPD_01045	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HAKMLPPD_01046	9.16e-137	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HAKMLPPD_01047	9.33e-229	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAKMLPPD_01048	8.78e-205	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAKMLPPD_01049	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAKMLPPD_01050	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAKMLPPD_01051	2.17e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAKMLPPD_01052	1.61e-177	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAKMLPPD_01053	1.12e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAKMLPPD_01054	1.32e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HAKMLPPD_01055	6.26e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAKMLPPD_01056	2.04e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HAKMLPPD_01058	6.23e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAKMLPPD_01059	7.33e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HAKMLPPD_01060	1.22e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAKMLPPD_01061	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HAKMLPPD_01062	1.02e-156	-	-	-	-	-	-	-	-
HAKMLPPD_01064	9.63e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAKMLPPD_01065	2.6e-179	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAKMLPPD_01066	2.63e-120	-	-	-	-	-	-	-	-
HAKMLPPD_01067	2.66e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAKMLPPD_01068	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAKMLPPD_01069	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HAKMLPPD_01070	6.16e-283	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
HAKMLPPD_01071	2.88e-136	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HAKMLPPD_01072	2.29e-221	-	-	-	G	-	-	-	Fic/DOC family
HAKMLPPD_01073	4.53e-181	-	-	-	-	-	-	-	-
HAKMLPPD_01074	9.96e-209	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HAKMLPPD_01075	1.71e-121	-	-	-	S	-	-	-	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAKMLPPD_01077	9.73e-115	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HAKMLPPD_01078	5.7e-06	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HAKMLPPD_01079	1.35e-119	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HAKMLPPD_01080	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
HAKMLPPD_01081	2.16e-77	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HAKMLPPD_01082	6.81e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_01083	4.59e-159	-	-	-	S	-	-	-	ABC-2 family transporter protein
HAKMLPPD_01084	1.06e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HAKMLPPD_01085	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HAKMLPPD_01086	6.37e-227	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAKMLPPD_01087	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HAKMLPPD_01088	3.69e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HAKMLPPD_01089	3.49e-167	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HAKMLPPD_01090	7.29e-244	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HAKMLPPD_01091	6.75e-223	-	-	-	L	-	-	-	Tetratricopeptide repeat
HAKMLPPD_01092	6.35e-313	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAKMLPPD_01093	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HAKMLPPD_01094	2.37e-180	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HAKMLPPD_01095	2.36e-122	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAKMLPPD_01096	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HAKMLPPD_01097	2.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAKMLPPD_01098	3.29e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HAKMLPPD_01099	4.69e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAKMLPPD_01100	1.66e-306	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HAKMLPPD_01101	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAKMLPPD_01102	3.26e-274	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAKMLPPD_01103	4.64e-254	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAKMLPPD_01104	8.57e-145	-	-	-	-	-	-	-	-
HAKMLPPD_01105	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HAKMLPPD_01106	9.1e-261	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAKMLPPD_01107	4.82e-196	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAKMLPPD_01108	1.8e-18	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAKMLPPD_01109	7.42e-125	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HAKMLPPD_01111	2.66e-145	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HAKMLPPD_01113	7.24e-08	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HAKMLPPD_01114	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAKMLPPD_01115	5.63e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HAKMLPPD_01116	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAKMLPPD_01117	1.06e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HAKMLPPD_01118	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HAKMLPPD_01119	1.27e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HAKMLPPD_01120	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_01121	9.26e-110	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HAKMLPPD_01122	6.79e-271	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAKMLPPD_01123	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAKMLPPD_01124	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAKMLPPD_01125	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAKMLPPD_01126	0.0	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HAKMLPPD_01127	3.01e-184	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_01128	7.79e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
HAKMLPPD_01129	3.28e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAKMLPPD_01130	9.7e-253	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HAKMLPPD_01131	5.05e-185	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HAKMLPPD_01132	3.73e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HAKMLPPD_01133	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_01134	3.95e-139	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAKMLPPD_01135	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01136	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HAKMLPPD_01137	4.25e-197	-	-	-	L	-	-	-	Excalibur calcium-binding domain
HAKMLPPD_01138	3.21e-147	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HAKMLPPD_01139	1.74e-225	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAKMLPPD_01140	1.81e-108	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAKMLPPD_01141	4.92e-157	-	-	-	S	-	-	-	alpha beta
HAKMLPPD_01143	5.4e-39	-	-	-	-	-	-	-	-
HAKMLPPD_01144	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HAKMLPPD_01145	1.77e-72	-	-	-	S	-	-	-	MazG-like family
HAKMLPPD_01146	9.43e-90	-	-	-	V	-	-	-	Abi-like protein
HAKMLPPD_01149	1.57e-186	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HAKMLPPD_01150	7.18e-92	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HAKMLPPD_01151	4.77e-16	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
HAKMLPPD_01152	1.69e-166	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01153	4.51e-166	-	-	-	S	-	-	-	DUF218 domain
HAKMLPPD_01154	4.02e-300	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAKMLPPD_01155	3.44e-299	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HAKMLPPD_01156	1.63e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HAKMLPPD_01157	1.02e-209	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAKMLPPD_01158	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HAKMLPPD_01159	1.28e-41	-	-	-	-	-	-	-	-
HAKMLPPD_01160	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAKMLPPD_01161	2.65e-269	-	-	-	S	-	-	-	Peptidase dimerisation domain
HAKMLPPD_01162	5.81e-127	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01163	3.3e-221	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAKMLPPD_01164	3.64e-191	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HAKMLPPD_01166	2.02e-141	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HAKMLPPD_01167	6.03e-153	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HAKMLPPD_01168	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HAKMLPPD_01169	3.89e-17	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Oleate hydratase
HAKMLPPD_01171	1.5e-29	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_01172	1.33e-221	guaD	3.5.4.28, 3.5.4.3, 3.5.4.31	-	F	ko:K01487,ko:K12960	ko00230,ko00270,ko01100,map00230,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HAKMLPPD_01173	1.38e-94	-	-	-	L	-	-	-	Helix-turn-helix domain
HAKMLPPD_01175	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HAKMLPPD_01176	4.22e-278	dinF	-	-	V	-	-	-	MatE
HAKMLPPD_01177	3.14e-129	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAKMLPPD_01178	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAKMLPPD_01179	8.34e-109	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HAKMLPPD_01180	8.5e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HAKMLPPD_01181	1.86e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HAKMLPPD_01182	7.71e-295	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HAKMLPPD_01183	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HAKMLPPD_01184	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HAKMLPPD_01185	3.36e-37	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HAKMLPPD_01186	1.02e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HAKMLPPD_01187	1.8e-272	-	-	-	T	-	-	-	Domain of unknown function (DUF4173)
HAKMLPPD_01188	3.95e-274	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAKMLPPD_01189	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HAKMLPPD_01190	3.4e-224	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAKMLPPD_01191	1.49e-151	-	-	-	-	-	-	-	-
HAKMLPPD_01192	6.31e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAKMLPPD_01193	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HAKMLPPD_01194	3.04e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HAKMLPPD_01195	4.31e-127	-	-	-	-	-	-	-	-
HAKMLPPD_01196	1.71e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAKMLPPD_01197	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAKMLPPD_01198	5.45e-153	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAKMLPPD_01199	7.14e-157	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HAKMLPPD_01200	7.06e-271	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAKMLPPD_01201	7.07e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HAKMLPPD_01202	7.73e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAKMLPPD_01203	4.76e-125	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HAKMLPPD_01204	3.69e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAKMLPPD_01205	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HAKMLPPD_01206	1.35e-240	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAKMLPPD_01207	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAKMLPPD_01208	5.49e-198	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HAKMLPPD_01209	1.26e-223	-	-	-	EG	-	-	-	EamA-like transporter family
HAKMLPPD_01210	8.83e-165	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HAKMLPPD_01211	6.07e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HAKMLPPD_01212	2.01e-306	-	-	-	T	-	-	-	Histidine kinase
HAKMLPPD_01213	2.49e-165	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_01214	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HAKMLPPD_01215	6.6e-150	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HAKMLPPD_01216	2.1e-252	-	-	-	T	-	-	-	Histidine kinase
HAKMLPPD_01217	1.72e-242	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_01218	8.53e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAKMLPPD_01219	3.96e-292	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HAKMLPPD_01220	6.4e-265	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAKMLPPD_01221	6.13e-148	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HAKMLPPD_01222	1.19e-311	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01223	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAKMLPPD_01224	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HAKMLPPD_01225	3.75e-129	-	-	-	-	-	-	-	-
HAKMLPPD_01226	1.13e-308	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAKMLPPD_01227	1.81e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HAKMLPPD_01228	4.28e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HAKMLPPD_01229	1.54e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HAKMLPPD_01230	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HAKMLPPD_01231	1.75e-209	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HAKMLPPD_01232	1.62e-203	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01233	7.05e-264	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01234	2.99e-80	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01235	9.4e-72	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01236	2.49e-125	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01237	1.44e-05	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01238	1.32e-218	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HAKMLPPD_01240	2.11e-46	-	-	-	-	-	-	-	-
HAKMLPPD_01241	4.09e-248	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HAKMLPPD_01242	1.59e-244	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HAKMLPPD_01243	2.47e-136	-	-	-	-	-	-	-	-
HAKMLPPD_01244	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HAKMLPPD_01245	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HAKMLPPD_01246	6.41e-193	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HAKMLPPD_01247	8.39e-196	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HAKMLPPD_01248	2.12e-224	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HAKMLPPD_01249	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAKMLPPD_01250	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HAKMLPPD_01251	1.86e-139	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAKMLPPD_01252	1.62e-142	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HAKMLPPD_01253	4.82e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAKMLPPD_01254	8.17e-114	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAKMLPPD_01255	6.57e-220	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAKMLPPD_01256	2.15e-237	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HAKMLPPD_01257	4.37e-50	-	-	-	-	-	-	-	-
HAKMLPPD_01258	3.19e-126	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAKMLPPD_01259	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAKMLPPD_01260	4.92e-242	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HAKMLPPD_01261	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HAKMLPPD_01262	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HAKMLPPD_01263	1.46e-123	-	-	-	F	-	-	-	NUDIX domain
HAKMLPPD_01264	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAKMLPPD_01265	1.73e-253	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01266	9.48e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01267	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAKMLPPD_01268	7.42e-276	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAKMLPPD_01269	4.74e-212	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HAKMLPPD_01270	5.05e-279	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HAKMLPPD_01272	0.0	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HAKMLPPD_01273	6.85e-182	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HAKMLPPD_01274	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HAKMLPPD_01275	1.05e-273	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAKMLPPD_01276	1.74e-259	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HAKMLPPD_01277	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAKMLPPD_01278	8.3e-253	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAKMLPPD_01279	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAKMLPPD_01280	1.96e-196	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAKMLPPD_01281	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HAKMLPPD_01282	2.08e-81	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAKMLPPD_01283	8.17e-242	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAKMLPPD_01284	2.73e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HAKMLPPD_01285	0.0	-	-	-	L	-	-	-	DNA helicase
HAKMLPPD_01286	3.4e-276	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HAKMLPPD_01287	1.01e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAKMLPPD_01288	1.47e-70	-	-	-	M	-	-	-	Lysin motif
HAKMLPPD_01289	6.88e-170	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAKMLPPD_01290	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAKMLPPD_01291	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HAKMLPPD_01292	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAKMLPPD_01293	9.35e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HAKMLPPD_01294	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HAKMLPPD_01295	1.78e-95	-	-	-	-	-	-	-	-
HAKMLPPD_01296	9.13e-71	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
HAKMLPPD_01297	6.29e-49	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HAKMLPPD_01298	5e-277	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HAKMLPPD_01299	6.21e-213	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HAKMLPPD_01300	1.18e-304	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HAKMLPPD_01301	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAKMLPPD_01302	2.38e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HAKMLPPD_01303	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAKMLPPD_01304	3.66e-160	-	-	-	-	-	-	-	-
HAKMLPPD_01305	5.33e-141	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HAKMLPPD_01306	6.19e-284	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAKMLPPD_01307	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAKMLPPD_01308	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HAKMLPPD_01309	4.8e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAKMLPPD_01310	4.61e-120	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAKMLPPD_01311	5.08e-64	-	-	-	V	-	-	-	DivIVA protein
HAKMLPPD_01312	3.73e-54	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HAKMLPPD_01313	5.84e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAKMLPPD_01314	6.62e-279	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAKMLPPD_01315	4.39e-309	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAKMLPPD_01316	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HAKMLPPD_01317	3.3e-137	-	-	-	S	ko:K02664	-	ko00000,ko02035,ko02044	Pilus assembly protein, PilO
HAKMLPPD_01318	8.05e-211	-	-	-	NU	-	-	-	PFAM Fimbrial assembly family protein
HAKMLPPD_01319	5.34e-245	pilM	-	-	NU	ko:K02662	-	ko00000,ko02035,ko02044	Type IV pilus assembly protein PilM;
HAKMLPPD_01320	4.46e-194	pppA	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Bacterial Peptidase A24 N-terminal domain
HAKMLPPD_01321	0.0	-	-	-	-	-	-	-	-
HAKMLPPD_01322	1.36e-292	tapC	-	-	U	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HAKMLPPD_01323	1.43e-50	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
HAKMLPPD_01324	2.56e-134	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HAKMLPPD_01325	2.39e-175	-	-	-	NU	ko:K02671	-	ko00000,ko02035,ko02044	Prokaryotic N-terminal methylation motif
HAKMLPPD_01326	0.0	pilB	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HAKMLPPD_01327	0.0	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HAKMLPPD_01328	0.0	-	-	-	-	-	-	-	-
HAKMLPPD_01329	3.83e-197	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAKMLPPD_01330	1.58e-170	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAKMLPPD_01331	5.87e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HAKMLPPD_01332	3.37e-79	-	-	-	S	-	-	-	Thiamine-binding protein
HAKMLPPD_01333	1.86e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAKMLPPD_01334	1.54e-307	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HAKMLPPD_01335	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HAKMLPPD_01336	2.03e-189	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01337	1.37e-259	-	-	-	P	-	-	-	NMT1/THI5 like
HAKMLPPD_01338	4.35e-283	-	-	-	F	-	-	-	nucleoside hydrolase
HAKMLPPD_01339	8.46e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAKMLPPD_01340	6.87e-172	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HAKMLPPD_01341	0.0	-	-	-	I	-	-	-	acetylesterase activity
HAKMLPPD_01342	5.54e-286	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAKMLPPD_01343	1.19e-277	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAKMLPPD_01344	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HAKMLPPD_01346	3.68e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HAKMLPPD_01347	8.55e-198	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HAKMLPPD_01348	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HAKMLPPD_01349	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HAKMLPPD_01350	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HAKMLPPD_01351	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HAKMLPPD_01352	4.09e-211	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HAKMLPPD_01353	5.01e-150	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HAKMLPPD_01354	2.01e-213	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HAKMLPPD_01355	4.36e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HAKMLPPD_01356	5.64e-192	-	-	-	S	-	-	-	Patatin-like phospholipase
HAKMLPPD_01357	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAKMLPPD_01358	1.95e-226	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
HAKMLPPD_01360	2e-17	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HAKMLPPD_01362	1.54e-224	-	-	-	K	-	-	-	LysR substrate binding domain protein
HAKMLPPD_01363	5.64e-299	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HAKMLPPD_01364	1.47e-153	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HAKMLPPD_01365	3.24e-63	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAKMLPPD_01366	2.48e-252	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAKMLPPD_01367	3.44e-168	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
HAKMLPPD_01368	1.69e-196	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HAKMLPPD_01369	0.0	-	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
HAKMLPPD_01370	2.61e-177	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HAKMLPPD_01371	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
HAKMLPPD_01372	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAKMLPPD_01373	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAKMLPPD_01374	6.91e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HAKMLPPD_01375	3.69e-290	-	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HAKMLPPD_01376	1.73e-242	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
HAKMLPPD_01377	4.63e-182	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HAKMLPPD_01378	1.77e-172	-	-	-	S	-	-	-	Pfam:DUF1498
HAKMLPPD_01379	2.64e-164	-	-	-	K	-	-	-	transcriptional regulator (DeoR family)
HAKMLPPD_01380	5.24e-168	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HAKMLPPD_01381	1.78e-120	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HAKMLPPD_01382	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HAKMLPPD_01383	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_01384	1.27e-138	-	-	-	K	-	-	-	MarR family
HAKMLPPD_01385	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HAKMLPPD_01386	1.94e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_01388	1.57e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HAKMLPPD_01389	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HAKMLPPD_01390	2.21e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_01391	1.73e-307	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HAKMLPPD_01392	1.07e-12	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 43
HAKMLPPD_01393	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HAKMLPPD_01394	4.82e-281	-	-	-	G	-	-	-	MFS/sugar transport protein
HAKMLPPD_01395	3.68e-172	-	-	-	K	-	-	-	transcriptional regulator
HAKMLPPD_01396	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HAKMLPPD_01397	3.33e-302	-	-	-	G	-	-	-	Transporter major facilitator family protein
HAKMLPPD_01398	8.72e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_01399	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HAKMLPPD_01400	1.25e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAKMLPPD_01401	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HAKMLPPD_01402	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HAKMLPPD_01403	2.51e-200	-	-	-	I	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HAKMLPPD_01404	2.61e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAKMLPPD_01405	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HAKMLPPD_01406	7.39e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAKMLPPD_01407	2.41e-55	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAKMLPPD_01409	4.86e-259	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HAKMLPPD_01410	1.8e-162	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HAKMLPPD_01411	1.49e-227	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HAKMLPPD_01412	8.29e-294	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HAKMLPPD_01413	3.85e-92	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HAKMLPPD_01414	5.89e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAKMLPPD_01415	0.0	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01416	1.34e-282	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01417	2.03e-92	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HAKMLPPD_01418	4.72e-134	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HAKMLPPD_01419	0.0	-	-	-	V	-	-	-	Domain of unknown function (DUF3427)
HAKMLPPD_01420	2.94e-99	-	-	-	-	-	-	-	-
HAKMLPPD_01421	1.74e-96	-	-	-	S	-	-	-	Bacterial PH domain
HAKMLPPD_01422	6.8e-313	-	-	-	S	-	-	-	zinc finger
HAKMLPPD_01423	8.74e-281	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
HAKMLPPD_01424	1.41e-265	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
HAKMLPPD_01425	3.36e-248	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01426	1.2e-260	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAKMLPPD_01427	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01428	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01429	1.25e-239	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAKMLPPD_01430	1.58e-202	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HAKMLPPD_01431	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HAKMLPPD_01432	1.35e-93	-	-	-	-	-	-	-	-
HAKMLPPD_01433	4.77e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAKMLPPD_01434	4.88e-64	-	-	-	-	-	-	-	-
HAKMLPPD_01435	3.03e-123	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HAKMLPPD_01436	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HAKMLPPD_01437	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HAKMLPPD_01438	1.34e-233	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01439	2.29e-99	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01440	4.72e-06	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HAKMLPPD_01441	9.7e-19	-	-	-	L	-	-	-	Transposase, Mutator family
HAKMLPPD_01444	1.26e-82	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HAKMLPPD_01447	6.85e-75	yccF	-	-	S	-	-	-	Inner membrane component domain
HAKMLPPD_01448	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01451	6.22e-28	-	-	-	L	-	-	-	Transposase, Mutator family
HAKMLPPD_01452	6.4e-51	-	-	-	L	-	-	-	Transposase, Mutator family
HAKMLPPD_01454	1.02e-36	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
HAKMLPPD_01455	2.09e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01456	1.24e-138	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAKMLPPD_01457	1.45e-47	-	-	-	GM	-	-	-	Polysaccharide pyruvyl transferase
HAKMLPPD_01458	1.5e-37	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAKMLPPD_01459	6.95e-38	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HAKMLPPD_01460	3.64e-37	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
HAKMLPPD_01461	3.58e-110	lpg2	2.4.1.337	GT4	M	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	transferase activity, transferring glycosyl groups
HAKMLPPD_01462	2.98e-70	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HAKMLPPD_01463	9.67e-45	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAKMLPPD_01464	3.52e-30	-	-	-	M	-	-	-	Glycosyl transferase family 8
HAKMLPPD_01466	5.22e-264	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HAKMLPPD_01467	3.13e-275	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
HAKMLPPD_01468	1.09e-256	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01469	2.01e-307	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HAKMLPPD_01470	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAKMLPPD_01471	2.22e-252	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
HAKMLPPD_01472	1.37e-141	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
HAKMLPPD_01473	2.26e-267	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HAKMLPPD_01474	3.76e-245	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01475	1.17e-105	-	-	-	-	-	-	-	-
HAKMLPPD_01476	4.68e-173	-	-	-	G	-	-	-	Acyltransferase family
HAKMLPPD_01477	6.08e-31	-	-	-	G	-	-	-	Acyltransferase family
HAKMLPPD_01478	1.09e-203	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HAKMLPPD_01479	5.28e-41	-	-	-	-	-	-	-	-
HAKMLPPD_01480	1.82e-64	-	-	-	-	-	-	-	-
HAKMLPPD_01481	8.14e-72	-	-	-	-	-	-	-	-
HAKMLPPD_01483	2.68e-136	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01484	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HAKMLPPD_01485	1.56e-144	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01486	1.82e-161	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAKMLPPD_01487	3.56e-239	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01488	1.4e-254	-	-	-	-	-	-	-	-
HAKMLPPD_01489	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HAKMLPPD_01490	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HAKMLPPD_01491	3.73e-240	staP	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HAKMLPPD_01492	2.52e-63	-	-	-	-	-	-	-	-
HAKMLPPD_01493	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HAKMLPPD_01494	3.26e-290	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
HAKMLPPD_01495	3.56e-273	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HAKMLPPD_01496	6.74e-209	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HAKMLPPD_01497	2.2e-165	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HAKMLPPD_01498	1.96e-252	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01499	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01500	1.4e-100	-	-	-	S	-	-	-	Protein conserved in bacteria
HAKMLPPD_01501	1.33e-141	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HAKMLPPD_01502	3.83e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HAKMLPPD_01503	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HAKMLPPD_01504	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAKMLPPD_01505	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HAKMLPPD_01506	3.02e-165	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
HAKMLPPD_01507	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
HAKMLPPD_01508	2.02e-268	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01509	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HAKMLPPD_01510	1.84e-238	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAKMLPPD_01511	1.61e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HAKMLPPD_01512	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAKMLPPD_01513	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HAKMLPPD_01514	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HAKMLPPD_01515	4.64e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HAKMLPPD_01517	5.28e-152	-	-	-	S	-	-	-	CYTH
HAKMLPPD_01518	2.81e-211	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HAKMLPPD_01519	4.27e-227	-	-	-	-	-	-	-	-
HAKMLPPD_01520	1.33e-234	-	-	-	-	-	-	-	-
HAKMLPPD_01521	2.64e-191	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HAKMLPPD_01522	1.54e-155	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HAKMLPPD_01523	2.73e-60	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HAKMLPPD_01524	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAKMLPPD_01525	5.5e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAKMLPPD_01526	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAKMLPPD_01527	1.33e-190	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAKMLPPD_01528	3.17e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAKMLPPD_01529	9.64e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAKMLPPD_01530	6.89e-190	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAKMLPPD_01531	4.87e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAKMLPPD_01533	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HAKMLPPD_01534	6.75e-247	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HAKMLPPD_01535	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HAKMLPPD_01536	4.44e-223	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HAKMLPPD_01537	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HAKMLPPD_01538	2.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAKMLPPD_01539	5.21e-121	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HAKMLPPD_01540	1.09e-173	-	-	-	-	-	-	-	-
HAKMLPPD_01541	1.57e-172	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HAKMLPPD_01542	9.55e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAKMLPPD_01543	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAKMLPPD_01544	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAKMLPPD_01545	0.0	-	-	-	S	-	-	-	domain protein
HAKMLPPD_01546	2.72e-88	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HAKMLPPD_01547	3.12e-104	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HAKMLPPD_01548	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAKMLPPD_01549	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HAKMLPPD_01550	1.43e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HAKMLPPD_01551	8.1e-261	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HAKMLPPD_01552	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAKMLPPD_01553	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAKMLPPD_01554	1.58e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAKMLPPD_01555	5.66e-165	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01556	4.42e-169	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HAKMLPPD_01557	8.52e-135	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAKMLPPD_01558	1.32e-257	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HAKMLPPD_01559	1.39e-119	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Heavy metal translocating P-type atpase
HAKMLPPD_01560	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAKMLPPD_01561	2.26e-208	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HAKMLPPD_01562	8.49e-43	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HAKMLPPD_01563	1.3e-131	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HAKMLPPD_01564	2e-69	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAKMLPPD_01565	1.18e-188	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAKMLPPD_01566	1.09e-84	-	-	-	-	-	-	-	-
HAKMLPPD_01567	7.39e-226	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAKMLPPD_01568	8.04e-117	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
HAKMLPPD_01569	4.5e-177	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HAKMLPPD_01570	1.11e-47	-	-	-	S	-	-	-	zinc-ribbon domain
HAKMLPPD_01574	1.91e-222	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
HAKMLPPD_01575	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAKMLPPD_01576	1.16e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HAKMLPPD_01577	6.16e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAKMLPPD_01578	3.42e-101	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HAKMLPPD_01579	2.04e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HAKMLPPD_01580	2.96e-241	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAKMLPPD_01581	1.37e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAKMLPPD_01582	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HAKMLPPD_01583	9.16e-215	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HAKMLPPD_01584	4.79e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAKMLPPD_01585	5.73e-86	-	-	-	-	-	-	-	-
HAKMLPPD_01586	7.21e-24	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HAKMLPPD_01587	7.04e-31	-	-	-	S	-	-	-	Addiction module toxin, RelE StbE family
HAKMLPPD_01588	1.27e-233	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HAKMLPPD_01589	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HAKMLPPD_01590	1.09e-141	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAKMLPPD_01591	1.13e-91	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
HAKMLPPD_01592	1.36e-133	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
HAKMLPPD_01593	1.35e-107	-	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
HAKMLPPD_01594	1.96e-132	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HAKMLPPD_01595	5.56e-95	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HAKMLPPD_01596	1.77e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAKMLPPD_01597	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAKMLPPD_01598	5.85e-254	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAKMLPPD_01599	6.51e-101	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HAKMLPPD_01600	9.02e-27	-	-	-	-	-	-	-	-
HAKMLPPD_01601	4.29e-297	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HAKMLPPD_01602	2.27e-93	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HAKMLPPD_01606	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HAKMLPPD_01607	4.42e-88	-	-	-	-	-	-	-	-
HAKMLPPD_01608	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HAKMLPPD_01609	9.39e-71	-	-	-	-	-	-	-	-
HAKMLPPD_01610	1.83e-49	-	-	-	T	ko:K06919	-	ko00000	regulation of circadian rhythm
HAKMLPPD_01612	6.93e-18	-	-	-	-	-	-	-	-
HAKMLPPD_01614	3.28e-129	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HAKMLPPD_01616	9.42e-170	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HAKMLPPD_01617	2.69e-34	yuxJ	-	-	EGP	-	-	-	Major facilitator Superfamily
HAKMLPPD_01618	5.43e-182	nfrA	-	-	C	-	-	-	Nitroreductase family
HAKMLPPD_01619	1.02e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HAKMLPPD_01620	6.94e-177	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HAKMLPPD_01621	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01622	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HAKMLPPD_01623	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01624	1.15e-236	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HAKMLPPD_01625	3.67e-230	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01626	7.45e-197	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01627	3.54e-193	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HAKMLPPD_01628	1.96e-135	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HAKMLPPD_01629	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HAKMLPPD_01630	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HAKMLPPD_01631	2.61e-299	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01632	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01633	1.77e-207	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01634	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HAKMLPPD_01635	2.39e-183	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HAKMLPPD_01636	4.28e-181	traX	-	-	S	-	-	-	TraX protein
HAKMLPPD_01637	2.36e-245	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01638	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
HAKMLPPD_01639	2.07e-247	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HAKMLPPD_01640	3.96e-247	-	-	-	M	-	-	-	Cna protein B-type domain
HAKMLPPD_01641	2.18e-227	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAKMLPPD_01642	2.77e-165	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAKMLPPD_01643	2.77e-55	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HAKMLPPD_01644	6.34e-184	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HAKMLPPD_01645	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HAKMLPPD_01646	1.56e-104	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAKMLPPD_01647	6.59e-232	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HAKMLPPD_01648	1.54e-144	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HAKMLPPD_01649	1.75e-62	-	-	-	-	-	-	-	-
HAKMLPPD_01650	3.42e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HAKMLPPD_01652	2.59e-160	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HAKMLPPD_01653	1.84e-21	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
HAKMLPPD_01654	9.45e-235	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAKMLPPD_01655	3.73e-100	-	-	-	-	-	-	-	-
HAKMLPPD_01656	2.66e-137	-	-	-	-	-	-	-	-
HAKMLPPD_01657	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAKMLPPD_01658	0.0	lacZ3	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAKMLPPD_01659	3.07e-175	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HAKMLPPD_01660	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01661	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAKMLPPD_01662	4.56e-266	-	-	-	GK	-	-	-	ROK family
HAKMLPPD_01664	3.28e-203	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HAKMLPPD_01665	1.72e-217	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01666	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01667	6.68e-238	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01668	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAKMLPPD_01669	3.39e-301	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01670	7.7e-196	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01671	1.13e-220	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HAKMLPPD_01672	3.1e-218	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAKMLPPD_01673	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HAKMLPPD_01674	9.44e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAKMLPPD_01675	0.0	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HAKMLPPD_01676	2.15e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HAKMLPPD_01677	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HAKMLPPD_01678	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
HAKMLPPD_01679	0.0	-	-	-	M	-	-	-	probably involved in cell wall
HAKMLPPD_01680	3.95e-242	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01681	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01682	5.38e-208	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01683	7.99e-196	-	-	-	P	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01684	2.18e-296	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HAKMLPPD_01685	2.92e-193	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAKMLPPD_01687	1.73e-270	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HAKMLPPD_01688	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HAKMLPPD_01689	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HAKMLPPD_01690	9.65e-162	-	-	-	-	-	-	-	-
HAKMLPPD_01691	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01692	3.73e-239	-	-	-	G	-	-	-	domain, Protein
HAKMLPPD_01693	4.44e-223	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HAKMLPPD_01694	0.0	-	-	-	G	-	-	-	Alpha galactosidase A
HAKMLPPD_01695	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminus
HAKMLPPD_01696	5.69e-234	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HAKMLPPD_01697	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HAKMLPPD_01698	7.26e-209	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HAKMLPPD_01699	4.33e-190	-	-	-	T	ko:K06950	-	ko00000	HD domain
HAKMLPPD_01700	4.04e-195	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAKMLPPD_01701	4.33e-298	-	-	-	V	-	-	-	ABC transporter permease
HAKMLPPD_01702	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAKMLPPD_01705	8.53e-115	-	-	-	-	-	-	-	-
HAKMLPPD_01706	1.17e-224	-	-	-	S	ko:K21688	-	ko00000	G5
HAKMLPPD_01707	1.37e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HAKMLPPD_01708	1.6e-146	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HAKMLPPD_01709	4.49e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HAKMLPPD_01710	3.31e-262	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HAKMLPPD_01711	3.22e-90	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HAKMLPPD_01712	7.19e-300	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HAKMLPPD_01713	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HAKMLPPD_01714	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
HAKMLPPD_01715	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HAKMLPPD_01716	2.27e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAKMLPPD_01717	2.56e-119	-	-	-	J	-	-	-	TM2 domain
HAKMLPPD_01718	4.61e-253	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HAKMLPPD_01719	8.67e-170	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HAKMLPPD_01720	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HAKMLPPD_01721	9.63e-270	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HAKMLPPD_01722	3.32e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HAKMLPPD_01723	1.13e-181	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HAKMLPPD_01724	3e-315	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HAKMLPPD_01725	2.11e-290	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HAKMLPPD_01726	1.32e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HAKMLPPD_01727	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HAKMLPPD_01728	2.24e-162	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAKMLPPD_01729	8.97e-233	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HAKMLPPD_01730	1e-137	-	-	-	-	-	-	-	-
HAKMLPPD_01731	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAKMLPPD_01732	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAKMLPPD_01733	1.01e-126	-	-	-	T	-	-	-	Forkhead associated domain
HAKMLPPD_01734	9.69e-130	-	-	-	B	-	-	-	Belongs to the OprB family
HAKMLPPD_01735	9.54e-208	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HAKMLPPD_01736	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HAKMLPPD_01737	1.9e-281	-	-	-	S	-	-	-	Protein of unknown function DUF58
HAKMLPPD_01738	3.5e-306	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HAKMLPPD_01739	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HAKMLPPD_01740	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HAKMLPPD_01741	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HAKMLPPD_01742	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HAKMLPPD_01743	3.78e-272	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAKMLPPD_01744	8.79e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAKMLPPD_01745	9.14e-66	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HAKMLPPD_01746	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HAKMLPPD_01747	4.1e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAKMLPPD_01748	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAKMLPPD_01750	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HAKMLPPD_01751	5.16e-219	-	-	-	-	-	-	-	-
HAKMLPPD_01752	0.0	mycP	-	-	O	ko:K14743	-	ko00000,ko01000,ko01002,ko03110	Type VII secretion system ESX-1, transport TM domain B
HAKMLPPD_01753	1.93e-286	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HAKMLPPD_01754	4.48e-64	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HAKMLPPD_01755	1.38e-59	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HAKMLPPD_01757	0.0	vpr	-	-	O	-	-	-	Subtilase family
HAKMLPPD_01758	2.48e-258	-	-	-	-	-	-	-	-
HAKMLPPD_01759	1.23e-216	-	-	-	-	-	-	-	-
HAKMLPPD_01760	5.73e-241	-	-	-	-	-	-	-	-
HAKMLPPD_01761	1.96e-88	-	-	-	-	-	-	-	-
HAKMLPPD_01762	1.44e-256	-	-	-	-	-	-	-	-
HAKMLPPD_01763	2.72e-197	-	-	-	T	-	-	-	Forkhead associated domain
HAKMLPPD_01764	0.0	eccCa	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HAKMLPPD_01765	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAKMLPPD_01766	3.3e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAKMLPPD_01767	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAKMLPPD_01768	4.54e-51	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HAKMLPPD_01769	6.84e-26	-	-	-	G	-	-	-	Major facilitator Superfamily
HAKMLPPD_01770	2.01e-300	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HAKMLPPD_01771	6.2e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAKMLPPD_01772	1.06e-146	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HAKMLPPD_01774	2.76e-101	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01775	4.38e-150	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
HAKMLPPD_01776	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HAKMLPPD_01777	1.38e-127	-	-	-	S	-	-	-	GtrA-like protein
HAKMLPPD_01778	3.71e-274	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HAKMLPPD_01779	2.07e-111	-	-	-	-	-	-	-	-
HAKMLPPD_01780	9.3e-317	-	-	-	T	-	-	-	GHKL domain
HAKMLPPD_01781	1.77e-168	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAKMLPPD_01782	1.26e-268	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAKMLPPD_01783	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HAKMLPPD_01784	7.01e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAKMLPPD_01785	3.2e-293	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HAKMLPPD_01786	6.49e-19	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HAKMLPPD_01787	2.6e-66	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	Addiction module toxin, RelE StbE family
HAKMLPPD_01788	4.23e-61	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HAKMLPPD_01789	4.09e-48	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
HAKMLPPD_01790	9.6e-171	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HAKMLPPD_01791	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HAKMLPPD_01792	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HAKMLPPD_01793	1.91e-107	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAKMLPPD_01794	1.58e-37	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAKMLPPD_01795	6.41e-186	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HAKMLPPD_01796	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HAKMLPPD_01797	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAKMLPPD_01798	3.7e-202	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01799	3.53e-204	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAKMLPPD_01800	3.53e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAKMLPPD_01801	1.66e-291	-	-	-	GK	-	-	-	ROK family
HAKMLPPD_01802	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HAKMLPPD_01803	2.32e-100	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAKMLPPD_01804	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HAKMLPPD_01805	1.84e-193	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HAKMLPPD_01806	2.99e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HAKMLPPD_01807	7.44e-187	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAKMLPPD_01808	6.47e-37	-	-	-	-	-	-	-	-
HAKMLPPD_01809	8.12e-48	-	-	-	-	-	-	-	-
HAKMLPPD_01810	1.09e-254	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAKMLPPD_01811	2.05e-51	-	-	-	-	-	-	-	-
HAKMLPPD_01812	1.85e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAKMLPPD_01813	1.17e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96